ATAD5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)5.07708193
2DNA unwinding involved in DNA replication (GO:0006268)5.04672196
3telomere maintenance via semi-conservative replication (GO:0032201)5.04174903
4replication fork processing (GO:0031297)4.95578520
5kinetochore organization (GO:0051383)4.90465408
6DNA strand elongation (GO:0022616)4.81798182
7maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.78788162
8protein localization to kinetochore (GO:0034501)4.73846730
9telomere maintenance via recombination (GO:0000722)4.63467731
10nuclear pore complex assembly (GO:0051292)4.61332264
11meiotic chromosome segregation (GO:0045132)4.57233708
12mitotic recombination (GO:0006312)4.55973553
13DNA replication initiation (GO:0006270)4.55924544
14nuclear pore organization (GO:0006999)4.42972528
15nucleotide-excision repair, DNA gap filling (GO:0006297)4.37729885
16kinetochore assembly (GO:0051382)4.34386382
17mitotic sister chromatid segregation (GO:0000070)4.31007628
18somatic hypermutation of immunoglobulin genes (GO:0016446)4.29861023
19somatic diversification of immune receptors via somatic mutation (GO:0002566)4.29861023
20regulation of centriole replication (GO:0046599)4.28543700
21mitotic sister chromatid cohesion (GO:0007064)4.25031057
22sister chromatid segregation (GO:0000819)4.24225943
23negative regulation of DNA-dependent DNA replication (GO:2000104)4.18355015
24DNA topological change (GO:0006265)4.18108444
25DNA replication checkpoint (GO:0000076)4.17138125
26positive regulation of mitotic sister chromatid separation (GO:1901970)4.15694295
27positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.15694295
28positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.15694295
29mitotic chromosome condensation (GO:0007076)4.13842820
30DNA replication-dependent nucleosome organization (GO:0034723)4.11885069
31DNA replication-dependent nucleosome assembly (GO:0006335)4.11885069
32regulation of sister chromatid cohesion (GO:0007063)4.06096492
33DNA strand renaturation (GO:0000733)4.01353555
34protein localization to chromosome, centromeric region (GO:0071459)3.98842856
35positive regulation of chromosome segregation (GO:0051984)3.97754949
36mitotic nuclear envelope disassembly (GO:0007077)3.97681900
37telomere maintenance via telomere lengthening (GO:0010833)3.93505446
38centriole replication (GO:0007099)3.85866086
39DNA duplex unwinding (GO:0032508)3.84672310
40DNA geometric change (GO:0032392)3.84546480
41dosage compensation (GO:0007549)3.79860309
42chromatin remodeling at centromere (GO:0031055)3.77990857
43mitotic metaphase plate congression (GO:0007080)3.76404947
44DNA double-strand break processing (GO:0000729)3.75632400
45CENP-A containing nucleosome assembly (GO:0034080)3.73857669
46membrane disassembly (GO:0030397)3.68574263
47nuclear envelope disassembly (GO:0051081)3.68574263
48synapsis (GO:0007129)3.66853512
49attachment of spindle microtubules to kinetochore (GO:0008608)3.64901572
50regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.61602018
51pore complex assembly (GO:0046931)3.61485365
52DNA replication-independent nucleosome organization (GO:0034724)3.60375442
53DNA replication-independent nucleosome assembly (GO:0006336)3.60375442
54formation of translation preinitiation complex (GO:0001731)3.59218992
55regulation of double-strand break repair via homologous recombination (GO:0010569)3.55810981
56mitotic G2/M transition checkpoint (GO:0044818)3.54523255
57base-excision repair (GO:0006284)3.53272318
58regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.51863320
59negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.51271581
60regulation of RNA export from nucleus (GO:0046831)3.50573975
61metaphase plate congression (GO:0051310)3.48474152
62purine nucleobase biosynthetic process (GO:0009113)3.43883885
63regulation of centrosome cycle (GO:0046605)3.43048759
64regulation of histone H3-K9 methylation (GO:0051570)3.40848384
65recombinational repair (GO:0000725)3.40720824
66embryonic process involved in female pregnancy (GO:0060136)3.40402337
67double-strand break repair via homologous recombination (GO:0000724)3.39728605
68negative regulation of mitotic sister chromatid separation (GO:2000816)3.39482975
69negative regulation of sister chromatid segregation (GO:0033046)3.39482975
70negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.39482975
71negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.39482975
72negative regulation of mitotic sister chromatid segregation (GO:0033048)3.39482975
73negative regulation of DNA recombination (GO:0045910)3.37704079
74regulation of double-strand break repair (GO:2000779)3.37109743
75mitotic spindle checkpoint (GO:0071174)3.36693779
76postreplication repair (GO:0006301)3.36452913
77regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.34924638
78regulation of mitotic spindle checkpoint (GO:1903504)3.34924638
79mismatch repair (GO:0006298)3.34882176
80nucleobase biosynthetic process (GO:0046112)3.33934371
81chromosome segregation (GO:0007059)3.33799729
82protein K6-linked ubiquitination (GO:0085020)3.32500638
83chromatin assembly or disassembly (GO:0006333)3.32246605
84DNA deamination (GO:0045006)3.32204313
85viral mRNA export from host cell nucleus (GO:0046784)3.30766485
86DNA conformation change (GO:0071103)3.29983937
87DNA ligation (GO:0006266)3.25336437
88telomere maintenance (GO:0000723)3.25256121
89microtubule depolymerization (GO:0007019)3.24574313
90establishment of chromosome localization (GO:0051303)3.24007431
91negative regulation of mRNA processing (GO:0050686)3.23724260
92ATP-dependent chromatin remodeling (GO:0043044)3.23031669
93IMP biosynthetic process (GO:0006188)3.22907839
94telomere organization (GO:0032200)3.21909967
95spindle assembly checkpoint (GO:0071173)3.21688021
96mitotic spindle assembly checkpoint (GO:0007094)3.20739944
97regulation of spindle organization (GO:0090224)3.20607309
98pre-miRNA processing (GO:0031054)3.20284340
99resolution of meiotic recombination intermediates (GO:0000712)3.19409184
100regulation of nuclear cell cycle DNA replication (GO:0033262)3.18759394
101termination of RNA polymerase II transcription (GO:0006369)3.18534110
102negative regulation of RNA splicing (GO:0033119)3.16341548
103regulation of mitotic metaphase/anaphase transition (GO:0030071)3.16283658
104intra-S DNA damage checkpoint (GO:0031573)3.15689214
105regulation of centrosome duplication (GO:0010824)3.15498999
106negative regulation of chromosome segregation (GO:0051985)3.15375776
107histone exchange (GO:0043486)3.14813264
108regulation of chromosome segregation (GO:0051983)3.14263356
109spliceosomal tri-snRNP complex assembly (GO:0000244)3.14047058
110proline biosynthetic process (GO:0006561)3.14022034
111translesion synthesis (GO:0019985)3.11623403
112regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.11021877
113regulation of DNA endoreduplication (GO:0032875)3.10075832
114non-recombinational repair (GO:0000726)3.09660093
115double-strand break repair via nonhomologous end joining (GO:0006303)3.09660093
116regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.09386571
117regulation of DNA damage checkpoint (GO:2000001)3.08085356
118chromatin assembly (GO:0031497)3.07422699
119mitotic G1 DNA damage checkpoint (GO:0031571)3.07109105
120centrosome organization (GO:0051297)3.05919745
121sister chromatid cohesion (GO:0007062)3.05545188
122spindle checkpoint (GO:0031577)3.02702955
123DNA catabolic process, exonucleolytic (GO:0000738)3.02696560
124regulation of sister chromatid segregation (GO:0033045)3.01005808
125regulation of mitotic sister chromatid separation (GO:0010965)3.01005808
126regulation of mitotic sister chromatid segregation (GO:0033047)3.01005808
127somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.99787734
128somatic cell DNA recombination (GO:0016444)2.99787734
129protein localization to chromosome (GO:0034502)2.99685198
130negative regulation of histone methylation (GO:0031061)2.99121237
131nuclear envelope organization (GO:0006998)2.98278240

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.45027239
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.56437942
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.57004006
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.53183779
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.75816450
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.59878734
7E2F1_21310950_ChIP-Seq_MCF-7_Human2.54383706
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.45898210
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.35428382
10* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.34636220
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.22961322
12AR_21909140_ChIP-Seq_LNCAP_Human2.16013928
13NELFA_20434984_ChIP-Seq_ESCs_Mouse2.09896447
14MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.01617246
15E2F7_22180533_ChIP-Seq_HELA_Human11.7005487
16SALL1_21062744_ChIP-ChIP_HESCs_Human1.96787799
17SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.92631402
18MYC_22102868_ChIP-Seq_BL_Human1.92318478
19EST1_17652178_ChIP-ChIP_JURKAT_Human1.87699418
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.87500755
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.85742027
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.84455129
23EWS_26573619_Chip-Seq_HEK293_Human1.84349341
24MYCN_18555785_ChIP-Seq_MESCs_Mouse1.82172378
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.81887514
26XRN2_22483619_ChIP-Seq_HELA_Human1.72453911
27MYC_18940864_ChIP-ChIP_HL60_Human1.69523366
28FUS_26573619_Chip-Seq_HEK293_Human1.69379688
29TP63_19390658_ChIP-ChIP_HaCaT_Human1.68692331
30ETS1_20019798_ChIP-Seq_JURKAT_Human1.68237322
31VDR_23849224_ChIP-Seq_CD4+_Human1.65615521
32ZNF274_21170338_ChIP-Seq_K562_Hela1.65609265
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.64396112
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.61914455
35* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.59816823
36HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.57871009
37CREB1_15753290_ChIP-ChIP_HEK293T_Human1.55825783
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.54306275
39* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.50995024
40TTF2_22483619_ChIP-Seq_HELA_Human1.49062631
41VDR_21846776_ChIP-Seq_THP-1_Human1.47422534
42* FOXP3_21729870_ChIP-Seq_TREG_Human1.47010418
43YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46656655
44IRF1_19129219_ChIP-ChIP_H3396_Human1.46448782
45RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46074788
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45552752
47GABP_17652178_ChIP-ChIP_JURKAT_Human1.45326596
48KDM5A_27292631_Chip-Seq_BREAST_Human1.43684632
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.41255309
50ELK1_19687146_ChIP-ChIP_HELA_Human1.38926903
51DCP1A_22483619_ChIP-Seq_HELA_Human1.38420345
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38124867
53GABP_19822575_ChIP-Seq_HepG2_Human1.36479627
54CIITA_25753668_ChIP-Seq_RAJI_Human1.35945593
55ESR1_15608294_ChIP-ChIP_MCF-7_Human1.34798394
56VDR_22108803_ChIP-Seq_LS180_Human1.34657510
57IGF1R_20145208_ChIP-Seq_DFB_Human1.34139948
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.33838448
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.33356860
60DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.33342802
61POU3F2_20337985_ChIP-ChIP_501MEL_Human1.33271176
62TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.29934678
63HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.29502708
64* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27540511
65ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.26744534
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26443060
67ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.25331587
68KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.24826819
69KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.24826819
70KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.24826819
71POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.23093731
72CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.22465263
73ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.20592084
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.20046842
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19308227
76NANOG_21062744_ChIP-ChIP_HESCs_Human1.19267701
77SOX2_16153702_ChIP-ChIP_HESCs_Human1.18651563
78STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18017932
79GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17948068
80SRF_21415370_ChIP-Seq_HL-1_Mouse1.17728154
81HOXB4_20404135_ChIP-ChIP_EML_Mouse1.17689153
82ELF1_17652178_ChIP-ChIP_JURKAT_Human1.13919811
83FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.10554974
84NANOG_16153702_ChIP-ChIP_HESCs_Human1.07182456
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.06730779
86TCF3_18692474_ChIP-Seq_MESCs_Mouse1.05046160
87HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.04727974
88FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.04583477
89KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.04100173
90TFEB_21752829_ChIP-Seq_HELA_Human1.04040950
91E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02739766
92SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02595094
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02502546
94YY1_21170310_ChIP-Seq_MESCs_Mouse1.02049898
95TAF15_26573619_Chip-Seq_HEK293_Human1.01566369
96NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.00577428
97PADI4_21655091_ChIP-ChIP_MCF-7_Human0.98547057
98NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.97877088
99RBPJ_22232070_ChIP-Seq_NCS_Mouse0.97217643
100CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.96536586
101ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95970192
102TCF3_18692474_ChIP-Seq_MEFs_Mouse0.95114879
103* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95105873
104CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.94678288
105SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.94633574
106FLI1_27457419_Chip-Seq_LIVER_Mouse0.94096111
107NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.93878692
108SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.93545011
109CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92247707
110HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.92153157
111STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.89627781
112SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.88220188
113BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.87224633
114* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.85571866
115GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83854414
116PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.83701406
117NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.83697097
118P300_19829295_ChIP-Seq_ESCs_Human0.81690701
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.81496471
120BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.79915675
121SPI1_23547873_ChIP-Seq_NB4_Human0.79590697
122MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.78347611
123PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.77978749
124EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.74818181
125CTBP1_25329375_ChIP-Seq_LNCAP_Human0.71765693
126ER_23166858_ChIP-Seq_MCF-7_Human0.70720640
127CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.67907928
128CTBP2_25329375_ChIP-Seq_LNCAP_Human0.67832806
129RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.66346496
130TP53_22573176_ChIP-Seq_HFKS_Human0.66186830
131ZFP57_27257070_Chip-Seq_ESCs_Mouse0.65786790
132GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.65155952
133SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.64011266
134CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.62211599
135SOX9_26525672_Chip-Seq_HEART_Mouse0.61453889
136* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.60636746
137FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.59830397

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.75031041
2MP0010094_abnormal_chromosome_stability4.94683368
3MP0003111_abnormal_nucleus_morphology4.07032008
4MP0003693_abnormal_embryo_hatching4.05041340
5MP0003077_abnormal_cell_cycle3.56463406
6MP0004957_abnormal_blastocyst_morpholog3.49136618
7MP0008058_abnormal_DNA_repair3.09321830
8MP0002396_abnormal_hematopoietic_system2.68028184
9MP0010352_gastrointestinal_tract_polyps2.48086195
10MP0008877_abnormal_DNA_methylation2.39533775
11MP0009697_abnormal_copulation2.37665321
12MP0008932_abnormal_embryonic_tissue2.36241798
13MP0010307_abnormal_tumor_latency2.33631524
14MP0000350_abnormal_cell_proliferation2.15890326
15MP0008007_abnormal_cellular_replicative2.13896198
16MP0009278_abnormal_bone_marrow2.11166048
17MP0001730_embryonic_growth_arrest2.07209284
18MP0003890_abnormal_embryonic-extraembry2.05142246
19MP0005076_abnormal_cell_differentiation1.98471099
20MP0003786_premature_aging1.86667092
21MP0004147_increased_porphyrin_level1.86249227
22MP0001697_abnormal_embryo_size1.82096306
23MP0002009_preneoplasia1.80828016
24MP0005380_embryogenesis_phenotype1.79113962
25MP0001672_abnormal_embryogenesis/_devel1.79113962
26MP0000490_abnormal_crypts_of1.77205396
27MP0005397_hematopoietic_system_phenotyp1.74969228
28MP0001545_abnormal_hematopoietic_system1.74969228
29MP0010030_abnormal_orbit_morphology1.73088524
30MP0004197_abnormal_fetal_growth/weight/1.72670539
31MP0002084_abnormal_developmental_patter1.71540801
32MP0002086_abnormal_extraembryonic_tissu1.69162044
33MP0003123_paternal_imprinting1.68430039
34MP0002085_abnormal_embryonic_tissue1.65396679
35MP0003984_embryonic_growth_retardation1.55982568
36MP0003136_yellow_coat_color1.54842345
37MP0000372_irregular_coat_pigmentation1.52586621
38MP0003567_abnormal_fetal_cardiomyocyte1.51946801
39MP0002088_abnormal_embryonic_growth/wei1.51592796
40MP0003121_genomic_imprinting1.50943375
41MP0001293_anophthalmia1.48487408
42MP0002080_prenatal_lethality1.45318472
43MP0002019_abnormal_tumor_incidence1.42023498
44MP0004808_abnormal_hematopoietic_stem1.39901931
45MP0000313_abnormal_cell_death1.33759218
46MP0002102_abnormal_ear_morphology1.32958382
47MP0005174_abnormal_tail_pigmentation1.32454300
48MP0005171_absent_coat_pigmentation1.19385147
49MP0008789_abnormal_olfactory_epithelium1.16485849
50MP0000703_abnormal_thymus_morphology1.13382230
51MP0002166_altered_tumor_susceptibility1.11570831
52MP0004233_abnormal_muscle_weight1.10359412
53MP0003119_abnormal_digestive_system1.07320389
54MP0002160_abnormal_reproductive_system1.07053903
55MP0000631_abnormal_neuroendocrine_gland1.06148486
56MP0002234_abnormal_pharynx_morphology1.05585882
57MP0002006_tumorigenesis1.04668188
58MP0003698_abnormal_male_reproductive1.04628662
59MP0002398_abnormal_bone_marrow1.03192455
60MP0008995_early_reproductive_senescence1.02824779
61MP0003763_abnormal_thymus_physiology1.02761574
62MP0002210_abnormal_sex_determination1.00278553
63MP0003787_abnormal_imprinting1.00153643
64MP0000015_abnormal_ear_pigmentation0.99530888
65MP0000569_abnormal_digit_pigmentation0.98590216
66MP0001145_abnormal_male_reproductive0.97158485
67MP0009703_decreased_birth_body0.96686493
68MP0005499_abnormal_olfactory_system0.96355803
69MP0005394_taste/olfaction_phenotype0.96355803
70MP0001529_abnormal_vocalization0.95586638
71MP0005253_abnormal_eye_physiology0.95546503
72MP0006035_abnormal_mitochondrial_morpho0.95376681
73MP0002233_abnormal_nose_morphology0.95046810
74MP0000689_abnormal_spleen_morphology0.93228266
75MP0002722_abnormal_immune_system0.91593011
76MP0002111_abnormal_tail_morphology0.91472924
77MP0004264_abnormal_extraembryonic_tissu0.88128196
78MP0000371_diluted_coat_color0.86811172
79MP0002075_abnormal_coat/hair_pigmentati0.86087320
80MP0005391_vision/eye_phenotype0.85982286
81MP0003315_abnormal_perineum_morphology0.84364008
82MP0003718_maternal_effect0.84125264
83MP0009333_abnormal_splenocyte_physiolog0.84097924
84MP0003935_abnormal_craniofacial_develop0.83992112
85MP0002095_abnormal_skin_pigmentation0.83981229
86MP0003937_abnormal_limbs/digits/tail_de0.81674099
87MP0000566_synostosis0.81252339
88MP0000647_abnormal_sebaceous_gland0.81189187
89MP0001929_abnormal_gametogenesis0.80863425
90MP0000653_abnormal_sex_gland0.80834722
91MP0003861_abnormal_nervous_system0.80623983
92MP0004133_heterotaxia0.80540280
93MP0005075_abnormal_melanosome_morpholog0.78296542
94MP0000427_abnormal_hair_cycle0.78240283
95MP0005389_reproductive_system_phenotype0.78239802
96MP0009053_abnormal_anal_canal0.78221406
97MP0000432_abnormal_head_morphology0.77677205
98MP0002751_abnormal_autonomic_nervous0.77358949
99MP0001188_hyperpigmentation0.75499783
100MP0001346_abnormal_lacrimal_gland0.74466812
101MP0003705_abnormal_hypodermis_morpholog0.74199061
102MP0001119_abnormal_female_reproductive0.72382094
103MP0002092_abnormal_eye_morphology0.72380778
104MP0000049_abnormal_middle_ear0.71217045
105MP0002249_abnormal_larynx_morphology0.71210303
106MP0002161_abnormal_fertility/fecundity0.71011775
107MP0001186_pigmentation_phenotype0.70640750
108MP0002282_abnormal_trachea_morphology0.70636069
109MP0003755_abnormal_palate_morphology0.69971258
110MP0001915_intracranial_hemorrhage0.69696698
111MP0005551_abnormal_eye_electrophysiolog0.69634824
112MP0006292_abnormal_olfactory_placode0.69136099
113MP0002938_white_spotting0.68435083
114MP0000358_abnormal_cell_content/0.68306766
115MP0002429_abnormal_blood_cell0.68059470
116MP0003699_abnormal_female_reproductive0.67932916
117MP0002925_abnormal_cardiovascular_devel0.67245732
118MP0002114_abnormal_axial_skeleton0.66948496
119MP0009672_abnormal_birth_weight0.66924719
120MP0005023_abnormal_wound_healing0.65317861
121MP0006036_abnormal_mitochondrial_physio0.64847187
122MP0001485_abnormal_pinna_reflex0.64739325
123MP0005621_abnormal_cell_physiology0.64464019
124MP0001286_abnormal_eye_development0.64329789
125MP0003943_abnormal_hepatobiliary_system0.63965143
126MP0002697_abnormal_eye_size0.63822182
127MP0005187_abnormal_penis_morphology0.63562533
128MP0005384_cellular_phenotype0.63315140
129MP0002405_respiratory_system_inflammati0.63203395
130MP0006072_abnormal_retinal_apoptosis0.62064315
131MP0000477_abnormal_intestine_morphology0.61111230
132MP0008770_decreased_survivor_rate0.60193729
133MP0002932_abnormal_joint_morphology0.59759714
134MP0003938_abnormal_ear_development0.59162635
135MP0005646_abnormal_pituitary_gland0.58877915
136MP0000716_abnormal_immune_system0.58342251
137MP0000428_abnormal_craniofacial_morphol0.57425934

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.04580430
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.80381740
3Volvulus (HP:0002580)4.28049288
4Abnormality of chromosome stability (HP:0003220)3.70034994
5Birth length less than 3rd percentile (HP:0003561)3.69613011
6Medulloblastoma (HP:0002885)3.52780109
7Facial hemangioma (HP:0000329)3.49909270
8Abnormality of the ileum (HP:0001549)3.44265291
9Hypochromic microcytic anemia (HP:0004840)3.25924310
10Rib fusion (HP:0000902)3.23817716
11Aplasia/Hypoplasia of the uvula (HP:0010293)3.21568034
12Patellar aplasia (HP:0006443)3.19452959
13Meckel diverticulum (HP:0002245)3.15021280
14Selective tooth agenesis (HP:0001592)3.14857319
15Abnormality of the preputium (HP:0100587)3.04891204
16Colon cancer (HP:0003003)3.02908888
17Ependymoma (HP:0002888)3.00013030
18Abnormality of the labia minora (HP:0012880)2.96505653
19Absent radius (HP:0003974)2.95461316
20Aplasia/Hypoplasia of the patella (HP:0006498)2.92520092
21Myelodysplasia (HP:0002863)2.90857891
22Basal cell carcinoma (HP:0002671)2.86885242
23Abnormal number of incisors (HP:0011064)2.85569281
24Absent forearm bone (HP:0003953)2.75645732
25Aplasia involving forearm bones (HP:0009822)2.75645732
26Nephroblastoma (Wilms tumor) (HP:0002667)2.72950990
27Absent thumb (HP:0009777)2.70882383
28Ectopic kidney (HP:0000086)2.68290284
29Neoplasm of the oral cavity (HP:0100649)2.66694443
30Poikiloderma (HP:0001029)2.66660111
31Breast hypoplasia (HP:0003187)2.65762946
32Squamous cell carcinoma (HP:0002860)2.65345850
33Abnormality of the astrocytes (HP:0100707)2.60166160
34Astrocytoma (HP:0009592)2.60166160
35Rhabdomyosarcoma (HP:0002859)2.59974313
36Small intestinal stenosis (HP:0012848)2.55673443
37Duodenal stenosis (HP:0100867)2.55673443
38Agnosia (HP:0010524)2.55601947
39Embryonal renal neoplasm (HP:0011794)2.54620386
40Short thumb (HP:0009778)2.54445349
41Impulsivity (HP:0100710)2.53473317
42Acute lymphatic leukemia (HP:0006721)2.47640273
43Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.47281354
44Short 4th metacarpal (HP:0010044)2.47281354
45Increased nuchal translucency (HP:0010880)2.43853256
46Rectal fistula (HP:0100590)2.41765465
47Rectovaginal fistula (HP:0000143)2.41765465
48Intestinal fistula (HP:0100819)2.41594026
49Glioma (HP:0009733)2.39007635
50Prominent nose (HP:0000448)2.37246137
51Reticulocytopenia (HP:0001896)2.36776074
52Abnormality of the fingertips (HP:0001211)2.36179225
53Abnormality of the carotid arteries (HP:0005344)2.36151404
54Premature graying of hair (HP:0002216)2.35296830
55Cafe-au-lait spot (HP:0000957)2.30692437
56Aplasia/hypoplasia of the humerus (HP:0006507)2.30090935
57Intestinal atresia (HP:0011100)2.26832690
58Short humerus (HP:0005792)2.26206455
59Proximal placement of thumb (HP:0009623)2.21938669
60Clubbing of toes (HP:0100760)2.20916015
61Deviation of the thumb (HP:0009603)2.17184504
62Cortical dysplasia (HP:0002539)2.16768307
63Abnormality of the duodenum (HP:0002246)2.14491460
64Abnormality of DNA repair (HP:0003254)2.13890529
65Abnormality of cochlea (HP:0000375)2.11974033
66Aplastic anemia (HP:0001915)2.08944819
67Sloping forehead (HP:0000340)2.08258404
68Aplasia/Hypoplasia of the sacrum (HP:0008517)2.08008850
69Abnormality of the pons (HP:0007361)2.07719214
70Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.06991852
71Hypochromic anemia (HP:0001931)2.06878908
72Horseshoe kidney (HP:0000085)2.05141533
73Neoplasm of striated muscle (HP:0009728)2.04665961
74Duplicated collecting system (HP:0000081)2.02809736
75Pancreatic fibrosis (HP:0100732)2.01729723
76Bone marrow hypocellularity (HP:0005528)2.01110990
77Arteriovenous malformation (HP:0100026)1.96732666
78Acute myeloid leukemia (HP:0004808)1.96619616
79Hypoplasia of the pons (HP:0012110)1.95854069
80Tracheoesophageal fistula (HP:0002575)1.94652674
81Atresia of the external auditory canal (HP:0000413)1.94078624
82Supernumerary spleens (HP:0009799)1.92378624
83Ulnar bowing (HP:0003031)1.91172128
84Capillary hemangiomas (HP:0005306)1.89654504
85Increased hepatocellular lipid droplets (HP:0006565)1.89279470
86Small hand (HP:0200055)1.88816717
87Vaginal fistula (HP:0004320)1.88160112
88Pancreatic cysts (HP:0001737)1.86615406
89Abdominal situs inversus (HP:0003363)1.86519566
90Abnormality of abdominal situs (HP:0011620)1.86519566
91Increased number of teeth (HP:0011069)1.86314362
92Lymphoma (HP:0002665)1.86158978
93Oligodactyly (hands) (HP:0001180)1.86111321
94Abnormal lung lobation (HP:0002101)1.85245523
95Abnormality of the renal collecting system (HP:0004742)1.85036069
96Long eyelashes (HP:0000527)1.84630491
97Deep philtrum (HP:0002002)1.83512941
98IgA deficiency (HP:0002720)1.83042269
99High pitched voice (HP:0001620)1.81816351
100Aplasia/Hypoplasia of the earlobes (HP:0009906)1.81452739
101Pustule (HP:0200039)1.81065532
102Lipid accumulation in hepatocytes (HP:0006561)1.80840909
103Choanal atresia (HP:0000453)1.80562545
104Neoplasm of the colon (HP:0100273)1.79562174
105Embryonal neoplasm (HP:0002898)1.79424594
10611 pairs of ribs (HP:0000878)1.79149941
107Oral leukoplakia (HP:0002745)1.79126777
108Astigmatism (HP:0000483)1.79061806
109Orthostatic hypotension (HP:0001278)1.78729400
110Molar tooth sign on MRI (HP:0002419)1.78521297
111Abnormality of midbrain morphology (HP:0002418)1.78521297
112Missing ribs (HP:0000921)1.78140686
113Amaurosis fugax (HP:0100576)1.78131754
114Homocystinuria (HP:0002156)1.76230488
115Abnormality of homocysteine metabolism (HP:0010919)1.76230488
116Shawl scrotum (HP:0000049)1.75130608
117Septo-optic dysplasia (HP:0100842)1.73376685
118Neoplasm of the pancreas (HP:0002894)1.70442273
119Broad thumb (HP:0011304)1.69324112
120Preaxial hand polydactyly (HP:0001177)1.69103305
121Acute necrotizing encephalopathy (HP:0006965)1.68959944
122Aplasia/Hypoplasia of the sternum (HP:0006714)1.68866162
123True hermaphroditism (HP:0010459)1.67786913
124Triphalangeal thumb (HP:0001199)1.67641732
125Abnormality of the anterior horn cell (HP:0006802)1.67197094
126Degeneration of anterior horn cells (HP:0002398)1.67197094
127Duplication of thumb phalanx (HP:0009942)1.66898635
128Broad alveolar ridges (HP:0000187)1.66591057
129Increased CSF lactate (HP:0002490)1.66273127
130Acute encephalopathy (HP:0006846)1.64876126
131Pallor (HP:0000980)1.64670088
132Neoplasm of the adrenal cortex (HP:0100641)1.64273639
133Hypoplastic pelvis (HP:0008839)1.63429765
134Oligohydramnios (HP:0001562)1.62152710
135Morphological abnormality of the inner ear (HP:0011390)1.61148526
136Pancreatic islet-cell hyperplasia (HP:0004510)1.60949216
137Abnormal number of erythroid precursors (HP:0012131)1.60069442
138Nephronophthisis (HP:0000090)1.59233997
139Aganglionic megacolon (HP:0002251)1.58119977
140Abnormality of cells of the erythroid lineage (HP:0012130)1.57605806
141Macrocytic anemia (HP:0001972)1.56366639
142Pancytopenia (HP:0001876)1.52678696
143Holoprosencephaly (HP:0001360)1.52157174
144Methylmalonic acidemia (HP:0002912)1.51458047
145Gastrointestinal atresia (HP:0002589)1.50484375
146Dandy-Walker malformation (HP:0001305)1.50441478
147Absent septum pellucidum (HP:0001331)1.49599109
148High anterior hairline (HP:0009890)1.48874812

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.35639275
2WEE13.27316786
3CDK123.05473156
4NEK22.95562446
5ICK2.57371775
6BUB12.28881545
7TRIM282.27378300
8CDK72.27146095
9SRPK12.26620321
10TTK2.25652062
11ATR2.23676463
12PLK12.13224402
13NUAK12.13223293
14CHEK22.11248251
15MAP3K62.09785817
16BMPR1B1.98259018
17PLK41.97636895
18TAF11.90986337
19BRSK21.84265317
20VRK21.81607255
21AURKB1.79305792
22PBK1.77325454
23CDK61.76128819
24MKNK11.71601586
25NEK11.70339279
26PIM11.69362766
27DDR21.63889996
28TNIK1.61257545
29ACVR1B1.61228432
30TLK11.59419876
31CDK41.59092923
32WNK31.56930243
33MAP3K101.55237666
34CHEK11.53739725
35BRD41.51864462
36FRK1.49153905
37STK41.47286530
38RPS6KB21.40153319
39PLK31.39559382
40EIF2AK11.37985822
41DYRK31.37057956
42ATM1.35627856
43MKNK21.34866822
44VRK11.34267226
45YES11.29582579
46MATK1.28807651
47PNCK1.24747795
48CDK21.18025902
49STK101.14806717
50ZAK1.13900266
51TSSK61.12059714
52DAPK11.07972800
53EIF2AK21.05341145
54MAP3K81.03893573
55MAP3K111.03489771
56BRSK11.02525707
57MST41.02031059
58EEF2K1.01495430
59MAP4K20.99232288
60PIM20.99094125
61PASK0.98957407
62AURKA0.93651730
63FGR0.93129009
64MAPK150.92929654
65PLK20.92387673
66CDK10.91378775
67MAP3K40.90980697
68SCYL20.90175758
69STK160.85500431
70STK30.85175086
71MTOR0.85135374
72DYRK1B0.83830432
73CSK0.83715243
74MAP4K10.80906613
75TYRO30.79921600
76TRPM70.78925253
77MELK0.78790239
78RPS6KL10.77981533
79RPS6KC10.77981533
80UHMK10.76715041
81RPS6KA40.74085982
82AKT30.69237041
83BMX0.67618918
84CSNK2A10.66774047
85RPS6KA60.66161809
86CCNB10.65875232
87CSNK2A20.64539120
88NLK0.64461315
89TGFBR10.63739597
90PDGFRA0.63272407
91LATS10.62753854
92MAPK130.61277817
93STK38L0.61182582
94MAPK110.60995899
95MAPK140.60736921
96ALK0.59698189
97CSNK1G10.59611922
98DYRK20.59535631
99NME10.59418026
100ERBB30.58884345
101FLT30.58331509
102PRKDC0.56670945
103PDK20.54061684
104BCR0.53899647
105EIF2AK30.52427111
106RPS6KB10.51764217
107GRK10.51462688
108CDK80.51419817
109TESK20.50769622
110CDK30.49240158
111CDK90.48546605
112PRKD20.47527053
113WNK40.47419092
114PAK40.46970038
115CLK10.46674443
116FGFR10.45842239
117TEC0.44951364
118NME20.43666829
119MAPK10.43266375
120CAMK1G0.42823713
121RPS6KA50.42628095
122OXSR10.41902307
123AKT10.41476469
124STK390.40592364
125CSNK1G20.40108785
126RPS6KA10.40002417
127CSNK1D0.39759529
128TAOK20.38766745
129GSK3B0.38249720
130INSRR0.38207513
131EPHA20.37250741
132CSNK1G30.36548656
133CSNK1A1L0.36039208
134MARK30.35416734
135CASK0.35303325
136LYN0.34824006
137BRAF0.34206532
138RAF10.32929806
139CSNK1E0.32501685
140CAMK1D0.30450353

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.41979632
2Mismatch repair_Homo sapiens_hsa034305.16256151
3Base excision repair_Homo sapiens_hsa034103.78821837
4Homologous recombination_Homo sapiens_hsa034403.37145812
5Cell cycle_Homo sapiens_hsa041103.18137675
6Fanconi anemia pathway_Homo sapiens_hsa034603.09027526
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.08004079
8Spliceosome_Homo sapiens_hsa030403.05458054
9RNA transport_Homo sapiens_hsa030132.90596004
10Nucleotide excision repair_Homo sapiens_hsa034202.90012065
11Non-homologous end-joining_Homo sapiens_hsa034502.49890338
12One carbon pool by folate_Homo sapiens_hsa006702.24277959
13mRNA surveillance pathway_Homo sapiens_hsa030152.19465354
14p53 signaling pathway_Homo sapiens_hsa041151.91031458
15RNA degradation_Homo sapiens_hsa030181.83439669
16Protein export_Homo sapiens_hsa030601.79942755
17RNA polymerase_Homo sapiens_hsa030201.76433932
18Systemic lupus erythematosus_Homo sapiens_hsa053221.70099789
19Ribosome_Homo sapiens_hsa030101.66758237
20Pyrimidine metabolism_Homo sapiens_hsa002401.64775164
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.59222739
22Basal transcription factors_Homo sapiens_hsa030221.49130338
23Propanoate metabolism_Homo sapiens_hsa006401.31064970
24Viral carcinogenesis_Homo sapiens_hsa052031.27059215
25Transcriptional misregulation in cancer_Homo sapiens_hsa052021.23144576
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22253440
27MicroRNAs in cancer_Homo sapiens_hsa052061.17293712
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.17163510
29Proteasome_Homo sapiens_hsa030501.13673184
30Oxidative phosphorylation_Homo sapiens_hsa001901.13626199
31Oocyte meiosis_Homo sapiens_hsa041141.12622809
32Herpes simplex infection_Homo sapiens_hsa051681.10551171
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10188824
34Parkinsons disease_Homo sapiens_hsa050121.09229630
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07448439
36Huntingtons disease_Homo sapiens_hsa050161.07161762
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.06770981
38Epstein-Barr virus infection_Homo sapiens_hsa051691.02045466
39Small cell lung cancer_Homo sapiens_hsa052220.95355403
40Lysine degradation_Homo sapiens_hsa003100.95297860
41Primary immunodeficiency_Homo sapiens_hsa053400.93819741
42HTLV-I infection_Homo sapiens_hsa051660.91789562
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.90518275
44Notch signaling pathway_Homo sapiens_hsa043300.89251909
45Steroid biosynthesis_Homo sapiens_hsa001000.88891446
46TGF-beta signaling pathway_Homo sapiens_hsa043500.87183228
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.87171277
48Pyruvate metabolism_Homo sapiens_hsa006200.85210815
49Colorectal cancer_Homo sapiens_hsa052100.81599669
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.80324661
51Fatty acid biosynthesis_Homo sapiens_hsa000610.79249667
52mTOR signaling pathway_Homo sapiens_hsa041500.79039733
53Hippo signaling pathway_Homo sapiens_hsa043900.78762897
54Adherens junction_Homo sapiens_hsa045200.78758022
55Chronic myeloid leukemia_Homo sapiens_hsa052200.76858700
56Purine metabolism_Homo sapiens_hsa002300.71580643
57Antigen processing and presentation_Homo sapiens_hsa046120.71151110
58Thyroid cancer_Homo sapiens_hsa052160.70269483
59Basal cell carcinoma_Homo sapiens_hsa052170.69300849
60Alcoholism_Homo sapiens_hsa050340.68020676
61Hepatitis B_Homo sapiens_hsa051610.67772807
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.67704504
63Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.67535730
64Hedgehog signaling pathway_Homo sapiens_hsa043400.66809212
65Phototransduction_Homo sapiens_hsa047440.66808132
66Butanoate metabolism_Homo sapiens_hsa006500.63150833
67Viral myocarditis_Homo sapiens_hsa054160.59047064
68Nitrogen metabolism_Homo sapiens_hsa009100.58164059
69Bladder cancer_Homo sapiens_hsa052190.57714928
70Measles_Homo sapiens_hsa051620.57159314
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.56591740
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.55594132
73Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55141470
74Legionellosis_Homo sapiens_hsa051340.54523984
75Wnt signaling pathway_Homo sapiens_hsa043100.51916280
76Shigellosis_Homo sapiens_hsa051310.51159582
77Prostate cancer_Homo sapiens_hsa052150.49758211
78Alzheimers disease_Homo sapiens_hsa050100.49191219
79Pancreatic cancer_Homo sapiens_hsa052120.48657934
80Biosynthesis of amino acids_Homo sapiens_hsa012300.48317604
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48192442
82NF-kappa B signaling pathway_Homo sapiens_hsa040640.47850408
83Metabolic pathways_Homo sapiens_hsa011000.46194763
84Apoptosis_Homo sapiens_hsa042100.44533508
85Non-small cell lung cancer_Homo sapiens_hsa052230.43314724
86Pathways in cancer_Homo sapiens_hsa052000.42283514
87Olfactory transduction_Homo sapiens_hsa047400.42231036
88Acute myeloid leukemia_Homo sapiens_hsa052210.42157854
89Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42098453
90Selenocompound metabolism_Homo sapiens_hsa004500.41970918
91Fatty acid elongation_Homo sapiens_hsa000620.41487641
92Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.41006259
93Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40648808
94Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.40497463
952-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.39106193
96B cell receptor signaling pathway_Homo sapiens_hsa046620.36378069
97Hematopoietic cell lineage_Homo sapiens_hsa046400.35389316
98Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.34740058
99Folate biosynthesis_Homo sapiens_hsa007900.34367661
100Glutathione metabolism_Homo sapiens_hsa004800.33777346
101Endometrial cancer_Homo sapiens_hsa052130.33604768
102Carbon metabolism_Homo sapiens_hsa012000.33264538
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33055172
104Vitamin B6 metabolism_Homo sapiens_hsa007500.33049334
105Fatty acid metabolism_Homo sapiens_hsa012120.31363074
106Intestinal immune network for IgA production_Homo sapiens_hsa046720.30832397
107N-Glycan biosynthesis_Homo sapiens_hsa005100.30566854
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.29063117
109Nicotine addiction_Homo sapiens_hsa050330.28350610
110Proteoglycans in cancer_Homo sapiens_hsa052050.28149880
111Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28052463
112FoxO signaling pathway_Homo sapiens_hsa040680.27817259
113Regulation of actin cytoskeleton_Homo sapiens_hsa048100.27762478
114Circadian rhythm_Homo sapiens_hsa047100.27736618
115Vitamin digestion and absorption_Homo sapiens_hsa049770.27533446
116Peroxisome_Homo sapiens_hsa041460.27107488
117Thyroid hormone signaling pathway_Homo sapiens_hsa049190.26954535
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26527819
119Central carbon metabolism in cancer_Homo sapiens_hsa052300.26375863
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24086090
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.23341765
122Taste transduction_Homo sapiens_hsa047420.22909793
123PI3K-Akt signaling pathway_Homo sapiens_hsa041510.22867728
124Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.22502441
125HIF-1 signaling pathway_Homo sapiens_hsa040660.21929333
126NOD-like receptor signaling pathway_Homo sapiens_hsa046210.21899380
127Influenza A_Homo sapiens_hsa051640.21818011
128Melanoma_Homo sapiens_hsa052180.21573243
129Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21526422
130Tryptophan metabolism_Homo sapiens_hsa003800.20968568
131Pentose and glucuronate interconversions_Homo sapiens_hsa000400.20926773
132Cyanoamino acid metabolism_Homo sapiens_hsa004600.20692222
133Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.20636312
134VEGF signaling pathway_Homo sapiens_hsa043700.18959916
135Maturity onset diabetes of the young_Homo sapiens_hsa049500.18824887
136Ether lipid metabolism_Homo sapiens_hsa005650.18694246
137RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.16338176
138Caffeine metabolism_Homo sapiens_hsa002320.16123231
139Pentose phosphate pathway_Homo sapiens_hsa000300.16101286
140Tight junction_Homo sapiens_hsa045300.14509076
141Renin-angiotensin system_Homo sapiens_hsa046140.14262582
142Cysteine and methionine metabolism_Homo sapiens_hsa002700.13552013
143Drug metabolism - other enzymes_Homo sapiens_hsa009830.13486423
144Linoleic acid metabolism_Homo sapiens_hsa005910.12809002
145Cardiac muscle contraction_Homo sapiens_hsa042600.12091889
146Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.11036005
147Retinol metabolism_Homo sapiens_hsa008300.09800228

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