ANKRD50

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)3.99165883
2paraxial mesoderm development (GO:0048339)3.79289412
3neuron projection extension involved in neuron projection guidance (GO:1902284)3.75233081
4axon extension involved in axon guidance (GO:0048846)3.75233081
5cell adhesion mediated by integrin (GO:0033627)3.57209260
6cytoskeletal anchoring at plasma membrane (GO:0007016)3.55139300
7layer formation in cerebral cortex (GO:0021819)3.42505192
8chondrocyte proliferation (GO:0035988)3.41474562
9protein heterotrimerization (GO:0070208)3.39388450
10artery development (GO:0060840)3.37711767
11hippo signaling (GO:0035329)3.35067053
12collagen fibril organization (GO:0030199)3.22343238
13negative regulation of catenin import into nucleus (GO:0035414)3.19908337
14negative regulation of fatty acid transport (GO:2000192)3.14808569
15retina vasculature morphogenesis in camera-type eye (GO:0061299)3.12708510
16establishment of nucleus localization (GO:0040023)3.12278984
17cell migration involved in sprouting angiogenesis (GO:0002042)3.10255799
18planar cell polarity pathway involved in neural tube closure (GO:0090179)3.07679252
19insulin-like growth factor receptor signaling pathway (GO:0048009)3.07027029
20stress fiber assembly (GO:0043149)3.02130696
21regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.00344305
22hemidesmosome assembly (GO:0031581)3.00318401
23sequestering of extracellular ligand from receptor (GO:0035581)2.98416985
24negative regulation of keratinocyte proliferation (GO:0010839)2.95205348
25endodermal cell differentiation (GO:0035987)2.93042902
26ganglion development (GO:0061548)2.90798837
27negative chemotaxis (GO:0050919)2.90339228
28adherens junction assembly (GO:0034333)2.83674327
29axon extension (GO:0048675)2.82006389
30regulation of NFAT protein import into nucleus (GO:0051532)2.77718273
31protein localization to endosome (GO:0036010)2.77491288
32Notch signaling involved in heart development (GO:0061314)2.77358237
33semaphorin-plexin signaling pathway (GO:0071526)2.76676686
34cell migration in hindbrain (GO:0021535)2.76632025
35regulation of axon extension involved in axon guidance (GO:0048841)2.76544588
36morphogenesis of an epithelial sheet (GO:0002011)2.75672872
37skin morphogenesis (GO:0043589)2.75022198
38cell-substrate junction assembly (GO:0007044)2.72071476
39polarized epithelial cell differentiation (GO:0030859)2.69713821
40cell surface receptor signaling pathway involved in heart development (GO:0061311)2.65857924
41presynaptic membrane assembly (GO:0097105)2.62159966
42neuron remodeling (GO:0016322)2.61339780
43neuron recognition (GO:0008038)2.61221289
44locomotory exploration behavior (GO:0035641)2.60752423
45positive regulation of axon extension (GO:0045773)2.59992940
46regulation of cardioblast differentiation (GO:0051890)2.59446961
47bone trabecula formation (GO:0060346)2.59412854
48vascular endothelial growth factor signaling pathway (GO:0038084)2.58679142
49nuclear pore complex assembly (GO:0051292)2.58203866
50cardiac myofibril assembly (GO:0055003)2.55928916
51regulation of axon guidance (GO:1902667)2.55013898
52protein targeting to plasma membrane (GO:0072661)2.54992781
53protein localization to cell surface (GO:0034394)2.54094128
54regulation of tight junction assembly (GO:2000810)2.52560900
55substrate-dependent cell migration (GO:0006929)2.52425439
56embryonic retina morphogenesis in camera-type eye (GO:0060059)2.51784202
57dendrite morphogenesis (GO:0048813)2.51547312
58regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.48555098
59dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.48512033
60gastrulation with mouth forming second (GO:0001702)2.48334180
61neuron projection extension (GO:1990138)2.48257376
62regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.47432265
63establishment of tissue polarity (GO:0007164)2.46502132
64establishment of planar polarity (GO:0001736)2.46502132
65limb bud formation (GO:0060174)2.45820178
66central nervous system projection neuron axonogenesis (GO:0021952)2.44953551
67neural crest cell development (GO:0014032)2.44551133
68lateral sprouting from an epithelium (GO:0060601)2.43615918
69adherens junction organization (GO:0034332)2.43424663
70epithelial cell-cell adhesion (GO:0090136)2.43240851
71apical protein localization (GO:0045176)2.42674462
72basement membrane organization (GO:0071711)2.41999336
73cytoplasmic mRNA processing body assembly (GO:0033962)2.40002994
74cell communication by electrical coupling (GO:0010644)2.39697860
75axonal fasciculation (GO:0007413)2.39207807
76negative regulation of axon extension involved in axon guidance (GO:0048843)2.37278216
77camera-type eye morphogenesis (GO:0048593)2.37174208
78synaptic vesicle maturation (GO:0016188)2.36763037
79endocardial cushion development (GO:0003197)2.36217654
80presynaptic membrane organization (GO:0097090)2.35822640
81ectodermal placode formation (GO:0060788)2.33982235
82blood vessel endothelial cell migration (GO:0043534)2.32738498
83cell-substrate adherens junction assembly (GO:0007045)2.32358747
84focal adhesion assembly (GO:0048041)2.32358747
85collagen metabolic process (GO:0032963)2.31487244
86nuclear pore organization (GO:0006999)2.31452458
87renal filtration (GO:0097205)2.31272786
88embryonic camera-type eye morphogenesis (GO:0048596)2.30456483
89G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.30349741
90mesenchymal-epithelial cell signaling (GO:0060638)2.29706907
91body morphogenesis (GO:0010171)2.29190657
92activation of protein kinase A activity (GO:0034199)2.27846972
93embryonic foregut morphogenesis (GO:0048617)2.27440257
94nucleus localization (GO:0051647)2.27326998
95notochord development (GO:0030903)2.26157716
96asymmetric protein localization (GO:0008105)2.25670912
97facial nerve structural organization (GO:0021612)2.25384614
98dendritic spine morphogenesis (GO:0060997)2.25218162
99multicellular organismal macromolecule metabolic process (GO:0044259)2.24808406
100collagen catabolic process (GO:0030574)2.24442448
101positive regulation of fibroblast migration (GO:0010763)2.24107306
102negative regulation of chondrocyte differentiation (GO:0032331)2.23733564
103myoblast fusion (GO:0007520)2.23707124
104lymphangiogenesis (GO:0001946)2.23616388
105pyrimidine nucleobase catabolic process (GO:0006208)2.23350408
106developmental cell growth (GO:0048588)2.22522020
107positive regulation of catenin import into nucleus (GO:0035413)2.22275593
108convergent extension (GO:0060026)2.21918034
109cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.21866943
110regulation of short-term neuronal synaptic plasticity (GO:0048172)2.21849031
111smooth muscle tissue development (GO:0048745)2.21211698
112regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.20792258
113regulation of catenin import into nucleus (GO:0035412)2.20067177
114kidney mesenchyme development (GO:0072074)2.19265955
115cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.18790695
116positive regulation of epithelial to mesenchymal transition (GO:0010718)2.18608543
117craniofacial suture morphogenesis (GO:0097094)2.18081405
118developmental growth involved in morphogenesis (GO:0060560)2.18043653
119SMAD protein complex assembly (GO:0007183)2.17616807
120positive regulation of glycogen biosynthetic process (GO:0045725)2.17460281
121wound healing, spreading of epidermal cells (GO:0035313)2.16638032
122positive regulation of endothelial cell apoptotic process (GO:2000353)2.16451987
123NLS-bearing protein import into nucleus (GO:0006607)2.16218711
124chondrocyte development (GO:0002063)2.15887561
125extracellular matrix disassembly (GO:0022617)2.15754750
126heart morphogenesis (GO:0003007)2.15599899
127central nervous system neuron axonogenesis (GO:0021955)2.15195511
128glial cell proliferation (GO:0014009)2.14871728
129Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.14639427
130regulation of establishment of planar polarity (GO:0090175)2.14219886
131mesodermal cell differentiation (GO:0048333)2.13942220
132dorsal/ventral axis specification (GO:0009950)2.13931928
133negative regulation of DNA repair (GO:0045738)2.13921106
134branching involved in salivary gland morphogenesis (GO:0060445)2.13892038
135lens morphogenesis in camera-type eye (GO:0002089)2.13648310
136metanephric mesenchyme development (GO:0072075)2.13617652
137regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.13089136
138synaptic vesicle docking involved in exocytosis (GO:0016081)2.13033694
139coronary vasculature morphogenesis (GO:0060977)2.12779821
140genitalia morphogenesis (GO:0035112)2.12643187
141mesenchymal cell development (GO:0014031)2.12434644
142anatomical structure arrangement (GO:0048532)2.12321811
143sodium ion export (GO:0071436)2.12094592
144regulation of epithelial cell differentiation involved in kidney development (GO:2000696)2.11452339
145anterior/posterior axis specification, embryo (GO:0008595)2.11216104
146regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.11190417
147negative regulation of axon guidance (GO:1902668)2.11142853
148negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.11133845
149establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.10701661
150syncytium formation (GO:0006949)2.10465658
151mitotic sister chromatid cohesion (GO:0007064)2.10290900
152apoptotic cell clearance (GO:0043277)2.10227200
153eye morphogenesis (GO:0048592)2.09580642
154regulation of transforming growth factor beta2 production (GO:0032909)2.09291433
155pre-miRNA processing (GO:0031054)2.08261763
156positive regulation of cardiac muscle cell differentiation (GO:2000727)2.08117363
157calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.07679220
158negative regulation of cartilage development (GO:0061037)2.05735690
159epithelial tube branching involved in lung morphogenesis (GO:0060441)2.05615033
160regulation of cardiac muscle cell differentiation (GO:2000725)2.05405252

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human3.67877547
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.61202420
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.69590862
4GBX2_23144817_ChIP-Seq_PC3_Human2.59582747
5EZH2_22144423_ChIP-Seq_EOC_Human2.44550413
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.33126115
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.30064780
8WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.29807112
9EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.14028330
10RARG_19884340_ChIP-ChIP_MEFs_Mouse2.13282278
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.11839050
12SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.09098294
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.06611080
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.06611080
15* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.05195072
16TAF15_26573619_Chip-Seq_HEK293_Human2.01039007
17FUS_26573619_Chip-Seq_HEK293_Human1.98334072
18TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.97839058
19ZFP281_18757296_ChIP-ChIP_E14_Mouse1.87286946
20PIAS1_25552417_ChIP-Seq_VCAP_Human1.85198886
21CLOCK_20551151_ChIP-Seq_293T_Human1.84812587
22EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.84356963
23* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.83301864
24EP300_21415370_ChIP-Seq_HL-1_Mouse1.83184664
25* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.80070675
26JARID2_20064375_ChIP-Seq_MESCs_Mouse1.73175753
27SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.72981916
28SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.70359867
29* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.70330849
30OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.70329125
31KDM2B_26808549_Chip-Seq_K562_Human1.70157259
32SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.69823719
33NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.69699964
34NRF2_20460467_ChIP-Seq_MEFs_Mouse1.69699964
35WT1_19549856_ChIP-ChIP_CCG9911_Human1.69661435
36SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.68665310
37EWS_26573619_Chip-Seq_HEK293_Human1.67609603
38DROSHA_22980978_ChIP-Seq_HELA_Human1.67380812
39KDM2B_26808549_Chip-Seq_SUP-B15_Human1.66961479
40DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.65600907
41TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.63502708
42JARID2_20075857_ChIP-Seq_MESCs_Mouse1.63270290
43IGF1R_20145208_ChIP-Seq_DFB_Human1.62367656
44KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.62116646
45EED_16625203_ChIP-ChIP_MESCs_Mouse1.62091340
46SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.61868731
47EZH2_27304074_Chip-Seq_ESCs_Mouse1.61554220
48* P300_19829295_ChIP-Seq_ESCs_Human1.61489115
49SMAD4_21799915_ChIP-Seq_A2780_Human1.60739994
50ZFP281_27345836_Chip-Seq_ESCs_Mouse1.60273281
51* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.59164017
52MTF2_20144788_ChIP-Seq_MESCs_Mouse1.58969819
53RNF2_27304074_Chip-Seq_ESCs_Mouse1.58934819
54SMAD_19615063_ChIP-ChIP_OVARY_Human1.58093324
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.54304144
56RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.53319798
57EGR1_19374776_ChIP-ChIP_THP-1_Human1.52445130
58YAP1_20516196_ChIP-Seq_MESCs_Mouse1.51958198
59* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.50578939
60ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.50450725
61TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.50236944
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.48893450
63TP53_16413492_ChIP-PET_HCT116_Human1.46266252
64ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.44451394
65* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.43371797
66KDM2B_26808549_Chip-Seq_DND41_Human1.43242898
67HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42263716
68SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.41783368
69TBX3_20139965_ChIP-Seq_MESCs_Mouse1.41027318
70TBX3_20139965_ChIP-Seq_ESCs_Mouse1.40961909
71STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.40321486
72SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.38754570
73ISL1_27105846_Chip-Seq_CPCs_Mouse1.38565605
74CJUN_26792858_Chip-Seq_BT549_Human1.37801454
75KDM2B_26808549_Chip-Seq_JURKAT_Human1.36941343
76SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.36913846
77ESR2_21235772_ChIP-Seq_MCF-7_Human1.36612975
78AHR_22903824_ChIP-Seq_MCF-7_Human1.36537005
79SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36042998
80WT1_25993318_ChIP-Seq_PODOCYTE_Human1.35095674
81CDX2_19796622_ChIP-Seq_MESCs_Mouse1.34331598
82TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.33375152
83EZH2_27294783_Chip-Seq_ESCs_Mouse1.32189596
84* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31118448
85SUZ12_27294783_Chip-Seq_ESCs_Mouse1.30472167
86SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.29739773
87RING1B_27294783_Chip-Seq_NPCs_Mouse1.29738490
88POU5F1_16153702_ChIP-ChIP_HESCs_Human1.29372251
89CTBP2_25329375_ChIP-Seq_LNCAP_Human1.29298031
90BRD4_25478319_ChIP-Seq_HGPS_Human1.28753610
91AR_21572438_ChIP-Seq_LNCaP_Human1.27975382
92STAT3_23295773_ChIP-Seq_U87_Human1.26939392
93NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.26683202
94TP53_20018659_ChIP-ChIP_R1E_Mouse1.26464265
95SALL4_18804426_ChIP-ChIP_XEN_Mouse1.25996545
96SOX9_24532713_ChIP-Seq_HFSC_Mouse1.25319267
97ZNF263_19887448_ChIP-Seq_K562_Human1.24389094
98* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24352211
99TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22365458
100CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.20813272
101TCF4_18268006_ChIP-ChIP_LS174T_Human1.20753871
102RING1B_27294783_Chip-Seq_ESCs_Mouse1.19842084
103RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.19602971
104PPAR_26484153_Chip-Seq_NCI-H1993_Human1.19515002
105ARNT_22903824_ChIP-Seq_MCF-7_Human1.18160619
106FOXO3_23340844_ChIP-Seq_DLD1_Human1.18098789
107ELK3_25401928_ChIP-Seq_HUVEC_Human1.17814668
108RBPJ_22232070_ChIP-Seq_NCS_Mouse1.16303855
109NANOG_18555785_Chip-Seq_ESCs_Mouse1.16225643
110PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.15974294
111CBX2_27304074_Chip-Seq_ESCs_Mouse1.15410931
112SOX9_26525672_Chip-Seq_HEART_Mouse1.15213836
113KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14695523
114* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.14380651
115* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.14161964
116CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.13188191
117ZNF274_21170338_ChIP-Seq_K562_Hela1.12892896
118TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.12353081
119ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.12182763
120HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.11660780
121TP53_18474530_ChIP-ChIP_U2OS_Human1.11423985
122RARB_27405468_Chip-Seq_BRAIN_Mouse1.09041914
123ESR1_21235772_ChIP-Seq_MCF-7_Human1.08785635
124KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.08346933
125FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.08144218
126ESR1_20079471_ChIP-ChIP_T-47D_Human1.07703433
127SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.06852540
128SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.06852540
129* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06839897
130* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06582622
131HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.06524650
132POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05635287
133TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05635287
134TBX20_22080862_ChIP-Seq_HEART_Mouse1.05606724
135TBX20_22328084_ChIP-Seq_HEART_Mouse1.05606724
136CTNNB1_20460455_ChIP-Seq_HCT116_Human1.04779820
137ERG_21242973_ChIP-ChIP_JURKAT_Human1.04005073
138SMAD3_21741376_ChIP-Seq_HESCs_Human1.03888546
139RUNX1_27514584_Chip-Seq_MCF-7_Human1.03544085
140UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.03536628
141NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03072763
142TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.02788828
143ER_23166858_ChIP-Seq_MCF-7_Human1.02455569
144AR_19668381_ChIP-Seq_PC3_Human1.01484179
145SALL1_21062744_ChIP-ChIP_HESCs_Human1.01150177
146* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.01023474
147RNF2_27304074_Chip-Seq_NSC_Mouse1.00201002
148* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00160928
149KLF5_25053715_ChIP-Seq_YYC3_Human0.99806384
150TCF4_23295773_ChIP-Seq_U87_Human0.99548180
151* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.99345856
152PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.98505671
153* GF1B_26923725_Chip-Seq_HPCs_Mouse0.98091768
154ATF3_27146783_Chip-Seq_COLON_Human0.97029242

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.31372417
2MP0003705_abnormal_hypodermis_morpholog3.78843187
3MP0005623_abnormal_meninges_morphology3.31224364
4MP0005275_abnormal_skin_tensile3.22157526
5MP0004272_abnormal_basement_membrane2.97630879
6MP0000537_abnormal_urethra_morphology2.35879267
7MP0005503_abnormal_tendon_morphology2.31049094
8MP0010352_gastrointestinal_tract_polyps2.11753279
9MP0001958_emphysema2.03909762
10MP0003279_aneurysm2.02309183
11MP0010234_abnormal_vibrissa_follicle1.94375199
12MP0003122_maternal_imprinting1.91523177
13MP0001299_abnormal_eye_distance/1.90392363
14MP0004858_abnormal_nervous_system1.87651503
15MP0003890_abnormal_embryonic-extraembry1.86545413
16MP0003566_abnormal_cell_adhesion1.86323939
17MP0003385_abnormal_body_wall1.85390656
18MP0000751_myopathy1.84251783
19MP0004859_abnormal_synaptic_plasticity1.76774503
20MP0003091_abnormal_cell_migration1.76023267
21MP0009053_abnormal_anal_canal1.72809501
22MP0010368_abnormal_lymphatic_system1.70073895
23MP0009780_abnormal_chondrocyte_physiolo1.69307748
24MP0005409_darkened_coat_color1.65696533
25MP0010030_abnormal_orbit_morphology1.65416281
26MP0000733_abnormal_muscle_development1.64474486
27MP0002697_abnormal_eye_size1.62903678
28MP0005076_abnormal_cell_differentiation1.61564869
29MP0000569_abnormal_digit_pigmentation1.60751644
30MP0000534_abnormal_ureter_morphology1.59411440
31MP0004084_abnormal_cardiac_muscle1.57889787
32MP0003045_fibrosis1.56200387
33MP0003283_abnormal_digestive_organ1.54457639
34MP0009384_cardiac_valve_regurgitation1.46884724
35MP0000013_abnormal_adipose_tissue1.43781415
36MP0003115_abnormal_respiratory_system1.43498626
37MP0005257_abnormal_intraocular_pressure1.41778441
38MP0006054_spinal_hemorrhage1.41727380
39MP0003942_abnormal_urinary_system1.40422378
40MP0002896_abnormal_bone_mineralization1.38362743
41MP0001293_anophthalmia1.35897030
42MP0001879_abnormal_lymphatic_vessel1.35787911
43MP0005187_abnormal_penis_morphology1.33002536
44MP0001849_ear_inflammation1.30681982
45MP0010678_abnormal_skin_adnexa1.30069598
46MP0000428_abnormal_craniofacial_morphol1.29598824
47MP0005508_abnormal_skeleton_morphology1.29534281
48MP0002877_abnormal_melanocyte_morpholog1.27694152
49MP0002092_abnormal_eye_morphology1.27676762
50MP0000383_abnormal_hair_follicle1.27171288
51MP0001286_abnormal_eye_development1.26573968
52MP0009250_abnormal_appendicular_skeleto1.22115629
53MP0004233_abnormal_muscle_weight1.19233377
54MP0003935_abnormal_craniofacial_develop1.19002391
55MP0003941_abnormal_skin_development1.18383251
56MP0003755_abnormal_palate_morphology1.15517445
57MP0002234_abnormal_pharynx_morphology1.14300362
58MP0002060_abnormal_skin_morphology1.10153213
59MP0003300_gastrointestinal_ulcer1.08251728
60MP0004087_abnormal_muscle_fiber1.08115784
61MP0005023_abnormal_wound_healing1.07255500
62MP0002108_abnormal_muscle_morphology1.06867755
63MP0005248_abnormal_Harderian_gland1.05739723
64MP0000049_abnormal_middle_ear1.05306475
65MP0005197_abnormal_uvea_morphology1.05077437
66MP0000750_abnormal_muscle_regeneration1.04357717
67MP0000767_abnormal_smooth_muscle1.03068755
68MP0002085_abnormal_embryonic_tissue1.03045554
69MP0000003_abnormal_adipose_tissue1.01039048
70MP0009703_decreased_birth_body1.00508418
71MP0001348_abnormal_lacrimal_gland1.00014746
72MP0003123_paternal_imprinting0.99999637
73MP0000579_abnormal_nail_morphology0.99638383
74MP0002925_abnormal_cardiovascular_devel0.98129727
75MP0006138_congestive_heart_failure0.98048066
76MP0001915_intracranial_hemorrhage0.97592649
77MP0003984_embryonic_growth_retardation0.96819050
78MP0000516_abnormal_urinary_system0.96768562
79MP0005367_renal/urinary_system_phenotyp0.96768562
80MP0002088_abnormal_embryonic_growth/wei0.95347053
81MP0003119_abnormal_digestive_system0.92583349
82MP0008961_abnormal_basal_metabolism0.92298360
83MP0002751_abnormal_autonomic_nervous0.92033923
84MP0000778_abnormal_nervous_system0.91071040
85MP0002932_abnormal_joint_morphology0.91049479
86MP0002086_abnormal_extraembryonic_tissu0.91003907
87MP0001672_abnormal_embryogenesis/_devel0.90955422
88MP0005380_embryogenesis_phenotype0.90955422
89MP0010630_abnormal_cardiac_muscle0.90753494
90MP0002009_preneoplasia0.90120000
91MP0002116_abnormal_craniofacial_bone0.89607417
92MP0003567_abnormal_fetal_cardiomyocyte0.89186157
93MP0002282_abnormal_trachea_morphology0.88868559
94MP0002177_abnormal_outer_ear0.87568262
95MP0000432_abnormal_head_morphology0.87374859
96MP0002089_abnormal_postnatal_growth/wei0.86329948
97MP0003121_genomic_imprinting0.85290373
98MP0002295_abnormal_pulmonary_circulatio0.84454909
99MP0008057_abnormal_DNA_replication0.84143209
100MP0005171_absent_coat_pigmentation0.84005547
101MP0002111_abnormal_tail_morphology0.83996608
102MP0002233_abnormal_nose_morphology0.83386474
103MP0000647_abnormal_sebaceous_gland0.83114603
104MP0004270_analgesia0.82666721
105MP0001188_hyperpigmentation0.82090569
106MP0003937_abnormal_limbs/digits/tail_de0.80929746
107MP0003635_abnormal_synaptic_transmissio0.80741767
108MP0002184_abnormal_innervation0.80718785
109MP0002168_other_aberrant_phenotype0.79566766
110MP0000759_abnormal_skeletal_muscle0.79424490
111MP0001340_abnormal_eyelid_morphology0.79097387
112MP0004811_abnormal_neuron_physiology0.78341790
113MP0004197_abnormal_fetal_growth/weight/0.78106687
114MP0002796_impaired_skin_barrier0.77652634
115MP0002114_abnormal_axial_skeleton0.77297515
116MP0002972_abnormal_cardiac_muscle0.77167188
117MP0001614_abnormal_blood_vessel0.77005391
118MP0002128_abnormal_blood_circulation0.76811856
119MP0002109_abnormal_limb_morphology0.76471226
120MP0002837_dystrophic_cardiac_calcinosis0.74898096
121MP0000762_abnormal_tongue_morphology0.74619848
122MP0001177_atelectasis0.73298123
123MP0003861_abnormal_nervous_system0.72228499
124MP0002084_abnormal_developmental_patter0.71840963
125MP0004185_abnormal_adipocyte_glucose0.71708288
126MP0008775_abnormal_heart_ventricle0.71107704
127MP0000163_abnormal_cartilage_morphology0.70660968
128MP0000462_abnormal_digestive_system0.70612849
129MP0003303_peritoneal_inflammation0.70449315
130MP0001544_abnormal_cardiovascular_syste0.70407738
131MP0005385_cardiovascular_system_phenoty0.70407738
132MP0000266_abnormal_heart_morphology0.70019067
133MP0002081_perinatal_lethality0.69903278

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.81020949
2Premature rupture of membranes (HP:0001788)4.61446209
3Shallow orbits (HP:0000586)4.18720648
4Cerebral aneurysm (HP:0004944)3.72838194
5Atrophic scars (HP:0001075)3.72416163
6Ankle contracture (HP:0006466)3.36547767
7Papillary thyroid carcinoma (HP:0002895)3.34344658
8Bladder diverticulum (HP:0000015)3.21273038
9Aortic dissection (HP:0002647)3.17563461
10Broad metatarsal (HP:0001783)3.15158353
11Fragile skin (HP:0001030)2.94677068
12Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.91917602
13Short 4th metacarpal (HP:0010044)2.91917602
14Dilatation of the ascending aorta (HP:0005111)2.91257622
15Mitral valve prolapse (HP:0001634)2.91186200
16Genu recurvatum (HP:0002816)2.82293133
17Aortic aneurysm (HP:0004942)2.82080852
18Bowel diverticulosis (HP:0005222)2.72983046
19Morphological abnormality of the middle ear (HP:0008609)2.62335695
20Increased connective tissue (HP:0009025)2.56542241
21Soft skin (HP:0000977)2.52135712
22Vertebral arch anomaly (HP:0008438)2.44993276
23Peritonitis (HP:0002586)2.42073177
24Cutaneous finger syndactyly (HP:0010554)2.36940778
25Abnormality of the 4th metacarpal (HP:0010012)2.34631787
26Overgrowth (HP:0001548)2.32325419
27Wrist flexion contracture (HP:0001239)2.32093099
28Absent frontal sinuses (HP:0002688)2.31824081
29Buphthalmos (HP:0000557)2.31660987
30Hyperacusis (HP:0010780)2.29481559
31Deviation of the hallux (HP:0010051)2.29279758
32Renal duplication (HP:0000075)2.27390569
33Type 1 muscle fiber predominance (HP:0003803)2.27052530
34Cutaneous syndactyly (HP:0012725)2.25626889
35Mildly elevated creatine phosphokinase (HP:0008180)2.25621719
36Increased variability in muscle fiber diameter (HP:0003557)2.22519405
37Hallux valgus (HP:0001822)2.20817967
38Subacute progressive viral hepatitis (HP:0006572)2.20723901
39Hypoventilation (HP:0002791)2.20031703
40Spinal rigidity (HP:0003306)2.19667007
41Thyroid carcinoma (HP:0002890)2.17387164
42Aneurysm (HP:0002617)2.17045668
43Bronchomalacia (HP:0002780)2.13902968
44Vascular tortuosity (HP:0004948)2.10694528
45Enlarged penis (HP:0000040)2.08781390
46Increased density of long bones (HP:0006392)2.07652714
47Termporal pattern (HP:0011008)2.06900169
48Insidious onset (HP:0003587)2.06900169
49Striae distensae (HP:0001065)2.06159938
50Hyperextensible skin (HP:0000974)2.05108188
51Wormian bones (HP:0002645)2.04438825
52Follicular hyperkeratosis (HP:0007502)2.04239105
53Abnormality of dentin (HP:0010299)2.02790472
54Macroorchidism (HP:0000053)2.02145169
55Lower limb amyotrophy (HP:0007210)2.00062726
56Lymphangioma (HP:0100764)1.99431629
57Asymmetry of the thorax (HP:0001555)1.98878775
58Deep philtrum (HP:0002002)1.96998790
59Abnormality of the ischium (HP:0003174)1.96569677
60Arterial tortuosity (HP:0005116)1.95716455
61Scapular winging (HP:0003691)1.95642848
62Mitral regurgitation (HP:0001653)1.91612533
63Pulmonic stenosis (HP:0001642)1.88600736
64Renovascular hypertension (HP:0100817)1.87866962
65Cortical dysplasia (HP:0002539)1.86582750
66Large earlobe (HP:0009748)1.85709571
67Difficulty climbing stairs (HP:0003551)1.85691477
68Joint laxity (HP:0001388)1.85660421
69Wide anterior fontanel (HP:0000260)1.85303363
70Abnormality of skeletal muscle fiber size (HP:0012084)1.84825835
71Cervical subluxation (HP:0003308)1.84728942
72Blue sclerae (HP:0000592)1.84325163
73Neonatal short-limb short stature (HP:0008921)1.83254360
74Coronal craniosynostosis (HP:0004440)1.83152660
75Flat cornea (HP:0007720)1.82297713
76Ankyloglossia (HP:0010296)1.82247368
77Curly hair (HP:0002212)1.82167049
78Hepatoblastoma (HP:0002884)1.81999256
79Camptodactyly of toe (HP:0001836)1.81928758
80Thin bony cortex (HP:0002753)1.81735962
81Right ventricular cardiomyopathy (HP:0011663)1.81356766
82Limited hip movement (HP:0008800)1.80563958
83Pointed chin (HP:0000307)1.79405374
84Broad ribs (HP:0000885)1.79293885
85Midline defect of the nose (HP:0004122)1.78778167
86Distal upper limb amyotrophy (HP:0007149)1.78479544
87Upper limb amyotrophy (HP:0009129)1.78479544
88Abnormality of oral frenula (HP:0000190)1.77731742
89Distal lower limb amyotrophy (HP:0008944)1.77210402
90Milia (HP:0001056)1.77116010
91Skull defect (HP:0001362)1.76820241
92Difficulty running (HP:0009046)1.75682692
93Absent eyebrow (HP:0002223)1.75468104
94Achilles tendon contracture (HP:0001771)1.74016680
95Venous abnormality (HP:0002624)1.73986328
96Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.72550740
97Elfin facies (HP:0004428)1.72448536
98Transitional cell carcinoma of the bladder (HP:0006740)1.71306737
99Neoplasm of the heart (HP:0100544)1.71219356
100Turricephaly (HP:0000262)1.70494271
101Hyporeflexia of lower limbs (HP:0002600)1.70198794
102Drooling (HP:0002307)1.69757026
103Long toe (HP:0010511)1.68775731
104Hypercortisolism (HP:0001578)1.66332128
105Aqueductal stenosis (HP:0002410)1.65488336
106Sudden death (HP:0001699)1.63650832
107Bladder neoplasm (HP:0009725)1.63423459
108Bladder carcinoma (HP:0002862)1.63423459
109Narrow palate (HP:0000189)1.63319784
110Abnormality of the distal phalanx of the thumb (HP:0009617)1.62571832
111Arnold-Chiari malformation (HP:0002308)1.62441100
112Heterotopia (HP:0002282)1.62376304
113Congenital glaucoma (HP:0001087)1.60678541
114Overriding aorta (HP:0002623)1.59931531
115Venous insufficiency (HP:0005293)1.58865705
116Long nose (HP:0003189)1.58537309
117Fibroma (HP:0010614)1.57574542
118Rectal prolapse (HP:0002035)1.56977144
119Disproportionate tall stature (HP:0001519)1.56014249
120Aplasia involving bones of the extremities (HP:0009825)1.55769220
121Aplasia involving bones of the upper limbs (HP:0009823)1.55769220
122Aplasia of the phalanges of the hand (HP:0009802)1.55769220
123Leiomyosarcoma (HP:0100243)1.55731085
124Uterine leiomyosarcoma (HP:0002891)1.55731085
125Broad long bones (HP:0005622)1.55302908
126Slender build (HP:0001533)1.55077108
127Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.55020126
128Fibrous tissue neoplasm (HP:0012316)1.54148404
129Cubitus valgus (HP:0002967)1.53611740
130Limb-girdle muscle weakness (HP:0003325)1.53139138
131Hypoplasia of the iris (HP:0007676)1.51792974
132Absent eyelashes (HP:0000561)1.51766429
133Breech presentation (HP:0001623)1.51166462
134Exotropia (HP:0000577)1.51142022
135Vitreoretinal degeneration (HP:0000655)1.51057185
136Bifid tongue (HP:0010297)1.50745120
137Medulloblastoma (HP:0002885)1.49530355
138Myelomeningocele (HP:0002475)1.48736402
139Knee flexion contracture (HP:0006380)1.48672034
140Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.47617099
141Short chin (HP:0000331)1.47458522
142Short nail (HP:0001799)1.46829033
143Abnormality of the lower motor neuron (HP:0002366)1.46715507
144Omphalocele (HP:0001539)1.46068914
145Syringomyelia (HP:0003396)1.45278934
146Spinal cord lesions (HP:0100561)1.45278934
147Pulmonary artery stenosis (HP:0004415)1.44360257
148Triangular face (HP:0000325)1.44071521
149Hammertoe (HP:0001765)1.43269823
150Cystic hygroma (HP:0000476)1.43195094
151Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.42489883
152Excessive salivation (HP:0003781)1.41821341
153Aplasia/Hypoplasia of metatarsal bones (HP:0001964)1.41743703
154Malignant gastrointestinal tract tumors (HP:0006749)1.41677582
155Gastrointestinal carcinoma (HP:0002672)1.41677582
156Astrocytoma (HP:0009592)1.41189919
157Abnormality of the astrocytes (HP:0100707)1.41189919
158Hypoplasia of the maxilla (HP:0000327)1.39995126
159Glioma (HP:0009733)1.39992542

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.50668490
2CASK3.30395932
3TTN3.13473846
4PDGFRA3.12994040
5LATS22.95288314
6DDR22.86409190
7PKN22.84643831
8LATS12.59831541
9RIPK12.49748915
10TNIK2.35119068
11EPHB22.35109419
12BCR2.30493562
13TIE12.18222809
14AKT32.11345180
15MKNK22.06481571
16FER2.03051825
17BRD42.02571322
18PNCK1.92180035
19BMPR1B1.88169291
20MAP3K91.86166857
21DMPK1.79381321
22TAF11.76041375
23PTK61.75739830
24MARK11.62797008
25PAK31.60240097
26NTRK11.55058429
27PTK21.53078725
28PAK61.52813126
29PDGFRB1.50482198
30PRKD31.50254024
31TYRO31.50041045
32MKNK11.47744549
33RET1.47074388
34EEF2K1.46169035
35FGFR21.44698795
36FGFR11.38826436
37STK38L1.37163430
38BMX1.36976350
39MAP3K41.32104919
40PAK21.29168300
41SCYL21.28011424
42TRIM281.26722962
43SIK11.22770410
44MAP3K101.18989226
45KSR21.18972603
46MAP3K21.18817804
47MINK11.18640170
48KSR11.15961943
49YES11.13897832
50MAP2K71.11220019
51LMTK21.09401988
52ALK1.08174213
53CAMK1G1.07750219
54LRRK21.06618983
55MTOR1.06478675
56ERBB41.05362589
57CAMKK11.04957799
58FLT31.04535965
59PRKCH1.01958135
60ROCK11.01824591
61EPHA21.00917986
62ICK1.00095125
63ERBB30.99666130
64NTRK30.99358775
65NTRK20.99092645
66BRSK20.97109947
67LIMK10.94573139
68SGK20.91297110
69SIK20.91014792
70PAK40.90641103
71STK390.90520329
72CDK120.89281966
73CAMK1D0.87533555
74NEK10.85656255
75STK380.82497828
76TAOK10.82223401
77MAP3K60.80486095
78CDC42BPA0.80145532
79ROCK20.80083609
80FRK0.78357083
81SGK30.76507702
82PTK2B0.75702835
83PRKD10.75198055
84CSNK1G10.75114371
85MAP2K10.74590250
86FGFR30.72217336
87ILK0.72006678
88SRPK10.71766675
89PHKG20.71630835
90PHKG10.71630835
91MARK20.71131198
92TGFBR10.69909816
93MAP3K70.69363950
94ERBB20.67580512
95PLK20.66622466
96WNK30.65647944
97CDK60.64771134
98TGFBR20.63115120
99NEK90.63039715
100MYLK0.62976430
101MET0.61952559
102SGK4940.61755400
103SGK2230.61755400
104EPHA30.61334817
105STK110.59143772
106WNK10.58610612
107STK30.56872671
108CDK50.55968116
109CDK140.55767793
110INSR0.54536388
111RPS6KA40.53555482
112PRKCE0.53191096
113RPS6KA20.52583532
114SRC0.51910922
115DYRK1B0.50077641
116CDK150.49258201
117FYN0.47857316
118MOS0.47736352
119MST1R0.47463313
120CDK180.47131562
121STK240.44675345
122CSNK1A1L0.44384723
123ERN10.42843466
124CSNK1G20.42692352
125TESK10.42495586
126UHMK10.42340824
127PIK3CA0.42172087
128DYRK30.41983470
129INSRR0.41971807
130NEK20.41332372
131DAPK20.41085770
132TTK0.41063572
133TSSK60.38811569
134MAPK80.37179804
135CDK11A0.37062075
136CSNK1G30.36815640
137MAP2K40.36048006
138RPS6KB10.35756031
139ADRBK10.35460465
140CDK90.35414114
141ATM0.35272409
142MAPK90.35045314
143CSNK1D0.34667056
144MAPK100.33605785
145WEE10.32420388

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.21662236
2Focal adhesion_Homo sapiens_hsa045101.95224339
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.95061783
4Dilated cardiomyopathy_Homo sapiens_hsa054141.89292358
5Adherens junction_Homo sapiens_hsa045201.74321072
6Proteoglycans in cancer_Homo sapiens_hsa052051.65265641
7Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.62070942
8Axon guidance_Homo sapiens_hsa043601.61637171
9Hippo signaling pathway_Homo sapiens_hsa043901.56992856
10Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.55175439
11Glioma_Homo sapiens_hsa052141.54784578
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.42553043
13Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.41741218
14Basal cell carcinoma_Homo sapiens_hsa052171.41537648
15Endometrial cancer_Homo sapiens_hsa052131.41058596
16Chronic myeloid leukemia_Homo sapiens_hsa052201.40033025
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.38735909
18Amoebiasis_Homo sapiens_hsa051461.38075841
19AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.36437910
20Estrogen signaling pathway_Homo sapiens_hsa049151.34264640
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.34189192
22Gap junction_Homo sapiens_hsa045401.32333684
23Small cell lung cancer_Homo sapiens_hsa052221.30831293
24Hedgehog signaling pathway_Homo sapiens_hsa043401.28880229
25Melanogenesis_Homo sapiens_hsa049161.26427199
26MicroRNAs in cancer_Homo sapiens_hsa052061.25801283
27Dorso-ventral axis formation_Homo sapiens_hsa043201.25768161
28Renal cell carcinoma_Homo sapiens_hsa052111.25249866
29GnRH signaling pathway_Homo sapiens_hsa049121.23639620
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.22457785
31Bladder cancer_Homo sapiens_hsa052191.22379563
32Viral myocarditis_Homo sapiens_hsa054161.20665922
33Tight junction_Homo sapiens_hsa045301.19976107
34Colorectal cancer_Homo sapiens_hsa052101.19255022
35mTOR signaling pathway_Homo sapiens_hsa041501.19125317
36TGF-beta signaling pathway_Homo sapiens_hsa043501.15609485
37Rap1 signaling pathway_Homo sapiens_hsa040151.15576996
38Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.14513896
39ErbB signaling pathway_Homo sapiens_hsa040121.13934325
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.13514151
41Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.11614474
42Protein digestion and absorption_Homo sapiens_hsa049741.11260689
43Long-term potentiation_Homo sapiens_hsa047201.10767003
44Neurotrophin signaling pathway_Homo sapiens_hsa047221.10241353
45Regulation of actin cytoskeleton_Homo sapiens_hsa048101.09946131
46Wnt signaling pathway_Homo sapiens_hsa043101.09742771
47Gastric acid secretion_Homo sapiens_hsa049711.08631821
48Oxytocin signaling pathway_Homo sapiens_hsa049211.08356367
49Thyroid hormone signaling pathway_Homo sapiens_hsa049191.06860074
50Renin secretion_Homo sapiens_hsa049241.05685210
51Cholinergic synapse_Homo sapiens_hsa047251.04756278
52Melanoma_Homo sapiens_hsa052181.03978727
53VEGF signaling pathway_Homo sapiens_hsa043701.03827771
54Type II diabetes mellitus_Homo sapiens_hsa049301.03392439
55Circadian entrainment_Homo sapiens_hsa047131.03387031
56Dopaminergic synapse_Homo sapiens_hsa047281.00573411
57Central carbon metabolism in cancer_Homo sapiens_hsa052300.99868749
58Long-term depression_Homo sapiens_hsa047300.97906172
59Pancreatic cancer_Homo sapiens_hsa052120.97214472
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.96835019
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.96819452
62Lysine degradation_Homo sapiens_hsa003100.94418912
63Salivary secretion_Homo sapiens_hsa049700.93489403
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.92900543
65Platelet activation_Homo sapiens_hsa046110.90867797
66Cocaine addiction_Homo sapiens_hsa050300.90564896
67Non-small cell lung cancer_Homo sapiens_hsa052230.89994350
68Synaptic vesicle cycle_Homo sapiens_hsa047210.89968650
69Leukocyte transendothelial migration_Homo sapiens_hsa046700.89841192
70Nicotine addiction_Homo sapiens_hsa050330.89521866
71Pathways in cancer_Homo sapiens_hsa052000.89205694
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.88875957
73PI3K-Akt signaling pathway_Homo sapiens_hsa041510.86668491
74Insulin secretion_Homo sapiens_hsa049110.85933563
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.85106946
76Prostate cancer_Homo sapiens_hsa052150.84711633
77Insulin signaling pathway_Homo sapiens_hsa049100.83716137
78MAPK signaling pathway_Homo sapiens_hsa040100.83002875
79Endocytosis_Homo sapiens_hsa041440.82359693
80GABAergic synapse_Homo sapiens_hsa047270.81264826
81Thyroid cancer_Homo sapiens_hsa052160.81003939
82mRNA surveillance pathway_Homo sapiens_hsa030150.78351579
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.78075452
84Amphetamine addiction_Homo sapiens_hsa050310.77517076
85Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.77197715
86cAMP signaling pathway_Homo sapiens_hsa040240.76914281
87Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.76763026
88Longevity regulating pathway - mammal_Homo sapiens_hsa042110.76417854
89Ras signaling pathway_Homo sapiens_hsa040140.75700742
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75046161
91Prolactin signaling pathway_Homo sapiens_hsa049170.74987562
92Olfactory transduction_Homo sapiens_hsa047400.74275903
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73696373
94p53 signaling pathway_Homo sapiens_hsa041150.73255341
95Inositol phosphate metabolism_Homo sapiens_hsa005620.73143158
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72965097
97FoxO signaling pathway_Homo sapiens_hsa040680.72844374
98Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.72548912
99Toxoplasmosis_Homo sapiens_hsa051450.71927320
100Cell cycle_Homo sapiens_hsa041100.71133217
101Glutamatergic synapse_Homo sapiens_hsa047240.71101044
102HIF-1 signaling pathway_Homo sapiens_hsa040660.69818837
103Non-homologous end-joining_Homo sapiens_hsa034500.69565870
104Alcoholism_Homo sapiens_hsa050340.68971697
105Thyroid hormone synthesis_Homo sapiens_hsa049180.67849828
106Morphine addiction_Homo sapiens_hsa050320.67155961
107AMPK signaling pathway_Homo sapiens_hsa041520.66421036
108Notch signaling pathway_Homo sapiens_hsa043300.65360332
109Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65200304
110Insulin resistance_Homo sapiens_hsa049310.64681419
111Oocyte meiosis_Homo sapiens_hsa041140.64654988
112Choline metabolism in cancer_Homo sapiens_hsa052310.64358057
113Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63355376
114Circadian rhythm_Homo sapiens_hsa047100.60735947
115Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.59092869
116Taste transduction_Homo sapiens_hsa047420.50935079
117Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48641377
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.47965685
119Serotonergic synapse_Homo sapiens_hsa047260.46441823

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