BACH2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)7.63334798
2regulation of gamma-delta T cell differentiation (GO:0045586)5.92192585
3B cell receptor signaling pathway (GO:0050853)5.85320677
4regulation of gamma-delta T cell activation (GO:0046643)5.52933192
5V(D)J recombination (GO:0033151)5.28602861
6positive regulation of B cell differentiation (GO:0045579)5.09220112
7positive thymic T cell selection (GO:0045059)4.55122591
8regulation of B cell differentiation (GO:0045577)4.50638272
9T cell selection (GO:0045058)4.43110940
10negative thymic T cell selection (GO:0045060)4.38573224
11negative T cell selection (GO:0043383)4.33658110
12positive regulation by host of viral transcription (GO:0043923)4.16121423
13positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.12979545
14positive regulation of gene expression, epigenetic (GO:0045815)4.11182283
15positive T cell selection (GO:0043368)4.05476377
16regulation of interleukin-12 biosynthetic process (GO:0045075)4.04712856
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.03573018
18negative regulation of cell killing (GO:0031342)4.03573018
19response to interleukin-15 (GO:0070672)4.00509615
20regulation of alpha-beta T cell proliferation (GO:0046640)3.95826035
21regulation of histone H3-K9 methylation (GO:0051570)3.95004681
22T cell homeostasis (GO:0043029)3.92619011
23serine transport (GO:0032329)3.92179639
24regulation of thymocyte apoptotic process (GO:0070243)3.91154255
25L-serine transport (GO:0015825)3.84492843
26negative regulation of histone methylation (GO:0031061)3.81014192
27thymic T cell selection (GO:0045061)3.78839247
28histone H3-K4 trimethylation (GO:0080182)3.77668855
29tolerance induction (GO:0002507)3.77588595
30negative regulation of T-helper cell differentiation (GO:0045623)3.77060795
31negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.77060795
32T cell differentiation in thymus (GO:0033077)3.73198801
33cellular response to interleukin-15 (GO:0071350)3.72935912
34cellular response to ethanol (GO:0071361)3.57432247
35antigen receptor-mediated signaling pathway (GO:0050851)3.56872257
36histone H3-K36 demethylation (GO:0070544)3.54075224
37lymphocyte homeostasis (GO:0002260)3.52855580
38B cell proliferation (GO:0042100)3.52767985
39protein-DNA complex disassembly (GO:0032986)3.47111286
40nucleosome disassembly (GO:0006337)3.47111286
41positive regulation of interleukin-2 production (GO:0032743)3.43794559
42negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.43223839
43T cell lineage commitment (GO:0002360)3.42906833
44T cell differentiation (GO:0030217)3.41857297
45positive regulation of alpha-beta T cell proliferation (GO:0046641)3.36263309
46regulation of B cell proliferation (GO:0030888)3.27902000
47positive regulation of granulocyte differentiation (GO:0030854)3.27345782
48negative regulation of alpha-beta T cell differentiation (GO:0046639)3.27326232
49cytoplasmic mRNA processing body assembly (GO:0033962)3.25802544
50regulation of interleukin-2 biosynthetic process (GO:0045076)3.25672852
51positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.25609850
52mitotic sister chromatid cohesion (GO:0007064)3.24534117
53regulation of B cell receptor signaling pathway (GO:0050855)3.23507524
54CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.21730283
55histone H3-K9 demethylation (GO:0033169)3.21099842
56regulation of telomere maintenance via telomerase (GO:0032210)3.18633767
57negative regulation of gene silencing (GO:0060969)3.18507469
58B cell homeostasis (GO:0001782)3.18146651
59dentate gyrus development (GO:0021542)3.18070981
60Peyers patch development (GO:0048541)3.16887002
61mucosal-associated lymphoid tissue development (GO:0048537)3.16887002
62natural killer cell differentiation (GO:0001779)3.16316691
63histone H3-K4 methylation (GO:0051568)3.15462483
64T cell costimulation (GO:0031295)3.13724317
65regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.12152441
66positive regulation of B cell activation (GO:0050871)3.11232485
67lymphocyte costimulation (GO:0031294)3.06559447
68regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.05775376
69regulation of superoxide anion generation (GO:0032928)3.04534620
70regulation of chromatin silencing (GO:0031935)3.02737635
71regulation of platelet aggregation (GO:0090330)3.00817573
72regulation of germinal center formation (GO:0002634)3.00476558
73positive regulation of B cell proliferation (GO:0030890)3.00407130
74leukocyte homeostasis (GO:0001776)2.98608611
75somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.98362248
76somatic cell DNA recombination (GO:0016444)2.98362248
77somatic diversification of immune receptors (GO:0002200)2.96953258
78interferon-gamma production (GO:0032609)2.95246207
79negative regulation of T cell differentiation (GO:0045581)2.94709981
80alpha-beta T cell differentiation (GO:0046632)2.87582686
81alternative mRNA splicing, via spliceosome (GO:0000380)2.87416874
82positive regulation of protein homooligomerization (GO:0032464)2.86732215
83negative regulation of T cell apoptotic process (GO:0070233)2.86708734
84T cell receptor signaling pathway (GO:0050852)2.83475381
85hepatocyte apoptotic process (GO:0097284)2.81103612
86regulation of histone methylation (GO:0031060)2.79887276
87lymph vessel development (GO:0001945)2.79700944
88behavioral response to nicotine (GO:0035095)2.77821623
89activated T cell proliferation (GO:0050798)2.77598270
90histone lysine demethylation (GO:0070076)2.75099126
91positive regulation of mast cell degranulation (GO:0043306)2.74285665
92positive regulation of mast cell activation involved in immune response (GO:0033008)2.74285665
93regulation of alpha-beta T cell differentiation (GO:0046637)2.74080289
94neural tube formation (GO:0001841)2.73635698
95histone H4 acetylation (GO:0043967)2.73276017
96somite development (GO:0061053)2.73181660
97negative regulation of B cell proliferation (GO:0030889)2.71914859
98positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.71240508
99regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.71240508
100regulation of alpha-beta T cell activation (GO:0046634)2.70901495
101leukocyte aggregation (GO:0070486)2.70384417
102regulation of B cell activation (GO:0050864)2.70216540
103B cell differentiation (GO:0030183)2.70057099
104negative regulation of thymocyte apoptotic process (GO:0070244)2.69268048
105regulation of T cell tolerance induction (GO:0002664)2.67958478
106positive regulation of immunoglobulin production (GO:0002639)2.67254193
107regulation of isotype switching to IgG isotypes (GO:0048302)2.66675664
108positive regulation of isotype switching (GO:0045830)2.66322050
109peptidyl-lysine trimethylation (GO:0018023)2.65682597
110adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.65601243
111negative regulation of alpha-beta T cell activation (GO:0046636)2.65542807
112replicative senescence (GO:0090399)2.65307183
113lymphocyte differentiation (GO:0030098)2.65282384
114immune response-activating cell surface receptor signaling pathway (GO:0002429)2.65216415
115monoubiquitinated protein deubiquitination (GO:0035520)2.64692492
116interkinetic nuclear migration (GO:0022027)2.63508519
117pyrimidine nucleobase catabolic process (GO:0006208)2.63402113
118regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.61498776
119lymphocyte proliferation (GO:0046651)2.60627805
120defense response to protozoan (GO:0042832)2.60550706
121negative regulation of mast cell activation (GO:0033004)2.60516368
122B cell activation (GO:0042113)2.60327181
123negative regulation of RNA splicing (GO:0033119)2.59899932
124germinal center formation (GO:0002467)2.59603419
125regulation of regulatory T cell differentiation (GO:0045589)2.59600730
126negative regulation of T cell mediated immunity (GO:0002710)2.59267950
127regulation of interleukin-2 production (GO:0032663)2.58783912
128histone demethylation (GO:0016577)2.58646729
129mononuclear cell proliferation (GO:0032943)2.58643407
130myeloid dendritic cell differentiation (GO:0043011)2.57665000
131myeloid dendritic cell activation (GO:0001773)2.56933369
132phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.56651568
133positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.55266657
134regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.55266657
135regulation of granulocyte differentiation (GO:0030852)2.55085717
136mast cell activation involved in immune response (GO:0002279)2.53056732
137mast cell degranulation (GO:0043303)2.53056732
138antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.51497656
139alpha-beta T cell activation (GO:0046631)2.49963254
140histone H3-K9 modification (GO:0061647)2.47705368
141hindbrain development (GO:0030902)2.46079947
142antigen processing and presentation of endogenous antigen (GO:0019883)2.45906962
143CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.44731934
144T-helper cell differentiation (GO:0042093)2.44731934
145negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.44099937
146labyrinthine layer development (GO:0060711)2.43924247
147regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.43411517
148hypothalamus development (GO:0021854)2.43340131
149CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.43264460
150cell proliferation in forebrain (GO:0021846)2.42546522
151histone H3-K9 methylation (GO:0051567)2.42047497
152antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.41841173
153mast cell activation (GO:0045576)2.41518734

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.77804521
2E2F7_22180533_ChIP-Seq_HELA_Human5.76555370
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.18587451
4MYC_22102868_ChIP-Seq_BL_Human5.17302303
5* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.51365098
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.48461972
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.48422376
8TP63_19390658_ChIP-ChIP_HaCaT_Human3.31680946
9EZH2_22144423_ChIP-Seq_EOC_Human3.26604128
10* RUNX_20019798_ChIP-Seq_JUKART_Human3.12753051
11VDR_21846776_ChIP-Seq_THP-1_Human3.05772355
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.99918193
13* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.98756401
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.98548003
15VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.82537291
16IRF8_22096565_ChIP-ChIP_GC-B_Human2.55849992
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.54412761
18* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.51753610
19MYB_26560356_Chip-Seq_TH2_Human2.51157782
20CIITA_25753668_ChIP-Seq_RAJI_Human2.43823637
21MAF_26560356_Chip-Seq_TH1_Human2.38741566
22* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.37119079
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.32244240
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.32062157
25MYB_26560356_Chip-Seq_TH1_Human2.30490123
26UTX_26944678_Chip-Seq_JUKART_Human2.28625533
27GBX2_23144817_ChIP-Seq_PC3_Human2.22476258
28TCF7_22412390_ChIP-Seq_EML_Mouse2.17150546
29GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.14762581
30IGF1R_20145208_ChIP-Seq_DFB_Human2.13616427
31MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.12608770
32ZFP57_27257070_Chip-Seq_ESCs_Mouse2.10910224
33* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.08011274
34* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.91163326
35STAT4_19710469_ChIP-ChIP_TH1__Mouse1.89193440
36VDR_24763502_ChIP-Seq_THP-1_Human1.87946210
37ZNF274_21170338_ChIP-Seq_K562_Hela1.87681379
38KDM2B_26808549_Chip-Seq_DND41_Human1.85879400
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.83601256
40RBPJ_22232070_ChIP-Seq_NCS_Mouse1.81723092
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76784099
42CBX2_27304074_Chip-Seq_ESCs_Mouse1.69710831
43SCL_19346495_ChIP-Seq_HPC-7_Human1.67976932
44RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.67545414
45JARID2_20064375_ChIP-Seq_MESCs_Mouse1.65698084
46EWS_26573619_Chip-Seq_HEK293_Human1.58660836
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.56322687
48STAT6_21828071_ChIP-Seq_BEAS2B_Human1.55638955
49KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.55092934
50IRF1_19129219_ChIP-ChIP_H3396_Human1.53390505
51BMI1_23680149_ChIP-Seq_NPCS_Mouse1.52779120
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.52179196
53REST_21632747_ChIP-Seq_MESCs_Mouse1.47691898
54PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.46446943
55KDM2B_26808549_Chip-Seq_JURKAT_Human1.45898297
56FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.45836580
57POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45306152
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44749023
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.43896441
60FUS_26573619_Chip-Seq_HEK293_Human1.43817863
61MAF_26560356_Chip-Seq_TH2_Human1.41066406
62ER_23166858_ChIP-Seq_MCF-7_Human1.39375688
63NOTCH1_21737748_ChIP-Seq_TLL_Human1.39110569
64IRF8_27001747_Chip-Seq_BMDM_Mouse1.37503530
65* PRDM14_20953172_ChIP-Seq_ESCs_Human1.37329943
66EZH2_27304074_Chip-Seq_ESCs_Mouse1.36145846
67RNF2_27304074_Chip-Seq_NSC_Mouse1.34937356
68P300_19829295_ChIP-Seq_ESCs_Human1.31626654
69GATA3_27048872_Chip-Seq_THYMUS_Human1.24087076
70SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.21781591
71CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.21181258
72* TCF4_23295773_ChIP-Seq_U87_Human1.20683828
73* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20530538
74BP1_19119308_ChIP-ChIP_Hs578T_Human1.19828638
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.18922661
76* STAT3_23295773_ChIP-Seq_U87_Human1.18861386
77* SPI1_23127762_ChIP-Seq_K562_Human1.18845814
78FLI1_27457419_Chip-Seq_LIVER_Mouse1.18350675
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18027476
80IRF8_21731497_ChIP-ChIP_J774_Mouse1.17026656
81MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13698010
82SALL1_21062744_ChIP-ChIP_HESCs_Human1.13615673
83* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12180425
84VDR_22108803_ChIP-Seq_LS180_Human1.10992464
85RUNX1_22412390_ChIP-Seq_EML_Mouse1.10455266
86SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.10388299
87AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.09036708
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08711069
89E2F1_21310950_ChIP-Seq_MCF-7_Human1.07880589
90ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.07354831
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.06747801
92* SMAD4_21799915_ChIP-Seq_A2780_Human1.06428751
93PKCTHETA_26484144_Chip-Seq_BREAST_Human1.05692742
94BCAT_22108803_ChIP-Seq_LS180_Human1.05191037
95* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.05189695
96SPI1_23547873_ChIP-Seq_NB4_Human1.03986001
97IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.03966317
98JARID2_20075857_ChIP-Seq_MESCs_Mouse1.02409836
99NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.02329986
100* RNF2_27304074_Chip-Seq_ESCs_Mouse1.01587805
101KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.01156913
102KDM2B_26808549_Chip-Seq_REH_Human1.00702585
103* AR_25329375_ChIP-Seq_VCAP_Human1.00344769
104PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99782633
105* REST_18959480_ChIP-ChIP_MESCs_Mouse0.98603811
106BRD4_27068464_Chip-Seq_AML-cells_Mouse0.95964332
107OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95658072
108* SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.94029212
109PCGF2_27294783_Chip-Seq_ESCs_Mouse0.93418277
110ZFP281_27345836_Chip-Seq_ESCs_Mouse0.93341019
111GATA3_26560356_Chip-Seq_TH2_Human0.92838681
112* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92765487
113NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.92231987
114NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92227979
115MYC_18940864_ChIP-ChIP_HL60_Human0.91968278
116SUZ12_27294783_Chip-Seq_NPCs_Mouse0.90876433
117RUNX2_22187159_ChIP-Seq_PCA_Human0.90149056
118GATA2_22383799_ChIP-Seq_G1ME_Mouse0.90134931
119TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89496932
120TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89020045
121POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89020045
122* EZH2_27294783_Chip-Seq_ESCs_Mouse0.88964522
123AR_21572438_ChIP-Seq_LNCaP_Human0.88591860
124NANOG_18555785_Chip-Seq_ESCs_Mouse0.87620557
125* CBP_20019798_ChIP-Seq_JUKART_Human0.87376810
126* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87376810
127GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87205287
128TP53_22573176_ChIP-Seq_HFKS_Human0.86430096
129EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.85875997
130RXR_22108803_ChIP-Seq_LS180_Human0.85784297
131TAF15_26573619_Chip-Seq_HEK293_Human0.85564392
132YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.84667595
133FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.84208894
134CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.84017135
135DROSHA_22980978_ChIP-Seq_HELA_Human0.83880867
136ARNT_22903824_ChIP-Seq_MCF-7_Human0.83689311
137VDR_24787735_ChIP-Seq_THP-1_Human0.82754263
138MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.80386751
139* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.80310636
140HOXB4_20404135_ChIP-ChIP_EML_Mouse0.80283224
141PU_27001747_Chip-Seq_BMDM_Mouse0.79175056
142* FOXP3_21729870_ChIP-Seq_TREG_Human0.77938453
143SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.77048827
144* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.74881692
145TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.74413303
146CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.74135077
147ELF1_17652178_ChIP-ChIP_JURKAT_Human0.73723660
148MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.73591294
149KDM5A_27292631_Chip-Seq_BREAST_Human0.73281563
150* SMRT_27268052_Chip-Seq_Bcells_Human0.73207747
151GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.72540702
152STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.71980436
153CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.71462670
154GATA3_26560356_Chip-Seq_TH1_Human0.71083941
155EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.69399891
156* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.67097737
157SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.66871180
158TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.65617912
159POU5F1_16153702_ChIP-ChIP_HESCs_Human0.65464282
160* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.60858910
161WDR5_24793694_ChIP-Seq_LNCAP_Human0.58908088
162* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.58719900
163* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.57557374
164ELK3_25401928_ChIP-Seq_HUVEC_Human0.57536572
165ETS1_22383799_ChIP-Seq_G1ME_Mouse0.56728150

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0001800_abnormal_humoral_immune4.01196192
2MP0001790_abnormal_immune_system3.68000616
3MP0005387_immune_system_phenotype3.68000616
4MP0003303_peritoneal_inflammation3.45526633
5MP0000685_abnormal_immune_system3.44600805
6MP0003763_abnormal_thymus_physiology3.32009741
7MP0002396_abnormal_hematopoietic_system3.29168258
8MP0001835_abnormal_antigen_presentation3.03544475
9* MP0002398_abnormal_bone_marrow2.86151754
10MP0005671_abnormal_response_to2.79828744
11* MP0002452_abnormal_antigen_presenting2.77090552
12MP0000703_abnormal_thymus_morphology2.55344143
13MP0002166_altered_tumor_susceptibility2.51064971
14* MP0002723_abnormal_immune_serum2.44533711
15* MP0002420_abnormal_adaptive_immunity2.43542826
16* MP0000716_abnormal_immune_system2.37277307
17* MP0000689_abnormal_spleen_morphology2.36667194
18* MP0001819_abnormal_immune_cell2.34895278
19MP0008057_abnormal_DNA_replication2.27455650
20MP0005000_abnormal_immune_tolerance2.24433313
21* MP0002722_abnormal_immune_system2.15358293
22MP0004808_abnormal_hematopoietic_stem2.08736695
23MP0003300_gastrointestinal_ulcer2.04665245
24MP0000569_abnormal_digit_pigmentation2.03752398
25MP0003787_abnormal_imprinting2.03025824
26MP0002876_abnormal_thyroid_physiology2.03020289
27MP0010094_abnormal_chromosome_stability1.99507604
28MP0005423_abnormal_somatic_nervous1.90893724
29* MP0002429_abnormal_blood_cell1.89566919
30MP0003866_abnormal_defecation1.77996591
31MP0003646_muscle_fatigue1.73114326
32MP0002006_tumorigenesis1.72362331
33MP0003436_decreased_susceptibility_to1.71826812
34MP0002405_respiratory_system_inflammati1.70311368
35MP0001986_abnormal_taste_sensitivity1.66599894
36MP0006054_spinal_hemorrhage1.66003337
37MP0003724_increased_susceptibility_to1.60574107
38MP0002102_abnormal_ear_morphology1.60245865
39MP0001873_stomach_inflammation1.58761484
40MP0000465_gastrointestinal_hemorrhage1.57930225
41MP0004142_abnormal_muscle_tone1.57520912
42MP0005075_abnormal_melanosome_morpholog1.51167386
43MP0002933_joint_inflammation1.50136912
44MP0009278_abnormal_bone_marrow1.49165617
45MP0003077_abnormal_cell_cycle1.46760255
46MP0004742_abnormal_vestibular_system1.44617910
47MP0005025_abnormal_response_to1.44125291
48MP0010155_abnormal_intestine_physiology1.43254793
49MP0002653_abnormal_ependyma_morphology1.39373508
50MP0005076_abnormal_cell_differentiation1.37129583
51MP0002822_catalepsy1.36017752
52MP0009785_altered_susceptibility_to1.31374499
53MP0004130_abnormal_muscle_cell1.31106998
54MP0002095_abnormal_skin_pigmentation1.27056403
55MP0001879_abnormal_lymphatic_vessel1.26876175
56MP0003111_abnormal_nucleus_morphology1.26260347
57MP0001968_abnormal_touch/_nociception1.26220602
58MP0005646_abnormal_pituitary_gland1.24017997
59MP0003121_genomic_imprinting1.23268388
60MP0000015_abnormal_ear_pigmentation1.20459122
61MP0002019_abnormal_tumor_incidence1.19824557
62MP0004885_abnormal_endolymph1.18672872
63MP0000049_abnormal_middle_ear1.17577755
64MP0003880_abnormal_central_pattern1.11555856
65MP0002735_abnormal_chemical_nociception1.11200674
66MP0003635_abnormal_synaptic_transmissio1.08803805
67MP0000631_abnormal_neuroendocrine_gland1.06154317
68MP0004510_myositis1.05754734
69MP0009745_abnormal_behavioral_response1.05079652
70MP0010352_gastrointestinal_tract_polyps1.04626167
71MP0009333_abnormal_splenocyte_physiolog1.04075359
72MP0006292_abnormal_olfactory_placode1.03774054
73MP0005409_darkened_coat_color1.02283146
74MP0008058_abnormal_DNA_repair1.01189033
75MP0004947_skin_inflammation1.00711735
76MP0001845_abnormal_inflammatory_respons0.99514551
77MP0002928_abnormal_bile_duct0.98643732
78MP0002063_abnormal_learning/memory/cond0.97525432
79MP0000350_abnormal_cell_proliferation0.97222792
80MP0002272_abnormal_nervous_system0.97084674
81MP0005389_reproductive_system_phenotype0.96785162
82MP0000490_abnormal_crypts_of0.96565898
83MP0001440_abnormal_grooming_behavior0.94144167
84MP0002160_abnormal_reproductive_system0.93901237
85MP0008995_early_reproductive_senescence0.93677393
86MP0008877_abnormal_DNA_methylation0.93317242
87MP0002148_abnormal_hypersensitivity_rea0.92355421
88MP0005670_abnormal_white_adipose0.91930924
89MP0006276_abnormal_autonomic_nervous0.90865529
90MP0008961_abnormal_basal_metabolism0.89349962
91MP0005645_abnormal_hypothalamus_physiol0.86332335
92MP0003938_abnormal_ear_development0.85470128
93MP0008872_abnormal_physiological_respon0.84327845
94MP0002184_abnormal_innervation0.81939768
95MP0003315_abnormal_perineum_morphology0.81838570
96MP0001663_abnormal_digestive_system0.80636453
97MP0004924_abnormal_behavior0.79496853
98MP0005386_behavior/neurological_phenoty0.79496853
99MP0000470_abnormal_stomach_morphology0.79305725
100MP0001919_abnormal_reproductive_system0.78888298
101MP0000778_abnormal_nervous_system0.78446366
102MP0003119_abnormal_digestive_system0.77711384
103MP0003890_abnormal_embryonic-extraembry0.77579963
104MP0002419_abnormal_innate_immunity0.76659714
105MP0002837_dystrophic_cardiac_calcinosis0.74791624
106MP0000955_abnormal_spinal_cord0.74785218
107MP0002067_abnormal_sensory_capabilities0.74542889
108MP0001485_abnormal_pinna_reflex0.74506346
109MP0002009_preneoplasia0.73984106
110MP0004197_abnormal_fetal_growth/weight/0.72790518
111MP0002132_abnormal_respiratory_system0.72626500
112MP0004381_abnormal_hair_follicle0.71396709
113MP0003861_abnormal_nervous_system0.70664803
114MP0001486_abnormal_startle_reflex0.70664495
115MP0000377_abnormal_hair_follicle0.69716762
116MP0004859_abnormal_synaptic_plasticity0.69309829
117MP0002138_abnormal_hepatobiliary_system0.69166385
118MP0000733_abnormal_muscle_development0.68954144
119MP0000313_abnormal_cell_death0.68187440
120MP0002064_seizures0.68155115
121MP0001915_intracranial_hemorrhage0.67608037
122MP0006072_abnormal_retinal_apoptosis0.67243161
123MP0001853_heart_inflammation0.67108839
124MP0002572_abnormal_emotion/affect_behav0.66234890
125MP0001730_embryonic_growth_arrest0.65938210
126MP0008007_abnormal_cellular_replicative0.65352836
127MP0003091_abnormal_cell_migration0.63288969
128MP0005394_taste/olfaction_phenotype0.63231307
129MP0005499_abnormal_olfactory_system0.63231307
130MP0005397_hematopoietic_system_phenotyp0.61079002
131MP0001545_abnormal_hematopoietic_system0.61079002
132MP0005174_abnormal_tail_pigmentation0.61040513
133MP0001784_abnormal_fluid_regulation0.59404379
134MP0002751_abnormal_autonomic_nervous0.59120323
135MP0003943_abnormal_hepatobiliary_system0.58780313
136MP0001340_abnormal_eyelid_morphology0.58350755
137MP0002088_abnormal_embryonic_growth/wei0.58267480
138MP0003984_embryonic_growth_retardation0.58179357
139MP0005310_abnormal_salivary_gland0.57714519
140MP0005380_embryogenesis_phenotype0.56558914
141MP0001672_abnormal_embryogenesis/_devel0.56558914
142MP0002085_abnormal_embryonic_tissue0.56395442
143MP0008569_lethality_at_weaning0.55502364
144MP0008789_abnormal_olfactory_epithelium0.55336687
145MP0002925_abnormal_cardiovascular_devel0.54938955
146MP0002098_abnormal_vibrissa_morphology0.53998861
147MP0004134_abnormal_chest_morphology0.53803922
148MP0001286_abnormal_eye_development0.53266449

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)6.91730559
2B lymphocytopenia (HP:0010976)5.44070221
3Abnormality of B cell number (HP:0010975)5.44070221
4Verrucae (HP:0200043)5.33837712
5Papilloma (HP:0012740)5.33837712
6Panhypogammaglobulinemia (HP:0003139)5.27074411
7Thyroiditis (HP:0100646)4.72246906
8Cellulitis (HP:0100658)4.57778682
9Recurrent viral infections (HP:0004429)4.41200414
10Abnormality of the intervertebral disk (HP:0005108)4.37104736
11Severe combined immunodeficiency (HP:0004430)4.30356630
12Recurrent bronchitis (HP:0002837)4.09960619
13T lymphocytopenia (HP:0005403)4.08820931
14Abnormality of the fingertips (HP:0001211)4.00673281
15Abnormality of T cell number (HP:0011839)3.87846159
16Recurrent sinusitis (HP:0011108)3.74819141
17Combined immunodeficiency (HP:0005387)3.67925909
18Meningitis (HP:0001287)3.66121381
19Small epiphyses (HP:0010585)3.60351838
20Recurrent fungal infections (HP:0002841)3.56988573
21Erythroderma (HP:0001019)3.56752851
22IgG deficiency (HP:0004315)3.48195926
23Inflammation of the large intestine (HP:0002037)3.39439942
24Gastrointestinal stroma tumor (HP:0100723)3.33429694
25Gastrointestinal inflammation (HP:0004386)3.32204603
26Vertebral arch anomaly (HP:0008438)3.17504540
27Colitis (HP:0002583)3.16423912
28Hypoplasia of the thymus (HP:0000778)3.13628203
29Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)3.12005586
30Short 1st metacarpal (HP:0010034)3.12005586
31Abnormal delayed hypersensitivity skin test (HP:0002963)2.97125183
32Sepsis (HP:0100806)2.89261534
33Chronic mucocutaneous candidiasis (HP:0002728)2.87568057
34Recurrent cutaneous fungal infections (HP:0011370)2.87568057
35Long eyelashes (HP:0000527)2.86793233
36Lymphopenia (HP:0001888)2.84138122
37Chronic sinusitis (HP:0011109)2.79937066
38Cutis marmorata (HP:0000965)2.79691208
39Eosinophilia (HP:0001880)2.79562036
40IgM deficiency (HP:0002850)2.77054264
41Abnormality of T cells (HP:0002843)2.75665513
42Abnormality of cells of the lymphoid lineage (HP:0012140)2.73458751
43Osteomyelitis (HP:0002754)2.72065552
44Volvulus (HP:0002580)2.70756459
45Abnormality of the 1st metacarpal (HP:0010009)2.69328962
46Recurrent otitis media (HP:0000403)2.62958221
47IgA deficiency (HP:0002720)2.61345337
48Acute lymphatic leukemia (HP:0006721)2.52728832
49Chronic diarrhea (HP:0002028)2.46410267
50Recurrent pneumonia (HP:0006532)2.44221287
51Abnormality of eosinophils (HP:0001879)2.42543548
52Mitral stenosis (HP:0001718)2.42092159
53Short phalanx of the thumb (HP:0009660)2.36551245
54Chronic hepatic failure (HP:0100626)2.29921970
55Carpal bone hypoplasia (HP:0001498)2.21845491
56Granulocytopenia (HP:0001913)2.19161435
57Aqueductal stenosis (HP:0002410)2.18801084
58Short 4th metacarpal (HP:0010044)2.18732934
59Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.18732934
60Recurrent lower respiratory tract infections (HP:0002783)2.18706381
61Abnormal hair whorl (HP:0010721)2.15408246
62Tented upper lip vermilion (HP:0010804)2.13525918
63Limited elbow extension (HP:0001377)2.11204045
64Lymphoma (HP:0002665)2.11104726
65Viral hepatitis (HP:0006562)2.10995211
66Progressive cerebellar ataxia (HP:0002073)2.10927038
67Hypoplasia of the capital femoral epiphysis (HP:0003090)2.08042012
68Neoplasm of the adrenal cortex (HP:0100641)2.05284362
69Stomach cancer (HP:0012126)2.03792135
70Chronic otitis media (HP:0000389)2.02669281
71Bronchitis (HP:0012387)2.01506071
72Stomatitis (HP:0010280)2.00334445
73Vasculitis (HP:0002633)1.99808066
74Abnormality of the renal collecting system (HP:0004742)1.95069566
75Genetic anticipation (HP:0003743)1.93390002
76Emphysema (HP:0002097)1.93378830
77Abnormality of the columella (HP:0009929)1.92331583
78Arthropathy (HP:0003040)1.89391462
79Slow-growing hair (HP:0002217)1.89005017
80Abnormality of hair growth rate (HP:0011363)1.89005017
81Abnormality of the nasal septum (HP:0000419)1.88980398
82Hyperventilation (HP:0002883)1.88354520
83Flattened epiphyses (HP:0003071)1.87336738
84Mediastinal lymphadenopathy (HP:0100721)1.87008341
85Ectopic kidney (HP:0000086)1.86482389
86Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.84416889
87Heterotopia (HP:0002282)1.82398167
88Abnormality of DNA repair (HP:0003254)1.81561021
89Trigonocephaly (HP:0000243)1.81392176
90Thick eyebrow (HP:0000574)1.81004932
91Molar tooth sign on MRI (HP:0002419)1.79996104
92Abnormality of midbrain morphology (HP:0002418)1.79996104
93Stenosis of the external auditory canal (HP:0000402)1.79226161
94Basal cell carcinoma (HP:0002671)1.78272595
95Broad-based gait (HP:0002136)1.76634603
96Hypoproteinemia (HP:0003075)1.75470200
97Leukocytosis (HP:0001974)1.73854650
98Pancreatic cysts (HP:0001737)1.72896433
99Aplasia/Hypoplasia of the thymus (HP:0010515)1.71204069
100Midline defect of the nose (HP:0004122)1.70642493
101Focal motor seizures (HP:0011153)1.69945666
102Sparse scalp hair (HP:0002209)1.69904008
103Increased density of long bones (HP:0006392)1.69229644
104Supernumerary ribs (HP:0005815)1.68946220
105Ulnar bowing (HP:0003031)1.68247282
106Patellar aplasia (HP:0006443)1.67420154
107Abnormality of the prostate (HP:0008775)1.65911162
108Widely spaced teeth (HP:0000687)1.65795092
109Skin rash (HP:0000988)1.64311639
110Protruding tongue (HP:0010808)1.64169091
111Subacute progressive viral hepatitis (HP:0006572)1.64000940
112Congenital stationary night blindness (HP:0007642)1.63034811
113Abnormality of the thymus (HP:0000777)1.62750814
114Restrictive lung disease (HP:0002091)1.61918086
115Cortical dysplasia (HP:0002539)1.61426440
116Macroorchidism (HP:0000053)1.61105205
117Leukopenia (HP:0001882)1.60856434
118Abnormality of the 4th metacarpal (HP:0010012)1.59964110
119Sparse lateral eyebrow (HP:0005338)1.59629116
120Encephalitis (HP:0002383)1.57351328
121Febrile seizures (HP:0002373)1.57274111
122Prostate neoplasm (HP:0100787)1.55913069
123Proximal placement of thumb (HP:0009623)1.55909734
124Absent rod-and cone-mediated responses on ERG (HP:0007688)1.55894528
125Aplasia/Hypoplasia of the sternum (HP:0006714)1.55596317
126Aplasia/Hypoplasia of the patella (HP:0006498)1.55077739
127Abnormal number of incisors (HP:0011064)1.53507772
128Wide intermamillary distance (HP:0006610)1.52942664
129Aortic regurgitation (HP:0001659)1.52651515
130Agitation (HP:0000713)1.52530052
131Short philtrum (HP:0000322)1.52183343
1322-3 toe syndactyly (HP:0004691)1.51294002
133Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.51287591
134Duplicated collecting system (HP:0000081)1.49686207
135Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.49250028
136Truncal obesity (HP:0001956)1.48711750
137Clumsiness (HP:0002312)1.46915733
138Hypoplastic iliac wings (HP:0002866)1.46588964
139Nephronophthisis (HP:0000090)1.46409459
140Pendular nystagmus (HP:0012043)1.46328350
141Papilledema (HP:0001085)1.45016022
142Congenital sensorineural hearing impairment (HP:0008527)1.43596974
143Abnormality of male internal genitalia (HP:0000022)1.43394900
144Asplenia (HP:0001746)1.43262592
145Morphological abnormality of the middle ear (HP:0008609)1.42966026
146Elevated erythrocyte sedimentation rate (HP:0003565)1.42053482
147Dialeptic seizures (HP:0011146)1.41949586
148Hematochezia (HP:0002573)1.41908777
149Colon cancer (HP:0003003)1.40055164
150Bony spicule pigmentary retinopathy (HP:0007737)1.38047849
151Oligodactyly (hands) (HP:0001180)1.37854598
152True hermaphroditism (HP:0010459)1.36670515
153Synostosis of carpal bones (HP:0005048)1.35425453
154Cellular immunodeficiency (HP:0005374)1.35323065
155Excessive salivation (HP:0003781)1.35259260
156Renal cortical cysts (HP:0000803)1.31255075

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K106.64277108
2MAP4K14.25116167
3EEF2K3.24537962
4CASK2.83586898
5GRK62.80954079
6SIK32.74237483
7SIK22.67833619
8FRK2.34847513
9CDK122.28703944
10SYK1.94778765
11TAOK31.89731812
12BMPR1B1.80322789
13MAP3K131.74977729
14TXK1.74652159
15FGFR31.74253335
16BLK1.61919777
17JAK31.54978881
18CDK91.50203955
19ITK1.49567453
20NLK1.49168195
21BRD41.48200780
22STK101.46878516
23MAP3K91.46501563
24BTK1.43483707
25TLK11.38405916
26CSF1R1.38185702
27ZAP701.37023904
28PIK3CG1.35444937
29ERN11.34573958
30GRK11.34359408
31MAP3K141.32124391
32CLK11.29674904
33MARK21.28712618
34FGFR21.26885174
35MARK11.25809504
36MAP3K41.25186006
37MAPK131.23756178
38CAMK1G1.22576877
39EIF2AK31.19741295
40FES1.19649823
41PASK1.15996722
42MARK31.15584608
43HCK1.14327979
44CDK41.14199663
45MAP3K71.12547898
46ADRBK21.12217948
47CSNK1A1L1.11599126
48LYN1.10286977
49STK41.05333064
50PIM11.04239060
51FGFR41.03076245
52TYRO30.99407012
53LCK0.99377426
54STK110.96941590
55TAF10.95466483
56MAP2K20.94584682
57CSNK1G10.89457456
58SIK10.88756564
59NEK20.88366513
60PKN10.87856115
61CAMKK20.86108636
62CDC70.85971878
63MELK0.85915206
64CHUK0.85603565
65PRKCQ0.85336214
66SGK30.85034842
67TYK20.83254136
68SGK20.81671482
69RPS6KA60.80800982
70CSNK1G30.79710544
71HIPK20.79408559
72WNK10.79180637
73DYRK20.78400196
74MAP2K70.77034592
75PRKCH0.76983873
76CSK0.76973500
77CSNK1D0.76697121
78TGFBR10.75416909
79JAK10.73441250
80CAMKK10.73291737
81WNK30.71968490
82PINK10.71940670
83CDK80.71734727
84CHEK10.71389518
85NTRK20.71320248
86MAPK40.70913896
87NTRK30.70535094
88CSNK1G20.69144054
89RPS6KL10.68984669
90RPS6KC10.68984669
91TEC0.68510924
92CDK60.68443206
93IKBKB0.68363012
94CAMK40.67391369
95DYRK1B0.66858592
96MKNK20.65269128
97SRPK10.65226512
98MAPK70.64454700
99DYRK30.63863471
100CHEK20.62122807
101MAP4K20.60662868
102EPHA30.60322399
103ATR0.58585252
104IKBKE0.57983319
105RIPK40.57867819
106ICK0.56843566
107PRKD20.56725688
108RPS6KA40.56470718
109DYRK1A0.54964219
110NUAK10.54019050
111PNCK0.53064158
112MAPK120.52643585
113SGK10.52639298
114ZAK0.52342869
115LRRK20.52040032
116KSR10.50611443
117TNK20.49971361
118TAOK10.49415717
119TNIK0.49311537
120UHMK10.49222705
121RPS6KA50.47695518
122CDK30.46117106
123PRKD10.45952104
124RPS6KB20.45711076
125MAPK110.45580858
126ALK0.45482876
127PAK30.44373954
128FYN0.43235444
129CAMK10.40306571
130CDK20.40024402
131PRPF4B0.39580399
132TRIB30.39180102
133CAMK1D0.38653807
134CDK50.37555063
135SGK4940.37039106
136SGK2230.37039106
137MAPK30.36503007
138IRAK40.36112499
139INSR0.36104174
140ERBB30.35766583

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.27661902
2B cell receptor signaling pathway_Homo sapiens_hsa046623.76611131
3Non-homologous end-joining_Homo sapiens_hsa034502.62171090
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.46612719
5T cell receptor signaling pathway_Homo sapiens_hsa046602.29673573
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.19297034
7Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.90984278
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.82771609
9Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.82286279
10Asthma_Homo sapiens_hsa053101.81716252
11Nicotine addiction_Homo sapiens_hsa050331.78486564
12Phototransduction_Homo sapiens_hsa047441.70813185
13Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.70397680
14Chronic myeloid leukemia_Homo sapiens_hsa052201.70130031
15Measles_Homo sapiens_hsa051621.68388980
16Osteoclast differentiation_Homo sapiens_hsa043801.57919929
17Systemic lupus erythematosus_Homo sapiens_hsa053221.51047850
18Transcriptional misregulation in cancer_Homo sapiens_hsa052021.48223598
19Pancreatic cancer_Homo sapiens_hsa052121.46721750
20Hematopoietic cell lineage_Homo sapiens_hsa046401.43993478
21Base excision repair_Homo sapiens_hsa034101.43892550
22Colorectal cancer_Homo sapiens_hsa052101.43169834
23Dorso-ventral axis formation_Homo sapiens_hsa043201.42180922
24Viral carcinogenesis_Homo sapiens_hsa052031.38556527
25Viral myocarditis_Homo sapiens_hsa054161.36342367
26Jak-STAT signaling pathway_Homo sapiens_hsa046301.34020145
27Non-small cell lung cancer_Homo sapiens_hsa052231.32458899
28mRNA surveillance pathway_Homo sapiens_hsa030151.32451108
29Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.30725023
30Acute myeloid leukemia_Homo sapiens_hsa052211.28399057
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.27570545
32HTLV-I infection_Homo sapiens_hsa051661.26491683
33Herpes simplex infection_Homo sapiens_hsa051681.25970840
34Hepatitis B_Homo sapiens_hsa051611.25147037
35MicroRNAs in cancer_Homo sapiens_hsa052061.23846311
36Morphine addiction_Homo sapiens_hsa050321.21755503
37Epstein-Barr virus infection_Homo sapiens_hsa051691.16229777
38Chemokine signaling pathway_Homo sapiens_hsa040621.12892031
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.10533897
40Endometrial cancer_Homo sapiens_hsa052131.10180502
41Spliceosome_Homo sapiens_hsa030401.10060805
42Olfactory transduction_Homo sapiens_hsa047401.08646182
43Taste transduction_Homo sapiens_hsa047421.06826456
44RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.06013652
45Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.05798789
46Allograft rejection_Homo sapiens_hsa053301.03722822
47Cell cycle_Homo sapiens_hsa041101.03713213
48Leishmaniasis_Homo sapiens_hsa051401.03250408
49Prostate cancer_Homo sapiens_hsa052151.00904566
50Alcoholism_Homo sapiens_hsa050340.99639606
51Lysine degradation_Homo sapiens_hsa003100.98909736
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96440112
53Cholinergic synapse_Homo sapiens_hsa047250.91295573
54FoxO signaling pathway_Homo sapiens_hsa040680.91237263
55Renal cell carcinoma_Homo sapiens_hsa052110.90821699
56Toxoplasmosis_Homo sapiens_hsa051450.89971454
57Notch signaling pathway_Homo sapiens_hsa043300.89814762
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.88948160
59Thyroid hormone signaling pathway_Homo sapiens_hsa049190.88553999
60Fanconi anemia pathway_Homo sapiens_hsa034600.88100619
61Small cell lung cancer_Homo sapiens_hsa052220.87541457
62Prolactin signaling pathway_Homo sapiens_hsa049170.84795172
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.84746409
64Glioma_Homo sapiens_hsa052140.84502992
65Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.83297856
66MAPK signaling pathway_Homo sapiens_hsa040100.82848763
67Toll-like receptor signaling pathway_Homo sapiens_hsa046200.82607987
68Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81556397
69Basal transcription factors_Homo sapiens_hsa030220.80700082
70Influenza A_Homo sapiens_hsa051640.78025107
71Shigellosis_Homo sapiens_hsa051310.77407184
72ErbB signaling pathway_Homo sapiens_hsa040120.77322571
73Autoimmune thyroid disease_Homo sapiens_hsa053200.77172263
74Antigen processing and presentation_Homo sapiens_hsa046120.76998768
75Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.76436370
76Mismatch repair_Homo sapiens_hsa034300.76366370
77AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.76043322
78Linoleic acid metabolism_Homo sapiens_hsa005910.75052027
79Platelet activation_Homo sapiens_hsa046110.74885091
80Choline metabolism in cancer_Homo sapiens_hsa052310.74814605
81Apoptosis_Homo sapiens_hsa042100.74622385
82Axon guidance_Homo sapiens_hsa043600.73706765
83Glutamatergic synapse_Homo sapiens_hsa047240.73604616
84Long-term potentiation_Homo sapiens_hsa047200.73079349
85mTOR signaling pathway_Homo sapiens_hsa041500.72621773
86Circadian entrainment_Homo sapiens_hsa047130.72078147
87Tuberculosis_Homo sapiens_hsa051520.70265965
88Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.70148185
89RNA degradation_Homo sapiens_hsa030180.69968673
90TNF signaling pathway_Homo sapiens_hsa046680.68758409
91Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.68203534
92RNA polymerase_Homo sapiens_hsa030200.67462389
93Dopaminergic synapse_Homo sapiens_hsa047280.67009033
94VEGF signaling pathway_Homo sapiens_hsa043700.66498526
95Leukocyte transendothelial migration_Homo sapiens_hsa046700.66384517
96GABAergic synapse_Homo sapiens_hsa047270.65213169
97Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65091379
98Wnt signaling pathway_Homo sapiens_hsa043100.63543425
99Pathways in cancer_Homo sapiens_hsa052000.62822295
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.62806518
101Oxytocin signaling pathway_Homo sapiens_hsa049210.62584477
102Hedgehog signaling pathway_Homo sapiens_hsa043400.62371883
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.62136371
104DNA replication_Homo sapiens_hsa030300.60722693
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.60104799
106Amphetamine addiction_Homo sapiens_hsa050310.59430282
107Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58374829
108Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.58335916
109p53 signaling pathway_Homo sapiens_hsa041150.57748410
110Hepatitis C_Homo sapiens_hsa051600.57596792
111Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57085228
112Graft-versus-host disease_Homo sapiens_hsa053320.56693881
113Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55789458
114RNA transport_Homo sapiens_hsa030130.55730217
115Calcium signaling pathway_Homo sapiens_hsa040200.53801838
116Basal cell carcinoma_Homo sapiens_hsa052170.53426667
117Caffeine metabolism_Homo sapiens_hsa002320.52897915
118Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52479068
119Cocaine addiction_Homo sapiens_hsa050300.52474438
120Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.50901051
121Homologous recombination_Homo sapiens_hsa034400.49830936
122Serotonergic synapse_Homo sapiens_hsa047260.49762968
123Type I diabetes mellitus_Homo sapiens_hsa049400.49663322
124cAMP signaling pathway_Homo sapiens_hsa040240.48916782
125Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46018062
126Long-term depression_Homo sapiens_hsa047300.45293760
127Insulin resistance_Homo sapiens_hsa049310.43861482
128Sphingolipid signaling pathway_Homo sapiens_hsa040710.43534167
129Endocytosis_Homo sapiens_hsa041440.42562761
130Maturity onset diabetes of the young_Homo sapiens_hsa049500.41628900
131Inositol phosphate metabolism_Homo sapiens_hsa005620.41430285
132Type II diabetes mellitus_Homo sapiens_hsa049300.39514006
133Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39285556
134Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39237405
135Adherens junction_Homo sapiens_hsa045200.38391381
136Ras signaling pathway_Homo sapiens_hsa040140.36889753

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