ARRDC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.54401095
2positive regulation of gamma-delta T cell activation (GO:0046645)5.33910655
3ribosomal small subunit assembly (GO:0000028)5.26401979
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.75611075
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.75611075
6antigen processing and presentation of endogenous antigen (GO:0019883)4.52106669
7detection of bacterium (GO:0016045)4.36245026
8detection of other organism (GO:0098543)4.23851203
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.21139164
10positive regulation by organism of defense response of other organism involved in symbiotic interact4.21139164
11modulation by symbiont of host immune response (GO:0052553)4.21139164
12positive regulation by symbiont of host defense response (GO:0052509)4.21139164
13modulation by symbiont of host defense response (GO:0052031)4.21139164
14modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.21139164
15antigen processing and presentation via MHC class Ib (GO:0002475)4.07408763
16regulation of gamma-delta T cell differentiation (GO:0045586)4.01773715
17macrophage activation involved in immune response (GO:0002281)3.86498711
18mannose metabolic process (GO:0006013)3.79984240
19regulation of gamma-delta T cell activation (GO:0046643)3.77052631
20positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.69672001
21immunoglobulin mediated immune response (GO:0016064)3.69074635
22type I interferon signaling pathway (GO:0060337)3.65184853
23cellular response to type I interferon (GO:0071357)3.65184853
24response to type I interferon (GO:0034340)3.65048368
25NIK/NF-kappaB signaling (GO:0038061)3.63975086
26response to interferon-beta (GO:0035456)3.61382811
27DNA deamination (GO:0045006)3.56053876
28positive regulation of Cdc42 GTPase activity (GO:0043089)3.53605977
29positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.47686581
30regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.46417516
31positive regulation of B cell differentiation (GO:0045579)3.45568593
32viral transcription (GO:0019083)3.44756836
33myeloid dendritic cell activation (GO:0001773)3.40252035
34detection of external biotic stimulus (GO:0098581)3.37067620
35regulation of B cell differentiation (GO:0045577)3.28463094
36regulation of interleukin-12 biosynthetic process (GO:0045075)3.28353214
37cellular response to interferon-beta (GO:0035458)3.27676333
38defense response to protozoan (GO:0042832)3.26065939
39regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.25970667
40translational termination (GO:0006415)3.25633056
41GDP-mannose metabolic process (GO:0019673)3.24530413
42neutrophil activation involved in immune response (GO:0002283)3.22563515
43regulation of mast cell degranulation (GO:0043304)3.22316283
44mast cell activation (GO:0045576)3.22000918
45Arp2/3 complex-mediated actin nucleation (GO:0034314)3.21295457
46regulation of RIG-I signaling pathway (GO:0039535)3.19340641
47B cell mediated immunity (GO:0019724)3.18703045
48regulation of leukocyte degranulation (GO:0043300)3.18254355
49regulation of myeloid leukocyte mediated immunity (GO:0002886)3.16537102
50thymic T cell selection (GO:0045061)3.16086746
51regulation of dendritic cell antigen processing and presentation (GO:0002604)3.15061930
52regulation of regulatory T cell differentiation (GO:0045589)3.12668060
53interferon-gamma-mediated signaling pathway (GO:0060333)3.11874172
54myeloid dendritic cell differentiation (GO:0043011)3.11344209
55germinal center formation (GO:0002467)3.10150515
56regulation of B cell receptor signaling pathway (GO:0050855)3.08776782
57response to protozoan (GO:0001562)3.08367715
58SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.98809516
59interferon-gamma secretion (GO:0072643)2.96955173
60platelet dense granule organization (GO:0060155)2.95322377
61response to muramyl dipeptide (GO:0032495)2.94756057
62negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.93923593
63B cell receptor signaling pathway (GO:0050853)2.93823395
64response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.93782925
65response to host immune response (GO:0052572)2.93782925
66T cell homeostasis (GO:0043029)2.90030020
67cellular extravasation (GO:0045123)2.88160883
68translational elongation (GO:0006414)2.88126956
69cotranslational protein targeting to membrane (GO:0006613)2.88120887
70positive regulation of humoral immune response (GO:0002922)2.87832392
71detection of biotic stimulus (GO:0009595)2.87559723
72protein targeting to ER (GO:0045047)2.87492653
73ribosomal small subunit biogenesis (GO:0042274)2.86840914
74T cell selection (GO:0045058)2.86141720
75negative regulation of erythrocyte differentiation (GO:0045647)2.86120595
76regulation of type I interferon-mediated signaling pathway (GO:0060338)2.83594269
77myeloid cell activation involved in immune response (GO:0002275)2.81717996
78negative regulation of lymphocyte mediated immunity (GO:0002707)2.81439316
79response to interferon-alpha (GO:0035455)2.81184606
80response to host defenses (GO:0052200)2.81040970
81response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.81040970
82response to host (GO:0075136)2.81040970
83regulation of mast cell activation involved in immune response (GO:0033006)2.80580325
84positive regulation of antigen processing and presentation (GO:0002579)2.78048416
85granulocyte activation (GO:0036230)2.76671151
86hepatocyte apoptotic process (GO:0097284)2.74878152
87protein localization to endoplasmic reticulum (GO:0070972)2.74159589
88maturation of SSU-rRNA (GO:0030490)2.71121930
89positive regulation of interferon-alpha production (GO:0032727)2.70635407
90negative thymic T cell selection (GO:0045060)2.70342857
91establishment of protein localization to endoplasmic reticulum (GO:0072599)2.69854383
92definitive hemopoiesis (GO:0060216)2.68998742
93positive thymic T cell selection (GO:0045059)2.68832958
94negative regulation of leukocyte mediated immunity (GO:0002704)2.68650161
95positive regulation of natural killer cell differentiation (GO:0032825)2.68572720
96lipopolysaccharide-mediated signaling pathway (GO:0031663)2.68240287
97positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.66959397
98regulation of regulated secretory pathway (GO:1903305)2.66753059
99negative T cell selection (GO:0043383)2.66373046
100neutrophil activation (GO:0042119)2.64994516
101dendritic cell differentiation (GO:0097028)2.64707404
102mature B cell differentiation involved in immune response (GO:0002313)2.63634594
103lymph node development (GO:0048535)2.63381525
104macrophage activation (GO:0042116)2.62942696
105regulation of necroptotic process (GO:0060544)2.62911490
106telomere maintenance via semi-conservative replication (GO:0032201)2.61251986
107negative regulation of interleukin-8 production (GO:0032717)2.60753607
108regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.59787006
109regulation of T cell receptor signaling pathway (GO:0050856)2.59740571
110negative regulation of interleukin-12 production (GO:0032695)2.59639406
111viral life cycle (GO:0019058)2.58894338
112necroptotic process (GO:0070266)2.58767025
113response to peptidoglycan (GO:0032494)2.58566047
114T cell migration (GO:0072678)2.57927038
115negative regulation of innate immune response (GO:0045824)2.57479785
116regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.57052388
117regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.57047466
118G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.56980244
119negative regulation of cell size (GO:0045792)2.55650951
120regulation of T cell mediated cytotoxicity (GO:0001914)2.55526549
121epithelial cell differentiation involved in prostate gland development (GO:0060742)2.54478943
122regulation of interferon-alpha production (GO:0032647)2.52722133
123positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.52618952
124positive regulation of granulocyte differentiation (GO:0030854)2.52594924
125regulation of T-helper 2 cell differentiation (GO:0045628)2.52023773
126detection of molecule of bacterial origin (GO:0032490)2.51389011
127nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.50743065
128lymphoid progenitor cell differentiation (GO:0002320)2.50476683
129megakaryocyte development (GO:0035855)2.50439710
130negative regulation of cell killing (GO:0031342)2.50183428
131negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.50183428
132positive regulation of histone deacetylation (GO:0031065)2.50041567
133cellular response to virus (GO:0098586)2.48784542
134mast cell degranulation (GO:0043303)2.47943297
135mast cell activation involved in immune response (GO:0002279)2.47943297
136interferon-gamma production (GO:0032609)2.47531851
137telomere maintenance via recombination (GO:0000722)2.46801723
138pinocytosis (GO:0006907)2.46628389
139regulation of ARF GTPase activity (GO:0032312)2.45832556
140positive regulation of T cell mediated cytotoxicity (GO:0001916)2.45548540
141respiratory burst (GO:0045730)2.44899236
142regulation of natural killer cell differentiation (GO:0032823)2.44767973
143regulation of interferon-beta biosynthetic process (GO:0045357)2.44207019
144regulation of tumor necrosis factor superfamily cytokine production (GO:1903555)2.42690153
145natural killer cell activation (GO:0030101)2.42647053
146negative regulation of phagocytosis (GO:0050765)2.42312904
147regulation of defense response to virus by virus (GO:0050690)2.42064453
148actin nucleation (GO:0045010)2.42058692
149leukocyte aggregation (GO:0070486)2.41861627
150endosome to pigment granule transport (GO:0043485)2.41441693
151endosome to melanosome transport (GO:0035646)2.41441693
152sequestering of actin monomers (GO:0042989)2.40999937
153regulation of antigen processing and presentation (GO:0002577)2.39588873
154positive regulation of tumor necrosis factor production (GO:0032760)2.39549901
155positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.39235660
156negative regulation of interleukin-6 production (GO:0032715)2.37057738
157activation of Rac GTPase activity (GO:0032863)2.36651842
158modulation by virus of host process (GO:0019054)2.35522860
159regulation of tumor necrosis factor production (GO:0032680)2.34964233

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.40021382
2E2F7_22180533_ChIP-Seq_HELA_Human4.23511873
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.66680694
4IRF8_21731497_ChIP-ChIP_J774_Mouse3.18048055
5MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.14512874
6SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.90890982
7SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.81986335
8SCL_19346495_ChIP-Seq_HPC-7_Human2.80334551
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.73696807
10LXR_22292898_ChIP-Seq_THP-1_Human2.71169572
11FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.53852123
12RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.53652585
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.53065902
14FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.52575592
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.51108266
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.37927868
17STAT4_19710469_ChIP-ChIP_TH1__Mouse2.35310103
18SPI1_23547873_ChIP-Seq_NB4_Human2.34827608
19KDM2B_26808549_Chip-Seq_SUP-B15_Human2.31782965
20EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.29580831
21KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.27549447
22RACK7_27058665_Chip-Seq_MCF-7_Human2.26987045
23TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.26452724
24EGR1_19374776_ChIP-ChIP_THP-1_Human2.21044453
25ELK3_25401928_ChIP-Seq_HUVEC_Human2.20895599
26NOTCH1_21737748_ChIP-Seq_TLL_Human2.20793541
27TP63_17297297_ChIP-ChIP_HaCaT_Human2.20434175
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.17897684
29THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.15047910
30VDR_21846776_ChIP-Seq_THP-1_Human2.13326682
31MYC_22102868_ChIP-Seq_BL_Human2.12977802
32BP1_19119308_ChIP-ChIP_Hs578T_Human2.08593407
33SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.06738683
34ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.06030384
35IRF8_27001747_Chip-Seq_BMDM_Mouse2.05658513
36KDM2B_26808549_Chip-Seq_DND41_Human2.02743069
37GATA1_22025678_ChIP-Seq_K562_Human2.02004765
38MYB_26560356_Chip-Seq_TH2_Human2.00864836
39NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.95827753
40SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.92394703
41MAF_26560356_Chip-Seq_TH1_Human1.89997044
42P68_20966046_ChIP-Seq_HELA_Human1.88801471
43RARG_19884340_ChIP-ChIP_MEFs_Mouse1.87867575
44STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.87539745
45MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.87351018
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.86465241
47ERG_20887958_ChIP-Seq_HPC-7_Mouse1.85239336
48RUNX1_22412390_ChIP-Seq_EML_Mouse1.83933636
49NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.82269369
50ESR2_21235772_ChIP-Seq_MCF-7_Human1.80819924
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.80513884
52MYC_18555785_ChIP-Seq_MESCs_Mouse1.79998703
53MYB_26560356_Chip-Seq_TH1_Human1.79475782
54SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.76553068
55LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.76461882
56FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.72242123
57VDR_24763502_ChIP-Seq_THP-1_Human1.69832937
58GABP_17652178_ChIP-ChIP_JURKAT_Human1.69567195
59VDR_23849224_ChIP-Seq_CD4+_Human1.65219022
60BCOR_27268052_Chip-Seq_Bcells_Human1.64757914
61LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.61508225
62TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.61088177
63BCL6_27268052_Chip-Seq_Bcells_Human1.60840305
64UTX_26944678_Chip-Seq_JUKART_Human1.58845383
65CTCF_27219007_Chip-Seq_ERYTHROID_Human1.56721003
66EST1_17652178_ChIP-ChIP_JURKAT_Human1.55771083
67TET1_21451524_ChIP-Seq_MESCs_Mouse1.55482824
68PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.55412612
69JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.54685273
70FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.54255263
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.53875801
72SA1_27219007_Chip-Seq_ERYTHROID_Human1.52500172
73STAT6_21828071_ChIP-Seq_BEAS2B_Human1.52385406
74KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.52255042
75SMC4_20622854_ChIP-Seq_HELA_Human1.49527352
76GATA1_22383799_ChIP-Seq_G1ME_Mouse1.49086446
77BRD4_27068464_Chip-Seq_AML-cells_Mouse1.47844990
78NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.47587894
79ELF1_20517297_ChIP-Seq_JURKAT_Human1.45731213
80FOXP3_21729870_ChIP-Seq_TREG_Human1.45697852
81* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.44470452
82FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.42545613
83TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.41617852
84GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.41222711
85RUNX_20019798_ChIP-Seq_JUKART_Human1.40923577
86MYC_18358816_ChIP-ChIP_MESCs_Mouse1.40124973
87E2F4_17652178_ChIP-ChIP_JURKAT_Human1.39593210
88RUNX1_27514584_Chip-Seq_MCF-7_Human1.38464206
89E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.38141467
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.37532996
91CIITA_25753668_ChIP-Seq_RAJI_Human1.33359220
92DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.32695212
93MAF_26560356_Chip-Seq_TH2_Human1.31088559
94SRF_21415370_ChIP-Seq_HL-1_Mouse1.29522109
95ETS1_20019798_ChIP-Seq_JURKAT_Human1.29004744
96STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.28710723
97EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28687256
98CREB1_26743006_Chip-Seq_LNCaP_Human1.27332611
99SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.26231741
100TCF7_22412390_ChIP-Seq_EML_Mouse1.25767453
101KDM2B_26808549_Chip-Seq_K562_Human1.25279430
102NCOR1_26117541_ChIP-Seq_K562_Human1.24993510
103ESR1_20079471_ChIP-ChIP_T-47D_Human1.23961571
104RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.23337685
105SPI1_23127762_ChIP-Seq_K562_Human1.23275644
106KDM2B_26808549_Chip-Seq_JURKAT_Human1.23166216
107SRY_22984422_ChIP-ChIP_TESTIS_Rat1.23044731
108KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.22807046
109E2F1_20622854_ChIP-Seq_HELA_Human1.22497664
110ZNF263_19887448_ChIP-Seq_K562_Human1.22456238
111KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.21916604
112MYC_19079543_ChIP-ChIP_MESCs_Mouse1.21160675
113CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.20360254
114* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.19907332
115PPARA_22158963_ChIP-Seq_LIVER_Mouse1.19734284
116* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.19423465
117ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18587358
118SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.17881827
119UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.17833147
120GATA3_27048872_Chip-Seq_THYMUS_Human1.17828740
121PHF8_20622854_ChIP-Seq_HELA_Human1.17475244
122CTCF_26484167_Chip-Seq_Bcells_Mouse1.17448689
123ESR1_21235772_ChIP-Seq_MCF-7_Human1.17397451
124VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16574504
125* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16118874
126XRN2_22483619_ChIP-Seq_HELA_Human1.15742497
127CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14695649
128CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14555672
129MYC_19030024_ChIP-ChIP_MESCs_Mouse1.13257910
130P63_26484246_Chip-Seq_KERATINOCYTES_Human1.12749837
131CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.11485982
132* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10828594
133CTCF_21964334_Chip-Seq_Bcells_Human1.10588109
134CTCF_21964334_ChIP-Seq_BJAB-B_Human1.10565919
135* ATF3_27146783_Chip-Seq_COLON_Human1.08460523
136E2F1_18555785_ChIP-Seq_MESCs_Mouse1.07971545
137PU.1_20513432_ChIP-Seq_Bcells_Mouse1.07769021
138KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.07726236
139TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.07045802
140GABP_19822575_ChIP-Seq_HepG2_Human1.06909527
141DCP1A_22483619_ChIP-Seq_HELA_Human1.06304495
142RARB_24833708_ChIP-Seq_LIVER_Mouse1.06193947
143KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.05342836
144PU_27001747_Chip-Seq_BMDM_Mouse1.05330902
145* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.03348169
146CREB1_15753290_ChIP-ChIP_HEK293T_Human1.02033389
147GATA1_19941827_ChIP-Seq_MEL_Mouse1.00887983
148FOXM1_23109430_ChIP-Seq_U2OS_Human1.00378433
149HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.00050288
150HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99542732
151SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97281657
152CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.96374183
153E2F1_21310950_ChIP-Seq_MCF-7_Human0.96210356
154ELK1_19687146_ChIP-ChIP_HELA_Human0.95839867
155CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95778753
156GATA3_26560356_Chip-Seq_TH2_Human0.94263250
157PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92946189
158FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92511313
159CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91159614

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.05955321
2MP0005671_abnormal_response_to3.35418220
3MP0009785_altered_susceptibility_to3.24880012
4MP0000685_abnormal_immune_system3.24680281
5MP0002396_abnormal_hematopoietic_system3.09338773
6MP0003763_abnormal_thymus_physiology2.72977290
7MP0003436_decreased_susceptibility_to2.70367001
8MP0001800_abnormal_humoral_immune2.61975908
9MP0002148_abnormal_hypersensitivity_rea2.60256861
10MP0005025_abnormal_response_to2.57247187
11MP0005000_abnormal_immune_tolerance2.52313221
12MP0002452_abnormal_antigen_presenting2.48069397
13MP0005387_immune_system_phenotype2.44424240
14MP0001790_abnormal_immune_system2.44424240
15MP0002420_abnormal_adaptive_immunity2.41998025
16MP0002723_abnormal_immune_serum2.40855445
17MP0001819_abnormal_immune_cell2.40492303
18MP0002166_altered_tumor_susceptibility2.39245409
19MP0005451_abnormal_body_composition2.38364058
20MP0008260_abnormal_autophagy2.38094705
21MP0003172_abnormal_lysosome_physiology2.32235957
22MP0002398_abnormal_bone_marrow2.27184503
23MP0005464_abnormal_platelet_physiology2.26862568
24MP0002419_abnormal_innate_immunity2.24164866
25MP0003724_increased_susceptibility_to2.22039344
26MP0005397_hematopoietic_system_phenotyp2.19266403
27MP0001545_abnormal_hematopoietic_system2.19266403
28MP0010155_abnormal_intestine_physiology2.13284308
29MP0001873_stomach_inflammation2.11142102
30MP0004381_abnormal_hair_follicle2.06386007
31MP0004808_abnormal_hematopoietic_stem2.04236065
32MP0000716_abnormal_immune_system2.03074491
33MP0003866_abnormal_defecation2.02940504
34MP0002006_tumorigenesis2.01727686
35MP0003693_abnormal_embryo_hatching2.00524077
36MP0000490_abnormal_crypts_of1.98512438
37MP0005083_abnormal_biliary_tract1.97138003
38MP0009333_abnormal_splenocyte_physiolog1.93354165
39MP0002796_impaired_skin_barrier1.93032546
40MP0002405_respiratory_system_inflammati1.91860247
41MP0000689_abnormal_spleen_morphology1.90684460
42MP0003705_abnormal_hypodermis_morpholog1.87723406
43MP0005174_abnormal_tail_pigmentation1.86444456
44MP0002722_abnormal_immune_system1.85998550
45MP0002429_abnormal_blood_cell1.77954932
46MP0000465_gastrointestinal_hemorrhage1.71150909
47MP0001853_heart_inflammation1.68331457
48MP0005075_abnormal_melanosome_morpholog1.67538040
49MP0001845_abnormal_inflammatory_respons1.64586689
50MP0004947_skin_inflammation1.61077007
51MP0003453_abnormal_keratinocyte_physiol1.60817593
52MP0005310_abnormal_salivary_gland1.58142527
53MP0000703_abnormal_thymus_morphology1.51940509
54MP0009840_abnormal_foam_cell1.51690246
55MP0004185_abnormal_adipocyte_glucose1.49840698
56MP0005076_abnormal_cell_differentiation1.47708121
57MP0005058_abnormal_lysosome_morphology1.45501808
58MP0004510_myositis1.41583728
59MP0003303_peritoneal_inflammation1.39362044
60MP0010094_abnormal_chromosome_stability1.37495501
61MP0005501_abnormal_skin_physiology1.35581450
62MP0008469_abnormal_protein_level1.34072601
63MP0008007_abnormal_cellular_replicative1.29784139
64MP0003806_abnormal_nucleotide_metabolis1.24275890
65MP0004858_abnormal_nervous_system1.23625103
66MP0003191_abnormal_cellular_cholesterol1.22847868
67MP0000858_altered_metastatic_potential1.22699251
68MP0006082_CNS_inflammation1.22338891
69MP0005409_darkened_coat_color1.22038629
70MP0001849_ear_inflammation1.21702771
71MP0002019_abnormal_tumor_incidence1.20657646
72MP0009278_abnormal_bone_marrow1.18289608
73MP0003077_abnormal_cell_cycle1.16437399
74MP0001533_abnormal_skeleton_physiology1.16192931
75MP0003943_abnormal_hepatobiliary_system1.15485540
76MP0003300_gastrointestinal_ulcer1.14405748
77MP0008058_abnormal_DNA_repair1.12698868
78MP0002095_abnormal_skin_pigmentation1.11398824
79MP0003183_abnormal_peptide_metabolism1.10672373
80MP0001986_abnormal_taste_sensitivity1.09656156
81MP0003075_altered_response_to1.07900090
82MP0000678_abnormal_parathyroid_gland1.07368328
83MP0002138_abnormal_hepatobiliary_system1.03309956
84MP0001851_eye_inflammation1.02927875
85MP0005666_abnormal_adipose_tissue1.02490351
86MP0008057_abnormal_DNA_replication1.01204757
87MP0002098_abnormal_vibrissa_morphology0.97966695
88MP0004782_abnormal_surfactant_physiolog0.97377295
89MP0002998_abnormal_bone_remodeling0.93579650
90MP0009931_abnormal_skin_appearance0.92669115
91MP0002132_abnormal_respiratory_system0.92609456
92MP0004957_abnormal_blastocyst_morpholog0.92133835
93MP0001216_abnormal_epidermal_layer0.91413354
94MP0010352_gastrointestinal_tract_polyps0.89648620
95MP0009764_decreased_sensitivity_to0.88241873
96MP0002163_abnormal_gland_morphology0.87822971
97MP0000371_diluted_coat_color0.86772901
98MP0000015_abnormal_ear_pigmentation0.86632843
99MP0001765_abnormal_ion_homeostasis0.84208332
100MP0003448_altered_tumor_morphology0.83279058
101MP0002009_preneoplasia0.83239773
102MP0003045_fibrosis0.83048409
103MP0005360_urolithiasis0.82861701
104MP0002933_joint_inflammation0.82062758
105MP0003566_abnormal_cell_adhesion0.81774378
106MP0003111_abnormal_nucleus_morphology0.80361464
107MP0005166_decreased_susceptibility_to0.79339721
108MP0000372_irregular_coat_pigmentation0.79311498
109MP0001663_abnormal_digestive_system0.79255426
110MP0000313_abnormal_cell_death0.77866956
111MP0000343_altered_response_to0.76467796
112MP0003186_abnormal_redox_activity0.75326469
113MP0000477_abnormal_intestine_morphology0.74866368
114MP0005375_adipose_tissue_phenotype0.74573725
115MP0009763_increased_sensitivity_to0.72423891
116MP0003828_pulmonary_edema0.72420594
117MP0003786_premature_aging0.71823889
118MP0009379_abnormal_foot_pigmentation0.71655876
119MP0000470_abnormal_stomach_morphology0.70649748
120MP0004147_increased_porphyrin_level0.70346198
121MP0002277_abnormal_respiratory_mucosa0.70188146
122MP0005390_skeleton_phenotype0.69508139
123MP0004264_abnormal_extraembryonic_tissu0.67944781
124MP0005220_abnormal_exocrine_pancreas0.67502264
125MP0002136_abnormal_kidney_physiology0.66541807
126MP0001348_abnormal_lacrimal_gland0.66325163
127MP0008874_decreased_physiological_sensi0.65982589
128MP0008004_abnormal_stomach_pH0.64569174
129MP0003656_abnormal_erythrocyte_physiolo0.63802424
130MP0000681_abnormal_thyroid_gland0.60772280
131MP0002254_reproductive_system_inflammat0.60427295
132MP0006054_spinal_hemorrhage0.59783685
133MP0002877_abnormal_melanocyte_morpholog0.58470207
134MP0010234_abnormal_vibrissa_follicle0.56660681

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)4.92284493
2Recurrent abscess formation (HP:0002722)4.83157451
3Thrombocytosis (HP:0001894)4.29348879
4Recurrent bacterial skin infections (HP:0005406)4.27563932
5Myositis (HP:0100614)4.24097179
6Eczematoid dermatitis (HP:0000976)4.01178915
7IgM deficiency (HP:0002850)3.97720449
8Petechiae (HP:0000967)3.94747842
9Aplastic anemia (HP:0001915)3.91218982
10Chronic otitis media (HP:0000389)3.76379498
11Recurrent fungal infections (HP:0002841)3.70949874
12Recurrent viral infections (HP:0004429)3.57262466
13Abnormal delayed hypersensitivity skin test (HP:0002963)3.42090808
14Panhypogammaglobulinemia (HP:0003139)3.39352408
15Pustule (HP:0200039)3.37946930
16Reticulocytopenia (HP:0001896)3.30705940
17Mediastinal lymphadenopathy (HP:0100721)3.22705284
18Abnormality of macrophages (HP:0004311)3.21936819
19Abnormality of T cell physiology (HP:0011840)3.21541971
20Agammaglobulinemia (HP:0004432)3.20890989
21Abnormality of cells of the erythroid lineage (HP:0012130)3.18952785
22Abnormal number of erythroid precursors (HP:0012131)3.17789513
23Recurrent bronchitis (HP:0002837)3.15340030
24Dysostosis multiplex (HP:0000943)3.13891142
25Thin bony cortex (HP:0002753)3.13264975
26Vacuolated lymphocytes (HP:0001922)3.13240590
27Prolonged bleeding time (HP:0003010)3.11206500
28Recurrent skin infections (HP:0001581)3.09223316
29Meningitis (HP:0001287)3.05547922
30Abnormality of T cells (HP:0002843)3.01525964
31Recurrent cutaneous fungal infections (HP:0011370)2.94763351
32Chronic mucocutaneous candidiasis (HP:0002728)2.94763351
33Abnormality of the nasal mucosa (HP:0000433)2.86266982
34Abnormality of mucopolysaccharide metabolism (HP:0011020)2.82981685
35Abnormality of polysaccharide metabolism (HP:0011012)2.82981685
36Abnormality of glycosaminoglycan metabolism (HP:0004371)2.82981685
37Orchitis (HP:0100796)2.81229130
38Cellulitis (HP:0100658)2.81012066
39Interstitial pulmonary disease (HP:0006530)2.80990146
40Gastrointestinal inflammation (HP:0004386)2.76572155
41Hemorrhage of the eye (HP:0011885)2.75730406
42Vasculitis (HP:0002633)2.74775170
43Inflammation of the large intestine (HP:0002037)2.73961735
44Urinary glycosaminoglycan excretion (HP:0003541)2.71217809
45Mucopolysacchariduria (HP:0008155)2.71217809
46Nasal polyposis (HP:0100582)2.70452508
47IgG deficiency (HP:0004315)2.66788389
48Retrobulbar optic neuritis (HP:0100654)2.63673853
49Optic neuritis (HP:0100653)2.63673853
50Lymphopenia (HP:0001888)2.62670337
51Colitis (HP:0002583)2.61287477
52Gastrointestinal infarctions (HP:0005244)2.58939652
53Recurrent gram-negative bacterial infections (HP:0005420)2.58908224
54Autoimmune thrombocytopenia (HP:0001973)2.58480138
55Abnormality of cells of the lymphoid lineage (HP:0012140)2.57781315
56Increased serum ferritin (HP:0003281)2.56562082
57Epistaxis (HP:0000421)2.56045544
58Type I transferrin isoform profile (HP:0003642)2.55961523
59Periodontitis (HP:0000704)2.52325783
60Abnormality of T cell number (HP:0011839)2.49060140
61Obstructive lung disease (HP:0006536)2.47656498
62Chronic obstructive pulmonary disease (HP:0006510)2.47656498
63Abnormality of glycolipid metabolism (HP:0010969)2.45537806
64Abnormality of liposaccharide metabolism (HP:0010968)2.45537806
65Abnormality of glycosphingolipid metabolism (HP:0004343)2.45537806
66Spontaneous hematomas (HP:0007420)2.42683881
67J-shaped sella turcica (HP:0002680)2.42117413
68T lymphocytopenia (HP:0005403)2.41496839
69Distal lower limb muscle weakness (HP:0009053)2.40801622
70Thyroiditis (HP:0100646)2.40543633
71Loss of speech (HP:0002371)2.39476418
72Chest pain (HP:0100749)2.38531013
73Encephalitis (HP:0002383)2.38367346
74Abnormality of the prostate (HP:0008775)2.37954382
75Malnutrition (HP:0004395)2.35969647
76Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.34904987
77Lymphoma (HP:0002665)2.34443667
78Urticaria (HP:0001025)2.33065857
79Stomatitis (HP:0010280)2.32652432
80Broad face (HP:0000283)2.32544526
81B lymphocytopenia (HP:0010976)2.30927862
82Abnormality of B cell number (HP:0010975)2.30927862
83Leukocytosis (HP:0001974)2.30765682
84Pallor (HP:0000980)2.30667741
85Abnormal platelet function (HP:0011869)2.30181965
86Impaired platelet aggregation (HP:0003540)2.30181965
87Severe combined immunodeficiency (HP:0004430)2.29172340
88Abnormality of the fingertips (HP:0001211)2.24462301
89Increased neuronal autofluorescent lipopigment (HP:0002074)2.23345992
90Gastrointestinal stroma tumor (HP:0100723)2.23006126
91Flat acetabular roof (HP:0003180)2.20700256
92Acute myeloid leukemia (HP:0004808)2.20548090
93Neutropenia (HP:0001875)2.19800214
94Hypertensive crisis (HP:0100735)2.19503960
95Granulocytopenia (HP:0001913)2.18473814
96Type 2 muscle fiber atrophy (HP:0003554)2.18386850
97Hepatosplenomegaly (HP:0001433)2.17886145
98Reduced antithrombin III activity (HP:0001976)2.17750124
99Combined immunodeficiency (HP:0005387)2.17058984
100Hemoptysis (HP:0002105)2.16683944
101Osteomyelitis (HP:0002754)2.15974152
102Cervical subluxation (HP:0003308)2.15719120
103Amyloidosis (HP:0011034)2.15300961
104Myelodysplasia (HP:0002863)2.14563243
105Hypochromic anemia (HP:0001931)2.13158576
106Increased IgE level (HP:0003212)2.12830682
107Chronic diarrhea (HP:0002028)2.12675843
108Muscle fiber atrophy (HP:0100295)2.12205469
109Abnormality of iron homeostasis (HP:0011031)2.09163945
110Pulmonary infiltrates (HP:0002113)2.08653819
111Testicular atrophy (HP:0000029)2.06719116
112Abnormality of eosinophils (HP:0001879)2.06498101
113Pili torti (HP:0003777)2.04838461
114Gingivitis (HP:0000230)2.04305584
115Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.03590384
116Abnormal protein N-linked glycosylation (HP:0012347)2.03590384
117Abnormal protein glycosylation (HP:0012346)2.03590384
118Abnormal glycosylation (HP:0012345)2.03590384
119Hypertriglyceridemia (HP:0002155)2.02788293
120Hypoproteinemia (HP:0003075)2.02358141
121Joint stiffness (HP:0001387)2.00226172
122Verrucae (HP:0200043)1.99973592
123Papilloma (HP:0012740)1.99973592
124Aplasia/Hypoplasia of the sacrum (HP:0008517)1.99663727
125Easy fatigability (HP:0003388)1.99484730
126Autoimmune hemolytic anemia (HP:0001890)1.97103938
127Abnormality of the heme biosynthetic pathway (HP:0010472)1.95589103
128Skin ulcer (HP:0200042)1.95047689
129Increased cerebral lipofuscin (HP:0011813)1.94875724
130Hypergammaglobulinemia (HP:0010702)1.94677224
131Recurrent lower respiratory tract infections (HP:0002783)1.93707948
132Amaurosis fugax (HP:0100576)1.93222830
133Prostate neoplasm (HP:0100787)1.93181381
134Chromsome breakage (HP:0040012)1.92444305
135Cheilitis (HP:0100825)1.92200660
136Restrictive lung disease (HP:0002091)1.92116095
137Chronic sinusitis (HP:0011109)1.91815552
138Sepsis (HP:0100806)1.91123391
139Purpura (HP:0000979)1.89207946
140Polygenic inheritance (HP:0010982)1.84932596
141Asymmetric septal hypertrophy (HP:0001670)1.84820601
142Emphysema (HP:0002097)1.83732509
143Abnormal hair laboratory examination (HP:0003328)1.82498402
144Neuronal loss in central nervous system (HP:0002529)1.78628855
145Abnormality of the distal phalanges of the toes (HP:0010182)1.78479806
146Myopathic facies (HP:0002058)1.78294710
147Seborrheic dermatitis (HP:0001051)1.77832761
148Systemic lupus erythematosus (HP:0002725)1.73700783
149Arterial thrombosis (HP:0004420)1.72915943
150Skin rash (HP:0000988)1.72693040
151Metaphyseal cupping (HP:0003021)1.72653827
152Premature loss of primary teeth (HP:0006323)1.72454814

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.19028870
2MAP4K13.80511397
3KIT2.81677500
4IKBKE2.81029384
5TBK12.79442246
6SIK12.74495283
7TYK22.65038700
8TXK2.47227402
9EPHA22.40957722
10ZAP702.37094048
11MAP3K142.35186927
12TESK22.28224780
13FLT32.21817566
14TEC2.20699760
15IRAK42.19325612
16SMG12.14477138
17JAK32.10359414
18EEF2K2.09949662
19TGFBR22.02887662
20PRPF4B2.02877875
21NME21.99423562
22IKBKB1.95985843
23TGFBR11.93805004
24BTK1.93723856
25PIM21.88658180
26BLK1.82139655
27MAP2K31.78403329
28EPHB11.74924558
29TAOK11.73046591
30STK161.70967473
31TAOK31.64956562
32MST1R1.64573240
33MAP3K121.59074836
34MAP3K131.55234814
35RPS6KA41.54372275
36SYK1.53571360
37ACVR1B1.52574924
38ERN11.44403930
39SIK31.38473780
40CSF1R1.37496356
41TESK11.35470116
42STK101.31975009
43PTK61.29876040
44KDR1.29640742
45ICK1.29377148
46NLK1.28462695
47RIPK41.23386280
48ITK1.22238283
49JAK11.21456720
50RPS6KB21.21192826
51LRRK21.20513585
52PIM11.18151826
53LCK1.14868449
54RIPK11.13792363
55IRAK31.13639712
56CHUK1.13578898
57TNIK1.12932267
58MUSK1.09858701
59MARK21.08440605
60MAPK151.08402458
61MAPKAPK31.07456931
62MATK1.06508199
63LYN1.05200448
64CDK121.04599375
65RAF11.02848699
66MST41.02678940
67TIE11.02161875
68FGFR41.01701207
69TAOK21.01489974
70VRK11.01081566
71WEE11.00464657
72PDPK11.00253588
73MAP2K20.99614437
74MAP3K60.99289976
75PIK3CG0.88614015
76CDK80.88440899
77IRAK20.83621209
78HCK0.83614607
79HIPK20.81696024
80MAP2K60.79518563
81SIK20.78928809
82RPS6KA20.77752385
83RPS6KC10.74886860
84RPS6KL10.74886860
85MAP3K110.73676683
86DYRK30.73001531
87FGFR30.72191902
88TRPM70.72054388
89MAPKAPK50.71736538
90GRK60.70427073
91CDC42BPA0.70411258
92PAK40.69947392
93PDK10.69847039
94ADRBK20.68445924
95PASK0.67718174
96SCYL20.67650472
97MAPK110.63928678
98EIF2AK30.63586039
99ATR0.61902705
100CSK0.61001984
101CDK70.60747340
102CLK10.60461413
103BMX0.60072513
104PLK40.58689409
105MAPK120.58394795
106JAK20.56705186
107NEK20.56585716
108NEK90.55788089
109FES0.55584186
110BUB10.54732366
111MTOR0.54074063
112MKNK10.53178582
113MAP3K70.52998861
114PRKG20.52256439
115FGR0.51698066
116PRKCI0.50533538
117RET0.48632057
118MARK30.48286445
119IRAK10.47448454
120MAPK70.47143902
121MAP3K100.45533312
122KSR20.45483193
123DYRK1B0.44376331
124PRKD10.44294503
125MAP3K30.43761293
126MAP3K80.43117698
127PRKD20.42741383
128AURKB0.42631198
129YES10.42020676
130STK40.41167176
131RPS6KA60.40403158
132CAMKK10.40202350
133BMPR1B0.40182068
134MYLK0.40117645
135BRSK20.38917281
136MAPKAPK20.38892340
137EIF2AK20.38824328
138CDK40.38398124
139TNK20.38148106
140PRKD30.38043821
141SRPK10.37959175
142STK380.36894292
143PKN20.34370628
144STK240.33776445
145ARAF0.33572934
146CAMKK20.33531382
147MAP3K10.32209174

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.02041064
2Ribosome_Homo sapiens_hsa030102.83758748
3DNA replication_Homo sapiens_hsa030302.77921690
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.77791151
5Leishmaniasis_Homo sapiens_hsa051402.35855761
6RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.15318292
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.12144664
8Measles_Homo sapiens_hsa051622.11875754
9Base excision repair_Homo sapiens_hsa034102.11376555
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.97118511
11Homologous recombination_Homo sapiens_hsa034401.95593560
12Antigen processing and presentation_Homo sapiens_hsa046121.93928238
13Mismatch repair_Homo sapiens_hsa034301.91626548
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.87942453
15Herpes simplex infection_Homo sapiens_hsa051681.83731659
16Hematopoietic cell lineage_Homo sapiens_hsa046401.78546540
17B cell receptor signaling pathway_Homo sapiens_hsa046621.77470053
18Toll-like receptor signaling pathway_Homo sapiens_hsa046201.75432432
19NOD-like receptor signaling pathway_Homo sapiens_hsa046211.64996978
20Osteoclast differentiation_Homo sapiens_hsa043801.63990975
21Non-homologous end-joining_Homo sapiens_hsa034501.62555778
22Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.58426409
23Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.57675539
24Allograft rejection_Homo sapiens_hsa053301.56141562
25Other glycan degradation_Homo sapiens_hsa005111.54114872
26Influenza A_Homo sapiens_hsa051641.53354938
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.51876374
28Notch signaling pathway_Homo sapiens_hsa043301.48284603
29Fructose and mannose metabolism_Homo sapiens_hsa000511.45552319
30Legionellosis_Homo sapiens_hsa051341.43539447
31Pertussis_Homo sapiens_hsa051331.37940016
32Shigellosis_Homo sapiens_hsa051311.36327765
33Pyrimidine metabolism_Homo sapiens_hsa002401.32500389
34T cell receptor signaling pathway_Homo sapiens_hsa046601.27904190
35Proteasome_Homo sapiens_hsa030501.27296721
36Toxoplasmosis_Homo sapiens_hsa051451.26554348
37Apoptosis_Homo sapiens_hsa042101.26460781
38Acute myeloid leukemia_Homo sapiens_hsa052211.25246048
39RNA polymerase_Homo sapiens_hsa030201.24371075
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.24246068
41Cyanoamino acid metabolism_Homo sapiens_hsa004601.21987622
42Graft-versus-host disease_Homo sapiens_hsa053321.19670479
43TNF signaling pathway_Homo sapiens_hsa046681.15856354
44Nucleotide excision repair_Homo sapiens_hsa034201.13666270
45Hepatitis B_Homo sapiens_hsa051611.11965586
46Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.09316820
47RNA degradation_Homo sapiens_hsa030181.09179167
48Spliceosome_Homo sapiens_hsa030401.08425126
49Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.07083096
50p53 signaling pathway_Homo sapiens_hsa041151.05865375
51Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.05512977
52Endocytosis_Homo sapiens_hsa041441.04419766
53Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02517985
54Tuberculosis_Homo sapiens_hsa051521.00757360
55Epstein-Barr virus infection_Homo sapiens_hsa051691.00298093
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.99836777
57Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.99407639
58Fanconi anemia pathway_Homo sapiens_hsa034600.98278026
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.96066149
60Bladder cancer_Homo sapiens_hsa052190.95249875
61Hepatitis C_Homo sapiens_hsa051600.94724589
62Leukocyte transendothelial migration_Homo sapiens_hsa046700.94474159
63Malaria_Homo sapiens_hsa051440.91747550
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91514763
65Platelet activation_Homo sapiens_hsa046110.90808479
66Sulfur relay system_Homo sapiens_hsa041220.89882096
67Insulin resistance_Homo sapiens_hsa049310.89317875
68Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.88028148
69Galactose metabolism_Homo sapiens_hsa000520.86355748
70Glycerophospholipid metabolism_Homo sapiens_hsa005640.86262275
71mTOR signaling pathway_Homo sapiens_hsa041500.85710511
72Cell cycle_Homo sapiens_hsa041100.85630358
73Endometrial cancer_Homo sapiens_hsa052130.84103768
74Protein export_Homo sapiens_hsa030600.83748331
75Phagosome_Homo sapiens_hsa041450.83259958
76Chronic myeloid leukemia_Homo sapiens_hsa052200.83110629
77N-Glycan biosynthesis_Homo sapiens_hsa005100.81459137
78Salmonella infection_Homo sapiens_hsa051320.80895861
79Folate biosynthesis_Homo sapiens_hsa007900.80113907
80Basal transcription factors_Homo sapiens_hsa030220.79879249
81Prolactin signaling pathway_Homo sapiens_hsa049170.79052107
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.78231265
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78218329
84Chemokine signaling pathway_Homo sapiens_hsa040620.77695982
85Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.76746570
86Pancreatic cancer_Homo sapiens_hsa052120.72849396
87Choline metabolism in cancer_Homo sapiens_hsa052310.72495427
88Autoimmune thyroid disease_Homo sapiens_hsa053200.71177796
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70297274
90Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70167459
91Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.69896789
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.69568714
93Phosphatidylinositol signaling system_Homo sapiens_hsa040700.67890011
94Insulin signaling pathway_Homo sapiens_hsa049100.67043534
95Thyroid cancer_Homo sapiens_hsa052160.66157147
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.65872156
97Small cell lung cancer_Homo sapiens_hsa052220.64772147
98AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64549555
99Lysosome_Homo sapiens_hsa041420.64311277
100Inositol phosphate metabolism_Homo sapiens_hsa005620.64167011
101Asthma_Homo sapiens_hsa053100.63458326
102RNA transport_Homo sapiens_hsa030130.63278030
103Viral carcinogenesis_Homo sapiens_hsa052030.63060487
104GnRH signaling pathway_Homo sapiens_hsa049120.62667779
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.62358692
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62142607
107Purine metabolism_Homo sapiens_hsa002300.61403268
108Amoebiasis_Homo sapiens_hsa051460.61304338
109Renal cell carcinoma_Homo sapiens_hsa052110.60053104
110ErbB signaling pathway_Homo sapiens_hsa040120.57861818
111Central carbon metabolism in cancer_Homo sapiens_hsa052300.57607275
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56902183
113HTLV-I infection_Homo sapiens_hsa051660.56545007
114Viral myocarditis_Homo sapiens_hsa054160.56172079
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52928840
116Rheumatoid arthritis_Homo sapiens_hsa053230.52586125
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.52165404
118Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51035736
119Sphingolipid metabolism_Homo sapiens_hsa006000.50088274
120Type I diabetes mellitus_Homo sapiens_hsa049400.48644916
121Staphylococcus aureus infection_Homo sapiens_hsa051500.48158833
122Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47175390
123Pentose phosphate pathway_Homo sapiens_hsa000300.46570530
124African trypanosomiasis_Homo sapiens_hsa051430.46193513
125Phenylalanine metabolism_Homo sapiens_hsa003600.46028870
126Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45954819
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.44884602
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.43652118
129Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42653612
130Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.42644829
131Non-small cell lung cancer_Homo sapiens_hsa052230.39433724
132Arachidonic acid metabolism_Homo sapiens_hsa005900.38335229
133Estrogen signaling pathway_Homo sapiens_hsa049150.38074168
134Caffeine metabolism_Homo sapiens_hsa002320.37759801
135Colorectal cancer_Homo sapiens_hsa052100.35902170
136VEGF signaling pathway_Homo sapiens_hsa043700.34873110

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