B3GNT7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)7.74538586
2embryonic process involved in female pregnancy (GO:0060136)6.51298404
3transcription from mitochondrial promoter (GO:0006390)6.15355656
4replication fork processing (GO:0031297)5.81666516
5establishment of apical/basal cell polarity (GO:0035089)5.69735683
6proline metabolic process (GO:0006560)5.69446062
7somatic diversification of immune receptors via somatic mutation (GO:0002566)5.25879899
8somatic hypermutation of immunoglobulin genes (GO:0016446)5.25879899
9regulation of gene silencing by RNA (GO:0060966)5.15889960
10regulation of posttranscriptional gene silencing (GO:0060147)5.15889960
11regulation of gene silencing by miRNA (GO:0060964)5.15889960
12maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)5.07384244
13DNA deamination (GO:0045006)5.06882754
14regulation of integrin activation (GO:0033623)5.03676899
15positive regulation of protein homooligomerization (GO:0032464)4.89360564
16establishment or maintenance of monopolar cell polarity (GO:0061339)4.87509999
17establishment of monopolar cell polarity (GO:0061162)4.87509999
18formation of translation preinitiation complex (GO:0001731)4.61926256
19regulation of translational fidelity (GO:0006450)4.61350738
20mitochondrial DNA metabolic process (GO:0032042)4.58081083
21mitotic G1 DNA damage checkpoint (GO:0031571)4.30767329
22trophectodermal cell differentiation (GO:0001829)4.23468883
23calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.21841391
24regulation of protein homooligomerization (GO:0032462)4.21639267
25water-soluble vitamin biosynthetic process (GO:0042364)4.21140821
26histone H4-K12 acetylation (GO:0043983)4.18021510
27DNA strand renaturation (GO:0000733)4.16935998
28oxidative demethylation (GO:0070989)4.09329964
29embryonic placenta development (GO:0001892)4.01191485
30nodal signaling pathway (GO:0038092)3.97907246
31viral mRNA export from host cell nucleus (GO:0046784)3.92733514
32transcytosis (GO:0045056)3.92679915
33mitotic G1/S transition checkpoint (GO:0044819)3.91828693
34telomere maintenance via semi-conservative replication (GO:0032201)3.88369022
35synapsis (GO:0007129)3.87929254
36spliceosomal tri-snRNP complex assembly (GO:0000244)3.87612727
37RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.85288008
38negative regulation of telomerase activity (GO:0051974)3.76924304
39negative regulation of DNA-dependent DNA replication (GO:2000104)3.76266130
40mRNA cleavage (GO:0006379)3.74336055
41G1 DNA damage checkpoint (GO:0044783)3.72293827
42regulation of mesoderm development (GO:2000380)3.70101197
43negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.68195588
44establishment of protein localization to mitochondrial membrane (GO:0090151)3.66663857
45positive regulation of mitotic sister chromatid separation (GO:1901970)3.65366496
46positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.65366496
47positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.65366496
48base-excision repair (GO:0006284)3.64604342
49pre-miRNA processing (GO:0031054)3.64006038
50determination of adult lifespan (GO:0008340)3.63428154
51regulation of sister chromatid cohesion (GO:0007063)3.63163199
52anterior/posterior axis specification, embryo (GO:0008595)3.62379702
53dosage compensation (GO:0007549)3.60181277
54DNA strand elongation involved in DNA replication (GO:0006271)3.58700534
55female gonad development (GO:0008585)3.54771937
56negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.52174833
57cobalamin metabolic process (GO:0009235)3.50473023
58apoptotic process involved in morphogenesis (GO:0060561)3.48056830
59nucleotide-excision repair, DNA gap filling (GO:0006297)3.45893127
60poly(A)+ mRNA export from nucleus (GO:0016973)3.44820603
61chromatin remodeling at centromere (GO:0031055)3.44603459
62DNA replication checkpoint (GO:0000076)3.44060524
63regulation of helicase activity (GO:0051095)3.43626987
64regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.42838060
65regulation of mitotic spindle checkpoint (GO:1903504)3.42838060
66regulation of hippo signaling (GO:0035330)3.42547135
67intestinal epithelial cell development (GO:0060576)3.39404349
68mitotic sister chromatid segregation (GO:0000070)3.38336742
69negative regulation of JAK-STAT cascade (GO:0046426)3.37031364
70negative regulation of cell cycle arrest (GO:0071157)3.36273226
71DNA strand elongation (GO:0022616)3.36016291
72sulfation (GO:0051923)3.34124430
73regulation of double-strand break repair via homologous recombination (GO:0010569)3.32349793
74negative regulation of mRNA processing (GO:0050686)3.31402222
75kidney morphogenesis (GO:0060993)3.30238102
76histone exchange (GO:0043486)3.29262601
77regulation of RNA export from nucleus (GO:0046831)3.25985610
78positive regulation of protein oligomerization (GO:0032461)3.25916106
79positive regulation of chromosome segregation (GO:0051984)3.25108540
80mitochondrial RNA metabolic process (GO:0000959)3.24428366
81regulation of meiosis I (GO:0060631)3.23367678
82embryonic camera-type eye development (GO:0031076)3.23215698
83somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.22576320
84somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.22576320
85isotype switching (GO:0045190)3.22576320
86telomere maintenance via recombination (GO:0000722)3.21476081
87DNA integration (GO:0015074)3.20927093
88meiotic chromosome segregation (GO:0045132)3.20602646
89CENP-A containing nucleosome assembly (GO:0034080)3.19687023
90termination of RNA polymerase II transcription (GO:0006369)3.17355980
91respiratory chain complex IV assembly (GO:0008535)3.16019970
92GDP-mannose metabolic process (GO:0019673)3.15504145
93negative regulation of gene silencing (GO:0060969)3.14933975
94transepithelial transport (GO:0070633)3.14742619
95regulation of telomerase activity (GO:0051972)3.13239293
96axonemal dynein complex assembly (GO:0070286)3.10609100
97double-strand break repair via nonhomologous end joining (GO:0006303)3.10544774
98non-recombinational repair (GO:0000726)3.10544774
99regulation of double-strand break repair (GO:2000779)3.09318758
100proteasome assembly (GO:0043248)3.09313221
101fucose catabolic process (GO:0019317)3.07877169
102L-fucose metabolic process (GO:0042354)3.07877169
103L-fucose catabolic process (GO:0042355)3.07877169
104heterochromatin organization (GO:0070828)3.07428017
105mitotic nuclear envelope disassembly (GO:0007077)3.07254304
106kinetochore assembly (GO:0051382)3.03629191
107DNA double-strand break processing (GO:0000729)3.03559859
108lung-associated mesenchyme development (GO:0060484)3.03546778
109labyrinthine layer development (GO:0060711)3.03168117
110maturation of 5.8S rRNA (GO:0000460)3.02893079
111negative regulation of Ras GTPase activity (GO:0034261)3.02114426
112positive regulation by host of viral transcription (GO:0043923)3.02010623
113regulation of nuclear cell cycle DNA replication (GO:0033262)3.00809629
114vitamin transmembrane transport (GO:0035461)3.00676156
115negative regulation of RNA splicing (GO:0033119)2.99845641
116regulation of DNA damage checkpoint (GO:2000001)2.97988560
117positive regulation of SMAD protein import into nucleus (GO:0060391)2.97263953
118positive regulation of prostaglandin secretion (GO:0032308)2.95844396
119histone arginine methylation (GO:0034969)2.95810646
120base-excision repair, AP site formation (GO:0006285)2.94530814
121negative regulation of fatty acid biosynthetic process (GO:0045717)2.94245677
122uronic acid metabolic process (GO:0006063)2.93385057
123glucuronate metabolic process (GO:0019585)2.93385057
124intracellular estrogen receptor signaling pathway (GO:0030520)2.91182609
125DNA catabolic process, exonucleolytic (GO:0000738)2.91016840
126DNA topological change (GO:0006265)2.89579925
127telomere maintenance via telomere lengthening (GO:0010833)2.88291688
128ribosome biogenesis (GO:0042254)2.87711341
129negative regulation of androgen receptor signaling pathway (GO:0060766)2.87299352
130regulation of protein oligomerization (GO:0032459)2.86222551
131chaperone-mediated protein transport (GO:0072321)2.85933839
132mitotic recombination (GO:0006312)2.84857743
133face development (GO:0060324)2.84778832
134glutamine family amino acid biosynthetic process (GO:0009084)2.84136378
135nuclear envelope disassembly (GO:0051081)2.84053614
136membrane disassembly (GO:0030397)2.84053614
137sister chromatid segregation (GO:0000819)2.82648669
138cellular response to ATP (GO:0071318)2.82142041
139ncRNA catabolic process (GO:0034661)2.81595175
140positive regulation of glycoprotein biosynthetic process (GO:0010560)2.80934310
141vitamin biosynthetic process (GO:0009110)2.79584344
142cell fate commitment involved in formation of primary germ layer (GO:0060795)2.78409880
143negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.77941243
144rRNA catabolic process (GO:0016075)2.77693370
145negative regulation of mRNA metabolic process (GO:1903312)2.77537699
146IMP biosynthetic process (GO:0006188)2.76823972
147exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.74565686
148regulation of guanylate cyclase activity (GO:0031282)2.72722416
149DNA replication-dependent nucleosome assembly (GO:0006335)2.71979840
150DNA replication-dependent nucleosome organization (GO:0034723)2.71979840
151regulation of chromatin silencing (GO:0031935)2.71120661
152lysine catabolic process (GO:0006554)2.69909968
153lysine metabolic process (GO:0006553)2.69909968
154cellular glucuronidation (GO:0052695)2.69028634
155branching involved in labyrinthine layer morphogenesis (GO:0060670)2.67776875
156L-ascorbic acid metabolic process (GO:0019852)2.65727483
157sulfate transmembrane transport (GO:1902358)2.64348868
158telomere maintenance via telomerase (GO:0007004)2.62202258
159nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.61897186
160epithelial cilium movement (GO:0003351)2.60509247
161somatic recombination of immunoglobulin gene segments (GO:0016447)2.60207292
162male meiosis I (GO:0007141)2.60167816
163signal transduction involved in regulation of gene expression (GO:0023019)2.59749853
164lateral sprouting from an epithelium (GO:0060601)2.59556324
165hyperosmotic salinity response (GO:0042538)2.58007429
166cytochrome complex assembly (GO:0017004)2.57792131
167regulation of cell fate commitment (GO:0010453)2.57052824
168positive regulation of respiratory burst (GO:0060267)2.54989155
169protein neddylation (GO:0045116)2.54440560
170axoneme assembly (GO:0035082)2.53866216
171termination of RNA polymerase III transcription (GO:0006386)2.51816086
172transcription elongation from RNA polymerase III promoter (GO:0006385)2.51816086
173glutathione derivative biosynthetic process (GO:1901687)2.51812898
174glutathione derivative metabolic process (GO:1901685)2.51812898
175negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.51607065
176piRNA metabolic process (GO:0034587)2.51452194
177response to X-ray (GO:0010165)2.50881622
178cell migration involved in gastrulation (GO:0042074)2.49545034
179intra-S DNA damage checkpoint (GO:0031573)2.49366228
180male meiosis (GO:0007140)2.48787452
181cilium movement (GO:0003341)2.47778106
182DNA methylation involved in gamete generation (GO:0043046)2.44874997
183thyroid hormone metabolic process (GO:0042403)2.44705397
184regulation of DNA endoreduplication (GO:0032875)2.44309153
185response to UV-C (GO:0010225)2.43234490
186regulation of telomere maintenance via telomerase (GO:0032210)2.43136515
187somatic diversification of immunoglobulins (GO:0016445)2.43071766

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.70963017
2KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.80199046
3KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.80199046
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.80199046
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.74424721
6* SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.32662764
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.24701235
8MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.02183020
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.87174548
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.78731287
11ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.77461333
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.76433730
13* FLI1_27457419_Chip-Seq_LIVER_Mouse2.74903418
14POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.68466343
15* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.64409747
16ZNF274_21170338_ChIP-Seq_K562_Hela2.55912199
17SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.49920560
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.48676075
19* NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.42535145
20* NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.38095000
21SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.37780648
22* VDR_22108803_ChIP-Seq_LS180_Human2.32748489
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.26425973
24TCF3_18692474_ChIP-Seq_MEFs_Mouse2.25557765
25* KLF4_18358816_ChIP-ChIP_MESCs_Mouse2.19344934
26* PCGF2_27294783_Chip-Seq_ESCs_Mouse2.18519399
27E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.18405543
28RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.17398665
29* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.12774990
30STAT3_1855785_ChIP-Seq_MESCs_Mouse2.12388890
31* TCF3_18692474_ChIP-Seq_MESCs_Mouse2.11698906
32ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.10339638
33* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.10082613
34NANOG_18555785_ChIP-Seq_MESCs_Mouse2.10067175
35POU5F1_16153702_ChIP-ChIP_HESCs_Human2.09502960
36FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.06481956
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.97706203
38NANOG_16153702_ChIP-ChIP_HESCs_Human1.96986075
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.91526669
40* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.90406993
41IRF1_19129219_ChIP-ChIP_H3396_Human1.87949959
42HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.85335971
43E2F4_17652178_ChIP-ChIP_JURKAT_Human1.80943593
44* POU5F1_16518401_ChIP-PET_MESCs_Mouse1.79562372
45* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.78725871
46VDR_21846776_ChIP-Seq_THP-1_Human1.77589091
47DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.74888603
48POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.74073874
49HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.71558983
50MYC_22102868_ChIP-Seq_BL_Human1.69969225
51P300_19829295_ChIP-Seq_ESCs_Human1.66759362
52EGR1_23403033_ChIP-Seq_LIVER_Mouse1.66265634
53NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.63678570
54POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.62038796
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.60423200
56NANOG_21062744_ChIP-ChIP_HESCs_Human1.58920881
57* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.58087344
58NELFA_20434984_ChIP-Seq_ESCs_Mouse1.57511185
59EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.57426747
60* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.54781762
61AUTS2_25519132_ChIP-Seq_293T-REX_Human1.53083438
62* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.52769572
63GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.52248774
64TP63_17297297_ChIP-ChIP_HaCaT_Human1.51549113
65MYC_18940864_ChIP-ChIP_HL60_Human1.51385342
66CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.50621891
67NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.50160875
68EWS_26573619_Chip-Seq_HEK293_Human1.47791080
69GATA4_25053715_ChIP-Seq_YYC3_Human1.45758415
70FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.45685435
71MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.44975927
72ESR1_15608294_ChIP-ChIP_MCF-7_Human1.43469026
73SOX2_18555785_ChIP-Seq_MESCs_Mouse1.43358028
74SOX2_18692474_ChIP-Seq_MEFs_Mouse1.43111507
75* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.42783824
76* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.42332575
77FOXA1_27270436_Chip-Seq_PROSTATE_Human1.42118769
78FOXA1_25329375_ChIP-Seq_VCAP_Human1.42118769
79ZNF263_19887448_ChIP-Seq_K562_Human1.41247841
80SOX2_16153702_ChIP-ChIP_HESCs_Human1.41205669
81JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.37730827
82OCT4_18692474_ChIP-Seq_MEFs_Mouse1.37679550
83* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.37563618
84* CDX2_22108803_ChIP-Seq_LS180_Human1.37150735
85* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.35871507
86TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.35365331
87SOX2_19829295_ChIP-Seq_ESCs_Human1.35064641
88NANOG_19829295_ChIP-Seq_ESCs_Human1.35064641
89ETS1_20019798_ChIP-Seq_JURKAT_Human1.34757239
90XRN2_22483619_ChIP-Seq_HELA_Human1.34524252
91* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.34139069
92SALL1_21062744_ChIP-ChIP_HESCs_Human1.33269713
93YY1_21170310_ChIP-Seq_MESCs_Mouse1.32536786
94FOXP3_21729870_ChIP-Seq_TREG_Human1.30650504
95VDR_23849224_ChIP-Seq_CD4+_Human1.29317430
96* NFE2_27457419_Chip-Seq_LIVER_Mouse1.28256100
97TCF4_22108803_ChIP-Seq_LS180_Human1.27120665
98NANOG_18692474_ChIP-Seq_MEFs_Mouse1.26690743
99GATA1_26923725_Chip-Seq_HPCs_Mouse1.26286359
100FOXA1_21572438_ChIP-Seq_LNCaP_Human1.26188128
101THAP11_20581084_ChIP-Seq_MESCs_Mouse1.23983540
102CREB1_15753290_ChIP-ChIP_HEK293T_Human1.23954382
103CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.22950693
104AR_20517297_ChIP-Seq_VCAP_Human1.22801389
105RACK7_27058665_Chip-Seq_MCF-7_Human1.21554212
106CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.19945770
107ZFP281_18757296_ChIP-ChIP_E14_Mouse1.19434953
108NANOG_20526341_ChIP-Seq_ESCs_Human1.19172668
109LXR_22292898_ChIP-Seq_THP-1_Human1.18737677
110RBPJ_21746931_ChIP-Seq_IB4_Human1.18049644
111E2F1_21310950_ChIP-Seq_MCF-7_Human1.17949083
112GABP_19822575_ChIP-Seq_HepG2_Human1.17050468
113KDM5A_27292631_Chip-Seq_BREAST_Human1.16961821
114HOXB7_26014856_ChIP-Seq_BT474_Human1.16805696
115* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.16798583
116KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.15428329
117BCAT_22108803_ChIP-Seq_LS180_Human1.15178181
118IGF1R_20145208_ChIP-Seq_DFB_Human1.14358030
119GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.14320367
120* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.13490498
121* EZH2_27294783_Chip-Seq_NPCs_Mouse1.12445203
122DCP1A_22483619_ChIP-Seq_HELA_Human1.11896631
123NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.11832451
124* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.11699420
125* PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.11047578
126ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11016971
127* SMAD4_21741376_ChIP-Seq_EPCs_Human1.10132598
128TTF2_22483619_ChIP-Seq_HELA_Human1.09954244
129ETV1_20927104_ChIP-Seq_GIST48_Human1.09469335
130* KAP1_27257070_Chip-Seq_ESCs_Mouse1.08777491
131TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08670786
132NCOR_22424771_ChIP-Seq_293T_Human1.07617813
133PHF8_20622853_ChIP-Seq_HELA_Human1.07348704
134* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06873449
135* PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.06870199
136* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.06670114
137ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.06373236
138SMAD3_21741376_ChIP-Seq_HESCs_Human1.05662436
139TP53_22573176_ChIP-Seq_HFKS_Human1.05164806
140EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04964060
141PU.1_20513432_ChIP-Seq_Bcells_Mouse1.04774643
142* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.04556351
143CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.04346701
144KAP1_22055183_ChIP-Seq_ESCs_Mouse1.03673994
145KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03431073
146HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.03112514
147NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03045620
148FUS_26573619_Chip-Seq_HEK293_Human1.02882464
149CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.02211902
150HIF1A_21447827_ChIP-Seq_MCF-7_Human1.01222156
151TFEB_21752829_ChIP-Seq_HELA_Human1.01001622
152CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00988462
153ELK1_19687146_ChIP-ChIP_HELA_Human1.00739810
154SRF_21415370_ChIP-Seq_HL-1_Mouse1.00448730
155AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99884546
156AR_21909140_ChIP-Seq_LNCAP_Human0.99661077
157TET1_21451524_ChIP-Seq_MESCs_Mouse0.99204485
158SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99000845
159BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98074993
160RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.97965494
161EST1_17652178_ChIP-ChIP_JURKAT_Human0.97777064
162GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.96472095
163FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.96350529
164CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95690325
165DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.95661783
166STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.95622695
167ESR1_21235772_ChIP-Seq_MCF-7_Human0.94957675
168* ELK3_25401928_ChIP-Seq_HUVEC_Human0.94810517
169EGR1_19374776_ChIP-ChIP_THP-1_Human0.94540928
170TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94071742
171ZFP57_27257070_Chip-Seq_ESCs_Mouse0.94053225
172ERG_21242973_ChIP-ChIP_JURKAT_Human0.93218457
173FOXH1_21741376_ChIP-Seq_EPCs_Human0.93212071
174SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92640267
175CDX2_20551321_ChIP-Seq_CACO-2_Human0.91468230

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.38344870
2MP0002254_reproductive_system_inflammat3.84716997
3MP0004957_abnormal_blastocyst_morpholog3.26162156
4MP0009278_abnormal_bone_marrow3.14096956
5MP0010352_gastrointestinal_tract_polyps3.06841191
6MP0010094_abnormal_chromosome_stability2.97476185
7MP0010030_abnormal_orbit_morphology2.87793267
8MP0002102_abnormal_ear_morphology2.84857770
9MP0003693_abnormal_embryo_hatching2.83523474
10MP0003195_calcinosis2.81673387
11MP0002138_abnormal_hepatobiliary_system2.78454919
12MP0005360_urolithiasis2.72962570
13MP0003111_abnormal_nucleus_morphology2.63319203
14MP0004264_abnormal_extraembryonic_tissu2.57125330
15MP0004133_heterotaxia2.51134113
16MP0003890_abnormal_embryonic-extraembry2.48940108
17MP0002653_abnormal_ependyma_morphology2.40899789
18MP0003283_abnormal_digestive_organ2.33465274
19MP0002139_abnormal_hepatobiliary_system2.29841879
20MP0005076_abnormal_cell_differentiation2.24104698
21MP0003077_abnormal_cell_cycle2.21097073
22MP0004233_abnormal_muscle_weight2.20021019
23MP0001666_abnormal_nutrient_absorption2.17262051
24MP0003119_abnormal_digestive_system2.15066626
25MP0000490_abnormal_crypts_of2.09883413
26MP0005171_absent_coat_pigmentation2.08343572
27MP0005377_hearing/vestibular/ear_phenot2.05015453
28MP0003878_abnormal_ear_physiology2.05015453
29MP0008875_abnormal_xenobiotic_pharmacok2.02542857
30MP0002086_abnormal_extraembryonic_tissu2.02170431
31MP0001485_abnormal_pinna_reflex2.00820793
32MP0008058_abnormal_DNA_repair1.97668038
33MP0004019_abnormal_vitamin_homeostasis1.96786716
34MP0001188_hyperpigmentation1.95503633
35MP0002009_preneoplasia1.94696503
36MP0002084_abnormal_developmental_patter1.94072903
37MP0005365_abnormal_bile_salt1.89260798
38MP0002876_abnormal_thyroid_physiology1.87666261
39MP0001730_embryonic_growth_arrest1.86992381
40MP0001697_abnormal_embryo_size1.86734524
41MP0002085_abnormal_embryonic_tissue1.85329793
42MP0000350_abnormal_cell_proliferation1.84335787
43MP0003786_premature_aging1.83690992
44MP0008932_abnormal_embryonic_tissue1.83291744
45MP0005085_abnormal_gallbladder_physiolo1.83184960
46MP0004197_abnormal_fetal_growth/weight/1.78001084
47MP0001672_abnormal_embryogenesis/_devel1.77776056
48MP0005380_embryogenesis_phenotype1.77776056
49MP0008995_early_reproductive_senescence1.74293262
50MP0006292_abnormal_olfactory_placode1.73332357
51MP0003453_abnormal_keratinocyte_physiol1.70430589
52MP0001545_abnormal_hematopoietic_system1.65811816
53MP0005397_hematopoietic_system_phenotyp1.65811816
54MP0001293_anophthalmia1.64673907
55MP0008872_abnormal_physiological_respon1.63770864
56MP0003705_abnormal_hypodermis_morpholog1.59346299
57MP0003567_abnormal_fetal_cardiomyocyte1.59020995
58MP0002277_abnormal_respiratory_mucosa1.57953548
59MP0008877_abnormal_DNA_methylation1.49934154
60MP0010307_abnormal_tumor_latency1.49313912
61MP0004782_abnormal_surfactant_physiolog1.49039328
62MP0004147_increased_porphyrin_level1.48641538
63MP0000462_abnormal_digestive_system1.48014602
64MP0003984_embryonic_growth_retardation1.45917516
65MP0001764_abnormal_homeostasis1.42534522
66MP0002088_abnormal_embryonic_growth/wei1.41734055
67MP0002249_abnormal_larynx_morphology1.40970440
68MP0002080_prenatal_lethality1.39641068
69MP0002796_impaired_skin_barrier1.37903236
70MP0004043_abnormal_pH_regulation1.36094777
71MP0005332_abnormal_amino_acid1.36041450
72MP0005670_abnormal_white_adipose1.35090799
73MP0000516_abnormal_urinary_system1.33822589
74MP0005367_renal/urinary_system_phenotyp1.33822589
75MP0000470_abnormal_stomach_morphology1.32730147
76MP0003937_abnormal_limbs/digits/tail_de1.31654194
77MP0003941_abnormal_skin_development1.30903907
78MP0010234_abnormal_vibrissa_follicle1.29078695
79MP0002111_abnormal_tail_morphology1.25362446
80MP0005174_abnormal_tail_pigmentation1.23348339
81MP0004885_abnormal_endolymph1.22960144
82MP0003566_abnormal_cell_adhesion1.22864413
83MP0000678_abnormal_parathyroid_gland1.22778959
84MP0006072_abnormal_retinal_apoptosis1.22082968
85MP0003718_maternal_effect1.20615323
86MP0003806_abnormal_nucleotide_metabolis1.17297711
87MP0000477_abnormal_intestine_morphology1.16007355
88MP0002160_abnormal_reproductive_system1.14650443
89MP0000049_abnormal_middle_ear1.14297489
90MP0002019_abnormal_tumor_incidence1.14131792
91MP0005501_abnormal_skin_physiology1.11921936
92MP0005636_abnormal_mineral_homeostasis1.11304555
93MP0003183_abnormal_peptide_metabolism1.09084529
94MP0009053_abnormal_anal_canal1.08828885
95MP0002282_abnormal_trachea_morphology1.07966007
96MP0003646_muscle_fatigue1.07473995
97MP0000371_diluted_coat_color1.06500371
98MP0001664_abnormal_digestion1.05586496
99MP0001765_abnormal_ion_homeostasis1.05225592
100MP0001661_extended_life_span1.03827723
101MP0000537_abnormal_urethra_morphology1.02752935
102MP0001929_abnormal_gametogenesis1.01958636
103MP0003011_delayed_dark_adaptation1.01087523
104MP0000313_abnormal_cell_death0.99176053
105MP0005389_reproductive_system_phenotype0.98931288
106MP0001849_ear_inflammation0.97700620
107MP0006036_abnormal_mitochondrial_physio0.97199363
108MP0005023_abnormal_wound_healing0.96541420
109MP0002736_abnormal_nociception_after0.95101771
110MP0002269_muscular_atrophy0.94815851
111MP0005266_abnormal_metabolism0.94655240
112MP0003938_abnormal_ear_development0.92934247
113MP0005395_other_phenotype0.92568609
114MP0005646_abnormal_pituitary_gland0.91483982
115MP0002751_abnormal_autonomic_nervous0.90629580
116MP0005647_abnormal_sex_gland0.88855248
117MP0003866_abnormal_defecation0.88570577
118MP0000579_abnormal_nail_morphology0.88152247
119MP0000762_abnormal_tongue_morphology0.87843836
120MP0002132_abnormal_respiratory_system0.87732920
121MP0001145_abnormal_male_reproductive0.87107372
122MP0005410_abnormal_fertilization0.85764237
123MP0008789_abnormal_olfactory_epithelium0.85302502
124MP0009643_abnormal_urine_homeostasis0.84295901
125MP0008007_abnormal_cellular_replicative0.82869767
126MP0003787_abnormal_imprinting0.82720456
127MP0005551_abnormal_eye_electrophysiolog0.81612114
128MP0000467_abnormal_esophagus_morphology0.81323104
129MP0003172_abnormal_lysosome_physiology0.80376795
130MP0002837_dystrophic_cardiac_calcinosis0.80048002
131MP0000230_abnormal_systemic_arterial0.79900638
132MP0000613_abnormal_salivary_gland0.79820505
133MP0000432_abnormal_head_morphology0.79521130
134MP0003936_abnormal_reproductive_system0.77822457
135MP0002932_abnormal_joint_morphology0.77571391
136MP0005671_abnormal_response_to0.76995327
137MP0003935_abnormal_craniofacial_develop0.74780550
138MP0009765_abnormal_xenobiotic_induced0.73436236
139MP0002114_abnormal_axial_skeleton0.73334390
140MP0000631_abnormal_neuroendocrine_gland0.73046973
141MP0004215_abnormal_myocardial_fiber0.72644110
142MP0003186_abnormal_redox_activity0.71165341
143MP0005220_abnormal_exocrine_pancreas0.70985170
144MP0001119_abnormal_female_reproductive0.70603635
145MP0009672_abnormal_birth_weight0.69750571
146MP0005075_abnormal_melanosome_morpholog0.69225050
147MP0010155_abnormal_intestine_physiology0.67893777
148MP0005058_abnormal_lysosome_morphology0.67844007
149MP0004185_abnormal_adipocyte_glucose0.67679420
150MP0003755_abnormal_palate_morphology0.67678897
151MP0002075_abnormal_coat/hair_pigmentati0.67070621
152MP0003123_paternal_imprinting0.66266891
153MP0001873_stomach_inflammation0.64923437
154MP0002925_abnormal_cardiovascular_devel0.63773011
155MP0002210_abnormal_sex_determination0.62733638
156MP0000653_abnormal_sex_gland0.61726962
157MP0001340_abnormal_eyelid_morphology0.61374755
158MP0002697_abnormal_eye_size0.59949540
159MP0003828_pulmonary_edema0.59636761
160MP0003136_yellow_coat_color0.59341700
161MP0003861_abnormal_nervous_system0.58036188
162MP0009333_abnormal_splenocyte_physiolog0.55282311
163MP0008770_decreased_survivor_rate0.55062267

Predicted human phenotypes

RankGene SetZ-score
1Rib fusion (HP:0000902)5.17381740
2Rectal fistula (HP:0100590)4.40519434
3Rectovaginal fistula (HP:0000143)4.40519434
4Short humerus (HP:0005792)4.33782390
5Aplasia/hypoplasia of the humerus (HP:0006507)4.28493506
6Facial hemangioma (HP:0000329)4.22981368
7Chronic bronchitis (HP:0004469)4.17178729
8Absent radius (HP:0003974)3.95848116
9Intestinal fistula (HP:0100819)3.94880082
10Annular pancreas (HP:0001734)3.92590073
11Pustule (HP:0200039)3.90873534
12Vaginal fistula (HP:0004320)3.88435522
13Concave nail (HP:0001598)3.84391262
14Absent forearm bone (HP:0003953)3.71270993
15Aplasia involving forearm bones (HP:0009822)3.71270993
16Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.70965981
17Hyperactive renin-angiotensin system (HP:0000841)3.59374942
18Ulnar bowing (HP:0003031)3.56050197
19Vertebral hypoplasia (HP:0008417)3.51729697
20Aplasia/Hypoplasia of the vertebrae (HP:0008515)3.51729697
21Decreased circulating renin level (HP:0003351)3.51705976
22Tongue fasciculations (HP:0001308)3.47934923
23Poikiloderma (HP:0001029)3.47838216
24Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.45383446
25Selective tooth agenesis (HP:0001592)3.35151789
26Ependymoma (HP:0002888)3.31486572
27Alopecia of scalp (HP:0002293)3.24675934
28Muscle fibrillation (HP:0010546)3.24087980
29Abnormality of the labia minora (HP:0012880)3.20542460
30Hypochromic microcytic anemia (HP:0004840)3.18114318
31Patellar aplasia (HP:0006443)3.10377832
32Absent thumb (HP:0009777)3.08962759
33Intestinal atresia (HP:0011100)3.08044830
34Abnormal hemoglobin (HP:0011902)3.04555724
35Abnormality of the astrocytes (HP:0100707)3.04305785
36Astrocytoma (HP:0009592)3.04305785
37Abolished electroretinogram (ERG) (HP:0000550)3.02771849
38Orthostatic hypotension (HP:0001278)3.01261239
39Basal cell carcinoma (HP:0002671)3.01121108
40Rhinitis (HP:0012384)2.99443591
41Absent/shortened dynein arms (HP:0200106)2.99283821
42Dynein arm defect of respiratory motile cilia (HP:0012255)2.99283821
43Increased IgM level (HP:0003496)2.94567321
44Turricephaly (HP:0000262)2.93315051
45Male infertility (HP:0003251)2.90628220
46Abnormality of serine family amino acid metabolism (HP:0010894)2.89282140
47Abnormality of glycine metabolism (HP:0010895)2.89282140
48Abnormal respiratory motile cilium morphology (HP:0005938)2.88540082
49Abnormal respiratory epithelium morphology (HP:0012253)2.88540082
50Methylmalonic aciduria (HP:0012120)2.87814614
51Abnormality of renin-angiotensin system (HP:0000847)2.87266805
52Abnormal respiratory motile cilium physiology (HP:0012261)2.85766355
53Abnormality of the vitamin B12 metabolism (HP:0004341)2.82885881
54Aplasia/Hypoplasia of the patella (HP:0006498)2.82669148
55Abdominal situs inversus (HP:0003363)2.81876540
56Abnormality of abdominal situs (HP:0011620)2.81876540
57Neoplasm of the oral cavity (HP:0100649)2.79043322
58Carpal bone hypoplasia (HP:0001498)2.78031719
59Hyperglycinemia (HP:0002154)2.75326102
60Methylmalonic acidemia (HP:0002912)2.74489656
61Stenosis of the external auditory canal (HP:0000402)2.69131587
62Abnormality of vitamin B metabolism (HP:0004340)2.69104166
63Squamous cell carcinoma (HP:0002860)2.67520183
64Breast hypoplasia (HP:0003187)2.67344469
65Hyperglycinuria (HP:0003108)2.65866241
66Abnormal ciliary motility (HP:0012262)2.59799718
67Abnormality of aspartate family amino acid metabolism (HP:0010899)2.56832873
68Gastrointestinal atresia (HP:0002589)2.56524044
69Short hallux (HP:0010109)2.56378758
70Congenital hip dislocation (HP:0001374)2.54371455
71Aplasia/Hypoplasia of the hallux (HP:0008362)2.54287654
72Abnormality of serum amino acid levels (HP:0003112)2.53392845
73Shawl scrotum (HP:0000049)2.51815143
74Vertebral fusion (HP:0002948)2.51358762
75Fused cervical vertebrae (HP:0002949)2.49426843
76Abnormality of glutamine family amino acid metabolism (HP:0010902)2.48556520
77Bronchiectasis (HP:0002110)2.47570635
78Abnormality of the middle phalanges of the toes (HP:0010183)2.47498672
79Broad alveolar ridges (HP:0000187)2.47454916
80Pendular nystagmus (HP:0012043)2.43150269
81True hermaphroditism (HP:0010459)2.42942130
82Coronal craniosynostosis (HP:0004440)2.38460165
83Pancreatic cysts (HP:0001737)2.34676638
84Esophageal atresia (HP:0002032)2.34334691
85Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.32130477
86Short 1st metacarpal (HP:0010034)2.32130477
87Glioma (HP:0009733)2.28572164
88Short chin (HP:0000331)2.27702837
89Abnormality of the 1st metacarpal (HP:0010009)2.27228196
90Vertebral clefting (HP:0008428)2.26462612
91Abnormal number of incisors (HP:0011064)2.25504338
92Volvulus (HP:0002580)2.19582942
93Spinal muscular atrophy (HP:0007269)2.19529291
94Premature graying of hair (HP:0002216)2.18441560
95Rhabdomyosarcoma (HP:0002859)2.18228892
96Hypoplasia of the radius (HP:0002984)2.17795121
97Dysautonomia (HP:0002459)2.16307393
98Asplenia (HP:0001746)2.15851811
99Bilateral microphthalmos (HP:0007633)2.15674148
100Alacrima (HP:0000522)2.15274041
101Abnormality of male internal genitalia (HP:0000022)2.14248185
102Short phalanx of the thumb (HP:0009660)2.13710936
103Aplasia/Hypoplasia of the spleen (HP:0010451)2.12338351
104Supernumerary spleens (HP:0009799)2.12274701
105Abnormality of vitamin metabolism (HP:0100508)2.12101865
106Hypoplasia of the uterus (HP:0000013)2.10452840
107Short thumb (HP:0009778)2.09550833
108Pancreatic fibrosis (HP:0100732)2.07569118
109Anteriorly placed anus (HP:0001545)2.06723801
110Missing ribs (HP:0000921)2.05869272
111Bowing of the arm (HP:0006488)2.05155937
112Bowed forearm bones (HP:0003956)2.05155937
113Metabolic alkalosis (HP:0200114)2.04308402
114Abnormality of the aortic arch (HP:0012303)2.04200354
115Hypotrichosis (HP:0001006)2.03075757
116Hyperaldosteronism (HP:0000859)2.02777559
117Hypotelorism (HP:0000601)2.02666204
118Medulloblastoma (HP:0002885)2.01887744
119Hamartoma (HP:0010566)2.01268151
120Chromosomal breakage induced by crosslinking agents (HP:0003221)2.00214416
121Abnormality of the lower motor neuron (HP:0002366)1.98703206
122Short 5th finger (HP:0009237)1.97621197
123Albinism (HP:0001022)1.94201353
124Premature skin wrinkling (HP:0100678)1.93197849
125Choanal stenosis (HP:0000452)1.92837716
126Agnosia (HP:0010524)1.89149317
127Meckel diverticulum (HP:0002245)1.89073350
128Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.88675148
129Aplasia/hypoplasia of the uterus (HP:0008684)1.88568012
130Colon cancer (HP:0003003)1.88083902
131Multiple enchondromatosis (HP:0005701)1.87990050
132Decreased electroretinogram (ERG) amplitude (HP:0000654)1.86854215
133Neoplasm of striated muscle (HP:0009728)1.86726102
134Hypochromic anemia (HP:0001931)1.86498199
135Abnormality of the ileum (HP:0001549)1.85893390
136Hypoglycemic seizures (HP:0002173)1.85549087
137Congenital sensorineural hearing impairment (HP:0008527)1.84059501
138Hemivertebrae (HP:0002937)1.83901311
139Alkalosis (HP:0001948)1.83597212
140Horseshoe kidney (HP:0000085)1.83138673
141Mucopolysacchariduria (HP:0008155)1.82744221
142Urinary glycosaminoglycan excretion (HP:0003541)1.82744221
143Diaphragmatic weakness (HP:0009113)1.82163889
144Split hand (HP:0001171)1.82104591
145Prostate neoplasm (HP:0100787)1.81935087
146Abnormal lung lobation (HP:0002101)1.81476421
147Aplasia of the musculature (HP:0100854)1.81426106
148Hypoplasia of the ulna (HP:0003022)1.81396219
149Bronchitis (HP:0012387)1.80370612
150Cerebral aneurysm (HP:0004944)1.79809969
151Acute encephalopathy (HP:0006846)1.79041578
152Gastrointestinal dysmotility (HP:0002579)1.78615195
153Biliary tract neoplasm (HP:0100574)1.78366226
154Chromsome breakage (HP:0040012)1.77726728
155Pancreatic islet-cell hyperplasia (HP:0004510)1.77442677
156Male pseudohermaphroditism (HP:0000037)1.77005838
157IgA deficiency (HP:0002720)1.76214525
158Abnormality of chromosome stability (HP:0003220)1.76100635
159Renal salt wasting (HP:0000127)1.75942562
160Intrahepatic cholestasis (HP:0001406)1.75811717
161Metaphyseal cupping (HP:0003021)1.75490435
162Bifid uvula (HP:0000193)1.75376224
163Premature ovarian failure (HP:0008209)1.75105103
164Posterior subcapsular cataract (HP:0007787)1.74642488
165Abnormality of chloride homeostasis (HP:0011422)1.74258398
166Symptomatic seizures (HP:0011145)1.72558544
167Gonadotropin excess (HP:0000837)1.71679986
168Hydroxyprolinuria (HP:0003080)1.71438302
169Abnormality of proline metabolism (HP:0010907)1.71438302
170Megaloblastic anemia (HP:0001889)1.71296949
171Nephronophthisis (HP:0000090)1.71064605
172Acute necrotizing encephalopathy (HP:0006965)1.70685063
173Birth length less than 3rd percentile (HP:0003561)1.70357073
174Aplasia/Hypoplasia of the uvula (HP:0010293)1.69258468
175Aplasia/Hypoplasia involving the musculature (HP:0001460)1.69245915
176Stomach cancer (HP:0012126)1.68473015
177Abnormality of the preputium (HP:0100587)1.67774198
178Hypomagnesemia (HP:0002917)1.67544973
179Abnormality of magnesium homeostasis (HP:0004921)1.67185628
180Lethargy (HP:0001254)1.67032213
181Abnormality of sulfur amino acid metabolism (HP:0004339)1.66700632
182Molar tooth sign on MRI (HP:0002419)1.65389584
183Abnormality of midbrain morphology (HP:0002418)1.65389584
184Confusion (HP:0001289)1.64205349
185Abnormality of the proximal phalanges of the hand (HP:0009834)1.62924031

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK5.34227540
2DDR24.18637813
3MAP3K63.55427993
4MAPK153.49917665
5MAP3K113.01780504
6ZAK2.90852042
7MATK2.80913151
8NUAK12.63080170
9CDK122.62082926
10TYRO32.60550682
11TNIK2.58797873
12VRK22.52897398
13GRK12.51521987
14FGR2.45751172
15EPHA22.40801899
16OXSR12.38491096
17MKNK22.37592537
18CDK72.30351723
19FRK2.26556362
20AKT32.22357720
21BMX2.19102381
22TSSK62.18985894
23TRIM282.17358852
24WNK32.10500902
25DAPK12.01418306
26EIF2AK31.97681982
27PINK11.96206678
28PLK41.96012321
29STK161.95343112
30TLK11.94270836
31TAF11.88657848
32PLK31.82609012
33PIM21.82524637
34CSK1.78192888
35MKNK11.76837939
36BMPR1B1.74824088
37RPS6KB21.72297591
38STK391.71095221
39PBK1.71012472
40SRPK11.70002759
41PDGFRA1.67334714
42YES11.66915009
43CDK191.59909888
44UHMK11.58333736
45PRKD21.57652243
46LATS21.57595110
47WEE11.54185006
48PIM11.53203092
49CDK61.52862558
50DYRK1B1.49977811
51CDC71.43823187
52BUB11.42746825
53VRK11.38324857
54PDK21.36231128
55PLK11.34051309
56ADRBK21.33676387
57CHEK21.33348214
58MAP3K101.32848713
59BRSK21.32500986
60TTK1.24828624
61NEK11.24384732
62NEK21.21282889
63NME11.18791550
64NLK1.16775021
65STK241.15653945
66TXK1.11153498
67DYRK31.09311064
68RPS6KL11.08907838
69RPS6KC11.08907838
70STK101.08199656
71MAP4K21.01197576
72MTOR0.96908441
73TRPM70.95385194
74CDC42BPA0.94499106
75MST40.94276819
76CSNK1G10.94103190
77PAK40.93597321
78MAPKAPK30.92619182
79RPS6KA60.90983369
80MAPK110.90127576
81TESK20.89224529
82GSK3A0.89141230
83ATR0.88545142
84EIF2AK20.85414897
85INSRR0.83873416
86AURKB0.80730074
87ALK0.79960310
88MAP3K90.78732163
89PRKCI0.78169734
90MAP3K80.77696224
91PASK0.75072089
92TIE10.72579063
93AURKA0.71508909
94CDK20.71102680
95CHEK10.70328541
96RPS6KA10.69766175
97CSNK1G20.68025217
98EEF2K0.66453162
99PLK20.64975652
100CSNK1G30.63529560
101CDK40.63264564
102LATS10.63020106
103LMTK20.62730754
104MAP2K20.61851036
105MET0.61188654
106BCKDK0.60764764
107SCYL20.60605312
108TAOK30.56771379
109RIPK10.55762410
110BRD40.54720254
111TEC0.54421155
112SMG10.53074702
113FLT30.52585827
114TAOK20.51371859
115ATM0.50824119
116KDR0.50805244
117FER0.50243528
118GRK60.50007529
119PRKAA10.49768380
120PAK10.49637546
121GRK50.49273776
122IKBKB0.48371495
123RAF10.47716195
124CSNK1A10.46085501
125CSNK2A10.45941595
126STK30.45765839
127PRKCQ0.45416676
128PTK20.44936598
129CSNK2A20.43415897
130IGF1R0.43104127
131PIK3CA0.42916555
132TAOK10.41032365
133CDK90.40921807
134MAPK10.40907522
135ERBB30.40407202
136STK38L0.39298297
137EGFR0.37957995
138AKT20.37826105
139PRKCE0.37672259
140TGFBR10.37386299
141WNK40.37172265
142MST1R0.36396042
143CDK10.36288985
144PHKG20.36238609
145PHKG10.36238609
146PAK20.35470831
147ERBB40.34596842
148PRKCA0.34380150
149FGFR20.34019520
150HIPK20.33846290
151MUSK0.33603925
152MAPK140.33367516
153RPS6KB10.32308181
154CSNK1E0.30807744
155DYRK20.30203007
156CSNK1A1L0.29539077
157ACVR1B0.29181106
158PRKG20.29017271
159MAPK30.27361113
160GRK70.26379290
161MAPKAPK20.24613722
162MELK0.23017165
163FGFR10.22066965
164MAPK100.21997543
165STK40.21119064

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034305.20771023
2DNA replication_Homo sapiens_hsa030304.36019598
3Base excision repair_Homo sapiens_hsa034104.15247461
4Fatty acid biosynthesis_Homo sapiens_hsa000613.16088504
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.14993768
6RNA transport_Homo sapiens_hsa030132.73854311
7Spliceosome_Homo sapiens_hsa030402.70444288
8Nucleotide excision repair_Homo sapiens_hsa034202.59922543
9Vitamin digestion and absorption_Homo sapiens_hsa049772.33065746
10Sulfur metabolism_Homo sapiens_hsa009202.22793017
11Homologous recombination_Homo sapiens_hsa034402.22558510
12mRNA surveillance pathway_Homo sapiens_hsa030152.11485073
13Caffeine metabolism_Homo sapiens_hsa002322.10432976
14Nitrogen metabolism_Homo sapiens_hsa009102.01719857
15Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.00582140
16Cell cycle_Homo sapiens_hsa041101.93319091
17Hippo signaling pathway_Homo sapiens_hsa043901.90193724
18Fanconi anemia pathway_Homo sapiens_hsa034601.88926056
19Linoleic acid metabolism_Homo sapiens_hsa005911.84729468
20Ribosome_Homo sapiens_hsa030101.84506121
21Retinol metabolism_Homo sapiens_hsa008301.82923222
22p53 signaling pathway_Homo sapiens_hsa041151.80806067
23Chemical carcinogenesis_Homo sapiens_hsa052041.71821942
24Adherens junction_Homo sapiens_hsa045201.71649593
25Tryptophan metabolism_Homo sapiens_hsa003801.71543803
26One carbon pool by folate_Homo sapiens_hsa006701.70819004
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.69939941
28Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.69397854
29* Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.65212776
30Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.64173976
31Notch signaling pathway_Homo sapiens_hsa043301.62276692
32alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.61940814
33mTOR signaling pathway_Homo sapiens_hsa041501.61054438
34Hedgehog signaling pathway_Homo sapiens_hsa043401.54312775
35Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.52217399
36Histidine metabolism_Homo sapiens_hsa003401.51942107
37Biosynthesis of amino acids_Homo sapiens_hsa012301.49074820
382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.44288363
39Propanoate metabolism_Homo sapiens_hsa006401.42034851
40Fructose and mannose metabolism_Homo sapiens_hsa000511.39547171
41Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.38780821
42Bladder cancer_Homo sapiens_hsa052191.38686276
43TGF-beta signaling pathway_Homo sapiens_hsa043501.37616294
44Arginine and proline metabolism_Homo sapiens_hsa003301.34855487
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34524810
46Folate biosynthesis_Homo sapiens_hsa007901.34338848
47RNA polymerase_Homo sapiens_hsa030201.29122604
48Basal cell carcinoma_Homo sapiens_hsa052171.28126421
49Ether lipid metabolism_Homo sapiens_hsa005651.27708404
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.26791534
51Intestinal immune network for IgA production_Homo sapiens_hsa046721.25130404
52Vitamin B6 metabolism_Homo sapiens_hsa007501.24199904
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.24190704
54Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.22994850
55Sulfur relay system_Homo sapiens_hsa041221.22909750
56Arachidonic acid metabolism_Homo sapiens_hsa005901.17852185
57Starch and sucrose metabolism_Homo sapiens_hsa005001.16707580
58Transcriptional misregulation in cancer_Homo sapiens_hsa052021.16307419
59Pyruvate metabolism_Homo sapiens_hsa006201.15715164
60Fatty acid elongation_Homo sapiens_hsa000621.15236415
61Asthma_Homo sapiens_hsa053101.12691126
62Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.10428078
63Steroid hormone biosynthesis_Homo sapiens_hsa001401.10413873
64Tight junction_Homo sapiens_hsa045301.09707943
65Fatty acid degradation_Homo sapiens_hsa000711.06940525
66Drug metabolism - other enzymes_Homo sapiens_hsa009831.06776956
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.04102055
68Thyroid cancer_Homo sapiens_hsa052161.03745226
69Protein export_Homo sapiens_hsa030601.02414939
70Oocyte meiosis_Homo sapiens_hsa041140.98936837
71Shigellosis_Homo sapiens_hsa051310.98823256
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.98355366
73Phototransduction_Homo sapiens_hsa047440.97988203
74Steroid biosynthesis_Homo sapiens_hsa001000.97772878
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.95685096
76Pyrimidine metabolism_Homo sapiens_hsa002400.93925723
77MicroRNAs in cancer_Homo sapiens_hsa052060.92847792
78Primary bile acid biosynthesis_Homo sapiens_hsa001200.92731902
79Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92706019
80RNA degradation_Homo sapiens_hsa030180.92442990
81Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.92374988
82Circadian rhythm_Homo sapiens_hsa047100.91099414
83Wnt signaling pathway_Homo sapiens_hsa043100.89048928
84Peroxisome_Homo sapiens_hsa041460.85980951
85Glycerolipid metabolism_Homo sapiens_hsa005610.85580580
86Lysine degradation_Homo sapiens_hsa003100.85557137
87beta-Alanine metabolism_Homo sapiens_hsa004100.85072098
88Colorectal cancer_Homo sapiens_hsa052100.84665879
89Longevity regulating pathway - mammal_Homo sapiens_hsa042110.84443653
90Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.83742998
91Viral carcinogenesis_Homo sapiens_hsa052030.83075442
92Protein digestion and absorption_Homo sapiens_hsa049740.82417069
93Galactose metabolism_Homo sapiens_hsa000520.82349694
94Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81754902
95Purine metabolism_Homo sapiens_hsa002300.79418279
96Basal transcription factors_Homo sapiens_hsa030220.78708372
97Proteasome_Homo sapiens_hsa030500.78543044
98Mineral absorption_Homo sapiens_hsa049780.76871935
99Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74996451
100Type I diabetes mellitus_Homo sapiens_hsa049400.74215915
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.72647095
102Graft-versus-host disease_Homo sapiens_hsa053320.72314707
103Metabolic pathways_Homo sapiens_hsa011000.71967612
104Allograft rejection_Homo sapiens_hsa053300.70125571
105Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69873996
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.69382378
107Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.69298664
108Small cell lung cancer_Homo sapiens_hsa052220.69238086
109VEGF signaling pathway_Homo sapiens_hsa043700.69056226
110Autoimmune thyroid disease_Homo sapiens_hsa053200.67100598
111Glutathione metabolism_Homo sapiens_hsa004800.66932018
112Acute myeloid leukemia_Homo sapiens_hsa052210.64529599
113Legionellosis_Homo sapiens_hsa051340.61728655
114Oxidative phosphorylation_Homo sapiens_hsa001900.61587557
115Huntingtons disease_Homo sapiens_hsa050160.61247982
116Central carbon metabolism in cancer_Homo sapiens_hsa052300.58408808
117Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.57986728
118Epstein-Barr virus infection_Homo sapiens_hsa051690.57899054
119Cyanoamino acid metabolism_Homo sapiens_hsa004600.56300368
120Butanoate metabolism_Homo sapiens_hsa006500.55833554
121Herpes simplex infection_Homo sapiens_hsa051680.52953096
122Non-homologous end-joining_Homo sapiens_hsa034500.52741078
123Chronic myeloid leukemia_Homo sapiens_hsa052200.52518463
124Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51027258
125Tyrosine metabolism_Homo sapiens_hsa003500.50671418
126Parkinsons disease_Homo sapiens_hsa050120.49969318
127Phenylalanine metabolism_Homo sapiens_hsa003600.49460633
128Selenocompound metabolism_Homo sapiens_hsa004500.47633159
129Pancreatic secretion_Homo sapiens_hsa049720.46417934
130Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.46330387
131Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45881100
132Cysteine and methionine metabolism_Homo sapiens_hsa002700.45060637
133Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44267542
134HTLV-I infection_Homo sapiens_hsa051660.43085691
135AMPK signaling pathway_Homo sapiens_hsa041520.42396749
136Pathways in cancer_Homo sapiens_hsa052000.42110718
137Endometrial cancer_Homo sapiens_hsa052130.42061639
138Viral myocarditis_Homo sapiens_hsa054160.41402766
139Proteoglycans in cancer_Homo sapiens_hsa052050.40479903
140Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37597764
141Dorso-ventral axis formation_Homo sapiens_hsa043200.37020834
142HIF-1 signaling pathway_Homo sapiens_hsa040660.36223718
143Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35066298
144Choline metabolism in cancer_Homo sapiens_hsa052310.34299707
145ErbB signaling pathway_Homo sapiens_hsa040120.32972995
146Renin-angiotensin system_Homo sapiens_hsa046140.32951752
147Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.32825483
148Maturity onset diabetes of the young_Homo sapiens_hsa049500.31128839
149Arginine biosynthesis_Homo sapiens_hsa002200.29346892
150Apoptosis_Homo sapiens_hsa042100.28622907
151Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26784918
152Prostate cancer_Homo sapiens_hsa052150.26505061
153Glycosaminoglycan degradation_Homo sapiens_hsa005310.26018194
154Fatty acid metabolism_Homo sapiens_hsa012120.25546981
155Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.24093665
156Primary immunodeficiency_Homo sapiens_hsa053400.23910844
157Gap junction_Homo sapiens_hsa045400.23723961
158Fat digestion and absorption_Homo sapiens_hsa049750.23132625
159PI3K-Akt signaling pathway_Homo sapiens_hsa041510.21037930
160Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.20976139
161Insulin signaling pathway_Homo sapiens_hsa049100.19374772
162N-Glycan biosynthesis_Homo sapiens_hsa005100.18781848

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