AJUBA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* regulation of gene silencing by miRNA (GO:0060964)5.13026300
2* regulation of gene silencing by RNA (GO:0060966)5.13026300
3* regulation of posttranscriptional gene silencing (GO:0060147)5.13026300
4desmosome organization (GO:0002934)5.02040761
5paraxial mesoderm development (GO:0048339)4.94541122
6nuclear pore organization (GO:0006999)4.34346598
7nuclear pore complex assembly (GO:0051292)4.16473282
8cell adhesion mediated by integrin (GO:0033627)4.13686005
9DNA unwinding involved in DNA replication (GO:0006268)4.00795798
10negative regulation of fibrinolysis (GO:0051918)3.98801783
11* cell-substrate junction assembly (GO:0007044)3.95734377
12establishment of apical/basal cell polarity (GO:0035089)3.87237451
13pre-miRNA processing (GO:0031054)3.87061502
14protein localization to kinetochore (GO:0034501)3.73446931
15DNA replication-dependent nucleosome organization (GO:0034723)3.71004408
16DNA replication-dependent nucleosome assembly (GO:0006335)3.71004408
17gap junction assembly (GO:0016264)3.70642146
18positive regulation of SMAD protein import into nucleus (GO:0060391)3.60709813
19bundle of His cell to Purkinje myocyte communication (GO:0086069)3.57231700
20mitotic nuclear envelope disassembly (GO:0007077)3.53969203
21heterochromatin organization (GO:0070828)3.52763233
22negative regulation of chondrocyte differentiation (GO:0032331)3.51805334
23folic acid-containing compound biosynthetic process (GO:0009396)3.48764957
24polarized epithelial cell differentiation (GO:0030859)3.47010961
25skin morphogenesis (GO:0043589)3.44977340
26endodermal cell differentiation (GO:0035987)3.41614811
27IMP biosynthetic process (GO:0006188)3.40775529
28hemidesmosome assembly (GO:0031581)3.39743598
29mitotic metaphase plate congression (GO:0007080)3.36012994
30regulation of SMAD protein import into nucleus (GO:0060390)3.35967413
31membrane disassembly (GO:0030397)3.30708553
32nuclear envelope disassembly (GO:0051081)3.30708553
33DNA replication initiation (GO:0006270)3.30047095
34notochord development (GO:0030903)3.29712433
35negative regulation of keratinocyte proliferation (GO:0010839)3.29523899
36formation of translation preinitiation complex (GO:0001731)3.28463427
37Golgi transport vesicle coating (GO:0048200)3.28295166
38COPI coating of Golgi vesicle (GO:0048205)3.28295166
39regulation of fibrinolysis (GO:0051917)3.27787237
40protein carboxylation (GO:0018214)3.23947313
41peptidyl-glutamic acid carboxylation (GO:0017187)3.23947313
42mesodermal cell differentiation (GO:0048333)3.22956428
43regulation of plasminogen activation (GO:0010755)3.22068809
44lung-associated mesenchyme development (GO:0060484)3.20671513
45establishment of monopolar cell polarity (GO:0061162)3.20411869
46establishment or maintenance of monopolar cell polarity (GO:0061339)3.20411869
47regulation of transforming growth factor beta2 production (GO:0032909)3.17373958
48basement membrane organization (GO:0071711)3.15126116
49nucleobase biosynthetic process (GO:0046112)3.13228934
50regulation of translational fidelity (GO:0006450)3.13202811
51hippo signaling (GO:0035329)3.11457012
52maturation of SSU-rRNA (GO:0030490)3.10224475
53embryonic camera-type eye development (GO:0031076)3.08481688
54pore complex assembly (GO:0046931)3.08264034
55intestinal cholesterol absorption (GO:0030299)3.07841848
56planar cell polarity pathway involved in neural tube closure (GO:0090179)3.07784065
57ribosome assembly (GO:0042255)3.04376212
58regulation of spindle organization (GO:0090224)3.04316157
59* regulation of hippo signaling (GO:0035330)3.03585925
60regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.03529616
61anterior/posterior axis specification, embryo (GO:0008595)3.02825337
62Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.02005940
63regulation of mitotic spindle organization (GO:0060236)3.01169967
64peptidyl-arginine omega-N-methylation (GO:0035247)2.97710981
65mitotic sister chromatid segregation (GO:0000070)2.97403850
66apoptotic process involved in morphogenesis (GO:0060561)2.92882658
67dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.91760849
68maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.90895062
69protein localization to chromosome, centromeric region (GO:0071459)2.90750447
70nodal signaling pathway (GO:0038092)2.90557312
71regulation of cardioblast differentiation (GO:0051890)2.89564676
72regulation of establishment of planar polarity (GO:0090175)2.89031018
73regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.88450092
74DNA duplex unwinding (GO:0032508)2.87842042
75regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.87413130
76IMP metabolic process (GO:0046040)2.87157365
77convergent extension (GO:0060026)2.86925226
78atrioventricular valve morphogenesis (GO:0003181)2.86759146
79DNA geometric change (GO:0032392)2.86243573
80regulation of helicase activity (GO:0051095)2.84681246
81endothelial cell morphogenesis (GO:0001886)2.84665296
82* cell-substrate adherens junction assembly (GO:0007045)2.82304193
83* focal adhesion assembly (GO:0048041)2.82304193
84metaphase plate congression (GO:0051310)2.81399418
85regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.79134077
86negative regulation of cell fate specification (GO:0009996)2.78169792
87sister chromatid segregation (GO:0000819)2.77992456
88DNA strand elongation involved in DNA replication (GO:0006271)2.77064662
89* regulation of gene silencing (GO:0060968)2.75286070
90mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.74568280
91establishment of tissue polarity (GO:0007164)2.73937886
92establishment of planar polarity (GO:0001736)2.73937886
93* adherens junction assembly (GO:0034333)2.73445570
94histone arginine methylation (GO:0034969)2.73142415
95histone H2A monoubiquitination (GO:0035518)2.72855488
96cochlea morphogenesis (GO:0090103)2.72305204
97chromatin assembly (GO:0031497)2.70896210
98regulation of telomere maintenance via telomerase (GO:0032210)2.68995773
99protein retention in ER lumen (GO:0006621)2.68675277
100epithelial cell-cell adhesion (GO:0090136)2.67149788
101regulation of histone H3-K9 methylation (GO:0051570)2.67126709
102ribosome biogenesis (GO:0042254)2.65206399
103negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.64263178
104nuclear envelope organization (GO:0006998)2.63607180
105purine nucleobase biosynthetic process (GO:0009113)2.63330178
106branching involved in salivary gland morphogenesis (GO:0060445)2.61871118
107regulation of translational termination (GO:0006449)2.61510041
108DNA strand elongation (GO:0022616)2.60415078
109endocardial cushion development (GO:0003197)2.60121901
110positive regulation of chromosome segregation (GO:0051984)2.59482371
111G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.59114309
112regulation of sister chromatid cohesion (GO:0007063)2.58824493
113negative regulation of fatty acid transport (GO:2000192)2.57549909
114regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.56760520
115regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.56183560
116trophectodermal cell differentiation (GO:0001829)2.55466854
117non-canonical Wnt signaling pathway (GO:0035567)2.55279984
118fibrinolysis (GO:0042730)2.55015266
119mitotic chromosome condensation (GO:0007076)2.52881352
120regulation of stem cell maintenance (GO:2000036)2.51216805
121somatic hypermutation of immunoglobulin genes (GO:0016446)2.50711740
122somatic diversification of immune receptors via somatic mutation (GO:0002566)2.50711740
123peptidyl-arginine methylation (GO:0018216)2.50418927
124peptidyl-arginine N-methylation (GO:0035246)2.50418927
125regulation of centrosome cycle (GO:0046605)2.50324530
126keratinocyte proliferation (GO:0043616)2.50200285
127proline biosynthetic process (GO:0006561)2.49767915
128DNA replication checkpoint (GO:0000076)2.49040882
129cell migration involved in sprouting angiogenesis (GO:0002042)2.48497779
130embryonic foregut morphogenesis (GO:0048617)2.48452212
131spliceosomal tri-snRNP complex assembly (GO:0000244)2.46819444
132negative regulation of chromosome segregation (GO:0051985)2.46286191
133negative regulation of histone methylation (GO:0031061)2.46142773
134very-low-density lipoprotein particle assembly (GO:0034379)2.44550539
135positive regulation of osteoblast proliferation (GO:0033690)2.44309004
136negative regulation of cartilage development (GO:0061037)2.43479151
137regulation of chromosome segregation (GO:0051983)2.43431896
138ribosomal large subunit biogenesis (GO:0042273)2.41632519
139histone H4-K12 acetylation (GO:0043983)2.40795661
140negative regulation of stem cell proliferation (GO:2000647)2.40299005
141establishment of chromosome localization (GO:0051303)2.40084204
142cell surface receptor signaling pathway involved in heart development (GO:0061311)2.39863307
143COPII vesicle coating (GO:0048208)2.38427895
144ribonucleoprotein complex biogenesis (GO:0022613)2.38246553
145chondrocyte proliferation (GO:0035988)2.38135922
146mesenchymal to epithelial transition (GO:0060231)2.37633218
147negative regulation of mRNA processing (GO:0050686)2.37456055
148positive regulation of endothelial cell apoptotic process (GO:2000353)2.37420316
149collagen fibril organization (GO:0030199)2.37029715
150regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.36964595
151negative regulation of mitotic sister chromatid segregation (GO:0033048)2.35457045
152negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.35457045
153negative regulation of sister chromatid segregation (GO:0033046)2.35457045
154negative regulation of mitotic sister chromatid separation (GO:2000816)2.35457045
155retina vasculature morphogenesis in camera-type eye (GO:0061299)2.34200312
156negative regulation of lipase activity (GO:0060192)2.30133675
157activation of Rac GTPase activity (GO:0032863)2.26640369
158ventricular cardiac muscle cell development (GO:0055015)2.25600586
159proline metabolic process (GO:0006560)2.24216076
160* cell junction assembly (GO:0034329)2.23467030
161L-serine metabolic process (GO:0006563)2.22629916
162regulation of keratinocyte proliferation (GO:0010837)2.22513889
163lateral sprouting from an epithelium (GO:0060601)2.21901886
164heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.21841119
165axon extension involved in axon guidance (GO:0048846)2.21169035
166neuron projection extension involved in neuron projection guidance (GO:1902284)2.21169035
167positive regulation of catenin import into nucleus (GO:0035413)2.20911790
168lung epithelium development (GO:0060428)2.20471381
169regulation of hair follicle development (GO:0051797)2.20323380
170regulation of water loss via skin (GO:0033561)2.18241689
171muscle cell migration (GO:0014812)2.17690632
172branching involved in mammary gland duct morphogenesis (GO:0060444)2.16675806
1734-hydroxyproline metabolic process (GO:0019471)2.15600250
174regulation of cholesterol homeostasis (GO:2000188)2.12065050
175* cell junction organization (GO:0034330)2.11537907
176regulation of cholesterol biosynthetic process (GO:0045540)2.11201520
177* adherens junction organization (GO:0034332)2.10806052
178glomerular visceral epithelial cell development (GO:0072015)2.10321639
179protein localization to endosome (GO:0036010)2.10099013
180morphogenesis of an epithelial sheet (GO:0002011)2.09877008
181embryonic skeletal joint morphogenesis (GO:0060272)2.09312472

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.02728149
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.87810165
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.23064125
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.68386177
5MYC_19079543_ChIP-ChIP_MESCs_Mouse2.97024737
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.81972554
7KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.81202414
8KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.81202414
9KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.81202414
10POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.73237296
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.72641859
12SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.63668597
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.59852665
14TRIM28_21343339_ChIP-Seq_HEK293_Human2.56267097
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.48405545
16NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.48252199
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.38070475
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.27136481
19TCF3_18692474_ChIP-Seq_MEFs_Mouse2.25395552
20AR_21909140_ChIP-Seq_LNCAP_Human2.21938837
21ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.20453879
22PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.13748782
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.12459691
24NANOG_18555785_ChIP-Seq_MESCs_Mouse2.03621567
25ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.00764487
26SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.00319341
27MYC_18358816_ChIP-ChIP_MESCs_Mouse1.99702130
28KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.99068965
29MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92436263
30NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.88127182
31TCF3_18692474_ChIP-Seq_MESCs_Mouse1.86981433
32XRN2_22483619_ChIP-Seq_HELA_Human1.83891412
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.83328194
34STAT3_1855785_ChIP-Seq_MESCs_Mouse1.80925535
35SOX2_18555785_ChIP-Seq_MESCs_Mouse1.79368466
36SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.78666518
37TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.78613521
38SALL1_21062744_ChIP-ChIP_HESCs_Human1.78329605
39KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.76313446
40POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.72864074
41SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.69472657
42NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.68228045
43SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.67079213
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66729245
45TP63_19390658_ChIP-ChIP_HaCaT_Human1.61710588
46E2F1_21310950_ChIP-Seq_MCF-7_Human1.59985147
47ESR2_21235772_ChIP-Seq_MCF-7_Human1.57319742
48HIF1A_21447827_ChIP-Seq_MCF-7_Human1.56090703
49E2F1_18555785_ChIP-Seq_MESCs_Mouse1.55340515
50SOX9_24532713_ChIP-Seq_HFSC_Mouse1.55314794
51CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.54234964
52KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.53320770
53WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.53066183
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.53012932
55UBF1/2_26484160_Chip-Seq_HMECs_Human1.52090092
56PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.51765684
57KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.50035824
58TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.49856518
59ESR1_21235772_ChIP-Seq_MCF-7_Human1.40851814
60TP53_22127205_ChIP-Seq_IMR90_Human1.40355577
61KLF4_18555785_ChIP-Seq_MESCs_Mouse1.39330147
62ESR1_15608294_ChIP-ChIP_MCF-7_Human1.38911309
63P300_27058665_Chip-Seq_ZR-75-30cells_Human1.38726649
64ETS1_20019798_ChIP-Seq_JURKAT_Human1.38226366
65RXR_22158963_ChIP-Seq_LIVER_Mouse1.38188528
66MYC_22102868_ChIP-Seq_BL_Human1.36588146
67PPAR_26484153_Chip-Seq_NCI-H1993_Human1.36193642
68SOX2_18692474_ChIP-Seq_MEFs_Mouse1.36155889
69RACK7_27058665_Chip-Seq_MCF-7_Human1.35851977
70NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.35370290
71TTF2_22483619_ChIP-Seq_HELA_Human1.32006430
72ZNF263_19887448_ChIP-Seq_K562_Human1.30705678
73UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.29288453
74SALL4_18804426_ChIP-ChIP_XEN_Mouse1.27572036
75PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.27460567
76CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.26659985
77POU5F1_16518401_ChIP-PET_MESCs_Mouse1.26588882
78STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26391011
79NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.26356033
80ZFX_18555785_ChIP-Seq_MESCs_Mouse1.26339672
81EST1_17652178_ChIP-ChIP_JURKAT_Human1.26259128
82P63_26484246_Chip-Seq_KERATINOCYTES_Human1.26057639
83NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.24858705
84CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.24664324
85CREB1_15753290_ChIP-ChIP_HEK293T_Human1.23827953
86RARG_19884340_ChIP-ChIP_MEFs_Mouse1.23637908
87SOX2_18692474_ChIP-Seq_MESCs_Mouse1.23394051
88BRD4_25478319_ChIP-Seq_HGPS_Human1.23242578
89EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.23195839
90NANOG_21062744_ChIP-ChIP_HESCs_Human1.23178927
91ATF3_27146783_Chip-Seq_COLON_Human1.22592662
92OCT4_18692474_ChIP-Seq_MEFs_Mouse1.22181448
93SOX17_20123909_ChIP-Seq_XEN_Mouse1.21994230
94NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.20503484
95NANOG_18692474_ChIP-Seq_MEFs_Mouse1.19801551
96FOXA2_19822575_ChIP-Seq_HepG2_Human1.19554458
97PPARA_22158963_ChIP-Seq_LIVER_Mouse1.18255026
98ZFP281_18757296_ChIP-ChIP_E14_Mouse1.16618224
99WT1_19549856_ChIP-ChIP_CCG9911_Human1.16539290
100TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.15695984
101TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13932528
102CJUN_26792858_Chip-Seq_BT549_Human1.13559818
103DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13389798
104HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.13328462
105ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.13021905
106NANOG_16153702_ChIP-ChIP_HESCs_Human1.12228445
107RBPJ_22232070_ChIP-Seq_NCS_Mouse1.11744971
108CLOCK_20551151_ChIP-Seq_293T_Human1.11360985
109HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.11336705
110TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.11019225
111NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.10440139
112SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.10206813
113DCP1A_22483619_ChIP-Seq_HELA_Human1.09959043
114HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.09903504
115TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09512033
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09457629
117SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.07778991
118TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07475759
119ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.07021319
120GATA6_25053715_ChIP-Seq_YYC3_Human1.06192909
121EP300_21415370_ChIP-Seq_HL-1_Mouse1.05295880
122NANOG_18692474_ChIP-Seq_MESCs_Mouse1.04695761
123KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04141285
124ZFP281_27345836_Chip-Seq_ESCs_Mouse1.03955137
125FOXO3_23340844_ChIP-Seq_DLD1_Human1.03814315
126SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.03806017
127KDM5A_27292631_Chip-Seq_BREAST_Human1.03609580
128JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.03300128
129KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.03106113
130ELK3_25401928_ChIP-Seq_HUVEC_Human1.01332525
131ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.00124111
132RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.00117956
133ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.99825808
134POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.99825542
135LXR_22158963_ChIP-Seq_LIVER_Mouse0.99729145
136TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99679772
137TP53_18474530_ChIP-ChIP_U2OS_Human0.99352381
138ZNF217_24962896_ChIP-Seq_MCF-7_Human0.98889079
139HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98520501
140FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.98286825
141SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.96896308
142GABP_19822575_ChIP-Seq_HepG2_Human0.95070030
143CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93671831
144GABP_17652178_ChIP-ChIP_JURKAT_Human0.92426340
145SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.92288582
146SOX2_27498859_Chip-Seq_STOMACH_Mouse0.89521030
147DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89227662

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010030_abnormal_orbit_morphology3.54243375
2MP0000579_abnormal_nail_morphology3.11517021
3MP0003705_abnormal_hypodermis_morpholog2.89288077
4MP0004957_abnormal_blastocyst_morpholog2.72417415
5MP0010352_gastrointestinal_tract_polyps2.65987701
6MP0003941_abnormal_skin_development2.64201021
7MP0000537_abnormal_urethra_morphology2.56770725
8MP0003111_abnormal_nucleus_morphology2.55477068
9MP0003693_abnormal_embryo_hatching2.52132263
10MP0009053_abnormal_anal_canal2.47931154
11MP0010094_abnormal_chromosome_stability2.23001669
12MP0003077_abnormal_cell_cycle2.16310724
13MP0003950_abnormal_plasma_membrane2.16129674
14MP0005360_urolithiasis2.00518410
15MP0003283_abnormal_digestive_organ1.96783309
16MP0003566_abnormal_cell_adhesion1.92543709
17MP0003123_paternal_imprinting1.92512366
18MP0004272_abnormal_basement_membrane1.91982166
19MP0005275_abnormal_skin_tensile1.90728791
20MP0010234_abnormal_vibrissa_follicle1.89603409
21MP0000566_synostosis1.89538517
22MP0001730_embryonic_growth_arrest1.88251813
23MP0005076_abnormal_cell_differentiation1.86181364
24MP0005623_abnormal_meninges_morphology1.85380633
25MP0003119_abnormal_digestive_system1.84519769
26MP0008932_abnormal_embryonic_tissue1.80598629
27MP0002084_abnormal_developmental_patter1.79582332
28MP0004133_heterotaxia1.79552527
29MP0008007_abnormal_cellular_replicative1.76545117
30MP0008438_abnormal_cutaneous_collagen1.72104122
31MP0000350_abnormal_cell_proliferation1.70591326
32MP0002085_abnormal_embryonic_tissue1.70068891
33MP0005380_embryogenesis_phenotype1.69370141
34MP0001672_abnormal_embryogenesis/_devel1.69370141
35MP0008057_abnormal_DNA_replication1.68170247
36MP0001293_anophthalmia1.67505990
37MP0004197_abnormal_fetal_growth/weight/1.67313451
38MP0002089_abnormal_postnatal_growth/wei1.63311542
39MP0010368_abnormal_lymphatic_system1.56842713
40MP0001849_ear_inflammation1.55567433
41MP0003984_embryonic_growth_retardation1.53119520
42MP0001299_abnormal_eye_distance/1.53079195
43MP0001697_abnormal_embryo_size1.52961374
44MP0002796_impaired_skin_barrier1.52127129
45MP0002088_abnormal_embryonic_growth/wei1.51817024
46MP0003937_abnormal_limbs/digits/tail_de1.50850803
47MP0002086_abnormal_extraembryonic_tissu1.49405046
48MP0003890_abnormal_embryonic-extraembry1.47028732
49MP0005023_abnormal_wound_healing1.46616758
50MP0002653_abnormal_ependyma_morphology1.44174813
51MP0002249_abnormal_larynx_morphology1.41476415
52MP0002111_abnormal_tail_morphology1.40785478
53MP0009780_abnormal_chondrocyte_physiolo1.40184087
54MP0000428_abnormal_craniofacial_morphol1.39699219
55MP0005501_abnormal_skin_physiology1.35482579
56MP0005409_darkened_coat_color1.33221479
57MP0005197_abnormal_uvea_morphology1.32590658
58MP0003115_abnormal_respiratory_system1.31948086
59MP0003122_maternal_imprinting1.31546592
60MP0000762_abnormal_tongue_morphology1.31484426
61MP0000467_abnormal_esophagus_morphology1.30676820
62MP0002697_abnormal_eye_size1.29887943
63MP0003385_abnormal_body_wall1.27418569
64MP0002060_abnormal_skin_morphology1.26268792
65MP0002080_prenatal_lethality1.24765443
66MP0003755_abnormal_palate_morphology1.24550256
67MP0002282_abnormal_trachea_morphology1.24471253
68MP0002092_abnormal_eye_morphology1.24454526
69MP0000432_abnormal_head_morphology1.20466453
70MP0006054_spinal_hemorrhage1.18918786
71MP0003942_abnormal_urinary_system1.17965369
72MP0000383_abnormal_hair_follicle1.17546937
73MP0003567_abnormal_fetal_cardiomyocyte1.15664014
74MP0001286_abnormal_eye_development1.15247098
75MP0010678_abnormal_skin_adnexa1.14332657
76MP0010307_abnormal_tumor_latency1.13991282
77MP0008058_abnormal_DNA_repair1.13718694
78MP0000049_abnormal_middle_ear1.12644586
79MP0002234_abnormal_pharynx_morphology1.12541181
80MP0001661_extended_life_span1.11237354
81MP0003453_abnormal_keratinocyte_physiol1.10979422
82MP0003935_abnormal_craniofacial_develop1.10472795
83MP0005367_renal/urinary_system_phenotyp1.08411039
84MP0000516_abnormal_urinary_system1.08411039
85MP0002233_abnormal_nose_morphology1.06584717
86MP0000733_abnormal_muscle_development1.05963830
87MP0005508_abnormal_skeleton_morphology1.05475085
88MP0003786_premature_aging1.05062770
89MP0004264_abnormal_extraembryonic_tissu1.04555014
90MP0002932_abnormal_joint_morphology1.03690734
91MP0002098_abnormal_vibrissa_morphology1.03217852
92MP0003315_abnormal_perineum_morphology1.03165136
93MP0002938_white_spotting1.02763570
94MP0001915_intracranial_hemorrhage1.02045267
95MP0000767_abnormal_smooth_muscle1.02032867
96MP0005257_abnormal_intraocular_pressure1.01810781
97MP0000534_abnormal_ureter_morphology1.01289332
98MP0002254_reproductive_system_inflammat1.00887354
99MP0002896_abnormal_bone_mineralization1.00270394
100MP0003121_genomic_imprinting1.00263751
101MP0002877_abnormal_melanocyte_morpholog0.99241148
102MP0009697_abnormal_copulation0.97174020
103MP0002925_abnormal_cardiovascular_devel0.93702063
104MP0001216_abnormal_epidermal_layer0.89872613
105MP0004858_abnormal_nervous_system0.89276160
106MP0010771_integument_phenotype0.88554007
107MP0000377_abnormal_hair_follicle0.88542647
108MP0008789_abnormal_olfactory_epithelium0.87949835
109MP0001340_abnormal_eyelid_morphology0.87839023
110MP0001958_emphysema0.87507563
111MP0009250_abnormal_appendicular_skeleto0.87000434
112MP0000003_abnormal_adipose_tissue0.86676792
113MP0005193_abnormal_anterior_eye0.84499249
114MP0002116_abnormal_craniofacial_bone0.84104880
115MP0000751_myopathy0.83829626
116MP0000462_abnormal_digestive_system0.83734315
117MP0009672_abnormal_birth_weight0.81409779
118MP0009703_decreased_birth_body0.79999785
119MP0005248_abnormal_Harderian_gland0.79214819
120MP0000013_abnormal_adipose_tissue0.78886094
121MP0001346_abnormal_lacrimal_gland0.78455581
122MP0003091_abnormal_cell_migration0.77249288
123MP0009384_cardiac_valve_regurgitation0.77116134
124MP0001243_abnormal_dermal_layer0.76811158
125MP0003936_abnormal_reproductive_system0.76681027
126MP0004233_abnormal_muscle_weight0.76666955
127MP0006292_abnormal_olfactory_placode0.76524767
128MP0000647_abnormal_sebaceous_gland0.75808766
129MP0003861_abnormal_nervous_system0.75284734
130MP0002114_abnormal_axial_skeleton0.73998792

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)3.64459650
2Selective tooth agenesis (HP:0001592)3.60901283
3Protrusio acetabuli (HP:0003179)3.25142045
4Arterial tortuosity (HP:0005116)3.06615425
5Ependymoma (HP:0002888)3.05579354
6Missing ribs (HP:0000921)2.84895164
7Absent radius (HP:0003974)2.84536075
8Vascular tortuosity (HP:0004948)2.83755271
9Shallow orbits (HP:0000586)2.82758804
10Premature rupture of membranes (HP:0001788)2.78036991
11Aplasia involving forearm bones (HP:0009822)2.71925189
12Absent forearm bone (HP:0003953)2.71925189
13Esophageal atresia (HP:0002032)2.68526807
14Atrophic scars (HP:0001075)2.67415844
15Aplasia/hypoplasia of the humerus (HP:0006507)2.65022825
16Short humerus (HP:0005792)2.64149278
17Short nail (HP:0001799)2.57457050
18Deviation of the thumb (HP:0009603)2.52802305
19Trismus (HP:0000211)2.50205318
20Aortic dissection (HP:0002647)2.50035211
21Milia (HP:0001056)2.46556005
22Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.46366324
23Short 4th metacarpal (HP:0010044)2.46366324
24Abnormality of carpal bone ossification (HP:0006257)2.43594047
25Fused cervical vertebrae (HP:0002949)2.43479345
26Neonatal short-limb short stature (HP:0008921)2.43218769
27Flat acetabular roof (HP:0003180)2.40344021
28Ankle contracture (HP:0006466)2.39049542
29Colon cancer (HP:0003003)2.38392478
30Plantar hyperkeratosis (HP:0007556)2.37185599
31Abnormal ossification of hand bones (HP:0005921)2.35156771
32Alopecia of scalp (HP:0002293)2.34456448
33Cardiovascular calcification (HP:0011915)2.33870109
34Abnormality of the labia minora (HP:0012880)2.33339353
35Proximal placement of thumb (HP:0009623)2.30132598
36Breast hypoplasia (HP:0003187)2.28410813
37Thick nail (HP:0001805)2.26382117
38Medulloblastoma (HP:0002885)2.26336003
39Abnormality of the astrocytes (HP:0100707)2.25079658
40Astrocytoma (HP:0009592)2.25079658
41Vascular calcification (HP:0004934)2.23925833
42Advanced eruption of teeth (HP:0006288)2.22793329
4311 pairs of ribs (HP:0000878)2.22417827
44Abnormality of nail color (HP:0100643)2.21009604
45Abnormal number of incisors (HP:0011064)2.16760164
46Mitral stenosis (HP:0001718)2.16737699
47Abnormality of dentin (HP:0010299)2.16039377
48Abnormality of the acetabulum (HP:0003170)2.08985803
49Abnormality of the calcaneus (HP:0008364)2.08780679
50Abdominal situs inversus (HP:0003363)2.08690209
51Abnormality of abdominal situs (HP:0011620)2.08690209
52Hypercholesterolemia (HP:0003124)2.05866814
53Vertebral arch anomaly (HP:0008438)2.05502780
54Vertebral compression fractures (HP:0002953)2.05429404
55Reticulocytopenia (HP:0001896)2.03882574
56Synostosis of carpal bones (HP:0005048)2.03793432
57Bladder diverticulum (HP:0000015)2.01868350
58Skull defect (HP:0001362)1.98405297
59Prolonged partial thromboplastin time (HP:0003645)1.97713938
60Rib fusion (HP:0000902)1.97549234
61High anterior hairline (HP:0009890)1.97298796
62Atresia of the external auditory canal (HP:0000413)1.95699941
63Popliteal pterygium (HP:0009756)1.95388943
64Fragile nails (HP:0001808)1.94370898
65Microglossia (HP:0000171)1.93627451
66Shawl scrotum (HP:0000049)1.93139690
67Small epiphyses (HP:0010585)1.92219112
68Coronal craniosynostosis (HP:0004440)1.92083365
69Supernumerary spleens (HP:0009799)1.92035601
70Hyperacusis (HP:0010780)1.90219192
71Neoplasm of the oral cavity (HP:0100649)1.89993511
72Broad face (HP:0000283)1.89948205
73Patellar aplasia (HP:0006443)1.88616709
74Ridged nail (HP:0001807)1.88418161
75Abnormal hand bone ossification (HP:0010660)1.88231159
76Preaxial foot polydactyly (HP:0001841)1.87962803
77Vertebral fusion (HP:0002948)1.86639094
78Bowing of the arm (HP:0006488)1.86335348
79Bowed forearm bones (HP:0003956)1.86335348
80Cerebral aneurysm (HP:0004944)1.86276652
81Abnormality of oral frenula (HP:0000190)1.85960249
82Abnormality of the distal phalanx of the thumb (HP:0009617)1.85653956
83Gastrointestinal carcinoma (HP:0002672)1.85380083
84Malignant gastrointestinal tract tumors (HP:0006749)1.85380083
85Hypoplasia of the capital femoral epiphysis (HP:0003090)1.84960836
86Aortic aneurysm (HP:0004942)1.84313823
87Ankyloglossia (HP:0010296)1.84278237
88Glioma (HP:0009733)1.84158362
89Abnormality of the antihelix (HP:0009738)1.84142182
90Asymmetry of the thorax (HP:0001555)1.83666977
91Pseudobulbar signs (HP:0002200)1.83314318
92Chromosomal breakage induced by crosslinking agents (HP:0003221)1.82657839
93Genu recurvatum (HP:0002816)1.82218305
94Wormian bones (HP:0002645)1.81721955
95Broad thumb (HP:0011304)1.81559351
96Rhabdomyosarcoma (HP:0002859)1.81550084
97Increased connective tissue (HP:0009025)1.81386695
98Back pain (HP:0003418)1.81385846
99Ulnar bowing (HP:0003031)1.79733781
100Bronchomalacia (HP:0002780)1.78904111
101Wrist flexion contracture (HP:0001239)1.78274553
102Abnormality of the 4th metacarpal (HP:0010012)1.78130800
103Right ventricular cardiomyopathy (HP:0011663)1.78011179
104Neonatal death (HP:0003811)1.77872056
105Aplasia/Hypoplasia of the patella (HP:0006498)1.77538339
106Biliary tract neoplasm (HP:0100574)1.77335870
107Abnormality of the salivary glands (HP:0010286)1.77229084
108Blue sclerae (HP:0000592)1.76705481
109Carpal synostosis (HP:0009702)1.76697579
110Hypobetalipoproteinemia (HP:0003563)1.76581899
111Nail dystrophy (HP:0008404)1.76464666
112Limited elbow extension (HP:0001377)1.75553426
113Chromsome breakage (HP:0040012)1.75543613
114Soft skin (HP:0000977)1.75480724
115Abnormality of the Achilles tendon (HP:0005109)1.75062088
116Abnormal delivery (HP:0001787)1.74737685
117Absent epiphyses (HP:0010577)1.74552338
118Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.74552338
119Renal duplication (HP:0000075)1.73757622
120Neoplasm of striated muscle (HP:0009728)1.73739183
121Absent thumb (HP:0009777)1.73535182
122Gastrointestinal atresia (HP:0002589)1.73255632
123Onycholysis (HP:0001806)1.72821930
124Absent eyelashes (HP:0000561)1.72034270
125Mitral valve prolapse (HP:0001634)1.71830727
126Abnormality of the nasal septum (HP:0000419)1.70464302
127Spinal rigidity (HP:0003306)1.69864058
128Aplasia involving bones of the extremities (HP:0009825)1.68901523
129Aplasia involving bones of the upper limbs (HP:0009823)1.68901523
130Aplasia of the phalanges of the hand (HP:0009802)1.68901523
131Short phalanx of the thumb (HP:0009660)1.68224649
132Neoplasm of the pancreas (HP:0002894)1.68036839
133Preauricular skin tag (HP:0000384)1.67772088
134Natal tooth (HP:0000695)1.67660566
135Arnold-Chiari malformation (HP:0002308)1.67473288
136Coxa vara (HP:0002812)1.67041270
137Short 1st metacarpal (HP:0010034)1.66469133
138Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.66469133
139Biconcave vertebral bodies (HP:0004586)1.66391135
140Increased nuchal translucency (HP:0010880)1.65887213
141Radial bowing (HP:0002986)1.65673016
142Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.65241630
143Abnormality of the lacrimal duct (HP:0011481)1.65163273
144Skin tags (HP:0010609)1.64352095
145Abnormality of the distal phalanges of the toes (HP:0010182)1.63751497
146Abnormality of the proximal phalanges of the hand (HP:0009834)1.63461031
147Partial duplication of the phalanx of hand (HP:0009999)1.63387300
148Pterygium (HP:0001059)1.63076480
149Vertebral clefting (HP:0008428)1.62854576
150Stenosis of the external auditory canal (HP:0000402)1.62554787
151Vertebral hypoplasia (HP:0008417)1.62275618
152Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.62275618
153Fragile skin (HP:0001030)1.61744611
154Achilles tendon contracture (HP:0001771)1.61410573
155Hypoplasia of dental enamel (HP:0006297)1.61264952
156Aplasia/Hypoplasia of the sternum (HP:0006714)1.61149032
157Abnormal tarsal ossification (HP:0008369)1.60893247
158Palmoplantar hyperkeratosis (HP:0000972)1.60623847
159Partial duplication of thumb phalanx (HP:0009944)1.59906228
160Abnormal vertebral ossification (HP:0100569)1.59576104
161Supernumerary ribs (HP:0005815)1.59425220
162Broad toe (HP:0001837)1.58847428
163Rhizomelia (HP:0008905)1.58613913
164Abnormal foot bone ossification (HP:0010675)1.57719887
165Myelomeningocele (HP:0002475)1.56786880
166Breech presentation (HP:0001623)1.56376149
167Spastic diplegia (HP:0001264)1.56257335
168Nasolacrimal duct obstruction (HP:0000579)1.55881671
169Focal segmental glomerulosclerosis (HP:0000097)1.55753330
170Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.55494695
171Cervical subluxation (HP:0003308)1.55222249
172Osteolytic defects of the hand bones (HP:0009699)1.54484549
173Osteolytic defects of the phalanges of the hand (HP:0009771)1.54484549
174Abnormality of the common coagulation pathway (HP:0010990)1.54267892

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA24.87793399
2CDK123.93097155
3MST1R3.68702586
4BUB13.62426333
5WEE12.70809785
6RPS6KB22.55567695
7LATS12.55272314
8NTRK12.54730229
9CDC72.54130209
10SIK12.32716318
11TTK2.23115052
12LATS22.22115840
13NEK22.09326977
14TTN2.04693530
15FGFR41.94209960
16EEF2K1.92765488
17CDK71.91260215
18STK38L1.80921559
19NEK11.77614933
20PAK41.72805331
21SMG11.69894258
22EPHB21.69738255
23PASK1.68514461
24TSSK61.57640927
25MAP3K101.56824304
26PLK11.49383768
27TAF11.49112200
28MAPKAPK31.46607718
29PKN21.43984061
30MYLK1.42953823
31BRD41.40129494
32FGFR11.33842543
33IRAK31.33127551
34STK101.31814823
35AURKB1.30602806
36PBK1.28352993
37MAP3K81.27875030
38PDGFRA1.27695168
39MTOR1.27532472
40MET1.24650054
41RPS6KA41.23414085
42CDK41.20610481
43TGFBR11.20467843
44DDR21.19779178
45LMTK21.19198657
46MKNK11.16883317
47DYRK31.14379506
48TESK21.13848011
49BMX1.12284107
50CHEK21.12085282
51TLK11.11552658
52SRPK11.10738071
53PLK31.10345146
54PAK21.09644101
55CHEK11.08205947
56STK31.07689328
57BRSK21.06952825
58ATR1.05570712
59PTK21.03764613
60NEK91.01556898
61AURKA0.99617526
62TESK10.99303163
63MAP3K120.96125245
64MAP3K30.96076900
65ALK0.94339906
66ZAK0.90130526
67PRKCI0.89878589
68CDK60.89431689
69PTK60.88611571
70MAP3K90.85394620
71ARAF0.82764251
72TRIB30.82073804
73ICK0.81890183
74FER0.80522826
75AKT20.79794534
76FLT30.78441758
77FGFR20.76082346
78CDK20.75707113
79TGFBR20.74260657
80RIPK10.74173790
81MELK0.73453053
82STK380.73121706
83LRRK20.72747881
84PIM20.72675905
85MKNK20.71403772
86MUSK0.69339510
87STK40.67959684
88ATM0.67837870
89ACVR1B0.67624001
90VRK20.67448760
91PAK10.64893005
92EIF2AK10.62458791
93AKT30.60116482
94PDGFRB0.60009186
95MAP3K20.58994131
96MOS0.58737390
97PLK40.58255463
98PIM10.58082413
99MAP2K20.57683379
100ERBB40.57244740
101TYRO30.54379726
102ROCK20.53956172
103CSNK1E0.53930764
104EPHB10.53474074
105DMPK0.52120137
106FGFR30.51358008
107STK240.50760502
108CDK10.50422992
109SCYL20.48813094
110BCR0.47249250
111CDK80.42255308
112NME20.42180780
113RPS6KA20.41981912
114LIMK10.41715391
115CSNK1D0.41557537
116CDK90.41531044
117KSR20.41360995
118BRSK10.40081014
119CDC42BPA0.38932736
120ROCK10.38652372
121CSNK2A20.38595153
122KDR0.38530165
123BRAF0.38484115
124MAP2K30.38047201
125KSR10.37749324
126MAP3K110.36903947
127MAPK10.36349193
128ERN10.35189737
129CAMK1G0.34403596
130PIK3CA0.33887644
131ERBB20.33817549
132VRK10.33643467
133PRKDC0.33152427
134PNCK0.33004976
135AKT10.32442667
136WNK40.31448545
137MAP2K10.31374444
138ILK0.31167994
139RPS6KA10.30375242

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.34347933
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.29797897
3Mismatch repair_Homo sapiens_hsa034303.12912319
4RNA transport_Homo sapiens_hsa030133.01729587
5Basal cell carcinoma_Homo sapiens_hsa052172.82101760
6Spliceosome_Homo sapiens_hsa030402.79083184
7One carbon pool by folate_Homo sapiens_hsa006702.77973663
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.61697191
9Cell cycle_Homo sapiens_hsa041102.55562315
10* Hippo signaling pathway_Homo sapiens_hsa043902.26738436
11Hedgehog signaling pathway_Homo sapiens_hsa043402.23611978
12Nucleotide excision repair_Homo sapiens_hsa034202.14374786
13p53 signaling pathway_Homo sapiens_hsa041152.09380182
14Base excision repair_Homo sapiens_hsa034102.09324764
15Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.94938992
16mRNA surveillance pathway_Homo sapiens_hsa030151.94777412
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.92665893
18Complement and coagulation cascades_Homo sapiens_hsa046101.91160120
19RNA polymerase_Homo sapiens_hsa030201.90574954
20Steroid biosynthesis_Homo sapiens_hsa001001.90318394
21Ribosome_Homo sapiens_hsa030101.89736058
22Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.89252416
23Adherens junction_Homo sapiens_hsa045201.81310094
24Homologous recombination_Homo sapiens_hsa034401.77880166
25Small cell lung cancer_Homo sapiens_hsa052221.68922920
26Bladder cancer_Homo sapiens_hsa052191.67689463
27MicroRNAs in cancer_Homo sapiens_hsa052061.67425335
28ECM-receptor interaction_Homo sapiens_hsa045121.65292624
29TGF-beta signaling pathway_Homo sapiens_hsa043501.63938719
30Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.54253572
31Fanconi anemia pathway_Homo sapiens_hsa034601.53519501
32Notch signaling pathway_Homo sapiens_hsa043301.47548455
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.41643470
34Tight junction_Homo sapiens_hsa045301.36556379
35Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.35450301
36Systemic lupus erythematosus_Homo sapiens_hsa053221.34924475
37N-Glycan biosynthesis_Homo sapiens_hsa005101.34884098
38Proteoglycans in cancer_Homo sapiens_hsa052051.33329188
39RNA degradation_Homo sapiens_hsa030181.31877410
40Pyrimidine metabolism_Homo sapiens_hsa002401.28486604
41Proteasome_Homo sapiens_hsa030501.26804397
42Arginine biosynthesis_Homo sapiens_hsa002201.26086091
43Basal transcription factors_Homo sapiens_hsa030221.23860123
44Viral carcinogenesis_Homo sapiens_hsa052031.22814856
45Thyroid cancer_Homo sapiens_hsa052161.19568976
46Focal adhesion_Homo sapiens_hsa045101.19071945
47HTLV-I infection_Homo sapiens_hsa051661.17422361
48Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.14184702
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.12188935
50Pyruvate metabolism_Homo sapiens_hsa006201.10235427
51Phenylalanine metabolism_Homo sapiens_hsa003601.10125064
52Biosynthesis of amino acids_Homo sapiens_hsa012301.08971437
53Cyanoamino acid metabolism_Homo sapiens_hsa004601.06834679
54Pathways in cancer_Homo sapiens_hsa052001.03048004
55Wnt signaling pathway_Homo sapiens_hsa043101.03045963
56Pentose and glucuronate interconversions_Homo sapiens_hsa000401.02362358
57Central carbon metabolism in cancer_Homo sapiens_hsa052301.02018009
58Galactose metabolism_Homo sapiens_hsa000521.01478432
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.96366784
60Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.95789525
61Selenocompound metabolism_Homo sapiens_hsa004500.95616078
62Non-homologous end-joining_Homo sapiens_hsa034500.92446384
63Dilated cardiomyopathy_Homo sapiens_hsa054140.88493977
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.88248266
65Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.87234478
66Arginine and proline metabolism_Homo sapiens_hsa003300.85466930
67Sulfur relay system_Homo sapiens_hsa041220.83626512
68Fat digestion and absorption_Homo sapiens_hsa049750.80839782
69Oocyte meiosis_Homo sapiens_hsa041140.78976693
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77971035
71PI3K-Akt signaling pathway_Homo sapiens_hsa041510.76455283
72Epstein-Barr virus infection_Homo sapiens_hsa051690.76081340
73Melanoma_Homo sapiens_hsa052180.75430537
74Glycosaminoglycan degradation_Homo sapiens_hsa005310.74686935
75Amoebiasis_Homo sapiens_hsa051460.74234999
76Colorectal cancer_Homo sapiens_hsa052100.71790094
77Prion diseases_Homo sapiens_hsa050200.70615672
78Bile secretion_Homo sapiens_hsa049760.70048289
79Lysine degradation_Homo sapiens_hsa003100.69982164
80Starch and sucrose metabolism_Homo sapiens_hsa005000.68990601
81Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68838388
82Chronic myeloid leukemia_Homo sapiens_hsa052200.68332911
83Regulation of actin cytoskeleton_Homo sapiens_hsa048100.67651944
84Prostate cancer_Homo sapiens_hsa052150.67360778
85mTOR signaling pathway_Homo sapiens_hsa041500.66507432
86Tyrosine metabolism_Homo sapiens_hsa003500.66301341
87Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63511626
88Fatty acid metabolism_Homo sapiens_hsa012120.62439131
89Histidine metabolism_Homo sapiens_hsa003400.62352910
90Retinol metabolism_Homo sapiens_hsa008300.61677973
91Fatty acid degradation_Homo sapiens_hsa000710.60614011
92Endometrial cancer_Homo sapiens_hsa052130.59582558
93Leukocyte transendothelial migration_Homo sapiens_hsa046700.58824833
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.58719913
95Sphingolipid metabolism_Homo sapiens_hsa006000.58000036
962-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.57981737
97Viral myocarditis_Homo sapiens_hsa054160.57025770
98Apoptosis_Homo sapiens_hsa042100.56597265
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.56553853
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56525568
101Thyroid hormone synthesis_Homo sapiens_hsa049180.56073972
102Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.55468774
103Melanogenesis_Homo sapiens_hsa049160.54783982
104Fatty acid biosynthesis_Homo sapiens_hsa000610.54273512
105Protein digestion and absorption_Homo sapiens_hsa049740.53472451
106Herpes simplex infection_Homo sapiens_hsa051680.53452700
107Vitamin digestion and absorption_Homo sapiens_hsa049770.53059423
108Steroid hormone biosynthesis_Homo sapiens_hsa001400.51215233
109HIF-1 signaling pathway_Homo sapiens_hsa040660.50637621
110Carbon metabolism_Homo sapiens_hsa012000.50200079
111Antigen processing and presentation_Homo sapiens_hsa046120.49954365
112Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49360122
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.48952421
114Primary bile acid biosynthesis_Homo sapiens_hsa001200.48760714
115Purine metabolism_Homo sapiens_hsa002300.48269838
116Rap1 signaling pathway_Homo sapiens_hsa040150.47576144
117Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.47565770
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46073124
119Glutathione metabolism_Homo sapiens_hsa004800.44286709
120Pentose phosphate pathway_Homo sapiens_hsa000300.37405581
121Alcoholism_Homo sapiens_hsa050340.37144357
122Shigellosis_Homo sapiens_hsa051310.36470352
123Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.34386462
124Fructose and mannose metabolism_Homo sapiens_hsa000510.33720838
125Vitamin B6 metabolism_Homo sapiens_hsa007500.30836553
126Renal cell carcinoma_Homo sapiens_hsa052110.29940984
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.28949308
128Legionellosis_Homo sapiens_hsa051340.24754610
129Acute myeloid leukemia_Homo sapiens_hsa052210.24472562
130AMPK signaling pathway_Homo sapiens_hsa041520.22769547
131Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.22285172
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.22173260
133Pancreatic cancer_Homo sapiens_hsa052120.21877877
134Drug metabolism - other enzymes_Homo sapiens_hsa009830.21378048
135Axon guidance_Homo sapiens_hsa043600.20632779
136FoxO signaling pathway_Homo sapiens_hsa040680.19897224

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