ASPRV1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1multicellular organismal water homeostasis (GO:0050891)9.89007860
2peptide cross-linking (GO:0018149)9.35146513
3keratinocyte differentiation (GO:0030216)9.07926268
4hemidesmosome assembly (GO:0031581)8.55145602
5water homeostasis (GO:0030104)8.18625817
6intermediate filament organization (GO:0045109)7.01179891
7epidermal cell differentiation (GO:0009913)6.96404656
8bundle of His cell to Purkinje myocyte communication (GO:0086069)6.33469652
9epidermis development (GO:0008544)6.18558257
10long-chain fatty acid biosynthetic process (GO:0042759)6.06706550
11skin morphogenesis (GO:0043589)5.86685591
12keratinocyte proliferation (GO:0043616)5.61351175
13ectoderm development (GO:0007398)4.75706150
14fatty acid elongation (GO:0030497)4.74542316
15intermediate filament cytoskeleton organization (GO:0045104)4.51562167
16linoleic acid metabolic process (GO:0043651)4.49558681
17intermediate filament-based process (GO:0045103)4.40012763
18lipoxygenase pathway (GO:0019372)4.35909256
19detection of external biotic stimulus (GO:0098581)4.35839596
20detection of bacterium (GO:0016045)4.34166118
21regulation of ruffle assembly (GO:1900027)4.28443977
22adhesion of symbiont to host cell (GO:0044650)4.28339301
23virion attachment to host cell (GO:0019062)4.28339301
24glucosamine-containing compound catabolic process (GO:1901072)3.91531820
25keratinocyte development (GO:0003334)3.91198262
26sphingosine metabolic process (GO:0006670)3.82430199
27sphingoid metabolic process (GO:0046519)3.80101505
28detection of other organism (GO:0098543)3.76282123
29surfactant homeostasis (GO:0043129)3.74124039
30detection of biotic stimulus (GO:0009595)3.73088902
31epithelial cell differentiation involved in prostate gland development (GO:0060742)3.57221695
32chemical homeostasis within a tissue (GO:0048875)3.53190153
33phosphatidylinositol acyl-chain remodeling (GO:0036149)3.46128485
34adhesion of symbiont to host (GO:0044406)3.44830146
35negative regulation of interleukin-17 production (GO:0032700)3.43642033
36diol metabolic process (GO:0034311)3.38921636
37ceramide biosynthetic process (GO:0046513)3.36745484
38regulation of transforming growth factor beta1 production (GO:0032908)3.30082407
39phosphatidylserine metabolic process (GO:0006658)3.26841431
40defense response to fungus (GO:0050832)3.25010377
41positive regulation of interleukin-8 secretion (GO:2000484)3.24247087
42regulation of cell proliferation involved in kidney development (GO:1901722)3.24189989
43gap junction assembly (GO:0016264)3.17014972
44positive regulation of glomerulus development (GO:0090193)3.07702335
45negative regulation of cell fate specification (GO:0009996)3.03312358
46negative regulation of stress fiber assembly (GO:0051497)3.02553821
47long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.01814253
48positive regulation of T cell chemotaxis (GO:0010820)2.96884862
49regulation of T cell chemotaxis (GO:0010819)2.96884862
50positive regulation of cholesterol efflux (GO:0010875)2.94399893
51epithelium development (GO:0060429)2.91010762
52atrioventricular valve morphogenesis (GO:0003181)2.90505218
53phosphatidylserine acyl-chain remodeling (GO:0036150)2.90065583
54phospholipid catabolic process (GO:0009395)2.89908235
55lateral sprouting from an epithelium (GO:0060601)2.88628821
56planar cell polarity pathway involved in neural tube closure (GO:0090179)2.88406401
57hair follicle morphogenesis (GO:0031069)2.88365638
58cell-substrate junction assembly (GO:0007044)2.87869798
59polarized epithelial cell differentiation (GO:0030859)2.86948622
60negative regulation of Ras GTPase activity (GO:0034261)2.84220829
61G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.82735340
62negative regulation of keratinocyte proliferation (GO:0010839)2.80930529
63eyelid development in camera-type eye (GO:0061029)2.79447760
64sequestering of metal ion (GO:0051238)2.72857465
65phospholipid efflux (GO:0033700)2.70971594
66positive regulation of cholesterol transport (GO:0032376)2.70965268
67positive regulation of sterol transport (GO:0032373)2.70965268
68cell wall macromolecule catabolic process (GO:0016998)2.69066897
69cell wall macromolecule metabolic process (GO:0044036)2.69066897
70regulation of natural killer cell differentiation (GO:0032823)2.66904454
71phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.66411058
72regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.66074838
73positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)2.64443640
74alditol phosphate metabolic process (GO:0052646)2.62919976
75regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.61369528
76positive regulation of monocyte chemotaxis (GO:0090026)2.59519799
77positive regulation of cellular amide metabolic process (GO:0034250)2.58866183
78phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.58517910
79positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.55266573
80regulation of phospholipase A2 activity (GO:0032429)2.53871505
81fibrinolysis (GO:0042730)2.51850236
82phosphatidylglycerol metabolic process (GO:0046471)2.50838220
83polyol transport (GO:0015791)2.50199375
84establishment of planar polarity (GO:0001736)2.48916449
85establishment of tissue polarity (GO:0007164)2.48916449
86positive regulation of epidermis development (GO:0045684)2.47784432
87positive regulation of keratinocyte differentiation (GO:0045618)2.47489141
88primary alcohol catabolic process (GO:0034310)2.46776393
89fatty-acyl-CoA metabolic process (GO:0035337)2.46745902
90defense response to Gram-negative bacterium (GO:0050829)2.46043777
91molting cycle process (GO:0022404)2.45362845
92hair cycle process (GO:0022405)2.45362845
93interferon-gamma secretion (GO:0072643)2.45235667
94ventricular cardiac muscle cell action potential (GO:0086005)2.44794147
95epithelial cell-cell adhesion (GO:0090136)2.43851373
96retinol metabolic process (GO:0042572)2.41487418
97regulation of interleukin-8 secretion (GO:2000482)2.40983694
98regulation of keratinocyte differentiation (GO:0045616)2.40744965
99negative regulation of cell fate commitment (GO:0010454)2.40299635
100long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.40140208
101one-carbon compound transport (GO:0019755)2.38063584
102regulation of natural killer cell activation (GO:0032814)2.37867346
103hormone catabolic process (GO:0042447)2.36080672
104phosphatidylcholine acyl-chain remodeling (GO:0036151)2.35613852
105negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.35486783
106response to fungus (GO:0009620)2.32494173
107negative regulation of interferon-gamma production (GO:0032689)2.31860320
108positive regulation of chemokine secretion (GO:0090197)2.31186458
109regulation of cardioblast differentiation (GO:0051890)2.28136446
110regulation of neuron projection regeneration (GO:0070570)2.27295567
111regulation of axon regeneration (GO:0048679)2.27295567
112regulation of epidermis development (GO:0045682)2.26799007
113regulation of hypersensitivity (GO:0002883)2.26122621
114regulation of interleukin-17 production (GO:0032660)2.25811943
115sphingolipid biosynthetic process (GO:0030148)2.24046446
116epithelial cell differentiation (GO:0030855)2.22954267
117regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.22569842
118* skin development (GO:0043588)2.20545680
119regulation of cellular amide metabolic process (GO:0034248)2.20485775
120unsaturated fatty acid biosynthetic process (GO:0006636)2.20292337
121positive regulation of epidermal cell differentiation (GO:0045606)2.19940279
122fatty-acyl-CoA biosynthetic process (GO:0046949)2.19649426
123negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.19611242
124peptide catabolic process (GO:0043171)2.17479469
125regulation of chemokine secretion (GO:0090196)2.17416727
126hair follicle development (GO:0001942)2.15026171
127regulation of monocyte chemotaxis (GO:0090025)2.14697847
128prostanoid biosynthetic process (GO:0046457)2.14385641
129prostaglandin biosynthetic process (GO:0001516)2.14385641
130antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.11506215
131very long-chain fatty acid metabolic process (GO:0000038)2.11325503
132negative regulation of T cell receptor signaling pathway (GO:0050860)2.09533264
133modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.09307690
134positive regulation by organism of defense response of other organism involved in symbiotic interact2.09307690
135modulation by symbiont of host immune response (GO:0052553)2.09307690
136positive regulation by symbiont of host defense response (GO:0052509)2.09307690
137modulation by symbiont of host defense response (GO:0052031)2.09307690
138modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.09307690
139keratinization (GO:0031424)18.9153168
140establishment of skin barrier (GO:0061436)16.9960336
141regulation of water loss via skin (GO:0033561)14.8319930
142desmosome organization (GO:0002934)13.5590893
143hair cycle (GO:0042633)13.1416234
144molting cycle (GO:0042303)13.1416234

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.58113003
2P63_26484246_Chip-Seq_KERATINOCYTES_Human3.43570534
3GATA1_22025678_ChIP-Seq_K562_Human2.84994381
4SOX9_24532713_ChIP-Seq_HFSC_Mouse2.47123541
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.45087352
6SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.31624716
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.04442517
8ZNF263_19887448_ChIP-Seq_K562_Human2.02050301
9ESR2_21235772_ChIP-Seq_MCF-7_Human2.01036976
10TP63_17297297_ChIP-ChIP_HaCaT_Human14.5271129
11SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.98618255
12SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.98618255
13ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.98042154
14FOXO3_23340844_ChIP-Seq_DLD1_Human1.97802063
15TRIM28_21343339_ChIP-Seq_HEK293_Human1.90059130
16PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.80884841
17CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.72999902
18RARG_19884340_ChIP-ChIP_MEFs_Mouse1.48176403
19GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.46946482
20* TP63_22573176_ChIP-Seq_HFKS_Human1.42684055
21* TP63_23658742_ChIP-Seq_EP156T_Human1.42592206
22RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37665485
23SOX2_20726797_ChIP-Seq_SW620_Human1.35544542
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.35174986
25RACK7_27058665_Chip-Seq_MCF-7_Human1.33808122
26KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.32759124
27RXR_22108803_ChIP-Seq_LS180_Human1.32571853
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.30370416
29PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.30204367
30GATA6_21074721_ChIP-Seq_CACO-2_Human1.29920417
31FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.28658262
32KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.28527414
33CJUN_26792858_Chip-Seq_BT549_Human1.28116446
34HIF1A_21447827_ChIP-Seq_MCF-7_Human1.27024687
35ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26887295
36RUNX_20019798_ChIP-Seq_JUKART_Human1.25853036
37TCF4_18268006_ChIP-ChIP_LS174T_Human1.25759887
38CTCF_20526341_ChIP-Seq_ESCs_Human1.24199568
39ATF3_27146783_Chip-Seq_COLON_Human1.23902687
40KLF5_25053715_ChIP-Seq_YYC3_Human1.23039139
41BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.22991110
42CTCF_27219007_Chip-Seq_Bcells_Human1.21609612
43ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.19775053
44FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.17117130
45* RUNX1_27514584_Chip-Seq_MCF-7_Human1.17035991
46EGR1_19032775_ChIP-ChIP_M12_Human1.16782511
47CEBPB_22108803_ChIP-Seq_LS180_Human1.15333560
48BP1_19119308_ChIP-ChIP_Hs578T_Human1.14522627
49LXR_22292898_ChIP-Seq_THP-1_Human1.13033894
50UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12051654
51* GATA3_24758297_ChIP-Seq_MCF-7_Human1.11973481
52MYB_21317192_ChIP-Seq_ERMYB_Mouse1.11900607
53STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.09286436
54DNAJC2_21179169_ChIP-ChIP_NT2_Human1.09031585
55TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08251918
56UBF1/2_26484160_Chip-Seq_HMECs_Human1.06517264
57SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.06384197
58P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.06356638
59TP53_18474530_ChIP-ChIP_U2OS_Human1.03281590
60NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.01617809
61Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.01117153
62SUZ12_27294783_Chip-Seq_ESCs_Mouse0.99752530
63TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.99460412
64SA1_27219007_Chip-Seq_ERYTHROID_Human0.99373022
65* BCOR_27268052_Chip-Seq_Bcells_Human0.99347718
66GATA4_25053715_ChIP-Seq_YYC3_Human0.97920232
67RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.97407080
68JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96506943
69VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.95384868
70BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94207285
71JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94131856
72FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.93897598
73TP53_20018659_ChIP-ChIP_R1E_Mouse0.93831328
74SCL_19346495_ChIP-Seq_HPC-7_Human0.93608025
75SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.92429752
76VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.91849628
77IRF8_27001747_Chip-Seq_BMDM_Mouse0.91391908
78ERG_20517297_ChIP-Seq_VCAP_Human0.90874831
79TAF2_19829295_ChIP-Seq_ESCs_Human0.89176837
80* STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.89041839
81* E2F1_20622854_ChIP-Seq_HELA_Human0.88570441
82AHR_22903824_ChIP-Seq_MCF-7_Human0.87541528
83AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.87375214
84VDR_24787735_ChIP-Seq_THP-1_Human0.86227369
85STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.85742066
86NANOG_20526341_ChIP-Seq_ESCs_Human0.84718818
87CSB_26484114_Chip-Seq_FIBROBLAST_Human0.84709551
88CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.82717120
89GATA6_25053715_ChIP-Seq_YYC3_Human0.81559360
90* GATA2_19941826_ChIP-Seq_K562_Human0.81548789
91GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.81355738
92GATA1_19941826_ChIP-Seq_K562_Human0.80814531
93CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.80683831
94P68_20966046_ChIP-Seq_HELA_Human0.80089676
95AR_21572438_ChIP-Seq_LNCaP_Human0.79853658
96VDR_22108803_ChIP-Seq_LS180_Human0.79454724
97CLOCK_20551151_ChIP-Seq_293T_Human0.79405536
98TP53_16413492_ChIP-PET_HCT116_Human0.79223762
99IRF8_22096565_ChIP-ChIP_GC-B_Human0.78049781
100ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.77978285
101* YY1_22570637_ChIP-Seq_MALME-3M_Human0.77834545
102NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.77699975
103P53_22127205_ChIP-Seq_FIBROBLAST_Human0.77220615
104KDM2B_26808549_Chip-Seq_K562_Human0.76533547
105CDX2_19796622_ChIP-Seq_MESCs_Mouse0.76405787
106BCAT_22108803_ChIP-Seq_LS180_Human0.75930138
107ESR1_20079471_ChIP-ChIP_T-47D_Human0.75858450
108RBPJ_21746931_ChIP-Seq_IB4_Human0.75772083
109* BCL6_27268052_Chip-Seq_Bcells_Human0.74234260
110ELK3_25401928_ChIP-Seq_HUVEC_Human0.73765448
111KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.73303225
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.73146022
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.73146022
114KDM2B_26808549_Chip-Seq_SUP-B15_Human0.72829742
115GATA2_21666600_ChIP-Seq_HMVEC_Human0.72715506
116P300_27058665_Chip-Seq_ZR-75-30cells_Human0.72563565
117SOX2_27498859_Chip-Seq_STOMACH_Mouse0.70808918
118OCT1_27270436_Chip-Seq_PROSTATE_Human0.70738763
119HNFA_21074721_ChIP-Seq_CACO-2_Human0.70576122
120RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.70550630
121ARNT_22903824_ChIP-Seq_MCF-7_Human0.70534895
122JARID2_20075857_ChIP-Seq_MESCs_Mouse0.69942479
123JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.69377993
124EZH2_27294783_Chip-Seq_ESCs_Mouse0.68826379
125ERG_21242973_ChIP-ChIP_JURKAT_Human0.68791834
126P53_21459846_ChIP-Seq_SAOS-2_Human0.68372687
127PPAR_26484153_Chip-Seq_NCI-H1993_Human0.67718934
128SMC4_20622854_ChIP-Seq_HELA_Human0.66929917
129SA1_27219007_Chip-Seq_Bcells_Human0.66670360
130FOXH1_21741376_ChIP-Seq_ESCs_Human0.66552627
131FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.66294107

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier8.47534014
2MP0005275_abnormal_skin_tensile6.82492151
3MP0005501_abnormal_skin_physiology5.22226265
4MP0010234_abnormal_vibrissa_follicle5.01738328
5MP0000579_abnormal_nail_morphology4.89307968
6MP0003941_abnormal_skin_development4.14944240
7MP0001216_abnormal_epidermal_layer3.46017777
8MP0002254_reproductive_system_inflammat3.37959495
9MP0002060_abnormal_skin_morphology3.33120286
10MP0004947_skin_inflammation3.22271602
11MP0010771_integument_phenotype3.13490774
12MP0004381_abnormal_hair_follicle3.09022625
13MP0000383_abnormal_hair_follicle3.08419017
14MP0010678_abnormal_skin_adnexa2.98351754
15MP0002098_abnormal_vibrissa_morphology2.92616171
16MP0000647_abnormal_sebaceous_gland2.91866238
17MP0005451_abnormal_body_composition2.83146700
18MP0003453_abnormal_keratinocyte_physiol2.80205506
19MP0003705_abnormal_hypodermis_morpholog2.74904998
20MP0000467_abnormal_esophagus_morphology2.61402403
21MP0000377_abnormal_hair_follicle2.40494798
22MP0003878_abnormal_ear_physiology2.34985765
23MP0005377_hearing/vestibular/ear_phenot2.34985765
24MP0000427_abnormal_hair_cycle2.25532327
25MP0000015_abnormal_ear_pigmentation2.12889888
26MP0000762_abnormal_tongue_morphology1.91055759
27MP0005174_abnormal_tail_pigmentation1.82358954
28MP0004885_abnormal_endolymph1.81564021
29MP0003191_abnormal_cellular_cholesterol1.79194061
30* MP0009931_abnormal_skin_appearance1.75545524
31MP0001243_abnormal_dermal_layer1.70625304
32MP0004185_abnormal_adipocyte_glucose1.70209164
33MP0005075_abnormal_melanosome_morpholog1.66200537
34MP0001191_abnormal_skin_condition1.63546535
35MP0003566_abnormal_cell_adhesion1.55204449
36MP0003303_peritoneal_inflammation1.47054767
37MP0002234_abnormal_pharynx_morphology1.43233447
38* MP0000367_abnormal_coat/_hair1.38543379
39MP0000566_synostosis1.21154732
40MP0001851_eye_inflammation1.15192513
41MP0003011_delayed_dark_adaptation1.12367294
42MP0001346_abnormal_lacrimal_gland1.12053698
43MP0004782_abnormal_surfactant_physiolog1.11855526
44MP0005171_absent_coat_pigmentation1.09962865
45MP0000465_gastrointestinal_hemorrhage0.99052895
46MP0001188_hyperpigmentation0.95525349
47MP0002095_abnormal_skin_pigmentation0.93339406
48MP0005409_darkened_coat_color0.85851331
49MP0002877_abnormal_melanocyte_morpholog0.84213626
50MP0000372_irregular_coat_pigmentation0.84184433
51MP0005023_abnormal_wound_healing0.79086434
52MP0000569_abnormal_digit_pigmentation0.78595998
53MP0003724_increased_susceptibility_to0.77883849
54MP0001340_abnormal_eyelid_morphology0.71812449
55MP0009053_abnormal_anal_canal0.70334837
56MP0002009_preneoplasia0.69888825
57MP0001784_abnormal_fluid_regulation0.66885351
58MP0006082_CNS_inflammation0.66549490
59MP0003950_abnormal_plasma_membrane0.66484327
60MP0002177_abnormal_outer_ear0.65667045
61MP0001849_ear_inflammation0.65568770
62MP0010352_gastrointestinal_tract_polyps0.63285108
63MP0009333_abnormal_splenocyte_physiolog0.63001988
64MP0008438_abnormal_cutaneous_collagen0.61885324
65MP0009379_abnormal_foot_pigmentation0.59551195
66MP0003300_gastrointestinal_ulcer0.57278626
67MP0005076_abnormal_cell_differentiation0.54336536
68MP0003436_decreased_susceptibility_to0.50383274
69MP0010030_abnormal_orbit_morphology0.49097702
70MP0005666_abnormal_adipose_tissue0.48181165
71MP0008961_abnormal_basal_metabolism0.46528893
72MP0002166_altered_tumor_susceptibility0.44210413
73MP0005025_abnormal_response_to0.42249273
74MP0000627_abnormal_mammary_gland0.41916026
75MP0002006_tumorigenesis0.41490912
76MP0002282_abnormal_trachea_morphology0.40942992
77MP0003755_abnormal_palate_morphology0.40746892
78MP0005408_hypopigmentation0.38324418
79MP0001186_pigmentation_phenotype0.38038639
80MP0005375_adipose_tissue_phenotype0.36773706
81MP0005387_immune_system_phenotype0.34930896
82MP0001790_abnormal_immune_system0.34930896
83MP0001800_abnormal_humoral_immune0.34791490
84MP0003763_abnormal_thymus_physiology0.34701980
85MP0006054_spinal_hemorrhage0.34570592
86MP0000470_abnormal_stomach_morphology0.33463575
87MP0000371_diluted_coat_color0.33432690
88MP0002111_abnormal_tail_morphology0.33338168
89MP0005671_abnormal_response_to0.33284987
90MP0003136_yellow_coat_color0.32558936
91MP0001984_abnormal_olfaction0.31374801
92MP0004264_abnormal_extraembryonic_tissu0.30730237
93MP0004019_abnormal_vitamin_homeostasis0.30391956
94MP0008004_abnormal_stomach_pH0.29333477
95MP0000858_altered_metastatic_potential0.29134210
96MP0003828_pulmonary_edema0.27659697
97MP0005647_abnormal_sex_gland0.27047845
98MP0003329_amyloid_beta_deposits0.26073240
99MP0008260_abnormal_autophagy0.25906284
100MP0000538_abnormal_urinary_bladder0.25523170
101MP0002419_abnormal_innate_immunity0.25481476
102MP0001958_emphysema0.25336952
103MP0000751_myopathy0.24916968
104MP0003448_altered_tumor_morphology0.23765111
105MP0005248_abnormal_Harderian_gland0.23446063
106MP0004272_abnormal_basement_membrane0.23443529
107MP0003315_abnormal_perineum_morphology0.23140504
108MP0000750_abnormal_muscle_regeneration0.23129735
109MP0000749_muscle_degeneration0.22942627
110MP0002971_abnormal_brown_adipose0.22184227
111MP0009384_cardiac_valve_regurgitation0.22059369
112MP0002138_abnormal_hepatobiliary_system0.21665679
113MP0000685_abnormal_immune_system0.21314088
114MP0001533_abnormal_skeleton_physiology0.20975790
115MP0005000_abnormal_immune_tolerance0.20923761
116MP0005257_abnormal_intraocular_pressure0.20874993
117MP0002148_abnormal_hypersensitivity_rea0.20491286
118MP0003075_altered_response_to0.19853694
119MP0001177_atelectasis0.19722098
120MP0009780_abnormal_chondrocyte_physiolo0.18688902
121MP0002420_abnormal_adaptive_immunity0.18424542
122MP0003638_abnormal_response/metabolism_0.18410836
123MP0005388_respiratory_system_phenotype0.18398370
124MP0002133_abnormal_respiratory_system0.18398370
125MP0002452_abnormal_antigen_presenting0.18372725
126MP0002249_abnormal_larynx_morphology0.18338181
127MP0005193_abnormal_anterior_eye0.18077927
128MP0002075_abnormal_coat/hair_pigmentati0.18075517
129MP0001819_abnormal_immune_cell0.17869054
130MP0002090_abnormal_vision0.17851614
131MP0000733_abnormal_muscle_development0.17159553
132MP0010155_abnormal_intestine_physiology0.17088146
133MP0005508_abnormal_skeleton_morphology0.16629856
134MP0000747_muscle_weakness0.16026740
135MP0001873_stomach_inflammation0.15803428
136MP0000432_abnormal_head_morphology0.15669284
137MP0005367_renal/urinary_system_phenotyp0.15215096
138MP0000516_abnormal_urinary_system0.15215096

Predicted human phenotypes

RankGene SetZ-score
1Increased IgE level (HP:0003212)8.73148615
2Abnormality of nail color (HP:0100643)8.42304030
3Hypotrichosis (HP:0001006)8.07800731
4Palmoplantar hyperkeratosis (HP:0000972)7.03969566
5Plantar hyperkeratosis (HP:0007556)6.99560556
6Palmar hyperkeratosis (HP:0010765)6.63444535
7Woolly hair (HP:0002224)6.58325712
8Congenital ichthyosiform erythroderma (HP:0007431)6.55192916
9Onycholysis (HP:0001806)6.13961800
10Thick nail (HP:0001805)5.94293288
11Conjunctival hamartoma (HP:0100780)5.77167654
12Erythroderma (HP:0001019)5.75962080
13Erythema (HP:0010783)5.71253371
14Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.60207296
15Right ventricular cardiomyopathy (HP:0011663)5.53789511
16Fragile nails (HP:0001808)5.30955389
17Pili torti (HP:0003777)5.11870281
18Milia (HP:0001056)4.95449730
19Gangrene (HP:0100758)4.72915253
20Oral leukoplakia (HP:0002745)4.39768677
21Nail dystrophy (HP:0008404)4.36408323
22Abnormal blistering of the skin (HP:0008066)4.35024022
23Ectropion (HP:0000656)4.18713113
24Alopecia of scalp (HP:0002293)4.06682524
25Corneal erosion (HP:0200020)4.01507733
26Lip pit (HP:0100267)3.91941244
27Parakeratosis (HP:0001036)3.73051749
28Palmoplantar keratoderma (HP:0000982)3.66838377
29Hamartoma of the eye (HP:0010568)3.65724176
30Eczematoid dermatitis (HP:0000976)3.57518547
31Absent eyelashes (HP:0000561)3.51237677
32Hypohidrosis (HP:0000966)3.50683123
33Hyporeflexia of lower limbs (HP:0002600)3.39283106
34Follicular hyperkeratosis (HP:0007502)3.33303465
35Pruritus (HP:0000989)3.26344131
36Abnormal hair laboratory examination (HP:0003328)3.25605900
37Curly hair (HP:0002212)3.10164710
38Absent hair (HP:0002298)3.06325434
39Atrophic scars (HP:0001075)2.87268770
40Sparse eyelashes (HP:0000653)2.86490722
41Ridged nail (HP:0001807)2.86461879
42Ventricular tachycardia (HP:0004756)2.79443933
43Distal lower limb muscle weakness (HP:0009053)2.69252232
44Brittle hair (HP:0002299)2.69203611
45Hypergammaglobulinemia (HP:0010702)2.68071370
46Advanced eruption of teeth (HP:0006288)2.67441865
47Lack of skin elasticity (HP:0100679)2.66299681
48Type 1 muscle fiber predominance (HP:0003803)2.63713577
49Natal tooth (HP:0000695)2.60322122
50Dry hair (HP:0011359)2.57648154
51Increased connective tissue (HP:0009025)2.53910218
52Duplicated collecting system (HP:0000081)2.53541795
53Abnormality of the neuromuscular junction (HP:0003398)2.52335372
54Fatigable weakness (HP:0003473)2.52335372
55Round ear (HP:0100830)2.51276292
56Pustule (HP:0200039)2.44112234
57Distal arthrogryposis (HP:0005684)2.41706797
58Muscle fiber inclusion bodies (HP:0100299)2.33909590
59Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.32556444
60Acanthosis nigricans (HP:0000956)2.30430983
61Autoamputation (HP:0001218)2.30392715
62Nemaline bodies (HP:0003798)2.25316684
63Furrowed tongue (HP:0000221)2.24392577
64Areflexia of lower limbs (HP:0002522)2.21492382
65Abnormality of the renal collecting system (HP:0004742)2.17202268
66Abnormality of hair growth rate (HP:0011363)2.14133824
67Slow-growing hair (HP:0002217)2.14133824
68Hyperhidrosis (HP:0000975)2.10337011
69Myopathic facies (HP:0002058)2.07082596
70Sparse scalp hair (HP:0002209)2.06906935
71Blepharitis (HP:0000498)2.03104360
72Dehydration (HP:0001944)2.02601272
73Ulnar deviation of the wrist (HP:0003049)2.00994433
74Skin ulcer (HP:0200042)1.98661750
75Fine hair (HP:0002213)1.96153790
76Corneal dystrophy (HP:0001131)1.95995424
77Keratoconjunctivitis sicca (HP:0001097)1.94028167
78Abnormality of the salivary glands (HP:0010286)1.90736864
79Malignant hyperthermia (HP:0002047)1.89456234
80Xerostomia (HP:0000217)1.88813648
81Anonychia (HP:0001798)1.88734926
82Recurrent bacterial skin infections (HP:0005406)1.88450815
83Laryngomalacia (HP:0001601)1.85735701
84Split foot (HP:0001839)1.83176073
85Fragile skin (HP:0001030)1.82668540
86Exercise-induced myalgia (HP:0003738)1.81203468
87Dry skin (HP:0000958)1.79646768
88Sepsis (HP:0100806)1.78715809
89Multifactorial inheritance (HP:0001426)1.76062165
90Keratoconjunctivitis (HP:0001096)1.75497671
91Popliteal pterygium (HP:0009756)1.75342391
92Calcaneovalgus deformity (HP:0001848)1.73657148
93Paralysis (HP:0003470)1.71970700
94Selective tooth agenesis (HP:0001592)1.71871660
95Amniotic constriction ring (HP:0009775)1.71769663
96Abnormality of placental membranes (HP:0011409)1.71769663
97Abnormality of the gastric mucosa (HP:0004295)1.70079688
98Conical tooth (HP:0000698)1.70020962
99Recurrent skin infections (HP:0001581)1.69457668
100Hamartoma (HP:0010566)1.69434426
101Abnormality of the labia majora (HP:0012881)1.69352269
102Aplasia cutis congenita (HP:0001057)1.69090520
103Muscle fiber splitting (HP:0003555)1.68102411
104Verrucae (HP:0200043)1.67414764
105Papilloma (HP:0012740)1.67414764
106Abnormality of permanent molar morphology (HP:0011071)1.67122617
107Abnormality of the dental root (HP:0006486)1.67122617
108Taurodontia (HP:0000679)1.67122617
109Anhidrosis (HP:0000970)1.66350074
110Ventricular fibrillation (HP:0001663)1.65516171
111Congenital, generalized hypertrichosis (HP:0004540)1.65014285
112Abnormality of the axillary hair (HP:0100134)1.63743968
113Abnormality of secondary sexual hair (HP:0009888)1.63743968
114Neck muscle weakness (HP:0000467)1.62665966
115Achilles tendon contracture (HP:0001771)1.61537817
116Melanocytic nevus (HP:0000995)1.59404618
117Absent phalangeal crease (HP:0006109)1.58918595
118Nasolacrimal duct obstruction (HP:0000579)1.57288999
119Abnormality of the fingernails (HP:0001231)1.57259426
120Abnormality of molar (HP:0011077)1.56147553
121Abnormality of molar morphology (HP:0011070)1.56147553
122Sudden death (HP:0001699)1.55640857
123Urticaria (HP:0001025)1.52947647
124Recurrent corneal erosions (HP:0000495)1.51257365
125Deformed tarsal bones (HP:0008119)1.51231674
126Abnormality of the dental pulp (HP:0006479)1.48292183
127Amelogenesis imperfecta (HP:0000705)1.47991408
128Distal lower limb amyotrophy (HP:0008944)1.47941383
129Difficulty running (HP:0009046)1.46910222
130Hypoplastic labia majora (HP:0000059)1.46028225
131Carious teeth (HP:0000670)1.40356255
132Septate vagina (HP:0001153)1.39878023
133Ureteral duplication (HP:0000073)1.39068441
134Aplasia of the phalanges of the hand (HP:0009802)1.34298672
135Aplasia involving bones of the extremities (HP:0009825)1.34298672

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MKNK25.36327256
2MAPKAPK34.86490527
3MST1R3.85726338
4MAP3K33.80604358
5FER3.56647077
6TGFBR13.50231904
7TTN3.09601646
8ERN12.83617695
9PIK3CG2.76604650
10MKNK12.68663108
11MAP3K22.45305840
12MST42.34463166
13JAK32.25906922
14FGFR12.23225446
15RIPK12.22602427
16RPS6KB22.01202679
17EPHA22.01052910
18TRIB31.95491883
19TAOK11.95184675
20MAP3K111.91417967
21OBSCN1.90078534
22LATS11.80079603
23EPHB11.77081138
24MAP2K31.71498241
25TRPM71.64612649
26MAP2K61.60402280
27BLK1.49007505
28EPHB21.47893523
29IRAK41.42457687
30PTK61.41333784
31FGFR41.37720808
32LRRK21.35844406
33PRPF4B1.35842955
34GRK61.34227214
35EPHA31.33046402
36MAP3K61.31415088
37SGK2231.26682913
38SGK4941.26682913
39MAP3K11.24288902
40MAP3K71.21266260
41ABL21.19358497
42FGFR21.16518729
43MAP3K141.16394571
44MET1.15556163
45STK241.15366728
46ERBB31.11718997
47FGFR31.10947442
48EEF2K1.10799018
49MAPK71.10491480
50IRAK11.10423895
51TYK21.10034445
52MAPKAPK51.09832546
53TGFBR21.08545507
54MAPKAPK21.03483201
55DYRK1B1.01723064
56STK101.01432707
57KIT1.00658953
58RPS6KA41.00502474
59MAP3K90.99127891
60BCR0.96066600
61NME10.95532133
62TIE10.92779984
63TESK10.88563455
64PIM20.86153510
65DYRK1A0.85493500
66TBK10.80792514
67PTK20.79353689
68NLK0.78026942
69FGR0.74219297
70IKBKE0.73869017
71SGK20.71501163
72ITK0.71400406
73CDK60.71110802
74MAP3K120.70725853
75PRKD20.69647189
76NTRK20.69377049
77MAP2K40.68715685
78LATS20.65556228
79BMX0.62534578
80PRKD10.60908412
81MAP4K10.59787004
82DDR20.58262140
83DMPK0.58202797
84TYRO30.56549277
85MAP2K10.56176442
86SGK30.55660542
87RPS6KB10.53376498
88PHKG20.52985171
89PHKG10.52985171
90IRAK20.51236001
91MARK30.50324217
92TNK20.50035197
93TXK0.49426231
94ZAP700.49343315
95KSR20.47615922
96HCK0.46470833
97MAP3K50.46462220
98FES0.44813106
99ILK0.43934356
100RIPK40.43206176
101STK110.42753924
102PRKCI0.42316564
103MAPK120.41644705
104WNK10.40779172
105PDGFRA0.39736896
106IKBKB0.39634845
107LIMK10.38392288
108RPS6KA10.38059412
109SIK10.37742931
110PAK30.37300967
111CSK0.37227716
112RET0.37155083
113JAK20.37109064
114JAK10.35630418
115ABL10.32896618
116MARK20.32139231
117MATK0.30588065
118PKN10.30013191
119PRKAA20.29743031
120MAPK110.29731275
121TAOK30.28914524
122SYK0.28750875
123ERBB20.27235654
124GSK3A0.27087740
125SGK10.26742982
126BRD40.25204091
127MAPK40.24729409
128ADRBK10.24489085
129TAOK20.24402263
130PRKCD0.24199976
131PKN20.23299892
132SMG10.23280743
133MAP2K20.23251553
134MAP3K100.22996061
135CHUK0.21501427
136PRKCQ0.20728929
137BTK0.20498244
138SIK30.20206713
139STK30.20032522
140GRK70.17126624

Predicted pathways (KEGG)

RankGene SetZ-score
1Linoleic acid metabolism_Homo sapiens_hsa005913.24144172
2alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.22308494
3Arachidonic acid metabolism_Homo sapiens_hsa005902.75838248
4Sphingolipid metabolism_Homo sapiens_hsa006002.67508291
5Fatty acid elongation_Homo sapiens_hsa000622.58132111
6Cyanoamino acid metabolism_Homo sapiens_hsa004602.28412796
7Histidine metabolism_Homo sapiens_hsa003402.28033978
8Phenylalanine metabolism_Homo sapiens_hsa003602.11075678
9Staphylococcus aureus infection_Homo sapiens_hsa051501.97332273
10Ether lipid metabolism_Homo sapiens_hsa005651.95612701
11VEGF signaling pathway_Homo sapiens_hsa043701.84452262
12Fat digestion and absorption_Homo sapiens_hsa049751.74381581
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.70003142
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.66167453
15Ovarian steroidogenesis_Homo sapiens_hsa049131.65923350
16Tight junction_Homo sapiens_hsa045301.45301623
17ECM-receptor interaction_Homo sapiens_hsa045121.40705321
18Adherens junction_Homo sapiens_hsa045201.40430569
19Choline metabolism in cancer_Homo sapiens_hsa052311.36115627
20Basal cell carcinoma_Homo sapiens_hsa052171.34979453
21Retinol metabolism_Homo sapiens_hsa008301.33193918
22Pertussis_Homo sapiens_hsa051331.30392675
23GnRH signaling pathway_Homo sapiens_hsa049121.28930885
24Leukocyte transendothelial migration_Homo sapiens_hsa046701.26924601
25SNARE interactions in vesicular transport_Homo sapiens_hsa041301.26358674
26Amoebiasis_Homo sapiens_hsa051461.21750952
27ABC transporters_Homo sapiens_hsa020101.21209719
28Proteoglycans in cancer_Homo sapiens_hsa052051.17736376
29Tyrosine metabolism_Homo sapiens_hsa003501.17042751
30Toxoplasmosis_Homo sapiens_hsa051451.15097143
31Bladder cancer_Homo sapiens_hsa052191.13289877
32Sphingolipid signaling pathway_Homo sapiens_hsa040711.11752402
33Axon guidance_Homo sapiens_hsa043601.05063353
34Renin secretion_Homo sapiens_hsa049241.04796875
35Phospholipase D signaling pathway_Homo sapiens_hsa040721.03433435
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.02855645
37Circadian rhythm_Homo sapiens_hsa047101.00978622
38Melanogenesis_Homo sapiens_hsa049160.98671227
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.98292559
40Leishmaniasis_Homo sapiens_hsa051400.97688565
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.97179919
42NOD-like receptor signaling pathway_Homo sapiens_hsa046210.96534604
43Acute myeloid leukemia_Homo sapiens_hsa052210.90885025
44Vascular smooth muscle contraction_Homo sapiens_hsa042700.90345724
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.89780445
46Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88410751
47Tuberculosis_Homo sapiens_hsa051520.87933065
48Hippo signaling pathway_Homo sapiens_hsa043900.87756086
49Platelet activation_Homo sapiens_hsa046110.85846167
50Salivary secretion_Homo sapiens_hsa049700.85661726
51Phototransduction_Homo sapiens_hsa047440.84717917
52Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.84117424
53Hepatitis C_Homo sapiens_hsa051600.83710010
54Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.83430849
55AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81930296
56Caffeine metabolism_Homo sapiens_hsa002320.81238699
57Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.80892854
58Pancreatic secretion_Homo sapiens_hsa049720.80635746
59Ras signaling pathway_Homo sapiens_hsa040140.80488258
60Malaria_Homo sapiens_hsa051440.79757738
61Insulin resistance_Homo sapiens_hsa049310.78537953
62TNF signaling pathway_Homo sapiens_hsa046680.77963014
63Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77387056
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.76675955
65Dorso-ventral axis formation_Homo sapiens_hsa043200.75968150
66Hedgehog signaling pathway_Homo sapiens_hsa043400.75712806
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.75114474
68Osteoclast differentiation_Homo sapiens_hsa043800.74036268
69Focal adhesion_Homo sapiens_hsa045100.72218469
70MicroRNAs in cancer_Homo sapiens_hsa052060.71148510
71p53 signaling pathway_Homo sapiens_hsa041150.71109799
72Long-term depression_Homo sapiens_hsa047300.69946960
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.67209822
74Gastric acid secretion_Homo sapiens_hsa049710.67192965
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.66328531
76Glioma_Homo sapiens_hsa052140.65829347
77Salmonella infection_Homo sapiens_hsa051320.65805876
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.65647073
79Chemical carcinogenesis_Homo sapiens_hsa052040.64991698
80Glycerolipid metabolism_Homo sapiens_hsa005610.63440033
81Serotonergic synapse_Homo sapiens_hsa047260.63437642
82Rap1 signaling pathway_Homo sapiens_hsa040150.62839756
83Influenza A_Homo sapiens_hsa051640.62580228
84Glycerophospholipid metabolism_Homo sapiens_hsa005640.60845377
85Protein digestion and absorption_Homo sapiens_hsa049740.60843774
86Inositol phosphate metabolism_Homo sapiens_hsa005620.60517600
87Olfactory transduction_Homo sapiens_hsa047400.59585706
88Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59530273
89Legionellosis_Homo sapiens_hsa051340.58571280
90Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58325747
91Chemokine signaling pathway_Homo sapiens_hsa040620.56633415
92Fatty acid biosynthesis_Homo sapiens_hsa000610.56419967
93Vitamin digestion and absorption_Homo sapiens_hsa049770.55530375
94Phagosome_Homo sapiens_hsa041450.55390975
95Small cell lung cancer_Homo sapiens_hsa052220.55292241
96Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54784701
97Estrogen signaling pathway_Homo sapiens_hsa049150.54784321
98Oxytocin signaling pathway_Homo sapiens_hsa049210.54542007
99ErbB signaling pathway_Homo sapiens_hsa040120.53615078
100beta-Alanine metabolism_Homo sapiens_hsa004100.53473217
101Steroid biosynthesis_Homo sapiens_hsa001000.53266779
102Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52765182
103Aldosterone synthesis and secretion_Homo sapiens_hsa049250.52496327
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.51219414
105Apoptosis_Homo sapiens_hsa042100.49618546
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.49216501
107Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48805685
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48638701
109Mineral absorption_Homo sapiens_hsa049780.48414261
110Graft-versus-host disease_Homo sapiens_hsa053320.48181089
111Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.48064854
112Ribosome_Homo sapiens_hsa030100.48056414
113MAPK signaling pathway_Homo sapiens_hsa040100.48031150
114Glutamatergic synapse_Homo sapiens_hsa047240.47259762
115Long-term potentiation_Homo sapiens_hsa047200.46987726
116Endocytosis_Homo sapiens_hsa041440.46129994
117Notch signaling pathway_Homo sapiens_hsa043300.44197738
118Insulin signaling pathway_Homo sapiens_hsa049100.43875685
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.43772044
120Pancreatic cancer_Homo sapiens_hsa052120.43353206
121Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42374244
122Autoimmune thyroid disease_Homo sapiens_hsa053200.41385528
123Allograft rejection_Homo sapiens_hsa053300.41262885
124Circadian entrainment_Homo sapiens_hsa047130.40144400
125Renal cell carcinoma_Homo sapiens_hsa052110.39369281
126B cell receptor signaling pathway_Homo sapiens_hsa046620.38958509
127PPAR signaling pathway_Homo sapiens_hsa033200.35559743
128Measles_Homo sapiens_hsa051620.34737749
129T cell receptor signaling pathway_Homo sapiens_hsa046600.33245760
130Thyroid cancer_Homo sapiens_hsa052160.32402349
131Hematopoietic cell lineage_Homo sapiens_hsa046400.31395715

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