ALG3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.62305311
2ribosomal small subunit assembly (GO:0000028)5.21897658
3nucleobase biosynthetic process (GO:0046112)4.90099192
4DNA strand elongation involved in DNA replication (GO:0006271)4.85049114
5telomere maintenance via semi-conservative replication (GO:0032201)4.78719826
6proteasome assembly (GO:0043248)4.74556952
7purine nucleobase biosynthetic process (GO:0009113)4.72160320
8DNA strand elongation (GO:0022616)4.60289779
9formation of translation preinitiation complex (GO:0001731)4.44419286
10maturation of SSU-rRNA (GO:0030490)4.39788450
11DNA replication initiation (GO:0006270)4.25232600
12L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.23314189
13IMP biosynthetic process (GO:0006188)4.19393029
14protein maturation by protein folding (GO:0022417)4.13152400
15ribosomal large subunit biogenesis (GO:0042273)4.11635536
16viral transcription (GO:0019083)4.10188025
17telomere maintenance via recombination (GO:0000722)4.07607660
18translational termination (GO:0006415)4.04005805
19DNA replication checkpoint (GO:0000076)4.03710173
20ribosomal small subunit biogenesis (GO:0042274)3.96936987
21pseudouridine synthesis (GO:0001522)3.93468917
22negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.92719471
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.88343833
24ribonucleoprotein complex biogenesis (GO:0022613)3.87007699
25cotranslational protein targeting to membrane (GO:0006613)3.83338906
26deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.83009452
27ribosome biogenesis (GO:0042254)3.79705467
28translational elongation (GO:0006414)3.78286717
29protein targeting to ER (GO:0045047)3.78032318
30transcription elongation from RNA polymerase III promoter (GO:0006385)3.76192411
31termination of RNA polymerase III transcription (GO:0006386)3.76192411
32anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.71465506
33positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.71123740
34telomere maintenance via telomere lengthening (GO:0010833)3.70710740
35spliceosomal snRNP assembly (GO:0000387)3.70313660
36mitotic recombination (GO:0006312)3.70188565
37translational initiation (GO:0006413)3.69198284
38regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.68108591
39protein localization to endoplasmic reticulum (GO:0070972)3.66296576
40protein deneddylation (GO:0000338)3.65910127
41rRNA modification (GO:0000154)3.63818730
42cullin deneddylation (GO:0010388)3.63369798
43IMP metabolic process (GO:0046040)3.62180235
44DNA unwinding involved in DNA replication (GO:0006268)3.60053767
45negative regulation of ligase activity (GO:0051352)3.59440410
46negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.59440410
47rRNA processing (GO:0006364)3.59264216
48amino acid salvage (GO:0043102)3.58140467
49L-methionine salvage (GO:0071267)3.58140467
50L-methionine biosynthetic process (GO:0071265)3.58140467
51establishment of protein localization to endoplasmic reticulum (GO:0072599)3.57787242
52translation (GO:0006412)3.56851138
53nucleotide-excision repair, DNA gap filling (GO:0006297)3.56062106
54ribosome assembly (GO:0042255)3.55117646
55regulation of cellular amino acid metabolic process (GO:0006521)3.52979366
56DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.52846693
57transcription-coupled nucleotide-excision repair (GO:0006283)3.52232879
58intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.50274780
59signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.50274780
60signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.47667855
61signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.47667855
62signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.47667855
63CENP-A containing nucleosome assembly (GO:0034080)3.46544275
64establishment of integrated proviral latency (GO:0075713)3.46341587
65ATP synthesis coupled proton transport (GO:0015986)3.45763190
66energy coupled proton transport, down electrochemical gradient (GO:0015985)3.45763190
67cellular component biogenesis (GO:0044085)3.44937561
68rRNA metabolic process (GO:0016072)3.42733732
69protein targeting to mitochondrion (GO:0006626)3.39508329
70chaperone-mediated protein transport (GO:0072321)3.39404079
71mitochondrial respiratory chain complex I assembly (GO:0032981)3.38324893
72NADH dehydrogenase complex assembly (GO:0010257)3.38324893
73mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.38324893
74antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.36683271
75signal transduction involved in DNA integrity checkpoint (GO:0072401)3.36590617
76signal transduction involved in DNA damage checkpoint (GO:0072422)3.36590617
777-methylguanosine mRNA capping (GO:0006370)3.35019113
78mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.31793203
79nucleobase-containing small molecule interconversion (GO:0015949)3.31432431
80signal transduction involved in cell cycle checkpoint (GO:0072395)3.30446094
81RNA capping (GO:0036260)3.29977811
827-methylguanosine RNA capping (GO:0009452)3.29977811
83chromatin remodeling at centromere (GO:0031055)3.29908743
84GDP-mannose metabolic process (GO:0019673)3.27481504
85G1/S transition of mitotic cell cycle (GO:0000082)3.24356779
86cell cycle G1/S phase transition (GO:0044843)3.24356779
87positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.23565125
88viral life cycle (GO:0019058)3.22487902
89regulation of mitochondrial translation (GO:0070129)3.22011937
90cellular protein complex disassembly (GO:0043624)3.21353065
91rRNA methylation (GO:0031167)3.20703934
92deoxyribonucleotide biosynthetic process (GO:0009263)3.20595760
93oxidative phosphorylation (GO:0006119)3.19809637
94nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.19419830
95proline biosynthetic process (GO:0006561)3.18685993
96establishment of protein localization to mitochondrial membrane (GO:0090151)3.17577546
97transcription from RNA polymerase I promoter (GO:0006360)3.16836350
98regulation of ubiquitin-protein transferase activity (GO:0051438)3.15673714
99antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.14495413
100mitotic metaphase plate congression (GO:0007080)3.13169447
101pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.13102728
102exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.12902528
103maturation of 5.8S rRNA (GO:0000460)3.12831608
104positive regulation of ligase activity (GO:0051351)3.11683619
105nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.10958946
106spliceosomal complex assembly (GO:0000245)3.06189068
107establishment of protein localization to mitochondrion (GO:0072655)3.03783188
108regulation of ligase activity (GO:0051340)3.03047935
109regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.03004693
110mitotic nuclear envelope disassembly (GO:0007077)3.02607414
1112-deoxyribonucleotide biosynthetic process (GO:0009265)3.01649548
112deoxyribose phosphate biosynthetic process (GO:0046385)3.01649548
113L-serine metabolic process (GO:0006563)3.01530083
114folic acid metabolic process (GO:0046655)3.00274300
115transcription elongation from RNA polymerase I promoter (GO:0006362)3.00190291
116tRNA methylation (GO:0030488)3.00164775
117termination of RNA polymerase I transcription (GO:0006363)3.00000270
118regulation of cellular amine metabolic process (GO:0033238)2.99540275
119establishment of viral latency (GO:0019043)2.99057594
120respiratory electron transport chain (GO:0022904)2.98747937
121pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.97741233
122guanosine-containing compound biosynthetic process (GO:1901070)2.94423582
123protein localization to mitochondrion (GO:0070585)2.94328847
124mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.91484793
125electron transport chain (GO:0022900)2.91310723
126peptidyl-histidine modification (GO:0018202)2.89620228
127pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.87366203
128deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.86263166
129regulation of translational fidelity (GO:0006450)2.85389033
130pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.85021174
131transcription from mitochondrial promoter (GO:0006390)2.84957405
132tRNA aminoacylation for protein translation (GO:0006418)2.82441481
133positive regulation of cell cycle arrest (GO:0071158)2.81038304
134purine nucleotide salvage (GO:0032261)2.80976050
135mitotic nuclear envelope reassembly (GO:0007084)2.79109711
136nuclear envelope reassembly (GO:0031468)2.79109711
137negative regulation of protein ubiquitination (GO:0031397)2.78975267
138protein complex biogenesis (GO:0070271)2.76978801
139amino acid activation (GO:0043038)2.76827018

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.47042905
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.49685921
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.30643312
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.23595801
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.72023959
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.71834262
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.65779588
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.38811259
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.27607869
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.15804622
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.13852101
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.98141130
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.96406189
14E2F4_17652178_ChIP-ChIP_JURKAT_Human2.95383011
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.87158485
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.65879248
17* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.55486276
18XRN2_22483619_ChIP-Seq_HELA_Human2.50499720
19VDR_23849224_ChIP-Seq_CD4+_Human2.49902399
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.45375837
21* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.41667018
22DCP1A_22483619_ChIP-Seq_HELA_Human2.35343889
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33515133
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.33487029
25THAP11_20581084_ChIP-Seq_MESCs_Mouse2.25292286
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.23607030
27FOXM1_23109430_ChIP-Seq_U2OS_Human2.22870390
28CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.22006405
29* FOXP3_21729870_ChIP-Seq_TREG_Human2.17003995
30E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.14890951
31SRF_21415370_ChIP-Seq_HL-1_Mouse2.14183650
32* GABP_19822575_ChIP-Seq_HepG2_Human2.11552030
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.00649088
34* YY1_21170310_ChIP-Seq_MESCs_Mouse1.98095670
35TTF2_22483619_ChIP-Seq_HELA_Human1.96798104
36PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.93666697
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.86523206
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.85141363
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85120511
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.84797678
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.76892584
42ELK1_19687146_ChIP-ChIP_HELA_Human1.75354988
43ZNF263_19887448_ChIP-Seq_K562_Human1.72503191
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.70572795
45* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70458331
46MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.69638832
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.65986091
48AR_21909140_ChIP-Seq_LNCAP_Human1.63876710
49* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60645039
50FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.60243073
51* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.59939976
52NANOG_18555785_ChIP-Seq_MESCs_Mouse1.54564101
53ZFX_18555785_ChIP-Seq_MESCs_Mouse1.53868601
54E2F1_21310950_ChIP-Seq_MCF-7_Human1.49419590
55* CIITA_25753668_ChIP-Seq_RAJI_Human1.46434760
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.44765484
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.42947898
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39976070
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32807566
60MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30586756
61KDM5A_27292631_Chip-Seq_BREAST_Human1.29311155
62CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.26332412
63ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.26034531
64PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24014091
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.21712739
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.18443093
67CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.17974532
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.17911301
69SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.14507974
70ELK1_22589737_ChIP-Seq_MCF10A_Human1.14411480
71MYC_18940864_ChIP-ChIP_HL60_Human1.12753232
72E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.12303634
73* TET1_21451524_ChIP-Seq_MESCs_Mouse1.08218053
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.07703512
75NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.06514866
76RBPJ_22232070_ChIP-Seq_NCS_Mouse1.06040403
77STAT3_1855785_ChIP-Seq_MESCs_Mouse1.05913248
78ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.04056121
79ESR1_15608294_ChIP-ChIP_MCF-7_Human1.02816939
80TFEB_21752829_ChIP-Seq_HELA_Human1.01621579
81KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01542837
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01474996
83TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00824797
84* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.00159338
85CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00086452
86ELF1_20517297_ChIP-Seq_JURKAT_Human0.97819724
87* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.97691479
88* FOXP1_21924763_ChIP-Seq_HESCs_Human0.97564026
89POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.97426546
90SPI1_23547873_ChIP-Seq_NB4_Human0.95361275
91SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.95306220
92DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.95026251
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95009499
94ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.94719335
95* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91518128
96MYC_22102868_ChIP-Seq_BL_Human0.90987404
97SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89419743
98KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.89089179
99CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.88167499
100* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.87164795
101LXR_22292898_ChIP-Seq_THP-1_Human0.86489764
102HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.85807031
103SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.85242582
104TBX5_21415370_ChIP-Seq_HL-1_Mouse0.84881186
105EGR1_19374776_ChIP-ChIP_THP-1_Human0.84803587
106BCL6_27268052_Chip-Seq_Bcells_Human0.83853541
107P68_20966046_ChIP-Seq_HELA_Human0.83492118
108* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81630640
109SOX2_18555785_ChIP-Seq_MESCs_Mouse0.80463737
110HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79754364
111* SOX17_20123909_ChIP-Seq_XEN_Mouse0.78876239
112TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.77900506
113CTCF_18555785_ChIP-Seq_MESCs_Mouse0.75492416
114KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.75261178
115GATA1_22383799_ChIP-Seq_G1ME_Mouse0.75137494
116CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.73890368
117VDR_21846776_ChIP-Seq_THP-1_Human0.73669064
118YY1_22570637_ChIP-Seq_MALME-3M_Human0.71446245

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.67342531
2MP0004957_abnormal_blastocyst_morpholog4.48253111
3MP0003111_abnormal_nucleus_morphology3.90755765
4MP0010094_abnormal_chromosome_stability3.87867232
5MP0008057_abnormal_DNA_replication3.82500546
6MP0003077_abnormal_cell_cycle3.60770119
7MP0008058_abnormal_DNA_repair3.58594579
8MP0003806_abnormal_nucleotide_metabolis3.52043542
9MP0002396_abnormal_hematopoietic_system3.22308289
10MP0008932_abnormal_embryonic_tissue3.10087593
11MP0008007_abnormal_cellular_replicative2.67978101
12MP0005058_abnormal_lysosome_morphology2.62083276
13MP0003186_abnormal_redox_activity2.33062077
14MP0004147_increased_porphyrin_level2.16031507
15MP0003786_premature_aging2.15465822
16MP0001730_embryonic_growth_arrest2.09198615
17MP0009697_abnormal_copulation2.01930001
18MP0009333_abnormal_splenocyte_physiolog2.01387900
19MP0000490_abnormal_crypts_of1.99017457
20MP0004233_abnormal_muscle_weight1.97274938
21MP0009379_abnormal_foot_pigmentation1.95082940
22MP0001529_abnormal_vocalization1.93861459
23MP0006036_abnormal_mitochondrial_physio1.91789716
24MP0003718_maternal_effect1.87114871
25MP0005451_abnormal_body_composition1.85920392
26MP0003656_abnormal_erythrocyte_physiolo1.77719537
27MP0009840_abnormal_foam_cell1.76465550
28MP0000350_abnormal_cell_proliferation1.74820102
29MP0002877_abnormal_melanocyte_morpholog1.73942407
30MP0003123_paternal_imprinting1.73106501
31MP0003191_abnormal_cellular_cholesterol1.66387850
32MP0001764_abnormal_homeostasis1.60014718
33MP0005360_urolithiasis1.54906432
34MP0006054_spinal_hemorrhage1.53897300
35MP0000678_abnormal_parathyroid_gland1.51296548
36MP0008875_abnormal_xenobiotic_pharmacok1.51220282
37MP0005501_abnormal_skin_physiology1.48164310
38MP0006035_abnormal_mitochondrial_morpho1.41617164
39MP0000313_abnormal_cell_death1.36750099
40MP0001881_abnormal_mammary_gland1.35758271
41MP0001697_abnormal_embryo_size1.35756464
42MP0002080_prenatal_lethality1.33148191
43MP0001545_abnormal_hematopoietic_system1.32672787
44MP0005397_hematopoietic_system_phenotyp1.32672787
45MP0002796_impaired_skin_barrier1.31230452
46MP0000358_abnormal_cell_content/1.29539640
47MP0005075_abnormal_melanosome_morpholog1.28127739
48MP0010352_gastrointestinal_tract_polyps1.27914839
49MP0002019_abnormal_tumor_incidence1.25478808
50MP0003763_abnormal_thymus_physiology1.24509622
51MP0005380_embryogenesis_phenotype1.19346728
52MP0001672_abnormal_embryogenesis/_devel1.19346728
53MP0008877_abnormal_DNA_methylation1.17910575
54MP0003315_abnormal_perineum_morphology1.16671935
55MP0002132_abnormal_respiratory_system1.13831446
56MP0002139_abnormal_hepatobiliary_system1.13363233
57MP0003984_embryonic_growth_retardation1.13057210
58MP0005332_abnormal_amino_acid1.12407324
59MP0001661_extended_life_span1.09297754
60MP0004133_heterotaxia1.08198400
61MP0002088_abnormal_embryonic_growth/wei1.06232703
62MP0005330_cardiomyopathy1.06016530
63MP0003567_abnormal_fetal_cardiomyocyte1.05908770
64MP0001853_heart_inflammation1.04780733
65MP0003221_abnormal_cardiomyocyte_apopto1.03488165
66MP0000689_abnormal_spleen_morphology1.03071200
67MP0002938_white_spotting1.02820872
68MP0000465_gastrointestinal_hemorrhage1.01235741
69MP0005266_abnormal_metabolism0.97630936
70MP0002085_abnormal_embryonic_tissue0.97108299
71MP0006292_abnormal_olfactory_placode0.96040841
72MP0002722_abnormal_immune_system0.95765668
73MP0002398_abnormal_bone_marrow0.94144021
74MP0002160_abnormal_reproductive_system0.91140427
75MP0009053_abnormal_anal_canal0.90414666
76MP0002060_abnormal_skin_morphology0.89607307
77MP0005670_abnormal_white_adipose0.89231508
78MP0005220_abnormal_exocrine_pancreas0.87015258
79MP0010030_abnormal_orbit_morphology0.86549701
80MP0005410_abnormal_fertilization0.86128911
81MP0002429_abnormal_blood_cell0.84098033
82MP0000703_abnormal_thymus_morphology0.83921839
83MP0005319_abnormal_enzyme/_coenzyme0.83523298
84MP0002095_abnormal_skin_pigmentation0.83121282
85MP0002751_abnormal_autonomic_nervous0.83048072
86MP0005395_other_phenotype0.81939145
87MP0001145_abnormal_male_reproductive0.81683368
88MP0002210_abnormal_sex_determination0.81054884
89MP0005408_hypopigmentation0.80922424
90MP0001293_anophthalmia0.78529098
91MP0005636_abnormal_mineral_homeostasis0.77301232
92MP0008873_increased_physiological_sensi0.76926691
93MP0002086_abnormal_extraembryonic_tissu0.76203081
94MP0001666_abnormal_nutrient_absorption0.76125523
95MP0001216_abnormal_epidermal_layer0.73677720
96MP0004185_abnormal_adipocyte_glucose0.73539601
97MP0001243_abnormal_dermal_layer0.72329737
98MP0005376_homeostasis/metabolism_phenot0.72180174
99MP0009278_abnormal_bone_marrow0.71652479
100MP0005384_cellular_phenotype0.71649004
101MP0005365_abnormal_bile_salt0.71518527
102MP0000609_abnormal_liver_physiology0.70574061
103MP0000749_muscle_degeneration0.70365097
104MP0000858_altered_metastatic_potential0.70161946
105MP0008260_abnormal_autophagy0.69849843
106MP0002084_abnormal_developmental_patter0.69688991
107MP0005389_reproductive_system_phenotype0.69312440
108MP0000627_abnormal_mammary_gland0.68425397
109MP0003890_abnormal_embryonic-extraembry0.68025802
110MP0004808_abnormal_hematopoietic_stem0.67781757
111MP0001873_stomach_inflammation0.67273237
112MP0000015_abnormal_ear_pigmentation0.65105832
113MP0000372_irregular_coat_pigmentation0.64381211
114MP0000716_abnormal_immune_system0.64053876
115MP0000653_abnormal_sex_gland0.62846091
116MP0009672_abnormal_birth_weight0.62108808
117MP0001119_abnormal_female_reproductive0.61896659
118MP0009931_abnormal_skin_appearance0.61677889
119MP0004197_abnormal_fetal_growth/weight/0.61137844
120MP0003941_abnormal_skin_development0.61033826
121MP0002148_abnormal_hypersensitivity_rea0.60041006
122MP0004019_abnormal_vitamin_homeostasis0.58859009
123MP0001727_abnormal_embryo_implantation0.58688874
124MP0003172_abnormal_lysosome_physiology0.58106668
125MP0001186_pigmentation_phenotype0.57414901
126MP0003646_muscle_fatigue0.57395521
127MP0000049_abnormal_middle_ear0.57158365
128MP0005174_abnormal_tail_pigmentation0.56801461
129MP0010771_integument_phenotype0.56747860
130MP0004264_abnormal_extraembryonic_tissu0.56648722
131MP0001542_abnormal_bone_strength0.56042361
132MP0005464_abnormal_platelet_physiology0.55410647
133MP0002970_abnormal_white_adipose0.55286957
134MP0001905_abnormal_dopamine_level0.55238807
135MP0004142_abnormal_muscle_tone0.53839718
136MP0000598_abnormal_liver_morphology0.53763039
137MP0002111_abnormal_tail_morphology0.52788662
138MP0005621_abnormal_cell_physiology0.52308878
139MP0003724_increased_susceptibility_to0.52147798
140MP0001929_abnormal_gametogenesis0.51772228
141MP0010307_abnormal_tumor_latency0.49898234
142MP0005083_abnormal_biliary_tract0.49105594

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.79719191
2Abnormal number of erythroid precursors (HP:0012131)4.75648124
3Abnormality of cells of the erythroid lineage (HP:0012130)4.69175526
4Carpal bone hypoplasia (HP:0001498)4.07266954
5Hepatocellular necrosis (HP:0001404)3.95799703
6Mitochondrial inheritance (HP:0001427)3.88667904
7Acute necrotizing encephalopathy (HP:0006965)3.86275802
8Cerebral hypomyelination (HP:0006808)3.81318764
9Hepatic necrosis (HP:0002605)3.79642475
10Aplastic anemia (HP:0001915)3.79178697
11Reticulocytopenia (HP:0001896)3.76609219
12Breast hypoplasia (HP:0003187)3.73901446
13Increased serum pyruvate (HP:0003542)3.67305091
14Abnormality of glycolysis (HP:0004366)3.67305091
15Degeneration of anterior horn cells (HP:0002398)3.67293171
16Abnormality of the anterior horn cell (HP:0006802)3.67293171
17Increased CSF lactate (HP:0002490)3.67184228
18Abnormal mitochondria in muscle tissue (HP:0008316)3.65909938
19Cholecystitis (HP:0001082)3.60992955
20Abnormal gallbladder physiology (HP:0012438)3.60992955
21Increased serum lactate (HP:0002151)3.59372019
22Oral leukoplakia (HP:0002745)3.53864840
23Decreased activity of mitochondrial respiratory chain (HP:0008972)3.49030234
24Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.49030234
25Acute encephalopathy (HP:0006846)3.31098845
26Microretrognathia (HP:0000308)3.17926953
27Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.10627482
28Macrocytic anemia (HP:0001972)3.10103838
29Rough bone trabeculation (HP:0100670)2.97748660
30Increased hepatocellular lipid droplets (HP:0006565)2.89629375
31Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.85129732
323-Methylglutaconic aciduria (HP:0003535)2.83424302
33Abnormality of the heme biosynthetic pathway (HP:0010472)2.81708909
34Lactic acidosis (HP:0003128)2.80935220
35Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.78396789
36Progressive macrocephaly (HP:0004481)2.77722731
37Exercise intolerance (HP:0003546)2.66458018
38Respiratory failure (HP:0002878)2.62775244
39Pallor (HP:0000980)2.62481814
40Progressive muscle weakness (HP:0003323)2.62417655
41Patellar aplasia (HP:0006443)2.60088259
42Lipid accumulation in hepatocytes (HP:0006561)2.58467962
43Pancytopenia (HP:0001876)2.58079094
44CNS demyelination (HP:0007305)2.56696823
45Exertional dyspnea (HP:0002875)2.55118313
46Spastic paraparesis (HP:0002313)2.52836363
47Abnormality of aromatic amino acid family metabolism (HP:0004338)2.52786926
48Testicular atrophy (HP:0000029)2.51560371
49* Type I transferrin isoform profile (HP:0003642)2.49840146
50Lethargy (HP:0001254)2.42719909
51CNS hypomyelination (HP:0003429)2.40307028
52Aplasia/Hypoplasia of the patella (HP:0006498)2.39111538
53Irregular epiphyses (HP:0010582)2.38860258
54Multiple enchondromatosis (HP:0005701)2.37120264
55Hyperammonemia (HP:0001987)2.36981813
56Selective tooth agenesis (HP:0001592)2.35189702
57Hypokinesia (HP:0002375)2.34768817
58Renal Fanconi syndrome (HP:0001994)2.33731361
59Premature graying of hair (HP:0002216)2.32713613
60Colon cancer (HP:0003003)2.31029854
61Cerebral edema (HP:0002181)2.30413071
62Seborrheic dermatitis (HP:0001051)2.29269302
63Reduced antithrombin III activity (HP:0001976)2.26706161
64Hypoplasia of the capital femoral epiphysis (HP:0003090)2.25751100
65Increased intramyocellular lipid droplets (HP:0012240)2.23971970
66Emotional lability (HP:0000712)2.23694397
67Nausea (HP:0002018)2.23327035
68Abnormality of alanine metabolism (HP:0010916)2.23038426
69Hyperalaninemia (HP:0003348)2.23038426
70Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.23038426
71Hypoplastic pelvis (HP:0008839)2.21663355
72Dicarboxylic aciduria (HP:0003215)2.19507694
73Abnormality of dicarboxylic acid metabolism (HP:0010995)2.19507694
74Vertebral compression fractures (HP:0002953)2.16104038
75Abnormality of methionine metabolism (HP:0010901)2.15719933
76Sparse eyelashes (HP:0000653)2.13746020
77Respiratory difficulties (HP:0002880)2.11235570
78Ragged-red muscle fibers (HP:0003200)2.10863922
79Microvesicular hepatic steatosis (HP:0001414)2.10788404
80Poor head control (HP:0002421)2.10062604
81Chromosomal breakage induced by crosslinking agents (HP:0003221)2.06938355
82Aplasia/Hypoplasia of the sacrum (HP:0008517)2.06078607
8311 pairs of ribs (HP:0000878)2.05685027
84Megaloblastic anemia (HP:0001889)2.04348278
85Achilles tendon contracture (HP:0001771)2.03817370
86Abnormal trabecular bone morphology (HP:0100671)2.02223792
87Bone marrow hypocellularity (HP:0005528)2.02018136
88Horseshoe kidney (HP:0000085)2.00601957
89Tongue fasciculations (HP:0001308)1.99714664
90Thrombocytosis (HP:0001894)1.99119639
91Generalized aminoaciduria (HP:0002909)1.99017132
92Progressive microcephaly (HP:0000253)1.98780110
93Chromsome breakage (HP:0040012)1.96732472
94Opisthotonus (HP:0002179)1.96696900
95* Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.96100307
96* Abnormal protein N-linked glycosylation (HP:0012347)1.96100307
97* Abnormal protein glycosylation (HP:0012346)1.96100307
98* Abnormal glycosylation (HP:0012345)1.96100307
99Cellular immunodeficiency (HP:0005374)1.95426148
100Postnatal microcephaly (HP:0005484)1.95309395
101Absent thumb (HP:0009777)1.94999793
102Atrophy/Degeneration involving motor neurons (HP:0007373)1.94114818
103Abnormality of the umbilical cord (HP:0010881)1.93746546
104Abnormality of the Achilles tendon (HP:0005109)1.91985486
105Secondary amenorrhea (HP:0000869)1.91222024
106Premature ovarian failure (HP:0008209)1.90936404
107Abnormality of pyrimidine metabolism (HP:0004353)1.90776338
108Trismus (HP:0000211)1.90397977
109Abnormality of the pons (HP:0007361)1.90153706
110Type 2 muscle fiber atrophy (HP:0003554)1.88105348
111Absent radius (HP:0003974)1.88014173
112Abnormality of the preputium (HP:0100587)1.86778336
113Reduced subcutaneous adipose tissue (HP:0003758)1.86042040
114Nonimmune hydrops fetalis (HP:0001790)1.85731363
115Upper limb muscle weakness (HP:0003484)1.85292802
116Increased muscle lipid content (HP:0009058)1.85231051
117Death in infancy (HP:0001522)1.84753470
118Hypoplasia of the pons (HP:0012110)1.84712077
119Abnormality of serum amino acid levels (HP:0003112)1.84486216
120Leukodystrophy (HP:0002415)1.84388436
121Unsteady gait (HP:0002317)1.84039080
122Abnormal number of incisors (HP:0011064)1.83287953
123Hypertensive crisis (HP:0100735)1.82897345
124Aplasia/Hypoplasia involving the musculature (HP:0001460)1.82448971
125Muscle fiber atrophy (HP:0100295)1.82173731
126Absent epiphyses (HP:0010577)1.81263881
127Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.81263881
128Cholelithiasis (HP:0001081)1.80395128
129Cleft eyelid (HP:0000625)1.75074567
130Abnormality of reticulocytes (HP:0004312)1.73742667
131Hypergonadotropic hypogonadism (HP:0000815)1.73103907
132Abnormal pupillary function (HP:0007686)1.72368615
133Methylmalonic aciduria (HP:0012120)1.70268755
134Patchy hypopigmentation of hair (HP:0011365)1.67681876

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.74076945
2VRK24.45486508
3EIF2AK13.83596280
4WEE13.82080080
5STK163.59475286
6EIF2AK33.03247633
7NME23.03222401
8SRPK12.89283263
9TSSK62.77195405
10CDC72.75376237
11VRK12.74151562
12PIM22.40628887
13TESK22.20443619
14PDK22.01399489
15NEK11.87088583
16PLK41.85461174
17SMG11.71749439
18BCKDK1.71678264
19MKNK11.68101556
20TAF11.63178554
21SCYL21.63158274
22BRSK21.61069801
23MST1R1.59727524
24CDK71.53495394
25TLK11.44020844
26PLK11.43892516
27CDK81.43432300
28ATR1.33909344
29KDR1.32770123
30AURKA1.29533897
31RPS6KA41.29445230
32CCNB11.28844272
33TTK1.26736299
34NME11.25806755
35BRSK11.22411945
36MAP3K111.21142605
37PASK1.20521177
38PLK31.19943348
39AURKB1.19603645
40NEK21.16132532
41DYRK31.15224641
42MAP3K121.14358843
43RPS6KB21.13964818
44MKNK21.11701961
45MAP4K11.04602436
46ACVR1B1.03102034
47ZAK1.02578061
48EIF2AK20.99524466
49STK100.97532070
50BRAF0.97062945
51MAP3K80.91243989
52IRAK40.90006002
53NUAK10.88477808
54IRAK30.88387374
55PTK20.86752533
56CSNK2A10.85785217
57PAK40.81727281
58TESK10.81680458
59KIT0.77841765
60CHEK20.76621352
61TRIM280.76507849
62ABL20.76404769
63ILK0.75608094
64CSNK2A20.75066370
65PIM10.73450859
66PBK0.72795222
67PAK10.71616817
68LIMK10.69809497
69MET0.69227800
70MAP2K30.67294626
71ICK0.66814950
72MAPKAPK50.66805702
73LRRK20.66474771
74MAPKAPK30.64883896
75CSNK1G30.64531699
76TEC0.64211354
77MST40.64030754
78CHEK10.63899803
79MAP4K20.62756993
80SIK30.61708108
81ERN10.61619744
82EPHA20.61340740
83CLK10.61222438
84CDK40.59035692
85DYRK20.57833776
86CDK190.57702450
87RPS6KA50.57236047
88BTK0.57095721
89ERBB40.56800595
90MYLK0.54496242
91STK40.54275022
92MAP3K30.53427391
93CDK20.47553309
94ATM0.47344016
95RPS6KA60.45285137
96AKT30.43232002
97FLT30.42356138
98MARK30.42194559
99OBSCN0.41556297
100LMTK20.40762290
101ZAP700.40655338
102TAOK20.39935752
103PRKCI0.39799198
104TXK0.39009373
105CDK90.38742283
106MAPK110.37659553
107TBK10.37125324
108MAPKAPK20.36411904
109AKT20.35547839
110BLK0.34892690
111CDK10.34311568
112RPS6KC10.34132293
113RPS6KL10.34132293
114LYN0.31783176
115DAPK30.31574694
116PNCK0.31066847
117ARAF0.30592495
118CSNK1A1L0.30162876
119IRAK10.28686907
120BRD40.28377023
121MAPK150.28111234
122DAPK10.27756913
123MUSK0.27598825
124IKBKB0.27180278
125YES10.26743035
126CSNK1G10.26617902
127MAP3K60.25417964

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.49391671
2Proteasome_Homo sapiens_hsa030504.36428152
3Ribosome_Homo sapiens_hsa030104.06212364
4RNA polymerase_Homo sapiens_hsa030203.74311903
5Mismatch repair_Homo sapiens_hsa034303.54655045
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.28187636
7Base excision repair_Homo sapiens_hsa034102.85614403
8Pyrimidine metabolism_Homo sapiens_hsa002402.79755012
9Spliceosome_Homo sapiens_hsa030402.72529741
10Nucleotide excision repair_Homo sapiens_hsa034202.60464403
11Homologous recombination_Homo sapiens_hsa034402.52094879
12RNA transport_Homo sapiens_hsa030132.42527263
13Protein export_Homo sapiens_hsa030602.39501209
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.27758156
15One carbon pool by folate_Homo sapiens_hsa006702.17868721
16Oxidative phosphorylation_Homo sapiens_hsa001902.06881580
17Parkinsons disease_Homo sapiens_hsa050121.93287757
18Cell cycle_Homo sapiens_hsa041101.77126106
19Non-homologous end-joining_Homo sapiens_hsa034501.73461174
20Huntingtons disease_Homo sapiens_hsa050161.55819626
21Purine metabolism_Homo sapiens_hsa002301.53260574
22Folate biosynthesis_Homo sapiens_hsa007901.49644356
23Basal transcription factors_Homo sapiens_hsa030221.45662065
24RNA degradation_Homo sapiens_hsa030181.45053497
25Fanconi anemia pathway_Homo sapiens_hsa034601.44646047
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.42018540
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.33167384
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.30622822
29Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.30173979
30Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.29929831
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.19441633
32Drug metabolism - other enzymes_Homo sapiens_hsa009831.11604467
33Biosynthesis of amino acids_Homo sapiens_hsa012301.11311096
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.10457777
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.09461628
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.06581539
37Glutathione metabolism_Homo sapiens_hsa004801.06377076
38Alzheimers disease_Homo sapiens_hsa050101.05432667
39Pentose phosphate pathway_Homo sapiens_hsa000301.05016141
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.01892896
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.97734200
42p53 signaling pathway_Homo sapiens_hsa041150.95045199
43Cyanoamino acid metabolism_Homo sapiens_hsa004600.94014937
44Epstein-Barr virus infection_Homo sapiens_hsa051690.90392600
45* N-Glycan biosynthesis_Homo sapiens_hsa005100.90111524
46Carbon metabolism_Homo sapiens_hsa012000.89202414
47Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.81669901
48Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80696429
49mRNA surveillance pathway_Homo sapiens_hsa030150.78943717
50Selenocompound metabolism_Homo sapiens_hsa004500.75511945
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.75228511
52* Metabolic pathways_Homo sapiens_hsa011000.69659016
53Pentose and glucuronate interconversions_Homo sapiens_hsa000400.68544962
54Sulfur relay system_Homo sapiens_hsa041220.66676827
55Fatty acid metabolism_Homo sapiens_hsa012120.64018111
56Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60560772
57Legionellosis_Homo sapiens_hsa051340.60351023
58Fructose and mannose metabolism_Homo sapiens_hsa000510.58485679
59Arginine and proline metabolism_Homo sapiens_hsa003300.55673135
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55366392
61Antigen processing and presentation_Homo sapiens_hsa046120.52345986
62Arachidonic acid metabolism_Homo sapiens_hsa005900.51957105
63Other glycan degradation_Homo sapiens_hsa005110.51707086
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50969761
65Arginine biosynthesis_Homo sapiens_hsa002200.50727221
66Steroid biosynthesis_Homo sapiens_hsa001000.49722124
67Pyruvate metabolism_Homo sapiens_hsa006200.47983348
68Galactose metabolism_Homo sapiens_hsa000520.47900926
69Vitamin B6 metabolism_Homo sapiens_hsa007500.47816891
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.47759199
71Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.46897898
72Fatty acid elongation_Homo sapiens_hsa000620.46363581
73Herpes simplex infection_Homo sapiens_hsa051680.44961832
74Fatty acid degradation_Homo sapiens_hsa000710.40598462
75Systemic lupus erythematosus_Homo sapiens_hsa053220.37045538
76Sulfur metabolism_Homo sapiens_hsa009200.36844649
77Cardiac muscle contraction_Homo sapiens_hsa042600.33909411
78Primary bile acid biosynthesis_Homo sapiens_hsa001200.33094467
79Viral carcinogenesis_Homo sapiens_hsa052030.31502215
80Chemical carcinogenesis_Homo sapiens_hsa052040.27662492
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.26589651
82Renin-angiotensin system_Homo sapiens_hsa046140.24726802
83Thyroid cancer_Homo sapiens_hsa052160.24331425
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23288313
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.23190196
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.23109256
87Lysosome_Homo sapiens_hsa041420.22048825
88Regulation of autophagy_Homo sapiens_hsa041400.20215019
89Linoleic acid metabolism_Homo sapiens_hsa005910.20101357
90Oocyte meiosis_Homo sapiens_hsa041140.19389272
91Retinol metabolism_Homo sapiens_hsa008300.18819548
92Hematopoietic cell lineage_Homo sapiens_hsa046400.17029266
93Peroxisome_Homo sapiens_hsa041460.16875048
94HTLV-I infection_Homo sapiens_hsa051660.16578123
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.16542651
96Propanoate metabolism_Homo sapiens_hsa006400.15855937
97beta-Alanine metabolism_Homo sapiens_hsa004100.15044413
98Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.14510995
99Bladder cancer_Homo sapiens_hsa052190.14401462
100Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.14380052
101Butanoate metabolism_Homo sapiens_hsa006500.14292605
102Starch and sucrose metabolism_Homo sapiens_hsa005000.14274309
103Shigellosis_Homo sapiens_hsa051310.14264443
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.13727966
105Vibrio cholerae infection_Homo sapiens_hsa051100.12729093
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.12466980
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.12077534
108Asthma_Homo sapiens_hsa053100.11687822
109Primary immunodeficiency_Homo sapiens_hsa053400.10469557
110Vitamin digestion and absorption_Homo sapiens_hsa049770.08331321
111Apoptosis_Homo sapiens_hsa042100.07882983
112Phenylalanine metabolism_Homo sapiens_hsa003600.07518189
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.06433777
114Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.06294062
115Fat digestion and absorption_Homo sapiens_hsa049750.05790197
116Glycosaminoglycan degradation_Homo sapiens_hsa005310.04915162
117Tyrosine metabolism_Homo sapiens_hsa003500.04441552

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