ANKMY2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)4.95148145
2synaptic vesicle docking involved in exocytosis (GO:0016081)4.74209149
3positive regulation of synapse maturation (GO:0090129)4.61236264
4protein localization to synapse (GO:0035418)4.35168419
5regulation of synaptic vesicle exocytosis (GO:2000300)4.26587509
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.22544016
7vocalization behavior (GO:0071625)4.19652054
8neuron cell-cell adhesion (GO:0007158)4.14369619
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.11276011
10regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.11126030
11neurotransmitter-gated ion channel clustering (GO:0072578)4.00113158
12postsynaptic membrane organization (GO:0001941)3.94115129
13positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.92174827
14regulation of synapse maturation (GO:0090128)3.91217944
15glutamate secretion (GO:0014047)3.87358051
16cullin deneddylation (GO:0010388)3.86371695
17regulation of synaptic vesicle transport (GO:1902803)3.81556445
18inositol phosphate catabolic process (GO:0071545)3.74939474
19regulation of glutamate receptor signaling pathway (GO:1900449)3.73949423
20pyrimidine nucleobase catabolic process (GO:0006208)3.73040247
21striatum development (GO:0021756)3.69062996
22synaptic vesicle maturation (GO:0016188)3.58428907
23protein deneddylation (GO:0000338)3.55886757
24regulation of synapse structural plasticity (GO:0051823)3.52221115
25negative regulation of fibroblast apoptotic process (GO:2000270)3.51550643
26protein localization to cilium (GO:0061512)3.47073783
27positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.41950093
28presynaptic membrane assembly (GO:0097105)3.41677642
29neurotransmitter secretion (GO:0007269)3.35718650
30negative regulation of dendrite morphogenesis (GO:0050774)3.35189353
31response to histamine (GO:0034776)3.33204320
32nucleobase catabolic process (GO:0046113)3.32001708
33long-term synaptic potentiation (GO:0060291)3.29315723
34neuron-neuron synaptic transmission (GO:0007270)3.22881586
35presynaptic membrane organization (GO:0097090)3.22669300
36axonal fasciculation (GO:0007413)3.18637300
37synaptic transmission, glutamatergic (GO:0035249)3.18060210
38phosphorylated carbohydrate dephosphorylation (GO:0046838)3.16185522
39inositol phosphate dephosphorylation (GO:0046855)3.16185522
40ionotropic glutamate receptor signaling pathway (GO:0035235)3.15974543
41synaptic vesicle endocytosis (GO:0048488)3.15316426
42glutamate receptor signaling pathway (GO:0007215)3.13924514
43gamma-aminobutyric acid signaling pathway (GO:0007214)3.13412203
44nonmotile primary cilium assembly (GO:0035058)3.13360154
45positive regulation of mitochondrial fission (GO:0090141)3.10811234
46locomotory exploration behavior (GO:0035641)3.07807609
47negative regulation of synaptic transmission, GABAergic (GO:0032229)3.05689242
48negative regulation of DNA recombination (GO:0045910)3.05147230
49atrial cardiac muscle cell action potential (GO:0086014)3.01360510
50C4-dicarboxylate transport (GO:0015740)2.99578871
51innervation (GO:0060384)2.98671319
52positive regulation of membrane potential (GO:0045838)2.97314286
53G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94136171
54exploration behavior (GO:0035640)2.93867797
55regulation of cilium movement (GO:0003352)2.93751138
56negative regulation of dendrite development (GO:2000171)2.93196812
57startle response (GO:0001964)2.92558233
58synaptic vesicle transport (GO:0048489)2.92536868
59establishment of synaptic vesicle localization (GO:0097480)2.92536868
60intraciliary transport (GO:0042073)2.91574621
61regulation of neurotransmitter secretion (GO:0046928)2.89851342
62regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.89450601
63transferrin transport (GO:0033572)2.88868942
64glycosphingolipid biosynthetic process (GO:0006688)2.88458082
65response to pheromone (GO:0019236)2.86396028
66behavioral fear response (GO:0001662)2.86323300
67behavioral defense response (GO:0002209)2.86323300
68positive regulation of neurotransmitter secretion (GO:0001956)2.86068044
69neuron recognition (GO:0008038)2.85255041
70positive regulation of neurotransmitter transport (GO:0051590)2.84536631
71DNA damage response, detection of DNA damage (GO:0042769)2.84199507
72auditory behavior (GO:0031223)2.81764984
73fatty acid elongation (GO:0030497)2.81739270
74peptidyl-cysteine modification (GO:0018198)2.81132079
75regulation of long-term neuronal synaptic plasticity (GO:0048169)2.80397488
76protein polyglutamylation (GO:0018095)2.78505177
77regulation of excitatory postsynaptic membrane potential (GO:0060079)2.78114678
78DNA integration (GO:0015074)2.77082588
79chaperone-mediated protein transport (GO:0072321)2.76667392
80ubiquinone metabolic process (GO:0006743)2.76483068
81establishment of mitochondrion localization (GO:0051654)2.76282566
82neural tube formation (GO:0001841)2.74777745
83regulation of neuronal synaptic plasticity (GO:0048168)2.73886040
84regulation of vesicle fusion (GO:0031338)2.73265733
85positive regulation of synaptic transmission, GABAergic (GO:0032230)2.72721202
86regulation of synaptic transmission, glutamatergic (GO:0051966)2.72452902
87ribonucleoprotein complex disassembly (GO:0032988)2.72059623
88ubiquinone biosynthetic process (GO:0006744)2.68930287
89cilium morphogenesis (GO:0060271)2.68016068
90dentate gyrus development (GO:0021542)2.67503396
91adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.67159465
92regulation of neurotransmitter transport (GO:0051588)2.66891914
93cholesterol biosynthetic process (GO:0006695)2.66701287
94protein-cofactor linkage (GO:0018065)2.66668412
95GMP metabolic process (GO:0046037)2.65168179
96urinary tract smooth muscle contraction (GO:0014848)2.64562407
97axoneme assembly (GO:0035082)2.63077896
98learning (GO:0007612)2.63060581
99positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.62410179
100trivalent inorganic cation transport (GO:0072512)2.62127167
101ferric iron transport (GO:0015682)2.62127167
102somatic diversification of immune receptors via somatic mutation (GO:0002566)2.61896643
103somatic hypermutation of immunoglobulin genes (GO:0016446)2.61896643
104regulation of feeding behavior (GO:0060259)2.61403620
105regulation of postsynaptic membrane potential (GO:0060078)2.61399061
106neurotransmitter transport (GO:0006836)2.60863158
107sterol biosynthetic process (GO:0016126)2.60193887
108resolution of meiotic recombination intermediates (GO:0000712)2.59359994
109energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.59142159
110ATP hydrolysis coupled proton transport (GO:0015991)2.59142159
111protein neddylation (GO:0045116)2.58430311
112NADH metabolic process (GO:0006734)2.57974642
113mechanosensory behavior (GO:0007638)2.57953528
114fear response (GO:0042596)2.57863047
115epithelial cilium movement (GO:0003351)2.56985140
116guanosine-containing compound biosynthetic process (GO:1901070)2.56937316
117retinal cone cell development (GO:0046549)2.55862698
118regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.55826966
119dopamine transport (GO:0015872)2.55280171
120layer formation in cerebral cortex (GO:0021819)2.54762044
121detection of calcium ion (GO:0005513)2.54730246
122membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.53105010
123neuronal action potential propagation (GO:0019227)2.52901174
124regulation of neurotransmitter levels (GO:0001505)2.52492172
125synapse assembly (GO:0007416)2.51931426
126regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.51233203
127dopamine receptor signaling pathway (GO:0007212)2.51035327
128cilium assembly (GO:0042384)2.50286238
129regulation of synaptic plasticity (GO:0048167)2.49971642
130cilium organization (GO:0044782)2.49948396
131dendrite development (GO:0016358)2.49269035
132retinal ganglion cell axon guidance (GO:0031290)2.49000569
133short-term memory (GO:0007614)2.48816110
134regulation of fibroblast apoptotic process (GO:2000269)2.48641653
135limb bud formation (GO:0060174)2.47703581
136succinate metabolic process (GO:0006105)2.46844683
137organelle disassembly (GO:1903008)2.46439640
138establishment of vesicle localization (GO:0051650)2.46247305
139regulation of glucokinase activity (GO:0033131)2.46073649
140regulation of hexokinase activity (GO:1903299)2.46073649
141long-term memory (GO:0007616)2.45661598
142tricarboxylic acid cycle (GO:0006099)2.45559072
143histone H2A acetylation (GO:0043968)2.44899858
144calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.44662043
145mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.44366241
146gamma-aminobutyric acid transport (GO:0015812)2.43815293
147mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.43188247
148DNA double-strand break processing (GO:0000729)2.42044738
149positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.40075098
150mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.40075098
151regulation of cell communication by electrical coupling (GO:0010649)2.38679160
152regulation of acyl-CoA biosynthetic process (GO:0050812)2.31912163
153cilium movement (GO:0003341)2.31138891
154regulation of mitotic spindle checkpoint (GO:1903504)2.31012932
155regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.31012932
156oxidative phosphorylation (GO:0006119)2.29280509
157regulation of cofactor metabolic process (GO:0051193)2.29201844
158regulation of coenzyme metabolic process (GO:0051196)2.29201844
159regulation of dendritic spine morphogenesis (GO:0061001)2.28226112
160cytoskeleton-dependent intracellular transport (GO:0030705)2.26787208
161isoprenoid biosynthetic process (GO:0008299)2.26758250
162water-soluble vitamin biosynthetic process (GO:0042364)2.26160264
163microtubule-based transport (GO:0010970)2.24889681
164positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.23334315
165intra-S DNA damage checkpoint (GO:0031573)2.23262740
166regulation of microtubule-based movement (GO:0060632)2.22204464
167aldehyde catabolic process (GO:0046185)2.21785219
168proteasome assembly (GO:0043248)2.19734257
169righting reflex (GO:0060013)2.19253937
170regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.18685943
171regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.18534925
172quinone biosynthetic process (GO:1901663)2.18524249
173mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.18358301
174mitochondrial respiratory chain complex I assembly (GO:0032981)2.18358301
175NADH dehydrogenase complex assembly (GO:0010257)2.18358301
176positive regulation of dendritic spine morphogenesis (GO:0061003)2.16902673
177tRNA aminoacylation for protein translation (GO:0006418)2.15168751
178negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.14789638
179L-serine transport (GO:0015825)2.14569195

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.59369508
2GBX2_23144817_ChIP-Seq_PC3_Human3.77767441
3CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons3.56989765
4RBPJ_22232070_ChIP-Seq_NCS_Mouse3.34408336
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.04469067
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.62747056
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.41688811
8ZNF274_21170338_ChIP-Seq_K562_Hela2.40402930
9REST_21632747_ChIP-Seq_MESCs_Mouse2.31939505
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.28615139
11TAF15_26573619_Chip-Seq_HEK293_Human2.09914846
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.08982668
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.04481879
14CTBP2_25329375_ChIP-Seq_LNCAP_Human1.95411340
15THAP11_20581084_ChIP-Seq_MESCs_Mouse1.94507739
16REST_18959480_ChIP-ChIP_MESCs_Mouse1.94367147
17ZFP57_27257070_Chip-Seq_ESCs_Mouse1.92851280
18* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.91289182
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.88132183
20SALL1_21062744_ChIP-ChIP_HESCs_Human1.87215281
21SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.85758753
22IGF1R_20145208_ChIP-Seq_DFB_Human1.84384684
23E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.84291196
24FUS_26573619_Chip-Seq_HEK293_Human1.83136055
25* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.80152844
26YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76728252
27PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.76197285
28RARB_27405468_Chip-Seq_BRAIN_Mouse1.74097754
29SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.70134528
30POU3F2_20337985_ChIP-ChIP_501MEL_Human1.66641727
31* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.65610496
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.63552903
33P300_19829295_ChIP-Seq_ESCs_Human1.63008924
34EST1_17652178_ChIP-ChIP_JURKAT_Human1.61762175
35JARID2_20064375_ChIP-Seq_MESCs_Mouse1.60729786
36RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.59416237
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56521944
38SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.55900069
39SMAD4_21799915_ChIP-Seq_A2780_Human1.54860638
40MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.49363489
41EZH2_27304074_Chip-Seq_ESCs_Mouse1.45222077
42VDR_22108803_ChIP-Seq_LS180_Human1.44730256
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.43735413
44CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.42839602
45* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.42763221
46* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.40780079
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.38854443
48CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38596042
49* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.38359585
50BMI1_23680149_ChIP-Seq_NPCS_Mouse1.38357598
51CDX2_19796622_ChIP-Seq_MESCs_Mouse1.37547686
52ETS1_20019798_ChIP-Seq_JURKAT_Human1.35237780
53SRF_21415370_ChIP-Seq_HL-1_Mouse1.35227166
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34954733
55RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.34848085
56HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.34807085
57* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.33860817
58JARID2_20075857_ChIP-Seq_MESCs_Mouse1.33779945
59PIAS1_25552417_ChIP-Seq_VCAP_Human1.33202466
60* CBP_20019798_ChIP-Seq_JUKART_Human1.31746932
61* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31746932
62SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.31409112
63GABP_17652178_ChIP-ChIP_JURKAT_Human1.31223185
64RNF2_27304074_Chip-Seq_NSC_Mouse1.30760990
65PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29606011
66EWS_26573619_Chip-Seq_HEK293_Human1.28732287
67ER_23166858_ChIP-Seq_MCF-7_Human1.28253970
68JUN_21703547_ChIP-Seq_K562_Human1.28162235
69YY1_21170310_ChIP-Seq_MESCs_Mouse1.27953917
70SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.27591463
71FLI1_27457419_Chip-Seq_LIVER_Mouse1.25569169
72CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.24623351
73ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.24184631
74IRF1_19129219_ChIP-ChIP_H3396_Human1.23415696
75AR_25329375_ChIP-Seq_VCAP_Human1.21396784
76P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17894644
77RNF2_18974828_ChIP-Seq_MESCs_Mouse1.17623359
78EZH2_18974828_ChIP-Seq_MESCs_Mouse1.17623359
79CREB1_15753290_ChIP-ChIP_HEK293T_Human1.17294370
80SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.16747570
81EED_16625203_ChIP-ChIP_MESCs_Mouse1.16611562
82IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15986382
83KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.15236107
84FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.12409551
85TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11234732
86VDR_23849224_ChIP-Seq_CD4+_Human1.10858465
87OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10848185
88DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.10615773
89NANOG_18555785_Chip-Seq_ESCs_Mouse1.10244987
90SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.09675195
91TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07911075
92CBX2_27304074_Chip-Seq_ESCs_Mouse1.07669689
93* MYC_18940864_ChIP-ChIP_HL60_Human1.07662787
94CIITA_25753668_ChIP-Seq_RAJI_Human1.07651589
95CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06863513
96TAL1_26923725_Chip-Seq_HPCs_Mouse1.05912044
97ELK1_19687146_ChIP-ChIP_HELA_Human1.05566773
98GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05187086
99RNF2_27304074_Chip-Seq_ESCs_Mouse1.05172016
100GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05147460
101SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.05068177
102* FOXP3_21729870_ChIP-Seq_TREG_Human1.04982081
103SMAD3_21741376_ChIP-Seq_EPCs_Human1.04231868
104SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.04040290
105PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03446970
106UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02380698
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01822891
108TCF4_22108803_ChIP-Seq_LS180_Human1.01316744
109DCP1A_22483619_ChIP-Seq_HELA_Human1.01084383
110EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00489142
111AR_21572438_ChIP-Seq_LNCaP_Human1.00192548
112GABP_19822575_ChIP-Seq_HepG2_Human0.98916837
113NANOG_19829295_ChIP-Seq_ESCs_Human0.98461631
114SOX2_19829295_ChIP-Seq_ESCs_Human0.98461631
115POU5F1_16153702_ChIP-ChIP_HESCs_Human0.98350468
116RUNX2_22187159_ChIP-Seq_PCA_Human0.98153117
117KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.97914319
118TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97912629
119EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.97877321
120EZH2_27294783_Chip-Seq_NPCs_Mouse0.97404399
121P53_22387025_ChIP-Seq_ESCs_Mouse0.97045994
122ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.96741578
123WT1_19549856_ChIP-ChIP_CCG9911_Human0.96697173
124PADI4_21655091_ChIP-ChIP_MCF-7_Human0.96242709
125REST_19997604_ChIP-ChIP_NEURONS_Mouse0.95624468
126* SOX9_26525672_Chip-Seq_HEART_Mouse0.93638731
127SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92585746
128* SOX2_21211035_ChIP-Seq_LN229_Gbm0.92323111
129TP53_22573176_ChIP-Seq_HFKS_Human0.91659119
130MTF2_20144788_ChIP-Seq_MESCs_Mouse0.91098000
131PCGF2_27294783_Chip-Seq_ESCs_Mouse0.90836073
132EZH2_27294783_Chip-Seq_ESCs_Mouse0.90808575
133TCF4_23295773_ChIP-Seq_U87_Human0.89382042
134MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88951659
135* STAT3_23295773_ChIP-Seq_U87_Human0.87592989

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.81101552
2MP0003880_abnormal_central_pattern3.71813569
3MP0003787_abnormal_imprinting3.65913945
4MP0003122_maternal_imprinting3.11518471
5MP0001984_abnormal_olfaction3.07050451
6MP0003635_abnormal_synaptic_transmissio2.97216915
7MP0001188_hyperpigmentation2.93095684
8MP0002063_abnormal_learning/memory/cond2.62616982
9MP0002102_abnormal_ear_morphology2.60455487
10MP0009745_abnormal_behavioral_response2.54782397
11MP0002822_catalepsy2.42164599
12MP0008877_abnormal_DNA_methylation2.36469858
13MP0003121_genomic_imprinting2.36038845
14MP0001968_abnormal_touch/_nociception2.31747617
15MP0002572_abnormal_emotion/affect_behav2.23958341
16MP0005423_abnormal_somatic_nervous2.22810795
17MP0005646_abnormal_pituitary_gland2.19856531
18MP0002064_seizures2.15776057
19MP0005394_taste/olfaction_phenotype2.10376201
20MP0005499_abnormal_olfactory_system2.10376201
21MP0009046_muscle_twitch2.10132875
22MP0002736_abnormal_nociception_after2.09364703
23MP0002734_abnormal_mechanical_nocicepti2.06550473
24MP0002638_abnormal_pupillary_reflex2.01928641
25MP0006276_abnormal_autonomic_nervous2.00455011
26MP0004270_analgesia1.92781438
27MP0002272_abnormal_nervous_system1.92202124
28MP0009780_abnormal_chondrocyte_physiolo1.89034528
29MP0001529_abnormal_vocalization1.88579021
30MP0006292_abnormal_olfactory_placode1.85066688
31MP0003183_abnormal_peptide_metabolism1.81813107
32MP0005645_abnormal_hypothalamus_physiol1.80053515
33MP0008789_abnormal_olfactory_epithelium1.77191533
34MP0003123_paternal_imprinting1.75588530
35MP0001486_abnormal_startle_reflex1.75173920
36MP0002184_abnormal_innervation1.72460927
37MP0009697_abnormal_copulation1.69394927
38MP0005551_abnormal_eye_electrophysiolog1.67036306
39MP0002557_abnormal_social/conspecific_i1.67018987
40MP0002067_abnormal_sensory_capabilities1.65953637
41MP0002876_abnormal_thyroid_physiology1.65474450
42MP0001501_abnormal_sleep_pattern1.62166314
43MP0002837_dystrophic_cardiac_calcinosis1.60796354
44MP0010386_abnormal_urinary_bladder1.58337713
45MP0001502_abnormal_circadian_rhythm1.53048676
46MP0002735_abnormal_chemical_nociception1.52510822
47MP0004811_abnormal_neuron_physiology1.51729560
48MP0000778_abnormal_nervous_system1.47304779
49MP0000647_abnormal_sebaceous_gland1.46071838
50MP0005386_behavior/neurological_phenoty1.44426648
51MP0004924_abnormal_behavior1.44426648
52MP0005187_abnormal_penis_morphology1.38584583
53MP0004084_abnormal_cardiac_muscle1.36934401
54MP0001986_abnormal_taste_sensitivity1.36225759
55MP0003879_abnormal_hair_cell1.36065292
56MP0001970_abnormal_pain_threshold1.31042155
57MP0000631_abnormal_neuroendocrine_gland1.28251798
58MP0001440_abnormal_grooming_behavior1.25988598
59MP0006072_abnormal_retinal_apoptosis1.25075365
60MP0002733_abnormal_thermal_nociception1.24594084
61MP0001293_anophthalmia1.24023218
62MP0004133_heterotaxia1.22912321
63MP0002233_abnormal_nose_morphology1.22542583
64MP0002909_abnormal_adrenal_gland1.20025022
65MP0002234_abnormal_pharynx_morphology1.17981830
66MP0003195_calcinosis1.16744026
67MP0001905_abnormal_dopamine_level1.12949909
68MP0008569_lethality_at_weaning1.11764673
69MP0002882_abnormal_neuron_morphology1.09301181
70MP0001299_abnormal_eye_distance/1.09198915
71MP0004142_abnormal_muscle_tone1.08748044
72MP0008775_abnormal_heart_ventricle1.07738305
73MP0002090_abnormal_vision1.07208439
74MP0002751_abnormal_autonomic_nervous1.06719773
75MP0003567_abnormal_fetal_cardiomyocyte1.05528856
76MP0003221_abnormal_cardiomyocyte_apopto1.04684806
77MP0003718_maternal_effect1.03361114
78MP0004145_abnormal_muscle_electrophysio0.99897276
79MP0000569_abnormal_digit_pigmentation0.99894415
80MP0000751_myopathy0.99084655
81MP0008995_early_reproductive_senescence0.98055197
82MP0002066_abnormal_motor_capabilities/c0.96820421
83MP0008058_abnormal_DNA_repair0.95518251
84MP0003385_abnormal_body_wall0.95247477
85MP0006036_abnormal_mitochondrial_physio0.92866355
86MP0008007_abnormal_cellular_replicative0.91924172
87MP0000681_abnormal_thyroid_gland0.91417286
88MP0002163_abnormal_gland_morphology0.90506662
89MP0000955_abnormal_spinal_cord0.90502953
90MP0002152_abnormal_brain_morphology0.88240763
91MP0005253_abnormal_eye_physiology0.85596011
92MP0004036_abnormal_muscle_relaxation0.85220763
93MP0003937_abnormal_limbs/digits/tail_de0.84797457
94MP0000372_irregular_coat_pigmentation0.82897803
95MP0000427_abnormal_hair_cycle0.82712430
96MP0003890_abnormal_embryonic-extraembry0.81554635
97MP0008875_abnormal_xenobiotic_pharmacok0.81094916
98MP0003283_abnormal_digestive_organ0.79992690
99MP0005248_abnormal_Harderian_gland0.79156344
100MP0001963_abnormal_hearing_physiology0.78159081
101MP0000749_muscle_degeneration0.76931284
102MP0002752_abnormal_somatic_nervous0.75497772
103MP0001664_abnormal_digestion0.75236959
104MP0005367_renal/urinary_system_phenotyp0.75062992
105MP0000516_abnormal_urinary_system0.75062992
106MP0000534_abnormal_ureter_morphology0.74929351
107MP0003755_abnormal_palate_morphology0.73709073
108MP0005391_vision/eye_phenotype0.73644770
109MP0004085_abnormal_heartbeat0.73476686
110MP0001929_abnormal_gametogenesis0.73189964
111MP0005409_darkened_coat_color0.72713120
112MP0003861_abnormal_nervous_system0.72697453
113MP0002938_white_spotting0.72139410
114MP0002069_abnormal_eating/drinking_beha0.71747888
115MP0001177_atelectasis0.71576033
116MP0005171_absent_coat_pigmentation0.71424640
117MP0004043_abnormal_pH_regulation0.70987258
118MP0004215_abnormal_myocardial_fiber0.70754734
119MP0003119_abnormal_digestive_system0.70513798
120MP0004885_abnormal_endolymph0.69084135
121MP0002160_abnormal_reproductive_system0.68748575
122MP0006035_abnormal_mitochondrial_morpho0.68574201
123MP0003786_premature_aging0.66832089
124MP0002229_neurodegeneration0.66459368
125MP0000013_abnormal_adipose_tissue0.62718306
126MP0005379_endocrine/exocrine_gland_phen0.61227299
127MP0002396_abnormal_hematopoietic_system0.61220235
128MP0002095_abnormal_skin_pigmentation0.61027331
129MP0005075_abnormal_melanosome_morpholog0.60921270
130MP0003137_abnormal_impulse_conducting0.59533034
131MP0000015_abnormal_ear_pigmentation0.58721059
132MP0008004_abnormal_stomach_pH0.58169063
133MP0004147_increased_porphyrin_level0.56504563

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.32524377
2Abnormal hair whorl (HP:0010721)4.26736104
3Febrile seizures (HP:0002373)4.21346049
4Epileptic encephalopathy (HP:0200134)4.07428605
5Visual hallucinations (HP:0002367)3.93529977
6Gait imbalance (HP:0002141)3.45309742
7Nephrogenic diabetes insipidus (HP:0009806)3.25850953
8Atonic seizures (HP:0010819)3.18549298
9Congenital primary aphakia (HP:0007707)3.14380250
10Cortical dysplasia (HP:0002539)3.11549172
11Medial flaring of the eyebrow (HP:0010747)3.07084717
12Focal seizures (HP:0007359)2.95812056
13Failure to thrive in infancy (HP:0001531)2.94246839
14Type II lissencephaly (HP:0007260)2.90002109
15Hypoglycemic seizures (HP:0002173)2.89741218
16Birth length less than 3rd percentile (HP:0003561)2.89692067
17Exercise-induced muscle cramps (HP:0003710)2.89014681
18Absence seizures (HP:0002121)2.85185523
19Abnormality of the labia minora (HP:0012880)2.83021101
20Myokymia (HP:0002411)2.81217060
21Lissencephaly (HP:0001339)2.77243894
22Progressive cerebellar ataxia (HP:0002073)2.71953393
23Hypoglycemic coma (HP:0001325)2.69880740
24Acute encephalopathy (HP:0006846)2.69824077
25Abnormality of glycolysis (HP:0004366)2.68968438
26Increased serum pyruvate (HP:0003542)2.68812394
27Hypothermia (HP:0002045)2.62049279
28Poor coordination (HP:0002370)2.60568907
29Dialeptic seizures (HP:0011146)2.60338503
30Severe visual impairment (HP:0001141)2.55001580
31Methylmalonic acidemia (HP:0002912)2.54002381
32Congenital stationary night blindness (HP:0007642)2.53235686
33Anterior segment dysgenesis (HP:0007700)2.49452017
34Hyperventilation (HP:0002883)2.48289166
35Pancreatic cysts (HP:0001737)2.48283120
36Protruding tongue (HP:0010808)2.47909780
37Hyperinsulinemic hypoglycemia (HP:0000825)2.47397468
38Neuroblastoma (HP:0003006)2.46733480
39Primitive neuroectodermal tumor (HP:0030065)2.46733480
40Neuroblastic tumors (HP:0004376)2.46733480
41Peripheral primitive neuroectodermal neoplasm (HP:0030067)2.46733480
42Poor suck (HP:0002033)2.42062968
43Progressive inability to walk (HP:0002505)2.40117196
44Occipital encephalocele (HP:0002085)2.39964697
45Heterochromia iridis (HP:0001100)2.39025609
46Cerebellar dysplasia (HP:0007033)2.37005959
47Unsteady gait (HP:0002317)2.35513126
48Hepatic necrosis (HP:0002605)2.34247558
49Polyphagia (HP:0002591)2.32424372
50Tubulointerstitial nephritis (HP:0001970)2.31284871
51Ependymoma (HP:0002888)2.30698207
52True hermaphroditism (HP:0010459)2.29309260
53Pancreatic fibrosis (HP:0100732)2.27586289
54Medulloblastoma (HP:0002885)2.25652590
55Postaxial hand polydactyly (HP:0001162)2.25477915
56Inability to walk (HP:0002540)2.22389866
57Hypoplasia of the brainstem (HP:0002365)2.22345358
58Aplasia/Hypoplasia of the brainstem (HP:0007362)2.22345358
59Agnosia (HP:0010524)2.19802434
60Epileptiform EEG discharges (HP:0011182)2.17837074
61Aplastic anemia (HP:0001915)2.16992702
62Rimmed vacuoles (HP:0003805)2.13908918
63Degeneration of anterior horn cells (HP:0002398)2.13099588
64Abnormality of the anterior horn cell (HP:0006802)2.13099588
65Limb dystonia (HP:0002451)2.11873550
66Abnormal eating behavior (HP:0100738)2.11389497
67Decreased testicular size (HP:0008734)2.09129887
68Vaginal atresia (HP:0000148)2.08339659
69Broad-based gait (HP:0002136)2.06302555
70Genital tract atresia (HP:0001827)2.06055815
71EEG with generalized epileptiform discharges (HP:0011198)2.05084492
72Shoulder girdle muscle weakness (HP:0003547)2.04917791
73Absent speech (HP:0001344)2.04482390
74Anxiety (HP:0000739)2.03554885
75Bifid tongue (HP:0010297)2.01451713
76Myoglobinuria (HP:0002913)1.98857479
77Left ventricular hypertrophy (HP:0001712)1.98435889
78Cerebral edema (HP:0002181)1.98117904
79Macroglossia (HP:0000158)1.97956940
80Generalized tonic-clonic seizures (HP:0002069)1.97190942
81Postaxial foot polydactyly (HP:0001830)1.97065289
82Nephronophthisis (HP:0000090)1.96623784
83Prostate neoplasm (HP:0100787)1.96057873
84Bundle branch block (HP:0011710)1.95655002
85Decreased activity of mitochondrial respiratory chain (HP:0008972)1.94950903
86Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.94950903
87Aplasia/Hypoplasia of the tongue (HP:0010295)1.94585556
88Drooling (HP:0002307)1.93859143
89Excessive salivation (HP:0003781)1.93859143
903-Methylglutaconic aciduria (HP:0003535)1.93500541
91Narrow nasal bridge (HP:0000446)1.93223213
92Papillary thyroid carcinoma (HP:0002895)1.93054449
93Broad foot (HP:0001769)1.92113178
94Neuroendocrine neoplasm (HP:0100634)1.91643063
95Abnormality of midbrain morphology (HP:0002418)1.91322318
96Molar tooth sign on MRI (HP:0002419)1.91322318
97CNS hypomyelination (HP:0003429)1.90773613
98Central scotoma (HP:0000603)1.90465714
99Impaired smooth pursuit (HP:0007772)1.90392871
100Chronic hepatic failure (HP:0100626)1.89387431
101Muscular hypotonia of the trunk (HP:0008936)1.89202102
102Cerebral hypomyelination (HP:0006808)1.87815648
103Scrotal hypoplasia (HP:0000046)1.87798905
104Sclerocornea (HP:0000647)1.87147292
105Mitochondrial inheritance (HP:0001427)1.87132268
106Neoplasm of the adrenal gland (HP:0100631)1.86522778
107Truncal ataxia (HP:0002078)1.85512474
108Specific learning disability (HP:0001328)1.85274621
109Optic nerve hypoplasia (HP:0000609)1.84442977
110Micropenis (HP:0000054)1.84247653
111Hepatocellular necrosis (HP:0001404)1.83640709
112Cholecystitis (HP:0001082)1.82796487
113Abnormal gallbladder physiology (HP:0012438)1.82796487
114Amblyopia (HP:0000646)1.82685957
115Oculomotor apraxia (HP:0000657)1.82677037
116Increased hepatocellular lipid droplets (HP:0006565)1.82656263
117Atrophy/Degeneration involving motor neurons (HP:0007373)1.81607771
118Neoplasm of the adrenal cortex (HP:0100641)1.81099666
119Hypsarrhythmia (HP:0002521)1.80595377
120Narrow forehead (HP:0000341)1.80336218
121Poor eye contact (HP:0000817)1.78718527
122Pheochromocytoma (HP:0002666)1.78305457
123Renal cortical cysts (HP:0000803)1.78019976
124Buphthalmos (HP:0000557)1.77683831
125Acute necrotizing encephalopathy (HP:0006965)1.77074016
126Gonadotropin excess (HP:0000837)1.76105589
127Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.74953270
128Progressive macrocephaly (HP:0004481)1.74809784
129Lactic acidosis (HP:0003128)1.73830525
130Neoplasm of the peripheral nervous system (HP:0100007)1.73558610
131Increased CSF lactate (HP:0002490)1.73537824
132Abnormal mitochondria in muscle tissue (HP:0008316)1.73414505
133Action tremor (HP:0002345)1.73231046
134Abnormality of alanine metabolism (HP:0010916)1.73158902
135Hyperalaninemia (HP:0003348)1.73158902
136Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.73158902
137Hyperglycinemia (HP:0002154)1.71787850
138Oligomenorrhea (HP:0000876)1.71704738
139Methylmalonic aciduria (HP:0012120)1.70951214
140Thyroid carcinoma (HP:0002890)1.69650826
141Neuroectodermal neoplasm (HP:0030061)1.69284341
142Neuroepithelial neoplasm (HP:0030063)1.69284341
143Nervous tissue neoplasm (HP:0030060)1.69284341
144Retinal dysplasia (HP:0007973)1.69254722
145Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.68678709
146Degeneration of the lateral corticospinal tracts (HP:0002314)1.68678709
147Exercise intolerance (HP:0003546)1.67053770
148Glioma (HP:0009733)1.66795924
149Aplasia/Hypoplasia of the lens (HP:0008063)1.66779879
150Increased serum lactate (HP:0002151)1.66309283
151Abnormality of the astrocytes (HP:0100707)1.65241316
152Astrocytoma (HP:0009592)1.65241316
153Intellectual disability, severe (HP:0010864)1.64778434
154Hemiparesis (HP:0001269)1.64535449
155X-linked dominant inheritance (HP:0001423)1.64092537
156Dyskinesia (HP:0100660)1.63578534
157Supernumerary spleens (HP:0009799)1.63396667

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.86887542
2PIK3CG3.69472021
3AKT33.40565190
4MAP3K123.34514267
5TRIM283.34423299
6SIK33.31373791
7MAP4K23.20665958
8NTRK32.70522468
9MAP2K72.65895832
10MARK12.58603632
11PRPF4B2.52446809
12MINK12.31289060
13SGK22.27336262
14EPHA42.12276427
15TSSK62.10324646
16ERBB32.05719759
17NEK12.03730696
18PLK22.02945413
19CDK81.75440366
20DAPK11.70488255
21MAP3K41.66258706
22MAPK131.64527508
23PBK1.63529741
24CCNB11.63314735
25FRK1.63237426
26STK161.56131841
27PRKD31.55371991
28OBSCN1.54892768
29NME11.49417075
30SGK4941.45716996
31SGK2231.45716996
32CSNK1G21.44290906
33MST41.42362006
34SGK31.41206680
35CSNK1G31.41194068
36PLK31.39261745
37NTRK21.39128286
38TTK1.33186962
39CSNK1G11.30078963
40MKNK11.25564354
41CSNK1A1L1.17357887
42BMPR21.13981802
43BCR1.10949426
44KSR11.09885542
45DAPK21.08478378
46STK241.08433199
47ZAK1.07054254
48SRPK11.05510719
49TNIK1.03801025
50LIMK11.03600746
51MAP3K91.03517693
52RPS6KA41.00849009
53PINK10.99880313
54PRKCG0.97929758
55ACVR1B0.96235434
56ERBB40.94759917
57BRSK10.94422272
58LMTK20.91364584
59WNK30.91299643
60PLK40.90733623
61FLT30.90703476
62TAOK20.90513626
63CAMKK20.88086098
64BRAF0.87762569
65CDK190.87549320
66MKNK20.85459065
67MYLK0.83789958
68STK38L0.81048196
69BUB10.76067772
70UHMK10.75403408
71CDK50.74673089
72GRK50.74140131
73MAP2K40.73740049
74PRKCH0.73413008
75RPS6KA20.73279621
76BCKDK0.72421941
77RIPK40.71949295
78KIT0.71789888
79OXSR10.70122106
80RPS6KB10.69967135
81DYRK1A0.68520640
82NEK60.66670923
83CDK180.63992171
84ARAF0.63947409
85ADRBK20.63917875
86MATK0.63471615
87PIK3CA0.62850408
88YES10.62714374
89BRSK20.61942763
90PRKCE0.61708984
91EIF2AK10.61073057
92CDK30.60922753
93PAK60.59352724
94FER0.59130025
95DYRK30.58983971
96CAMK2G0.56473037
97STK390.56266317
98BMPR1B0.55954194
99SCYL20.54132048
100CAMK2A0.52104308
101PHKG20.51837324
102PHKG10.51837324
103MAPK70.51129231
104PNCK0.50605651
105PKN10.49753753
106SIK20.49446821
107EPHA30.48710288
108ATM0.46767498
109CSNK1E0.46392315
110DYRK1B0.45284654
111CDK150.43661758
112PLK10.43181902
113PAK30.42975023
114PRKACB0.41515340
115EIF2AK30.41470307
116PRKACA0.41325382
117CAMK2D0.41266351
118CAMKK10.41028218
119VRK10.40862496
120SGK10.40853585
121CAMK2B0.40282440
122CDK140.39977016
123DYRK20.39392763
124PDK20.39168055
125STK380.38827488
126TESK10.38055287
127CDK11A0.37136881
128CSNK1A10.36412408
129MAP3K60.36022200
130MAP3K50.34340253
131MAP2K60.34069489
132NTRK10.33491189
133PRKAA10.33239421
134ADRBK10.31920113
135RAF10.31078532
136TXK0.30806526
137WEE10.30181707
138ATR0.29978374
139RPS6KC10.28104400
140RPS6KL10.28104400
141CHEK20.27519308

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.95340385
2Synaptic vesicle cycle_Homo sapiens_hsa047213.75251385
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.72076348
4Fatty acid elongation_Homo sapiens_hsa000622.62636841
5Olfactory transduction_Homo sapiens_hsa047402.55380508
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.50479739
7GABAergic synapse_Homo sapiens_hsa047272.45663212
8Propanoate metabolism_Homo sapiens_hsa006402.42744267
9Collecting duct acid secretion_Homo sapiens_hsa049662.31908236
10Morphine addiction_Homo sapiens_hsa050322.30733158
11Circadian entrainment_Homo sapiens_hsa047132.21174317
12Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.07461127
13Butanoate metabolism_Homo sapiens_hsa006502.06104244
14Steroid biosynthesis_Homo sapiens_hsa001001.96889959
15Amphetamine addiction_Homo sapiens_hsa050311.90698635
16Vibrio cholerae infection_Homo sapiens_hsa051101.89568365
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.83845191
18Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.80375693
19Dopaminergic synapse_Homo sapiens_hsa047281.77861224
20Long-term potentiation_Homo sapiens_hsa047201.73597702
21Taste transduction_Homo sapiens_hsa047421.69134087
22Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.68639389
23Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.67753765
24Glutamatergic synapse_Homo sapiens_hsa047241.66463182
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.65431969
26Insulin secretion_Homo sapiens_hsa049111.63713358
27Cholinergic synapse_Homo sapiens_hsa047251.59707030
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56400499
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54921961
30Serotonergic synapse_Homo sapiens_hsa047261.50060066
31Pyruvate metabolism_Homo sapiens_hsa006201.49951863
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.46979420
33Oxidative phosphorylation_Homo sapiens_hsa001901.39416701
34Non-homologous end-joining_Homo sapiens_hsa034501.36931252
35Aldosterone synthesis and secretion_Homo sapiens_hsa049251.35307868
36Phototransduction_Homo sapiens_hsa047441.33580617
37RNA polymerase_Homo sapiens_hsa030201.33571808
38Carbon metabolism_Homo sapiens_hsa012001.31828907
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28831665
40Proteasome_Homo sapiens_hsa030501.28789896
41Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25960046
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.22701495
43Circadian rhythm_Homo sapiens_hsa047101.22584825
44Endometrial cancer_Homo sapiens_hsa052131.22489608
45Parkinsons disease_Homo sapiens_hsa050121.22264606
46Cocaine addiction_Homo sapiens_hsa050301.19271146
47Fatty acid metabolism_Homo sapiens_hsa012121.15604540
48Peroxisome_Homo sapiens_hsa041461.13096889
49Mismatch repair_Homo sapiens_hsa034301.12390882
50Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.11372199
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.09051426
52Oxytocin signaling pathway_Homo sapiens_hsa049211.08456994
53Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.08249369
54Oocyte meiosis_Homo sapiens_hsa041141.06489702
55Renin secretion_Homo sapiens_hsa049241.06422108
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.05511046
57Salivary secretion_Homo sapiens_hsa049701.04810234
58Nitrogen metabolism_Homo sapiens_hsa009101.04107575
59SNARE interactions in vesicular transport_Homo sapiens_hsa041301.02348161
60Calcium signaling pathway_Homo sapiens_hsa040201.01989411
61Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.00752554
62Cysteine and methionine metabolism_Homo sapiens_hsa002700.99455417
63Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99084422
64Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97539827
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.96589975
66Huntingtons disease_Homo sapiens_hsa050160.96515371
67N-Glycan biosynthesis_Homo sapiens_hsa005100.96061880
68Biosynthesis of amino acids_Homo sapiens_hsa012300.95696168
69Protein export_Homo sapiens_hsa030600.94852460
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94124153
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.91804705
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91434894
73Long-term depression_Homo sapiens_hsa047300.91188679
74Vitamin B6 metabolism_Homo sapiens_hsa007500.90229970
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.88618122
76Colorectal cancer_Homo sapiens_hsa052100.88448171
77Gap junction_Homo sapiens_hsa045400.88109505
78Alzheimers disease_Homo sapiens_hsa050100.87155094
79Cardiac muscle contraction_Homo sapiens_hsa042600.85441916
80Purine metabolism_Homo sapiens_hsa002300.84071407
81Glioma_Homo sapiens_hsa052140.81830388
82Maturity onset diabetes of the young_Homo sapiens_hsa049500.81687235
83mRNA surveillance pathway_Homo sapiens_hsa030150.81409621
84Type II diabetes mellitus_Homo sapiens_hsa049300.80695978
85Gastric acid secretion_Homo sapiens_hsa049710.80201311
86Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.79861709
87Fructose and mannose metabolism_Homo sapiens_hsa000510.79815747
88Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77939132
89Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76752255
90Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.75831760
91Fatty acid degradation_Homo sapiens_hsa000710.74306404
92Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73800753
93Inositol phosphate metabolism_Homo sapiens_hsa005620.73619102
94Spliceosome_Homo sapiens_hsa030400.73282963
95Arginine and proline metabolism_Homo sapiens_hsa003300.73183614
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72410122
97beta-Alanine metabolism_Homo sapiens_hsa004100.72144086
98cAMP signaling pathway_Homo sapiens_hsa040240.71155912
99Type I diabetes mellitus_Homo sapiens_hsa049400.70004638
100RNA degradation_Homo sapiens_hsa030180.69447611
101cGMP-PKG signaling pathway_Homo sapiens_hsa040220.68138995
102Metabolic pathways_Homo sapiens_hsa011000.66472294
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.66188825
104Estrogen signaling pathway_Homo sapiens_hsa049150.66003093
105RNA transport_Homo sapiens_hsa030130.65756524
106Cell cycle_Homo sapiens_hsa041100.65509491
107Alcoholism_Homo sapiens_hsa050340.62810171
108ErbB signaling pathway_Homo sapiens_hsa040120.62160972
109GnRH signaling pathway_Homo sapiens_hsa049120.61946532
110Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61576378
111Galactose metabolism_Homo sapiens_hsa000520.61467857
112Non-small cell lung cancer_Homo sapiens_hsa052230.61275905
113Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60401459
114Selenocompound metabolism_Homo sapiens_hsa004500.60170703
115Basal transcription factors_Homo sapiens_hsa030220.59693158
116Base excision repair_Homo sapiens_hsa034100.59079354
117Nucleotide excision repair_Homo sapiens_hsa034200.58230736
118Central carbon metabolism in cancer_Homo sapiens_hsa052300.57783766
119Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56339371
120Glutathione metabolism_Homo sapiens_hsa004800.56211419
121Fanconi anemia pathway_Homo sapiens_hsa034600.55415250
122Pyrimidine metabolism_Homo sapiens_hsa002400.55008515
123Melanoma_Homo sapiens_hsa052180.54646707
124mTOR signaling pathway_Homo sapiens_hsa041500.54010186
125Tryptophan metabolism_Homo sapiens_hsa003800.53326923
126Homologous recombination_Homo sapiens_hsa034400.50156997
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49650349
128Regulation of autophagy_Homo sapiens_hsa041400.49453470
129Folate biosynthesis_Homo sapiens_hsa007900.49424903
130Melanogenesis_Homo sapiens_hsa049160.48588070
131Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47840117
132Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47015309
133Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45703878
134Neurotrophin signaling pathway_Homo sapiens_hsa047220.44953129
135Sulfur metabolism_Homo sapiens_hsa009200.42144353
136Glucagon signaling pathway_Homo sapiens_hsa049220.41851500
137Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41777740
138Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41501050
139Arginine biosynthesis_Homo sapiens_hsa002200.41249385
140Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.39962580
141Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38862046
142Ether lipid metabolism_Homo sapiens_hsa005650.38552504
143Hippo signaling pathway_Homo sapiens_hsa043900.37340250
144Rheumatoid arthritis_Homo sapiens_hsa053230.36145037
145Axon guidance_Homo sapiens_hsa043600.35734002
146Phagosome_Homo sapiens_hsa041450.34249768
147Vascular smooth muscle contraction_Homo sapiens_hsa042700.33953080

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