ANKRD13A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.31874796
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.31874796
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.12222917
4negative regulation of cell killing (GO:0031342)5.12222917
5modulation by symbiont of host immune response (GO:0052553)4.95726929
6positive regulation by symbiont of host defense response (GO:0052509)4.95726929
7modulation by symbiont of host defense response (GO:0052031)4.95726929
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.95726929
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.95726929
10positive regulation by organism of defense response of other organism involved in symbiotic interact4.95726929
11antigen processing and presentation of endogenous antigen (GO:0019883)4.68996681
12ribosomal small subunit assembly (GO:0000028)4.63949050
13antigen processing and presentation via MHC class Ib (GO:0002475)4.20430457
14macrophage activation involved in immune response (GO:0002281)4.15791037
15positive regulation of B cell differentiation (GO:0045579)4.12323840
16detection of molecule of bacterial origin (GO:0032490)4.06882965
17definitive hemopoiesis (GO:0060216)4.06435696
18detection of other organism (GO:0098543)4.03485279
19positive regulation of gamma-delta T cell activation (GO:0046645)3.97694650
20DNA unwinding involved in DNA replication (GO:0006268)3.97213832
21viral transcription (GO:0019083)3.96932192
22regulation of interferon-beta biosynthetic process (GO:0045357)3.94863293
23Arp2/3 complex-mediated actin nucleation (GO:0034314)3.85760827
24neutrophil activation involved in immune response (GO:0002283)3.83275012
25cellular extravasation (GO:0045123)3.81370185
26translational termination (GO:0006415)3.78728413
27negative regulation of erythrocyte differentiation (GO:0045647)3.76983763
28detection of external biotic stimulus (GO:0098581)3.76861382
29detection of bacterium (GO:0016045)3.74619815
30antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.67061572
31positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.66029712
32response to peptidoglycan (GO:0032494)3.61104412
33response to interleukin-15 (GO:0070672)3.52922978
34megakaryocyte development (GO:0035855)3.49496827
35response to host immune response (GO:0052572)3.44868666
36response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.44868666
37response to host (GO:0075136)3.44537759
38response to host defenses (GO:0052200)3.44537759
39response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.44537759
40negative regulation of lymphocyte mediated immunity (GO:0002707)3.41172438
41positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.38476236
42negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.36481958
43translational elongation (GO:0006414)3.34464118
44negative regulation of phagocytosis (GO:0050765)3.32461945
45negative regulation of interleukin-12 production (GO:0032695)3.32181384
46regulation of B cell differentiation (GO:0045577)3.31759818
47DNA strand elongation involved in DNA replication (GO:0006271)3.29816481
48negative thymic T cell selection (GO:0045060)3.24127330
49regulation of gamma-delta T cell differentiation (GO:0045586)3.23334814
50positive thymic T cell selection (GO:0045059)3.20297612
51nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.20269648
52detection of biotic stimulus (GO:0009595)3.19452457
53negative regulation of T cell mediated immunity (GO:0002710)3.19101756
54SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.17172580
55germinal center formation (GO:0002467)3.17126294
56negative regulation of T-helper cell differentiation (GO:0045623)3.16555945
57negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.16555945
58microglial cell activation (GO:0001774)3.16328920
59negative T cell selection (GO:0043383)3.16021195
603-UTR-mediated mRNA stabilization (GO:0070935)3.15966257
61positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.15415703
62DNA strand elongation (GO:0022616)3.13773059
63T cell homeostasis (GO:0043029)3.12892290
64production of molecular mediator involved in inflammatory response (GO:0002532)3.10045911
65protein targeting to ER (GO:0045047)3.09145985
66cellular response to interleukin-15 (GO:0071350)3.08530906
67cotranslational protein targeting to membrane (GO:0006613)3.08322921
68regulation of mast cell degranulation (GO:0043304)3.06400780
69telomere maintenance via semi-conservative replication (GO:0032201)3.05247040
70negative regulation of leukocyte mediated immunity (GO:0002704)3.00428633
71viral life cycle (GO:0019058)2.98589296
72protein localization to kinetochore (GO:0034501)2.97876136
73protein localization to chromosome, centromeric region (GO:0071459)2.97198628
74positive T cell selection (GO:0043368)2.96855553
75ribosomal small subunit biogenesis (GO:0042274)2.96524897
76establishment of protein localization to endoplasmic reticulum (GO:0072599)2.96327823
77translesion synthesis (GO:0019985)2.95941252
78neutrophil activation (GO:0042119)2.95832808
79response to muramyl dipeptide (GO:0032495)2.94163070
80regulation of erythrocyte differentiation (GO:0045646)2.93847488
81macrophage activation (GO:0042116)2.92954463
82response to type I interferon (GO:0034340)2.92667815
83myeloid cell activation involved in immune response (GO:0002275)2.92402699
84cellular response to type I interferon (GO:0071357)2.91145813
85type I interferon signaling pathway (GO:0060337)2.91145813
86neutrophil mediated immunity (GO:0002446)2.90655988
87positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.88805684
88regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.88375830
89immunoglobulin mediated immune response (GO:0016064)2.88359077
90translational initiation (GO:0006413)2.88198296
91regulation of gamma-delta T cell activation (GO:0046643)2.87890224
92regulation of T-helper 2 cell differentiation (GO:0045628)2.87707085
93protein localization to endoplasmic reticulum (GO:0070972)2.87204621
94regulation of mast cell activation involved in immune response (GO:0033006)2.86572449
95regulation of histone H3-K9 methylation (GO:0051570)2.86530073
96cellular protein complex disassembly (GO:0043624)2.85116485
97DNA replication initiation (GO:0006270)2.83607299
98negative regulation of type 2 immune response (GO:0002829)2.82981839
99regulation of necroptotic process (GO:0060544)2.80045128
100regulation of dendritic cell antigen processing and presentation (GO:0002604)2.79365676
101hypotonic response (GO:0006971)2.78624321
102regulation of leukocyte degranulation (GO:0043300)2.78375038
103telomere maintenance via recombination (GO:0000722)2.76319780
104T cell selection (GO:0045058)2.76098314
105actin nucleation (GO:0045010)2.76069383
106protein complex disassembly (GO:0043241)2.76048356
107regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.75714197
108maturation of SSU-rRNA (GO:0030490)2.73976126
109positive regulation of mast cell activation (GO:0033005)2.72838900
110positive regulation of granulocyte differentiation (GO:0030854)2.72545422
111B cell receptor signaling pathway (GO:0050853)2.70312132
112regulation of mast cell activation (GO:0033003)2.69928052
113respiratory burst (GO:0045730)2.69908886
114hepatocyte apoptotic process (GO:0097284)2.69749471
115defense response to protozoan (GO:0042832)2.69726277
116regulation of tolerance induction (GO:0002643)2.69585893
117regulation of interleukin-12 biosynthetic process (GO:0045075)2.69214850
118dosage compensation (GO:0007549)2.68575453
119regulation of myeloid leukocyte mediated immunity (GO:0002886)2.68370175
120regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.67895965
121granulocyte activation (GO:0036230)2.67685549
122interferon-gamma-mediated signaling pathway (GO:0060333)2.66819802
123regulation of B cell receptor signaling pathway (GO:0050855)2.65162815
124regulation of platelet aggregation (GO:0090330)2.64231381
125regulation of macrophage cytokine production (GO:0010935)2.62701397
126regulation of T cell tolerance induction (GO:0002664)2.62367236
127mitotic recombination (GO:0006312)2.61718152
128angiogenesis involved in wound healing (GO:0060055)2.61365255
129regulation of alpha-beta T cell proliferation (GO:0046640)2.60862992
130negative regulation of interleukin-6 production (GO:0032715)2.59792994
131positive regulation of interferon-alpha production (GO:0032727)2.58888850
132T cell migration (GO:0072678)2.58806803
133mast cell activation (GO:0045576)2.58795547
134leukocyte migration involved in inflammatory response (GO:0002523)2.57807758
135regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.56915767
136cellular hyperosmotic response (GO:0071474)2.56303680
137mitotic sister chromatid cohesion (GO:0007064)2.56221774
138positive regulation of protein deacetylation (GO:0090312)2.55960002
139negative regulation of RNA splicing (GO:0033119)2.55772225
140embryonic hemopoiesis (GO:0035162)2.55564693
141tolerance induction (GO:0002507)2.54756601
142mature B cell differentiation involved in immune response (GO:0002313)2.54548427
143thymic T cell selection (GO:0045061)2.54353111
144dendritic cell migration (GO:0036336)2.52866638
145positive regulation of lamellipodium assembly (GO:0010592)2.51757410
146negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.51308687
147lipopolysaccharide-mediated signaling pathway (GO:0031663)2.50811315
148DNA deamination (GO:0045006)2.50665350
149nuclear-transcribed mRNA catabolic process (GO:0000956)2.50462911
150positive regulation of histone deacetylation (GO:0031065)2.50374835
151pinocytosis (GO:0006907)2.50235300
152macromolecular complex disassembly (GO:0032984)2.49658351
153natural killer cell differentiation (GO:0001779)2.48574494
154B cell mediated immunity (GO:0019724)2.48524981
155lymphocyte homeostasis (GO:0002260)2.47584524
156response to protozoan (GO:0001562)2.45210365
157negative regulation of necroptotic process (GO:0060546)2.45053376
158pentose-phosphate shunt (GO:0006098)2.45044023
159ncRNA 3-end processing (GO:0043628)2.43339038
160mature B cell differentiation (GO:0002335)2.42966844
161protein-DNA complex disassembly (GO:0032986)2.42907554
162nucleosome disassembly (GO:0006337)2.42907554
163RNA stabilization (GO:0043489)2.42732725
164mRNA stabilization (GO:0048255)2.42732725
165leukocyte homeostasis (GO:0001776)2.42076257
166leukocyte aggregation (GO:0070486)2.41974513
167mRNA catabolic process (GO:0006402)2.39635529
168mitotic chromosome condensation (GO:0007076)2.38585985
169RNA catabolic process (GO:0006401)2.36963029
170Peyers patch development (GO:0048541)2.34323259
171mucosal-associated lymphoid tissue development (GO:0048537)2.34323259
172NIK/NF-kappaB signaling (GO:0038061)2.34309716
173lymph node development (GO:0048535)2.33862042
174myeloid dendritic cell activation (GO:0001773)2.32833906
175nuclear pore complex assembly (GO:0051292)2.32716004
176alternative mRNA splicing, via spliceosome (GO:0000380)2.32678495
177IMP metabolic process (GO:0046040)2.31717033
178negative regulation of histone methylation (GO:0031061)2.30427368
179DNA duplex unwinding (GO:0032508)2.30037097
180germ cell migration (GO:0008354)2.29455588
181negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.29387329
182T cell apoptotic process (GO:0070231)2.29108057

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.86120590
2SCL_19346495_ChIP-Seq_HPC-7_Human3.24052927
3MYC_22102868_ChIP-Seq_BL_Human3.15255746
4SMAD_19615063_ChIP-ChIP_OVARY_Human3.13052995
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.06902921
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.01007751
7IRF8_22096565_ChIP-ChIP_GC-B_Human2.86569218
8VDR_21846776_ChIP-Seq_THP-1_Human2.85518446
9* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.83250180
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.81554716
11* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.53653806
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.38166639
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.30123161
14* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.29586047
15VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.25640506
16* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.24031750
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.22884757
18STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.22587840
19Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.21133767
20* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.17231400
21MYC_18555785_ChIP-Seq_MESCs_Mouse2.13588468
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.05263461
23VDR_24763502_ChIP-Seq_THP-1_Human2.03413593
24ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.02928887
25* TCF7_22412390_ChIP-Seq_EML_Mouse2.02593470
26MYB_26560356_Chip-Seq_TH2_Human2.01291195
27MAF_26560356_Chip-Seq_TH1_Human2.00483112
28* SPI1_23547873_ChIP-Seq_NB4_Human2.00192010
29IRF8_21731497_ChIP-ChIP_J774_Mouse1.96920541
30FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.91348355
31VDR_24787735_ChIP-Seq_THP-1_Human1.90120913
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.88845264
33UTX_26944678_Chip-Seq_JUKART_Human1.88819098
34BRD4_27068464_Chip-Seq_AML-cells_Mouse1.87761202
35NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.86648424
36MYB_26560356_Chip-Seq_TH1_Human1.85483653
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.81337571
38ELF1_17652178_ChIP-ChIP_JURKAT_Human1.78441358
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.78356698
40MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76260491
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.74927059
42STAT4_19710469_ChIP-ChIP_TH1__Mouse1.70713429
43SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.70649080
44BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.70128417
45SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.69369298
46GATA2_21666600_ChIP-Seq_HMVEC_Human1.66455669
47NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.63619042
48* IRF8_27001747_Chip-Seq_BMDM_Mouse1.62760568
49GATA1_22383799_ChIP-Seq_G1ME_Mouse1.60392013
50BP1_19119308_ChIP-ChIP_Hs578T_Human1.59653157
51FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.57842292
52* CIITA_25753668_ChIP-Seq_RAJI_Human1.57140483
53TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.55820058
54ERG_20887958_ChIP-Seq_HPC-7_Mouse1.53612361
55KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.50884345
56E2F1_21310950_ChIP-Seq_MCF-7_Human1.46692309
57MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.46189162
58MYC_19079543_ChIP-ChIP_MESCs_Mouse1.44771299
59* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.43191729
60TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43104648
61GATA2_22383799_ChIP-Seq_G1ME_Mouse1.41975696
62E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.41000388
63STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.40380507
64* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.39847666
65KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.37296499
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.35813103
67NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.35127189
68MYC_18358816_ChIP-ChIP_MESCs_Mouse1.33903099
69MAF_26560356_Chip-Seq_TH2_Human1.32849491
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.32549901
71RUNX_20019798_ChIP-Seq_JUKART_Human1.32264298
72IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.32086004
73* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.32043801
74VDR_23849224_ChIP-Seq_CD4+_Human1.31771718
75XRN2_22483619_ChIP-Seq_HELA_Human1.31504267
76GATA1_19941826_ChIP-Seq_K562_Human1.30891836
77KDM2B_26808549_Chip-Seq_DND41_Human1.30793053
78* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.29935732
79NOTCH1_21737748_ChIP-Seq_TLL_Human1.28233885
80CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.28199272
81* SPI1_23127762_ChIP-Seq_K562_Human1.27522230
82RARG_19884340_ChIP-ChIP_MEFs_Mouse1.24049228
83* FOXP3_21729870_ChIP-Seq_TREG_Human1.23093772
84AR_21909140_ChIP-Seq_LNCAP_Human1.21417137
85KDM2B_26808549_Chip-Seq_JURKAT_Human1.20659753
86GATA1_22025678_ChIP-Seq_K562_Human1.19108697
87STAT6_21828071_ChIP-Seq_BEAS2B_Human1.18113302
88GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.17436468
89STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.16290703
90GATA3_26560356_Chip-Seq_TH2_Human1.15039208
91SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12707188
92GATA2_19941826_ChIP-Seq_K562_Human1.11934234
93BRD4_25478319_ChIP-Seq_HGPS_Human1.11314932
94RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.10173932
95NCOR1_26117541_ChIP-Seq_K562_Human1.09024484
96NELFA_20434984_ChIP-Seq_ESCs_Mouse1.08102888
97* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.07320315
98SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.05541398
99SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.05541398
100PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05500033
101EST1_17652178_ChIP-ChIP_JURKAT_Human1.05455121
102GATA1_19941827_ChIP-Seq_MEL_Mouse1.05272594
103FOXO3_23340844_ChIP-Seq_DLD1_Human1.04938149
104* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.04304804
105GATA3_27048872_Chip-Seq_THYMUS_Human1.03780391
106PU_27001747_Chip-Seq_BMDM_Mouse1.02881837
107TFEB_21752829_ChIP-Seq_HELA_Human1.02861577
108KDM5A_27292631_Chip-Seq_BREAST_Human1.01578586
109TP63_17297297_ChIP-ChIP_HaCaT_Human0.99931617
110* SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.99594075
111ZFX_18555785_ChIP-Seq_MESCs_Mouse0.99388791
112PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99330895
113ETS1_20019798_ChIP-Seq_JURKAT_Human0.98870777
114THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.98765778
115PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98449382
116* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98355290
117GABP_19822575_ChIP-Seq_HepG2_Human0.96909214
118CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.96469158
119FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.96194088
120* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95700431
121RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.95660171
122KLF4_18555785_ChIP-Seq_MESCs_Mouse0.95082608
123DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.94547972
124GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94365697
125NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.94026136
126MYCN_18555785_ChIP-Seq_MESCs_Mouse0.93861018
127PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92855407
128KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92687873
129FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.90666659
130DCP1A_22483619_ChIP-Seq_HELA_Human0.88748181
131* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87889466
132ETS1_22383799_ChIP-Seq_G1ME_Mouse0.87640510
133CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86308407
134CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85889574
135KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.85049075
136ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.83900384
137TP53_16413492_ChIP-PET_HCT116_Human0.83897257
138STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.82277766
139GATA1_19941827_ChIP-Seq_MEL86_Mouse0.82150464
140VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.81555974
141SOX9_24532713_ChIP-Seq_HFSC_Mouse0.80610626
142CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80380884

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system3.57335643
2MP0001835_abnormal_antigen_presentation2.97838905
3MP0004808_abnormal_hematopoietic_stem2.76578039
4MP0005397_hematopoietic_system_phenotyp2.65371104
5MP0001545_abnormal_hematopoietic_system2.65371104
6MP0000685_abnormal_immune_system2.60521031
7MP0009278_abnormal_bone_marrow2.57539482
8MP0008438_abnormal_cutaneous_collagen2.53587398
9MP0003705_abnormal_hypodermis_morpholog2.32248191
10MP0003300_gastrointestinal_ulcer2.31083323
11MP0001958_emphysema2.29642028
12MP0005464_abnormal_platelet_physiology2.27617739
13MP0002398_abnormal_bone_marrow2.25685080
14MP0003303_peritoneal_inflammation2.21800216
15MP0000465_gastrointestinal_hemorrhage2.21433117
16MP0001800_abnormal_humoral_immune2.16549737
17MP0003763_abnormal_thymus_physiology2.07775034
18MP0003436_decreased_susceptibility_to2.06365626
19MP0002452_abnormal_antigen_presenting2.05638250
20MP0009785_altered_susceptibility_to2.05440855
21MP0000490_abnormal_crypts_of2.03042658
22MP0002420_abnormal_adaptive_immunity2.02597861
23MP0005671_abnormal_response_to2.01829950
24MP0005025_abnormal_response_to2.01605385
25MP0001819_abnormal_immune_cell2.00040560
26MP0005174_abnormal_tail_pigmentation1.98317049
27MP0010094_abnormal_chromosome_stability1.96363496
28MP0003693_abnormal_embryo_hatching1.95572866
29MP0002166_altered_tumor_susceptibility1.94224016
30MP0002723_abnormal_immune_serum1.91179766
31MP0010352_gastrointestinal_tract_polyps1.89784047
32MP0003279_aneurysm1.89185963
33MP0008057_abnormal_DNA_replication1.89055539
34MP0005000_abnormal_immune_tolerance1.89019524
35MP0000689_abnormal_spleen_morphology1.87036663
36MP0000716_abnormal_immune_system1.86992873
37MP0003091_abnormal_cell_migration1.85797459
38MP0002722_abnormal_immune_system1.84142587
39MP0006054_spinal_hemorrhage1.83122903
40MP0002419_abnormal_innate_immunity1.82207300
41MP0001790_abnormal_immune_system1.81961977
42MP0005387_immune_system_phenotype1.81961977
43MP0010155_abnormal_intestine_physiology1.78912581
44MP0009333_abnormal_splenocyte_physiolog1.78084626
45MP0001873_stomach_inflammation1.75808297
46MP0002429_abnormal_blood_cell1.74262319
47MP0003077_abnormal_cell_cycle1.71337719
48MP0008260_abnormal_autophagy1.69199791
49MP0002405_respiratory_system_inflammati1.68919658
50MP0003111_abnormal_nucleus_morphology1.68158146
51MP0003866_abnormal_defecation1.67028617
52MP0005451_abnormal_body_composition1.65187439
53MP0000569_abnormal_digit_pigmentation1.62752216
54MP0004957_abnormal_blastocyst_morpholog1.60926254
55MP0005275_abnormal_skin_tensile1.60826072
56MP0002148_abnormal_hypersensitivity_rea1.59788320
57MP0000703_abnormal_thymus_morphology1.57494753
58MP0008007_abnormal_cellular_replicative1.52043860
59MP0003183_abnormal_peptide_metabolism1.46865848
60MP0004883_abnormal_blood_vessel1.46419850
61MP0010307_abnormal_tumor_latency1.45376620
62MP0002006_tumorigenesis1.43894563
63MP0001853_heart_inflammation1.42530915
64MP0004947_skin_inflammation1.42198859
65MP0002019_abnormal_tumor_incidence1.35962363
66MP0002877_abnormal_melanocyte_morpholog1.35886636
67MP0002998_abnormal_bone_remodeling1.35447660
68MP0005164_abnormal_response_to1.33072275
69MP0001845_abnormal_inflammatory_respons1.27149140
70MP0003724_increased_susceptibility_to1.24298389
71MP0003950_abnormal_plasma_membrane1.19497153
72MP0005075_abnormal_melanosome_morpholog1.16631248
73MP0004147_increased_porphyrin_level1.14759931
74MP0000858_altered_metastatic_potential1.11890502
75MP0003045_fibrosis1.11469105
76MP0003656_abnormal_erythrocyte_physiolo1.10429464
77MP0008058_abnormal_DNA_repair1.09780857
78MP0000313_abnormal_cell_death1.07135823
79MP0002095_abnormal_skin_pigmentation1.06509071
80MP0003191_abnormal_cellular_cholesterol1.05800566
81MP0000350_abnormal_cell_proliferation1.05064724
82MP0001542_abnormal_bone_strength1.03872631
83MP0000767_abnormal_smooth_muscle1.03775076
84MP0005058_abnormal_lysosome_morphology1.03595698
85MP0005410_abnormal_fertilization1.02592687
86MP0003566_abnormal_cell_adhesion1.01808493
87MP0005503_abnormal_tendon_morphology1.01600674
88MP0003448_altered_tumor_morphology0.99975219
89MP0001730_embryonic_growth_arrest0.99264167
90MP0005390_skeleton_phenotype0.98771944
91MP0001348_abnormal_lacrimal_gland0.98141138
92MP0006082_CNS_inflammation0.97133032
93MP0009764_decreased_sensitivity_to0.95327458
94MP0001533_abnormal_skeleton_physiology0.94220835
95MP0008469_abnormal_protein_level0.91516952
96MP0005076_abnormal_cell_differentiation0.91239047
97MP0004381_abnormal_hair_follicle0.91169982
98MP0002009_preneoplasia0.90580555
99MP0008004_abnormal_stomach_pH0.87383748
100MP0008877_abnormal_DNA_methylation0.86842894
101MP0005310_abnormal_salivary_gland0.86212496
102MP0003795_abnormal_bone_structure0.85582924
103MP0005023_abnormal_wound_healing0.85320218
104MP0005409_darkened_coat_color0.85279281
105MP0000249_abnormal_blood_vessel0.85221605
106MP0000477_abnormal_intestine_morphology0.85172628
107MP0003221_abnormal_cardiomyocyte_apopto0.85029726
108MP0003943_abnormal_hepatobiliary_system0.84704331
109MP0000343_altered_response_to0.84131575
110MP0003828_pulmonary_edema0.83883748
111MP0003172_abnormal_lysosome_physiology0.82622596
112MP0001851_eye_inflammation0.82522133
113MP0002933_joint_inflammation0.81350242
114MP0009384_cardiac_valve_regurgitation0.79919456
115MP0002060_abnormal_skin_morphology0.77590090
116MP0002086_abnormal_extraembryonic_tissu0.76287326
117MP0002080_prenatal_lethality0.75656159
118MP0000015_abnormal_ear_pigmentation0.74942297
119MP0009763_increased_sensitivity_to0.73322671
120MP0002133_abnormal_respiratory_system0.72896217
121MP0005388_respiratory_system_phenotype0.72896217
122MP0001663_abnormal_digestive_system0.72149516
123MP0001929_abnormal_gametogenesis0.71697879
124MP0005166_decreased_susceptibility_to0.68663362
125MP0001915_intracranial_hemorrhage0.68129304
126MP0005621_abnormal_cell_physiology0.67075755
127MP0002132_abnormal_respiratory_system0.67016613
128MP0003984_embryonic_growth_retardation0.65947711
129MP0000604_amyloidosis0.65883546
130MP0003786_premature_aging0.65831385
131MP0001697_abnormal_embryo_size0.65528460
132MP0004510_myositis0.65089822
133MP0009840_abnormal_foam_cell0.64420808
134MP0009931_abnormal_skin_appearance0.64081726
135MP0002088_abnormal_embryonic_growth/wei0.63174212
136MP0001879_abnormal_lymphatic_vessel0.61949138
137MP0003567_abnormal_fetal_cardiomyocyte0.61383293

Predicted human phenotypes

RankGene SetZ-score
1Thrombocytosis (HP:0001894)4.77463877
2Chronic otitis media (HP:0000389)4.41402042
3Peritonitis (HP:0002586)3.95448322
4IgM deficiency (HP:0002850)3.81736306
5Nasal polyposis (HP:0100582)3.81339020
6Recurrent viral infections (HP:0004429)3.78717413
7Cellulitis (HP:0100658)3.71777419
8Abnormality of the nasal mucosa (HP:0000433)3.70742966
9Recurrent abscess formation (HP:0002722)3.69465134
10Abnormality of cells of the erythroid lineage (HP:0012130)3.69390104
11Petechiae (HP:0000967)3.65947541
12Abnormal number of erythroid precursors (HP:0012131)3.63021904
13Elevated erythrocyte sedimentation rate (HP:0003565)3.56154574
14Recurrent bronchitis (HP:0002837)3.51173167
15Abnormal delayed hypersensitivity skin test (HP:0002963)3.49902011
16Gastrointestinal infarctions (HP:0005244)3.47327094
17Recurrent bacterial skin infections (HP:0005406)3.40763507
18Prolonged bleeding time (HP:0003010)3.39266847
19Myositis (HP:0100614)3.37759484
20Optic neuritis (HP:0100653)3.33986126
21Retrobulbar optic neuritis (HP:0100654)3.33986126
22Recurrent fungal infections (HP:0002841)3.33767689
23Eczematoid dermatitis (HP:0000976)3.24940426
24Panhypogammaglobulinemia (HP:0003139)3.22060533
25Gastrointestinal inflammation (HP:0004386)3.15700270
26Impaired platelet aggregation (HP:0003540)3.10781146
27Abnormal platelet function (HP:0011869)3.10781146
28Inflammation of the large intestine (HP:0002037)3.10346412
29Interstitial pulmonary disease (HP:0006530)3.04387954
30Abnormality of T cell physiology (HP:0011840)3.02938388
31Protrusio acetabuli (HP:0003179)2.99237487
32Recurrent gram-negative bacterial infections (HP:0005420)2.97604654
33Aortic aneurysm (HP:0004942)2.97105754
34Reticulocytopenia (HP:0001896)2.92866353
35Gingivitis (HP:0000230)2.91685030
36Acute myeloid leukemia (HP:0004808)2.88435752
37Colitis (HP:0002583)2.88034825
38Aplastic anemia (HP:0001915)2.87453343
39Spontaneous hematomas (HP:0007420)2.79615574
40Meningitis (HP:0001287)2.73156032
41Stomatitis (HP:0010280)2.70020395
42Abnormality of the peritoneum (HP:0002585)2.62828042
43Abnormality of T cells (HP:0002843)2.61807378
44Dilatation of the ascending aorta (HP:0005111)2.60952910
45Premature rupture of membranes (HP:0001788)2.60847210
46Epistaxis (HP:0000421)2.60454616
47Fatigue (HP:0012378)2.59569573
48B lymphocytopenia (HP:0010976)2.59169111
49Abnormality of B cell number (HP:0010975)2.59169111
50Spondylolisthesis (HP:0003302)2.58722020
51Abnormality of the fingertips (HP:0001211)2.57961799
52Agammaglobulinemia (HP:0004432)2.57196641
53Recurrent skin infections (HP:0001581)2.55659386
54Aortic dissection (HP:0002647)2.52528089
55Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.51702980
56Vascular tortuosity (HP:0004948)2.51171028
57Urticaria (HP:0001025)2.51159830
58Keratoconjunctivitis sicca (HP:0001097)2.47949090
59Increased IgE level (HP:0003212)2.47670522
60Pulmonary infiltrates (HP:0002113)2.46617742
61Hyperacusis (HP:0010780)2.41822805
62Recurrent cutaneous fungal infections (HP:0011370)2.39585641
63Chronic mucocutaneous candidiasis (HP:0002728)2.39585641
64Keratoconjunctivitis (HP:0001096)2.37453473
65Bronchitis (HP:0012387)2.37060142
66Abnormality of macrophages (HP:0004311)2.36130843
67Chest pain (HP:0100749)2.35729341
68Myelodysplasia (HP:0002863)2.35666412
69Abnormal platelet volume (HP:0011876)2.34889092
70Amaurosis fugax (HP:0100576)2.33009921
71Acute lymphatic leukemia (HP:0006721)2.30056676
72Arterial tortuosity (HP:0005116)2.29314612
73Chronic obstructive pulmonary disease (HP:0006510)2.28838397
74Obstructive lung disease (HP:0006536)2.28838397
75Hemoptysis (HP:0002105)2.28476405
76Pallor (HP:0000980)2.21684974
77Abnormality of cells of the lymphoid lineage (HP:0012140)2.21371412
78Osteomyelitis (HP:0002754)2.19032563
79Lymphopenia (HP:0001888)2.18757220
80Hematochezia (HP:0002573)2.16566305
81Papilloma (HP:0012740)2.14546870
82Verrucae (HP:0200043)2.14546870
83Autoimmune thrombocytopenia (HP:0001973)2.12008216
84Episodic fever (HP:0001954)2.11078628
85Arterial thrombosis (HP:0004420)2.09867707
86Basal cell carcinoma (HP:0002671)2.09635603
87Thyroiditis (HP:0100646)2.07383947
88Pustule (HP:0200039)2.05648181
89Poikiloderma (HP:0001029)2.04358147
90Vasculitis (HP:0002633)2.03918131
91Cutaneous melanoma (HP:0012056)2.03748129
92Lymphoma (HP:0002665)2.02595019
93Increased density of long bones (HP:0006392)2.01444353
94Gingival bleeding (HP:0000225)2.01159336
95Mediastinal lymphadenopathy (HP:0100721)2.01045540
96Leukocytosis (HP:0001974)2.00268198
9711 pairs of ribs (HP:0000878)2.00140089
98Osteolytic defects of the hand bones (HP:0009699)1.97686868
99Osteolytic defects of the phalanges of the hand (HP:0009771)1.97686868
100Periodontitis (HP:0000704)1.96599230
101Orchitis (HP:0100796)1.96540668
102Hypergammaglobulinemia (HP:0010702)1.96538743
103Aneurysm (HP:0002617)1.93983833
104Recurrent lower respiratory tract infections (HP:0002783)1.92773943
105High pitched voice (HP:0001620)1.92435738
106Abnormality of the thoracic spine (HP:0100711)1.91325889
107T lymphocytopenia (HP:0005403)1.90474265
108Pulmonary embolism (HP:0002204)1.89799860
109Chronic sinusitis (HP:0011109)1.88869677
110Subacute progressive viral hepatitis (HP:0006572)1.88837434
111Albinism (HP:0001022)1.88365396
112Thoracic kyphosis (HP:0002942)1.87753812
113Gastrointestinal stroma tumor (HP:0100723)1.86936510
114Polycythemia (HP:0001901)1.84874884
115Increased mean platelet volume (HP:0011877)1.84844788
116Anorexia (HP:0002039)1.83494511
117Granulocytopenia (HP:0001913)1.82820685
118Prominent nose (HP:0000448)1.81885719
119Sepsis (HP:0100806)1.81845139
120Skin ulcer (HP:0200042)1.81302585
121IgA deficiency (HP:0002720)1.80276368
122Glomerulopathy (HP:0100820)1.79371129
123Encephalitis (HP:0002383)1.77891007
124Thoracolumbar scoliosis (HP:0002944)1.77457377
125Recurrent pneumonia (HP:0006532)1.76060690
126Abnormality of T cell number (HP:0011839)1.75886210
127Syringomyelia (HP:0003396)1.75743121
128Spinal cord lesions (HP:0100561)1.75743121
129Slow saccadic eye movements (HP:0000514)1.75713359
130Bruising susceptibility (HP:0000978)1.75398917
131Chronic diarrhea (HP:0002028)1.74360056
132Hypochromic microcytic anemia (HP:0004840)1.73709840
133Genu recurvatum (HP:0002816)1.73476016
134Viral hepatitis (HP:0006562)1.73184889
135Eosinophilia (HP:0001880)1.72829719
136Entropion (HP:0000621)1.71430891
137Hypochromic anemia (HP:0001931)1.70965936
138Restrictive lung disease (HP:0002091)1.69801872
139Wormian bones (HP:0002645)1.69578289
140Emphysema (HP:0002097)1.69495926
141IgG deficiency (HP:0004315)1.69052841
142Abnormality of the heme biosynthetic pathway (HP:0010472)1.68916064
143Abnormality of the pericardium (HP:0001697)1.68009925
144Ankle contracture (HP:0006466)1.67850226

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.28979997
2RIPK43.63478460
3MAP4K13.52663485
4PKN22.65844390
5KIT2.52603368
6TRIB32.49957304
7BTK2.34138213
8FLT32.27662813
9MAP3K102.22853113
10PRPF4B2.16594322
11NEK21.95651871
12STK101.90471239
13JAK31.87354571
14CSF1R1.83493750
15WEE11.83019778
16MAP3K131.82624119
17PIK3CG1.81561241
18LRRK21.77223423
19ZAP701.74964326
20NME21.69547734
21CDC71.68275593
22RPS6KB21.66131305
23TEC1.64403851
24BLK1.63359208
25MAP3K31.56352883
26MAP2K31.54647367
27EPHB11.52563309
28GRK61.51078271
29TGFBR11.48920970
30PRKD21.45292155
31TBK11.43467326
32CDK121.41002515
33ERN11.36534894
34RPS6KA41.35417807
35SCYL21.34466461
36TAOK31.32227259
37CDK41.32141704
38TYK21.31077174
39KSR21.28760750
40AKT31.27407637
41IRAK41.26109969
42SYK1.25691011
43MAP3K21.25296049
44PIM11.22348854
45MAPKAPK31.20270649
46PAK41.19342987
47CLK11.19237641
48DYRK31.17217035
49TGFBR21.15709384
50FES1.13640637
51MATK1.12757418
52BMPR21.12280562
53PIM21.10660977
54MAP3K71.09714799
55MAP3K11.08417895
56MARK21.07820710
57PTK61.06575078
58STK41.04514450
59FGR1.03004294
60STK381.02061251
61TESK20.99789371
62ITK0.98510868
63IRAK10.98137708
64CDC42BPA0.95309622
65LCK0.91634408
66HCK0.91548516
67CDK70.90939024
68PTK2B0.90890993
69PASK0.90759712
70TRPM70.90019330
71TESK10.89968990
72MAP3K80.89716544
73CDK60.88277162
74ATR0.87236837
75IKBKB0.86893790
76BRSK20.85997720
77IKBKE0.85974341
78YES10.79929094
79SGK30.79482519
80WNK10.78730548
81MAPKAPK50.78478407
82KDR0.77638630
83PDGFRA0.77101655
84PDPK10.76631450
85CSK0.75206947
86SIK30.74666706
87SMG10.74394589
88MKNK10.73734470
89ACVR1B0.73183159
90MARK30.72918826
91BUB10.72248990
92MAP3K110.72048067
93LYN0.70458247
94MOS0.70330083
95MYLK0.69958339
96TXK0.68888976
97MAPK70.68445403
98PDGFRB0.68154652
99HIPK20.66249944
100SIK10.63529698
101ICK0.62610700
102ALK0.60702656
103GRK70.60425460
104CDK90.59818028
105RIPK10.59753802
106RET0.58824439
107MELK0.58396684
108SIK20.58329633
109EPHA30.57370445
110AURKB0.57325753
111SGK20.57047473
112TAOK20.56039307
113IRAK20.55936280
114CDK190.55462634
115MAPK110.54539284
116JAK20.53882291
117CAMKK20.53377957
118RAF10.53306597
119MAP3K60.52929329
120MAPKAPK20.52069385
121ILK0.51799950
122NLK0.50395659
123MAP3K50.50325221
124MAP3K140.50233336
125MAPK120.49889600
126FGFR30.49373300
127PRKCQ0.49064223
128TTN0.48285266
129FYN0.48160893
130MAPK40.47234429
131PAK20.47169715
132KSR10.46909707
133DYRK1B0.46712924
134TIE10.46057510
135PRKG20.45524876
136RPS6KA60.43901717
137TNK20.42342748
138STK30.41712521
139CHEK10.41140600
140NEK90.39194954
141TAOK10.38315082
142PDK10.37940449
143JAK10.37625612
144BRD40.37567986
145VRK10.37321761
146CHUK0.37194772
147FGFR40.34002799

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.60327413
2Ribosome_Homo sapiens_hsa030102.41401061
3Mismatch repair_Homo sapiens_hsa034302.34005927
4Primary immunodeficiency_Homo sapiens_hsa053402.30365444
5Base excision repair_Homo sapiens_hsa034102.17935322
6B cell receptor signaling pathway_Homo sapiens_hsa046622.15391683
7Leishmaniasis_Homo sapiens_hsa051402.08897746
8Antigen processing and presentation_Homo sapiens_hsa046122.05578922
9Staphylococcus aureus infection_Homo sapiens_hsa051501.90705538
10Graft-versus-host disease_Homo sapiens_hsa053321.76516778
11Autoimmune thyroid disease_Homo sapiens_hsa053201.71830995
12Spliceosome_Homo sapiens_hsa030401.69978360
13Cell cycle_Homo sapiens_hsa041101.66178311
14Herpes simplex infection_Homo sapiens_hsa051681.65480823
15Measles_Homo sapiens_hsa051621.65324957
16NF-kappa B signaling pathway_Homo sapiens_hsa040641.61479462
17Acute myeloid leukemia_Homo sapiens_hsa052211.60442669
18Osteoclast differentiation_Homo sapiens_hsa043801.59697962
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.56638921
20Hematopoietic cell lineage_Homo sapiens_hsa046401.53238569
21Homologous recombination_Homo sapiens_hsa034401.52559720
22Shigellosis_Homo sapiens_hsa051311.52333139
23Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.51080478
24Chronic myeloid leukemia_Homo sapiens_hsa052201.48720795
25Toxoplasmosis_Homo sapiens_hsa051451.37868815
26Transcriptional misregulation in cancer_Homo sapiens_hsa052021.37283247
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.35989882
28RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.35426681
29Non-homologous end-joining_Homo sapiens_hsa034501.35228274
30RNA transport_Homo sapiens_hsa030131.32844391
31Nucleotide excision repair_Homo sapiens_hsa034201.31557225
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.30525338
33Platelet activation_Homo sapiens_hsa046111.28283575
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.26044252
35Type I diabetes mellitus_Homo sapiens_hsa049401.24390404
36Legionellosis_Homo sapiens_hsa051341.24120836
37Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.21945617
38Jak-STAT signaling pathway_Homo sapiens_hsa046301.21247046
39Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.21056686
40Toll-like receptor signaling pathway_Homo sapiens_hsa046201.20547274
41Renal cell carcinoma_Homo sapiens_hsa052111.19309113
42Hepatitis B_Homo sapiens_hsa051611.18942633
43Small cell lung cancer_Homo sapiens_hsa052221.18071174
44Viral carcinogenesis_Homo sapiens_hsa052031.17989996
45Apoptosis_Homo sapiens_hsa042101.16050326
46Phagosome_Homo sapiens_hsa041451.15170582
47NOD-like receptor signaling pathway_Homo sapiens_hsa046211.14440770
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.13627007
49Influenza A_Homo sapiens_hsa051641.12420272
50Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.12288542
51Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.09159422
52Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.07705979
53Pentose phosphate pathway_Homo sapiens_hsa000301.04248149
54Other glycan degradation_Homo sapiens_hsa005111.03468427
55p53 signaling pathway_Homo sapiens_hsa041151.03032896
56Epstein-Barr virus infection_Homo sapiens_hsa051691.01117479
57T cell receptor signaling pathway_Homo sapiens_hsa046601.00379081
58Non-small cell lung cancer_Homo sapiens_hsa052230.98542761
59Pancreatic cancer_Homo sapiens_hsa052120.97386797
60Pertussis_Homo sapiens_hsa051330.97105951
61Dorso-ventral axis formation_Homo sapiens_hsa043200.96680074
62Fanconi anemia pathway_Homo sapiens_hsa034600.95253994
63Amoebiasis_Homo sapiens_hsa051460.94912029
64Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.94840947
65HTLV-I infection_Homo sapiens_hsa051660.93903582
66Salmonella infection_Homo sapiens_hsa051320.93812718
67Focal adhesion_Homo sapiens_hsa045100.93125743
68N-Glycan biosynthesis_Homo sapiens_hsa005100.91994023
69Pyrimidine metabolism_Homo sapiens_hsa002400.91953464
70African trypanosomiasis_Homo sapiens_hsa051430.90109802
71Endometrial cancer_Homo sapiens_hsa052130.89804658
72mTOR signaling pathway_Homo sapiens_hsa041500.89727577
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.89283734
74AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.88938679
75FoxO signaling pathway_Homo sapiens_hsa040680.88859814
76mRNA surveillance pathway_Homo sapiens_hsa030150.88079011
77Phosphatidylinositol signaling system_Homo sapiens_hsa040700.87949595
78Tuberculosis_Homo sapiens_hsa051520.87628568
79TNF signaling pathway_Homo sapiens_hsa046680.85135695
80RNA degradation_Homo sapiens_hsa030180.85001708
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.84682987
82Viral myocarditis_Homo sapiens_hsa054160.83865405
83Glycosaminoglycan degradation_Homo sapiens_hsa005310.83559054
84Prostate cancer_Homo sapiens_hsa052150.83145988
85VEGF signaling pathway_Homo sapiens_hsa043700.82227250
86Inositol phosphate metabolism_Homo sapiens_hsa005620.80917067
87Malaria_Homo sapiens_hsa051440.80062909
88Chemokine signaling pathway_Homo sapiens_hsa040620.79644175
89Thyroid cancer_Homo sapiens_hsa052160.78884203
90Proteoglycans in cancer_Homo sapiens_hsa052050.78478902
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.78452669
92Choline metabolism in cancer_Homo sapiens_hsa052310.78166330
93Systemic lupus erythematosus_Homo sapiens_hsa053220.77674600
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.74824755
95Asthma_Homo sapiens_hsa053100.74524014
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.73990685
97One carbon pool by folate_Homo sapiens_hsa006700.73625583
98GnRH signaling pathway_Homo sapiens_hsa049120.73614616
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.71783580
100Glioma_Homo sapiens_hsa052140.70374639
101Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.69820828
102ErbB signaling pathway_Homo sapiens_hsa040120.69367436
103Notch signaling pathway_Homo sapiens_hsa043300.67931871
104Colorectal cancer_Homo sapiens_hsa052100.65722206
105MAPK signaling pathway_Homo sapiens_hsa040100.64776736
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64700680
107Sulfur relay system_Homo sapiens_hsa041220.63487404
108Insulin resistance_Homo sapiens_hsa049310.63107816
109Renin-angiotensin system_Homo sapiens_hsa046140.62087493
110MicroRNAs in cancer_Homo sapiens_hsa052060.61675477
111Hepatitis C_Homo sapiens_hsa051600.61054574
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59734157
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59267877
114Bladder cancer_Homo sapiens_hsa052190.59202773
115Lysosome_Homo sapiens_hsa041420.59104377
116Rap1 signaling pathway_Homo sapiens_hsa040150.58705457
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.57432150
118Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56558489
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56483227
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.56302813
121Allograft rejection_Homo sapiens_hsa053300.55631829
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.55526281
123Basal transcription factors_Homo sapiens_hsa030220.55138840
124Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54178874
125Rheumatoid arthritis_Homo sapiens_hsa053230.52831446
126Prolactin signaling pathway_Homo sapiens_hsa049170.52104136
127Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51214107
128HIF-1 signaling pathway_Homo sapiens_hsa040660.50955786
129Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.50869228
130Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.50345584
131Estrogen signaling pathway_Homo sapiens_hsa049150.49176086
132Central carbon metabolism in cancer_Homo sapiens_hsa052300.48364873
133Carbohydrate digestion and absorption_Homo sapiens_hsa049730.45347566
134Pathways in cancer_Homo sapiens_hsa052000.43396998
135Endocytosis_Homo sapiens_hsa041440.42806373
136RNA polymerase_Homo sapiens_hsa030200.40480844
137Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.39553432

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