AOX2P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-fucose metabolic process (GO:0042354)5.11526818
2L-fucose catabolic process (GO:0042355)5.11526818
3fucose catabolic process (GO:0019317)5.11526818
4DNA deamination (GO:0045006)4.23857624
5cell wall macromolecule metabolic process (GO:0044036)4.10883812
6negative regulation of thymocyte apoptotic process (GO:0070244)3.96043140
7tryptophan catabolic process (GO:0006569)3.88663001
8indole-containing compound catabolic process (GO:0042436)3.88663001
9indolalkylamine catabolic process (GO:0046218)3.88663001
10tryptophan metabolic process (GO:0006568)3.67647034
11positive regulation of granulocyte differentiation (GO:0030854)3.66078472
12indolalkylamine metabolic process (GO:0006586)3.65645309
13seminiferous tubule development (GO:0072520)3.65015489
14cilium or flagellum-dependent cell motility (GO:0001539)3.47292628
15purinergic nucleotide receptor signaling pathway (GO:0035590)3.46315586
16mannosylation (GO:0097502)3.45248452
17axoneme assembly (GO:0035082)3.39999024
18detection of light stimulus involved in sensory perception (GO:0050962)3.39976875
19detection of light stimulus involved in visual perception (GO:0050908)3.39976875
20piRNA metabolic process (GO:0034587)3.38461379
21negative regulation of growth of symbiont in host (GO:0044130)3.33206424
22negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.33206424
23modulation of growth of symbiont involved in interaction with host (GO:0044144)3.33206424
24regulation of growth of symbiont in host (GO:0044126)3.33206424
25mitochondrial respiratory chain complex I assembly (GO:0032981)3.30312126
26NADH dehydrogenase complex assembly (GO:0010257)3.30312126
27mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.30312126
28respiratory chain complex IV assembly (GO:0008535)3.29511692
29cell wall macromolecule catabolic process (GO:0016998)3.23989252
30protein complex biogenesis (GO:0070271)3.23756200
31amine catabolic process (GO:0009310)3.23255049
32cellular biogenic amine catabolic process (GO:0042402)3.23255049
33positive regulation of B cell differentiation (GO:0045579)3.20370848
34L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.17590587
35positive regulation of defense response to virus by host (GO:0002230)3.08731116
36cytochrome complex assembly (GO:0017004)3.07642484
37mast cell degranulation (GO:0043303)3.04376740
38mast cell activation involved in immune response (GO:0002279)3.04376740
39neutrophil mediated immunity (GO:0002446)3.01267695
40adenosine metabolic process (GO:0046085)3.00101153
41rRNA catabolic process (GO:0016075)2.98731711
42protein polyglutamylation (GO:0018095)2.95101855
43positive regulation of prostaglandin secretion (GO:0032308)2.92387271
44prenylation (GO:0097354)2.92063759
45protein prenylation (GO:0018342)2.92063759
46negative regulation of telomere maintenance (GO:0032205)2.91917984
47preassembly of GPI anchor in ER membrane (GO:0016254)2.89873906
48mitochondrial respiratory chain complex assembly (GO:0033108)2.86997452
49DNA methylation involved in gamete generation (GO:0043046)2.85447752
50disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.83574142
51killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.83574142
52photoreceptor cell maintenance (GO:0045494)2.81076494
53behavioral response to nicotine (GO:0035095)2.76566713
54neural tube formation (GO:0001841)2.76340390
55ubiquinone biosynthetic process (GO:0006744)2.76326641
56cellular response to exogenous dsRNA (GO:0071360)2.74011695
57detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.73339409
58amino acid salvage (GO:0043102)2.72162339
59L-methionine salvage (GO:0071267)2.72162339
60L-methionine biosynthetic process (GO:0071265)2.72162339
61regulation of female gonad development (GO:2000194)2.71287081
62kynurenine metabolic process (GO:0070189)2.70212616
63DNA double-strand break processing (GO:0000729)2.69497785
64negative regulation of phagocytosis (GO:0050765)2.68937409
65positive regulation of fatty acid transport (GO:2000193)2.68635427
66regulation of thymocyte apoptotic process (GO:0070243)2.68484699
67epithelial cilium movement (GO:0003351)2.66036521
68positive regulation of icosanoid secretion (GO:0032305)2.62000249
69negative regulation of B cell apoptotic process (GO:0002903)2.60876521
70sperm motility (GO:0030317)2.60405366
71platelet dense granule organization (GO:0060155)2.60351414
72Peyers patch development (GO:0048541)2.59908149
73mucosal-associated lymphoid tissue development (GO:0048537)2.59908149
74killing of cells of other organism (GO:0031640)2.59246642
75disruption of cells of other organism (GO:0044364)2.59246642
76RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.57878413
77mast cell activation (GO:0045576)2.55814585
78replication fork processing (GO:0031297)2.54895814
79cardiolipin metabolic process (GO:0032048)2.54603072
80regulation of B cell apoptotic process (GO:0002902)2.53515404
81protein K11-linked deubiquitination (GO:0035871)2.50686521
82aromatic amino acid family catabolic process (GO:0009074)2.50533325
83reactive oxygen species biosynthetic process (GO:1903409)2.50003306
84peptidyl-histidine modification (GO:0018202)2.49819184
85DNA integration (GO:0015074)2.49324947
86regulation of granulocyte differentiation (GO:0030852)2.48726907
87DNA dealkylation (GO:0035510)2.47754972
88response to hydroperoxide (GO:0033194)2.47638944
89cellular response to ethanol (GO:0071361)2.46763172
90response to pheromone (GO:0019236)2.46692722
91centriole replication (GO:0007099)2.46245775
92DNA modification (GO:0006304)2.45751397
93regulation of telomere maintenance (GO:0032204)2.45362410
94purine deoxyribonucleotide catabolic process (GO:0009155)2.45106598
95cellular ketone body metabolic process (GO:0046950)2.44865406
96GPI anchor metabolic process (GO:0006505)2.42925853
97regulation of hexokinase activity (GO:1903299)2.42685725
98regulation of glucokinase activity (GO:0033131)2.42685725
99negative regulation of mast cell activation (GO:0033004)2.40753891
100myeloid leukocyte mediated immunity (GO:0002444)2.39237041

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.75123065
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.58028390
3IGF1R_20145208_ChIP-Seq_DFB_Human3.20463975
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.85554567
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.66875212
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.62905742
7GBX2_23144817_ChIP-Seq_PC3_Human2.33838730
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.28976987
9VDR_22108803_ChIP-Seq_LS180_Human2.26925113
10EWS_26573619_Chip-Seq_HEK293_Human2.26899205
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.14634658
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.09794996
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.02817253
14ER_23166858_ChIP-Seq_MCF-7_Human1.90974125
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.89464774
16FUS_26573619_Chip-Seq_HEK293_Human1.89369718
17IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.84294703
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.83627718
19CBP_20019798_ChIP-Seq_JUKART_Human1.81634894
20IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.81634894
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.79793262
22LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.78981116
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.78300504
24P300_19829295_ChIP-Seq_ESCs_Human1.77477273
25EZH2_22144423_ChIP-Seq_EOC_Human1.75951169
26RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.68198412
27TAF15_26573619_Chip-Seq_HEK293_Human1.66972637
28SALL1_21062744_ChIP-ChIP_HESCs_Human1.60607873
29EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.58735413
30TP53_22573176_ChIP-Seq_HFKS_Human1.58434556
31NOTCH1_21737748_ChIP-Seq_TLL_Human1.56349764
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53684358
33IRF1_19129219_ChIP-ChIP_H3396_Human1.53166406
34GABP_17652178_ChIP-ChIP_JURKAT_Human1.47818061
35VDR_23849224_ChIP-Seq_CD4+_Human1.44826240
36NANOG_19829295_ChIP-Seq_ESCs_Human1.43996873
37SOX2_19829295_ChIP-Seq_ESCs_Human1.43996873
38MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.40430676
39GATA3_26560356_Chip-Seq_TH2_Human1.40127880
40CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.38050057
41BCAT_22108803_ChIP-Seq_LS180_Human1.37999111
42EGR1_23403033_ChIP-Seq_LIVER_Mouse1.37474429
43FOXA1_25329375_ChIP-Seq_VCAP_Human1.36666239
44FOXA1_27270436_Chip-Seq_PROSTATE_Human1.36666239
45UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36600192
46KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.36013831
47PCGF2_27294783_Chip-Seq_ESCs_Mouse1.35690225
48AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32525967
49MYC_18940864_ChIP-ChIP_HL60_Human1.31546268
50STAT3_23295773_ChIP-Seq_U87_Human1.30933529
51GATA3_21878914_ChIP-Seq_MCF-7_Human1.29072334
52TCF4_23295773_ChIP-Seq_U87_Human1.28739380
53FOXA1_21572438_ChIP-Seq_LNCaP_Human1.28059476
54NCOR_22424771_ChIP-Seq_293T_Human1.27741625
55AR_20517297_ChIP-Seq_VCAP_Human1.26172809
56MYB_26560356_Chip-Seq_TH2_Human1.26041757
57FOXP3_21729870_ChIP-Seq_TREG_Human1.25267470
58TCF4_22108803_ChIP-Seq_LS180_Human1.23579756
59AR_25329375_ChIP-Seq_VCAP_Human1.23186513
60EST1_17652178_ChIP-ChIP_JURKAT_Human1.22734019
61IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.22147716
62PRDM14_20953172_ChIP-Seq_ESCs_Human1.22009252
63MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21919789
64POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20828746
65TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20828746
66GATA3_27048872_Chip-Seq_THYMUS_Human1.20499893
67STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.20186441
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18228182
69SMAD4_21799915_ChIP-Seq_A2780_Human1.17445344
70NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15587982
71SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14334756
72PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13795256
73RUNX_20019798_ChIP-Seq_JUKART_Human1.13344920
74VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.12187611
75SRF_21415370_ChIP-Seq_HL-1_Mouse1.11202166
76EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10182507
77GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10133469
78NANOG_20526341_ChIP-Seq_ESCs_Human1.07863956
79SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.07424570
80IRF8_21731497_ChIP-ChIP_J774_Mouse1.07418640
81HOXB7_26014856_ChIP-Seq_BT474_Human1.04607697
82SCL_19346495_ChIP-Seq_HPC-7_Human1.04065660
83TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03326240
84RUNX2_22187159_ChIP-Seq_PCA_Human1.02180815
85CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.00911035
86FLI1_21867929_ChIP-Seq_TH2_Mouse1.00113622
87TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99680645
88EZH2_27294783_Chip-Seq_NPCs_Mouse0.99435245
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98467675
90PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.97917258
91SUZ12_27294783_Chip-Seq_NPCs_Mouse0.97730887
92AUTS2_25519132_ChIP-Seq_293T-REX_Human0.96932946
93ETV2_25802403_ChIP-Seq_MESCs_Mouse0.96454365
94TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.95429457
95RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.93736197
96RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.93265128
97CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.92835908
98ELK1_19687146_ChIP-ChIP_HELA_Human0.92285759
99SMRT_27268052_Chip-Seq_Bcells_Human0.91754920
100CDX2_22108803_ChIP-Seq_LS180_Human0.91492587

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009278_abnormal_bone_marrow3.14178694
2MP0008877_abnormal_DNA_methylation2.90794995
3MP0002876_abnormal_thyroid_physiology2.65382773
4MP0001986_abnormal_taste_sensitivity2.46302900
5MP0003787_abnormal_imprinting2.33559618
6MP0005075_abnormal_melanosome_morpholog2.29546681
7MP0008057_abnormal_DNA_replication2.28897330
8MP0005397_hematopoietic_system_phenotyp2.25278746
9MP0001545_abnormal_hematopoietic_system2.25278746
10MP0008872_abnormal_physiological_respon2.13568134
11MP0001968_abnormal_touch/_nociception2.12611690
12MP0000569_abnormal_digit_pigmentation2.09026796
13MP0000372_irregular_coat_pigmentation2.04499140
14MP0005671_abnormal_response_to2.02285206
15MP0008875_abnormal_xenobiotic_pharmacok2.01147982
16MP0006072_abnormal_retinal_apoptosis1.99953164
17MP0003195_calcinosis1.94951717
18MP0005645_abnormal_hypothalamus_physiol1.88171408
19MP0005551_abnormal_eye_electrophysiolog1.85197249
20MP0008058_abnormal_DNA_repair1.78695015
21MP0005646_abnormal_pituitary_gland1.73223353
22MP0001835_abnormal_antigen_presentation1.73071730
23MP0005410_abnormal_fertilization1.71751350
24MP0004147_increased_porphyrin_level1.66846478
25MP0003252_abnormal_bile_duct1.56975529
26MP0002736_abnormal_nociception_after1.56504369
27MP0003718_maternal_effect1.54546750
28MP0001764_abnormal_homeostasis1.47854863
29MP0009785_altered_susceptibility_to1.46371760
30MP0001501_abnormal_sleep_pattern1.44245569
31MP0005174_abnormal_tail_pigmentation1.42879756
32MP0002132_abnormal_respiratory_system1.42181564
33MP0002160_abnormal_reproductive_system1.41216076
34MP0002396_abnormal_hematopoietic_system1.41023598
35MP0001800_abnormal_humoral_immune1.40225801
36MP0003763_abnormal_thymus_physiology1.39355161
37MP0002837_dystrophic_cardiac_calcinosis1.38679449
38MP0003646_muscle_fatigue1.37229987
39MP0006292_abnormal_olfactory_placode1.36552796
40MP0002148_abnormal_hypersensitivity_rea1.35461818
41MP0002095_abnormal_skin_pigmentation1.34436102
42MP0010094_abnormal_chromosome_stability1.33907098
43MP0002138_abnormal_hepatobiliary_system1.29994782
44MP0004142_abnormal_muscle_tone1.28883700
45MP0002166_altered_tumor_susceptibility1.26695942
46MP0002653_abnormal_ependyma_morphology1.26020035
47MP0004043_abnormal_pH_regulation1.25356603
48MP0002735_abnormal_chemical_nociception1.25070044
49MP0009697_abnormal_copulation1.24637274
50MP0005253_abnormal_eye_physiology1.23257673
51MP0005389_reproductive_system_phenotype1.21887803
52MP0000685_abnormal_immune_system1.20624485
53MP0001984_abnormal_olfaction1.19437570
54MP0001486_abnormal_startle_reflex1.17673850
55MP0000427_abnormal_hair_cycle1.17637606
56MP0005084_abnormal_gallbladder_morpholo1.12811024
57MP0002420_abnormal_adaptive_immunity1.11414677
58MP0006276_abnormal_autonomic_nervous1.09189114
59MP0002723_abnormal_immune_serum1.09028042
60MP0001819_abnormal_immune_cell1.08617002
61MP0002006_tumorigenesis1.07082641
62MP0005025_abnormal_response_to1.05811993
63MP0005464_abnormal_platelet_physiology1.04581273
64MP0005266_abnormal_metabolism1.04565591
65MP0002452_abnormal_antigen_presenting1.04313066
66MP0009046_muscle_twitch1.03256381
67MP0009764_decreased_sensitivity_to1.02947225
68MP0009745_abnormal_behavioral_response1.02600428
69MP0005387_immune_system_phenotype1.01164210
70MP0001790_abnormal_immune_system1.01164210
71MP0002419_abnormal_innate_immunity1.00791822
72MP0001919_abnormal_reproductive_system1.00333150
73MP0005000_abnormal_immune_tolerance0.98504155
74MP0004885_abnormal_endolymph0.97881556
75MP0000689_abnormal_spleen_morphology0.96366517
76MP0002398_abnormal_bone_marrow0.96082992
77MP0000015_abnormal_ear_pigmentation0.94876557
78MP0000716_abnormal_immune_system0.92970792
79MP0003698_abnormal_male_reproductive0.91659785
80MP0002163_abnormal_gland_morphology0.91215290
81MP0006036_abnormal_mitochondrial_physio0.89837509
82MP0001929_abnormal_gametogenesis0.86037630
83MP0003724_increased_susceptibility_to0.85947116
84MP0008995_early_reproductive_senescence0.85381319
85MP0003136_yellow_coat_color0.84790609
86MP0002722_abnormal_immune_system0.84249316
87MP0001905_abnormal_dopamine_level0.82470678
88MP0001970_abnormal_pain_threshold0.80189934
89MP0002733_abnormal_thermal_nociception0.79486083
90MP0000465_gastrointestinal_hemorrhage0.78662067
91MP0010386_abnormal_urinary_bladder0.77661193
92MP0002272_abnormal_nervous_system0.75636515
93MP0003806_abnormal_nucleotide_metabolis0.75004377
94MP0003656_abnormal_erythrocyte_physiolo0.74042524
95MP0005379_endocrine/exocrine_gland_phen0.73785032
96MP0002693_abnormal_pancreas_physiology0.73391770
97MP0004742_abnormal_vestibular_system0.73254649
98MP0004924_abnormal_behavior0.73226337
99MP0005386_behavior/neurological_phenoty0.73226337
100MP0000631_abnormal_neuroendocrine_gland0.72717318

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of B cell number (HP:0010975)5.74944218
2B lymphocytopenia (HP:0010976)5.57951146
3Severe combined immunodeficiency (HP:0004430)4.88256977
4Thyroiditis (HP:0100646)4.66918202
5Hypoproteinemia (HP:0003075)4.28630095
6Hypoplasia of the thymus (HP:0000778)4.26049441
7Panhypogammaglobulinemia (HP:0003139)4.21930264
8Eosinophilia (HP:0001880)3.67943319
9Combined immunodeficiency (HP:0005387)3.60162321
10Congenital stationary night blindness (HP:0007642)3.39217431
11Pancreatic cysts (HP:0001737)3.37974109
12Abnormality of eosinophils (HP:0001879)3.25600080
13Granulocytopenia (HP:0001913)3.23135432
14Pancreatic fibrosis (HP:0100732)3.18062694
15Attenuation of retinal blood vessels (HP:0007843)3.15487365
16Agammaglobulinemia (HP:0004432)3.09249756
17Abnormal rod and cone electroretinograms (HP:0008323)2.91335193
18Abnormality of the renal cortex (HP:0011035)2.88924162
19Nephronophthisis (HP:0000090)2.87682963
20Elevated erythrocyte sedimentation rate (HP:0003565)2.86076013
21Absent rod-and cone-mediated responses on ERG (HP:0007688)2.85483023
22True hermaphroditism (HP:0010459)2.80763693
23Renal cortical cysts (HP:0000803)2.78967785
24T lymphocytopenia (HP:0005403)2.75968828
25Abnormality of the prostate (HP:0008775)2.74904608
26Abnormality of T cell number (HP:0011839)2.68677026
27Abnormality of the renal medulla (HP:0100957)2.59618892
28Medial flaring of the eyebrow (HP:0010747)2.52129097
29Abnormality of midbrain morphology (HP:0002418)2.51192623
30Molar tooth sign on MRI (HP:0002419)2.51192623
31IgG deficiency (HP:0004315)2.47349883
32Hepatocellular necrosis (HP:0001404)2.47027648
33Gaze-evoked nystagmus (HP:0000640)2.39730233
34Acute lymphatic leukemia (HP:0006721)2.39696160
35Thrombocytosis (HP:0001894)2.34491468
36Metaphyseal dysplasia (HP:0100255)2.33973158
37Stomach cancer (HP:0012126)2.31428716
38Hepatic necrosis (HP:0002605)2.29554538
39Chronic sinusitis (HP:0011109)2.24945675
40Mitochondrial inheritance (HP:0001427)2.23726726
41Decreased central vision (HP:0007663)2.20857094
42Recurrent fungal infections (HP:0002841)2.20737801
43Abnormality of dicarboxylic acid metabolism (HP:0010995)2.20306230
44Dicarboxylic aciduria (HP:0003215)2.20306230
45Leukocytosis (HP:0001974)2.18246807
46Chronic hepatic failure (HP:0100626)2.17627258
47Hypothermia (HP:0002045)2.16626922
48Constricted visual fields (HP:0001133)2.16176510
49Increased CSF lactate (HP:0002490)2.15057693
50Colon cancer (HP:0003003)2.13637404
51Methylmalonic aciduria (HP:0012120)2.12154087
52Type I transferrin isoform profile (HP:0003642)2.09030932
53Abnormal protein glycosylation (HP:0012346)2.08026681
54Abnormal glycosylation (HP:0012345)2.08026681
55Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.08026681
56Abnormal protein N-linked glycosylation (HP:0012347)2.08026681
57Hyperventilation (HP:0002883)2.04379413
58Dyschromatopsia (HP:0007641)2.03296535
59Decreased electroretinogram (ERG) amplitude (HP:0000654)2.00941329
60Abnormality of T cells (HP:0002843)2.00043952
61Progressive cerebellar ataxia (HP:0002073)1.98101482
62Abolished electroretinogram (ERG) (HP:0000550)1.97285576
63Cystic liver disease (HP:0006706)1.95304291
64Methylmalonic acidemia (HP:0002912)1.92693281
65Ketosis (HP:0001946)1.88361379
66Tubulointerstitial nephritis (HP:0001970)1.86495563
67Stomatitis (HP:0010280)1.86316265
68Febrile seizures (HP:0002373)1.85689007
69Reduced antithrombin III activity (HP:0001976)1.85584649
70Aplasia/Hypoplasia of the thymus (HP:0010515)1.82526244
71Abnormality of macular pigmentation (HP:0008002)1.82391103
72Abnormality of lateral ventricle (HP:0030047)1.81442226
73Meningitis (HP:0001287)1.78402186
74Bony spicule pigmentary retinopathy (HP:0007737)1.78318372
75Central scotoma (HP:0000603)1.77694913
76Acute necrotizing encephalopathy (HP:0006965)1.77388273
77Prostate neoplasm (HP:0100787)1.76621829
78Erythroderma (HP:0001019)1.75213122
79Abnormality of male internal genitalia (HP:0000022)1.74202010
80Neutropenia (HP:0001875)1.73683977
81Albinism (HP:0001022)1.73466407
82Recurrent cutaneous fungal infections (HP:0011370)1.73106147
83Chronic mucocutaneous candidiasis (HP:0002728)1.73106147
84Progressive macrocephaly (HP:0004481)1.73023629
85Abnormal drinking behavior (HP:0030082)1.72310626
86Polydipsia (HP:0001959)1.72310626
87Microvesicular hepatic steatosis (HP:0001414)1.72302404
88Progressive microcephaly (HP:0000253)1.70478580
89Polyuria (HP:0000103)1.70090824
90Type II lissencephaly (HP:0007260)1.69765227
91Aplasia/Hypoplasia of the tongue (HP:0010295)1.69470054
92Chronic otitis media (HP:0000389)1.69009004
93Macular degeneration (HP:0000608)1.68498424
94Bile duct proliferation (HP:0001408)1.68362484
95Abnormal biliary tract physiology (HP:0012439)1.68362484
96Abnormal respiratory motile cilium morphology (HP:0005938)1.67952477
97Abnormal respiratory epithelium morphology (HP:0012253)1.67952477
98Protruding tongue (HP:0010808)1.67539209
99Aplasia/Hypoplasia of the tibia (HP:0005772)1.67481516
100Aplasia/Hypoplasia of the uvula (HP:0010293)1.67218380

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.27894663
2MAP4K24.29078482
3TXK2.81137536
4BCKDK2.69900302
5NUAK12.61546995
6ZAK2.59612820
7PINK12.49343613
8TAOK32.43675363
9ADRBK22.42537910
10KIT2.26244190
11PIK3CG2.18094465
12BMPR1B2.05546714
13FLT32.03715810
14TNK22.00453629
15VRK21.91917751
16WNK31.88030545
17GRK11.85937741
18TEC1.81590351
19EIF2AK31.65091280
20NLK1.55290501
21TLK11.49512184
22MAPK131.48648191
23MAP4K11.46412605
24INSRR1.37014968
25STK38L1.28445371
26TRIM281.27132240
27IKBKB1.24451087
28VRK11.18517568
29SYK1.16728032
30BMPR21.16206423
31TNIK1.12935968
32BTK1.06922574
33KDR1.06335747
34FES1.03173928
35ADRBK11.02919832
36CSNK1A1L0.97869360
37CSNK1G30.97388449
38PRKCE0.96359493
39MUSK0.95315449
40DYRK20.84065388
41PRKCQ0.83029026
42RPS6KA50.82633101
43CSNK1G20.79158413
44MKNK10.77235837
45OXSR10.76633580
46ITK0.75357727
47CSNK1G10.74574940
48DAPK20.73726208
49MAPKAPK50.73322185
50MAP3K120.72117158
51MAP2K20.69638024
52PLK40.69076205
53LYN0.69006401
54PLK20.67233514
55PIK3CA0.67216007
56MARK30.64706414
57GRK60.63657423
58DYRK30.63633018
59CSF1R0.60285261
60ATR0.59524909
61TGFBR10.59069880
62PTK2B0.58950732
63PIM20.58108378
64RPS6KA40.57971332
65IKBKE0.56975935
66GRK50.55231347
67GRK70.51055732
68MAP3K70.46154660
69ACVR1B0.45543893
70CDK30.44473422
71LCK0.44233621
72TESK20.42937921
73PAK30.42776065
74MAP2K70.41798402
75CSNK1A10.40554336
76CHEK20.39481581
77FER0.39380475
78ABL20.38119321
79ABL10.38103228
80HCK0.36380196
81CASK0.35659607
82ATM0.35653985
83CAMK10.34949964
84TBK10.34635517
85RPS6KA60.34251490
86PIM10.33747583
87HIPK20.33685863
88MAPKAPK30.32940198
89CAMKK20.31731119
90IGF1R0.31639809
91PRKCG0.30568526
92DYRK1A0.30220870
93MKNK20.30150946
94CDK80.29615019
95MAP3K110.29609523
96PRKCI0.29363515
97SRPK10.29202150
98CSNK1D0.27951790
99PRKACA0.27899343
100CDC70.27569222

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047443.39743714
2Non-homologous end-joining_Homo sapiens_hsa034503.14652346
3Primary immunodeficiency_Homo sapiens_hsa053403.04425151
4Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.92984187
5Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.87290732
6Caffeine metabolism_Homo sapiens_hsa002322.57100361
7Homologous recombination_Homo sapiens_hsa034402.15590197
8Asthma_Homo sapiens_hsa053102.13730548
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.10161518
10Butanoate metabolism_Homo sapiens_hsa006502.09061429
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.08406640
12Linoleic acid metabolism_Homo sapiens_hsa005911.99351961
13Fanconi anemia pathway_Homo sapiens_hsa034601.96041047
14Olfactory transduction_Homo sapiens_hsa047401.70550477
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.70547179
16Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.66608497
17Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.66487840
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.61687350
19RNA polymerase_Homo sapiens_hsa030201.59485081
20Tryptophan metabolism_Homo sapiens_hsa003801.50775203
21Oxidative phosphorylation_Homo sapiens_hsa001901.48014216
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.46110200
23Nitrogen metabolism_Homo sapiens_hsa009101.44841537
24Protein export_Homo sapiens_hsa030601.36292133
25Allograft rejection_Homo sapiens_hsa053301.36135465
26Steroid hormone biosynthesis_Homo sapiens_hsa001401.34587469
27Base excision repair_Homo sapiens_hsa034101.32503178
28RNA degradation_Homo sapiens_hsa030181.27665617
29Graft-versus-host disease_Homo sapiens_hsa053321.26932988
30Chemical carcinogenesis_Homo sapiens_hsa052041.26918091
31Ether lipid metabolism_Homo sapiens_hsa005651.26658957
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.26510727
33Type I diabetes mellitus_Homo sapiens_hsa049401.23569995
34Autoimmune thyroid disease_Homo sapiens_hsa053201.22887958
35Propanoate metabolism_Homo sapiens_hsa006401.22327838
36Peroxisome_Homo sapiens_hsa041461.21367503
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.19035800
38Hematopoietic cell lineage_Homo sapiens_hsa046401.17386392
39Parkinsons disease_Homo sapiens_hsa050121.16318752
40Regulation of autophagy_Homo sapiens_hsa041401.14205969
41Arachidonic acid metabolism_Homo sapiens_hsa005901.13841042
42SNARE interactions in vesicular transport_Homo sapiens_hsa041301.13421394
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.12155356
44Selenocompound metabolism_Homo sapiens_hsa004501.10313388
45Salivary secretion_Homo sapiens_hsa049701.07223370
46Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.05078032
47Basal transcription factors_Homo sapiens_hsa030220.99804873
48Nicotine addiction_Homo sapiens_hsa050330.98005423
49Retinol metabolism_Homo sapiens_hsa008300.97701829
50Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.96773457
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96509495
52Purine metabolism_Homo sapiens_hsa002300.94605770
53ABC transporters_Homo sapiens_hsa020100.91315626
54beta-Alanine metabolism_Homo sapiens_hsa004100.90779652
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.89511546
56Pyrimidine metabolism_Homo sapiens_hsa002400.86943780
57Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.86769979
58Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.85811273
59Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81552068
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80093900
61Antigen processing and presentation_Homo sapiens_hsa046120.78507959
62DNA replication_Homo sapiens_hsa030300.78470227
63Taste transduction_Homo sapiens_hsa047420.77765935
64Systemic lupus erythematosus_Homo sapiens_hsa053220.74297465
65Huntingtons disease_Homo sapiens_hsa050160.70847154
66Glycerolipid metabolism_Homo sapiens_hsa005610.69084356
67Circadian entrainment_Homo sapiens_hsa047130.68362468
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.66401625
69Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64048149
70Metabolic pathways_Homo sapiens_hsa011000.63805081
71RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.62142966
72Pentose and glucuronate interconversions_Homo sapiens_hsa000400.59021411
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.58750987
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.57989060
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57772271
76Renin-angiotensin system_Homo sapiens_hsa046140.56915458
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56394454
78Alzheimers disease_Homo sapiens_hsa050100.55628017
79Calcium signaling pathway_Homo sapiens_hsa040200.54104987
80Rheumatoid arthritis_Homo sapiens_hsa053230.52362970
81Morphine addiction_Homo sapiens_hsa050320.49638611
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.47782346
83Fatty acid elongation_Homo sapiens_hsa000620.47215388
84Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.46827923
85Mismatch repair_Homo sapiens_hsa034300.46104744
86Ovarian steroidogenesis_Homo sapiens_hsa049130.45329349
87Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.44952521
88NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43690245
89Nucleotide excision repair_Homo sapiens_hsa034200.43441885
90Serotonergic synapse_Homo sapiens_hsa047260.43079411
91N-Glycan biosynthesis_Homo sapiens_hsa005100.42615826
92Staphylococcus aureus infection_Homo sapiens_hsa051500.42279601
93Platelet activation_Homo sapiens_hsa046110.37724019
94Sphingolipid metabolism_Homo sapiens_hsa006000.36029856
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.33942392
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.33671050
97Glutathione metabolism_Homo sapiens_hsa004800.32404802
98Dorso-ventral axis formation_Homo sapiens_hsa043200.32032039
99Circadian rhythm_Homo sapiens_hsa047100.31236562
100Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.30190817

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »