BAIAP2L2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene binds phosphoinositides and promotes the formation of planar or curved membrane structures. The encoded protein is found in RAB13-positive vesicles and at intercellular contacts with the plasma membrane. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)8.69365264
2intestinal cholesterol absorption (GO:0030299)7.48347815
3angiotensin maturation (GO:0002003)7.41680944
4regulation of guanylate cyclase activity (GO:0031282)7.16805867
5drug catabolic process (GO:0042737)7.01738048
6drug transmembrane transport (GO:0006855)6.55001204
7actin filament depolymerization (GO:0030042)6.08718948
8drug transport (GO:0015893)5.98569383
9epoxygenase P450 pathway (GO:0019373)5.83147638
10fat-soluble vitamin biosynthetic process (GO:0042362)5.63465056
11exogenous drug catabolic process (GO:0042738)5.37213971
12urate metabolic process (GO:0046415)5.32327002
13renal absorption (GO:0070293)5.22070818
14regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)5.18930725
15modified amino acid transport (GO:0072337)5.16713001
16flavonoid metabolic process (GO:0009812)5.15557736
17positive regulation of guanylate cyclase activity (GO:0031284)5.10652142
18very-low-density lipoprotein particle assembly (GO:0034379)5.05442118
19regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.03124815
20endocrine process (GO:0050886)5.03124815
21regulation of systemic arterial blood pressure by hormone (GO:0001990)5.03124815
22regulation of bile acid biosynthetic process (GO:0070857)4.79806704
23plasma lipoprotein particle assembly (GO:0034377)4.69266911
24regulation of systemic arterial blood pressure (GO:0003073)4.60943517
25NADH metabolic process (GO:0006734)4.56940755
26vitamin A metabolic process (GO:0006776)4.54105122
27polyol transport (GO:0015791)4.48673612
28lysine metabolic process (GO:0006553)4.48454913
29lysine catabolic process (GO:0006554)4.48454913
30peptide catabolic process (GO:0043171)4.43566546
31oligosaccharide catabolic process (GO:0009313)4.43102818
32excretion (GO:0007588)4.42646224
33protein-lipid complex assembly (GO:0065005)4.40613613
34positive regulation of pseudopodium assembly (GO:0031274)4.38677322
35phosphate ion transport (GO:0006817)4.35866978
36membrane repolarization during cardiac muscle cell action potential (GO:0086013)4.32464312
37urea cycle (GO:0000050)4.31243711
38renal system process involved in regulation of blood volume (GO:0001977)4.29074307
39regulation of cGMP biosynthetic process (GO:0030826)4.28086069
40receptor guanylyl cyclase signaling pathway (GO:0007168)4.27245424
41aminoglycoside antibiotic metabolic process (GO:0030647)4.26943888
42bundle of His cell to Purkinje myocyte communication (GO:0086069)4.25564908
43UDP-N-acetylglucosamine metabolic process (GO:0006047)4.23096267
44regulation of cellular extravasation (GO:0002691)4.22783484
45sulfur compound transport (GO:0072348)4.22735811
46digestive system process (GO:0022600)4.21857472
47transepithelial transport (GO:0070633)4.20683576
48urea metabolic process (GO:0019627)4.18295815
49sulfate transmembrane transport (GO:1902358)4.17715994
50organic cation transport (GO:0015695)4.15851442
51adhesion of symbiont to host cell (GO:0044650)4.13915680
52virion attachment to host cell (GO:0019062)4.13915680
53regulation of cholesterol esterification (GO:0010872)4.10399892
54purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.10045822
553-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.10045822
56regulation of triglyceride catabolic process (GO:0010896)4.09240391
57glucose 6-phosphate metabolic process (GO:0051156)4.09132677
58homocysteine metabolic process (GO:0050667)4.08276030
59hormone catabolic process (GO:0042447)3.98676182
60regulation of cholesterol homeostasis (GO:2000188)3.97792147
61nonribosomal peptide biosynthetic process (GO:0019184)3.93383779
62bicarbonate transport (GO:0015701)3.92027130
63cysteine metabolic process (GO:0006534)3.90485774
64regulation of pseudopodium assembly (GO:0031272)3.89987957
65phosphate ion transmembrane transport (GO:0035435)3.86728451
66nitrogen cycle metabolic process (GO:0071941)3.85664493
67membrane repolarization during action potential (GO:0086011)3.83517043
68glutathione biosynthetic process (GO:0006750)3.83179315
69calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.79672114
70phospholipid efflux (GO:0033700)3.77954582
71antibacterial humoral response (GO:0019731)3.74897460
72vitamin transmembrane transport (GO:0035461)3.71063267
73positive regulation of Cdc42 GTPase activity (GO:0043089)3.69566247
74digestion (GO:0007586)3.68838193
75fructose metabolic process (GO:0006000)3.68825137
76response to hepatocyte growth factor (GO:0035728)3.65402852
77cellular response to hepatocyte growth factor stimulus (GO:0035729)3.65402852
78antimicrobial humoral response (GO:0019730)3.64703839
79GDP-mannose metabolic process (GO:0019673)3.61465048
80quaternary ammonium group transport (GO:0015697)3.60926456
81triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.60242276
82response to mercury ion (GO:0046689)3.58368318
83uronic acid metabolic process (GO:0006063)3.57909408
84glucuronate metabolic process (GO:0019585)3.57909408
85positive regulation of digestive system process (GO:0060456)3.54715728
86intestinal epithelial cell development (GO:0060576)3.53016275
87proline metabolic process (GO:0006560)3.52085157
88killing of cells of other organism (GO:0031640)3.49916342
89disruption of cells of other organism (GO:0044364)3.49916342
90trivalent inorganic anion homeostasis (GO:0072506)3.49772476
91phosphate ion homeostasis (GO:0055062)3.49772476
92cGMP-mediated signaling (GO:0019934)3.49387875
93regulation of cGMP metabolic process (GO:0030823)3.49151070
94lipoprotein metabolic process (GO:0042157)3.45292976
95positive regulation of lipid catabolic process (GO:0050996)3.44968886
96glutamine family amino acid biosynthetic process (GO:0009084)3.44472046
97drug metabolic process (GO:0017144)3.42949119
98regulation of vitamin metabolic process (GO:0030656)3.42776865
99renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.42205765
100cytidine catabolic process (GO:0006216)3.40511542
101cytidine deamination (GO:0009972)3.40511542
102cytidine metabolic process (GO:0046087)3.40511542
103nucleoside diphosphate biosynthetic process (GO:0009133)3.40341439
104sulfate transport (GO:0008272)3.39872169
105plasma lipoprotein particle organization (GO:0071827)3.39495790
106positive regulation of glycoprotein biosynthetic process (GO:0010560)3.37554360
107cellular carbohydrate catabolic process (GO:0044275)3.34653555
108phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.33305667
109high-density lipoprotein particle remodeling (GO:0034375)3.33266208
110drinking behavior (GO:0042756)3.32593836
111defense response to fungus (GO:0050832)3.31780351
112protein-lipid complex subunit organization (GO:0071825)3.31731634
113peptide biosynthetic process (GO:0043043)3.31008878
114plasma lipoprotein particle remodeling (GO:0034369)3.30151640
115protein-lipid complex remodeling (GO:0034368)3.30151640
116macromolecular complex remodeling (GO:0034367)3.30151640
117negative regulation of digestive system process (GO:0060457)3.30052066
118positive regulation of respiratory burst (GO:0060267)3.29660150
119glutathione derivative biosynthetic process (GO:1901687)3.29542994
120glutathione derivative metabolic process (GO:1901685)3.29542994
121vitamin D metabolic process (GO:0042359)3.28330696
122cellular response to nitric oxide (GO:0071732)3.24993983
123glycosphingolipid catabolic process (GO:0046479)3.24207641
124regulation of digestive system process (GO:0044058)3.23907189
125diacylglycerol metabolic process (GO:0046339)3.22521313
126glycolipid catabolic process (GO:0019377)3.22172818
127positive regulation of glycoprotein metabolic process (GO:1903020)3.21843638
128short-chain fatty acid metabolic process (GO:0046459)3.19901947
129regulation of respiratory burst (GO:0060263)3.18998491
130arginine metabolic process (GO:0006525)3.18326160
131alkaloid metabolic process (GO:0009820)3.17165184
132vitamin transport (GO:0051180)3.16909773
133adhesion of symbiont to host (GO:0044406)3.15754627
134bile acid and bile salt transport (GO:0015721)3.15686676
135transcytosis (GO:0045056)3.12355298
136maintenance of gastrointestinal epithelium (GO:0030277)3.10958104
137desmosome organization (GO:0002934)3.10837855
138regulation of cholesterol metabolic process (GO:0090181)3.08245850
139cellular response to vitamin D (GO:0071305)3.08006190
140low-density lipoprotein particle remodeling (GO:0034374)3.06948750
141pyrimidine ribonucleoside catabolic process (GO:0046133)3.06207536
142auditory receptor cell differentiation (GO:0042491)3.05525875
143glyoxylate metabolic process (GO:0046487)3.05170132
144proline biosynthetic process (GO:0006561)3.03899471
145response to phenylpropanoid (GO:0080184)3.03365667
146fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.01790613
147O-glycan processing (GO:0016266)3.00994331
148positive regulation of lipoprotein lipase activity (GO:0051006)3.00394504
149positive regulation of triglyceride lipase activity (GO:0061365)3.00394504
150response to nitric oxide (GO:0071731)2.99284100
151ethanol oxidation (GO:0006069)2.98608020
152amino-acid betaine transport (GO:0015838)2.98362578
153carnitine transport (GO:0015879)2.98362578
154sterol homeostasis (GO:0055092)2.97612679
155negative regulation of sterol transport (GO:0032372)2.96937220
156negative regulation of cholesterol transport (GO:0032375)2.96937220
157tricarboxylic acid metabolic process (GO:0072350)2.96896135
158regulation of extracellular matrix disassembly (GO:0010715)2.96699852
159peptide hormone processing (GO:0016486)2.96246561
160phospholipid scrambling (GO:0017121)2.95503402
161cellular glucuronidation (GO:0052695)2.94809476
162lipoprotein transport (GO:0042953)2.93599427

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.62459481
2CDX2_20551321_ChIP-Seq_CACO-2_Human5.45790916
3SOX2_27498859_Chip-Seq_STOMACH_Mouse3.77287343
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.71824670
5HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.68828162
6PPARA_22158963_ChIP-Seq_LIVER_Mouse3.44968234
7GATA4_25053715_ChIP-Seq_YYC3_Human3.28661320
8RXR_22158963_ChIP-Seq_LIVER_Mouse3.21405229
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.05618301
10* GATA6_25053715_ChIP-Seq_YYC3_Human2.96360827
11LXR_22158963_ChIP-Seq_LIVER_Mouse2.84142193
12PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.76089042
13TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.72590480
14THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.64024794
15TRIM28_21343339_ChIP-Seq_HEK293_Human2.52894491
16* SOX2_20726797_ChIP-Seq_SW620_Human2.49438380
17ESR1_21235772_ChIP-Seq_MCF-7_Human2.41358979
18CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.23928703
19CDX2_19796622_ChIP-Seq_MESCs_Mouse2.15656561
20NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.05124241
21ESR2_21235772_ChIP-Seq_MCF-7_Human2.04345151
22MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.96976585
23SRY_22984422_ChIP-ChIP_TESTIS_Rat1.93586178
24* TET1_21451524_ChIP-Seq_MESCs_Mouse1.90006565
25PPAR_26484153_Chip-Seq_NCI-H1993_Human1.87576301
26AR_21909140_ChIP-Seq_LNCAP_Human1.87320176
27STAT6_21828071_ChIP-Seq_BEAS2B_Human1.80548513
28SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.78432316
29RACK7_27058665_Chip-Seq_MCF-7_Human1.76578409
30STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.75673979
31SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.73800469
32FOXO3_23340844_ChIP-Seq_DLD1_Human1.72496173
33NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.70078023
34RUNX1_27514584_Chip-Seq_MCF-7_Human1.66809182
35SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.63401358
36* HNF4A_19822575_ChIP-Seq_HepG2_Human1.62435385
37ELK3_25401928_ChIP-Seq_HUVEC_Human1.60735327
38ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.60060472
39ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.57454369
40KLF5_25053715_ChIP-Seq_YYC3_Human1.57010540
41BCL6_27268052_Chip-Seq_Bcells_Human1.56307687
42KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.55703300
43ATF3_27146783_Chip-Seq_COLON_Human1.52609784
44SA1_27219007_Chip-Seq_Bcells_Human1.52506997
45KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.52349686
46ERG_21242973_ChIP-ChIP_JURKAT_Human1.52206652
47ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.50281169
48TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.47242177
49TCF4_18268006_ChIP-ChIP_LS174T_Human1.46159972
50FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.45739930
51CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.42647095
52RARG_19884340_ChIP-ChIP_MEFs_Mouse1.41144483
53DNAJC2_21179169_ChIP-ChIP_NT2_Human1.40517482
54VDR_21846776_ChIP-Seq_THP-1_Human1.37132556
55UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.36432823
56BP1_19119308_ChIP-ChIP_Hs578T_Human1.32780842
57SA1_27219007_Chip-Seq_ERYTHROID_Human1.31507434
58FOXA2_19822575_ChIP-Seq_HepG2_Human1.30816794
59ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.29447789
60CTCF_27219007_Chip-Seq_ERYTHROID_Human1.28652097
61PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.28604989
62SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.25484668
63JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.24551044
64SMC4_20622854_ChIP-Seq_HELA_Human1.24200922
65FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.20260350
66* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.17800209
67LXR_22292898_ChIP-Seq_THP-1_Human1.17206700
68CLOCK_20551151_ChIP-Seq_293T_Human1.16570983
69RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15363011
70RARA_24833708_ChIP-Seq_LIVER_Mouse1.15035077
71KDM2B_26808549_Chip-Seq_SUP-B15_Human1.15011219
72E2F1_20622854_ChIP-Seq_HELA_Human1.14840216
73CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14227004
74VDR_22108803_ChIP-Seq_LS180_Human1.13613357
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.12665393
76TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12307427
77NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.11834231
78SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.11512800
79* CREB1_26743006_Chip-Seq_LNCaP_Human1.10051491
80EGR1_23403033_ChIP-Seq_LIVER_Mouse1.10008351
81IRF8_22096565_ChIP-ChIP_GC-B_Human1.09905112
82EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09185464
83GATA2_19941826_ChIP-Seq_K562_Human1.08957500
84CTCF_20526341_ChIP-Seq_ESCs_Human1.07289801
85SMAD3_21741376_ChIP-Seq_HESCs_Human1.06666217
86KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06390089
87AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.05303382
88TCF7_22412390_ChIP-Seq_EML_Mouse1.02674149
89ETS1_21867929_ChIP-Seq_TH2_Mouse1.02542376
90BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.02212573
91KDM2B_26808549_Chip-Seq_K562_Human1.01954167
92BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.01944566
93SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.01765141
94ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.00850017
95EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.00765740
96IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00394944
97GATA1_22383799_ChIP-Seq_G1ME_Mouse1.00208159
98NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.99082546
99TCF3_18692474_ChIP-Seq_MEFs_Mouse0.98408555
100FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.98029909
101KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.98008083
102GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.96751979
103OCT4_18692474_ChIP-Seq_MEFs_Mouse0.95636820
104ZNF217_24962896_ChIP-Seq_MCF-7_Human0.94408427
105ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94343336
106EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.93651024
107SALL4_18804426_ChIP-ChIP_XEN_Mouse0.93326420
108* CTCF_27219007_Chip-Seq_Bcells_Human0.92998676
109YY1_22570637_ChIP-Seq_MALME-3M_Human0.92407047
110JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.90876523
111DROSHA_22980978_ChIP-Seq_HELA_Human0.90836761
112ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.90470550
113PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90334361
114PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.89855670
115TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.87829233
116P63_26484246_Chip-Seq_KERATINOCYTES_Human0.87277323
117* TP63_22573176_ChIP-Seq_HFKS_Human0.87233546
118GATA3_24758297_ChIP-Seq_MCF-7_Human0.86869832
119TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86543602
120CTNNB1_20460455_ChIP-Seq_HCT116_Human0.84416463
121STAT3_1855785_ChIP-Seq_MESCs_Mouse0.84415014
122* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.84133743
123FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.83896441
124NANOG_20526341_ChIP-Seq_ESCs_Human0.81442078
125ZNF263_19887448_ChIP-Seq_K562_Human0.81208052
126P68_20966046_ChIP-Seq_HELA_Human0.80409080
127P300_27058665_Chip-Seq_ZR-75-30cells_Human0.79061344
128EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.78929437
129POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.78552279
130CDX2_22108803_ChIP-Seq_LS180_Human0.77390616
131KAP1_22055183_ChIP-Seq_ESCs_Mouse0.76881312
132* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.76347369
133RAD21_21589869_ChIP-Seq_MESCs_Mouse0.75898512
134CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.75278501
135FOXA1_25552417_ChIP-Seq_VCAP_Human0.74376985
136BCOR_27268052_Chip-Seq_Bcells_Human0.73844266
137GATA1_22025678_ChIP-Seq_K562_Human0.73721813
138STAT1_17558387_ChIP-Seq_HELA_Human0.72558208
139PHF8_20622854_ChIP-Seq_HELA_Human0.72119208
140FOXM1_26456572_ChIP-Seq_MCF-7_Human0.71587287

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis9.19964424
2MP0001666_abnormal_nutrient_absorption4.49588590
3MP0004043_abnormal_pH_regulation4.43430481
4MP0002139_abnormal_hepatobiliary_system4.32414686
5MP0010234_abnormal_vibrissa_follicle3.89355910
6MP0004019_abnormal_vitamin_homeostasis3.39806233
7MP0004264_abnormal_extraembryonic_tissu3.19990850
8MP0005085_abnormal_gallbladder_physiolo3.11145111
9MP0003252_abnormal_bile_duct2.86639698
10MP0008875_abnormal_xenobiotic_pharmacok2.83955453
11MP0005332_abnormal_amino_acid2.78145653
12MP0000462_abnormal_digestive_system2.67985566
13MP0009643_abnormal_urine_homeostasis2.63918809
14MP0005377_hearing/vestibular/ear_phenot2.62155667
15MP0003878_abnormal_ear_physiology2.62155667
16MP0005409_darkened_coat_color2.52977677
17MP0001765_abnormal_ion_homeostasis2.45847402
18MP0003866_abnormal_defecation2.42231254
19MP0005365_abnormal_bile_salt2.21164523
20MP0000538_abnormal_urinary_bladder2.12246939
21MP0001756_abnormal_urination2.08268244
22MP0009840_abnormal_foam_cell2.07193172
23MP0003300_gastrointestinal_ulcer2.02667743
24MP0005636_abnormal_mineral_homeostasis1.91395964
25MP0003183_abnormal_peptide_metabolism1.87447571
26MP0001663_abnormal_digestive_system1.86373223
27MP0005670_abnormal_white_adipose1.85020752
28MP0005084_abnormal_gallbladder_morpholo1.82466521
29MP0002136_abnormal_kidney_physiology1.78398215
30MP0005381_digestive/alimentary_phenotyp1.76604976
31MP0002138_abnormal_hepatobiliary_system1.73068092
32MP0010329_abnormal_lipoprotein_level1.71862882
33MP0000537_abnormal_urethra_morphology1.69478704
34MP0001664_abnormal_digestion1.68812416
35MP0004858_abnormal_nervous_system1.66796481
36MP0002822_catalepsy1.60638521
37MP0001873_stomach_inflammation1.54992387
38MP0004147_increased_porphyrin_level1.54522438
39MP0003195_calcinosis1.51488956
40MP0001188_hyperpigmentation1.45088937
41MP0010155_abnormal_intestine_physiology1.44400969
42MP0000490_abnormal_crypts_of1.42744680
43MP0002796_impaired_skin_barrier1.39714794
44MP0000477_abnormal_intestine_morphology1.35264325
45MP0009379_abnormal_foot_pigmentation1.33578983
46MP0005451_abnormal_body_composition1.32181852
47MP0000566_synostosis1.29834410
48MP0002089_abnormal_postnatal_growth/wei1.25854500
49MP0008004_abnormal_stomach_pH1.23661571
50MP0002876_abnormal_thyroid_physiology1.22229398
51MP0003806_abnormal_nucleotide_metabolis1.22078374
52MP0003705_abnormal_hypodermis_morpholog1.15117188
53MP0008961_abnormal_basal_metabolism1.15058224
54MP0003283_abnormal_digestive_organ1.11299756
55MP0004782_abnormal_surfactant_physiolog1.10973413
56MP0010352_gastrointestinal_tract_polyps1.07544043
57MP0003191_abnormal_cellular_cholesterol0.96615991
58MP0000013_abnormal_adipose_tissue0.96346448
59MP0008872_abnormal_physiological_respon0.96094546
60MP0005501_abnormal_skin_physiology0.94785214
61MP0001485_abnormal_pinna_reflex0.93082302
62MP0005319_abnormal_enzyme/_coenzyme0.92669209
63MP0002118_abnormal_lipid_homeostasis0.90374024
64MP0005584_abnormal_enzyme/coenzyme_acti0.90306365
65MP0003315_abnormal_perineum_morphology0.89383612
66MP0000678_abnormal_parathyroid_gland0.87114156
67MP0002098_abnormal_vibrissa_morphology0.87042446
68MP0001764_abnormal_homeostasis0.86358482
69MP0001849_ear_inflammation0.85372016
70MP0003879_abnormal_hair_cell0.83770734
71MP0006054_spinal_hemorrhage0.83536787
72MP0008260_abnormal_autophagy0.81935900
73MP0002971_abnormal_brown_adipose0.81692578
74MP0000230_abnormal_systemic_arterial0.81055316
75MP0005448_abnormal_energy_balance0.78343876
76MP0000609_abnormal_liver_physiology0.75781566
77MP0004885_abnormal_endolymph0.70260068
78MP0005535_abnormal_body_temperature0.68342087
79MP0005375_adipose_tissue_phenotype0.68146620
80MP0005167_abnormal_blood-brain_barrier0.66645006
81MP0001845_abnormal_inflammatory_respons0.64319303
82MP0009384_cardiac_valve_regurgitation0.64292802
83MP0009115_abnormal_fat_cell0.63828949
84MP0006036_abnormal_mitochondrial_physio0.63708903
85MP0001501_abnormal_sleep_pattern0.62208513
86MP0009642_abnormal_blood_homeostasis0.61800049
87MP0005166_decreased_susceptibility_to0.61306927
88MP0009333_abnormal_splenocyte_physiolog0.60397522
89MP0005257_abnormal_intraocular_pressure0.60299622
90MP0003638_abnormal_response/metabolism_0.59046579
91MP0010678_abnormal_skin_adnexa0.58051105
92MP0003329_amyloid_beta_deposits0.57774506
93MP0000467_abnormal_esophagus_morphology0.57735500
94MP0010386_abnormal_urinary_bladder0.57435832
95MP0002896_abnormal_bone_mineralization0.57233316
96MP0000249_abnormal_blood_vessel0.57035838
97MP0001216_abnormal_epidermal_layer0.56020230
98MP0003718_maternal_effect0.54822047
99MP0005083_abnormal_biliary_tract0.53900469
100MP0002166_altered_tumor_susceptibility0.53087730
101MP0000003_abnormal_adipose_tissue0.52722394
102MP0002135_abnormal_kidney_morphology0.51954932
103MP0008469_abnormal_protein_level0.51923607
104MP0003868_abnormal_feces_composition0.49891036
105MP0009053_abnormal_anal_canal0.49452447
106MP0005645_abnormal_hypothalamus_physiol0.48834926
107MP0004484_altered_response_of0.48337929
108MP0002249_abnormal_larynx_morphology0.47323282
109MP0003693_abnormal_embryo_hatching0.46908744
110MP0000604_amyloidosis0.46810239
111MP0000681_abnormal_thyroid_gland0.46579406
112MP0005666_abnormal_adipose_tissue0.46433419
113MP0003453_abnormal_keratinocyte_physiol0.45966033
114MP0005334_abnormal_fat_pad0.45607087
115MP0005310_abnormal_salivary_gland0.45587470
116MP0000613_abnormal_salivary_gland0.45263309
117MP0005058_abnormal_lysosome_morphology0.44622270
118MP0002254_reproductive_system_inflammat0.44553228
119MP0000470_abnormal_stomach_morphology0.41489230
120MP0004947_skin_inflammation0.40301616
121MP0003953_abnormal_hormone_level0.39646897
122MP0002078_abnormal_glucose_homeostasis0.38889786
123MP0009780_abnormal_chondrocyte_physiolo0.38169434
124MP0001191_abnormal_skin_condition0.37113524
125MP0001958_emphysema0.35390582
126MP0003941_abnormal_skin_development0.33901115
127MP0004270_analgesia0.33616614
128MP0000377_abnormal_hair_follicle0.33508649

Predicted human phenotypes

RankGene SetZ-score
1Metabolic alkalosis (HP:0200114)7.00005571
2Abnormality of chloride homeostasis (HP:0011422)6.45433442
3Hyperactive renin-angiotensin system (HP:0000841)6.38539727
4Ileus (HP:0002595)5.99770607
5Abnormality of glutamine family amino acid metabolism (HP:0010902)5.92998926
6Increased circulating renin level (HP:0000848)5.50907782
7Hypokalemic alkalosis (HP:0001949)5.28693424
8Malnutrition (HP:0004395)4.88236194
9Abnormal urine output (HP:0012590)4.85155301
10Hypomagnesemia (HP:0002917)4.70031847
11Abnormality of magnesium homeostasis (HP:0004921)4.58645032
12Abnormality of renal excretion (HP:0011036)4.57426362
13Polyuria (HP:0000103)4.49259982
14Systemic lupus erythematosus (HP:0002725)4.43751948
15Gout (HP:0001997)4.25090630
16Alkalosis (HP:0001948)4.20884880
17Hyperaldosteronism (HP:0000859)4.20216755
18Abnormality of renin-angiotensin system (HP:0000847)4.18254304
19Hyperglycinuria (HP:0003108)4.16977665
20Proximal tubulopathy (HP:0000114)4.14938755
21Abnormality of urine glucose concentration (HP:0011016)4.00888026
22Glycosuria (HP:0003076)4.00888026
23Abnormality of proline metabolism (HP:0010907)3.94990961
24Hydroxyprolinuria (HP:0003080)3.94990961
25Xanthomatosis (HP:0000991)3.91690134
26Abnormality of purine metabolism (HP:0004352)3.69163879
27Widely patent fontanelles and sutures (HP:0004492)3.63496501
28Hemorrhage of the eye (HP:0011885)3.59587587
29Tetany (HP:0001281)3.53521746
30Increased purine levels (HP:0004368)3.53258624
31Hyperuricemia (HP:0002149)3.53258624
32Dehydration (HP:0001944)3.49255136
33Hypercalciuria (HP:0002150)3.47556192
34Renal salt wasting (HP:0000127)3.43525856
35Hyperphosphaturia (HP:0003109)3.42876312
36Right ventricular cardiomyopathy (HP:0011663)3.33089661
37Abnormal drinking behavior (HP:0030082)3.32168383
38Polydipsia (HP:0001959)3.32168383
39Hypokalemia (HP:0002900)3.26304746
40Abnormality of serine family amino acid metabolism (HP:0010894)3.16828263
41Abnormality of glycine metabolism (HP:0010895)3.16828263
42Abnormal urine phosphate concentration (HP:0012599)3.11916408
43Focal segmental glomerulosclerosis (HP:0000097)3.11900794
44Congenital sensorineural hearing impairment (HP:0008527)3.11602866
45Abnormality of the vitamin B12 metabolism (HP:0004341)2.99487659
46Acanthocytosis (HP:0001927)2.96276326
47Delayed epiphyseal ossification (HP:0002663)2.94517612
48Nephrolithiasis (HP:0000787)2.91830893
49Ketoacidosis (HP:0001993)2.89492121
50Conjugated hyperbilirubinemia (HP:0002908)2.86851135
51Facial shape deformation (HP:0011334)2.86272373
52Potter facies (HP:0002009)2.86272373
53Abnormality of vitamin B metabolism (HP:0004340)2.84635245
54Abdominal distention (HP:0003270)2.77716323
55Glomerulonephritis (HP:0000099)2.77614977
56Generalized aminoaciduria (HP:0002909)2.70445854
57Abnormality of nucleobase metabolism (HP:0010932)2.68969842
58Ventricular fibrillation (HP:0001663)2.68578744
59Abnormality of potassium homeostasis (HP:0011042)2.67976733
60Abnormal tarsal ossification (HP:0008369)2.66732983
61Hyperparathyroidism (HP:0000843)2.63487104
62Abnormality of aspartate family amino acid metabolism (HP:0010899)2.59510175
63Hypobetalipoproteinemia (HP:0003563)2.59321583
64Abnormality of complement system (HP:0005339)2.56174117
65Complement deficiency (HP:0004431)2.54631294
66Thin bony cortex (HP:0002753)2.54062509
67Confusion (HP:0001289)2.51246226
68Hypophosphatemia (HP:0002148)2.49730378
69Glomerulosclerosis (HP:0000096)2.47296337
70Autoimmune thrombocytopenia (HP:0001973)2.43486547
71Wide cranial sutures (HP:0010537)2.41592259
72Abnormality of fatty-acid metabolism (HP:0004359)2.39171146
73Growth hormone excess (HP:0000845)2.39120751
74Flat acetabular roof (HP:0003180)2.38863148
75Hyperammonemia (HP:0001987)2.38351763
76Fat malabsorption (HP:0002630)2.38079119
77Metabolic acidosis (HP:0001942)2.36563996
78Pili torti (HP:0003777)2.33199969
79Hyperphosphatemia (HP:0002905)2.31463185
80Megaloblastic anemia (HP:0001889)2.31263869
81Steatorrhea (HP:0002570)2.29873655
82Adrenal overactivity (HP:0002717)2.26915161
83Renal tubular acidosis (HP:0001947)2.23479898
84Cerebral palsy (HP:0100021)2.22904565
85Abnormality of vitamin metabolism (HP:0100508)2.20688991
86Ketosis (HP:0001946)2.18845868
87Posterior subcapsular cataract (HP:0007787)2.16728568
88Cupped ribs (HP:0000887)2.16425203
89Abnormality of sodium homeostasis (HP:0010931)2.16195346
90Hyponatremia (HP:0002902)2.14990503
91Axonal loss (HP:0003447)2.13594942
92Nephritis (HP:0000123)2.11571357
93Myopathic facies (HP:0002058)2.11363190
94Abnormal hair laboratory examination (HP:0003328)2.10465757
95Late onset (HP:0003584)2.08909329
96Hypolipoproteinemia (HP:0010981)2.07183746
97Intrahepatic cholestasis (HP:0001406)2.04751362
98Abnormality of the costochondral junction (HP:0000919)2.03633826
99Subcapsular cataract (HP:0000523)2.02259131
100Abnormality of sulfur amino acid metabolism (HP:0004339)2.01832150
101Nausea (HP:0002018)2.01256746
102Abnormality of alkaline phosphatase activity (HP:0004379)2.00722703
103Vomiting (HP:0002013)1.98339459
104Abnormal enzyme/coenzyme activity (HP:0012379)1.95438189
105Rickets (HP:0002748)1.93161574
106Abnormality of dicarboxylic acid metabolism (HP:0010995)1.92938150
107Dicarboxylic aciduria (HP:0003215)1.92938150
108Hypotension (HP:0002615)1.92742295
109Abnormality of carpal bone ossification (HP:0006257)1.91681059
110Ankle clonus (HP:0011448)1.91286064
111Gastrointestinal dysmotility (HP:0002579)1.90856125
112Distal upper limb amyotrophy (HP:0007149)1.90413975
113Upper limb amyotrophy (HP:0009129)1.90413975
114Decreased circulating renin level (HP:0003351)1.90236212
115Segmental peripheral demyelination/remyelination (HP:0003481)1.89631444
116Protuberant abdomen (HP:0001538)1.89055313
117Pigmentary retinal degeneration (HP:0001146)1.87444590
118Enlarged epiphyses (HP:0010580)1.87387448
119Villous atrophy (HP:0011473)1.87076241
120Abnormality of small intestinal villus morphology (HP:0011472)1.87076241
121Abnormality of pyrimidine metabolism (HP:0004353)1.86290129
122Pancreatitis (HP:0001733)1.86014190
123Syncope (HP:0001279)1.85982686
124Eczematoid dermatitis (HP:0000976)1.85004502
125Vascular calcification (HP:0004934)1.83733096
126Lethargy (HP:0001254)1.82379050
127Chronic diarrhea (HP:0002028)1.82313766
128Symptomatic seizures (HP:0011145)1.81675181
129Abnormal glucose tolerance (HP:0001952)1.79959560
130Abnormality of monocarboxylic acid metabolism (HP:0010996)1.79855542
131Nephrocalcinosis (HP:0000121)1.78689106
132Multiple lipomas (HP:0001012)1.77428849
133Abnormal foot bone ossification (HP:0010675)1.76696792
134Metaphyseal cupping (HP:0003021)1.76594631
135Cardiovascular calcification (HP:0011915)1.74422246
136Stridor (HP:0010307)1.70785386

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK45.85995892
2WNK35.23208545
3LMTK24.75804809
4OXSR14.73607661
5ACVR1B4.73222016
6MST43.94162715
7FRK3.78663377
8MST1R3.71092464
9STK393.14512216
10PRKG22.89593513
11NME12.56972258
12MAP2K22.28732761
13GRK62.27284881
14TAOK22.21449669
15TRIB32.05884411
16RIPK11.97825420
17EPHA21.90738034
18EPHB21.80100242
19STK38L1.74466159
20SIK11.70482791
21MAP3K21.62554692
22TESK21.49461562
23PTK61.41644388
24MAP4K11.40547944
25PBK1.37095599
26MAP3K101.37029588
27MAP2K61.32323796
28CDC42BPA1.25369104
29MAP3K111.23190343
30EPHA41.21683727
31PDK31.13224443
32PDK41.13224443
33MET1.12783813
34MYLK1.09371440
35TESK11.07460547
36TTK1.07369605
37PRKCI1.06341579
38BCKDK1.04370794
39WNK11.02977685
40TAOK11.02179913
41ERN10.95179332
42KSR20.93593666
43NUAK10.93065986
44PTK20.92235193
45TAOK30.89208761
46PRPF4B0.87010000
47AKT30.86692936
48SMG10.83546110
49PDK20.81939313
50TYK20.81257391
51NEK10.80744343
52PIK3CA0.80098296
53FGFR30.77408500
54ICK0.77125879
55PRKAA20.76274389
56STK240.76042567
57ERBB20.75456919
58PRKD20.75142976
59MAP3K80.73242524
60PDGFRA0.72760694
61RIPK40.70817706
62EPHB10.70152708
63PAK40.68882773
64STK100.68715168
65MAP3K10.68612508
66MAP3K70.68343344
67TLK10.67334688
68LATS10.65274458
69MAPK150.64431623
70PRKAA10.61656363
71FER0.59783526
72MAP3K30.59636403
73MAP2K10.59363443
74MAPK110.58857524
75DDR20.58545484
76MAP3K90.55628976
77SGK2230.52556042
78SGK4940.52556042
79LRRK20.52047043
80PAK30.52015805
81PDPK10.47880155
82IRAK30.47530552
83STK380.46751957
84DYRK1B0.46086397
85ABL20.44880611
86EIF2AK10.44482466
87BMX0.41928376
88PIM20.41825579
89MARK20.41334892
90GSK3A0.40065844
91EPHA30.38809756
92RPS6KA20.38633266
93AURKB0.35834269
94ZAP700.35143076
95MATK0.34675434
96CDK190.33415158
97ERBB40.33368813
98SGK30.33145751
99PIK3CG0.33047299
100MAP3K120.32822655
101BRAF0.32740435
102SCYL20.31457297
103DAPK20.30319983
104MAP3K50.30271362
105PRKCA0.29756716
106NME20.28906442
107ARAF0.28834910
108ROCK10.28715050
109TNK20.28298005
110EEF2K0.27209453
111NTRK10.26844940
112SIK20.26756550
113RET0.26232947
114CAMK2G0.26141265
115DMPK0.24083817
116CSNK1A10.24073284
117FGFR40.23895853
118TYRO30.23788990
119GRK10.22989105
120PRKD30.22933289
121PKN20.22123039
122FYN0.21291737
123RPS6KC10.21143423
124RPS6KL10.21143423
125PRKACG0.21000872
126PAK10.20898098
127SGK10.20469024
128PDK10.19611254
129MELK0.19270453
130TBK10.18566850
131ILK0.18086903
132LIMK10.17276882
133CAMK2D0.16969410
134OBSCN0.16191629
135PRKCZ0.16048814
136STK110.15886553
137PRKCD0.14749439
138AKT20.14366115
139SRC0.13809233

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049753.70350441
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.34433301
3Mineral absorption_Homo sapiens_hsa049783.23128233
4Vitamin digestion and absorption_Homo sapiens_hsa049773.14762978
5Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.09757714
6Renin-angiotensin system_Homo sapiens_hsa046143.02444111
7Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.83209431
8Cyanoamino acid metabolism_Homo sapiens_hsa004602.74209310
9Sulfur metabolism_Homo sapiens_hsa009202.70343128
10Protein digestion and absorption_Homo sapiens_hsa049742.28028045
11Pentose and glucuronate interconversions_Homo sapiens_hsa000402.22911522
12Bile secretion_Homo sapiens_hsa049762.21022527
13Starch and sucrose metabolism_Homo sapiens_hsa005002.11435069
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.05263892
15Maturity onset diabetes of the young_Homo sapiens_hsa049502.05228039
16Galactose metabolism_Homo sapiens_hsa000522.05107629
17Carbohydrate digestion and absorption_Homo sapiens_hsa049732.02908577
18Histidine metabolism_Homo sapiens_hsa003402.01455617
19Folate biosynthesis_Homo sapiens_hsa007902.00953338
20Fructose and mannose metabolism_Homo sapiens_hsa000511.95562288
21Tryptophan metabolism_Homo sapiens_hsa003801.92501971
22Butanoate metabolism_Homo sapiens_hsa006501.89975857
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.89153324
24Glutathione metabolism_Homo sapiens_hsa004801.87866051
25Fatty acid degradation_Homo sapiens_hsa000711.79202550
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.78986447
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.76916092
28Pyruvate metabolism_Homo sapiens_hsa006201.74649019
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.72303951
30Arginine and proline metabolism_Homo sapiens_hsa003301.48531705
31Propanoate metabolism_Homo sapiens_hsa006401.46328942
32Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.45028239
33beta-Alanine metabolism_Homo sapiens_hsa004101.39533524
34Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.37627781
35Carbon metabolism_Homo sapiens_hsa012001.33337296
36Nitrogen metabolism_Homo sapiens_hsa009101.33039087
37Glycerolipid metabolism_Homo sapiens_hsa005611.24554635
38Caffeine metabolism_Homo sapiens_hsa002321.23895119
39PPAR signaling pathway_Homo sapiens_hsa033201.21807954
40Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.18229364
41Arginine biosynthesis_Homo sapiens_hsa002201.17030452
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.14166731
43Sulfur relay system_Homo sapiens_hsa041221.13396186
44Peroxisome_Homo sapiens_hsa041461.12614060
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.99081429
46Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96269711
47Oxidative phosphorylation_Homo sapiens_hsa001900.95390813
48Pentose phosphate pathway_Homo sapiens_hsa000300.92866814
49Sphingolipid metabolism_Homo sapiens_hsa006000.89476527
50Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.88452968
51Thyroid hormone synthesis_Homo sapiens_hsa049180.86904820
52Lysine degradation_Homo sapiens_hsa003100.86376256
53Fatty acid metabolism_Homo sapiens_hsa012120.85377503
54Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84018789
55Ether lipid metabolism_Homo sapiens_hsa005650.80909025
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.78130396
57Other glycan degradation_Homo sapiens_hsa005110.77738334
58Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.75843392
59Parkinsons disease_Homo sapiens_hsa050120.74758301
60Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.70850695
61Biosynthesis of amino acids_Homo sapiens_hsa012300.70611330
62Asthma_Homo sapiens_hsa053100.69887673
63Tight junction_Homo sapiens_hsa045300.69107041
64Fatty acid biosynthesis_Homo sapiens_hsa000610.68273394
65Gastric acid secretion_Homo sapiens_hsa049710.66957652
66ABC transporters_Homo sapiens_hsa020100.58324950
67Drug metabolism - other enzymes_Homo sapiens_hsa009830.57788168
68Chemical carcinogenesis_Homo sapiens_hsa052040.57225100
69Alzheimers disease_Homo sapiens_hsa050100.57033769
70Staphylococcus aureus infection_Homo sapiens_hsa051500.56407164
71Pancreatic secretion_Homo sapiens_hsa049720.55603135
72Arachidonic acid metabolism_Homo sapiens_hsa005900.55470410
73Tyrosine metabolism_Homo sapiens_hsa003500.54280075
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.51715257
75Allograft rejection_Homo sapiens_hsa053300.51285469
76Metabolic pathways_Homo sapiens_hsa011000.50640385
77Collecting duct acid secretion_Homo sapiens_hsa049660.50017626
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49496398
79Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48917121
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48662715
81Complement and coagulation cascades_Homo sapiens_hsa046100.47696084
82Autoimmune thyroid disease_Homo sapiens_hsa053200.47098383
83Insulin resistance_Homo sapiens_hsa049310.46635168
84Retinol metabolism_Homo sapiens_hsa008300.45809306
85Vibrio cholerae infection_Homo sapiens_hsa051100.45397428
86Phenylalanine metabolism_Homo sapiens_hsa003600.43603609
87Selenocompound metabolism_Homo sapiens_hsa004500.43453352
88Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.40486391
89Graft-versus-host disease_Homo sapiens_hsa053320.40306159
90Cardiac muscle contraction_Homo sapiens_hsa042600.39130380
91Bladder cancer_Homo sapiens_hsa052190.39067349
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.38739160
93Huntingtons disease_Homo sapiens_hsa050160.36901606
94Glucagon signaling pathway_Homo sapiens_hsa049220.36379437
95Steroid hormone biosynthesis_Homo sapiens_hsa001400.34288324
96Type I diabetes mellitus_Homo sapiens_hsa049400.34066627
97Renin secretion_Homo sapiens_hsa049240.31208155
98Glycerophospholipid metabolism_Homo sapiens_hsa005640.29658758
99Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.28751370
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.25429729
101Steroid biosynthesis_Homo sapiens_hsa001000.24595707
102Cocaine addiction_Homo sapiens_hsa050300.24448116
103GnRH signaling pathway_Homo sapiens_hsa049120.22382650
104Hepatitis C_Homo sapiens_hsa051600.19232669
105AMPK signaling pathway_Homo sapiens_hsa041520.19168540
106Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.16914133
107Pertussis_Homo sapiens_hsa051330.15902500
108Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.15161436
109Prion diseases_Homo sapiens_hsa050200.14816562
110Linoleic acid metabolism_Homo sapiens_hsa005910.14736072
111Primary bile acid biosynthesis_Homo sapiens_hsa001200.13032377
112Fatty acid elongation_Homo sapiens_hsa000620.12982036
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.10759583
114Cysteine and methionine metabolism_Homo sapiens_hsa002700.10393115
115Inositol phosphate metabolism_Homo sapiens_hsa005620.10332680
116Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.08843955
117Aldosterone synthesis and secretion_Homo sapiens_hsa049250.07740084
118Antigen processing and presentation_Homo sapiens_hsa046120.07603337
119Choline metabolism in cancer_Homo sapiens_hsa052310.07017521
120Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.06994457
121Insulin secretion_Homo sapiens_hsa049110.06738313
122Insulin signaling pathway_Homo sapiens_hsa049100.06434964
123Salivary secretion_Homo sapiens_hsa049700.04342975
124Toxoplasmosis_Homo sapiens_hsa051450.04128162
125Intestinal immune network for IgA production_Homo sapiens_hsa046720.03655364
126Thyroid cancer_Homo sapiens_hsa052160.03623313
127Glycosaminoglycan degradation_Homo sapiens_hsa005310.03542298
128Adherens junction_Homo sapiens_hsa045200.02684201
129Salmonella infection_Homo sapiens_hsa051320.00671052

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