ATXN7L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.19184763
2positive regulation of gamma-delta T cell activation (GO:0046645)5.17870334
3tolerance induction (GO:0002507)4.61201727
4antigen processing and presentation of endogenous antigen (GO:0019883)4.32158641
5neutrophil activation involved in immune response (GO:0002283)4.27199227
6antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.08250267
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.08250267
8myeloid dendritic cell activation (GO:0001773)4.04183842
9regulation of interleukin-12 biosynthetic process (GO:0045075)3.91966452
10myeloid dendritic cell differentiation (GO:0043011)3.91633702
11neutrophil activation (GO:0042119)3.84354150
12negative regulation of T cell mediated immunity (GO:0002710)3.74978870
13positive regulation of B cell differentiation (GO:0045579)3.74750132
14positive regulation of interferon-alpha production (GO:0032727)3.72848485
15positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.71850823
16regulation of B cell receptor signaling pathway (GO:0050855)3.67446191
17negative regulation of interleukin-12 production (GO:0032695)3.67059216
18response to type I interferon (GO:0034340)3.65329539
19granulocyte activation (GO:0036230)3.65278223
20regulation of T-helper 1 cell differentiation (GO:0045625)3.64092639
21type I interferon signaling pathway (GO:0060337)3.63596422
22cellular response to type I interferon (GO:0071357)3.63596422
23positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.62016353
24positive regulation of antigen processing and presentation (GO:0002579)3.58080863
25regulation of interferon-alpha production (GO:0032647)3.56132906
26defense response to protozoan (GO:0042832)3.55755127
27histone H3-K36 demethylation (GO:0070544)3.52490071
28regulation of chronic inflammatory response (GO:0002676)3.50915454
29neutrophil mediated immunity (GO:0002446)3.49720917
30response to muramyl dipeptide (GO:0032495)3.48185138
31regulation of gamma-delta T cell activation (GO:0046643)3.47914089
32mast cell activation (GO:0045576)3.47673483
33interferon-gamma secretion (GO:0072643)3.46110848
34T-helper 1 type immune response (GO:0042088)3.45048747
35positive regulation of interleukin-2 production (GO:0032743)3.44916072
36regulation of interferon-beta biosynthetic process (GO:0045357)3.44227438
37regulation of B cell differentiation (GO:0045577)3.43981380
38positive regulation of interferon-beta production (GO:0032728)3.42512730
39positive regulation of natural killer cell differentiation (GO:0032825)3.40708979
40NIK/NF-kappaB signaling (GO:0038061)3.39617082
41regulation of activation of Janus kinase activity (GO:0010533)3.38758681
42dendritic cell chemotaxis (GO:0002407)3.38544006
43cellular response to exogenous dsRNA (GO:0071360)3.38133141
44regulation of gamma-delta T cell differentiation (GO:0045586)3.37794028
45negative regulation of cell killing (GO:0031342)3.37479130
46negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.37479130
47respiratory burst (GO:0045730)3.36632623
48positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.36162060
49positive regulation by symbiont of host defense response (GO:0052509)3.34378755
50modulation by symbiont of host defense response (GO:0052031)3.34378755
51modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.34378755
52modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.34378755
53positive regulation by organism of defense response of other organism involved in symbiotic interact3.34378755
54modulation by symbiont of host immune response (GO:0052553)3.34378755
55T cell migration (GO:0072678)3.34290779
56cellular extravasation (GO:0045123)3.34018104
57interferon-gamma production (GO:0032609)3.32927439
58negative T cell selection (GO:0043383)3.32415514
59negative regulation of translation, ncRNA-mediated (GO:0040033)3.31022399
60regulation of translation, ncRNA-mediated (GO:0045974)3.31022399
61negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.31022399
62interferon-gamma-mediated signaling pathway (GO:0060333)3.30748954
63negative thymic T cell selection (GO:0045060)3.29935211
64activated T cell proliferation (GO:0050798)3.29461774
65response to protozoan (GO:0001562)3.29345142
66positive regulation of interleukin-12 production (GO:0032735)3.28217327
67regulation of alpha-beta T cell proliferation (GO:0046640)3.27670644
68immunoglobulin mediated immune response (GO:0016064)3.24417800
69response to peptidoglycan (GO:0032494)3.22556032
70regulation of MHC class II biosynthetic process (GO:0045346)3.19258387
71positive regulation of tolerance induction (GO:0002645)3.17911641
72B cell receptor signaling pathway (GO:0050853)3.17563181
73positive regulation of isotype switching (GO:0045830)3.17291281
74cellular response to interferon-beta (GO:0035458)3.17242314
75positive regulation of granulocyte differentiation (GO:0030854)3.16904014
76positive regulation of defense response to virus by host (GO:0002230)3.16070746
77positive regulation of alpha-beta T cell proliferation (GO:0046641)3.15124793
78myeloid leukocyte mediated immunity (GO:0002444)3.15096529
79myeloid cell activation involved in immune response (GO:0002275)3.14529663
80regulation of dendritic cell antigen processing and presentation (GO:0002604)3.14477336
81leukocyte aggregation (GO:0070486)3.13473782
82lipopolysaccharide-mediated signaling pathway (GO:0031663)3.12212485
83positive T cell selection (GO:0043368)3.09527723
84mature B cell differentiation (GO:0002335)3.07947883
85regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)3.06079412
86negative regulation of interleukin-17 production (GO:0032700)3.05878592
87T cell selection (GO:0045058)3.04835669
88regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.03387512
89positive regulation of DNA recombination (GO:0045911)3.02120522
90negative regulation of lymphocyte mediated immunity (GO:0002707)3.01250187
91germinal center formation (GO:0002467)3.01009134
92positive regulation of humoral immune response (GO:0002922)2.99801962
93dendritic cell differentiation (GO:0097028)2.98503911
94positive regulation of mRNA catabolic process (GO:0061014)2.96127681
95regulation of T cell tolerance induction (GO:0002664)2.95937065
96regulation of tolerance induction (GO:0002643)2.95922659
97detection of other organism (GO:0098543)2.95818829
98regulation of antigen processing and presentation (GO:0002577)2.95457256
99myeloid leukocyte activation (GO:0002274)2.95432019
100regulation of RIG-I signaling pathway (GO:0039535)2.94888381
101response to interleukin-15 (GO:0070672)2.94330937
102positive regulation of immunoglobulin mediated immune response (GO:0002891)2.93733375
103positive regulation of B cell mediated immunity (GO:0002714)2.93733375
104regulation of hypersensitivity (GO:0002883)2.92898672
105dendritic cell migration (GO:0036336)2.89860384
106cellular response to interleukin-15 (GO:0071350)2.88977835
107regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.88229818
108positive regulation of T-helper cell differentiation (GO:0045624)2.86432396
109positive regulation of interferon-gamma production (GO:0032729)2.86146804
110negative regulation of viral genome replication (GO:0045071)2.86031781
111natural killer cell activation (GO:0030101)2.85961274
112macrophage activation involved in immune response (GO:0002281)2.85576998
113regulation of interferon-beta production (GO:0032648)2.85315708
114B cell mediated immunity (GO:0019724)2.84986206
115regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.84029079
116positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.84029079
117T cell homeostasis (GO:0043029)2.83836373
118cellular response to zinc ion (GO:0071294)2.83634622
119response to interferon-beta (GO:0035456)2.83447589
120positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.83354574
121production of molecular mediator involved in inflammatory response (GO:0002532)2.82737425
122positive regulation of cellular amide metabolic process (GO:0034250)2.81793918
123positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.81747275
124regulation of germinal center formation (GO:0002634)2.81441302
125regulation of interleukin-12 production (GO:0032655)2.80542898
126regulation of T-helper cell differentiation (GO:0045622)2.80491848
127regulation of interleukin-2 biosynthetic process (GO:0045076)2.80365278
128positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.79587275
129leukocyte degranulation (GO:0043299)2.78880458
130detection of bacterium (GO:0016045)2.78441333
131negative regulation of interleukin-1 beta production (GO:0032691)2.77635587
132microglial cell activation (GO:0001774)2.76769176
133regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.76691101
134regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.76676622
135B cell homeostasis (GO:0001782)2.76159895
136positive regulation of B cell activation (GO:0050871)2.75939955
137positive regulation of interleukin-10 production (GO:0032733)2.75815741
138regulation of regulatory T cell differentiation (GO:0045589)2.75448333
139negative regulation of T-helper cell differentiation (GO:0045623)2.70907394
140negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.70907394
141Arp2/3 complex-mediated actin nucleation (GO:0034314)2.66449385
142regulation of isotype switching (GO:0045191)2.66201006
143cellular response to ethanol (GO:0071361)2.66090142
144negative regulation of type 2 immune response (GO:0002829)2.64407991
145regulation of mRNA catabolic process (GO:0061013)2.58147292
146regulation of chemokine biosynthetic process (GO:0045073)2.55703277

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.14595299
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.52489889
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.25615227
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.90603838
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.81938729
6* IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.62824009
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.13180969
8* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.84444390
9* IRF8_27001747_Chip-Seq_BMDM_Mouse3.63452165
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.44792417
11SCL_19346495_ChIP-Seq_HPC-7_Human3.42109221
12STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.37452109
13NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.98107799
14* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.90701780
15KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.78418468
16KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.78418468
17KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.78418468
18STAT4_19710469_ChIP-ChIP_TH1__Mouse2.77465481
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.72302600
20RUNX_20019798_ChIP-Seq_JUKART_Human2.67948784
21Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.42337956
22FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.31324880
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.28661163
24* MYB_26560356_Chip-Seq_TH2_Human2.23811575
25* SPI1_23547873_ChIP-Seq_NB4_Human2.20444961
26VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.19401171
27LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.94608442
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.91999108
29MYB_26560356_Chip-Seq_TH1_Human1.90495665
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.88880653
31MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.78267813
32* SPI1_23127762_ChIP-Seq_K562_Human1.76879682
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.74213043
34LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.73272854
35RUNX1_22412390_ChIP-Seq_EML_Mouse1.73061724
36* MAF_26560356_Chip-Seq_TH1_Human1.72486049
37FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.71501325
38ZNF274_21170338_ChIP-Seq_K562_Hela1.70429384
39VDR_24763502_ChIP-Seq_THP-1_Human1.69500066
40VDR_24787735_ChIP-Seq_THP-1_Human1.68380991
41BRD4_27068464_Chip-Seq_AML-cells_Mouse1.68310556
42ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.63686114
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.63321207
44SALL1_21062744_ChIP-ChIP_HESCs_Human1.62742769
45PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.59497249
46* GATA1_19941827_ChIP-Seq_MEL_Mouse1.58972269
47VDR_21846776_ChIP-Seq_THP-1_Human1.57566683
48PU_27001747_Chip-Seq_BMDM_Mouse1.56816489
49GATA1_22025678_ChIP-Seq_K562_Human1.56078136
50PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.53611173
51CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.51520054
52TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41601125
53CIITA_25753668_ChIP-Seq_RAJI_Human1.39615855
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.36330127
55GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.34999028
56CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.34383420
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.33212896
58CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30715528
59* GATA3_27048872_Chip-Seq_THYMUS_Human1.29318446
60* GATA3_26560356_Chip-Seq_TH2_Human1.27469489
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.26966944
62GATA2_21666600_ChIP-Seq_HMVEC_Human1.24648643
63IKZF1_21737484_ChIP-ChIP_HCT116_Human1.23529500
64TCF7_22412390_ChIP-Seq_EML_Mouse1.22593994
65KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.21938845
66GATA2_22383799_ChIP-Seq_G1ME_Mouse1.21292126
67* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.20421019
68E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.19712928
69IGF1R_20145208_ChIP-Seq_DFB_Human1.16741560
70TP63_19390658_ChIP-ChIP_HaCaT_Human1.15856093
71RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.15076786
72* UTX_26944678_Chip-Seq_JUKART_Human1.14770186
73CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14352964
74MYC_22102868_ChIP-Seq_BL_Human1.10174393
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08024405
76VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.06405126
77GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05350548
78* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.04156084
79MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.03768063
80FOXP3_21729870_ChIP-Seq_TREG_Human1.03004694
81CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02980220
82* KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.00158642
83STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.99602714
84CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98345933
85NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.98032905
86SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.98007443
87VDR_23849224_ChIP-Seq_CD4+_Human0.98002643
88IRF1_19129219_ChIP-ChIP_H3396_Human0.97666666
89THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.96891243
90TAF15_26573619_Chip-Seq_HEK293_Human0.94551148
91PCGF2_27294783_Chip-Seq_NPCs_Mouse0.93749833
92MAF_26560356_Chip-Seq_TH2_Human0.92558167
93GATA3_26560356_Chip-Seq_TH1_Human0.92082185
94* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.91494950
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90820990
96WDR5_24793694_ChIP-Seq_LNCAP_Human0.90138576
97POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89106604
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89106604
99SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88686137
100GATA2_19941826_ChIP-Seq_K562_Human0.88682648
101* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88503989
102PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87894616
103TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.87488573
104NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.85288047
105EWS_26573619_Chip-Seq_HEK293_Human0.84002591
106GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78115266
107GATA1_19941826_ChIP-Seq_K562_Human0.76884474
108HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.76287920
109PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76079555
110PU.1_20513432_ChIP-Seq_Bcells_Mouse0.75878608
111PRDM14_20953172_ChIP-Seq_ESCs_Human0.75092485
112BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.73492997
113CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.71372990
114HOXB4_20404135_ChIP-ChIP_EML_Mouse0.70756931
115SMRT_27268052_Chip-Seq_Bcells_Human0.70613127
116CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.69536956
117* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.69305042
118* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.68968425
119ETS1_22383799_ChIP-Seq_G1ME_Mouse0.68422078
120E2F7_22180533_ChIP-Seq_HELA_Human0.66990819
121* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.66326318
122NFE2_27457419_Chip-Seq_LIVER_Mouse0.66296439
123EZH2_22144423_ChIP-Seq_EOC_Human0.66123681
124* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.65638120
125CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.65496157
126FLI1_27457419_Chip-Seq_LIVER_Mouse0.65412533
127RXR_22108803_ChIP-Seq_LS180_Human0.64540025
128PU1_27457419_Chip-Seq_LIVER_Mouse0.64405695
129P53_22387025_ChIP-Seq_ESCs_Mouse0.63339914
130PCGF2_27294783_Chip-Seq_ESCs_Mouse0.62928195
131EZH2_27294783_Chip-Seq_NPCs_Mouse0.62008309

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.83633548
2MP0005671_abnormal_response_to3.78180576
3MP0002148_abnormal_hypersensitivity_rea3.53381650
4MP0009785_altered_susceptibility_to3.43758743
5MP0000685_abnormal_immune_system3.29476658
6MP0005387_immune_system_phenotype3.24059993
7MP0001790_abnormal_immune_system3.24059993
8MP0003436_decreased_susceptibility_to3.15823198
9MP0005000_abnormal_immune_tolerance3.01875035
10MP0001800_abnormal_humoral_immune2.89478381
11MP0005025_abnormal_response_to2.83474942
12MP0002419_abnormal_innate_immunity2.82153963
13MP0003724_increased_susceptibility_to2.78685214
14MP0002452_abnormal_antigen_presenting2.75200437
15MP0002723_abnormal_immune_serum2.71014303
16MP0001819_abnormal_immune_cell2.55937834
17MP0002420_abnormal_adaptive_immunity2.54709934
18MP0004510_myositis2.46667404
19MP0002166_altered_tumor_susceptibility2.30591389
20MP0006082_CNS_inflammation2.27945854
21MP0002398_abnormal_bone_marrow2.25961341
22MP0002006_tumorigenesis2.22615296
23MP0005464_abnormal_platelet_physiology2.20090599
24MP0002396_abnormal_hematopoietic_system2.16989604
25MP0000716_abnormal_immune_system2.08669641
26MP0002405_respiratory_system_inflammati2.06375364
27MP0003763_abnormal_thymus_physiology2.05642872
28MP0005397_hematopoietic_system_phenotyp2.03962607
29MP0001545_abnormal_hematopoietic_system2.03962607
30MP0003303_peritoneal_inflammation2.00201399
31MP0000569_abnormal_digit_pigmentation1.94221715
32MP0001853_heart_inflammation1.89815302
33MP0008877_abnormal_DNA_methylation1.88187555
34MP0004808_abnormal_hematopoietic_stem1.76226002
35MP0005174_abnormal_tail_pigmentation1.75534129
36MP0000689_abnormal_spleen_morphology1.72826124
37MP0010155_abnormal_intestine_physiology1.72582186
38MP0005451_abnormal_body_composition1.71201337
39MP0001845_abnormal_inflammatory_respons1.71061285
40MP0002429_abnormal_blood_cell1.69362979
41MP0009764_decreased_sensitivity_to1.64445178
42MP0002722_abnormal_immune_system1.64089573
43MP0002138_abnormal_hepatobiliary_system1.62091180
44MP0005310_abnormal_salivary_gland1.60933950
45MP0003172_abnormal_lysosome_physiology1.48056108
46MP0008469_abnormal_protein_level1.44899272
47MP0001533_abnormal_skeleton_physiology1.42865197
48MP0000703_abnormal_thymus_morphology1.37877075
49MP0004947_skin_inflammation1.37329951
50MP0009278_abnormal_bone_marrow1.28410056
51MP0000015_abnormal_ear_pigmentation1.27252765
52MP0009333_abnormal_splenocyte_physiolog1.26870031
53MP0003183_abnormal_peptide_metabolism1.26239629
54MP0002139_abnormal_hepatobiliary_system1.25612980
55MP0003866_abnormal_defecation1.20565362
56MP0002132_abnormal_respiratory_system1.18971160
57MP0001873_stomach_inflammation1.18067413
58MP0003191_abnormal_cellular_cholesterol1.17230407
59MP0003448_altered_tumor_morphology1.16576593
60MP0000858_altered_metastatic_potential1.15625258
61MP0008004_abnormal_stomach_pH1.08590634
62MP0003787_abnormal_imprinting1.07476123
63MP0003075_altered_response_to1.01182317
64MP0000465_gastrointestinal_hemorrhage1.00612996
65MP0005075_abnormal_melanosome_morpholog0.98351073
66MP0008057_abnormal_DNA_replication0.97835779
67MP0002998_abnormal_bone_remodeling0.96094831
68MP0004147_increased_porphyrin_level0.95248092
69MP0002277_abnormal_respiratory_mucosa0.94817190
70MP0003943_abnormal_hepatobiliary_system0.93725818
71MP0002009_preneoplasia0.92232564
72MP0005058_abnormal_lysosome_morphology0.91001805
73MP0003195_calcinosis0.90868211
74MP0002163_abnormal_gland_morphology0.90691081
75MP0000490_abnormal_crypts_of0.89422939
76MP0001986_abnormal_taste_sensitivity0.89215754
77MP0002095_abnormal_skin_pigmentation0.88552434
78MP0003828_pulmonary_edema0.88472397
79MP0005647_abnormal_sex_gland0.87131980
80MP0003300_gastrointestinal_ulcer0.85663795
81MP0002876_abnormal_thyroid_physiology0.83693541
82MP0003656_abnormal_erythrocyte_physiolo0.81492929
83MP0004782_abnormal_surfactant_physiolog0.79856339
84MP0002933_joint_inflammation0.78457089
85MP0009763_increased_sensitivity_to0.76331224
86MP0004130_abnormal_muscle_cell0.74867603
87MP0000343_altered_response_to0.72589493
88MP0009697_abnormal_copulation0.71332623
89MP0008058_abnormal_DNA_repair0.69571685
90MP0003252_abnormal_bile_duct0.67629336
91MP0009115_abnormal_fat_cell0.66189481
92MP0001851_eye_inflammation0.65755684
93MP0001764_abnormal_homeostasis0.63811689
94MP0003693_abnormal_embryo_hatching0.63217680
95MP0008961_abnormal_basal_metabolism0.63144662
96MP0006054_spinal_hemorrhage0.61865048
97MP0005379_endocrine/exocrine_gland_phen0.61286823
98MP0001348_abnormal_lacrimal_gland0.60920354
99MP0003045_fibrosis0.60793124
100MP0000249_abnormal_blood_vessel0.60757038
101MP0004142_abnormal_muscle_tone0.60691331
102MP0002693_abnormal_pancreas_physiology0.60348060
103MP0001919_abnormal_reproductive_system0.59193933
104MP0008874_decreased_physiological_sensi0.58569783
105MP0003221_abnormal_cardiomyocyte_apopto0.58532513
106MP0005166_decreased_susceptibility_to0.58497959
107MP0004883_abnormal_blood_vessel0.57844807
108MP0002332_abnormal_exercise_endurance0.57606830
109MP0010094_abnormal_chromosome_stability0.57362862
110MP0005409_darkened_coat_color0.57222047
111MP0005266_abnormal_metabolism0.56714396
112MP0008007_abnormal_cellular_replicative0.56544767
113MP0002019_abnormal_tumor_incidence0.56302674
114MP0002735_abnormal_chemical_nociception0.56133304
115MP0000604_amyloidosis0.55151718
116MP0000371_diluted_coat_color0.54704385
117MP0001501_abnormal_sleep_pattern0.53728057
118MP0008260_abnormal_autophagy0.52482714
119MP0002653_abnormal_ependyma_morphology0.51771843
120MP0003690_abnormal_glial_cell0.51112609
121MP0002733_abnormal_thermal_nociception0.51041267
122MP0002254_reproductive_system_inflammat0.50888772
123MP0006292_abnormal_olfactory_placode0.50423969
124MP0005390_skeleton_phenotype0.49914023
125MP0003718_maternal_effect0.49391689
126MP0005076_abnormal_cell_differentiation0.47824275
127MP0009765_abnormal_xenobiotic_induced0.46944070
128MP0001663_abnormal_digestive_system0.46173690
129MP0002928_abnormal_bile_duct0.44654023

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.97228398
2Recurrent bacterial skin infections (HP:0005406)5.70783043
3Eczematoid dermatitis (HP:0000976)5.16784488
4Myositis (HP:0100614)4.53521186
5Optic neuritis (HP:0100653)4.36634756
6Retrobulbar optic neuritis (HP:0100654)4.36634756
7Mediastinal lymphadenopathy (HP:0100721)4.30864974
8Recurrent fungal infections (HP:0002841)4.24414741
9Recurrent viral infections (HP:0004429)4.15590690
10Recurrent gram-negative bacterial infections (HP:0005420)4.13173865
11Elevated erythrocyte sedimentation rate (HP:0003565)4.08392605
12Orchitis (HP:0100796)3.97009513
13Chronic otitis media (HP:0000389)3.90638520
14Recurrent skin infections (HP:0001581)3.69334184
15Autoimmune thrombocytopenia (HP:0001973)3.62138610
16Meningitis (HP:0001287)3.48153440
17Autoimmune hemolytic anemia (HP:0001890)3.46875697
18Periodontitis (HP:0000704)3.43876250
19Vasculitis (HP:0002633)3.42975948
20Abnormality of macrophages (HP:0004311)3.36241355
21Genetic anticipation (HP:0003743)3.34505295
22Panhypogammaglobulinemia (HP:0003139)3.33098749
23Gingivitis (HP:0000230)3.30546875
24Chronic mucocutaneous candidiasis (HP:0002728)3.22547015
25Recurrent cutaneous fungal infections (HP:0011370)3.22547015
26Increased IgM level (HP:0003496)3.22398172
27Petechiae (HP:0000967)3.17716269
28Chronic obstructive pulmonary disease (HP:0006510)3.14029886
29Obstructive lung disease (HP:0006536)3.14029886
30Abnormal delayed hypersensitivity skin test (HP:0002963)3.13139487
31Stomatitis (HP:0010280)3.07214242
32Pulmonary infiltrates (HP:0002113)3.04961143
33Agammaglobulinemia (HP:0004432)3.02841208
34Abnormality of the fingertips (HP:0001211)3.02183941
35Prolonged bleeding time (HP:0003010)2.99645804
36Acute lymphatic leukemia (HP:0006721)2.96939355
37IgM deficiency (HP:0002850)2.96592647
38Cellulitis (HP:0100658)2.93660061
39Recurrent bronchitis (HP:0002837)2.87314363
40Abnormality of T cell number (HP:0011839)2.81760133
41Thyroiditis (HP:0100646)2.81459032
42Stomach cancer (HP:0012126)2.78600125
43Abolished electroretinogram (ERG) (HP:0000550)2.76581241
44Keratoconjunctivitis sicca (HP:0001097)2.75370652
45Eosinophilia (HP:0001880)2.74449896
46Thrombocytosis (HP:0001894)2.72308875
47Arterial thrombosis (HP:0004420)2.70995474
48Encephalitis (HP:0002383)2.70636068
49Nasal polyposis (HP:0100582)2.65068451
50Hemoptysis (HP:0002105)2.65047736
51Gingival bleeding (HP:0000225)2.64195701
52T lymphocytopenia (HP:0005403)2.62817777
53Leukocytosis (HP:0001974)2.62107147
54IgG deficiency (HP:0004315)2.61484404
55Abnormality of the prostate (HP:0008775)2.54208885
56Epistaxis (HP:0000421)2.52866704
57Keratoconjunctivitis (HP:0001096)2.51893093
58Pustule (HP:0200039)2.51003276
59Hypoplasia of the thymus (HP:0000778)2.50035501
60Abnormality of B cell number (HP:0010975)2.49014010
61B lymphocytopenia (HP:0010976)2.49014010
62Abnormality of T cells (HP:0002843)2.47690706
63Hypergammaglobulinemia (HP:0010702)2.47253069
64Abnormality of eosinophils (HP:0001879)2.47142920
65Osteomyelitis (HP:0002754)2.47004897
66Recurrent pneumonia (HP:0006532)2.45088682
67Chronic sinusitis (HP:0011109)2.44631793
68Systemic lupus erythematosus (HP:0002725)2.44098801
69Alveolar cell carcinoma (HP:0006519)2.42802608
70Granulocytopenia (HP:0001913)2.42632429
71Slow saccadic eye movements (HP:0000514)2.40099295
72Inflammation of the large intestine (HP:0002037)2.37752516
73Basal ganglia calcification (HP:0002135)2.37228511
74Disinhibition (HP:0000734)2.36475239
75Increased neuronal autofluorescent lipopigment (HP:0002074)2.36258075
76Acute myeloid leukemia (HP:0004808)2.36136304
77Neoplasm of the tracheobronchial system (HP:0100552)2.32214060
78Interstitial pulmonary disease (HP:0006530)2.31634895
79Abnormality of the nasal mucosa (HP:0000433)2.29360243
80Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.28911349
81Lymphopenia (HP:0001888)2.28008867
82Abnormal hair whorl (HP:0010721)2.26228791
83Amaurosis fugax (HP:0100576)2.25059310
84Chronic diarrhea (HP:0002028)2.24301298
85Abnormality of cells of the lymphoid lineage (HP:0012140)2.23850893
86Vacuolated lymphocytes (HP:0001922)2.21839054
87Severe combined immunodeficiency (HP:0004430)2.19508063
88Gastrointestinal inflammation (HP:0004386)2.18936579
89Hematochezia (HP:0002573)2.17371362
90Prostate neoplasm (HP:0100787)2.16880690
91Gastrointestinal infarctions (HP:0005244)2.16518703
92Cheilitis (HP:0100825)2.15677109
93Urticaria (HP:0001025)2.14656430
94Chest pain (HP:0100749)2.14571345
95Abnormality of the columella (HP:0009929)2.12972312
96Abnormality of T cell physiology (HP:0011840)2.12956607
97IgA deficiency (HP:0002720)2.12347118
98Joint swelling (HP:0001386)2.12288214
99Increased cerebral lipofuscin (HP:0011813)2.11116788
100Recurrent lower respiratory tract infections (HP:0002783)2.10337561
101Gastrointestinal stroma tumor (HP:0100723)2.10253568
102Gangrene (HP:0100758)2.08362132
103Colitis (HP:0002583)2.07753342
104Gonadotropin excess (HP:0000837)2.07511350
105Recurrent sinusitis (HP:0011108)2.05895281
106Absent rod-and cone-mediated responses on ERG (HP:0007688)2.02925868
107Cellular immunodeficiency (HP:0005374)2.01586515
108Spontaneous hematomas (HP:0007420)2.01109523
109Impaired platelet aggregation (HP:0003540)1.99967597
110Abnormal platelet function (HP:0011869)1.99967597
111Clumsiness (HP:0002312)1.98687352
112Viral hepatitis (HP:0006562)1.94864022
113Keratitis (HP:0000491)1.90898912
114Progressive cerebellar ataxia (HP:0002073)1.90152527
115Abnormality of the heme biosynthetic pathway (HP:0010472)1.89519633
116Neutropenia (HP:0001875)1.88425575
117Increased IgE level (HP:0003212)1.87184148
118Urinary bladder sphincter dysfunction (HP:0002839)1.86585746
119Purpura (HP:0000979)1.86076249
120Combined immunodeficiency (HP:0005387)1.84290015
121Agnosia (HP:0010524)1.82569004
122Inappropriate behavior (HP:0000719)1.82458910
123Sepsis (HP:0100806)1.81550499
124Lymphoma (HP:0002665)1.80803863
125Polyneuropathy (HP:0001271)1.80135094
126Bronchitis (HP:0012387)1.75417164
127Colon cancer (HP:0003003)1.73049341
128Pulmonary embolism (HP:0002204)1.72899487
129Basal cell carcinoma (HP:0002671)1.72701871
130Aplasia/Hypoplasia of the thymus (HP:0010515)1.72303842

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK3.63689660
2MAP3K143.54091071
3MAP4K13.42077238
4RIPK43.10178025
5JAK33.05541453
6SIK33.05225989
7IRAK42.96305728
8BLK2.75504070
9TYK22.70942584
10TBK12.62610249
11IKBKE2.57447762
12FES2.35619717
13KIT2.30128998
14IKBKB2.19541553
15TEC2.06255511
16SYK2.00852301
17ZAP701.90490941
18BTK1.87940887
19DYRK31.82692206
20JAK11.76953152
21TAOK31.76809029
22MAP3K121.73458725
23NTRK31.63269026
24SIK21.62248738
25CHUK1.55753931
26IRAK31.54899587
27CAMKK21.53053063
28TRIM281.52537632
29CDK191.51680025
30HCK1.50237678
31TNIK1.49445752
32BMPR21.43485074
33MAP3K131.37032550
34FGR1.33937252
35MAP4K21.32280728
36ITK1.26278797
37TGFBR21.24463441
38LCK1.23975069
39YES11.22612584
40PIM21.20385972
41RPS6KA41.16779474
42CSF1R1.13360067
43PIM11.12566829
44LYN1.12490087
45FGFR31.12161960
46CDK121.08102553
47DYRK1B1.07805469
48MARK21.05919804
49MAP3K61.04295843
50BRD41.02590975
51PRPF4B1.01284240
52MAP2K71.00221667
53FGFR40.99255692
54CSK0.98092319
55TAOK10.96670344
56HIPK20.95817120
57JAK20.94914566
58MAP3K40.93563824
59GRK70.90998664
60MAP3K110.87761056
61STK100.87306723
62NEK90.86114850
63MAP2K30.82394674
64TESK20.81955515
65CDK40.81124142
66DAPK10.79866503
67STK40.79126630
68EIF2AK20.78263937
69TNK20.72836058
70EPHA40.72524002
71PRKCQ0.70160682
72FLT30.67187235
73IRAK10.66614070
74EPHA30.66436720
75CAMK40.64299719
76TRPM70.62964136
77MKNK10.62859664
78ERN10.62838782
79GRK50.62625990
80ZAK0.62397571
81MST40.61040791
82CDC70.60739300
83GRK60.60073907
84ATR0.59984805
85WNK30.59903199
86NLK0.59350769
87CDK30.59102088
88MATK0.59097888
89MKNK20.58961352
90DYRK1A0.55933699
91MAP3K50.55279886
92DYRK20.53565874
93ADRBK20.53506436
94CLK10.52175832
95FRK0.50585651
96TYRO30.49563385
97WNK10.48841983
98ERBB30.48801706
99PRKCD0.48442898
100CAMK1G0.48271842
101VRK10.47917230
102SGK20.47783219
103MARK30.47766351
104SGK30.47025184
105ALK0.46851599
106SGK2230.46678076
107SGK4940.46678076
108MAP3K70.46345497
109PDGFRB0.46330359
110MAPK70.46223451
111STK240.44235500
112PRKCH0.44213646
113RPS6KA60.43051606
114AKT30.42479783
115CAMK1D0.39799793
116BCKDK0.39754446
117DAPK20.36768137
118TAOK20.35075338
119MAPKAPK20.34241625
120NEK60.33184217
121MAP2K60.33143223
122TIE10.32158653
123EGFR0.31893286
124CASK0.31660856
125MAPK120.31364928
126NUAK10.31198302
127PDK10.30663544
128CDK90.30603679
129ABL10.30451894
130PIK3CG0.30167907
131RPS6KC10.28897926
132RPS6KL10.28897926
133EPHB10.27923680
134CDK60.26963333
135MUSK0.26893546
136STK160.26080400
137SGK10.25914554
138RPS6KA20.25742857
139CAMK10.25617885

Predicted pathways (KEGG)

RankGene SetZ-score
1Allograft rejection_Homo sapiens_hsa053303.08089219
2Leishmaniasis_Homo sapiens_hsa051402.91523150
3Primary immunodeficiency_Homo sapiens_hsa053402.71417555
4Intestinal immune network for IgA production_Homo sapiens_hsa046722.64129151
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.63831672
6Graft-versus-host disease_Homo sapiens_hsa053322.58005581
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.46538163
8Measles_Homo sapiens_hsa051622.41971868
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.37416327
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.28600472
11RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.27668885
12Osteoclast differentiation_Homo sapiens_hsa043802.23443487
13NOD-like receptor signaling pathway_Homo sapiens_hsa046212.19683339
14Type I diabetes mellitus_Homo sapiens_hsa049402.05053319
15B cell receptor signaling pathway_Homo sapiens_hsa046621.96404424
16Pertussis_Homo sapiens_hsa051331.89108793
17Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.86284678
18Hematopoietic cell lineage_Homo sapiens_hsa046401.79388833
19Staphylococcus aureus infection_Homo sapiens_hsa051501.77008116
20Influenza A_Homo sapiens_hsa051641.76499828
21Autoimmune thyroid disease_Homo sapiens_hsa053201.76183017
22Asthma_Homo sapiens_hsa053101.67935802
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.67019560
24Herpes simplex infection_Homo sapiens_hsa051681.65830255
25Tuberculosis_Homo sapiens_hsa051521.65140279
26TNF signaling pathway_Homo sapiens_hsa046681.62305672
27T cell receptor signaling pathway_Homo sapiens_hsa046601.58176548
28Rheumatoid arthritis_Homo sapiens_hsa053231.56537796
29Legionellosis_Homo sapiens_hsa051341.54843782
30Malaria_Homo sapiens_hsa051441.51396720
31Chemokine signaling pathway_Homo sapiens_hsa040621.51243280
32Toxoplasmosis_Homo sapiens_hsa051451.50566316
33Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.43178940
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.42801148
35African trypanosomiasis_Homo sapiens_hsa051431.38584204
36Hepatitis B_Homo sapiens_hsa051611.26056614
37Viral myocarditis_Homo sapiens_hsa054161.22798953
38Acute myeloid leukemia_Homo sapiens_hsa052211.22022716
39Salmonella infection_Homo sapiens_hsa051321.21365375
40Antigen processing and presentation_Homo sapiens_hsa046121.18561489
41Shigellosis_Homo sapiens_hsa051311.18146058
42Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16738628
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.16390921
44Apoptosis_Homo sapiens_hsa042101.14137356
45Transcriptional misregulation in cancer_Homo sapiens_hsa052021.05733786
46Glycosaminoglycan degradation_Homo sapiens_hsa005310.97409952
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90927754
48Platelet activation_Homo sapiens_hsa046110.90820866
49Other glycan degradation_Homo sapiens_hsa005110.90573699
50Phagosome_Homo sapiens_hsa041450.90180053
51Primary bile acid biosynthesis_Homo sapiens_hsa001200.89465882
52Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87329745
53Prolactin signaling pathway_Homo sapiens_hsa049170.85729066
54AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.84543853
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.82941967
56Hepatitis C_Homo sapiens_hsa051600.80735883
57SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80285103
58Caffeine metabolism_Homo sapiens_hsa002320.78489472
59Colorectal cancer_Homo sapiens_hsa052100.78297914
60Lysosome_Homo sapiens_hsa041420.75622004
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69260423
62Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.68611615
63Leukocyte transendothelial migration_Homo sapiens_hsa046700.68472355
64Chronic myeloid leukemia_Homo sapiens_hsa052200.68393620
65Type II diabetes mellitus_Homo sapiens_hsa049300.67505278
66Homologous recombination_Homo sapiens_hsa034400.65481316
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63927762
68Epstein-Barr virus infection_Homo sapiens_hsa051690.63789568
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62481098
70Pancreatic cancer_Homo sapiens_hsa052120.62423642
71Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.60375753
72Spliceosome_Homo sapiens_hsa030400.57694227
73Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.56643816
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53697860
75Non-homologous end-joining_Homo sapiens_hsa034500.49830761
76Basal transcription factors_Homo sapiens_hsa030220.49405839
77Retinol metabolism_Homo sapiens_hsa008300.48779384
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.46465892
79Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.46223723
80Renin-angiotensin system_Homo sapiens_hsa046140.45002588
81Morphine addiction_Homo sapiens_hsa050320.44680094
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.44655302
83Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.43914694
84MAPK signaling pathway_Homo sapiens_hsa040100.43781594
85RNA degradation_Homo sapiens_hsa030180.43188753
86HTLV-I infection_Homo sapiens_hsa051660.42468430
87Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.42200903
88Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41658080
89Fanconi anemia pathway_Homo sapiens_hsa034600.41628663
90Chemical carcinogenesis_Homo sapiens_hsa052040.41201356
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.39841704
92Taste transduction_Homo sapiens_hsa047420.39644347
93Inositol phosphate metabolism_Homo sapiens_hsa005620.38447463
94Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38287809
95Endometrial cancer_Homo sapiens_hsa052130.37287106
96Viral carcinogenesis_Homo sapiens_hsa052030.36802892
97Dorso-ventral axis formation_Homo sapiens_hsa043200.35459199
98Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34018931
99Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.33567472
100Collecting duct acid secretion_Homo sapiens_hsa049660.33142096
101Peroxisome_Homo sapiens_hsa041460.33116099
102Non-small cell lung cancer_Homo sapiens_hsa052230.32908953
103Amoebiasis_Homo sapiens_hsa051460.32860845
104Sphingolipid signaling pathway_Homo sapiens_hsa040710.32473914
105Regulation of autophagy_Homo sapiens_hsa041400.32377170
106RNA polymerase_Homo sapiens_hsa030200.30004751
107Insulin resistance_Homo sapiens_hsa049310.29646297
108MicroRNAs in cancer_Homo sapiens_hsa052060.29443655
109Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.29308499
110RNA transport_Homo sapiens_hsa030130.29279915
111mTOR signaling pathway_Homo sapiens_hsa041500.28573764
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.28455011
113FoxO signaling pathway_Homo sapiens_hsa040680.28426279
114Nicotine addiction_Homo sapiens_hsa050330.28275309
115VEGF signaling pathway_Homo sapiens_hsa043700.27442990
116Lysine degradation_Homo sapiens_hsa003100.27314700
117Prostate cancer_Homo sapiens_hsa052150.27257700
118Small cell lung cancer_Homo sapiens_hsa052220.26101088
119Regulation of actin cytoskeleton_Homo sapiens_hsa048100.25790517
120Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.25682379
121ErbB signaling pathway_Homo sapiens_hsa040120.24819243
122cAMP signaling pathway_Homo sapiens_hsa040240.24340669
123Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.23434661
124ABC transporters_Homo sapiens_hsa020100.23277649
125Carbohydrate digestion and absorption_Homo sapiens_hsa049730.23229770
126HIF-1 signaling pathway_Homo sapiens_hsa040660.22985319
127Notch signaling pathway_Homo sapiens_hsa043300.22638126
128Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.22596657
129Calcium signaling pathway_Homo sapiens_hsa040200.21132198

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