ARFGEF3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.45825917
2positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.95012186
3synaptic vesicle exocytosis (GO:0016079)4.79592133
4regulation of synaptic vesicle exocytosis (GO:2000300)4.61436455
5vocalization behavior (GO:0071625)4.58340293
6synaptic vesicle maturation (GO:0016188)4.49805847
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.40743599
8locomotory exploration behavior (GO:0035641)4.33283434
9neuron cell-cell adhesion (GO:0007158)4.31332193
10glutamate secretion (GO:0014047)4.27049310
11regulation of synaptic vesicle transport (GO:1902803)4.03492599
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.00411846
13protein localization to synapse (GO:0035418)3.94924434
14synaptic vesicle docking involved in exocytosis (GO:0016081)3.92078445
15regulation of glutamate receptor signaling pathway (GO:1900449)3.87719201
16regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.86643238
17ionotropic glutamate receptor signaling pathway (GO:0035235)3.80700320
18neurotransmitter secretion (GO:0007269)3.76842061
19neuronal action potential propagation (GO:0019227)3.75550835
20proline transport (GO:0015824)3.71754703
21detection of calcium ion (GO:0005513)3.71207526
22synaptic transmission, glutamatergic (GO:0035249)3.60199124
23regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.59540013
24glutamate receptor signaling pathway (GO:0007215)3.55022067
25exploration behavior (GO:0035640)3.51081419
26regulation of neuronal synaptic plasticity (GO:0048168)3.49666142
27cerebellar Purkinje cell differentiation (GO:0021702)3.46996057
28negative regulation of cytosolic calcium ion concentration (GO:0051481)3.46115882
29neuron-neuron synaptic transmission (GO:0007270)3.45508845
30activation of protein kinase A activity (GO:0034199)3.43603220
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.43338026
32regulation of long-term neuronal synaptic plasticity (GO:0048169)3.40010504
33protein targeting to Golgi (GO:0000042)3.39143376
34gamma-aminobutyric acid signaling pathway (GO:0007214)3.28148928
35chemosensory behavior (GO:0007635)3.26302195
36innervation (GO:0060384)3.26185027
37cellular potassium ion homeostasis (GO:0030007)3.23810639
38presynaptic membrane assembly (GO:0097105)3.23530797
39positive regulation of membrane potential (GO:0045838)3.22997619
40layer formation in cerebral cortex (GO:0021819)3.22185296
41membrane depolarization during action potential (GO:0086010)3.21753643
42long-term memory (GO:0007616)3.20801149
43neurotransmitter transport (GO:0006836)3.20061663
44neuron recognition (GO:0008038)3.16830874
45regulation of excitatory postsynaptic membrane potential (GO:0060079)3.16041855
46positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.15088783
47vesicle transport along microtubule (GO:0047496)3.14420506
48regulation of postsynaptic membrane potential (GO:0060078)3.14196805
49macroautophagy (GO:0016236)3.13571607
50insulin secretion (GO:0030073)3.12820771
51neurotransmitter-gated ion channel clustering (GO:0072578)3.11702427
52positive regulation of neurotransmitter transport (GO:0051590)3.09755667
53positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.07968388
54establishment of protein localization to Golgi (GO:0072600)3.07699133
55glandular epithelial cell differentiation (GO:0002067)3.06202567
56potassium ion homeostasis (GO:0055075)3.05545486
57regulation of vesicle fusion (GO:0031338)3.04584654
58regulation of calcium ion-dependent exocytosis (GO:0017158)3.03945811
59transmission of nerve impulse (GO:0019226)3.03803523
60gamma-aminobutyric acid transport (GO:0015812)3.03496952
61synaptic vesicle endocytosis (GO:0048488)3.02546652
62cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.02381353
63regulation of neurotransmitter secretion (GO:0046928)3.02303688
64postsynaptic membrane organization (GO:0001941)3.02275892
65long-term synaptic potentiation (GO:0060291)3.00332218
66regulation of synapse structural plasticity (GO:0051823)2.99155187
67neuromuscular process controlling posture (GO:0050884)2.99121278
68auditory receptor cell differentiation (GO:0042491)2.97892065
69regulation of synaptic plasticity (GO:0048167)2.94856090
70response to histamine (GO:0034776)2.94643509
71synapse assembly (GO:0007416)2.93058139
72retrograde transport, vesicle recycling within Golgi (GO:0000301)2.92708577
73dendrite morphogenesis (GO:0048813)2.92468433
74Golgi to endosome transport (GO:0006895)2.92406652
75regulation of Rac protein signal transduction (GO:0035020)2.90818753
76dendritic spine morphogenesis (GO:0060997)2.90735805
77positive regulation of synaptic transmission, GABAergic (GO:0032230)2.90609562
78axonal fasciculation (GO:0007413)2.89083824
79regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.89057396
80positive regulation of macroautophagy (GO:0016239)2.89037549
81presynaptic membrane organization (GO:0097090)2.88246839
82regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.87885380
83organelle transport along microtubule (GO:0072384)2.86995607
84neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.86208623
85calcium ion-dependent exocytosis (GO:0017156)2.84947466
86regulation of synaptic transmission, glutamatergic (GO:0051966)2.84796397
87inner ear receptor cell development (GO:0060119)2.84786128
88regulation of neurotransmitter levels (GO:0001505)2.84431523
89cerebellar Purkinje cell layer development (GO:0021680)2.84388504
90inositol phosphate catabolic process (GO:0071545)2.84083259
91social behavior (GO:0035176)2.82273266
92intraspecies interaction between organisms (GO:0051703)2.82273266
93membrane depolarization (GO:0051899)2.81892335
94membrane hyperpolarization (GO:0060081)2.80041276
95positive regulation of synapse maturation (GO:0090129)2.79914657
96regulation of exocytosis (GO:0017157)2.79203515
97membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.78334278
98positive regulation of exocytosis (GO:0045921)2.77684844
99regulation of neurotransmitter transport (GO:0051588)2.76669080
100G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.75682023
101suckling behavior (GO:0001967)2.74983340
102regulation of heart rate by cardiac conduction (GO:0086091)2.74006364
103cilium movement (GO:0003341)2.73539412
104regulation of type B pancreatic cell apoptotic process (GO:2000674)2.72380713
105synaptic vesicle transport (GO:0048489)2.72033380
106establishment of synaptic vesicle localization (GO:0097480)2.72033380
107positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.71219536
108synaptic transmission (GO:0007268)2.70697830
109startle response (GO:0001964)2.70626599
110COPI coating of Golgi vesicle (GO:0048205)2.70489727
111Golgi transport vesicle coating (GO:0048200)2.70489727
112negative regulation of synaptic transmission, GABAergic (GO:0032229)2.69955118
113epithelial cell fate commitment (GO:0072148)2.69685671
114embryonic retina morphogenesis in camera-type eye (GO:0060059)2.69328579
115glycerophospholipid catabolic process (GO:0046475)2.68847070
116female mating behavior (GO:0060180)2.68538553
117cell communication by electrical coupling (GO:0010644)2.67230826
118behavioral response to ethanol (GO:0048149)2.66673220
119myelin maintenance (GO:0043217)2.66200379
120polyol catabolic process (GO:0046174)2.64156127
121axoneme assembly (GO:0035082)2.63831254
122cardiac conduction (GO:0061337)2.62757496
123intestinal epithelial cell development (GO:0060576)2.62071972
124cilium or flagellum-dependent cell motility (GO:0001539)2.61542606
125auditory behavior (GO:0031223)2.59855474
126cerebellar granule cell differentiation (GO:0021707)2.57832742
127inositol phosphate-mediated signaling (GO:0048016)2.56555294
128signal release (GO:0023061)2.56459562
129axonemal dynein complex assembly (GO:0070286)2.54717053
130phosphorylated carbohydrate dephosphorylation (GO:0046838)2.53876901
131inositol phosphate dephosphorylation (GO:0046855)2.53876901
132regulation of autophagic vacuole assembly (GO:2000785)2.52803608
133regulation of neurotransmitter uptake (GO:0051580)2.52762983
134righting reflex (GO:0060013)2.52409504
135cellular ketone body metabolic process (GO:0046950)2.52257260
136positive regulation of neurotransmitter secretion (GO:0001956)2.51335754
137cochlea development (GO:0090102)2.51047611
138biotin metabolic process (GO:0006768)2.48316824
139peptide hormone processing (GO:0016486)2.46448547
140peptide hormone secretion (GO:0030072)2.44341510
141negative regulation of hormone biosynthetic process (GO:0032353)2.44032005
142endocrine pancreas development (GO:0031018)2.43322516
143positive regulation of gluconeogenesis (GO:0045722)2.42039104
144apical protein localization (GO:0045176)2.41436471
145membrane repolarization during action potential (GO:0086011)2.41021731
146L-alpha-amino acid transmembrane transport (GO:1902475)2.40327358
147positive regulation of insulin secretion (GO:0032024)2.39992527
148epithelial cilium movement (GO:0003351)2.38951461
149regulation of insulin secretion (GO:0050796)2.35843913
150regulation of sodium ion transmembrane transporter activity (GO:2000649)2.35110933
151peptide secretion (GO:0002790)2.34523146
152nitric oxide biosynthetic process (GO:0006809)2.33789378
153calcium ion import (GO:0070509)2.32469242
154protein localization to cilium (GO:0061512)2.32237865

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.81551294
2GBX2_23144817_ChIP-Seq_PC3_Human3.93913058
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.76814902
4REST_21632747_ChIP-Seq_MESCs_Mouse2.65444318
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.64220481
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.57696612
7SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26499252
8ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.25968715
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.23665889
10MTF2_20144788_ChIP-Seq_MESCs_Mouse2.20809169
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.19788919
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.17873884
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.17873884
14DROSHA_22980978_ChIP-Seq_HELA_Human2.14723809
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.14211119
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.11636594
17RARB_27405468_Chip-Seq_BRAIN_Mouse2.10416021
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.08375660
19CTBP2_25329375_ChIP-Seq_LNCAP_Human2.03086774
20REST_18959480_ChIP-ChIP_MESCs_Mouse2.02437899
21SMAD4_21799915_ChIP-Seq_A2780_Human1.93213918
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.90789562
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.87684217
24EED_16625203_ChIP-ChIP_MESCs_Mouse1.86668080
25EZH2_27294783_Chip-Seq_ESCs_Mouse1.85786405
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.84473407
27IGF1R_20145208_ChIP-Seq_DFB_Human1.83276226
28TAF15_26573619_Chip-Seq_HEK293_Human1.83078898
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.81850560
30SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.81691413
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.80411648
32FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.73547016
33ZNF274_21170338_ChIP-Seq_K562_Hela1.71565007
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.71560391
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.61719211
36NR3C1_23031785_ChIP-Seq_PC12_Mouse1.60183482
37PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.59685125
38P300_19829295_ChIP-Seq_ESCs_Human1.59327892
39FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.58134762
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.56958569
41POU3F2_20337985_ChIP-ChIP_501MEL_Human1.56953751
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.55405208
43STAT3_23295773_ChIP-Seq_U87_Human1.55220874
44AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.55161110
45FOXA1_25552417_ChIP-Seq_VCAP_Human1.51534846
46AR_21572438_ChIP-Seq_LNCaP_Human1.50242779
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.46714059
48ZNF217_24962896_ChIP-Seq_MCF-7_Human1.46341091
49OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45040708
50BMI1_23680149_ChIP-Seq_NPCS_Mouse1.44358188
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.44264820
52SOX2_21211035_ChIP-Seq_LN229_Gbm1.44182352
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44157810
54ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.42900030
55CDX2_19796622_ChIP-Seq_MESCs_Mouse1.39735753
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39220242
57BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.39075686
58GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35183779
59TCF4_23295773_ChIP-Seq_U87_Human1.34579625
60AR_25329375_ChIP-Seq_VCAP_Human1.34429975
61FOXM1_26456572_ChIP-Seq_MCF-7_Human1.34095897
62IKZF1_21737484_ChIP-ChIP_HCT116_Human1.33131199
63EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30395712
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.27820052
65AR_19668381_ChIP-Seq_PC3_Human1.27112275
66FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.26890295
67AHR_22903824_ChIP-Seq_MCF-7_Human1.26117095
68ESR2_21235772_ChIP-Seq_MCF-7_Human1.25288856
69HTT_18923047_ChIP-ChIP_STHdh_Human1.23468028
70SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20075731
71YAP1_20516196_ChIP-Seq_MESCs_Mouse1.19093938
72SMAD_19615063_ChIP-ChIP_OVARY_Human1.18702120
73ESR1_20079471_ChIP-ChIP_T-47D_Human1.16391451
74CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.14994297
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13986303
76PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13883728
77RUNX2_22187159_ChIP-Seq_PCA_Human1.13657477
78TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13592794
79FOXA2_19822575_ChIP-Seq_HepG2_Human1.13058345
80NANOG_18555785_Chip-Seq_ESCs_Mouse1.12779803
81RNF2_27304074_Chip-Seq_NSC_Mouse1.12234834
82ERG_21242973_ChIP-ChIP_JURKAT_Human1.11858361
83SMAD3_21741376_ChIP-Seq_ESCs_Human1.11651533
84MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11366916
85RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.10244543
86WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08420882
87FUS_26573619_Chip-Seq_HEK293_Human1.08341874
88ESR1_21235772_ChIP-Seq_MCF-7_Human1.08152319
89BCAT_22108803_ChIP-Seq_LS180_Human1.07704096
90CBX2_27304074_Chip-Seq_ESCs_Mouse1.07411420
91SMAD3_21741376_ChIP-Seq_HESCs_Human1.06542039
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06489502
93FLI1_27457419_Chip-Seq_LIVER_Mouse1.06486722
94MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.06143889
95RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.05407891
96STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04667911
97TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03952568
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.03554186
99CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03049516
100RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.02682885
101P53_22127205_ChIP-Seq_FIBROBLAST_Human1.02154537
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00071436
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98151203
104RING1B_27294783_Chip-Seq_ESCs_Mouse0.97525877
105TCF4_22108803_ChIP-Seq_LS180_Human0.97325868
106MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97156858
107NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97088917
108PRDM14_20953172_ChIP-Seq_ESCs_Human0.95816713
109TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.94668758
110PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.94473906
111ER_23166858_ChIP-Seq_MCF-7_Human0.93996200
112TP53_16413492_ChIP-PET_HCT116_Human0.93183385
113SMAD4_21741376_ChIP-Seq_HESCs_Human0.92868138
114KDM2B_26808549_Chip-Seq_REH_Human0.92847821
115EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91394864
116JUN_21703547_ChIP-Seq_K562_Human0.91121165
117RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.91100639
118VDR_22108803_ChIP-Seq_LS180_Human0.91086864

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.91105003
2MP0004270_analgesia3.95312589
3MP0003880_abnormal_central_pattern3.68980199
4MP0003635_abnormal_synaptic_transmissio3.49460091
5MP0009780_abnormal_chondrocyte_physiolo2.94035650
6MP0009745_abnormal_behavioral_response2.85630982
7MP0009046_muscle_twitch2.83733320
8MP0002063_abnormal_learning/memory/cond2.81123135
9MP0002734_abnormal_mechanical_nocicepti2.73290692
10MP0002064_seizures2.64210480
11MP0002909_abnormal_adrenal_gland2.56945474
12MP0001968_abnormal_touch/_nociception2.53669714
13MP0002572_abnormal_emotion/affect_behav2.51937453
14MP0005645_abnormal_hypothalamus_physiol2.37673663
15MP0002735_abnormal_chemical_nociception2.32182714
16MP0002272_abnormal_nervous_system2.31302435
17MP0010386_abnormal_urinary_bladder2.24416782
18MP0005423_abnormal_somatic_nervous2.20040423
19MP0002733_abnormal_thermal_nociception2.14493859
20MP0001501_abnormal_sleep_pattern2.12262808
21MP0005646_abnormal_pituitary_gland2.04632219
22MP0001486_abnormal_startle_reflex2.03478140
23MP0006276_abnormal_autonomic_nervous2.02398721
24MP0003123_paternal_imprinting1.98848896
25MP0001970_abnormal_pain_threshold1.97863073
26MP0001440_abnormal_grooming_behavior1.94621328
27MP0003122_maternal_imprinting1.88633474
28MP0002067_abnormal_sensory_capabilities1.85485728
29MP0002736_abnormal_nociception_after1.83560304
30MP0003283_abnormal_digestive_organ1.83249326
31MP0003787_abnormal_imprinting1.81129063
32MP0002184_abnormal_innervation1.80790240
33MP0002557_abnormal_social/conspecific_i1.78283131
34MP0004858_abnormal_nervous_system1.78171025
35MP0002822_catalepsy1.77231446
36MP0001984_abnormal_olfaction1.76142825
37MP0000569_abnormal_digit_pigmentation1.73210063
38MP0005386_behavior/neurological_phenoty1.63479794
39MP0004924_abnormal_behavior1.63479794
40MP0003879_abnormal_hair_cell1.62203516
41MP0004043_abnormal_pH_regulation1.57958230
42MP0004811_abnormal_neuron_physiology1.55177316
43MP0008569_lethality_at_weaning1.53642306
44MP0003329_amyloid_beta_deposits1.50257904
45MP0000013_abnormal_adipose_tissue1.50168838
46MP0000778_abnormal_nervous_system1.48851058
47MP0002693_abnormal_pancreas_physiology1.47344372
48MP0008877_abnormal_DNA_methylation1.45668286
49MP0005220_abnormal_exocrine_pancreas1.45289889
50MP0000955_abnormal_spinal_cord1.45246895
51MP0002163_abnormal_gland_morphology1.44268731
52MP0002837_dystrophic_cardiac_calcinosis1.41991696
53MP0003195_calcinosis1.40532756
54MP0003183_abnormal_peptide_metabolism1.39178694
55MP0001502_abnormal_circadian_rhythm1.38342884
56MP0002009_preneoplasia1.34781037
57MP0002882_abnormal_neuron_morphology1.30432407
58MP0002638_abnormal_pupillary_reflex1.29128127
59MP0001756_abnormal_urination1.26710334
60MP0002066_abnormal_motor_capabilities/c1.24606000
61MP0003633_abnormal_nervous_system1.22993181
62MP0001188_hyperpigmentation1.21004827
63MP0001944_abnormal_pancreas_morphology1.20806865
64MP0004145_abnormal_muscle_electrophysio1.18126825
65MP0010678_abnormal_skin_adnexa1.16104847
66MP0006072_abnormal_retinal_apoptosis1.15185168
67MP0005379_endocrine/exocrine_gland_phen1.14179974
68MP0001529_abnormal_vocalization1.14031907
69MP0004133_heterotaxia1.13576802
70MP0002229_neurodegeneration1.12261890
71MP0002877_abnormal_melanocyte_morpholog1.11689434
72MP0003172_abnormal_lysosome_physiology1.11274090
73MP0002876_abnormal_thyroid_physiology1.06402915
74MP0000631_abnormal_neuroendocrine_gland1.06399520
75MP0004019_abnormal_vitamin_homeostasis1.05868813
76MP0001986_abnormal_taste_sensitivity1.04861680
77MP0005448_abnormal_energy_balance1.03155780
78MP0004142_abnormal_muscle_tone1.01084708
79MP0010329_abnormal_lipoprotein_level1.00313294
80MP0003631_nervous_system_phenotype1.00278308
81MP0005535_abnormal_body_temperature0.98477437
82MP0003011_delayed_dark_adaptation0.96765170
83MP0005551_abnormal_eye_electrophysiolog0.95258212
84MP0001905_abnormal_dopamine_level0.95158076
85MP0010234_abnormal_vibrissa_follicle0.94532377
86MP0002152_abnormal_brain_morphology0.94507339
87MP0001299_abnormal_eye_distance/0.94480764
88MP0002069_abnormal_eating/drinking_beha0.94252983
89MP0005636_abnormal_mineral_homeostasis0.93674101
90MP0003045_fibrosis0.92604986
91MP0000516_abnormal_urinary_system0.91262767
92MP0005367_renal/urinary_system_phenotyp0.91262767
93MP0008961_abnormal_basal_metabolism0.90021493
94MP0005332_abnormal_amino_acid0.88696748
95MP0002139_abnormal_hepatobiliary_system0.88195291
96MP0002078_abnormal_glucose_homeostasis0.86430190
97MP0003634_abnormal_glial_cell0.85480038
98MP0004085_abnormal_heartbeat0.85102680
99MP0004885_abnormal_endolymph0.85001748
100MP0005187_abnormal_penis_morphology0.84608664
101MP0000003_abnormal_adipose_tissue0.84445823
102MP0004742_abnormal_vestibular_system0.84257582
103MP0000383_abnormal_hair_follicle0.83748826
104MP0000538_abnormal_urinary_bladder0.83279368
105MP0002653_abnormal_ependyma_morphology0.82996010
106MP0001765_abnormal_ion_homeostasis0.82068689
107MP0005365_abnormal_bile_salt0.81781335
108MP0001664_abnormal_digestion0.77272582
109MP0005310_abnormal_salivary_gland0.77221608
110MP0001963_abnormal_hearing_physiology0.76303966
111MP0000639_abnormal_adrenal_gland0.73981277
112MP0001485_abnormal_pinna_reflex0.73659059
113MP0003690_abnormal_glial_cell0.73252983
114MP0003953_abnormal_hormone_level0.73063419
115MP0003890_abnormal_embryonic-extraembry0.72952819
116MP0003121_genomic_imprinting0.70650622
117MP0003632_abnormal_nervous_system0.69055559
118MP0000678_abnormal_parathyroid_gland0.66623609
119MP0002752_abnormal_somatic_nervous0.66600362
120MP0005499_abnormal_olfactory_system0.65577031
121MP0005394_taste/olfaction_phenotype0.65577031
122MP0000604_amyloidosis0.63145054
123MP0001177_atelectasis0.62059802
124MP0002090_abnormal_vision0.61512194
125MP0005253_abnormal_eye_physiology0.60353922
126MP0008872_abnormal_physiological_respon0.58789079

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.18841082
2Focal seizures (HP:0007359)4.95213592
3Atonic seizures (HP:0010819)4.65172523
4Myokymia (HP:0002411)4.64675928
5Visual hallucinations (HP:0002367)4.60306617
6Febrile seizures (HP:0002373)4.18965646
7Epileptic encephalopathy (HP:0200134)4.12720697
8Absence seizures (HP:0002121)4.07604532
9Progressive cerebellar ataxia (HP:0002073)3.79405379
10Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.76472590
11Dialeptic seizures (HP:0011146)3.67009762
12Generalized tonic-clonic seizures (HP:0002069)3.60013464
13Action tremor (HP:0002345)3.41052473
14Epileptiform EEG discharges (HP:0011182)3.37597182
15Agitation (HP:0000713)3.36776356
16EEG with generalized epileptiform discharges (HP:0011198)3.28230523
17Truncal ataxia (HP:0002078)3.10332921
18Double outlet right ventricle (HP:0001719)3.09080234
19Congenital malformation of the right heart (HP:0011723)3.09080234
20Hypsarrhythmia (HP:0002521)3.08220528
21Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.97392995
22Supranuclear gaze palsy (HP:0000605)2.94899278
23Abnormality of aromatic amino acid family metabolism (HP:0004338)2.94167616
24Pheochromocytoma (HP:0002666)2.91280789
25Papilledema (HP:0001085)2.90101362
26Hyperventilation (HP:0002883)2.85117626
27Gaze-evoked nystagmus (HP:0000640)2.84549135
28Hypoglycemic coma (HP:0001325)2.80044476
29Ketoacidosis (HP:0001993)2.76917420
30Impaired smooth pursuit (HP:0007772)2.75220718
31Drooling (HP:0002307)2.73403604
32Excessive salivation (HP:0003781)2.73403604
33Broad-based gait (HP:0002136)2.71264330
34Depression (HP:0000716)2.70717530
35Rhinitis (HP:0012384)2.70717338
36Amblyopia (HP:0000646)2.68147205
37Anxiety (HP:0000739)2.62413098
38Abnormal respiratory epithelium morphology (HP:0012253)2.59736285
39Abnormal respiratory motile cilium morphology (HP:0005938)2.59736285
40Abnormal ciliary motility (HP:0012262)2.58341711
41Abnormal respiratory motile cilium physiology (HP:0012261)2.54145383
42Hyperglycemia (HP:0003074)2.53848918
43Ankle clonus (HP:0011448)2.50029570
44Abnormality of calcium-phosphate metabolism (HP:0100530)2.48522812
45Testicular atrophy (HP:0000029)2.47949895
46Dynein arm defect of respiratory motile cilia (HP:0012255)2.47074367
47Absent/shortened dynein arms (HP:0200106)2.47074367
48Impaired vibration sensation in the lower limbs (HP:0002166)2.46563100
49Genetic anticipation (HP:0003743)2.45745835
50Neuroendocrine neoplasm (HP:0100634)2.44162148
51Large for gestational age (HP:0001520)2.42378844
52Hyperinsulinemic hypoglycemia (HP:0000825)2.42353353
53Chronic bronchitis (HP:0004469)2.41076052
54Dysdiadochokinesis (HP:0002075)2.39779123
55Enlarged penis (HP:0000040)2.39719643
56Dysmetria (HP:0001310)2.39315207
57Hypothermia (HP:0002045)2.38733415
58Urinary bladder sphincter dysfunction (HP:0002839)2.38420715
59Failure to thrive in infancy (HP:0001531)2.37491491
60Increased circulating renin level (HP:0000848)2.37159557
61Testicular neoplasm (HP:0010788)2.36966547
62Poor eye contact (HP:0000817)2.36887102
63Decreased circulating renin level (HP:0003351)2.34078283
64Blue irides (HP:0000635)2.33417596
65Insidious onset (HP:0003587)2.29722916
66Termporal pattern (HP:0011008)2.29722916
67Abnormal social behavior (HP:0012433)2.28793308
68Impaired social interactions (HP:0000735)2.28793308
69Intestinal atresia (HP:0011100)2.28165497
70Hyperactive renin-angiotensin system (HP:0000841)2.27890772
71Abnormality of ocular smooth pursuit (HP:0000617)2.26554369
72Hyperphosphatemia (HP:0002905)2.25462228
73Abnormality of the corticospinal tract (HP:0002492)2.23219131
74Abnormal eating behavior (HP:0100738)2.23087618
75Hemiparesis (HP:0001269)2.18313442
76Vascular calcification (HP:0004934)2.17224704
77Abnormality of vitamin B metabolism (HP:0004340)2.16990580
78Postural instability (HP:0002172)2.15971557
79Abnormality of renin-angiotensin system (HP:0000847)2.12775374
80Hyperkalemia (HP:0002153)2.12672576
81Hypoglycemic seizures (HP:0002173)2.12646165
82Abnormality of vitamin metabolism (HP:0100508)2.12314260
83Sleep apnea (HP:0010535)2.09508392
84Abnormality of binocular vision (HP:0011514)2.08756359
85Diplopia (HP:0000651)2.08756359
86Protruding tongue (HP:0010808)2.07979221
87Nephronophthisis (HP:0000090)2.06951393
88Spastic gait (HP:0002064)2.06915314
89Bradykinesia (HP:0002067)2.06725867
90Absent speech (HP:0001344)2.05785681
91Gait imbalance (HP:0002141)2.04389207
92Limb dystonia (HP:0002451)2.03669762
93Macroorchidism (HP:0000053)2.02941321
94Cerebral inclusion bodies (HP:0100314)2.01995889
95Scanning speech (HP:0002168)2.01436604
96Mutism (HP:0002300)2.00800809
97Hyperthyroidism (HP:0000836)1.99706436
98Syncope (HP:0001279)1.96546047
99Psychosis (HP:0000709)1.96143853
100Abnormal pancreas size (HP:0012094)1.95967946
101Abnormality of the renal cortex (HP:0011035)1.95609429
102Neoplasm of the adrenal cortex (HP:0100641)1.94881296
103Symptomatic seizures (HP:0011145)1.92708954
104Obstructive sleep apnea (HP:0002870)1.91406877
105Generalized hypopigmentation of hair (HP:0011358)1.90571288
106Insulin-resistant diabetes mellitus (HP:0000831)1.89738152
107Postural tremor (HP:0002174)1.89439661
108Type II lissencephaly (HP:0007260)1.89140782
109Restlessness (HP:0000711)1.89006056
110Cortical visual impairment (HP:0100704)1.87970768
111Retinal atrophy (HP:0001105)1.87860071
112Hypoventilation (HP:0002791)1.87394099
113Impaired vibratory sensation (HP:0002495)1.87342395
114Pancreatic fibrosis (HP:0100732)1.86862636
115Hyperaldosteronism (HP:0000859)1.86596508
116Abnormality of salivation (HP:0100755)1.85890070
117Increased CSF protein (HP:0002922)1.85821814
118Urethral obstruction (HP:0000796)1.85812837
119Stereotypic behavior (HP:0000733)1.85544847
120Neurofibrillary tangles (HP:0002185)1.85401581
121Torticollis (HP:0000473)1.85017443
122Resting tremor (HP:0002322)1.84628942
123Ketosis (HP:0001946)1.84568194
124Calf muscle hypertrophy (HP:0008981)1.83826501
125Muscular hypotonia of the trunk (HP:0008936)1.83343649
126Menstrual irregularities (HP:0000858)1.81770159
127Akinesia (HP:0002304)1.81048053
128Bronchiectasis (HP:0002110)1.79907076
129Late onset (HP:0003584)1.79773682
130Exotropia (HP:0000577)1.79733999
131Retinal dysplasia (HP:0007973)1.78351730
132Polyphagia (HP:0002591)1.78273995
133Hypercortisolism (HP:0001578)1.77958791
134Urinary urgency (HP:0000012)1.77704992
135Medial flaring of the eyebrow (HP:0010747)1.76631616
136Abnormal drinking behavior (HP:0030082)1.76130660
137Polydipsia (HP:0001959)1.76130660
138Methylmalonic acidemia (HP:0002912)1.75694467
139Dysmetric saccades (HP:0000641)1.75437249
140Abnormality of the renal medulla (HP:0100957)1.75431993
141Septate vagina (HP:0001153)1.75323813
142Papillary thyroid carcinoma (HP:0002895)1.75306987
143Bronchomalacia (HP:0002780)1.73740847
144Open mouth (HP:0000194)1.72302169
145Bradycardia (HP:0001662)1.71922517
146Congenital primary aphakia (HP:0007707)1.71861613
147Degeneration of the lateral corticospinal tracts (HP:0002314)1.71623341
148Gait ataxia (HP:0002066)1.70721949
149Specific learning disability (HP:0001328)1.70257341
150Prolonged QT interval (HP:0001657)1.69799857
151Intention tremor (HP:0002080)1.68988909
152Lower limb muscle weakness (HP:0007340)1.68932355
153Abnormal EKG (HP:0003115)1.68906258
154Progressive inability to walk (HP:0002505)1.68446134
155Neuronal loss in central nervous system (HP:0002529)1.68036159

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.01677202
2MAP3K93.35607407
3MAP3K43.15143560
4CAMK1D3.10144699
5MARK12.76310891
6EPHA42.73850296
7CASK2.54474366
8MAP2K72.49996139
9NTRK12.38304425
10TNK22.31588296
11MINK12.30867468
12INSRR2.25657488
13FGFR22.13800850
14AKT32.02019135
15PRKD31.92569179
16MAP3K21.91913492
17DAPK21.89582152
18FRK1.88947006
19RIPK41.87523230
20NTRK21.86807520
21CAMKK21.81489896
22STK391.71380546
23MAP2K41.71168827
24TAOK31.66663817
25PAK61.64934595
26KSR21.62632917
27PNCK1.61323910
28GRK11.56988660
29MAP3K121.52395725
30CAMKK11.51687514
31MST41.48567247
32MAPK131.46287186
33GRK51.44689973
34ARAF1.40651298
35CDK51.38568991
36UHMK11.38473605
37DAPK11.26593577
38SCYL21.26324609
39PRKCI1.22127149
40STK38L1.19895316
41KSR11.19750192
42MAP2K61.19660882
43SGK21.15010334
44WNK31.14111439
45TNIK1.11009685
46PLK21.10773718
47PINK11.10500989
48CAMK2A1.07864720
49FGFR31.05477721
50SGK4941.05225396
51SGK2231.05225396
52PRKCG1.03418455
53RET0.98730354
54BMPR20.98357774
55CDC42BPA0.97262036
56CAMK1G0.97087112
57STK380.96062179
58CAMK2B0.94683638
59HIPK20.94612415
60EEF2K0.93762931
61PAK30.93613526
62MAP3K10.93171476
63PRKCH0.92287980
64PRKD20.92219855
65MAP4K20.88606743
66EPHA20.87577148
67EPHA30.84054766
68BRAF0.83970013
69SGK30.81884622
70CSNK1G20.78739403
71PRKCE0.75298764
72PRPF4B0.73904803
73SGK10.73535801
74FER0.72588326
75CSNK1G10.71802239
76CAMK2D0.70551551
77CAMK10.69375494
78FES0.69015050
79SIK20.68139506
80NLK0.67845170
81PHKG20.67731830
82PHKG10.67731830
83MARK20.67176749
84WNK10.66201163
85ERBB30.63752186
86STK110.63484498
87RPS6KA20.62521763
88ACVR1B0.61025155
89NEK60.60031896
90OXSR10.59563603
91PRKAA20.58198184
92MAP3K130.58155808
93BMPR1B0.58110318
94DYRK1A0.56123571
95CSNK1E0.54427904
96NME10.54329995
97PTK20.54000248
98IRAK20.53894974
99CSNK1G30.53636901
100ADRBK20.52959761
101BCR0.52536100
102WNK40.52394637
103LATS20.52224466
104RPS6KA30.52137869
105RAF10.51300244
106PDPK10.49565496
107CDK190.49498080
108PDK10.48410730
109CSNK1A10.47430948
110CDK140.46190121
111LMTK20.46055984
112PASK0.45408640
113YES10.44973158
114CDK180.44599400
115TAOK10.43678766
116CAMK2G0.43572020
117MAPK100.43176253
118STK30.43113924
119MAP2K10.43108449
120TRPM70.42227889
121MAPK150.41791442
122MKNK20.41604182
123ADRBK10.41122532
124STK240.41014164
125CDK150.40754453
126CSNK1A1L0.40135131
127PTK2B0.39103206
128GRK70.38505424
129PRKCB0.37335206
130PRKG10.36736080
131PRKACA0.35741310
132PRKCZ0.34973693
133PRKAA10.34770606
134CSNK1D0.33347319
135ERBB20.32319588

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.23197691
2Synaptic vesicle cycle_Homo sapiens_hsa047212.98922595
3Insulin secretion_Homo sapiens_hsa049112.80685413
4Long-term potentiation_Homo sapiens_hsa047202.47518844
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.46434505
6Circadian entrainment_Homo sapiens_hsa047132.46432494
7Amphetamine addiction_Homo sapiens_hsa050312.45106210
8GABAergic synapse_Homo sapiens_hsa047272.42913973
9Morphine addiction_Homo sapiens_hsa050322.23416157
10Glutamatergic synapse_Homo sapiens_hsa047242.22348810
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.22163652
12Olfactory transduction_Homo sapiens_hsa047402.18107658
13Vitamin B6 metabolism_Homo sapiens_hsa007502.11024244
14Dopaminergic synapse_Homo sapiens_hsa047282.10372369
15Maturity onset diabetes of the young_Homo sapiens_hsa049502.08842875
16Taste transduction_Homo sapiens_hsa047422.06641867
17Salivary secretion_Homo sapiens_hsa049701.94889316
18Cholinergic synapse_Homo sapiens_hsa047251.87414800
19Type II diabetes mellitus_Homo sapiens_hsa049301.86651770
20Cocaine addiction_Homo sapiens_hsa050301.82826768
21Serotonergic synapse_Homo sapiens_hsa047261.79270438
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.75883065
23Collecting duct acid secretion_Homo sapiens_hsa049661.70874142
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.70172739
25Renin secretion_Homo sapiens_hsa049241.67045349
26Fatty acid biosynthesis_Homo sapiens_hsa000611.64263078
27Vibrio cholerae infection_Homo sapiens_hsa051101.61324796
28Gastric acid secretion_Homo sapiens_hsa049711.60911100
29Long-term depression_Homo sapiens_hsa047301.58502742
30Butanoate metabolism_Homo sapiens_hsa006501.45554960
31Pancreatic secretion_Homo sapiens_hsa049721.42845830
32Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.42513635
33Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.41118399
34Oxytocin signaling pathway_Homo sapiens_hsa049211.35501827
35Calcium signaling pathway_Homo sapiens_hsa040201.34185497
36Folate biosynthesis_Homo sapiens_hsa007901.34160529
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.31264834
38GnRH signaling pathway_Homo sapiens_hsa049121.30339547
39Estrogen signaling pathway_Homo sapiens_hsa049151.25073419
40Histidine metabolism_Homo sapiens_hsa003401.24419907
41Phosphatidylinositol signaling system_Homo sapiens_hsa040701.22636756
42beta-Alanine metabolism_Homo sapiens_hsa004101.20699922
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18385578
44cAMP signaling pathway_Homo sapiens_hsa040241.15762116
45Carbohydrate digestion and absorption_Homo sapiens_hsa049731.15527862
46Gap junction_Homo sapiens_hsa045401.13959581
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.13423572
48Type I diabetes mellitus_Homo sapiens_hsa049401.10324432
49Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.09702671
50cGMP-PKG signaling pathway_Homo sapiens_hsa040221.09245987
51Thyroid hormone synthesis_Homo sapiens_hsa049181.07089196
52Arginine biosynthesis_Homo sapiens_hsa002201.06600383
53Sphingolipid metabolism_Homo sapiens_hsa006001.06237939
54Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.03655970
55ABC transporters_Homo sapiens_hsa020101.03165463
56Vascular smooth muscle contraction_Homo sapiens_hsa042701.02460185
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.02349359
58Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.96785694
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.95305448
60Propanoate metabolism_Homo sapiens_hsa006400.95017107
61Glioma_Homo sapiens_hsa052140.93289656
62Melanogenesis_Homo sapiens_hsa049160.93137609
63ErbB signaling pathway_Homo sapiens_hsa040120.92514510
64Tight junction_Homo sapiens_hsa045300.90803640
65Dorso-ventral axis formation_Homo sapiens_hsa043200.88340110
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88319784
67Fatty acid metabolism_Homo sapiens_hsa012120.85897820
68Ether lipid metabolism_Homo sapiens_hsa005650.84572281
69Protein export_Homo sapiens_hsa030600.82555374
70Glucagon signaling pathway_Homo sapiens_hsa049220.79648614
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79251619
72Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76257331
73Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.75634631
74Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75148053
75Arginine and proline metabolism_Homo sapiens_hsa003300.74919072
76Phototransduction_Homo sapiens_hsa047440.74473440
77Tryptophan metabolism_Homo sapiens_hsa003800.73634518
78Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71894933
79Cardiac muscle contraction_Homo sapiens_hsa042600.71123994
80Axon guidance_Homo sapiens_hsa043600.71004292
81Circadian rhythm_Homo sapiens_hsa047100.69930175
82Peroxisome_Homo sapiens_hsa041460.67762324
83Oocyte meiosis_Homo sapiens_hsa041140.65313678
84Choline metabolism in cancer_Homo sapiens_hsa052310.65007310
85mTOR signaling pathway_Homo sapiens_hsa041500.64193357
86Sulfur metabolism_Homo sapiens_hsa009200.63194962
87Inositol phosphate metabolism_Homo sapiens_hsa005620.62567056
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.62280755
89MAPK signaling pathway_Homo sapiens_hsa040100.61834929
90Renin-angiotensin system_Homo sapiens_hsa046140.60714303
91Selenocompound metabolism_Homo sapiens_hsa004500.60358454
92Phenylalanine metabolism_Homo sapiens_hsa003600.60270194
93Linoleic acid metabolism_Homo sapiens_hsa005910.59705940
94Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.59439783
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.59079437
96AMPK signaling pathway_Homo sapiens_hsa041520.58273237
97Oxidative phosphorylation_Homo sapiens_hsa001900.57954450
98Dilated cardiomyopathy_Homo sapiens_hsa054140.56910441
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.56856540
100Alcoholism_Homo sapiens_hsa050340.55166391
101Insulin signaling pathway_Homo sapiens_hsa049100.52712729
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52675747
103Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.52622618
104Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50789966
105Ras signaling pathway_Homo sapiens_hsa040140.49619500
106Alzheimers disease_Homo sapiens_hsa050100.49492113
107Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.49333181
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48554474
109Endometrial cancer_Homo sapiens_hsa052130.48400171
110Prolactin signaling pathway_Homo sapiens_hsa049170.48252471
111Primary bile acid biosynthesis_Homo sapiens_hsa001200.47839265
112Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47643666
113alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.47344449
114Ovarian steroidogenesis_Homo sapiens_hsa049130.45149033
115Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.45043757
116Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44598724
117Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44440986
118VEGF signaling pathway_Homo sapiens_hsa043700.42533667
119Glycerophospholipid metabolism_Homo sapiens_hsa005640.42244640
120Insulin resistance_Homo sapiens_hsa049310.42114860
121Prion diseases_Homo sapiens_hsa050200.42097331
122Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41999939
123Lysine degradation_Homo sapiens_hsa003100.39669395
124Steroid biosynthesis_Homo sapiens_hsa001000.39317079
125Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38098262
126N-Glycan biosynthesis_Homo sapiens_hsa005100.37888356
127Sphingolipid signaling pathway_Homo sapiens_hsa040710.37779683
128Renal cell carcinoma_Homo sapiens_hsa052110.37648006
129Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.33133471
130Rap1 signaling pathway_Homo sapiens_hsa040150.32124807
131Endocytosis_Homo sapiens_hsa041440.31496412
132Wnt signaling pathway_Homo sapiens_hsa043100.31158334
133Bile secretion_Homo sapiens_hsa049760.29027434
134Lysosome_Homo sapiens_hsa041420.28675682
135Non-small cell lung cancer_Homo sapiens_hsa052230.28328856
136Mineral absorption_Homo sapiens_hsa049780.26623048
137Regulation of autophagy_Homo sapiens_hsa041400.24154445

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