ANO8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.29204910
2locomotory exploration behavior (GO:0035641)5.24560206
3layer formation in cerebral cortex (GO:0021819)4.90654329
4regulation of short-term neuronal synaptic plasticity (GO:0048172)4.77006879
5pyrimidine nucleobase catabolic process (GO:0006208)4.71208207
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.54797413
7regulation of synapse structural plasticity (GO:0051823)4.33756653
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.28532651
9establishment of mitochondrion localization (GO:0051654)4.21013605
10synaptic vesicle docking involved in exocytosis (GO:0016081)4.11660388
11cell-cell junction maintenance (GO:0045217)4.11544944
12vocalization behavior (GO:0071625)4.05526510
13establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.03666136
14mitochondrion transport along microtubule (GO:0047497)4.03666136
15dendritic spine morphogenesis (GO:0060997)4.02878898
16regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.97580577
17presynaptic membrane organization (GO:0097090)3.88011052
18presynaptic membrane assembly (GO:0097105)3.82029771
19semaphorin-plexin signaling pathway (GO:0071526)3.78848226
20sodium ion export (GO:0071436)3.74663430
21central nervous system myelination (GO:0022010)3.72515458
22axon ensheathment in central nervous system (GO:0032291)3.72515458
23regulation of glutamate receptor signaling pathway (GO:1900449)3.71911278
24glutamate secretion (GO:0014047)3.71230418
25regulation of synaptic vesicle exocytosis (GO:2000300)3.69159533
26cytoskeletal anchoring at plasma membrane (GO:0007016)3.67742087
27exploration behavior (GO:0035640)3.64640227
28activation of protein kinase A activity (GO:0034199)3.61566605
29cell migration in hindbrain (GO:0021535)3.60538800
30dendrite morphogenesis (GO:0048813)3.58534163
31nucleobase catabolic process (GO:0046113)3.58114146
32establishment of nucleus localization (GO:0040023)3.57939261
33synaptic vesicle exocytosis (GO:0016079)3.49624132
34cerebellar Purkinje cell layer development (GO:0021680)3.45557434
35plasma membrane repair (GO:0001778)3.44537878
36neuromuscular process controlling balance (GO:0050885)3.41735756
37cell communication by electrical coupling (GO:0010644)3.39098709
38cell junction maintenance (GO:0034331)3.36818725
39regulation of neuronal synaptic plasticity (GO:0048168)3.34965892
40positive regulation of synapse maturation (GO:0090129)3.34252885
41protein localization to synapse (GO:0035418)3.27420989
42camera-type eye morphogenesis (GO:0048593)3.25892670
43cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.25593522
44regulation of long-term neuronal synaptic plasticity (GO:0048169)3.25526242
45neurotransmitter secretion (GO:0007269)3.25189385
46proline transport (GO:0015824)3.24097404
47regulation of synapse maturation (GO:0090128)3.20577634
48regulation of ARF protein signal transduction (GO:0032012)3.19831948
49planar cell polarity pathway involved in neural tube closure (GO:0090179)3.18642890
50cellular potassium ion homeostasis (GO:0030007)3.17115139
51regulation of synaptic vesicle transport (GO:1902803)3.15252701
52adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.12701955
53positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.10159686
54axonal fasciculation (GO:0007413)3.09728219
55ionotropic glutamate receptor signaling pathway (GO:0035235)3.07193520
56neuron projection extension (GO:1990138)3.06790498
57regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.03873850
58membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.03172149
59prepulse inhibition (GO:0060134)3.01784766
60G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.99952586
61regulation of dendritic spine morphogenesis (GO:0061001)2.95365884
62regulation of ARF GTPase activity (GO:0032312)2.94680759
63negative regulation of axonogenesis (GO:0050771)2.92723309
64neuron recognition (GO:0008038)2.90965652
65gamma-aminobutyric acid transport (GO:0015812)2.89253940
66glycine transport (GO:0015816)2.87680278
67clathrin coat assembly (GO:0048268)2.86891069
68spinal cord development (GO:0021510)2.84998000
69negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.83098880
70neuron cell-cell adhesion (GO:0007158)2.81290621
71regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.80389749
72regulation of axon extension involved in axon guidance (GO:0048841)2.78462894
73cerebellar Purkinje cell differentiation (GO:0021702)2.78383629
74neuronal action potential propagation (GO:0019227)2.77801866
75regulation of axonogenesis (GO:0050770)2.77116872
76dendritic spine organization (GO:0097061)2.76466214
77positive regulation of synapse assembly (GO:0051965)2.76325433
78collecting duct development (GO:0072044)2.74882871
79auditory behavior (GO:0031223)2.74045141
80neuronal ion channel clustering (GO:0045161)2.73921629
81negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.73398755
82neurotransmitter-gated ion channel clustering (GO:0072578)2.73325825
83mechanosensory behavior (GO:0007638)2.72835247
84synapse assembly (GO:0007416)2.69992300
85cellular response to catecholamine stimulus (GO:0071870)2.69822825
86cellular response to monoamine stimulus (GO:0071868)2.69822825
87vesicle transport along microtubule (GO:0047496)2.69013408
88neural tube development (GO:0021915)2.66936194
89positive regulation of axon extension (GO:0045773)2.64753668
90innervation (GO:0060384)2.64445827
91positive regulation of synaptic transmission, GABAergic (GO:0032230)2.64278608
92regulation of excitatory postsynaptic membrane potential (GO:0060079)2.64250838
93positive regulation of fibroblast migration (GO:0010763)2.64234499
94long-term memory (GO:0007616)2.63932841
95dopamine receptor signaling pathway (GO:0007212)2.62563730
96transmission of nerve impulse (GO:0019226)2.62389541
97mannose metabolic process (GO:0006013)2.61997886
98cell differentiation in hindbrain (GO:0021533)2.61980274
99negative regulation of catenin import into nucleus (GO:0035414)2.61345853
100nerve growth factor signaling pathway (GO:0038180)2.59981139
101negative regulation of cell size (GO:0045792)2.59788339
102synaptic transmission, glutamatergic (GO:0035249)2.59206147
103central nervous system projection neuron axonogenesis (GO:0021952)2.58688466
104axon extension (GO:0048675)2.58286604
105positive regulation of membrane potential (GO:0045838)2.58249999
106membrane depolarization during action potential (GO:0086010)2.56618038
107axon extension involved in axon guidance (GO:0048846)2.56028947
108neuron projection extension involved in neuron projection guidance (GO:1902284)2.56028947
109respiratory system process (GO:0003016)2.55722872
110organelle transport along microtubule (GO:0072384)2.55628738
111response to parathyroid hormone (GO:0071107)2.55451834
112stress fiber assembly (GO:0043149)2.55277112
113glutamate receptor signaling pathway (GO:0007215)2.55250863
114convergent extension (GO:0060026)2.54973853
115regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.54493791
116regulation of respiratory system process (GO:0044065)2.54319459
117potassium ion import (GO:0010107)2.53183361
118regulation of axon guidance (GO:1902667)2.53141814
119cell communication involved in cardiac conduction (GO:0086065)2.52693902
120positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.52679681
121peptidyl-tyrosine autophosphorylation (GO:0038083)2.51868210
122regulation of synaptic plasticity (GO:0048167)2.51182595
123regulation of clathrin-mediated endocytosis (GO:2000369)2.50617748
124regulation of vesicle fusion (GO:0031338)2.50164853
125regulation of postsynaptic membrane potential (GO:0060078)2.49254181
126ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.49158973
127positive regulation of dendritic spine development (GO:0060999)2.48323658
128axon cargo transport (GO:0008088)2.47505811
129potassium ion homeostasis (GO:0055075)2.46524294
130postsynaptic membrane organization (GO:0001941)2.45647017
131glial cell proliferation (GO:0014009)2.45135068
132regulation of dendritic spine development (GO:0060998)2.45002102
133alanine transport (GO:0032328)2.44250536
134response to auditory stimulus (GO:0010996)2.43665301
135suckling behavior (GO:0001967)2.43111334
136positive regulation of dendrite development (GO:1900006)2.40486271
137peptidyl-lysine dimethylation (GO:0018027)2.40292317
138negative regulation of microtubule polymerization (GO:0031115)2.39572882
139neuromuscular process (GO:0050905)2.38952807
140regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.38359182
141cerebellar granule cell differentiation (GO:0021707)2.37937279
142regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.37670408
143protein localization to endosome (GO:0036010)2.36990925
144regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.36190943
145synaptic vesicle endocytosis (GO:0048488)2.35593553

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.90169885
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.44903971
3EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.14818386
4DROSHA_22980978_ChIP-Seq_HELA_Human2.66537736
5RARB_27405468_Chip-Seq_BRAIN_Mouse2.57998597
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.42171355
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.42171355
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.36095646
9MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.35691495
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.30747643
11ZFP281_18757296_ChIP-ChIP_E14_Mouse2.26370588
12KDM2B_26808549_Chip-Seq_SUP-B15_Human2.24166127
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.22524427
14KDM2B_26808549_Chip-Seq_K562_Human2.22064215
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.19992481
16WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.17493939
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12386061
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.06027397
19* EZH2_27294783_Chip-Seq_ESCs_Mouse2.01250117
20KDM2B_26808549_Chip-Seq_DND41_Human1.99558919
21RNF2_27304074_Chip-Seq_ESCs_Mouse1.98167278
22* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.96761009
23EZH2_27304074_Chip-Seq_ESCs_Mouse1.96378434
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.93494701
25NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.90653119
26SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.88087035
27ZFP281_27345836_Chip-Seq_ESCs_Mouse1.87586422
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.86832791
29ERG_21242973_ChIP-ChIP_JURKAT_Human1.85624757
30REST_21632747_ChIP-Seq_MESCs_Mouse1.83517536
31STAT6_21828071_ChIP-Seq_BEAS2B_Human1.83272236
32EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.82854280
33TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.81955975
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.76025017
35DNAJC2_21179169_ChIP-ChIP_NT2_Human1.75221701
36KDM2B_26808549_Chip-Seq_JURKAT_Human1.72917220
37LXR_22292898_ChIP-Seq_THP-1_Human1.72827021
38CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.71756166
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.68360281
40TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.68249453
41EED_16625203_ChIP-ChIP_MESCs_Mouse1.62450579
42EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.62326865
43P68_20966046_ChIP-Seq_HELA_Human1.62275761
44DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.62086866
45REST_18959480_ChIP-ChIP_MESCs_Mouse1.61982209
46KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.52425285
47TP63_17297297_ChIP-ChIP_HaCaT_Human1.47691985
48SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.47668723
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.45425876
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.44281072
51GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.44032317
52NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.43888930
53WT1_25993318_ChIP-Seq_PODOCYTE_Human1.42056695
54* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.41631044
55SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.39585964
56ZNF263_19887448_ChIP-Seq_K562_Human1.38907203
57SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.33669474
58TET1_21451524_ChIP-Seq_MESCs_Mouse1.33650437
59ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.33184311
60TCF7_22412390_ChIP-Seq_EML_Mouse1.33139283
61MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.33060062
62P300_27058665_Chip-Seq_ZR-75-30cells_Human1.30097859
63RING1B_27294783_Chip-Seq_NPCs_Mouse1.29557671
64SA1_27219007_Chip-Seq_ERYTHROID_Human1.29537645
65OCT4_19829295_ChIP-Seq_ESCs_Human1.23081201
66VDR_21846776_ChIP-Seq_THP-1_Human1.23036097
67CREB1_26743006_Chip-Seq_LNCaP_Human1.21863020
68VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.21372158
69AR_21572438_ChIP-Seq_LNCaP_Human1.21069308
70CBX2_27304074_Chip-Seq_ESCs_Mouse1.20097121
71TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20095895
72OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.18550504
73ESR2_21235772_ChIP-Seq_MCF-7_Human1.15864279
74CTCF_27219007_Chip-Seq_Bcells_Human1.15164738
75RARG_19884340_ChIP-ChIP_MEFs_Mouse1.14324176
76ELK3_25401928_ChIP-Seq_HUVEC_Human1.14067782
77RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.12766457
78ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.12047710
79TRIM28_21343339_ChIP-Seq_HEK293_Human1.11330876
80SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10479332
81CTCF_27219007_Chip-Seq_ERYTHROID_Human1.09685459
82UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.09247689
83ZNF274_21170338_ChIP-Seq_K562_Hela1.08896707
84AR_19668381_ChIP-Seq_PC3_Human1.08584793
85TET1_21490601_ChIP-Seq_MESCs_Mouse1.06483310
86TP53_20018659_ChIP-ChIP_R1E_Mouse1.06370974
87RACK7_27058665_Chip-Seq_MCF-7_Human1.06126540
88CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.06093522
89TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.05705377
90GBX2_23144817_ChIP-Seq_PC3_Human1.02957422
91SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02334918
92SMC4_20622854_ChIP-Seq_HELA_Human1.01516971
93* SOX3_22085726_ChIP-Seq_NPCs_Mouse1.01351045
94ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01134337
95MYC_22102868_ChIP-Seq_BL_Human1.00252770
96POU5F1_16518401_ChIP-PET_MESCs_Mouse0.99452149
97NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.98019684
98TP63_22573176_ChIP-Seq_HFKS_Human0.97611781
99SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.97223523
100TP53_22127205_ChIP-Seq_IMR90_Human0.96725851
101* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.96644038
102SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.96247217
103PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.95319299
104NR3C1_23031785_ChIP-Seq_PC12_Mouse0.93660330
105SOX2_21211035_ChIP-Seq_LN229_Gbm0.93383552
106AHR_22903824_ChIP-Seq_MCF-7_Human0.92860147
107KLF4_19829295_ChIP-Seq_ESCs_Human0.92608265
108MYC_27129775_Chip-Seq_CORNEA_Mouse0.91792636
109ISL1_27105846_Chip-Seq_CPCs_Mouse0.90592346
110SA1_27219007_Chip-Seq_Bcells_Human0.90555379
111* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89919702
112ELF1_20517297_ChIP-Seq_JURKAT_Human0.89572601
113ESR1_20079471_ChIP-ChIP_T-47D_Human0.89315622
114PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.89021187
115CTNNB1_20460455_ChIP-Seq_HCT116_Human0.88223330
116TP53_16413492_ChIP-PET_HCT116_Human0.87001417
117YAP1_20516196_ChIP-Seq_MESCs_Mouse0.86241431
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.86230046
119RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.85983537
120* TP53_23651856_ChIP-Seq_MEFs_Mouse0.85917664
121RUNX1_27514584_Chip-Seq_MCF-7_Human0.85535486
122ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.85521828
123RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.85482245
124EP300_21415370_ChIP-Seq_HL-1_Mouse0.84250042
125CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.83797749

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.15449773
2MP0003635_abnormal_synaptic_transmissio3.31854748
3MP0004270_analgesia2.97252097
4MP0009780_abnormal_chondrocyte_physiolo2.78767821
5MP0004858_abnormal_nervous_system2.70777944
6MP0003283_abnormal_digestive_organ2.56144215
7MP0002063_abnormal_learning/memory/cond2.53814025
8MP0003123_paternal_imprinting2.45011174
9MP0000751_myopathy2.39676864
10MP0005423_abnormal_somatic_nervous2.32838066
11MP0003705_abnormal_hypodermis_morpholog2.28718754
12MP0009745_abnormal_behavioral_response2.26632663
13MP0003880_abnormal_central_pattern2.19397983
14MP0002909_abnormal_adrenal_gland2.16594159
15MP0002064_seizures2.10573936
16MP0005623_abnormal_meninges_morphology2.07104122
17MP0008961_abnormal_basal_metabolism2.05368950
18MP0002822_catalepsy2.04028241
19MP0002249_abnormal_larynx_morphology1.99053823
20MP0000569_abnormal_digit_pigmentation1.94535042
21MP0001502_abnormal_circadian_rhythm1.92061121
22MP0003329_amyloid_beta_deposits1.89506770
23MP0009046_muscle_twitch1.88267586
24MP0008569_lethality_at_weaning1.87877742
25MP0004811_abnormal_neuron_physiology1.85402773
26MP0000778_abnormal_nervous_system1.83865979
27MP0001188_hyperpigmentation1.78142741
28MP0000566_synostosis1.76953875
29MP0002734_abnormal_mechanical_nocicepti1.76419055
30MP0002572_abnormal_emotion/affect_behav1.74228499
31MP0001968_abnormal_touch/_nociception1.73431870
32MP0005409_darkened_coat_color1.66114572
33MP0006276_abnormal_autonomic_nervous1.65536544
34MP0003121_genomic_imprinting1.62936252
35MP0004130_abnormal_muscle_cell1.61793488
36MP0000955_abnormal_spinal_cord1.60301595
37MP0004233_abnormal_muscle_weight1.58422840
38MP0005076_abnormal_cell_differentiation1.58281090
39MP0002184_abnormal_innervation1.55588715
40MP0001486_abnormal_startle_reflex1.50537426
41MP0006292_abnormal_olfactory_placode1.50069050
42MP0002234_abnormal_pharynx_morphology1.47455547
43MP0002733_abnormal_thermal_nociception1.45647011
44MP0005394_taste/olfaction_phenotype1.44443371
45MP0005499_abnormal_olfactory_system1.44443371
46MP0001299_abnormal_eye_distance/1.44215718
47MP0010234_abnormal_vibrissa_follicle1.44106530
48MP0009379_abnormal_foot_pigmentation1.43882307
49MP0004145_abnormal_muscle_electrophysio1.43138460
50MP0001984_abnormal_olfaction1.40096672
51MP0002272_abnormal_nervous_system1.38679713
52MP0000013_abnormal_adipose_tissue1.38023133
53MP0005377_hearing/vestibular/ear_phenot1.33938549
54MP0003878_abnormal_ear_physiology1.33938549
55MP0008438_abnormal_cutaneous_collagen1.32499944
56MP0004885_abnormal_endolymph1.30273700
57MP0001348_abnormal_lacrimal_gland1.29851010
58MP0001440_abnormal_grooming_behavior1.26332818
59MP0003942_abnormal_urinary_system1.25361628
60MP0001970_abnormal_pain_threshold1.24871905
61MP0004133_heterotaxia1.23731950
62MP0000579_abnormal_nail_morphology1.23421496
63MP0002557_abnormal_social/conspecific_i1.22105763
64MP0003045_fibrosis1.22037589
65MP0000747_muscle_weakness1.20302949
66MP0002067_abnormal_sensory_capabilities1.19933898
67MP0002882_abnormal_neuron_morphology1.19356933
68MP0004510_myositis1.17876325
69MP0004087_abnormal_muscle_fiber1.17670622
70MP0002735_abnormal_chemical_nociception1.16209985
71MP0000049_abnormal_middle_ear1.16146978
72MP0002752_abnormal_somatic_nervous1.15183707
73MP0002089_abnormal_postnatal_growth/wei1.15114207
74MP0000003_abnormal_adipose_tissue1.14889794
75MP0004924_abnormal_behavior1.14798017
76MP0005386_behavior/neurological_phenoty1.14798017
77MP0001501_abnormal_sleep_pattern1.13030135
78MP0003303_peritoneal_inflammation1.12567632
79MP0003136_yellow_coat_color1.12475143
80MP0003938_abnormal_ear_development1.11682288
81MP0002066_abnormal_motor_capabilities/c1.11155558
82MP0000537_abnormal_urethra_morphology1.10513382
83MP0000733_abnormal_muscle_development1.09871179
84MP0002736_abnormal_nociception_after1.09378390
85MP0000026_abnormal_inner_ear1.08590934
86MP0002152_abnormal_brain_morphology1.08525168
87MP0002116_abnormal_craniofacial_bone1.07162431
88MP0000631_abnormal_neuroendocrine_gland1.07144608
89MP0008789_abnormal_olfactory_epithelium1.06137550
90MP0003172_abnormal_lysosome_physiology1.05915737
91MP0003633_abnormal_nervous_system1.05867886
92MP0003690_abnormal_glial_cell1.05603968
93MP0000759_abnormal_skeletal_muscle1.02699419
94MP0002837_dystrophic_cardiac_calcinosis0.99005443
95MP0003075_altered_response_to0.98658979
96MP0002653_abnormal_ependyma_morphology0.98582122
97MP0003787_abnormal_imprinting0.97934061
98MP0000678_abnormal_parathyroid_gland0.97030065
99MP0000534_abnormal_ureter_morphology0.95930122
100MP0002877_abnormal_melanocyte_morpholog0.95555514
101MP0003634_abnormal_glial_cell0.95490834
102MP0003879_abnormal_hair_cell0.95198562
103MP0001849_ear_inflammation0.95016714
104MP0010030_abnormal_orbit_morphology0.94676618
105MP0003137_abnormal_impulse_conducting0.94328897
106MP0009384_cardiac_valve_regurgitation0.90749449
107MP0004185_abnormal_adipocyte_glucose0.89872547
108MP0005375_adipose_tissue_phenotype0.89741016
109MP0004142_abnormal_muscle_tone0.89492783
110MP0003091_abnormal_cell_migration0.86056866
111MP0005275_abnormal_skin_tensile0.86026725
112MP0005187_abnormal_penis_morphology0.85969868
113MP0004084_abnormal_cardiac_muscle0.85897446
114MP0002638_abnormal_pupillary_reflex0.85868781
115MP0003300_gastrointestinal_ulcer0.85115971
116MP0001485_abnormal_pinna_reflex0.85031081
117MP0004085_abnormal_heartbeat0.84306680
118MP0001963_abnormal_hearing_physiology0.84121252
119MP0004742_abnormal_vestibular_system0.83499459
120MP0002896_abnormal_bone_mineralization0.83441935
121MP0005167_abnormal_blood-brain_barrier0.83344500
122MP0002081_perinatal_lethality0.82608503
123MP0005257_abnormal_intraocular_pressure0.82157569
124MP0001177_atelectasis0.81892536
125MP0003631_nervous_system_phenotype0.81081904
126MP0002932_abnormal_joint_morphology0.80154737
127MP0003861_abnormal_nervous_system0.79594001
128MP0000604_amyloidosis0.78791372
129MP0005670_abnormal_white_adipose0.78349441
130MP0002269_muscular_atrophy0.78200451
131MP0002106_abnormal_muscle_physiology0.77471316
132MP0000749_muscle_degeneration0.77036716
133MP0003385_abnormal_body_wall0.76916891
134MP0001943_abnormal_respiration0.76629403
135MP0002069_abnormal_eating/drinking_beha0.75236921
136MP0001958_emphysema0.75089546
137MP0000428_abnormal_craniofacial_morphol0.74855696
138MP0002697_abnormal_eye_size0.73326266
139MP0008874_decreased_physiological_sensi0.72087936
140MP0003948_abnormal_gas_homeostasis0.71866559
141MP0003119_abnormal_digestive_system0.71499473
142MP0005620_abnormal_muscle_contractility0.69674555
143MP0003122_maternal_imprinting0.69516825
144MP0005369_muscle_phenotype0.68214127
145MP0004215_abnormal_myocardial_fiber0.67412111

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)3.96127623
2Hyperacusis (HP:0010780)3.42483515
3Sleep apnea (HP:0010535)3.32749624
4Visual hallucinations (HP:0002367)3.11847637
5Insomnia (HP:0100785)3.09121467
6Focal seizures (HP:0007359)3.03776392
7Shallow orbits (HP:0000586)3.03680175
8Supranuclear gaze palsy (HP:0000605)3.01685230
9Action tremor (HP:0002345)2.96599585
10Abnormality of the lower motor neuron (HP:0002366)2.93436427
11Cerebral aneurysm (HP:0004944)2.89848742
12Focal motor seizures (HP:0011153)2.75900040
13Ankle clonus (HP:0011448)2.73625838
14Elfin facies (HP:0004428)2.73399033
15Pointed chin (HP:0000307)2.73200882
16Abnormality of the aortic arch (HP:0012303)2.72628536
17Difficulty running (HP:0009046)2.68936265
18Lower limb amyotrophy (HP:0007210)2.61525662
19Partial duplication of thumb phalanx (HP:0009944)2.60435111
20Hyperthyroidism (HP:0000836)2.56000895
21Insidious onset (HP:0003587)2.54532366
22Termporal pattern (HP:0011008)2.54532366
23Vitreoretinal degeneration (HP:0000655)2.51636174
24Distal upper limb amyotrophy (HP:0007149)2.50921566
25Upper limb amyotrophy (HP:0009129)2.50921566
26Bowel diverticulosis (HP:0005222)2.45853660
27Overriding aorta (HP:0002623)2.42735481
28Renovascular hypertension (HP:0100817)2.41720605
29Macroorchidism (HP:0000053)2.41004489
30Depression (HP:0000716)2.40473072
31Increased variability in muscle fiber diameter (HP:0003557)2.40021767
32Papilledema (HP:0001085)2.36790960
33Urinary urgency (HP:0000012)2.35434214
34Bladder diverticulum (HP:0000015)2.34102642
35Poor eye contact (HP:0000817)2.32455539
36Impaired social interactions (HP:0000735)2.32202427
37Abnormal social behavior (HP:0012433)2.32202427
38Broad face (HP:0000283)2.29985842
39Hypercortisolism (HP:0001578)2.28872131
40Megalencephaly (HP:0001355)2.28454843
41Dysmetric saccades (HP:0000641)2.27859139
42Impaired vibration sensation in the lower limbs (HP:0002166)2.27679726
43Mitral regurgitation (HP:0001653)2.25343021
44Bundle branch block (HP:0011710)2.25275840
45Achilles tendon contracture (HP:0001771)2.25236091
46Enlarged penis (HP:0000040)2.24995073
47Broad metatarsal (HP:0001783)2.22420372
48Hemiplegia (HP:0002301)2.22090636
49Thin bony cortex (HP:0002753)2.21891826
50Partial duplication of the phalanx of hand (HP:0009999)2.20688516
51Urinary bladder sphincter dysfunction (HP:0002839)2.19088541
52Genetic anticipation (HP:0003743)2.17435614
53Deep palmar crease (HP:0006191)2.17121500
54Abnormal eating behavior (HP:0100738)2.17091237
55Renal duplication (HP:0000075)2.13151329
56Abnormality of binocular vision (HP:0011514)2.13017914
57Diplopia (HP:0000651)2.13017914
58Ventricular fibrillation (HP:0001663)2.12816599
59Spinal canal stenosis (HP:0003416)2.12726192
60Anomalous pulmonary venous return (HP:0010772)2.11421711
61Cerebral inclusion bodies (HP:0100314)2.11410009
62Rib fusion (HP:0000902)2.11253403
63Torticollis (HP:0000473)2.10318609
64Protrusio acetabuli (HP:0003179)2.10289540
65Mutism (HP:0002300)2.10031990
66Aplasia involving bones of the upper limbs (HP:0009823)2.07344237
67Aplasia of the phalanges of the hand (HP:0009802)2.07344237
68Aplasia involving bones of the extremities (HP:0009825)2.07344237
69Turricephaly (HP:0000262)2.07337962
70Flat cornea (HP:0007720)2.06122263
71Abnormality of skeletal muscle fiber size (HP:0012084)2.02874560
72Ankyloglossia (HP:0010296)2.01231500
73Shawl scrotum (HP:0000049)2.00619090
74Limb dystonia (HP:0002451)2.00103835
75Hypoventilation (HP:0002791)1.99614461
76Difficulty climbing stairs (HP:0003551)1.98363034
77Polyphagia (HP:0002591)1.97347087
78Abnormality of the Achilles tendon (HP:0005109)1.96808810
79Type 1 muscle fiber predominance (HP:0003803)1.96415504
80Abnormality of the 4th metacarpal (HP:0010012)1.95929554
81Hand muscle atrophy (HP:0009130)1.95832283
82Truncus arteriosus (HP:0001660)1.94921690
83Obstructive sleep apnea (HP:0002870)1.94420575
84Rapidly progressive (HP:0003678)1.92865141
85Annular pancreas (HP:0001734)1.92589807
86Progressive cerebellar ataxia (HP:0002073)1.91116469
87Neoplasm of the heart (HP:0100544)1.90137468
88Postural instability (HP:0002172)1.89662440
89Exercise-induced myalgia (HP:0003738)1.89597881
90Precocious puberty (HP:0000826)1.88791635
91Long palpebral fissure (HP:0000637)1.88381312
92Dilatation of the ascending aorta (HP:0005111)1.88322237
93Aplasia/Hypoplasia of the brainstem (HP:0007362)1.87971926
94Hypoplasia of the brainstem (HP:0002365)1.87971926
95Apathy (HP:0000741)1.87580096
96Trigonocephaly (HP:0000243)1.87078217
97Stereotypic behavior (HP:0000733)1.85343893
98Buphthalmos (HP:0000557)1.84590808
99Peripheral hypomyelination (HP:0007182)1.84303959
100Distal lower limb amyotrophy (HP:0008944)1.83583695
101Abnormality of the phalanges of the hallux (HP:0010057)1.83013863
102Amblyopia (HP:0000646)1.81835898
103Septo-optic dysplasia (HP:0100842)1.81650593
104Genu recurvatum (HP:0002816)1.81364815
105Abnormality of oral frenula (HP:0000190)1.81305043
106Bronchomalacia (HP:0002780)1.81208276
107Mildly elevated creatine phosphokinase (HP:0008180)1.80692520
108Ankle contracture (HP:0006466)1.80522120
109Resting tremor (HP:0002322)1.80072743
110Epileptic encephalopathy (HP:0200134)1.79952564
111Scapular winging (HP:0003691)1.79659198
112Truncal ataxia (HP:0002078)1.79593513
113Generalized hypotonia (HP:0001290)1.79225640
114Abnormality of the distal phalanx of the thumb (HP:0009617)1.78909099
115Amyotrophic lateral sclerosis (HP:0007354)1.78738419
116Failure to thrive in infancy (HP:0001531)1.78609693
117Akinesia (HP:0002304)1.78600195
118Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.78145829
119Dysdiadochokinesis (HP:0002075)1.77802017
120Lymphangioma (HP:0100764)1.76909152
121Broad phalanges of the hand (HP:0009768)1.76603298
122Mitral valve prolapse (HP:0001634)1.76582972
123Deviation of the hallux (HP:0010051)1.76425781
124Hallux valgus (HP:0001822)1.75557864
125Aqueductal stenosis (HP:0002410)1.74931886
126Hyporeflexia of lower limbs (HP:0002600)1.73610727
127Hammertoe (HP:0001765)1.73606114
128Premature rupture of membranes (HP:0001788)1.73344183
129Striae distensae (HP:0001065)1.73039225
130Increased connective tissue (HP:0009025)1.72399907
131Sudden death (HP:0001699)1.71905179
132Thin ribs (HP:0000883)1.71853436
133Spastic gait (HP:0002064)1.71524654
134Drooling (HP:0002307)1.71318055
135Frequent falls (HP:0002359)1.71092069
136Lower limb muscle weakness (HP:0007340)1.70998328
137Spina bifida occulta (HP:0003298)1.70857501
138Neurofibrillary tangles (HP:0002185)1.69696438
139Diminished motivation (HP:0000745)1.69599309
140Disproportionate tall stature (HP:0001519)1.69087377
141Impaired smooth pursuit (HP:0007772)1.69046037
142Long toe (HP:0010511)1.69044191
143Abnormality of the pulmonary veins (HP:0011718)1.68639326
144Short 4th metacarpal (HP:0010044)1.68020366
145Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.68020366
146Laryngomalacia (HP:0001601)1.67325552
147Broad finger (HP:0001500)1.66656352
148Tracheomalacia (HP:0002779)1.65392766
149Broad thumb (HP:0011304)1.65270316
150Stridor (HP:0010307)1.64425511
151Asymmetric growth (HP:0100555)1.63928801
152Bowel incontinence (HP:0002607)1.63417507
153Intellectual disability, severe (HP:0010864)1.61502923
154Autism (HP:0000717)1.59314398
155Excessive salivation (HP:0003781)1.59271377
156Sporadic (HP:0003745)1.59196550
157Supernumerary nipples (HP:0002558)1.58301873
158Patellar dislocation (HP:0002999)1.58243551
159Arnold-Chiari malformation (HP:0002308)1.57785705
160Hepatoblastoma (HP:0002884)1.57464346
161Metaphyseal cupping (HP:0003021)1.55914538

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.53902387
2MAP3K93.32575346
3MARK13.29974565
4CASK2.85806456
5NTRK32.62746680
6PKN22.61599311
7PAK62.47084252
8CAMKK12.30686536
9EPHA42.25485228
10PRKD32.20580531
11KSR22.14989979
12RIPK12.14800923
13DAPK22.07708280
14EEF2K1.93489572
15SIK21.89042603
16PDGFRA1.85057690
17MINK11.84847576
18TYRO31.82388440
19TTN1.78048041
20NTRK21.72816741
21MAP3K41.72121190
22NTRK11.68581741
23DYRK21.67191435
24KSR11.64191508
25TAOK11.57363171
26PHKG11.51306590
27PHKG21.51306590
28ICK1.45711590
29RET1.45102378
30MAP3K101.44317450
31CAMK1G1.43673113
32LATS21.42011870
33ALK1.41633285
34DDR21.41331390
35TNK21.40089625
36SCYL21.29071200
37MAP3K21.26429614
38SGK2231.22670462
39SGK4941.22670462
40CDK51.22411385
41PRKCH1.20341852
42STK381.15964613
43MARK21.14572697
44UHMK11.11986384
45LMTK21.09579734
46SIK11.08223954
47DMPK1.05105749
48PTK61.04668404
49PAK31.04415632
50CAMKK21.04333768
51STK111.02192990
52CAMK1D1.01633099
53BMX0.97151654
54FGFR40.96674854
55MAPK120.93236258
56PINK10.93067871
57MAP2K40.92995952
58MAP3K70.90168980
59MAPK150.89783714
60SMG10.89443478
61DYRK1A0.87436001
62FGFR20.87039426
63TNIK0.86824108
64SGK20.83129204
65EPHB20.81544006
66RPS6KC10.80339324
67RPS6KL10.80339324
68ARAF0.79799706
69CDK150.77069197
70PDGFRB0.76906504
71CDC42BPA0.76138158
72NEK10.75957077
73BRAF0.75713408
74PTK20.73841750
75PKN10.73530652
76MAP3K60.72815666
77CDK180.72622138
78RPS6KA20.72110968
79FES0.71686851
80FER0.71173794
81DAPK10.70176162
82RPS6KA60.70049907
83CDK140.67297735
84CDK11A0.66338847
85CAMK10.64313901
86PRKD10.62091781
87FGFR10.59735539
88ROCK10.58435078
89MTOR0.57687725
90PRKD20.57084761
91DAPK30.56892104
92CAMK2B0.56818931
93PRKAA10.56106073
94PDPK10.55075778
95CAMK40.54478555
96FYN0.53906367
97MAP3K110.53198461
98PAK20.52812635
99EPHB10.52178423
100PDK10.51571102
101MAPK130.51304917
102MAP2K10.49499025
103ILK0.49475784
104DYRK1B0.49002274
105LIMK10.48713238
106PRKCG0.48693343
107PRKCZ0.48389239
108SGK30.47736098
109ROCK20.46801386
110CSNK1G20.46699553
111RPS6KA30.46688066
112SGK10.45201943
113ERBB20.44631315
114MAP2K70.44012423
115MAP3K10.43701821
116HIPK20.41769713
117PRPF4B0.41055131
118WNK10.40004456
119RAF10.39857021
120PIK3CA0.39438216
121MAPK100.38874354
122MAPK80.38329389
123SRC0.38311202
124CDK120.37186516
125RPS6KA10.37112568
126MAP3K130.37058836
127RIPK40.36809388

Predicted pathways (KEGG)

RankGene SetZ-score
1Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.07059432
2Circadian entrainment_Homo sapiens_hsa047131.97226662
3Synaptic vesicle cycle_Homo sapiens_hsa047211.93315482
4Olfactory transduction_Homo sapiens_hsa047401.92395189
5Long-term potentiation_Homo sapiens_hsa047201.87199150
6Glutamatergic synapse_Homo sapiens_hsa047241.74330489
7GABAergic synapse_Homo sapiens_hsa047271.69697709
8Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.68917944
9Aldosterone synthesis and secretion_Homo sapiens_hsa049251.64731407
10Nicotine addiction_Homo sapiens_hsa050331.61002646
11Dopaminergic synapse_Homo sapiens_hsa047281.60818608
12Cholinergic synapse_Homo sapiens_hsa047251.60762998
13Gastric acid secretion_Homo sapiens_hsa049711.60006290
14Glioma_Homo sapiens_hsa052141.59195984
15Salivary secretion_Homo sapiens_hsa049701.58150789
16Type II diabetes mellitus_Homo sapiens_hsa049301.57510801
17Morphine addiction_Homo sapiens_hsa050321.57314392
18Amphetamine addiction_Homo sapiens_hsa050311.52854505
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.50920028
20Oxytocin signaling pathway_Homo sapiens_hsa049211.50601847
21Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.49749272
22Insulin secretion_Homo sapiens_hsa049111.49349495
23Basal cell carcinoma_Homo sapiens_hsa052171.47565342
24GnRH signaling pathway_Homo sapiens_hsa049121.42503736
25Gap junction_Homo sapiens_hsa045401.40700631
26Estrogen signaling pathway_Homo sapiens_hsa049151.39306281
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.35540764
28Cocaine addiction_Homo sapiens_hsa050301.34895330
29Renin secretion_Homo sapiens_hsa049241.33495921
30Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.30967833
31Dilated cardiomyopathy_Homo sapiens_hsa054141.30526481
32mTOR signaling pathway_Homo sapiens_hsa041501.29491308
33Axon guidance_Homo sapiens_hsa043601.27743865
34Long-term depression_Homo sapiens_hsa047301.23356496
35Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.22500929
36Nitrogen metabolism_Homo sapiens_hsa009101.21590626
37ErbB signaling pathway_Homo sapiens_hsa040121.16755988
38Endometrial cancer_Homo sapiens_hsa052131.16168230
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.15078716
40VEGF signaling pathway_Homo sapiens_hsa043701.13044230
41Melanogenesis_Homo sapiens_hsa049161.08544921
42Hedgehog signaling pathway_Homo sapiens_hsa043401.07066115
43Phospholipase D signaling pathway_Homo sapiens_hsa040721.06841275
44Dorso-ventral axis formation_Homo sapiens_hsa043201.05993496
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.05864293
46Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.05534849
47Non-small cell lung cancer_Homo sapiens_hsa052231.05438888
48Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05358673
49cAMP signaling pathway_Homo sapiens_hsa040241.04747878
50Chronic myeloid leukemia_Homo sapiens_hsa052201.04458175
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03780080
52Calcium signaling pathway_Homo sapiens_hsa040201.02608359
53Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.02132382
54Thyroid hormone signaling pathway_Homo sapiens_hsa049191.01506142
55Renal cell carcinoma_Homo sapiens_hsa052110.94562312
56Insulin signaling pathway_Homo sapiens_hsa049100.94157534
57Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.92004266
58Longevity regulating pathway - mammal_Homo sapiens_hsa042110.91575671
59Focal adhesion_Homo sapiens_hsa045100.91546539
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.90876463
61Carbohydrate digestion and absorption_Homo sapiens_hsa049730.90541241
62Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89560748
63Proteoglycans in cancer_Homo sapiens_hsa052050.88369430
64Prion diseases_Homo sapiens_hsa050200.87287513
65Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.86693169
66Colorectal cancer_Homo sapiens_hsa052100.86116189
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84376392
68Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.82333310
69Cardiac muscle contraction_Homo sapiens_hsa042600.81710461
70MAPK signaling pathway_Homo sapiens_hsa040100.81442233
71Rap1 signaling pathway_Homo sapiens_hsa040150.81090442
72Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.80775810
73Taste transduction_Homo sapiens_hsa047420.80454190
74Endocytosis_Homo sapiens_hsa041440.79869581
75Choline metabolism in cancer_Homo sapiens_hsa052310.79317915
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.77824747
77Sulfur relay system_Homo sapiens_hsa041220.77300294
78Serotonergic synapse_Homo sapiens_hsa047260.75405942
79Ovarian steroidogenesis_Homo sapiens_hsa049130.74809808
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73994056
81Glucagon signaling pathway_Homo sapiens_hsa049220.73867178
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73600689
83Bladder cancer_Homo sapiens_hsa052190.73090241
84AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.72440778
85Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.71754891
86AMPK signaling pathway_Homo sapiens_hsa041520.70956022
87Platelet activation_Homo sapiens_hsa046110.70492493
88Inositol phosphate metabolism_Homo sapiens_hsa005620.69721158
89Lysine degradation_Homo sapiens_hsa003100.69204040
90Insulin resistance_Homo sapiens_hsa049310.68930309
91Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.68725162
92Thyroid hormone synthesis_Homo sapiens_hsa049180.68724274
93Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.68698320
94Glycerophospholipid metabolism_Homo sapiens_hsa005640.68259970
95Phototransduction_Homo sapiens_hsa047440.66304937
96Oocyte meiosis_Homo sapiens_hsa041140.64328928
97Prolactin signaling pathway_Homo sapiens_hsa049170.64242942
98Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63567740
99Amoebiasis_Homo sapiens_hsa051460.62897734
100Pancreatic secretion_Homo sapiens_hsa049720.62399967
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62271190
102Hippo signaling pathway_Homo sapiens_hsa043900.61877211
103Sphingolipid signaling pathway_Homo sapiens_hsa040710.61657361
104Pancreatic cancer_Homo sapiens_hsa052120.61137301
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.60372636
106Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59706416
107Acute myeloid leukemia_Homo sapiens_hsa052210.59598501
108Ras signaling pathway_Homo sapiens_hsa040140.58282308
109Bile secretion_Homo sapiens_hsa049760.57235947
110Tight junction_Homo sapiens_hsa045300.56945183
111Wnt signaling pathway_Homo sapiens_hsa043100.56814255
112Notch signaling pathway_Homo sapiens_hsa043300.56744586
113Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54521826
114Chemokine signaling pathway_Homo sapiens_hsa040620.53654054
115ECM-receptor interaction_Homo sapiens_hsa045120.51357699
116Adherens junction_Homo sapiens_hsa045200.49831840
117MicroRNAs in cancer_Homo sapiens_hsa052060.48658528
118Glycosaminoglycan degradation_Homo sapiens_hsa005310.44703026
119Pathways in cancer_Homo sapiens_hsa052000.44568729

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