ATP5J2P6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1galactose catabolic process (GO:0019388)4.98491659
2positive regulation of male gonad development (GO:2000020)4.83419551
3signal peptide processing (GO:0006465)4.29946779
4negative chemotaxis (GO:0050919)4.25704621
5regulation of relaxation of muscle (GO:1901077)4.22941722
6neurotransmitter uptake (GO:0001504)4.19549402
7interferon-gamma production (GO:0032609)4.11782739
8negative regulation of execution phase of apoptosis (GO:1900118)4.05774115
9negative regulation of axon extension involved in axon guidance (GO:0048843)4.05265438
10neuromuscular process controlling posture (GO:0050884)4.04414627
11glucosamine-containing compound catabolic process (GO:1901072)4.04387698
12protein K6-linked ubiquitination (GO:0085020)3.95575507
13regulation of male gonad development (GO:2000018)3.87679178
14olfactory bulb development (GO:0021772)3.86354598
15alkaloid metabolic process (GO:0009820)3.61928735
16proteasome assembly (GO:0043248)3.56297710
17negative regulation of axon guidance (GO:1902668)3.42435539
18platelet dense granule organization (GO:0060155)3.42319764
19positive regulation of vesicle fusion (GO:0031340)3.40121346
20sterol biosynthetic process (GO:0016126)3.39644977
21positive regulation of mast cell activation (GO:0033005)3.39250393
22positive regulation of histone H3-K4 methylation (GO:0051571)3.37842563
23DNA demethylation (GO:0080111)3.35088627
24glycosphingolipid biosynthetic process (GO:0006688)3.32819290
25negative regulation of macroautophagy (GO:0016242)3.29362342
26oxidative demethylation (GO:0070989)3.29128259
27cholesterol biosynthetic process (GO:0006695)3.27559007
28regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)3.27216194
29fatty acid elongation (GO:0030497)3.27129196
30mannosylation (GO:0097502)3.17367816
31regulation of extracellular matrix disassembly (GO:0010715)3.13206862
32chaperone-mediated protein transport (GO:0072321)3.09099491
33transcription elongation from RNA polymerase III promoter (GO:0006385)3.07081093
34termination of RNA polymerase III transcription (GO:0006386)3.07081093
35DNA replication initiation (GO:0006270)3.05630321
36intracellular pH reduction (GO:0051452)3.02582205
37regulation of corticosteroid hormone secretion (GO:2000846)2.99630169
38positive regulation of developmental pigmentation (GO:0048087)2.99225554
39DNA double-strand break processing (GO:0000729)2.99105234
40angiogenesis involved in wound healing (GO:0060055)2.96135601
41protein heterotetramerization (GO:0051290)2.92776030
42regulation of telomerase activity (GO:0051972)2.91248989
43blood coagulation, intrinsic pathway (GO:0007597)2.91061627
44photoreceptor cell maintenance (GO:0045494)2.91053612
45regulation of transmission of nerve impulse (GO:0051969)2.90999457
46protein K11-linked deubiquitination (GO:0035871)2.87341793
47positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.86651496
48thrombin receptor signaling pathway (GO:0070493)2.85330674
49single strand break repair (GO:0000012)2.82418067
50cullin deneddylation (GO:0010388)2.79945458
51protein localization to Golgi apparatus (GO:0034067)2.79341659
52insulin secretion (GO:0030073)2.78608693
53regulation of glucocorticoid secretion (GO:2000849)2.77014283
54ganglion development (GO:0061548)2.76784364
55regulation of receptor biosynthetic process (GO:0010869)2.76101925
56transcription from RNA polymerase III promoter (GO:0006383)2.74982902
57heparin biosynthetic process (GO:0030210)2.74960864
58heparin metabolic process (GO:0030202)2.74960864
59positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.69799688
60histone H4 deacetylation (GO:0070933)2.67618512
61sialylation (GO:0097503)2.65465469
62deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.65238410
63negative regulation of T-helper cell differentiation (GO:0045623)2.64451395
64negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.64451395
65negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.63795219
66S-adenosylmethionine metabolic process (GO:0046500)2.63587416
67adaptation of signaling pathway (GO:0023058)2.62625830
68purine nucleobase biosynthetic process (GO:0009113)2.61589216
69endosome to melanosome transport (GO:0035646)2.60322444
70endosome to pigment granule transport (GO:0043485)2.60322444
71purine-containing compound salvage (GO:0043101)2.59839406
72peptidyl-histidine modification (GO:0018202)2.59351421
73terpenoid biosynthetic process (GO:0016114)2.58925676
74intestinal cholesterol absorption (GO:0030299)2.57070621
75ubiquinone metabolic process (GO:0006743)2.56960789
76peroxisome fission (GO:0016559)2.56783340
77negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.56639730
78DNA dealkylation (GO:0035510)2.56165600
79establishment of protein localization to mitochondrial membrane (GO:0090151)2.55624844
80ganglioside metabolic process (GO:0001573)2.55461137
81dopamine transport (GO:0015872)2.55088441
82intra-Golgi vesicle-mediated transport (GO:0006891)2.54248387
83DNA unwinding involved in DNA replication (GO:0006268)2.53250130
84galactose metabolic process (GO:0006012)2.51618674
85regulation of telomere maintenance via telomerase (GO:0032210)2.49989956
86negative regulation of telomere maintenance (GO:0032205)2.49860926
87histone mRNA metabolic process (GO:0008334)2.48620292
88neurofilament cytoskeleton organization (GO:0060052)2.47471968
89regulation of intracellular pH (GO:0051453)2.47140796
90regulation of cilium movement (GO:0003352)2.47125104
91ncRNA 3-end processing (GO:0043628)2.47083769
92inner mitochondrial membrane organization (GO:0007007)2.46207466
93regulation of steroid hormone secretion (GO:2000831)2.43409846
94regulation of homotypic cell-cell adhesion (GO:0034110)2.42922703
95purine nucleotide salvage (GO:0032261)2.40893251
96regulation of phospholipase A2 activity (GO:0032429)2.40633752
97response to X-ray (GO:0010165)2.40178534
98protein complex biogenesis (GO:0070271)2.38823211
99C-terminal protein amino acid modification (GO:0018410)2.35778404
100mitochondrial respiratory chain complex assembly (GO:0033108)2.34917581

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.71477444
2E2F7_22180533_ChIP-Seq_HELA_Human4.62847270
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.45092710
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.34312943
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.71538529
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.71311765
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.67201700
8TAF15_26573619_Chip-Seq_HEK293_Human2.63362555
9MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.41249350
10IRF1_19129219_ChIP-ChIP_H3396_Human2.34669795
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.32000238
12FUS_26573619_Chip-Seq_HEK293_Human2.19206823
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.18896280
14EWS_26573619_Chip-Seq_HEK293_Human2.17386992
15ELK1_19687146_ChIP-ChIP_HELA_Human2.07172738
16IGF1R_20145208_ChIP-Seq_DFB_Human2.03019775
17E2F4_17652178_ChIP-ChIP_JURKAT_Human2.00433027
18AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.97970670
19SMAD_19615063_ChIP-ChIP_OVARY_Human1.95499206
20EST1_17652178_ChIP-ChIP_JURKAT_Human1.91881179
21CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.89943936
22ZFP57_27257070_Chip-Seq_ESCs_Mouse1.85978076
23IRF8_22096565_ChIP-ChIP_GC-B_Human1.85872862
24IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.83754086
25DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.74867310
26STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.74459505
27P300_19829295_ChIP-Seq_ESCs_Human1.73802772
28HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68423231
29GBX2_23144817_ChIP-Seq_PC3_Human1.66558061
30IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.64196514
31CBP_20019798_ChIP-Seq_JUKART_Human1.64196514
32LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.60631873
33FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.58290861
34CREB1_15753290_ChIP-ChIP_HEK293T_Human1.46911885
35SMAD4_21799915_ChIP-Seq_A2780_Human1.44219599
36SCL_19346495_ChIP-Seq_HPC-7_Human1.42141235
37SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41921252
38ZNF274_21170338_ChIP-Seq_K562_Hela1.41479948
39PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.38474760
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.38412476
41UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.37055098
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36998466
43PIAS1_25552417_ChIP-Seq_VCAP_Human1.36754942
44SALL4_22934838_ChIP-ChIP_CD34+_Human1.35664841
45SRF_21415370_ChIP-Seq_HL-1_Mouse1.33862439
46PADI4_21655091_ChIP-ChIP_MCF-7_Human1.28954147
47RNF2_27304074_Chip-Seq_NSC_Mouse1.27641102
48VDR_23849224_ChIP-Seq_CD4+_Human1.27396279
49TP53_22573176_ChIP-Seq_HFKS_Human1.27181650
50FOXA1_27270436_Chip-Seq_PROSTATE_Human1.23245818
51FOXA1_25329375_ChIP-Seq_VCAP_Human1.23245818
52NANOG_19829295_ChIP-Seq_ESCs_Human1.23051790
53SOX2_19829295_ChIP-Seq_ESCs_Human1.23051790
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22889264
55EGR1_19374776_ChIP-ChIP_THP-1_Human1.22852181
56AR_20517297_ChIP-Seq_VCAP_Human1.22502775
57ER_23166858_ChIP-Seq_MCF-7_Human1.22304591
58AUTS2_25519132_ChIP-Seq_293T-REX_Human1.20991521
59MYC_18940864_ChIP-ChIP_HL60_Human1.20216315
60FOXA1_21572438_ChIP-Seq_LNCaP_Human1.19279988
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.17967615
62GATA3_21878914_ChIP-Seq_MCF-7_Human1.14754476
63AR_25329375_ChIP-Seq_VCAP_Human1.14684808
64FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.14590877
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14311384
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.14011633
67HIF1A_21447827_ChIP-Seq_MCF-7_Human1.13202442
68PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.12149837
69MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10365681
70CTBP1_25329375_ChIP-Seq_LNCAP_Human1.09778266
71MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.09712040
72HTT_18923047_ChIP-ChIP_STHdh_Human1.09205406
73TCF4_22108803_ChIP-Seq_LS180_Human1.08448214
74CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07478554
75STAT3_23295773_ChIP-Seq_U87_Human1.05674170
76SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.04896959
77FOXP3_21729870_ChIP-Seq_TREG_Human1.03858988
78PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03612797
79POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02999077
80TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02999077
81FLI1_21867929_ChIP-Seq_TH2_Mouse1.01967745
82FOXM1_26456572_ChIP-Seq_MCF-7_Human1.01658764
83PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01538613
84EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00185497
85EZH2_27294783_Chip-Seq_NPCs_Mouse0.99174983
86GATA3_26560356_Chip-Seq_TH2_Human0.99015345
87TAL1_26923725_Chip-Seq_HPCs_Mouse0.98476590
88AR_21572438_ChIP-Seq_LNCaP_Human0.96291748
89BCAT_22108803_ChIP-Seq_LS180_Human0.93668193
90IRF8_21731497_ChIP-ChIP_J774_Mouse0.92937522
91NR3C1_23031785_ChIP-Seq_PC12_Mouse0.92465427
92TP53_16413492_ChIP-PET_HCT116_Human0.92446324
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92055296
94CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.91499826
95PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.91258208
96SOX2_16153702_ChIP-ChIP_HESCs_Human0.91209233
97JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.90356336
98FLI1_27457419_Chip-Seq_LIVER_Mouse0.90081828
99NANOG_18555785_Chip-Seq_ESCs_Mouse0.89424711
100CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.88560424

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005084_abnormal_gallbladder_morpholo3.93291707
2MP0000015_abnormal_ear_pigmentation3.67999130
3MP0006276_abnormal_autonomic_nervous3.66742074
4MP0008004_abnormal_stomach_pH3.53133691
5MP0003195_calcinosis3.26407609
6MP0005464_abnormal_platelet_physiology2.99144124
7MP0010386_abnormal_urinary_bladder2.66338824
8MP0002396_abnormal_hematopoietic_system2.61891909
9MP0001529_abnormal_vocalization2.40472284
10MP0003880_abnormal_central_pattern2.37609097
11MP0000538_abnormal_urinary_bladder2.29134924
12MP0008007_abnormal_cellular_replicative2.25660884
13MP0006072_abnormal_retinal_apoptosis2.09009041
14MP0002638_abnormal_pupillary_reflex1.89690261
15MP0001727_abnormal_embryo_implantation1.86035883
16MP0003890_abnormal_embryonic-extraembry1.83202322
17MP0000569_abnormal_digit_pigmentation1.76890718
18MP0002095_abnormal_skin_pigmentation1.72274671
19MP0003656_abnormal_erythrocyte_physiolo1.71668157
20MP0004142_abnormal_muscle_tone1.67538647
21MP0008057_abnormal_DNA_replication1.65661985
22MP0010094_abnormal_chromosome_stability1.63068458
23MP0005253_abnormal_eye_physiology1.57181860
24MP0003122_maternal_imprinting1.55436416
25MP0008875_abnormal_xenobiotic_pharmacok1.54470361
26MP0003724_increased_susceptibility_to1.52845696
27MP0004510_myositis1.48996634
28MP0001986_abnormal_taste_sensitivity1.47780122
29MP0008995_early_reproductive_senescence1.46106704
30MP0003806_abnormal_nucleotide_metabolis1.38904254
31MP0003252_abnormal_bile_duct1.37402899
32MP0008058_abnormal_DNA_repair1.36699756
33MP0010329_abnormal_lipoprotein_level1.36300997
34MP0004084_abnormal_cardiac_muscle1.30023688
35MP0008877_abnormal_DNA_methylation1.29505379
36MP0003786_premature_aging1.28811268
37MP0008872_abnormal_physiological_respon1.27716893
38MP0004085_abnormal_heartbeat1.18163748
39MP0001835_abnormal_antigen_presentation1.17986815
40MP0001666_abnormal_nutrient_absorption1.15746301
41MP0005645_abnormal_hypothalamus_physiol1.15009647
42MP0003172_abnormal_lysosome_physiology1.13008883
43MP0005083_abnormal_biliary_tract1.12330820
44MP0005448_abnormal_energy_balance1.09858885
45MP0003943_abnormal_hepatobiliary_system1.09300600
46MP0005165_increased_susceptibility_to1.07723328
47MP0000465_gastrointestinal_hemorrhage1.07216892
48MP0004484_altered_response_of1.06371684
49MP0003075_altered_response_to1.06363459
50MP0003718_maternal_effect1.01525374
51MP0005646_abnormal_pituitary_gland0.99217908
52MP0005075_abnormal_melanosome_morpholog0.96573886
53MP0001502_abnormal_circadian_rhythm0.95202327
54MP0003121_genomic_imprinting0.95030467
55MP0002876_abnormal_thyroid_physiology0.93497756
56MP0001853_heart_inflammation0.93460289
57MP0003077_abnormal_cell_cycle0.93274542
58MP0002736_abnormal_nociception_after0.92307405
59MP0000778_abnormal_nervous_system0.90188813
60MP0002971_abnormal_brown_adipose0.88434241
61MP0002069_abnormal_eating/drinking_beha0.86413741
62MP0003787_abnormal_imprinting0.85743449
63MP0003111_abnormal_nucleus_morphology0.84080171
64MP0002653_abnormal_ependyma_morphology0.82920593
65MP0002909_abnormal_adrenal_gland0.80726508
66MP0001905_abnormal_dopamine_level0.80340096
67MP0005166_decreased_susceptibility_to0.77816011
68MP0009764_decreased_sensitivity_to0.76534124
69MP0009765_abnormal_xenobiotic_induced0.76509495
70MP0000372_irregular_coat_pigmentation0.74814924
71MP0005452_abnormal_adipose_tissue0.74633866
72MP0008932_abnormal_embryonic_tissue0.73734499
73MP0004808_abnormal_hematopoietic_stem0.72981921
74MP0002078_abnormal_glucose_homeostasis0.72741934
75MP0005174_abnormal_tail_pigmentation0.72058351
76MP0002751_abnormal_autonomic_nervous0.71802989
77MP0001324_abnormal_eye_pigmentation0.71215832
78MP0000689_abnormal_spleen_morphology0.70850468
79MP0005332_abnormal_amino_acid0.69627928
80MP0000358_abnormal_cell_content/0.69041116
81MP0002019_abnormal_tumor_incidence0.68740824
82MP0003953_abnormal_hormone_level0.68687021
83MP0001756_abnormal_urination0.68568505
84MP0005551_abnormal_eye_electrophysiolog0.67770845
85MP0009697_abnormal_copulation0.67391726
86MP0000230_abnormal_systemic_arterial0.67160154
87MP0000858_altered_metastatic_potential0.66432471
88MP0001764_abnormal_homeostasis0.64316890
89MP0009046_muscle_twitch0.64025503
90MP0002067_abnormal_sensory_capabilities0.63984213
91MP0002557_abnormal_social/conspecific_i0.63760983
92MP0009763_increased_sensitivity_to0.63750824
93MP0001984_abnormal_olfaction0.62626349
94MP0002398_abnormal_bone_marrow0.62405004
95MP0003868_abnormal_feces_composition0.62145601
96MP0002572_abnormal_emotion/affect_behav0.62004277
97MP0004957_abnormal_blastocyst_morpholog0.61826530
98MP0005367_renal/urinary_system_phenotyp0.61154625
99MP0000516_abnormal_urinary_system0.61154625
100MP0003221_abnormal_cardiomyocyte_apopto0.60700510

Predicted human phenotypes

RankGene SetZ-score
1Petechiae (HP:0000967)4.69333305
2Pancreatic islet-cell hyperplasia (HP:0004510)4.20140654
3Large for gestational age (HP:0001520)3.98105224
4Aplasia/Hypoplasia of the uvula (HP:0010293)3.94763836
5Gingival bleeding (HP:0000225)3.79123964
6Menorrhagia (HP:0000132)3.69323713
7Increased neuronal autofluorescent lipopigment (HP:0002074)3.69159862
8Prolonged bleeding time (HP:0003010)3.56586773
9Increased mean platelet volume (HP:0011877)3.46159023
10Abnormality of the ileum (HP:0001549)3.45666212
11Abnormality of the preputium (HP:0100587)3.41053386
12Albinism (HP:0001022)3.37974564
13Meckel diverticulum (HP:0002245)3.27372595
14Abnormal platelet volume (HP:0011876)3.26722127
15Pancreatic cysts (HP:0001737)3.08810716
16Oligodactyly (hands) (HP:0001180)3.06171748
17Agitation (HP:0000713)3.01922198
18Vacuolated lymphocytes (HP:0001922)3.00295915
19Hypothermia (HP:0002045)2.89658067
20Abnormality of chromosome stability (HP:0003220)2.88052101
21Increased cerebral lipofuscin (HP:0011813)2.85642719
22Abolished electroretinogram (ERG) (HP:0000550)2.79103112
23Septate vagina (HP:0001153)2.78891776
24Abnormal hair whorl (HP:0010721)2.74625130
25Hypoplastic pelvis (HP:0008839)2.74566387
26Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.73433512
27Intestinal atresia (HP:0011100)2.67345041
28Abnormality of endocrine pancreas physiology (HP:0012093)2.65372420
29Abnormality of the pancreatic islet cells (HP:0006476)2.65372420
30Purpura (HP:0000979)2.61173271
31True hermaphroditism (HP:0010459)2.54363892
32Papillary thyroid carcinoma (HP:0002895)2.53200506
33Abnormal platelet function (HP:0011869)2.38523578
34Impaired platelet aggregation (HP:0003540)2.38523578
35Epistaxis (HP:0000421)2.36377832
36Abnormality of the renal medulla (HP:0100957)2.35517419
37Clubbing of toes (HP:0100760)2.32804887
38Tubulointerstitial nephritis (HP:0001970)2.31702198
39Myelodysplasia (HP:0002863)2.18132708
40Postural tremor (HP:0002174)2.16775618
41Fatigue (HP:0012378)2.16663096
42Pancreatic fibrosis (HP:0100732)2.16542116
43Medial flaring of the eyebrow (HP:0010747)2.16307180
44Aplasia/Hypoplasia of the tongue (HP:0010295)2.15623819
45Bone marrow hypocellularity (HP:0005528)2.15017197
46Abnormality of the renal cortex (HP:0011035)2.13850033
47Neoplasm of the adrenal cortex (HP:0100641)2.13514594
48Lissencephaly (HP:0001339)2.13115699
49Prominent metopic ridge (HP:0005487)2.12986575
50Abnormal delayed hypersensitivity skin test (HP:0002963)2.12690879
51Hypoplastic female external genitalia (HP:0012815)2.11543284
52Retinal dysplasia (HP:0007973)2.09685847
53Duodenal stenosis (HP:0100867)2.07942107
54Small intestinal stenosis (HP:0012848)2.07942107
55Type II lissencephaly (HP:0007260)2.02932275
56Abnormality of the carotid arteries (HP:0005344)2.02513629
57Nephronophthisis (HP:0000090)1.99773626
58Tubulointerstitial abnormality (HP:0001969)1.99153687
59Thyroid carcinoma (HP:0002890)1.98582285
60Abnormality of midbrain morphology (HP:0002418)1.97418309
61Molar tooth sign on MRI (HP:0002419)1.97418309
62Labial hypoplasia (HP:0000066)1.97258362
63Prostate neoplasm (HP:0100787)1.95052803
64Abnormality of the duodenum (HP:0002246)1.93263101
65Ketoacidosis (HP:0001993)1.92956783
66Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.92231232
67Abnormal protein N-linked glycosylation (HP:0012347)1.92231232
68Abnormal protein glycosylation (HP:0012346)1.92231232
69Abnormal glycosylation (HP:0012345)1.92231232
70Cerebellar dysplasia (HP:0007033)1.91272426
71Volvulus (HP:0002580)1.90063348
72Epidermoid cyst (HP:0200040)1.87687621
73Spinal muscular atrophy (HP:0007269)1.86282789
74Occipital encephalocele (HP:0002085)1.84715768
75Absent speech (HP:0001344)1.83721585
76Oligodactyly (HP:0012165)1.80546923
77Abnormality of the metopic suture (HP:0005556)1.80466565
78Poor suck (HP:0002033)1.77059470
79Hepatocellular necrosis (HP:0001404)1.76806040
80Insulin-resistant diabetes mellitus (HP:0000831)1.76774229
81Congenital primary aphakia (HP:0007707)1.76360416
82Postnatal microcephaly (HP:0005484)1.76011789
83Generalized hypopigmentation (HP:0007513)1.75805792
84Acute myeloid leukemia (HP:0004808)1.74421951
85Congenital hepatic fibrosis (HP:0002612)1.74311123
86Inability to walk (HP:0002540)1.71507451
87Limb hypertonia (HP:0002509)1.68513423
88Fair hair (HP:0002286)1.67214673
89Pulmonary fibrosis (HP:0002206)1.66974064
90Chromosomal breakage induced by crosslinking agents (HP:0003221)1.66139830
91Gait imbalance (HP:0002141)1.65795591
92Choroideremia (HP:0001139)1.64879111
93Abnormality of male internal genitalia (HP:0000022)1.63647641
94Type I transferrin isoform profile (HP:0003642)1.63079283
95Febrile seizures (HP:0002373)1.61443883
96Anencephaly (HP:0002323)1.60193030
97Curly hair (HP:0002212)1.60183784
98Hemiparesis (HP:0001269)1.59850042
99Congenital malformation of the right heart (HP:0011723)1.58188079
100Double outlet right ventricle (HP:0001719)1.58188079

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST45.37762603
2GRK73.12297469
3MST1R2.89232736
4NUAK12.84432956
5WNK32.84377286
6STK38L2.60566392
7BCKDK2.54096370
8SIK32.34903798
9STK382.31883614
10TRIM282.31211322
11MAP3K42.14466925
12BMPR1B2.06147117
13STK161.89291441
14ERBB31.85033606
15FLT31.83614911
16MAPK131.82602542
17PKN11.77045499
18BRSK21.67397688
19ADRBK21.63807269
20EIF2AK31.63459918
21FRK1.61493057
22VRK21.58469822
23DAPK21.38870462
24STK101.35729483
25MET1.29118491
26IRAK21.29094579
27GRK11.23000617
28MAP4K21.17659905
29BMX1.17654502
30IRAK11.15671175
31CSF1R1.15631821
32AKT31.15273122
33TAOK31.13616972
34CDC71.12620705
35EPHA31.06110125
36SRPK11.05053846
37GRK51.04775700
38NEK11.04157543
39ADRBK11.02447416
40MAP2K71.01994694
41TAF11.01582920
42CAMK11.01266433
43BCR1.00560928
44TRPM70.99887306
45TEC0.96453462
46EIF2AK10.96194865
47TNK20.90242513
48PBK0.87363561
49OXSR10.86720088
50MKNK20.86034214
51CDK80.82996642
52PIK3CG0.82679997
53CSNK1G30.82591705
54DYRK20.81550419
55LMTK20.80791505
56KDR0.80760997
57EIF2AK20.77843868
58TGFBR20.76897807
59CSNK1A1L0.75385616
60MOS0.74360379
61VRK10.70974444
62DAPK10.65884448
63IKBKB0.65777358
64CSNK1G20.65146967
65SYK0.65110263
66PAK30.63508438
67ACVR1B0.63116359
68PLK20.62515168
69PTK2B0.61067349
70CSNK1G10.58883620
71STK40.55327242
72PLK30.54591797
73PRKAA20.54395521
74IGF1R0.52485399
75STK30.48492431
76ATR0.47223251
77BRAF0.45669835
78CHEK20.45104705
79PLK10.44419182
80MINK10.42876493
81PLK40.42534676
82TESK20.40507676
83PRKD20.39364936
84MKNK10.37993840
85RET0.37513096
86CLK10.36838019
87PDK10.35696549
88MAP3K120.32960171
89ATM0.31480721
90PRKCE0.31150599
91PIM20.30425718
92KSR10.29737086
93CAMK1G0.29531585
94SGK20.29343415
95TIE10.29264172
96TXK0.28499025
97INSRR0.26308931
98MAP3K70.26226219
99PRKACG0.25455568
100TESK10.25180366

Predicted pathways (KEGG)

RankGene SetZ-score
1Steroid biosynthesis_Homo sapiens_hsa001003.78206505
2DNA replication_Homo sapiens_hsa030303.43776150
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.16472690
4Fanconi anemia pathway_Homo sapiens_hsa034603.04897715
5Homologous recombination_Homo sapiens_hsa034402.97348229
6Mismatch repair_Homo sapiens_hsa034302.95152828
7Proteasome_Homo sapiens_hsa030502.73476568
8Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.67076273
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.36317813
10Protein export_Homo sapiens_hsa030602.36154145
11Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.31243921
12Sulfur metabolism_Homo sapiens_hsa009202.18150120
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.92090798
14Vitamin B6 metabolism_Homo sapiens_hsa007501.88523299
15Folate biosynthesis_Homo sapiens_hsa007901.85985907
16Oxidative phosphorylation_Homo sapiens_hsa001901.81153285
17Circadian rhythm_Homo sapiens_hsa047101.77468942
18Asthma_Homo sapiens_hsa053101.73385241
19Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.72446909
20Fat digestion and absorption_Homo sapiens_hsa049751.64413339
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.58916763
22Arachidonic acid metabolism_Homo sapiens_hsa005901.57181515
23Non-homologous end-joining_Homo sapiens_hsa034501.54863562
24Pancreatic secretion_Homo sapiens_hsa049721.43889820
25Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.39469109
26Parkinsons disease_Homo sapiens_hsa050121.39203385
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.37990604
28Base excision repair_Homo sapiens_hsa034101.31713304
29Olfactory transduction_Homo sapiens_hsa047401.31320021
30Fatty acid elongation_Homo sapiens_hsa000621.31045594
31Intestinal immune network for IgA production_Homo sapiens_hsa046721.29453126
32One carbon pool by folate_Homo sapiens_hsa006701.21085364
33N-Glycan biosynthesis_Homo sapiens_hsa005101.08430077
34Tryptophan metabolism_Homo sapiens_hsa003801.06421074
35Butanoate metabolism_Homo sapiens_hsa006501.04272741
36Glycerolipid metabolism_Homo sapiens_hsa005611.02817181
37Collecting duct acid secretion_Homo sapiens_hsa049660.98633002
38Rheumatoid arthritis_Homo sapiens_hsa053230.96932994
39Type I diabetes mellitus_Homo sapiens_hsa049400.94278355
40Maturity onset diabetes of the young_Homo sapiens_hsa049500.92507155
41Ether lipid metabolism_Homo sapiens_hsa005650.91510691
42Peroxisome_Homo sapiens_hsa041460.90807524
43Huntingtons disease_Homo sapiens_hsa050160.90040858
44Hematopoietic cell lineage_Homo sapiens_hsa046400.87393422
45Nucleotide excision repair_Homo sapiens_hsa034200.85263797
46Linoleic acid metabolism_Homo sapiens_hsa005910.84884844
47Platelet activation_Homo sapiens_hsa046110.83920636
48Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.83095175
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.81593823
50alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.80243107
51Nitrogen metabolism_Homo sapiens_hsa009100.79868358
52Alzheimers disease_Homo sapiens_hsa050100.78380546
53Phototransduction_Homo sapiens_hsa047440.77519474
54Spliceosome_Homo sapiens_hsa030400.70725263
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69055336
56Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69002990
57Glutathione metabolism_Homo sapiens_hsa004800.68461404
58Purine metabolism_Homo sapiens_hsa002300.68031126
59Sphingolipid metabolism_Homo sapiens_hsa006000.67944621
60Legionellosis_Homo sapiens_hsa051340.66702594
61Cell cycle_Homo sapiens_hsa041100.66352658
62SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66283478
63Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.64668207
64Fatty acid metabolism_Homo sapiens_hsa012120.64025177
65Viral myocarditis_Homo sapiens_hsa054160.62550605
66Allograft rejection_Homo sapiens_hsa053300.62083971
67Tuberculosis_Homo sapiens_hsa051520.60450686
68Primary bile acid biosynthesis_Homo sapiens_hsa001200.59351136
69Mineral absorption_Homo sapiens_hsa049780.57380035
70RNA degradation_Homo sapiens_hsa030180.56703711
71Metabolic pathways_Homo sapiens_hsa011000.55419599
72Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.52890991
73Insulin secretion_Homo sapiens_hsa049110.52788282
74Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51789465
75Autoimmune thyroid disease_Homo sapiens_hsa053200.50640465
76Cardiac muscle contraction_Homo sapiens_hsa042600.49119110
77RNA transport_Homo sapiens_hsa030130.47377658
78RNA polymerase_Homo sapiens_hsa030200.45300299
79Melanoma_Homo sapiens_hsa052180.45270087
80Basal transcription factors_Homo sapiens_hsa030220.44770015
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.44750477
82Staphylococcus aureus infection_Homo sapiens_hsa051500.44390098
83Graft-versus-host disease_Homo sapiens_hsa053320.41759300
84Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.41307497
85Synaptic vesicle cycle_Homo sapiens_hsa047210.41114422
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39910290
87Serotonergic synapse_Homo sapiens_hsa047260.39907463
88Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37918229
89Systemic lupus erythematosus_Homo sapiens_hsa053220.37277232
90Pyrimidine metabolism_Homo sapiens_hsa002400.35117419
91Salivary secretion_Homo sapiens_hsa049700.34503745
92Galactose metabolism_Homo sapiens_hsa000520.33409688
93Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.31924672
94Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.30968310
95Phagosome_Homo sapiens_hsa041450.30663201
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.30466897
97beta-Alanine metabolism_Homo sapiens_hsa004100.29106733
98Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.29024844
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.26785832
100Propanoate metabolism_Homo sapiens_hsa006400.26762004

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »