ASB5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-mediated cell contraction (GO:0070252)9.70026602
2skeletal muscle fiber development (GO:0048741)9.56720994
3regulation of skeletal muscle contraction (GO:0014819)9.47622351
4sarcoplasmic reticulum calcium ion transport (GO:0070296)8.82422754
5muscle cell fate commitment (GO:0042693)8.80199695
6plasma membrane repair (GO:0001778)8.16575641
7myotube cell development (GO:0014904)8.11926571
8skeletal muscle tissue regeneration (GO:0043403)7.60844304
9actin filament-based movement (GO:0030048)7.43606270
10response to stimulus involved in regulation of muscle adaptation (GO:0014874)7.13262137
11skeletal muscle adaptation (GO:0043501)7.03401185
12response to inactivity (GO:0014854)6.90938595
13striated muscle atrophy (GO:0014891)6.77978676
14sarcomere organization (GO:0045214)6.43583199
15positive regulation of myotube differentiation (GO:0010831)6.23927724
16striated muscle contraction (GO:0006941)6.11646178
17myoblast fusion (GO:0007520)5.93903589
18muscle atrophy (GO:0014889)5.84073407
19positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.73287349
20muscle fiber development (GO:0048747)5.67536093
21syncytium formation by plasma membrane fusion (GO:0000768)5.54132123
22muscle contraction (GO:0006936)5.44156718
23syncytium formation (GO:0006949)5.33561943
24myotube differentiation (GO:0014902)5.32707151
25response to muscle activity (GO:0014850)5.28211912
26myofibril assembly (GO:0030239)5.18385721
27negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.11305978
28muscle cell cellular homeostasis (GO:0046716)5.05420927
29regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.01722598
30skeletal muscle tissue development (GO:0007519)5.00472330
31muscle system process (GO:0003012)4.84744856
32muscle organ development (GO:0007517)4.82275425
33striated muscle adaptation (GO:0014888)4.76596603
34muscle structure development (GO:0061061)4.72672101
35actomyosin structure organization (GO:0031032)4.71262810
36regulation of cell communication by electrical coupling (GO:0010649)4.67494496
37regulation of skeletal muscle cell differentiation (GO:2001014)4.48190870
38creatine metabolic process (GO:0006600)4.43077446
39striated muscle cell development (GO:0055002)4.42846836
40regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.40873144
41heart contraction (GO:0060047)4.31494565
42heart process (GO:0003015)4.31494565
43positive regulation of skeletal muscle tissue development (GO:0048643)4.29930287
44positive regulation of myoblast differentiation (GO:0045663)4.29222440
45neuromuscular synaptic transmission (GO:0007274)4.26653514
46multicellular organismal movement (GO:0050879)4.25752223
47musculoskeletal movement (GO:0050881)4.25752223
48glycogen catabolic process (GO:0005980)4.09886888
49regulation of syncytium formation by plasma membrane fusion (GO:0060142)4.05641962
50neuromuscular junction development (GO:0007528)4.03569660
51cardiac muscle hypertrophy (GO:0003300)4.02256079
52regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.99707771
53cardiac muscle tissue morphogenesis (GO:0055008)3.98736040
54skeletal muscle cell differentiation (GO:0035914)3.98309109
55negative regulation of potassium ion transmembrane transport (GO:1901380)3.95852320
56muscle cell development (GO:0055001)3.93842519
57carnitine shuttle (GO:0006853)3.88643645
58muscle adaptation (GO:0043500)3.84629758
59striated muscle hypertrophy (GO:0014897)3.82500790
60glucan catabolic process (GO:0009251)3.81596981
61glucan biosynthetic process (GO:0009250)3.78051439
62glycogen biosynthetic process (GO:0005978)3.78051439
63positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.76570751
64cardiac myofibril assembly (GO:0055003)3.69856304
65negative regulation of protein localization to cell surface (GO:2000009)3.67646932
66regulation of relaxation of muscle (GO:1901077)3.67101409
67NADH metabolic process (GO:0006734)3.55779662
68regulation of sarcomere organization (GO:0060297)3.55269673
69negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.53409265
70cardiac muscle contraction (GO:0060048)3.52161019
71cellular polysaccharide catabolic process (GO:0044247)3.48301074
72regulation of myoblast differentiation (GO:0045661)3.47174842
73regulation of myotube differentiation (GO:0010830)3.46300116
74regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.45251744
75positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.45159490
76pyrimidine ribonucleoside catabolic process (GO:0046133)3.43862586
77positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.42472542
78muscle hypertrophy (GO:0014896)3.37244666
79regulation of muscle system process (GO:0090257)3.36969069
80cytidine metabolic process (GO:0046087)3.34844825
81cytidine catabolic process (GO:0006216)3.34844825
82cytidine deamination (GO:0009972)3.34844825
83striated muscle tissue development (GO:0014706)3.34548601
84negative regulation of calcium ion transmembrane transport (GO:1903170)3.30877627
85negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.30877627
86positive regulation of muscle cell differentiation (GO:0051149)3.29834692
87regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.29311850
88polysaccharide catabolic process (GO:0000272)3.28236633
89regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.27572000
90muscle organ morphogenesis (GO:0048644)3.25497217
91negative regulation of cell size (GO:0045792)3.24074598
92fatty acid transmembrane transport (GO:1902001)3.23335597
93cardiac muscle cell development (GO:0055013)3.22884980
94regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.20952767
95purine nucleotide salvage (GO:0032261)3.20661076
96regulation of membrane repolarization (GO:0060306)3.17429990
97regulation of striated muscle contraction (GO:0006942)3.16911103
98negative regulation of muscle contraction (GO:0045932)3.14146498
99adult heart development (GO:0007512)3.13024359
100regulation of muscle contraction (GO:0006937)3.10758556
101regulation of acyl-CoA biosynthetic process (GO:0050812)3.10053411
102regulation of the force of heart contraction (GO:0002026)3.07113646
103glycogen metabolic process (GO:0005977)3.06580556
104cardiac cell development (GO:0055006)3.04243123
105response to activity (GO:0014823)3.03142496
106regulation of calcium ion transmembrane transport (GO:1903169)3.00941890
107regulation of calcium ion transmembrane transporter activity (GO:1901019)3.00941890
108regulation of actin filament-based movement (GO:1903115)3.00299791
109glucan metabolic process (GO:0044042)2.99837304
110cellular glucan metabolic process (GO:0006073)2.99837304
111muscle tissue development (GO:0060537)2.99667296
112regulation of p38MAPK cascade (GO:1900744)2.95943395
113muscle tissue morphogenesis (GO:0060415)2.93323629
114regulation of skeletal muscle tissue development (GO:0048641)2.91968298
115organ induction (GO:0001759)2.90585681
116carnitine transmembrane transport (GO:1902603)2.88456828
117regulation of cofactor metabolic process (GO:0051193)2.84867262
118regulation of coenzyme metabolic process (GO:0051196)2.84867262
119IMP metabolic process (GO:0046040)2.83589141
120regulation of skeletal muscle fiber development (GO:0048742)2.80794305
121muscle filament sliding (GO:0030049)11.6520062
122actin-myosin filament sliding (GO:0033275)11.6520062
123skeletal muscle contraction (GO:0003009)10.7830457

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RARG_19884340_ChIP-ChIP_MEFs_Mouse3.89030826
2ESR1_20079471_ChIP-ChIP_T-47D_Human3.64579695
3EZH2_22144423_ChIP-Seq_EOC_Human2.92410899
4TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.91715076
5CLOCK_20551151_ChIP-Seq_293T_Human2.88584080
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.77721905
7TBX20_22080862_ChIP-Seq_HEART_Mouse2.74241096
8TBX20_22328084_ChIP-Seq_HEART_Mouse2.74241096
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.69785355
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.60145691
11RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.59808903
12* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.52447303
13ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.50903720
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.44729884
15MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.33747607
16ESR1_21235772_ChIP-Seq_MCF-7_Human2.32731460
17TP63_17297297_ChIP-ChIP_HaCaT_Human2.24616267
18EP300_21415370_ChIP-Seq_HL-1_Mouse2.24064662
19THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.18601502
20ESR2_21235772_ChIP-Seq_MCF-7_Human2.18148609
21ZNF263_19887448_ChIP-Seq_K562_Human2.08103242
22TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.03090201
23CDX2_19796622_ChIP-Seq_MESCs_Mouse1.89130234
24CJUN_26792858_Chip-Seq_BT549_Human1.87706189
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.83742306
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.82777814
27WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.79571075
28EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.69670134
29P300_27058665_Chip-Seq_ZR-75-30cells_Human1.68813693
30KDM2B_26808549_Chip-Seq_DND41_Human1.65146255
31WT1_19549856_ChIP-ChIP_CCG9911_Human1.63040959
32ELK3_25401928_ChIP-Seq_HUVEC_Human1.59648080
33TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.58437640
34* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.57868178
35ZNF274_21170338_ChIP-Seq_K562_Hela1.54972579
36ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.54725746
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.52435747
38SUZ12_27294783_Chip-Seq_NPCs_Mouse1.51203675
39* ATF3_27146783_Chip-Seq_COLON_Human1.51143845
40HIF1A_21447827_ChIP-Seq_MCF-7_Human1.49842815
41TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.49383419
42SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.49263237
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.48782837
44KDM2B_26808549_Chip-Seq_SUP-B15_Human1.48291693
45SMC1_22415368_ChIP-Seq_MEFs_Mouse1.47664916
46CRX_20693478_ChIP-Seq_RETINA_Mouse1.47037516
47ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.46694306
48ZFP281_18757296_ChIP-ChIP_E14_Mouse1.46204074
49UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.44607476
50PPAR_26484153_Chip-Seq_NCI-H1993_Human1.43131886
51RACK7_27058665_Chip-Seq_MCF-7_Human1.42544681
52CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.42216908
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.41266257
54NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.37730330
55BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.36446600
56KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.36032681
57NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.35925400
58GBX2_23144817_ChIP-Seq_PC3_Human1.33374327
59TP53_16413492_ChIP-PET_HCT116_Human1.33082135
60* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.32014080
61BRD4_25478319_ChIP-Seq_HGPS_Human1.31726184
62CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.31114563
63CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.30149330
64GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30057032
65TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28858591
66NFIB_24661679_ChIP-Seq_LUNG_Mouse1.28643972
67TCF7_22412390_ChIP-Seq_EML_Mouse1.27580497
68SMC3_22415368_ChIP-Seq_MEFs_Mouse1.26433715
69NRF2_20460467_ChIP-Seq_MEFs_Mouse1.26117423
70NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.26117423
71OCT4_21477851_ChIP-Seq_ESCs_Mouse1.25981690
72EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.25216597
73CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.20824031
74MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.20221974
75CTCF_21964334_Chip-Seq_Bcells_Human1.20017529
76ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.19367421
77DNAJC2_21179169_ChIP-ChIP_NT2_Human1.18124082
78PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17651894
79LXR_22292898_ChIP-Seq_THP-1_Human1.17270461
80GATA4_21415370_ChIP-Seq_HL-1_Mouse1.16720029
81PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16374885
82UBF1/2_26484160_Chip-Seq_HMECs_Human1.16203678
83CTCF_27219007_Chip-Seq_Bcells_Human1.16170357
84CTCF_21964334_ChIP-Seq_BJAB-B_Human1.15287638
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.15016347
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.14585586
87KDM2B_26808549_Chip-Seq_K562_Human1.14249276
88TP53_18474530_ChIP-ChIP_U2OS_Human1.14221188
89GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.14204412
90TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.13727730
91ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.13521319
92PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.13462322
93CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.11945003
94FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.09912065
95CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.09552505
96SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09538024
97NR3C1_23031785_ChIP-Seq_PC12_Mouse1.07364717
98TP53_20018659_ChIP-ChIP_R1E_Mouse1.06504580
99P63_26484246_Chip-Seq_KERATINOCYTES_Human1.04650199
100NFE2_27457419_Chip-Seq_LIVER_Mouse1.04463537
101CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03939169
102* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.03921502
103RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03515423
104CREB1_26743006_Chip-Seq_LNCaP_Human1.03200098
105KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.02478400
106TP53_22127205_ChIP-Seq_IMR90_Human1.00808323
107RUNX1_27514584_Chip-Seq_MCF-7_Human1.00049767
108SA1_27219007_Chip-Seq_Bcells_Human1.00020473
109STAT6_21828071_ChIP-Seq_BEAS2B_Human0.99955217
110TDRD3_21172665_ChIP-Seq_MCF-7_Human0.98950243
111CTNNB1_20460455_ChIP-Seq_HCT116_Human0.98326020
112NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97400867
113TP53_23651856_ChIP-Seq_MEFs_Mouse0.97356972
114ZFP57_27257070_Chip-Seq_ESCs_Mouse0.95704167
115KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.95647713
116STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.95512078
117* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.93303887
118* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.93303887
119KDM2B_26808549_Chip-Seq_JURKAT_Human0.92379745
120PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.91802689
121EZH2_27294783_Chip-Seq_ESCs_Mouse0.91746993
122* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.91602909
123MTF2_20144788_ChIP-Seq_MESCs_Mouse0.91565067
124LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.91227950
125EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.91186043
126* SOX2_21211035_ChIP-Seq_LN229_Gbm0.90795746
127SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.90781068
128P53_22387025_ChIP-Seq_ESCs_Mouse0.90610696
129GATA2_21666600_ChIP-Seq_HMVEC_Human0.88479821
130EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88479321
131PPARA_22158963_ChIP-Seq_LIVER_Mouse0.87908089
132SOX9_24532713_ChIP-Seq_HFSC_Mouse0.87610999
133DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.87054219
134SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.85603940
135RUNX1_27457419_Chip-Seq_LIVER_Mouse0.84442027
136GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.82261476
137IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.80983926
138CBP_20019798_ChIP-Seq_JUKART_Human0.80983926
139MYC_27129775_Chip-Seq_CORNEA_Mouse0.80580272
140RAD21_21589869_ChIP-Seq_MESCs_Mouse0.79466948
141GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.78662973
142IGF1R_20145208_ChIP-Seq_DFB_Human0.78282185
143PIAS1_25552417_ChIP-Seq_VCAP_Human0.77986671
144KLF5_20875108_ChIP-Seq_MESCs_Mouse0.77227888
145AR_21572438_ChIP-Seq_LNCaP_Human0.76976803
146ZFX_18555785_Chip-Seq_ESCs_Mouse0.74962800
147NFI_21473784_ChIP-Seq_ESCs_Mouse0.73658614
148SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.73169264
149CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.72751468
150RNF2_18974828_ChIP-Seq_MESCs_Mouse0.72650346
151EZH2_18974828_ChIP-Seq_MESCs_Mouse0.72650346
152HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.72468462
153E2F1_18555785_Chip-Seq_ESCs_Mouse0.71682526
154CBX2_27304074_Chip-Seq_ESCs_Mouse0.71310537

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004145_abnormal_muscle_electrophysio6.44948789
2MP0000749_muscle_degeneration6.31139369
3MP0000751_myopathy5.77384992
4MP0000750_abnormal_muscle_regeneration4.82614336
5MP0000747_muscle_weakness4.59311166
6MP0000733_abnormal_muscle_development4.13848000
7MP0002106_abnormal_muscle_physiology3.98322695
8MP0003646_muscle_fatigue3.86478553
9MP0000759_abnormal_skeletal_muscle3.81751015
10MP0004087_abnormal_muscle_fiber3.58176168
11MP0005369_muscle_phenotype3.36483442
12MP0002269_muscular_atrophy3.31147082
13MP0002837_dystrophic_cardiac_calcinosis3.21367017
14MP0004036_abnormal_muscle_relaxation3.00409379
15MP0004233_abnormal_muscle_weight2.92997323
16MP0005451_abnormal_body_composition2.73399789
17MP0002108_abnormal_muscle_morphology2.55142912
18MP0004270_analgesia2.52966218
19MP0005620_abnormal_muscle_contractility2.43291336
20MP0004130_abnormal_muscle_cell2.19390059
21MP0004084_abnormal_cardiac_muscle2.06625666
22MP0005330_cardiomyopathy2.02339070
23MP0008438_abnormal_cutaneous_collagen1.90636391
24MP0003950_abnormal_plasma_membrane1.87942634
25MP0002234_abnormal_pharynx_morphology1.85129131
26MP0004215_abnormal_myocardial_fiber1.55840059
27MP0000013_abnormal_adipose_tissue1.48849367
28MP0002332_abnormal_exercise_endurance1.46761385
29MP0010030_abnormal_orbit_morphology1.46268257
30MP0002971_abnormal_brown_adipose1.42602660
31MP0010630_abnormal_cardiac_muscle1.40437350
32MP0001299_abnormal_eye_distance/1.39193045
33MP0003705_abnormal_hypodermis_morpholog1.36912987
34MP0005275_abnormal_skin_tensile1.36260011
35MP0002972_abnormal_cardiac_muscle1.35357314
36MP0001661_extended_life_span1.32980031
37MP0002163_abnormal_gland_morphology1.17710840
38MP0005623_abnormal_meninges_morphology1.14266381
39MP0004185_abnormal_adipocyte_glucose1.03257711
40MP0002877_abnormal_melanocyte_morpholog1.01952764
41MP0006036_abnormal_mitochondrial_physio0.93302237
42MP0005375_adipose_tissue_phenotype0.92076068
43MP0005666_abnormal_adipose_tissue0.92047139
44MP0003221_abnormal_cardiomyocyte_apopto0.91545340
45MP0005503_abnormal_tendon_morphology0.90777285
46MP0000003_abnormal_adipose_tissue0.88653206
47MP0004484_altered_response_of0.88172640
48MP0003137_abnormal_impulse_conducting0.87201725
49MP0003566_abnormal_cell_adhesion0.86237893
50MP0009780_abnormal_chondrocyte_physiolo0.81893624
51MP0005385_cardiovascular_system_phenoty0.80995878
52MP0001544_abnormal_cardiovascular_syste0.80995878
53MP0009250_abnormal_appendicular_skeleto0.78338619
54MP0001542_abnormal_bone_strength0.77917445
55MP0003279_aneurysm0.77679182
56MP0000762_abnormal_tongue_morphology0.73791680
57MP0002896_abnormal_bone_mineralization0.72174128
58MP0005266_abnormal_metabolism0.71000884
59MP0000372_irregular_coat_pigmentation0.70860505
60MP0003091_abnormal_cell_migration0.70659779
61MP0003045_fibrosis0.68507794
62MP0002114_abnormal_axial_skeleton0.65155624
63MP0008961_abnormal_basal_metabolism0.64034837
64MP0000767_abnormal_smooth_muscle0.63900752
65MP0005076_abnormal_cell_differentiation0.63471930
66MP0003828_pulmonary_edema0.62732560
67MP0006138_congestive_heart_failure0.61727147
68MP0004043_abnormal_pH_regulation0.61246570
69MP0002932_abnormal_joint_morphology0.60363527
70MP0000266_abnormal_heart_morphology0.59514676
71MP0001849_ear_inflammation0.58317251
72MP0004142_abnormal_muscle_tone0.57962619
73MP0004510_myositis0.57643439
74MP0002734_abnormal_mechanical_nocicepti0.57106961
75MP0003385_abnormal_body_wall0.56464701
76MP0008775_abnormal_heart_ventricle0.54170755
77MP0002822_catalepsy0.53713884
78MP0004134_abnormal_chest_morphology0.53579034
79MP0003879_abnormal_hair_cell0.52193002
80MP0002089_abnormal_postnatal_growth/wei0.50235665
81MP0002060_abnormal_skin_morphology0.49996042
82MP0004197_abnormal_fetal_growth/weight/0.49812345
83MP0003959_abnormal_lean_body0.49783384
84MP0001346_abnormal_lacrimal_gland0.48113741
85MP0001243_abnormal_dermal_layer0.47610856
86MP0003755_abnormal_palate_morphology0.47000894
87MP0002249_abnormal_larynx_morphology0.46758372
88MP0005670_abnormal_white_adipose0.45689863
89MP0006035_abnormal_mitochondrial_morpho0.45098681
90MP0002127_abnormal_cardiovascular_syste0.43026646
91MP0005023_abnormal_wound_healing0.42662474
92MP0005452_abnormal_adipose_tissue0.42333351
93MP0001943_abnormal_respiration0.42218203
94MP0002128_abnormal_blood_circulation0.42092098
95MP0005165_increased_susceptibility_to0.41870087
96MP0004858_abnormal_nervous_system0.41005161
97MP0000428_abnormal_craniofacial_morphol0.39189117
98MP0005508_abnormal_skeleton_morphology0.38996628
99MP0003948_abnormal_gas_homeostasis0.38311682
100MP0010368_abnormal_lymphatic_system0.38241878
101MP0001958_emphysema0.37794229
102MP0004272_abnormal_basement_membrane0.36614499
103MP0005379_endocrine/exocrine_gland_phen0.35233718
104MP0002168_other_aberrant_phenotype0.34769583
105MP0004085_abnormal_heartbeat0.34768465
106MP0002933_joint_inflammation0.34358024
107MP0005423_abnormal_somatic_nervous0.32929340
108MP0003806_abnormal_nucleotide_metabolis0.32324899
109MP0009115_abnormal_fat_cell0.31391787
110MP0005376_homeostasis/metabolism_phenot0.31119905
111MP0010352_gastrointestinal_tract_polyps0.30949355
112MP0000230_abnormal_systemic_arterial0.30475919
113MP0000163_abnormal_cartilage_morphology0.30420209
114MP0002078_abnormal_glucose_homeostasis0.29095292
115MP0008569_lethality_at_weaning0.28980987
116MP0005595_abnormal_vascular_smooth0.28042569
117MP0009672_abnormal_birth_weight0.27817813
118MP0003656_abnormal_erythrocyte_physiolo0.25642256
119MP0005584_abnormal_enzyme/coenzyme_acti0.20278713
120MP0009384_cardiac_valve_regurgitation0.19613508
121MP0000534_abnormal_ureter_morphology0.19136928
122MP0005319_abnormal_enzyme/_coenzyme0.18747219
123MP0005166_decreased_susceptibility_to0.18634952
124MP0003191_abnormal_cellular_cholesterol0.18306816
125MP0005187_abnormal_penis_morphology0.18233199

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)9.25003841
2Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)9.24001130
3Nemaline bodies (HP:0003798)8.02523313
4Type 1 muscle fiber predominance (HP:0003803)6.95732212
5Distal arthrogryposis (HP:0005684)6.23916742
6Round ear (HP:0100830)5.63254382
7Exercise-induced myalgia (HP:0003738)5.60072619
8Muscle fiber splitting (HP:0003555)5.55537977
9Myopathic facies (HP:0002058)5.44196293
10Ulnar deviation of the wrist (HP:0003049)5.34678518
11Fetal akinesia sequence (HP:0001989)5.29695297
12Malignant hyperthermia (HP:0002047)5.21660694
13Difficulty running (HP:0009046)5.06332761
14Fatigable weakness (HP:0003473)5.04609367
15Abnormality of the neuromuscular junction (HP:0003398)5.04609367
16Muscle hypertrophy of the lower extremities (HP:0008968)4.90330329
17Popliteal pterygium (HP:0009756)4.86838664
18Type 2 muscle fiber atrophy (HP:0003554)4.80885201
19Exercise-induced muscle cramps (HP:0003710)4.79594349
20Calf muscle hypertrophy (HP:0008981)4.74713077
21Difficulty climbing stairs (HP:0003551)4.69754786
22Calcaneovalgus deformity (HP:0001848)4.59446156
23Abnormality of the calf musculature (HP:0001430)4.44352274
24Increased connective tissue (HP:0009025)4.43934488
25Muscle fiber atrophy (HP:0100295)4.39126055
26Hyporeflexia of lower limbs (HP:0002600)4.33139189
27EMG: myopathic abnormalities (HP:0003458)4.30662049
28Deformed tarsal bones (HP:0008119)4.25344476
29Weak cry (HP:0001612)4.21965865
30Abnormality of placental membranes (HP:0011409)4.19328438
31Amniotic constriction ring (HP:0009775)4.19328438
32Absent phalangeal crease (HP:0006109)4.14878946
33Gowers sign (HP:0003391)3.79643498
34Abnormality of skeletal muscle fiber size (HP:0012084)3.72560985
35Aplasia of the musculature (HP:0100854)3.70250000
36Mildly elevated creatine phosphokinase (HP:0008180)3.69881683
37Distal lower limb amyotrophy (HP:0008944)3.55612464
38Abnormal finger flexion creases (HP:0006143)3.43653840
39Increased variability in muscle fiber diameter (HP:0003557)3.38211719
40Bulbar palsy (HP:0001283)3.29934076
41Neck muscle weakness (HP:0000467)3.24432175
42Easy fatigability (HP:0003388)3.20373612
43Myoglobinuria (HP:0002913)3.14434077
44Akinesia (HP:0002304)2.99225636
45Generalized muscle weakness (HP:0003324)2.98242343
46Myotonia (HP:0002486)2.93814912
47Abnormality of the calcaneus (HP:0008364)2.89209882
48Pelvic girdle muscle weakness (HP:0003749)2.82966709
49Shoulder girdle muscle weakness (HP:0003547)2.81714175
50Muscle stiffness (HP:0003552)2.79305120
51Frequent falls (HP:0002359)2.79250947
52Spinal rigidity (HP:0003306)2.76569100
53Abnormality of the musculature of the pelvis (HP:0001469)2.75638800
54Abnormality of the hip-girdle musculature (HP:0001445)2.75638800
55Lower limb amyotrophy (HP:0007210)2.74173383
56Thin ribs (HP:0000883)2.72576133
57Bundle branch block (HP:0011710)2.70819930
58Nonprogressive disorder (HP:0003680)2.68157139
59Slender build (HP:0001533)2.63620887
60Pterygium (HP:0001059)2.62381444
61Scapular winging (HP:0003691)2.58486141
62Rhabdomyolysis (HP:0003201)2.55865482
63Hip contracture (HP:0003273)2.50410468
64Limb-girdle muscle atrophy (HP:0003797)2.43848583
65Respiratory insufficiency due to muscle weakness (HP:0002747)2.39779310
66Subaortic stenosis (HP:0001682)2.39125301
67Abnormality of the left ventricular outflow tract (HP:0011103)2.39125301
68Distal lower limb muscle weakness (HP:0009053)2.34306683
69EMG: neuropathic changes (HP:0003445)2.30673421
70Limb-girdle muscle weakness (HP:0003325)2.28223956
71Lipoatrophy (HP:0100578)2.26831431
72Muscular dystrophy (HP:0003560)2.26770692
73Areflexia of lower limbs (HP:0002522)2.24936867
74Centrally nucleated skeletal muscle fibers (HP:0003687)2.21715685
75Sudden death (HP:0001699)2.20983981
76Rimmed vacuoles (HP:0003805)2.16186789
77Hypoplastic heart (HP:0001961)2.12447315
78Dilated cardiomyopathy (HP:0001644)2.11928024
79Cystic hygroma (HP:0000476)2.11295875
80Abnormality of the shoulder girdle musculature (HP:0001435)2.08523172
81Aplasia/Hypoplasia involving the musculature (HP:0001460)2.06562641
82Hypoplastic ischia (HP:0003175)2.04399917
83Facial diplegia (HP:0001349)1.99468016
84Long clavicles (HP:0000890)1.94703711
85Waddling gait (HP:0002515)1.94401352
86Proximal amyotrophy (HP:0007126)1.91463811
87Metatarsus adductus (HP:0001840)1.89318640
88Achilles tendon contracture (HP:0001771)1.86950618
89Progressive muscle weakness (HP:0003323)1.86830251
90Increased density of long bones (HP:0006392)1.83683544
91Asymmetric septal hypertrophy (HP:0001670)1.80896439
92Abnormality of the ischium (HP:0003174)1.76540186
93Arthrogryposis multiplex congenita (HP:0002804)1.76340815
94Ventricular tachycardia (HP:0004756)1.76267340
95Limited hip movement (HP:0008800)1.75614556
96Webbed neck (HP:0000465)1.73565240
97Hyperkalemia (HP:0002153)1.70718396
98Abnormalities of placenta or umbilical cord (HP:0001194)1.70208839
99Ulnar deviation of finger (HP:0009465)1.69596174
100Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.69153147
101Abnormality of the Achilles tendon (HP:0005109)1.68631854
102Abnormality of the foot musculature (HP:0001436)1.68220285
103Tarsal synostosis (HP:0008368)1.67378513
104Distal upper limb amyotrophy (HP:0007149)1.63968769
105Upper limb amyotrophy (HP:0009129)1.63968769
106Premature rupture of membranes (HP:0001788)1.63653439
107Heart block (HP:0012722)1.62006589
108Foot dorsiflexor weakness (HP:0009027)1.61539403
109Depressed nasal tip (HP:0000437)1.59709737
110Abnormal atrioventricular conduction (HP:0005150)1.56030923
111Generalized amyotrophy (HP:0003700)1.55620517
112Short palpebral fissure (HP:0012745)1.48398125
113Breech presentation (HP:0001623)1.47135160
114Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.46068588

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN7.32847351
2MUSK6.52090020
3TTN5.13845278
4PIK3CG4.05609425
5MOS3.71432904
6TRIB33.65720862
7PHKG13.45404444
8PHKG23.45404444
9NME12.56271829
10MAP2K32.05094021
11FGFR41.93995215
12PDK31.68766093
13PDK41.68766093
14MAP3K71.66182891
15DMPK1.56072412
16NEK11.50264320
17EPHB11.46134393
18MAPK121.38009472
19TRPM71.29730368
20PDK21.26929749
21CCNB11.25365679
22ILK1.23717101
23PKN21.19006630
24MAP2K11.14089305
25AKT21.10727226
26PIK3CA1.07492974
27PINK11.04860216
28RIPK10.99901796
29MAP3K100.99687822
30MARK10.93650592
31MAPKAPK30.92909641
32SIK10.90252339
33PAK40.82409583
34EPHA30.80018676
35MAP2K40.74168323
36BMX0.70808130
37PIM20.69571908
38EEF2K0.67826154
39MTOR0.67376878
40CDK150.66567299
41PDGFRA0.65794262
42MAP3K30.65094690
43CDK60.64513998
44PTK60.63315283
45ROCK20.63078426
46ROCK10.62129725
47ERBB30.62043614
48CDK180.60787596
49CDK11A0.60751153
50CDK140.60038211
51ERN10.59779350
52BCKDK0.59549985
53CDK120.58623564
54MAP2K60.55029735
55FER0.54232641
56LATS10.53988007
57PRKAA10.53197308
58NEK90.50714755
59DDR20.50446970
60MAP3K130.50366536
61LRRK20.48796339
62PRKAA20.47975555
63LIMK10.47756035
64CAMK2G0.47012410
65CAMK2B0.42837276
66TAOK20.42591314
67SGK30.39560110
68CAMK2A0.37976842
69MAP3K50.37614509
70MAPK110.37354029
71MAPK40.37329108
72PAK20.35213743
73FGFR10.33996517
74ICK0.33541907
75MAP3K120.33383287
76CAMK40.31502926
77ZAK0.31398914
78MYLK0.31012374
79PAK60.30499717
80LATS20.28805039
81MARK20.28410360
82RPS6KA30.28410139
83TAOK10.26929869
84PRKG10.26072269
85PKN10.26064795
86KSR20.25011237
87SGK20.24921981
88TIE10.24298735
89PRKACA0.24113409
90FGFR30.23655707
91MAPK70.22626494
92CAMK2D0.22148601
93MAP3K110.21868525
94PRKACB0.21534710
95MST1R0.20880271
96DYRK1B0.20715849
97PTK20.20153267
98EIF2AK30.19917125
99CAMK10.19425622
100PRKD30.19252862
101RPS6KB10.18648285
102SGK10.17843404
103PDPK10.17636684
104MAP3K10.17631300
105MAPK100.17564888
106MAPK130.16910967
107PTK2B0.16860478
108DAPK30.16799357
109TBK10.15232450
110TGFBR20.14726339
111STK110.14619135
112RET0.13403884
113STK240.12395813
114NLK0.11979572
115PRKD10.11829962
116CDK80.11424895
117MAP3K60.11218048
118HIPK20.10625411
119PAK30.10379735
120MELK0.10335397
121PBK0.09491189
122ZAP700.09163659
123RPS6KA10.08881469
124MAPK80.08725725
125ALK0.08693108
126ABL20.08581171
127GSK3A0.07669469
128MAPK90.07353154
129PDGFRB0.07068901
130MAPKAPK20.06938514
131ARAF0.06898488
132RPS6KB20.05767616
133PRKD20.04989891
134PRKG20.04768636
135PRKACG0.04567361

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054105.18727807
2Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054124.70619213
3Dilated cardiomyopathy_Homo sapiens_hsa054144.64873957
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.37555715
5Cardiac muscle contraction_Homo sapiens_hsa042603.25769542
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.45966582
7Viral myocarditis_Homo sapiens_hsa054162.10433146
8Starch and sucrose metabolism_Homo sapiens_hsa005002.00835168
9Oxytocin signaling pathway_Homo sapiens_hsa049211.97496133
10Glucagon signaling pathway_Homo sapiens_hsa049221.96237702
11Focal adhesion_Homo sapiens_hsa045101.96058664
12Insulin signaling pathway_Homo sapiens_hsa049101.94684178
13Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.88157252
14Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.83171998
15Insulin resistance_Homo sapiens_hsa049311.76089268
16Tight junction_Homo sapiens_hsa045301.74498006
17Circadian rhythm_Homo sapiens_hsa047101.72137621
18Adipocytokine signaling pathway_Homo sapiens_hsa049201.66333125
19Carbon metabolism_Homo sapiens_hsa012001.48011302
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.47027884
21Proteoglycans in cancer_Homo sapiens_hsa052051.46319804
22Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.46097312
23Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.39310891
24AMPK signaling pathway_Homo sapiens_hsa041521.38601800
25Propanoate metabolism_Homo sapiens_hsa006401.33164272
26ECM-receptor interaction_Homo sapiens_hsa045121.32018917
27Calcium signaling pathway_Homo sapiens_hsa040201.22256892
28Adherens junction_Homo sapiens_hsa045201.17174320
29cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10495735
30Amoebiasis_Homo sapiens_hsa051461.05478651
31Fatty acid degradation_Homo sapiens_hsa000711.05235135
32Central carbon metabolism in cancer_Homo sapiens_hsa052301.04809300
33FoxO signaling pathway_Homo sapiens_hsa040681.04612976
34HIF-1 signaling pathway_Homo sapiens_hsa040661.03901349
35MAPK signaling pathway_Homo sapiens_hsa040101.03157970
36Vascular smooth muscle contraction_Homo sapiens_hsa042701.01102870
37Longevity regulating pathway - mammal_Homo sapiens_hsa042110.99217904
38Regulation of actin cytoskeleton_Homo sapiens_hsa048100.95016128
39Biosynthesis of amino acids_Homo sapiens_hsa012300.93364866
40mTOR signaling pathway_Homo sapiens_hsa041500.92892797
41GnRH signaling pathway_Homo sapiens_hsa049120.89837331
42Leukocyte transendothelial migration_Homo sapiens_hsa046700.89303484
43Alzheimers disease_Homo sapiens_hsa050100.87243183
44Nitrogen metabolism_Homo sapiens_hsa009100.86193759
45Galactose metabolism_Homo sapiens_hsa000520.84230096
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.82848570
47Platelet activation_Homo sapiens_hsa046110.82697125
48Chronic myeloid leukemia_Homo sapiens_hsa052200.81475040
49Parkinsons disease_Homo sapiens_hsa050120.73466880
50Salmonella infection_Homo sapiens_hsa051320.72825701
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.70940066
52Renal cell carcinoma_Homo sapiens_hsa052110.70641286
53Dorso-ventral axis formation_Homo sapiens_hsa043200.70555402
54Pyruvate metabolism_Homo sapiens_hsa006200.69724657
55Fatty acid metabolism_Homo sapiens_hsa012120.68782895
56VEGF signaling pathway_Homo sapiens_hsa043700.67846133
57Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.64248613
58Arginine and proline metabolism_Homo sapiens_hsa003300.63975642
59Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63763274
60Long-term potentiation_Homo sapiens_hsa047200.62989067
61Gastric acid secretion_Homo sapiens_hsa049710.60989328
62Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60074115
63Fructose and mannose metabolism_Homo sapiens_hsa000510.59592097
64Huntingtons disease_Homo sapiens_hsa050160.58560825
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58441224
66Acute myeloid leukemia_Homo sapiens_hsa052210.56920031
67Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.56642333
68TGF-beta signaling pathway_Homo sapiens_hsa043500.55693725
69Insulin secretion_Homo sapiens_hsa049110.55584357
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.54775990
71Bladder cancer_Homo sapiens_hsa052190.53086993
72Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.52788793
73Notch signaling pathway_Homo sapiens_hsa043300.52751168
74Renin secretion_Homo sapiens_hsa049240.52552824
75Salivary secretion_Homo sapiens_hsa049700.50486775
76Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.45343665
77Phenylalanine metabolism_Homo sapiens_hsa003600.44482786
78Fatty acid biosynthesis_Homo sapiens_hsa000610.42984194
79Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42352525
80Glioma_Homo sapiens_hsa052140.41982760
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41942344
82PPAR signaling pathway_Homo sapiens_hsa033200.40765845
83Hippo signaling pathway_Homo sapiens_hsa043900.40758535
84Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40145626
85Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.39609802
86MicroRNAs in cancer_Homo sapiens_hsa052060.38671573
87Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.38574238
88Gap junction_Homo sapiens_hsa045400.38280019
89Cholinergic synapse_Homo sapiens_hsa047250.37196787
90Arginine biosynthesis_Homo sapiens_hsa002200.36016737
91Toxoplasmosis_Homo sapiens_hsa051450.35669782
92Aldosterone synthesis and secretion_Homo sapiens_hsa049250.33924919
93Circadian entrainment_Homo sapiens_hsa047130.33589988
94PI3K-Akt signaling pathway_Homo sapiens_hsa041510.33216380
95Malaria_Homo sapiens_hsa051440.32798843
96Estrogen signaling pathway_Homo sapiens_hsa049150.32481093
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.32371364
98Oxidative phosphorylation_Homo sapiens_hsa001900.32297090
99Melanogenesis_Homo sapiens_hsa049160.31877016
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.31399284
101beta-Alanine metabolism_Homo sapiens_hsa004100.30806563
102Long-term depression_Homo sapiens_hsa047300.30554856
103Melanoma_Homo sapiens_hsa052180.30222318
104Type II diabetes mellitus_Homo sapiens_hsa049300.29224696
105Pancreatic cancer_Homo sapiens_hsa052120.29184128
106Prion diseases_Homo sapiens_hsa050200.28080327
107Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.27975494
108Prostate cancer_Homo sapiens_hsa052150.26902158
109Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26333857
110Mineral absorption_Homo sapiens_hsa049780.25705133
111Sulfur metabolism_Homo sapiens_hsa009200.24837256
112Fatty acid elongation_Homo sapiens_hsa000620.24609959
113HTLV-I infection_Homo sapiens_hsa051660.23667295
114Pentose phosphate pathway_Homo sapiens_hsa000300.23309103
115Lysine degradation_Homo sapiens_hsa003100.22954171
116Protein digestion and absorption_Homo sapiens_hsa049740.21966265
117Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.21962674
118Small cell lung cancer_Homo sapiens_hsa052220.21821087
119Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.21504965
120Butanoate metabolism_Homo sapiens_hsa006500.20969568
121Tryptophan metabolism_Homo sapiens_hsa003800.17891035
122Regulation of autophagy_Homo sapiens_hsa041400.17613982
123cAMP signaling pathway_Homo sapiens_hsa040240.17407822
124Peroxisome_Homo sapiens_hsa041460.17351471
125Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.16633929
126Pancreatic secretion_Homo sapiens_hsa049720.16048934
127Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.15788769
128Sulfur relay system_Homo sapiens_hsa041220.15618290

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