AHCTF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* nuclear pore complex assembly (GO:0051292)6.29007888
2* nuclear pore organization (GO:0006999)5.99885282
3mitotic sister chromatid cohesion (GO:0007064)4.97586240
4* pore complex assembly (GO:0046931)4.56808823
5protein localization to kinetochore (GO:0034501)4.51544769
6mitotic nuclear envelope disassembly (GO:0007077)4.43832691
7regulation of histone H3-K9 methylation (GO:0051570)4.33560519
8DNA unwinding involved in DNA replication (GO:0006268)4.20680279
9mitotic chromosome condensation (GO:0007076)4.18879162
10nuclear envelope disassembly (GO:0051081)4.17034854
11membrane disassembly (GO:0030397)4.17034854
12regulation of RNA export from nucleus (GO:0046831)4.16943837
13pre-miRNA processing (GO:0031054)4.14475010
14protein localization to chromosome, centromeric region (GO:0071459)4.13572085
15sister chromatid segregation (GO:0000819)4.01800308
16DNA replication-dependent nucleosome assembly (GO:0006335)4.00484180
17DNA replication-dependent nucleosome organization (GO:0034723)4.00484180
18monoubiquitinated protein deubiquitination (GO:0035520)3.88676774
19regulation of spindle organization (GO:0090224)3.87658591
20negative regulation of histone methylation (GO:0031061)3.87086182
21DNA duplex unwinding (GO:0032508)3.84233732
22DNA geometric change (GO:0032392)3.83127837
23mitotic metaphase plate congression (GO:0007080)3.79378638
24cytoplasmic mRNA processing body assembly (GO:0033962)3.78407201
25mitotic sister chromatid segregation (GO:0000070)3.77982080
26regulation of centriole replication (GO:0046599)3.75952347
27folic acid-containing compound biosynthetic process (GO:0009396)3.75045758
28kinetochore organization (GO:0051383)3.73790018
29positive regulation of mitotic sister chromatid separation (GO:1901970)3.71032615
30positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.71032615
31positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.71032615
32heterochromatin organization (GO:0070828)3.65521820
33chromatin assembly (GO:0031497)3.60826187
34regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.58532690
35dosage compensation (GO:0007549)3.57588643
36translesion synthesis (GO:0019985)3.57440502
37regulation of mitotic spindle organization (GO:0060236)3.57383064
38negative regulation of DNA repair (GO:0045738)3.54907756
39regulation of histone H3-K27 methylation (GO:0061085)3.54627079
40positive regulation of chromosome segregation (GO:0051984)3.53059016
41metaphase plate congression (GO:0051310)3.51160501
42protein export from nucleus (GO:0006611)3.50070967
43DNA replication initiation (GO:0006270)3.49670863
44NLS-bearing protein import into nucleus (GO:0006607)3.48978981
45DNA topological change (GO:0006265)3.46441931
46regulation of centrosome cycle (GO:0046605)3.45961461
47protein K6-linked ubiquitination (GO:0085020)3.42960735
48histone H3-K9 demethylation (GO:0033169)3.42530167
49regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.42111694
50meiotic chromosome segregation (GO:0045132)3.37896474
51chromatin remodeling at centromere (GO:0031055)3.34950578
52chromatin assembly or disassembly (GO:0006333)3.33073273
53gene silencing by RNA (GO:0031047)3.31749959
54histone H2A monoubiquitination (GO:0035518)3.29053123
55DNA synthesis involved in DNA repair (GO:0000731)3.28893719
56IMP biosynthetic process (GO:0006188)3.28823469
57histone H3-K36 demethylation (GO:0070544)3.28748730
58DNA conformation change (GO:0071103)3.28685807
59phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.28126874
60regulation of DNA endoreduplication (GO:0032875)3.27444725
61regulation of sister chromatid cohesion (GO:0007063)3.27061603
62regulation of posttranscriptional gene silencing (GO:0060147)3.26555921
63regulation of gene silencing by miRNA (GO:0060964)3.26555921
64regulation of gene silencing by RNA (GO:0060966)3.26555921
65protein localization to chromosome (GO:0034502)3.26164803
66histone exchange (GO:0043486)3.25174716
67DNA replication-independent nucleosome assembly (GO:0006336)3.22673745
68DNA replication-independent nucleosome organization (GO:0034724)3.22673745
69sister chromatid cohesion (GO:0007062)3.21911379
70regulation of nucleobase-containing compound transport (GO:0032239)3.20571205
71chromosome condensation (GO:0030261)3.19259464
72nuclear envelope organization (GO:0006998)3.18716515
73regulation of chromosome segregation (GO:0051983)3.17323083
74CENP-A containing nucleosome assembly (GO:0034080)3.14277170
75peptidyl-lysine dimethylation (GO:0018027)3.14224480
76* nucleus organization (GO:0006997)3.10665943
77regulation of centrosome duplication (GO:0010824)3.07307834
78DNA packaging (GO:0006323)3.07159780
79embryonic process involved in female pregnancy (GO:0060136)3.06778399
80establishment of chromosome localization (GO:0051303)3.06628815
81attachment of spindle microtubules to kinetochore (GO:0008608)3.05434825
82regulation of mitotic metaphase/anaphase transition (GO:0030071)3.03356839
83spindle checkpoint (GO:0031577)3.00616873
84nucleobase biosynthetic process (GO:0046112)3.00377475
85kinetochore assembly (GO:0051382)2.99847987
86regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.98892837
87microtubule depolymerization (GO:0007019)2.97801200
88DNA replication checkpoint (GO:0000076)2.97637856
89regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.96117472
90DNA strand elongation involved in DNA replication (GO:0006271)2.95844388
91ATP-dependent chromatin remodeling (GO:0043044)2.94436662
92double-strand break repair via nonhomologous end joining (GO:0006303)2.94191258
93non-recombinational repair (GO:0000726)2.94191258
94chromosome segregation (GO:0007059)2.93798945
95positive regulation of cell cycle checkpoint (GO:1901978)2.92845650
96* mRNA transport (GO:0051028)2.92338112
97regulation of translational fidelity (GO:0006450)2.92250787
98synaptonemal complex assembly (GO:0007130)2.90447496
99histone lysine demethylation (GO:0070076)2.90410241
100histone mRNA catabolic process (GO:0071044)2.89572116
101regulation of helicase activity (GO:0051095)2.89276761
102negative regulation of chromosome segregation (GO:0051985)2.89092283
103regulation of mitotic sister chromatid separation (GO:0010965)2.88438641
104regulation of mitotic sister chromatid segregation (GO:0033047)2.88438641
105regulation of sister chromatid segregation (GO:0033045)2.88438641
106spindle assembly checkpoint (GO:0071173)2.87627775
107postreplication repair (GO:0006301)2.86252073
108paraxial mesoderm development (GO:0048339)2.85560417
109ribosome assembly (GO:0042255)2.85172409
110mitotic spindle checkpoint (GO:0071174)2.83592712
111negative regulation of mitotic sister chromatid separation (GO:2000816)2.83384223
112negative regulation of mitotic sister chromatid segregation (GO:0033048)2.83384223
113negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.83384223
114negative regulation of sister chromatid segregation (GO:0033046)2.83384223
115DNA strand elongation (GO:0022616)2.83222709
116IMP metabolic process (GO:0046040)2.82693442
117RNA stabilization (GO:0043489)2.81250390
118mRNA stabilization (GO:0048255)2.81250390
119histone demethylation (GO:0016577)2.80322003
120nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.73630532
121protein targeting to Golgi (GO:0000042)2.70519971
122establishment of protein localization to Golgi (GO:0072600)2.68741271
123positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.65834534
124retrograde transport, vesicle recycling within Golgi (GO:0000301)2.65673063
125peptidyl-threonine phosphorylation (GO:0018107)2.59918792
126peptidyl-threonine modification (GO:0018210)2.59207359
127N-terminal protein amino acid acetylation (GO:0006474)2.58710873
128iron ion import (GO:0097286)2.57977449
129histone phosphorylation (GO:0016572)2.57657385
130COPII vesicle coating (GO:0048208)2.53300920
131regulation of histone methylation (GO:0031060)2.51912695
132histone H2B ubiquitination (GO:0033523)2.51236582
133cellular protein complex localization (GO:0034629)2.50893386
134glucocorticoid receptor signaling pathway (GO:0042921)2.50179567
135positive regulation of protein import into nucleus, translocation (GO:0033160)2.49926464
136hypotonic response (GO:0006971)2.48995734
137definitive hemopoiesis (GO:0060216)2.48799068
138peptidyl-lysine trimethylation (GO:0018023)2.47931863
139hepatocyte apoptotic process (GO:0097284)2.47020106
140corticosteroid receptor signaling pathway (GO:0031958)2.46865479
141regulation of double-strand break repair (GO:2000779)2.46024869
142mitotic G2/M transition checkpoint (GO:0044818)2.45513117

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.79520898
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.43659343
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.47012343
4MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.42695304
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.29120407
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.27620381
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.24872518
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.06794250
9AR_21909140_ChIP-Seq_LNCAP_Human2.63615518
10* SALL1_21062744_ChIP-ChIP_HESCs_Human2.56517631
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.53331856
12MYC_19079543_ChIP-ChIP_MESCs_Mouse2.40494961
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.18756680
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.14387382
15* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.07993150
16MYC_22102868_ChIP-Seq_BL_Human2.03811845
17E2F7_22180533_ChIP-Seq_HELA_Human11.0280360
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.99464200
19MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.94423202
20MYCN_18555785_ChIP-Seq_MESCs_Mouse1.87720600
21NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.85213828
22SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.82788512
23BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.82207450
24* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.78389199
25SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.78183262
26GATA1_22025678_ChIP-Seq_K562_Human1.74160999
27MYB_21317192_ChIP-Seq_ERMYB_Mouse1.65463701
28* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.62879895
29ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.60169990
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56807036
31XRN2_22483619_ChIP-Seq_HELA_Human1.55599656
32TP63_19390658_ChIP-ChIP_HaCaT_Human1.55453451
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.55165528
34KDM5A_27292631_Chip-Seq_BREAST_Human1.45572234
35* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.44750480
36STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.42251164
37SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.42112746
38SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.42112746
39KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.41500964
40FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.41358308
41VDR_23849224_ChIP-Seq_CD4+_Human1.40491404
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40417760
43MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34095831
44SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.32349989
45NANOG_18555785_ChIP-Seq_MESCs_Mouse1.31442905
46FOXP3_21729870_ChIP-Seq_TREG_Human1.30777790
47STAT3_1855785_ChIP-Seq_MESCs_Mouse1.29715305
48CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.28659540
49ELK1_19687146_ChIP-ChIP_HELA_Human1.27965764
50SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27738168
51CIITA_25753668_ChIP-Seq_RAJI_Human1.27438488
52SMAD_19615063_ChIP-ChIP_OVARY_Human1.26904685
53* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.26901690
54PADI4_21655091_ChIP-ChIP_MCF-7_Human1.26507768
55CLOCK_20551151_ChIP-Seq_293T_Human1.25704020
56WT1_19549856_ChIP-ChIP_CCG9911_Human1.25281685
57DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.24094362
58* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.23471296
59EST1_17652178_ChIP-ChIP_JURKAT_Human1.22623144
60ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20475085
61CREB1_15753290_ChIP-ChIP_HEK293T_Human1.17449606
62* BRD4_25478319_ChIP-Seq_HGPS_Human1.17129640
63ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17015137
64TTF2_22483619_ChIP-Seq_HELA_Human1.16648214
65* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.16084800
66TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.16066396
67CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.15868907
68HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.12867453
69CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10641654
70* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10220266
71* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.08640364
72CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07960038
73HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.07233726
74KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06205763
75FOXO3_23340844_ChIP-Seq_DLD1_Human1.05995410
76* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.05629804
77* ETS1_20019798_ChIP-Seq_JURKAT_Human1.05105208
78E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05004255
79POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.04958186
80TP63_17297297_ChIP-ChIP_HaCaT_Human1.04837932
81DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04151269
82E2F1_18555785_ChIP-Seq_MESCs_Mouse1.02293566
83DCP1A_22483619_ChIP-Seq_HELA_Human1.02004694
84GABP_19822575_ChIP-Seq_HepG2_Human1.01653983
85TFEB_21752829_ChIP-Seq_HELA_Human1.01233600
86HOXB4_20404135_ChIP-ChIP_EML_Mouse1.00760081
87* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.00488944
88SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.99759938
89POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98840728
90TCF4_18268006_ChIP-ChIP_LS174T_Human0.98638185
91NANOG_21062744_ChIP-ChIP_HESCs_Human0.97208921
92PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.96402049
93FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.95589993
94BRD4_27068464_Chip-Seq_AML-cells_Mouse0.95050247
95* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.94150678
96* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.93651653
97SOX9_24532713_ChIP-Seq_HFSC_Mouse0.93349503
98TCF3_18692474_ChIP-Seq_MESCs_Mouse0.93037649
99CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.92774336
100PPAR_26484153_Chip-Seq_NCI-H1993_Human0.92522606
101* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.91889037
102KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.91867712
103KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.91867712
104KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.91867712
105* MYB_26560356_Chip-Seq_TH1_Human0.90695153
106NOTCH1_21737748_ChIP-Seq_TLL_Human0.90444081
107FOXM1_26456572_ChIP-Seq_MCF-7_Human0.90378738
108TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89655017
109* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.89446928
110* GATA6_25053715_ChIP-Seq_YYC3_Human0.88915092
111CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.88452709
112TCF7_22412390_ChIP-Seq_EML_Mouse0.88149303
113KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.87703996
114SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.87336716
115STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.87129502
116SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.86958418
117PU_27001747_Chip-Seq_BMDM_Mouse0.86956936
118EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.86443217
119FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.85913035
120PKCTHETA_26484144_Chip-Seq_BREAST_Human0.85488468
121CHD1_26751641_Chip-Seq_LNCaP_Human0.85407314
122SOX2_27498859_Chip-Seq_STOMACH_Mouse0.85026703
123* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.84893996
124CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84455158
125FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.82457325
126ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.82308290
127NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.82182892
128ATF3_27146783_Chip-Seq_COLON_Human0.80764474
129MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.79605161
130* UBF1/2_26484160_Chip-Seq_HMECs_Human0.79172747
131SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.78961884
132GABP_17652178_ChIP-ChIP_JURKAT_Human0.78860453
133TCF3_18692474_ChIP-Seq_MEFs_Mouse0.77813906
134* SOX17_20123909_ChIP-Seq_XEN_Mouse0.77614032
135NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.76824408
136CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.76444450
137* NCOR1_26117541_ChIP-Seq_K562_Human0.76200390
138ERG_20887958_ChIP-Seq_HPC-7_Mouse0.72410572
139SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.71751273
140FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.71722920
141MYB_26560356_Chip-Seq_TH2_Human0.71648041
142KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.71575485
143MYC_18940864_ChIP-ChIP_HL60_Human0.70908915
144KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.69264045
145FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.68112616
146JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.67993228
147HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.67942797

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.15067089
2MP0010094_abnormal_chromosome_stability4.11549054
3MP0003693_abnormal_embryo_hatching3.69579765
4MP0003111_abnormal_nucleus_morphology3.65403378
5MP0003077_abnormal_cell_cycle3.35045892
6* MP0004957_abnormal_blastocyst_morpholog3.00796488
7MP0010352_gastrointestinal_tract_polyps2.99637860
8MP0010307_abnormal_tumor_latency2.72279252
9MP0005451_abnormal_body_composition2.70346849
10MP0008058_abnormal_DNA_repair2.67408141
11MP0008877_abnormal_DNA_methylation2.65599091
12MP0008007_abnormal_cellular_replicative2.53249761
13MP0005076_abnormal_cell_differentiation2.38692148
14MP0001730_embryonic_growth_arrest2.26534776
15MP0003705_abnormal_hypodermis_morpholog2.13431244
16MP0000350_abnormal_cell_proliferation2.08466209
17MP0004233_abnormal_muscle_weight1.99624575
18MP0003123_paternal_imprinting1.92818898
19MP0005380_embryogenesis_phenotype1.91634758
20MP0001672_abnormal_embryogenesis/_devel1.91634758
21MP0004197_abnormal_fetal_growth/weight/1.89227160
22MP0002396_abnormal_hematopoietic_system1.84798830
23MP0004185_abnormal_adipocyte_glucose1.83337076
24MP0003984_embryonic_growth_retardation1.78266526
25MP0002086_abnormal_extraembryonic_tissu1.77013763
26MP0002088_abnormal_embryonic_growth/wei1.75558656
27MP0002084_abnormal_developmental_patter1.74593692
28MP0004808_abnormal_hematopoietic_stem1.73867913
29MP0001697_abnormal_embryo_size1.71397056
30MP0003786_premature_aging1.68530575
31MP0003890_abnormal_embryonic-extraembry1.64899193
32MP0000569_abnormal_digit_pigmentation1.61294247
33* MP0002085_abnormal_embryonic_tissue1.56423733
34MP0002210_abnormal_sex_determination1.52133378
35MP0001929_abnormal_gametogenesis1.51776716
36MP0001293_anophthalmia1.49787923
37MP0003121_genomic_imprinting1.48938823
38* MP0008932_abnormal_embryonic_tissue1.48104227
39MP0005409_darkened_coat_color1.45638700
40* MP0002080_prenatal_lethality1.44002529
41MP0001545_abnormal_hematopoietic_system1.40783130
42MP0005397_hematopoietic_system_phenotyp1.40783130
43MP0009053_abnormal_anal_canal1.40342017
44MP0003221_abnormal_cardiomyocyte_apopto1.38493717
45MP0001145_abnormal_male_reproductive1.33329171
46MP0005410_abnormal_fertilization1.30944307
47MP0003567_abnormal_fetal_cardiomyocyte1.29168536
48MP0000490_abnormal_crypts_of1.25292925
49MP0000537_abnormal_urethra_morphology1.24879924
50MP0003950_abnormal_plasma_membrane1.21486482
51MP0003656_abnormal_erythrocyte_physiolo1.20536053
52MP0004264_abnormal_extraembryonic_tissu1.20193640
53MP0008260_abnormal_autophagy1.19064207
54MP0000313_abnormal_cell_death1.18187143
55MP0000653_abnormal_sex_gland1.17441541
56MP0010678_abnormal_skin_adnexa1.16958865
57MP0003453_abnormal_keratinocyte_physiol1.15840745
58MP0002019_abnormal_tumor_incidence1.12653906
59MP0005666_abnormal_adipose_tissue1.10961597
60MP0003566_abnormal_cell_adhesion1.10101609
61MP0009672_abnormal_birth_weight1.06662314
62MP0001915_intracranial_hemorrhage1.06452925
63MP0002060_abnormal_skin_morphology1.04324918
64MP0000733_abnormal_muscle_development1.04038103
65MP0003698_abnormal_male_reproductive1.03961160
66MP0003937_abnormal_limbs/digits/tail_de1.03477915
67MP0010234_abnormal_vibrissa_follicle1.03270220
68MP0002092_abnormal_eye_morphology1.02356748
69MP0001661_extended_life_span1.01993116
70MP0009703_decreased_birth_body1.01567826
71MP0009278_abnormal_bone_marrow1.00468401
72MP0003828_pulmonary_edema0.98327907
73MP0002877_abnormal_melanocyte_morpholog0.95656120
74MP0000703_abnormal_thymus_morphology0.93206379
75MP0005023_abnormal_wound_healing0.92676283
76MP0002166_altered_tumor_susceptibility0.92470172
77MP0006054_spinal_hemorrhage0.92062074
78MP0002697_abnormal_eye_size0.91581998
79MP0002160_abnormal_reproductive_system0.91181767
80MP0003115_abnormal_respiratory_system0.89177642
81MP0000377_abnormal_hair_follicle0.88899492
82MP0004381_abnormal_hair_follicle0.88463635
83MP0010030_abnormal_orbit_morphology0.88315578
84MP0003119_abnormal_digestive_system0.87470086
85MP0001348_abnormal_lacrimal_gland0.87106783
86MP0005408_hypopigmentation0.86556674
87MP0010630_abnormal_cardiac_muscle0.86002739
88MP0003763_abnormal_thymus_physiology0.85366594
89MP0001119_abnormal_female_reproductive0.84433747
90MP0001216_abnormal_epidermal_layer0.84378434
91MP0002006_tumorigenesis0.83961389
92MP0002925_abnormal_cardiovascular_devel0.83806451
93MP0000627_abnormal_mammary_gland0.83751523
94MP0002009_preneoplasia0.83233323
95MP0002653_abnormal_ependyma_morphology0.81807852
96MP0002796_impaired_skin_barrier0.80919783
97MP0002398_abnormal_bone_marrow0.80842264
98MP0000432_abnormal_head_morphology0.80686961
99MP0003941_abnormal_skin_development0.78187544
100MP0002269_muscular_atrophy0.76511251
101MP0000428_abnormal_craniofacial_morphol0.76162399
102MP0003935_abnormal_craniofacial_develop0.75994256
103MP0001286_abnormal_eye_development0.75943287
104MP0005375_adipose_tissue_phenotype0.75631939
105MP0005621_abnormal_cell_physiology0.75338298
106MP0002161_abnormal_fertility/fecundity0.75058330
107MP0005248_abnormal_Harderian_gland0.74484976
108MP0005501_abnormal_skin_physiology0.73974208
109MP0009115_abnormal_fat_cell0.73044958
110MP0005389_reproductive_system_phenotype0.72819639
111MP0003787_abnormal_imprinting0.72706210
112MP0001851_eye_inflammation0.71884853
113MP0008995_early_reproductive_senescence0.71317443
114MP0000371_diluted_coat_color0.70323889
115MP0003718_maternal_effect0.69825698
116MP0002722_abnormal_immune_system0.68994770
117MP0006138_congestive_heart_failure0.68526811
118MP0000579_abnormal_nail_morphology0.68100450
119MP0002111_abnormal_tail_morphology0.67982452
120MP0003943_abnormal_hepatobiliary_system0.67630893
121MP0005384_cellular_phenotype0.67397302
122MP0003091_abnormal_cell_migration0.66219958
123MP0000689_abnormal_spleen_morphology0.66002215
124MP0005083_abnormal_biliary_tract0.65111160
125MP0001849_ear_inflammation0.64643736
126MP0004947_skin_inflammation0.64567756
127MP0009697_abnormal_copulation0.64138442
128MP0000427_abnormal_hair_cycle0.62489861
129MP0003699_abnormal_female_reproductive0.62356078
130MP0005647_abnormal_sex_gland0.61939305
131MP0002970_abnormal_white_adipose0.61511521
132MP0003300_gastrointestinal_ulcer0.60231946
133MP0000383_abnormal_hair_follicle0.59168241
134MP0005623_abnormal_meninges_morphology0.58824239

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.03335445
2Chromosomal breakage induced by crosslinking agents (HP:0003221)3.64037888
3Subacute progressive viral hepatitis (HP:0006572)3.27808399
4Abnormality of chromosome stability (HP:0003220)3.26172844
5Volvulus (HP:0002580)3.24890652
6Ankyloglossia (HP:0010296)3.22939494
7Ependymoma (HP:0002888)3.10090862
8Selective tooth agenesis (HP:0001592)3.04994780
9Impulsivity (HP:0100710)3.01048915
10Ectopic kidney (HP:0000086)3.00010345
11Medulloblastoma (HP:0002885)2.97389316
12Short 4th metacarpal (HP:0010044)2.82916965
13Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.82916965
14Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.81152800
15Termporal pattern (HP:0011008)2.80273588
16Insidious onset (HP:0003587)2.80273588
17Abnormality of the fingertips (HP:0001211)2.78593690
1811 pairs of ribs (HP:0000878)2.71546231
19Menstrual irregularities (HP:0000858)2.65113671
20Deviation of the thumb (HP:0009603)2.64583204
21Prominent nose (HP:0000448)2.62245595
22Abnormality of oral frenula (HP:0000190)2.62073605
23Rhabdomyosarcoma (HP:0002859)2.61668857
24Heterotopia (HP:0002282)2.59716405
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.59065743
26Relative macrocephaly (HP:0004482)2.57155418
27Birth length less than 3rd percentile (HP:0003561)2.56508417
28Proximal placement of thumb (HP:0009623)2.56503974
29Abnormality of the labia minora (HP:0012880)2.53270425
30Overlapping toe (HP:0001845)2.52968578
31Dysmetric saccades (HP:0000641)2.52223916
32Meckel diverticulum (HP:0002245)2.47238362
33Abnormality of the astrocytes (HP:0100707)2.46889373
34Astrocytoma (HP:0009592)2.46889373
35Increased nuchal translucency (HP:0010880)2.46546510
36Uterine leiomyosarcoma (HP:0002891)2.45343063
37Leiomyosarcoma (HP:0100243)2.45343063
38Long eyelashes (HP:0000527)2.44996037
39Neoplasm of the oral cavity (HP:0100649)2.38176263
40Colon cancer (HP:0003003)2.36707276
41Abnormality of the ileum (HP:0001549)2.33604174
42Myelodysplasia (HP:0002863)2.32887899
43Syringomyelia (HP:0003396)2.31683296
44Spinal cord lesions (HP:0100561)2.31683296
45Biliary tract neoplasm (HP:0100574)2.30871994
46Missing ribs (HP:0000921)2.30025165
47Abnormality of the preputium (HP:0100587)2.29819102
48Transitional cell carcinoma of the bladder (HP:0006740)2.29278296
49Vertebral arch anomaly (HP:0008438)2.28587694
50Thyroid carcinoma (HP:0002890)2.28500386
51Neoplasm of striated muscle (HP:0009728)2.25465777
52Sandal gap (HP:0001852)2.24835581
53Glioma (HP:0009733)2.23198022
54Bladder neoplasm (HP:0009725)2.23064826
55Bladder carcinoma (HP:0002862)2.23064826
56Duodenal stenosis (HP:0100867)2.22195232
57Small intestinal stenosis (HP:0012848)2.22195232
58Resting tremor (HP:0002322)2.17425440
59Curly hair (HP:0002212)2.17281132
60Obsessive-compulsive behavior (HP:0000722)2.14157591
61Asymmetry of the thorax (HP:0001555)2.13627361
62Cystic hygroma (HP:0000476)2.13598213
63Abnormality of the carotid arteries (HP:0005344)2.13152332
64Basal cell carcinoma (HP:0002671)2.09865882
65High pitched voice (HP:0001620)2.09619172
66Dislocated radial head (HP:0003083)2.09149979
67Acute myeloid leukemia (HP:0004808)2.08586521
68Cafe-au-lait spot (HP:0000957)2.08413730
69Sloping forehead (HP:0000340)2.08251809
70Abnormal foot bone ossification (HP:0010675)2.04609328
71Truncal obesity (HP:0001956)2.03369874
72Skull defect (HP:0001362)2.02915365
73Reticulocytopenia (HP:0001896)2.01257892
74Facial hemangioma (HP:0000329)2.00843677
75Malignant gastrointestinal tract tumors (HP:0006749)1.98945208
76Gastrointestinal carcinoma (HP:0002672)1.98945208
77Abnormal spermatogenesis (HP:0008669)1.94226733
78Degeneration of anterior horn cells (HP:0002398)1.93193099
79Abnormality of the anterior horn cell (HP:0006802)1.93193099
80Absent frontal sinuses (HP:0002688)1.92939211
81Abnormality of the 4th metacarpal (HP:0010012)1.92570923
82Osteolytic defects of the hand bones (HP:0009699)1.92347843
83Osteolytic defects of the phalanges of the hand (HP:0009771)1.92347843
84Abnormality of the lower motor neuron (HP:0002366)1.90640864
85Patellar aplasia (HP:0006443)1.89209158
86Flat acetabular roof (HP:0003180)1.88559036
87Abnormality of the duodenum (HP:0002246)1.88230928
88Absent thumb (HP:0009777)1.88139719
89Abnormal number of incisors (HP:0011064)1.86802912
90Short chin (HP:0000331)1.85086593
91Increased mean platelet volume (HP:0011877)1.84831826
92Acanthocytosis (HP:0001927)1.84620969
93Agnosia (HP:0010524)1.84598744
94Progressive external ophthalmoplegia (HP:0000590)1.83331136
95Cutis marmorata (HP:0000965)1.83321226
96Absent radius (HP:0003974)1.83158079
97Supernumerary ribs (HP:0005815)1.82946760
98Cubitus valgus (HP:0002967)1.82716786
99Squamous cell carcinoma (HP:0002860)1.82695242
100Amaurosis fugax (HP:0100576)1.82591105
101Abnormality of chromosome segregation (HP:0002916)1.81985489
102Short thumb (HP:0009778)1.81417231
103Hypopigmentation of the fundus (HP:0007894)1.81225711
104Broad palm (HP:0001169)1.81151713
105Abnormality of the radial head (HP:0003995)1.80560999
106Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.80225803
107Nephroblastoma (Wilms tumor) (HP:0002667)1.79849762
108Aplasia/Hypoplasia of the sternum (HP:0006714)1.78877605
109Supernumerary spleens (HP:0009799)1.77679171
110Neoplasm of the pancreas (HP:0002894)1.77429553
111Deep philtrum (HP:0002002)1.77363739
112Viral hepatitis (HP:0006562)1.76666131
113Low anterior hairline (HP:0000294)1.76161497
114Clubbing of toes (HP:0100760)1.74192221
115Urethral obstruction (HP:0000796)1.73659558
116Short humerus (HP:0005792)1.72936755
117Abnormal auditory evoked potentials (HP:0006958)1.72736383
118Micronodular cirrhosis (HP:0001413)1.72704370
119Abnormal platelet volume (HP:0011876)1.72681378
120Renal cell carcinoma (HP:0005584)1.71586472
121Aplasia/Hypoplasia of the patella (HP:0006498)1.70819308
122Subaortic stenosis (HP:0001682)1.69923948
123Abnormality of the left ventricular outflow tract (HP:0011103)1.69923948
124Upper motor neuron abnormality (HP:0002127)1.69512424
125Narrow palate (HP:0000189)1.68912377
126Atresia of the external auditory canal (HP:0000413)1.67081807
127Renovascular hypertension (HP:0100817)1.66992365
128Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.66119481
129Embryonal renal neoplasm (HP:0011794)1.65941892
130Aplasia/hypoplasia of the humerus (HP:0006507)1.65733719
131Cortical dysplasia (HP:0002539)1.65145226
132Overgrowth (HP:0001548)1.64957364
133Aplasia involving forearm bones (HP:0009822)1.64788599
134Absent forearm bone (HP:0003953)1.64788599
135Orthostatic hypotension (HP:0001278)1.64604550
136Pelvic girdle muscle weakness (HP:0003749)1.64064952
137Supernumerary bones of the axial skeleton (HP:0009144)1.63623642
138Abnormality of the distal phalanx of the thumb (HP:0009617)1.63602785
139Anal stenosis (HP:0002025)1.63411448
140Abnormal biliary tract morphology (HP:0012440)1.62020607
141Freckling (HP:0001480)1.61727143
142Macroorchidism (HP:0000053)1.61466175
143Decreased motor nerve conduction velocity (HP:0003431)1.61358088
144Sparse lateral eyebrow (HP:0005338)1.61051115
145Papillary thyroid carcinoma (HP:0002895)1.60789498
146Abnormality of pyrimidine metabolism (HP:0004353)1.60480193
147Abnormality of DNA repair (HP:0003254)1.59946626
148Neonatal hypoglycemia (HP:0001998)1.59768058
149Breast carcinoma (HP:0003002)1.58939369
150Arteriovenous malformation (HP:0100026)1.58420134
151Cutaneous melanoma (HP:0012056)1.58354799
152Progressive hearing impairment (HP:0001730)1.58199685
153Limited elbow extension (HP:0001377)1.57933040
154Progressive sensorineural hearing impairment (HP:0000408)1.57810485
155Large earlobe (HP:0009748)1.57345336
156Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.57237871
157Capillary hemangiomas (HP:0005306)1.57053043
158Deep palmar crease (HP:0006191)1.55562708
159Underdeveloped nasal alae (HP:0000430)1.55426281
160Coarse hair (HP:0002208)1.55240067
161Advanced eruption of teeth (HP:0006288)1.55001206

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.47412296
2CDC74.34465096
3NEK23.25405622
4WEE12.87785852
5LATS12.64051161
6TTK2.31120105
7EEF2K2.22254177
8SRPK12.19619829
9BRD42.08215972
10MST1R2.07740186
11ACVR1B1.99714261
12STK31.91984499
13ATR1.90295298
14MAP3K21.88135712
15PASK1.70971512
16CDK41.70448907
17AKT31.68909877
18CHEK11.62400225
19PLK11.61794329
20MAP3K101.61188839
21PDK31.60646274
22PDK41.60646274
23BUB11.58722086
24RPS6KB21.57925915
25AURKB1.55974912
26BRSK21.55440256
27PBK1.53030143
28KSR21.52685747
29CHEK21.49882058
30PKN21.47798692
31STK101.45511783
32TSSK61.45327540
33SMG11.45107115
34CDK71.44865261
35CDK61.44788058
36PLK41.44091371
37EPHA21.42958079
38WNK11.42005300
39NEK61.40360390
40PRPF4B1.39505560
41ATM1.38117698
42TLK11.37722137
43EIF2AK11.33743575
44SCYL21.33716603
45NEK11.32967333
46ZAK1.29542789
47MELK1.28573731
48YES11.27648902
49PLK31.24668749
50DYRK31.22995285
51STK41.22632331
52MET1.22544234
53RPS6KA41.21992782
54MKNK11.21127346
55CAMK1D1.20628891
56KSR11.19854273
57MAP3K81.19231141
58PIM11.18664146
59MTOR1.17909357
60MKNK21.16413378
61TGFBR11.11309782
62STK38L1.08835137
63CDK20.98422165
64CDK90.97479486
65ALK0.94217750
66TRPM70.93651737
67MAP3K140.89445253
68SGK30.87369701
69MAP3K60.83475704
70FLT30.82240686
71CDK10.76823190
72PNCK0.75792427
73BMPR20.75077331
74PDK20.75069287
75RAF10.74545659
76TTN0.74539176
77ICK0.74501721
78CHUK0.74441372
79CLK10.73168505
80NLK0.73081975
81FGFR30.71820906
82FRK0.71755874
83TAF10.71351913
84PIK3CG0.71321638
85IRAK20.70686262
86JAK30.68950062
87NUAK10.68586804
88FGFR20.67775389
89STK240.65991641
90RET0.65788010
91CSNK1D0.65753488
92SGK20.63853375
93CAMK1G0.62377755
94MAP3K90.62245919
95FGFR10.62095399
96PTK60.59136308
97PDGFRA0.58597648
98PRKDC0.58257523
99EIF2AK30.58174325
100VRK10.56852201
101MAP4K10.55689875
102STK380.55681101
103PAK20.55574682
104MAP3K10.53637444
105SIK30.53210372
106BRAF0.52515125
107RPS6KB10.52115305
108SIK20.51243299
109IRAK10.50734981
110MAP3K130.50501910
111ERBB30.49900932
112PLK20.49825253
113MARK30.49584830
114BRSK10.48947651
115PAK40.48652875
116AURKA0.48591169
117PTK20.48380860
118RPS6KA50.47916541
119MAP2K30.47797874
120MAPK100.47796370
121CSNK2A20.47060121
122MAPK140.46568787
123PDGFRB0.45456982
124LATS20.45092820
125SIK10.45032298
126FGFR40.44993254
127AKT10.41974034
128CSNK1E0.41497356
129AKT20.41285136
130TRIB30.38966985
131NEK90.37900059
132ERBB40.37678443
133LRRK20.37284474
134* MAPK10.34461229
135GSK3B0.32895176
136RIPK10.32441346
137BMX0.31500792
138EIF2AK20.31016136
139CCNB10.28570636

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.50274543
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.43703190
3RNA transport_Homo sapiens_hsa030133.11614283
4Mismatch repair_Homo sapiens_hsa034303.03311536
5One carbon pool by folate_Homo sapiens_hsa006703.00770699
6Cell cycle_Homo sapiens_hsa041102.91293966
7Fanconi anemia pathway_Homo sapiens_hsa034602.60086159
8Spliceosome_Homo sapiens_hsa030402.59797190
9Homologous recombination_Homo sapiens_hsa034402.35132633
10Systemic lupus erythematosus_Homo sapiens_hsa053222.34254553
11Non-homologous end-joining_Homo sapiens_hsa034502.33448656
12mRNA surveillance pathway_Homo sapiens_hsa030152.24749804
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.16296146
14Nucleotide excision repair_Homo sapiens_hsa034202.09889060
15Base excision repair_Homo sapiens_hsa034102.06261949
16RNA degradation_Homo sapiens_hsa030181.79944711
17p53 signaling pathway_Homo sapiens_hsa041151.79822969
18Basal transcription factors_Homo sapiens_hsa030221.72099842
19Selenocompound metabolism_Homo sapiens_hsa004501.70813429
20Renal cell carcinoma_Homo sapiens_hsa052111.60402350
21Viral carcinogenesis_Homo sapiens_hsa052031.56631088
22Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.55223733
23RNA polymerase_Homo sapiens_hsa030201.47894661
24Lysine degradation_Homo sapiens_hsa003101.47474376
25MicroRNAs in cancer_Homo sapiens_hsa052061.37984743
26Inositol phosphate metabolism_Homo sapiens_hsa005621.37331628
27Glioma_Homo sapiens_hsa052141.37076139
28Small cell lung cancer_Homo sapiens_hsa052221.34773191
29ErbB signaling pathway_Homo sapiens_hsa040121.33763831
30Phosphatidylinositol signaling system_Homo sapiens_hsa040701.32652158
31Pyrimidine metabolism_Homo sapiens_hsa002401.30955660
32Herpes simplex infection_Homo sapiens_hsa051681.29835331
33Antigen processing and presentation_Homo sapiens_hsa046121.21047913
34HTLV-I infection_Homo sapiens_hsa051661.15370695
35AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.14199951
36Prolactin signaling pathway_Homo sapiens_hsa049171.10929558
37Transcriptional misregulation in cancer_Homo sapiens_hsa052021.07382393
38Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.06041802
39Epstein-Barr virus infection_Homo sapiens_hsa051691.04901973
40Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.04516250
41VEGF signaling pathway_Homo sapiens_hsa043700.99366550
42Adherens junction_Homo sapiens_hsa045200.98140763
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.97513978
44Oocyte meiosis_Homo sapiens_hsa041140.94817326
45NF-kappa B signaling pathway_Homo sapiens_hsa040640.92676200
46TGF-beta signaling pathway_Homo sapiens_hsa043500.91844819
47Choline metabolism in cancer_Homo sapiens_hsa052310.90515838
48Neurotrophin signaling pathway_Homo sapiens_hsa047220.90511415
49Chronic myeloid leukemia_Homo sapiens_hsa052200.90266394
50Insulin signaling pathway_Homo sapiens_hsa049100.89886776
51Basal cell carcinoma_Homo sapiens_hsa052170.87107890
52Alcoholism_Homo sapiens_hsa050340.82355091
53Vitamin B6 metabolism_Homo sapiens_hsa007500.81741759
54mTOR signaling pathway_Homo sapiens_hsa041500.80360540
55Notch signaling pathway_Homo sapiens_hsa043300.76853882
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.75267011
57Hippo signaling pathway_Homo sapiens_hsa043900.75239544
58Circadian rhythm_Homo sapiens_hsa047100.74443917
59Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.72547692
60Thyroid cancer_Homo sapiens_hsa052160.72433306
61Pentose phosphate pathway_Homo sapiens_hsa000300.71282939
62Estrogen signaling pathway_Homo sapiens_hsa049150.69907772
63Hepatitis B_Homo sapiens_hsa051610.69827166
64Central carbon metabolism in cancer_Homo sapiens_hsa052300.69579939
65Melanoma_Homo sapiens_hsa052180.69250314
66Biosynthesis of amino acids_Homo sapiens_hsa012300.69174243
67Hepatitis C_Homo sapiens_hsa051600.68637076
68Prostate cancer_Homo sapiens_hsa052150.68455765
69Purine metabolism_Homo sapiens_hsa002300.67109003
70Leukocyte transendothelial migration_Homo sapiens_hsa046700.66194908
71Colorectal cancer_Homo sapiens_hsa052100.64674874
72Measles_Homo sapiens_hsa051620.64602820
73Sphingolipid signaling pathway_Homo sapiens_hsa040710.64067065
74Type II diabetes mellitus_Homo sapiens_hsa049300.63252893
75Platelet activation_Homo sapiens_hsa046110.62795995
76Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62380817
77Ribosome_Homo sapiens_hsa030100.60828381
78Long-term potentiation_Homo sapiens_hsa047200.60669363
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.59391134
80Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58913181
81Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58084012
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.58045513
83Apoptosis_Homo sapiens_hsa042100.57971573
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57012665
85Shigellosis_Homo sapiens_hsa051310.56471968
86Proteoglycans in cancer_Homo sapiens_hsa052050.56388324
87Viral myocarditis_Homo sapiens_hsa054160.55635873
88Dorso-ventral axis formation_Homo sapiens_hsa043200.54444538
89Influenza A_Homo sapiens_hsa051640.53834915
90Pancreatic cancer_Homo sapiens_hsa052120.53771489
91Pathways in cancer_Homo sapiens_hsa052000.52417593
92Fatty acid biosynthesis_Homo sapiens_hsa000610.52049618
93FoxO signaling pathway_Homo sapiens_hsa040680.50312310
94Non-small cell lung cancer_Homo sapiens_hsa052230.50157666
95GnRH signaling pathway_Homo sapiens_hsa049120.50111977
96Acute myeloid leukemia_Homo sapiens_hsa052210.49960601
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.49567593
98Legionellosis_Homo sapiens_hsa051340.49544824
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.49082067
100Toxoplasmosis_Homo sapiens_hsa051450.47602040
101Bladder cancer_Homo sapiens_hsa052190.46737552
102Primary immunodeficiency_Homo sapiens_hsa053400.44144275
103B cell receptor signaling pathway_Homo sapiens_hsa046620.43200803
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43087566
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42956116
106Hedgehog signaling pathway_Homo sapiens_hsa043400.42890605
107Endometrial cancer_Homo sapiens_hsa052130.42193330
108Nitrogen metabolism_Homo sapiens_hsa009100.42135312
109Jak-STAT signaling pathway_Homo sapiens_hsa046300.41847696
110Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40819405
111ECM-receptor interaction_Homo sapiens_hsa045120.38243461
112HIF-1 signaling pathway_Homo sapiens_hsa040660.36997128
113Wnt signaling pathway_Homo sapiens_hsa043100.36270938
114Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36193560
115Glucagon signaling pathway_Homo sapiens_hsa049220.34806133
116T cell receptor signaling pathway_Homo sapiens_hsa046600.34722809
117TNF signaling pathway_Homo sapiens_hsa046680.34530267
118Insulin resistance_Homo sapiens_hsa049310.34432415
119Cyanoamino acid metabolism_Homo sapiens_hsa004600.34344834
120Hematopoietic cell lineage_Homo sapiens_hsa046400.33339680
121AMPK signaling pathway_Homo sapiens_hsa041520.33153430
122Focal adhesion_Homo sapiens_hsa045100.32667322
123Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.32358493
124Longevity regulating pathway - mammal_Homo sapiens_hsa042110.30982686
125Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.29201365
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.28731004
127Intestinal immune network for IgA production_Homo sapiens_hsa046720.27287143

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