ARHGAP10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)5.20695827
2positive regulation by symbiont of host defense response (GO:0052509)4.49485760
3modulation by symbiont of host defense response (GO:0052031)4.49485760
4modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.49485760
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.49485760
6positive regulation by organism of defense response of other organism involved in symbiotic interact4.49485760
7modulation by symbiont of host immune response (GO:0052553)4.49485760
8regulation of vitamin D biosynthetic process (GO:0060556)4.23478449
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.14579452
10cardiac myofibril assembly (GO:0055003)4.02744226
11sarcomere organization (GO:0045214)3.94942058
12cell adhesion mediated by integrin (GO:0033627)3.91687430
13wound healing, spreading of epidermal cells (GO:0035313)3.91329189
14myofibril assembly (GO:0030239)3.72501229
15muscle filament sliding (GO:0030049)3.60851087
16actin-myosin filament sliding (GO:0033275)3.60851087
17sarcoplasmic reticulum calcium ion transport (GO:0070296)3.54758552
18apoptotic cell clearance (GO:0043277)3.54156827
19cellular response to thyroid hormone stimulus (GO:0097067)3.49909012
20negative regulation of nitric oxide biosynthetic process (GO:0045019)3.47579164
21regulation of interferon-beta biosynthetic process (GO:0045357)3.37365365
22negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.37198083
23regulation of integrin activation (GO:0033623)3.36626499
24regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.34806289
25regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.28736648
26virion attachment to host cell (GO:0019062)3.21998696
27adhesion of symbiont to host cell (GO:0044650)3.21998696
28positive regulation of interferon-alpha production (GO:0032727)3.20089103
29regulation of T-helper 1 cell differentiation (GO:0045625)3.18589067
30regulation of vitamin metabolic process (GO:0030656)3.15611853
31negative regulation of interleukin-12 production (GO:0032695)3.14316633
32barbed-end actin filament capping (GO:0051016)3.10746307
33natural killer cell mediated cytotoxicity (GO:0042267)3.08621157
34natural killer cell mediated immunity (GO:0002228)3.08621157
35positive regulation of p38MAPK cascade (GO:1900745)3.08047860
36fibroblast migration (GO:0010761)3.06470916
37cellular response to interferon-alpha (GO:0035457)3.05127651
38regulation of interferon-alpha production (GO:0032647)3.04730417
39actin-mediated cell contraction (GO:0070252)3.02507052
40endodermal cell differentiation (GO:0035987)3.02061420
41regulation of skeletal muscle contraction (GO:0014819)3.01922515
42glycosphingolipid catabolic process (GO:0046479)2.99404854
43positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.99079611
44NLS-bearing protein import into nucleus (GO:0006607)2.98583217
45positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.95972763
46macrophage activation involved in immune response (GO:0002281)2.93268932
47pinocytosis (GO:0006907)2.91694379
48response to host (GO:0075136)2.91446309
49response to host defenses (GO:0052200)2.91446309
50response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.91446309
51axon extension involved in axon guidance (GO:0048846)2.88670089
52neuron projection extension involved in neuron projection guidance (GO:1902284)2.88670089
53oligosaccharide catabolic process (GO:0009313)2.87671838
54regulation of cholesterol storage (GO:0010885)2.87339260
55wound healing, spreading of cells (GO:0044319)2.86565553
56response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.86414206
57response to host immune response (GO:0052572)2.86414206
58actomyosin structure organization (GO:0031032)2.85423841
59low-density lipoprotein particle clearance (GO:0034383)2.85400004
60positive regulation of natural killer cell activation (GO:0032816)2.84536395
61positive regulation of chemokine biosynthetic process (GO:0045080)2.83177649
62adhesion of symbiont to host (GO:0044406)2.81073343
63positive regulation of gamma-delta T cell activation (GO:0046645)2.78944466
64actin filament-based movement (GO:0030048)2.78932337
65negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.78154000
66skeletal muscle adaptation (GO:0043501)2.76721594
67cell-substrate junction assembly (GO:0007044)2.76298730
68positive regulation of heat generation (GO:0031652)2.74005565
69positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.72984426
70cardiac muscle cell development (GO:0055013)2.72748874
71vascular endothelial growth factor signaling pathway (GO:0038084)2.72473767
72T-helper 1 type immune response (GO:0042088)2.71423501
73germinal center formation (GO:0002467)2.70773079
74substrate-dependent cell migration (GO:0006929)2.69083690
75lipopolysaccharide-mediated signaling pathway (GO:0031663)2.68439094
76striated muscle atrophy (GO:0014891)2.68222822
77regulation of tight junction assembly (GO:2000810)2.66763159
78response to thyroid hormone (GO:0097066)2.66120116
79negative regulation of potassium ion transmembrane transport (GO:1901380)2.65573423
80myeloid dendritic cell differentiation (GO:0043011)2.65190458
81intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631)2.64709619
82glycolipid catabolic process (GO:0019377)2.63919446
83regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.63782601
84cardiac cell development (GO:0055006)2.63731781
85negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.61609363
86response to muramyl dipeptide (GO:0032495)2.60990394
87hypotonic response (GO:0006971)2.60949366
88response to inactivity (GO:0014854)2.59549469
89regulation of cytokine secretion involved in immune response (GO:0002739)2.58827878
90regulation of membrane protein ectodomain proteolysis (GO:0051043)2.57306184
91I-kappaB phosphorylation (GO:0007252)2.56889760
92positive regulation of natural killer cell differentiation (GO:0032825)2.56019903
93cellular response to arsenic-containing substance (GO:0071243)2.56009867
94stress fiber assembly (GO:0043149)2.55873355
95regulation of chronic inflammatory response (GO:0002676)2.55677795
96basement membrane organization (GO:0071711)2.54550910
97positive regulation of endothelial cell apoptotic process (GO:2000353)2.53541595
98epithelial cell-cell adhesion (GO:0090136)2.53407684
99protein localization to endosome (GO:0036010)2.53138379
100keratan sulfate catabolic process (GO:0042340)2.52620173
101positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.51866751
102regulation of p38MAPK cascade (GO:1900744)2.51774742
103protein hydroxylation (GO:0018126)2.50691624
104positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.50535235
105response to interferon-alpha (GO:0035455)2.50015296
106negative regulation of fatty acid transport (GO:2000192)2.49781384
107regulation of interleukin-12 biosynthetic process (GO:0045075)2.47326620
108regulation of fever generation (GO:0031620)2.46641096
109regulation of mononuclear cell migration (GO:0071675)2.46105193
110regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.46098832
111regulation of chemokine biosynthetic process (GO:0045073)2.44163861
112skin morphogenesis (GO:0043589)2.42895168
113neutrophil activation involved in immune response (GO:0002283)2.42891648
114positive regulation of T-helper cell differentiation (GO:0045624)2.41798551
115positive regulation of interferon-beta production (GO:0032728)2.41257450
116regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510)2.40597185
117positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.39120594
118regulation of macrophage cytokine production (GO:0010935)2.39046707
119positive regulation of interleukin-17 production (GO:0032740)2.38628001
120positive regulation of monocyte chemotaxis (GO:0090026)2.37862493
121modulation by symbiont of host cellular process (GO:0044068)2.37223252
122negative regulation of homotypic cell-cell adhesion (GO:0034111)2.36441300
123regulation of SMAD protein import into nucleus (GO:0060390)2.35812454
124regulation of podosome assembly (GO:0071801)2.35372095
125positive regulation of lipid storage (GO:0010884)2.35332232
126apoptotic process involved in morphogenesis (GO:0060561)2.35002257
127negative regulation of cell size (GO:0045792)2.34629906
128skeletal muscle contraction (GO:0003009)2.34578503
129regulation of sequestering of triglyceride (GO:0010889)2.33595562
130retina vasculature morphogenesis in camera-type eye (GO:0061299)2.33250857
131positive regulation of SMAD protein import into nucleus (GO:0060391)2.33100282
132immunoglobulin mediated immune response (GO:0016064)2.32538254
133nuclear pore complex assembly (GO:0051292)2.32286834
134cortical actin cytoskeleton organization (GO:0030866)2.32161831
135negative regulation of monooxygenase activity (GO:0032769)2.31192266
136regulation of natural killer cell activation (GO:0032814)2.30706654
137collagen fibril organization (GO:0030199)2.30507799
138cytoplasmic mRNA processing body assembly (GO:0033962)2.29992333
139T cell apoptotic process (GO:0070231)2.26728579
140positive regulation of smooth muscle cell migration (GO:0014911)2.26707311
141regulation of nitric oxide biosynthetic process (GO:0045428)2.26448777
142cell migration involved in heart development (GO:0060973)2.25251456
143decidualization (GO:0046697)2.25233105
144regulation of macrophage derived foam cell differentiation (GO:0010743)2.23960168
145cardiac muscle contraction (GO:0060048)2.23354186
146focal adhesion assembly (GO:0048041)2.23123110
147cell-substrate adherens junction assembly (GO:0007045)2.23123110
148regulation of macrophage chemotaxis (GO:0010758)2.22845041
149ceramide catabolic process (GO:0046514)2.22840556
150regulation of integrin-mediated signaling pathway (GO:2001044)2.22478878
151negative regulation of lipid storage (GO:0010888)2.22003934
152positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.21958381
153regulation of early endosome to late endosome transport (GO:2000641)2.21305484
154regulation of interleukin-12 production (GO:0032655)2.20905835
155regulation of mitotic spindle organization (GO:0060236)2.20824117
156membrane raft organization (GO:0031579)2.20466727
157hemidesmosome assembly (GO:0031581)2.20288812
158response to peptidoglycan (GO:0032494)2.20087290
159regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.19215821
160regulation of immunoglobulin secretion (GO:0051023)2.18869735
161regulation of T-helper cell differentiation (GO:0045622)2.18718981
162positive regulation of bone resorption (GO:0045780)2.17768298
163positive regulation of defense response to virus by host (GO:0002230)2.17178815
164muscle atrophy (GO:0014889)2.16747597
165monocyte chemotaxis (GO:0002548)2.16165438
166cellular response to lipopolysaccharide (GO:0071222)2.15788585

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.32113356
2EGR1_19374776_ChIP-ChIP_THP-1_Human3.54069242
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.24882998
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.19438104
5E2F7_22180533_ChIP-Seq_HELA_Human3.08133784
6TP63_17297297_ChIP-ChIP_HaCaT_Human2.96883076
7SMAD_19615063_ChIP-ChIP_OVARY_Human2.92288489
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.86855848
9RARG_19884340_ChIP-ChIP_MEFs_Mouse2.83404756
10Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.53776718
11SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.46116973
12NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.41724015
13MYB_21317192_ChIP-Seq_ERMYB_Mouse2.33997719
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.32586830
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.31234746
16STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.27864464
17GATA1_22025678_ChIP-Seq_K562_Human2.22734930
18TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.07414163
19ELK3_25401928_ChIP-Seq_HUVEC_Human2.05886553
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.98972171
21* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.95324844
22HIF1A_21447827_ChIP-Seq_MCF-7_Human1.94561831
23BRD4_27068464_Chip-Seq_AML-cells_Mouse1.93585775
24ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.88159702
25MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.81640369
26TRIM28_21343339_ChIP-Seq_HEK293_Human1.79811203
27MYC_22102868_ChIP-Seq_BL_Human1.78831852
28KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.78666058
29ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.77182383
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.76977869
31CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.76738202
32VDR_21846776_ChIP-Seq_THP-1_Human1.76430607
33* SPI1_23127762_ChIP-Seq_K562_Human1.75536953
34CLOCK_20551151_ChIP-Seq_293T_Human1.75279526
35TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73475870
36TCF7_22412390_ChIP-Seq_EML_Mouse1.72523788
37KDM2B_26808549_Chip-Seq_DND41_Human1.68336231
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.68041730
39KDM2B_26808549_Chip-Seq_SUP-B15_Human1.66672073
40RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.65106843
41ATF3_27146783_Chip-Seq_COLON_Human1.63361601
42TBX20_22328084_ChIP-Seq_HEART_Mouse1.62275135
43TBX20_22080862_ChIP-Seq_HEART_Mouse1.62275135
44AR_21909140_ChIP-Seq_LNCAP_Human1.60140645
45KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.56569417
46MAF_26560356_Chip-Seq_TH1_Human1.56228623
47GATA2_21666600_ChIP-Seq_HMVEC_Human1.51078847
48SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.50896008
49SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.50896008
50ESR1_21235772_ChIP-Seq_MCF-7_Human1.50419461
51FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.50088456
52NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.48004212
53SOX9_24532713_ChIP-Seq_HFSC_Mouse1.47437328
54PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.45607178
55* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.45216732
56FOXO3_23340844_ChIP-Seq_DLD1_Human1.44530533
57TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.44218178
58NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.43239814
59TFEB_21752829_ChIP-Seq_HELA_Human1.42085119
60BRD4_25478319_ChIP-Seq_HGPS_Human1.41771862
61PPAR_26484153_Chip-Seq_NCI-H1993_Human1.40514969
62P300_27058665_Chip-Seq_ZR-75-30cells_Human1.37220102
63NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.36776997
64NRF2_20460467_ChIP-Seq_MEFs_Mouse1.36776997
65EP300_21415370_ChIP-Seq_HL-1_Mouse1.35758639
66TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.35501801
67VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.35403630
68KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.35397702
69UTX_26944678_Chip-Seq_JUKART_Human1.34666018
70STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.33872809
71* VDR_24763502_ChIP-Seq_THP-1_Human1.33690674
72IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.32844675
73UBF1/2_26484160_Chip-Seq_HMECs_Human1.32512599
74SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.31876129
75BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.31390904
76SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.29028816
77STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.28525018
78TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.28238283
79PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.26818696
80FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.24806365
81ESR2_21235772_ChIP-Seq_MCF-7_Human1.24186893
82RUNX1_22412390_ChIP-Seq_EML_Mouse1.23995192
83NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.23466594
84NFIB_24661679_ChIP-Seq_LUNG_Mouse1.22558172
85RUNX_20019798_ChIP-Seq_JUKART_Human1.21849542
86SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21257247
87PU_27001747_Chip-Seq_BMDM_Mouse1.20973082
88* RACK7_27058665_Chip-Seq_MCF-7_Human1.19667092
89KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.19312629
90PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.15855530
91CJUN_26792858_Chip-Seq_BT549_Human1.15201088
92LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.15050652
93GATA1_19941827_ChIP-Seq_MEL_Mouse1.14527342
94ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.14480598
95* MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.14362760
96SPI1_23547873_ChIP-Seq_NB4_Human1.14094018
97ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.14034251
98CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.14024997
99ESR1_20079471_ChIP-ChIP_T-47D_Human1.12781578
100PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.12134040
101VDR_24787735_ChIP-Seq_THP-1_Human1.12125041
102TP53_16413492_ChIP-PET_HCT116_Human1.11494732
103FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.10251635
104NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09673553
105PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09547998
106JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07210303
107STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.07036391
108MYB_26560356_Chip-Seq_TH1_Human1.06991669
109RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.06609661
110GATA4_21415370_ChIP-Seq_HL-1_Mouse1.05376075
111MYB_26560356_Chip-Seq_TH2_Human1.04757218
112NCOR1_26117541_ChIP-Seq_K562_Human1.04027564
113CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03275106
114E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.02093445
115TP53_22127205_ChIP-Seq_IMR90_Human1.01540092
116STAT4_19710469_ChIP-ChIP_TH1__Mouse1.00887234
117FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.00061188
118JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99750445
119TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.98655571
120PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.97335418
121FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.96818836
122KDM2B_26808549_Chip-Seq_JURKAT_Human0.96555544
123GATA6_25053715_ChIP-Seq_YYC3_Human0.95360405
124STAT3_1855785_ChIP-Seq_MESCs_Mouse0.94502098
125GATA1_19941827_ChIP-Seq_MEL86_Mouse0.94326719
126SCL_19346495_ChIP-Seq_HPC-7_Human0.93516206
127SALL4_18804426_ChIP-ChIP_XEN_Mouse0.93370509
128GATA1_19941826_ChIP-Seq_K562_Human0.93043348
129E2F1_21310950_ChIP-Seq_MCF-7_Human0.92143371
130SMC1_22415368_ChIP-Seq_MEFs_Mouse0.92055712
131LXR_22158963_ChIP-Seq_LIVER_Mouse0.91340466
132AHR_22903824_ChIP-Seq_MCF-7_Human0.87616595

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.79546614
2MP0003705_abnormal_hypodermis_morpholog3.32304701
3MP0000569_abnormal_digit_pigmentation3.19683328
4MP0004084_abnormal_cardiac_muscle2.78982139
5MP0003646_muscle_fatigue2.63805393
6MP0003566_abnormal_cell_adhesion2.56596667
7MP0000751_myopathy2.45034566
8MP0005058_abnormal_lysosome_morphology2.43519422
9MP0005275_abnormal_skin_tensile2.26843102
10MP0001958_emphysema2.21980632
11MP0000750_abnormal_muscle_regeneration2.20803573
12MP0004510_myositis2.13677626
13MP0005451_abnormal_body_composition2.12780274
14MP0000749_muscle_degeneration2.12073233
15MP0003303_peritoneal_inflammation2.02708976
16MP0010307_abnormal_tumor_latency1.98767122
17MP0002148_abnormal_hypersensitivity_rea1.97337877
18MP0005076_abnormal_cell_differentiation1.92133443
19MP0010352_gastrointestinal_tract_polyps1.87537385
20MP0000733_abnormal_muscle_development1.87013050
21MP0002837_dystrophic_cardiac_calcinosis1.86459829
22MP0004087_abnormal_muscle_fiber1.84692689
23MP0003279_aneurysm1.80630983
24MP0003191_abnormal_cellular_cholesterol1.77323014
25MP0008004_abnormal_stomach_pH1.75363389
26MP0004036_abnormal_muscle_relaxation1.74593324
27MP0009278_abnormal_bone_marrow1.74069185
28MP0003300_gastrointestinal_ulcer1.67388129
29MP0003724_increased_susceptibility_to1.62423171
30MP0010630_abnormal_cardiac_muscle1.60589098
31MP0003828_pulmonary_edema1.55136482
32MP0005330_cardiomyopathy1.53732653
33MP0005257_abnormal_intraocular_pressure1.51269731
34MP0002106_abnormal_muscle_physiology1.50438831
35MP0008775_abnormal_heart_ventricle1.50087105
36MP0005023_abnormal_wound_healing1.50012919
37MP0004130_abnormal_muscle_cell1.49975539
38MP0003091_abnormal_cell_migration1.47130857
39MP0004233_abnormal_muscle_weight1.45063416
40MP0001790_abnormal_immune_system1.44745239
41MP0005387_immune_system_phenotype1.44745239
42MP0009785_altered_susceptibility_to1.44477059
43MP0005623_abnormal_meninges_morphology1.44021828
44MP0003448_altered_tumor_morphology1.43772100
45MP0003950_abnormal_plasma_membrane1.37503769
46MP0002269_muscular_atrophy1.37325801
47MP0003172_abnormal_lysosome_physiology1.36432428
48MP0005503_abnormal_tendon_morphology1.34192341
49MP0000343_altered_response_to1.34146723
50MP0001542_abnormal_bone_strength1.33436537
51MP0004215_abnormal_myocardial_fiber1.32869868
52MP0004947_skin_inflammation1.29701140
53MP0010368_abnormal_lymphatic_system1.29533396
54MP0004272_abnormal_basement_membrane1.29447291
55MP0002972_abnormal_cardiac_muscle1.27981308
56MP0000759_abnormal_skeletal_muscle1.27378368
57MP0000747_muscle_weakness1.26360543
58MP0001544_abnormal_cardiovascular_syste1.26313613
59MP0005385_cardiovascular_system_phenoty1.26313613
60MP0004185_abnormal_adipocyte_glucose1.22593750
61MP0005165_increased_susceptibility_to1.21584954
62MP0003221_abnormal_cardiomyocyte_apopto1.20981146
63MP0000767_abnormal_smooth_muscle1.20268552
64MP0003075_altered_response_to1.19734006
65MP0005369_muscle_phenotype1.19176910
66MP0006054_spinal_hemorrhage1.18489145
67MP0003436_decreased_susceptibility_to1.18252738
68MP0005671_abnormal_response_to1.16740250
69MP0001545_abnormal_hematopoietic_system1.12365136
70MP0005397_hematopoietic_system_phenotyp1.12365136
71MP0009764_decreased_sensitivity_to1.11377473
72MP0001853_heart_inflammation1.10929890
73MP0005025_abnormal_response_to1.09557674
74MP0005620_abnormal_muscle_contractility1.08230878
75MP0004808_abnormal_hematopoietic_stem1.05939483
76MP0000858_altered_metastatic_potential1.05486641
77MP0002998_abnormal_bone_remodeling1.03083493
78MP0002723_abnormal_immune_serum1.02914325
79MP0003567_abnormal_fetal_cardiomyocyte1.01926663
80MP0005595_abnormal_vascular_smooth1.01919854
81MP0002254_reproductive_system_inflammat1.01772959
82MP0001835_abnormal_antigen_presentation1.01278991
83MP0002877_abnormal_melanocyte_morpholog1.00545327
84MP0002419_abnormal_innate_immunity1.00228571
85MP0003045_fibrosis1.00163032
86MP0005164_abnormal_response_to0.99898352
87MP0006082_CNS_inflammation0.99230900
88MP0005167_abnormal_blood-brain_barrier0.98780283
89MP0001533_abnormal_skeleton_physiology0.95609961
90MP0002060_abnormal_skin_morphology0.94689465
91MP0004484_altered_response_of0.94473541
92MP0000604_amyloidosis0.91347376
93MP0005310_abnormal_salivary_gland0.90790943
94MP0005666_abnormal_adipose_tissue0.90524737
95MP0001915_intracranial_hemorrhage0.90363416
96MP0005670_abnormal_white_adipose0.89579132
97MP0002405_respiratory_system_inflammati0.89138696
98MP0000266_abnormal_heart_morphology0.88561940
99MP0001845_abnormal_inflammatory_respons0.88010381
100MP0001800_abnormal_humoral_immune0.87483678
101MP0002332_abnormal_exercise_endurance0.85693657
102MP0005166_decreased_susceptibility_to0.84619113
103MP0010155_abnormal_intestine_physiology0.84584104
104MP0006138_congestive_heart_failure0.84383788
105MP0002896_abnormal_bone_mineralization0.84177025
106MP0000249_abnormal_blood_vessel0.83307955
107MP0000685_abnormal_immune_system0.83076112
108MP0008469_abnormal_protein_level0.82935787
109MP0003984_embryonic_growth_retardation0.82047619
110MP0002088_abnormal_embryonic_growth/wei0.81837864
111MP0004145_abnormal_muscle_electrophysio0.81778073
112MP0002166_altered_tumor_susceptibility0.81030344
113MP0002971_abnormal_brown_adipose0.80674344
114MP0002128_abnormal_blood_circulation0.80419614
115MP0002452_abnormal_antigen_presenting0.79355860
116MP0002396_abnormal_hematopoietic_system0.78944254
117MP0003453_abnormal_keratinocyte_physiol0.77402978
118MP0002925_abnormal_cardiovascular_devel0.75954582
119MP0001243_abnormal_dermal_layer0.75014516
120MP0005375_adipose_tissue_phenotype0.74632781
121MP0009840_abnormal_foam_cell0.74497113
122MP0000371_diluted_coat_color0.73691424
123MP0005464_abnormal_platelet_physiology0.73509858
124MP0001614_abnormal_blood_vessel0.73277760
125MP0002086_abnormal_extraembryonic_tissu0.71326466
126MP0005621_abnormal_cell_physiology0.69728621
127MP0002006_tumorigenesis0.69397324
128MP0005000_abnormal_immune_tolerance0.68195370
129MP0005390_skeleton_phenotype0.67890289
130MP0002108_abnormal_muscle_morphology0.67711596
131MP0001672_abnormal_embryogenesis/_devel0.67672108
132MP0005380_embryogenesis_phenotype0.67672108
133MP0002933_joint_inflammation0.67633493

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)5.08125595
2Abnormality of liposaccharide metabolism (HP:0010968)5.08125595
3Abnormality of glycosphingolipid metabolism (HP:0004343)5.08125595
4Increased connective tissue (HP:0009025)4.56911422
5Muscle fiber splitting (HP:0003555)4.05840673
6Exercise-induced muscle cramps (HP:0003710)4.05272417
7Premature rupture of membranes (HP:0001788)3.93388200
8Protrusio acetabuli (HP:0003179)3.79923887
9Ankle contracture (HP:0006466)3.64103551
10Type 1 muscle fiber predominance (HP:0003803)3.56545849
11Cerebral aneurysm (HP:0004944)3.53092086
12Dysostosis multiplex (HP:0000943)3.40950150
13Hyporeflexia of lower limbs (HP:0002600)3.40048827
14Difficulty climbing stairs (HP:0003551)3.27535545
15Asymmetric septal hypertrophy (HP:0001670)3.18751598
16Sudden death (HP:0001699)3.11871396
17Ventricular tachycardia (HP:0004756)3.00624120
18Distal lower limb amyotrophy (HP:0008944)2.99185994
19Increased cerebral lipofuscin (HP:0011813)2.99077249
20Loss of speech (HP:0002371)2.98945075
21Aortic aneurysm (HP:0004942)2.90938237
22Right ventricular cardiomyopathy (HP:0011663)2.75574382
23Cervical subluxation (HP:0003308)2.74937644
24Frequent falls (HP:0002359)2.74819950
25Difficulty running (HP:0009046)2.74636151
26Subaortic stenosis (HP:0001682)2.72777518
27Abnormality of the left ventricular outflow tract (HP:0011103)2.72777518
28Recurrent abscess formation (HP:0002722)2.69990852
29Aortic dissection (HP:0002647)2.67206670
30Hematochezia (HP:0002573)2.66012042
31Shallow orbits (HP:0000586)2.65392782
32Lipoatrophy (HP:0100578)2.63733780
33Abnormality of the calf musculature (HP:0001430)2.63390142
34Osteolytic defects of the hand bones (HP:0009699)2.59346227
35Osteolytic defects of the phalanges of the hand (HP:0009771)2.59346227
36Scapular winging (HP:0003691)2.52446625
37EMG: myopathic abnormalities (HP:0003458)2.51154803
38Abnormality of polysaccharide metabolism (HP:0011012)2.47223982
39Abnormality of glycosaminoglycan metabolism (HP:0004371)2.47223982
40Abnormality of mucopolysaccharide metabolism (HP:0011020)2.47223982
41Dilatation of the ascending aorta (HP:0005111)2.45787628
42Exercise-induced myalgia (HP:0003738)2.45746335
43Increased density of long bones (HP:0006392)2.44067325
44Urinary glycosaminoglycan excretion (HP:0003541)2.43068228
45Mucopolysacchariduria (HP:0008155)2.43068228
46Calf muscle hypertrophy (HP:0008981)2.40520951
47Atrial fibrillation (HP:0005110)2.37097402
48Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.36815945
49Centrally nucleated skeletal muscle fibers (HP:0003687)2.36507242
50Ulnar deviation of the wrist (HP:0003049)2.35062089
51Distal lower limb muscle weakness (HP:0009053)2.33996696
52Recurrent bacterial skin infections (HP:0005406)2.32353762
53Aneurysm (HP:0002617)2.32007136
54Muscle fiber inclusion bodies (HP:0100299)2.30798679
55Mitral valve prolapse (HP:0001634)2.30015163
56Axonal loss (HP:0003447)2.28195306
57Hypoplastic ischia (HP:0003175)2.27313031
58Abnormality of the vasculature of the conjunctiva (HP:0008054)2.27210988
59Nuclear cataract (HP:0100018)2.25963457
60Spinal rigidity (HP:0003306)2.24255862
61Eczematoid dermatitis (HP:0000976)2.21920340
62Malnutrition (HP:0004395)2.21554390
63Broad metatarsal (HP:0001783)2.21012928
64Lower limb amyotrophy (HP:0007210)2.20334443
65Bulbar palsy (HP:0001283)2.20133538
66Neck muscle weakness (HP:0000467)2.19783504
67Abnormality of skeletal muscle fiber size (HP:0012084)2.17224661
68Increased neuronal autofluorescent lipopigment (HP:0002074)2.16709506
69Increased variability in muscle fiber diameter (HP:0003557)2.16404517
70Primary atrial arrhythmia (HP:0001692)2.15606717
71Systemic lupus erythematosus (HP:0002725)2.15525303
72Distal upper limb amyotrophy (HP:0007149)2.12658146
73Upper limb amyotrophy (HP:0009129)2.12658146
74Long toe (HP:0010511)2.11596636
75Slender build (HP:0001533)2.11304622
76Wrist flexion contracture (HP:0001239)2.10723515
77Muscle hypertrophy of the lower extremities (HP:0008968)2.10372081
78Orchitis (HP:0100796)2.09292348
79Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.08906951
80Ulnar bowing (HP:0003031)2.08359759
81Supraventricular arrhythmia (HP:0005115)2.06925278
82Spondylolisthesis (HP:0003302)2.06675208
83Persistence of primary teeth (HP:0006335)2.05324347
84Genu recurvatum (HP:0002816)2.04978107
85Optic neuritis (HP:0100653)2.04670228
86Retrobulbar optic neuritis (HP:0100654)2.04670228
87Esophageal varix (HP:0002040)2.03380880
88Bundle branch block (HP:0011710)2.03130277
89Supraventricular tachycardia (HP:0004755)2.02641198
90Mildly elevated creatine phosphokinase (HP:0008180)2.01430521
91Vertebral compression fractures (HP:0002953)2.01410664
92Disinhibition (HP:0000734)1.97910964
93Gastrointestinal stroma tumor (HP:0100723)1.97706136
94Bladder diverticulum (HP:0000015)1.97059116
95Distal arthrogryposis (HP:0005684)1.95090014
96Soft skin (HP:0000977)1.93490102
97Atrophic scars (HP:0001075)1.93181430
98Dilated cardiomyopathy (HP:0001644)1.91858125
99Round ear (HP:0100830)1.91696058
100Abnormality of macrophages (HP:0004311)1.90396244
101Thin bony cortex (HP:0002753)1.89557958
102Neurofibrillary tangles (HP:0002185)1.89500924
103Metaphyseal cupping (HP:0003021)1.89287089
104Autoimmune thrombocytopenia (HP:0001973)1.87542994
105Radial bowing (HP:0002986)1.85277550
106Conjunctival telangiectasia (HP:0000524)1.84528664
107Abnormality of the calcaneus (HP:0008364)1.84510116
108Myocardial infarction (HP:0001658)1.84318535
109Abnormality of the ischium (HP:0003174)1.84130061
110Hip contracture (HP:0003273)1.83886717
111Apathy (HP:0000741)1.83802544
112Absent frontal sinuses (HP:0002688)1.81828161
113Spontaneous hematomas (HP:0007420)1.81669914
114Thick nail (HP:0001805)1.81510766
115Myoglobinuria (HP:0002913)1.79608000
116Dysmetric saccades (HP:0000641)1.78139640
117Ovoid vertebral bodies (HP:0003300)1.77996852
118Blue sclerae (HP:0000592)1.77856405
119Reduced subcutaneous adipose tissue (HP:0003758)1.77476585
120Fragile skin (HP:0001030)1.76674638
121Facial diplegia (HP:0001349)1.75530679
122Gingivitis (HP:0000230)1.75453351
123IgA deficiency (HP:0002720)1.75226639
124Limb-girdle muscle atrophy (HP:0003797)1.75025153
125Achilles tendon contracture (HP:0001771)1.74016845
126Vacuolated lymphocytes (HP:0001922)1.73776125
127Abnormal atrioventricular conduction (HP:0005150)1.73086439
128Urethral obstruction (HP:0000796)1.72845504
129Peritonitis (HP:0002586)1.72591831
130Thoracolumbar scoliosis (HP:0002944)1.72274504
131Joint stiffness (HP:0001387)1.72236793
132Nemaline bodies (HP:0003798)1.71962900
133Diminished motivation (HP:0000745)1.71818041
134Subacute progressive viral hepatitis (HP:0006572)1.71013002
135Striae distensae (HP:0001065)1.70817567
136Natal tooth (HP:0000695)1.69801057
137Emphysema (HP:0002097)1.68499987
138Elbow flexion contracture (HP:0002987)1.68162719
139Syringomyelia (HP:0003396)1.67366105
140Spinal cord lesions (HP:0100561)1.67366105
141Interstitial pulmonary disease (HP:0006530)1.63969317

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN5.63363688
2TRIB34.07948732
3PKN23.48990300
4GRK72.46992979
5DMPK2.26795222
6CDC42BPA2.13275029
7RIPK12.08760780
8LATS11.97775912
9NEK11.97097273
10EEF2K1.76798942
11CDK121.73508707
12MAP3K101.72269042
13TBK11.70000977
14PIK3CG1.68978548
15PDGFRA1.66296388
16TAOK21.60465907
17PTK61.60307705
18RPS6KA41.56076436
19STK31.55728528
20TYK21.55136774
21KIT1.50010486
22TRPM71.49955159
23BLK1.49905406
24NEK91.48501792
25OBSCN1.46078270
26ARAF1.44831617
27LRRK21.40573087
28PRPF4B1.36729302
29SCYL21.34725627
30DDR21.32618118
31ERN11.28221503
32NME21.28126189
33NEK21.27706579
34BMX1.25089208
35MAP2K31.23531809
36TGFBR21.22326917
37STK101.20658493
38CAMK1D1.19354233
39MAP3K31.18596667
40JAK31.16868185
41MATK1.15163143
42STK41.13107905
43JAK11.11849536
44MELK1.08857965
45TAOK11.05111800
46PAK41.04908850
47PDK31.03883317
48PDK41.03883317
49MTOR1.03197623
50LATS21.02540094
51IKBKE1.00082650
52PDGFRB0.98822008
53LIMK10.94237396
54ACVR1B0.92730941
55CDK60.89952161
56ICK0.86133499
57MAP3K50.84858070
58CSK0.83873786
59MUSK0.79116051
60LMTK20.79068713
61MAP3K80.78866276
62DAPK30.77144189
63MAPK70.76861946
64PLK40.76539638
65PAK20.76267544
66MAP3K140.74916776
67PDK20.73058570
68RIPK40.72198481
69TESK10.71970495
70PIM20.70684452
71HCK0.70655256
72PTK20.69315166
73PRKAA20.69227685
74CDK40.67890250
75MAPK120.67592849
76TGFBR10.66649351
77RPS6KA20.65969504
78IKBKB0.65599479
79ILK0.64504572
80PDPK10.64381424
81AKT30.63911694
82STK380.63906015
83SIK10.63683066
84PIK3CA0.63605366
85MAPK110.63463344
86CHUK0.63178245
87PTK2B0.62846345
88MARK30.62524264
89TAOK30.61150703
90BMPR20.61110437
91MAPKAPK30.60830181
92STK38L0.60642681
93MAPK40.59099335
94TESK20.59072727
95PIM10.57430046
96KSR20.57286528
97CAMK1G0.57203059
98ROCK10.56495345
99PRKD20.55616331
100IRAK40.54694641
101STK240.53818900
102PRKD10.53572082
103EPHB10.52530639
104MYLK0.52336803
105CDC70.52124732
106TTK0.51667089
107PHKG20.51337716
108PHKG10.51337716
109CSF1R0.50754411
110ALK0.49784724
111RPS6KL10.49675217
112RPS6KC10.49675217
113MAP3K60.49139048
114SGK30.48574275
115ZAP700.48155272
116MAP4K10.47515478
117MAP3K10.46387883
118EGFR0.46194967
119MAP3K130.45997711
120EPHA30.44992669
121PDK10.44920028
122FLT30.44779033
123MAPKAPK20.44605243
124ZAK0.43594561
125MOS0.41707714
126MARK20.41471575
127MAP3K70.41156547
128RET0.41113500
129IRAK30.40979042
130JAK20.40444867
131GSK3A0.40398518
132CAMKK10.39955080
133FGFR30.39612007
134RPS6KA60.38897938
135AURKB0.38184691
136FGR0.37699272
137RAF10.37294725
138ABL20.37014753

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.43812011
2Dilated cardiomyopathy_Homo sapiens_hsa054142.32570010
3Viral myocarditis_Homo sapiens_hsa054162.02617886
4Leishmaniasis_Homo sapiens_hsa051401.95365145
5Osteoclast differentiation_Homo sapiens_hsa043801.84052825
6Focal adhesion_Homo sapiens_hsa045101.81668839
7Small cell lung cancer_Homo sapiens_hsa052221.80302561
8ECM-receptor interaction_Homo sapiens_hsa045121.77550130
9Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.72105800
10Chronic myeloid leukemia_Homo sapiens_hsa052201.71474050
11Malaria_Homo sapiens_hsa051441.60060114
12Toxoplasmosis_Homo sapiens_hsa051451.59492188
13Lysosome_Homo sapiens_hsa041421.59107761
14Toll-like receptor signaling pathway_Homo sapiens_hsa046201.58823105
15Proteoglycans in cancer_Homo sapiens_hsa052051.57299503
16Amoebiasis_Homo sapiens_hsa051461.55298751
17Allograft rejection_Homo sapiens_hsa053301.52221445
18* Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.50242377
19Intestinal immune network for IgA production_Homo sapiens_hsa046721.48372265
20Tuberculosis_Homo sapiens_hsa051521.46425050
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.44866702
22AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.43856504
23Asthma_Homo sapiens_hsa053101.39637842
24Apoptosis_Homo sapiens_hsa042101.39004232
25Adherens junction_Homo sapiens_hsa045201.38451675
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.38165633
27Glycosaminoglycan degradation_Homo sapiens_hsa005311.36312695
28HIF-1 signaling pathway_Homo sapiens_hsa040661.35357085
29Leukocyte transendothelial migration_Homo sapiens_hsa046701.33322898
30mTOR signaling pathway_Homo sapiens_hsa041501.32658115
31Pancreatic cancer_Homo sapiens_hsa052121.32615031
32MicroRNAs in cancer_Homo sapiens_hsa052061.31635677
33NF-kappa B signaling pathway_Homo sapiens_hsa040641.30605792
34Legionellosis_Homo sapiens_hsa051341.28234606
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.27063654
36Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.26329957
37TNF signaling pathway_Homo sapiens_hsa046681.25172634
38Graft-versus-host disease_Homo sapiens_hsa053321.23423283
39Shigellosis_Homo sapiens_hsa051311.23405187
40Measles_Homo sapiens_hsa051621.22530532
41Influenza A_Homo sapiens_hsa051641.19562716
42Salmonella infection_Homo sapiens_hsa051321.17765473
43Phagosome_Homo sapiens_hsa041451.17522289
44Regulation of actin cytoskeleton_Homo sapiens_hsa048101.14803840
45Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.11054913
46Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.10763564
47B cell receptor signaling pathway_Homo sapiens_hsa046621.10660738
48Hepatitis B_Homo sapiens_hsa051611.10521995
49NOD-like receptor signaling pathway_Homo sapiens_hsa046211.08980892
50Autoimmune thyroid disease_Homo sapiens_hsa053201.07239218
51Insulin resistance_Homo sapiens_hsa049311.07060773
52Adipocytokine signaling pathway_Homo sapiens_hsa049201.03754968
53Platelet activation_Homo sapiens_hsa046111.03669867
54Central carbon metabolism in cancer_Homo sapiens_hsa052301.02431930
55VEGF signaling pathway_Homo sapiens_hsa043701.01498275
56Antigen processing and presentation_Homo sapiens_hsa046121.01326243
57Viral carcinogenesis_Homo sapiens_hsa052031.01047580
58Acute myeloid leukemia_Homo sapiens_hsa052210.99417401
59Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.98729114
60Thyroid hormone signaling pathway_Homo sapiens_hsa049190.96879765
61Pertussis_Homo sapiens_hsa051330.96310029
62Systemic lupus erythematosus_Homo sapiens_hsa053220.95689967
632-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.95152008
64Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.94982714
65Other glycan degradation_Homo sapiens_hsa005110.93511646
66African trypanosomiasis_Homo sapiens_hsa051430.91250095
67p53 signaling pathway_Homo sapiens_hsa041150.91135012
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90893452
69HTLV-I infection_Homo sapiens_hsa051660.90383242
70Glioma_Homo sapiens_hsa052140.87659359
71Renal cell carcinoma_Homo sapiens_hsa052110.86878660
72Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.86593032
73Non-small cell lung cancer_Homo sapiens_hsa052230.85706392
74Lysine degradation_Homo sapiens_hsa003100.85575804
75Neurotrophin signaling pathway_Homo sapiens_hsa047220.83729395
76Herpes simplex infection_Homo sapiens_hsa051680.83556156
77Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.83189327
78Bladder cancer_Homo sapiens_hsa052190.82735117
79Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.82234126
80Longevity regulating pathway - mammal_Homo sapiens_hsa042110.78306134
81FoxO signaling pathway_Homo sapiens_hsa040680.78242932
82Prion diseases_Homo sapiens_hsa050200.75790647
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.74889718
84RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74250725
85Insulin signaling pathway_Homo sapiens_hsa049100.74029543
86Sphingolipid metabolism_Homo sapiens_hsa006000.73136777
87Type II diabetes mellitus_Homo sapiens_hsa049300.72964111
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.72942809
89Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71972545
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.71087891
91Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70758333
92Caffeine metabolism_Homo sapiens_hsa002320.70309187
93Rheumatoid arthritis_Homo sapiens_hsa053230.70174398
94Colorectal cancer_Homo sapiens_hsa052100.68864489
95Endometrial cancer_Homo sapiens_hsa052130.68552182
96Cell cycle_Homo sapiens_hsa041100.68357949
97Notch signaling pathway_Homo sapiens_hsa043300.67400897
98Prolactin signaling pathway_Homo sapiens_hsa049170.67292235
99Endocytosis_Homo sapiens_hsa041440.67249987
100Chemokine signaling pathway_Homo sapiens_hsa040620.61976848
101Prostate cancer_Homo sapiens_hsa052150.61964586
102PI3K-Akt signaling pathway_Homo sapiens_hsa041510.61874001
103Melanoma_Homo sapiens_hsa052180.61808245
104PPAR signaling pathway_Homo sapiens_hsa033200.61082256
105AMPK signaling pathway_Homo sapiens_hsa041520.61041841
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60624969
107Sulfur metabolism_Homo sapiens_hsa009200.60227334
108Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.59406004
109TGF-beta signaling pathway_Homo sapiens_hsa043500.59367633
110Hepatitis C_Homo sapiens_hsa051600.58930223
111T cell receptor signaling pathway_Homo sapiens_hsa046600.58512105
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.57734302
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.57174412
114Phospholipase D signaling pathway_Homo sapiens_hsa040720.56022674
115cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54965401
116Pathways in cancer_Homo sapiens_hsa052000.53173681
117Epstein-Barr virus infection_Homo sapiens_hsa051690.53157296
118Carbon metabolism_Homo sapiens_hsa012000.52896417
119Hematopoietic cell lineage_Homo sapiens_hsa046400.52416269
120Dorso-ventral axis formation_Homo sapiens_hsa043200.51547755
121Type I diabetes mellitus_Homo sapiens_hsa049400.51229820
122GnRH signaling pathway_Homo sapiens_hsa049120.51189935
123Staphylococcus aureus infection_Homo sapiens_hsa051500.50242486
124Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.48530848
125MAPK signaling pathway_Homo sapiens_hsa040100.48394573
126Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.47965621
127Galactose metabolism_Homo sapiens_hsa000520.47553957
128Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.46249665

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