AGBL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)8.38358986
2axonemal dynein complex assembly (GO:0070286)6.89830693
3cilium movement (GO:0003341)6.61599629
4epithelial cilium movement (GO:0003351)6.60688412
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.22606934
6acrosome reaction (GO:0007340)5.58226497
7behavioral response to nicotine (GO:0035095)5.52287193
8sperm motility (GO:0030317)5.19664109
9motile cilium assembly (GO:0044458)5.11089003
10fusion of sperm to egg plasma membrane (GO:0007342)5.10304367
11multicellular organism reproduction (GO:0032504)5.01551031
12axoneme assembly (GO:0035082)4.87327538
13response to pheromone (GO:0019236)4.83154219
14protein localization to cilium (GO:0061512)4.77222426
15intraciliary transport (GO:0042073)4.69317706
16acrosome assembly (GO:0001675)4.67018002
17piRNA metabolic process (GO:0034587)4.33631576
18regulation of action potential (GO:0098900)4.07527623
19presynaptic membrane assembly (GO:0097105)4.05377025
20cell wall macromolecule metabolic process (GO:0044036)4.04255362
21cell wall macromolecule catabolic process (GO:0016998)4.04255362
22plasma membrane fusion (GO:0045026)4.03743555
23regulation of cilium movement (GO:0003352)3.91608844
24male meiosis (GO:0007140)3.88994875
25cilium assembly (GO:0042384)3.88710261
26kynurenine metabolic process (GO:0070189)3.88519102
27cilium organization (GO:0044782)3.88207162
28daunorubicin metabolic process (GO:0044597)3.83551770
29polyketide metabolic process (GO:0030638)3.83551770
30doxorubicin metabolic process (GO:0044598)3.83551770
31cellular ketone body metabolic process (GO:0046950)3.82684401
32sperm-egg recognition (GO:0035036)3.80143115
33reproduction (GO:0000003)3.76262640
34centriole replication (GO:0007099)3.73791484
35indole-containing compound catabolic process (GO:0042436)3.72736307
36indolalkylamine catabolic process (GO:0046218)3.72736307
37tryptophan catabolic process (GO:0006569)3.72736307
38single fertilization (GO:0007338)3.70793728
39centriole assembly (GO:0098534)3.68813556
40spinal cord motor neuron differentiation (GO:0021522)3.68408416
41ventricular system development (GO:0021591)3.66737269
42glycerophospholipid catabolic process (GO:0046475)3.61768767
43neuron cell-cell adhesion (GO:0007158)3.57186682
44neuronal action potential (GO:0019228)3.56412943
45spermatid development (GO:0007286)3.54639616
46presynaptic membrane organization (GO:0097090)3.52821919
47regulation of memory T cell differentiation (GO:0043380)3.51792458
48neuronal action potential propagation (GO:0019227)3.51423567
49startle response (GO:0001964)3.44065350
50L-fucose metabolic process (GO:0042354)3.38163045
51L-fucose catabolic process (GO:0042355)3.38163045
52fucose catabolic process (GO:0019317)3.38163045
53nonmotile primary cilium assembly (GO:0035058)3.37781764
54ketone body metabolic process (GO:1902224)3.34900994
55platelet dense granule organization (GO:0060155)3.34496643
56synaptic transmission, cholinergic (GO:0007271)3.32228323
57cilium morphogenesis (GO:0060271)3.31771135
58cell-cell recognition (GO:0009988)3.30520736
59tryptophan metabolic process (GO:0006568)3.29440179
60phosphatidylethanolamine metabolic process (GO:0046337)3.27734100
61establishment of protein localization to Golgi (GO:0072600)3.27313698
62indolalkylamine metabolic process (GO:0006586)3.27237495
63cellular component assembly involved in morphogenesis (GO:0010927)3.26545732
64detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.26458068
65water-soluble vitamin biosynthetic process (GO:0042364)3.25996913
66sperm capacitation (GO:0048240)3.25943116
67synapsis (GO:0007129)3.25065441
68DNA methylation involved in gamete generation (GO:0043046)3.22890335
69negative regulation of synaptic transmission, GABAergic (GO:0032229)3.22149498
70calcium ion-dependent exocytosis (GO:0017156)3.21303837
71seminiferous tubule development (GO:0072520)3.15726310
72binding of sperm to zona pellucida (GO:0007339)3.14540899
73L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.13844731
74amine catabolic process (GO:0009310)3.12467059
75cellular biogenic amine catabolic process (GO:0042402)3.12467059
76male meiosis I (GO:0007141)3.11492750
77gamma-aminobutyric acid transport (GO:0015812)3.10893519
78adaptation of signaling pathway (GO:0023058)3.07982760
79photoreceptor cell maintenance (GO:0045494)3.04757332
80protein-cofactor linkage (GO:0018065)3.00795056
81auditory receptor cell stereocilium organization (GO:0060088)3.00290477
82DNA deamination (GO:0045006)2.99462115
83protein targeting to Golgi (GO:0000042)2.99421940
84regulation of microtubule-based movement (GO:0060632)2.96014730
85microtubule polymerization or depolymerization (GO:0031109)2.95655084
86negative regulation of multicellular organism growth (GO:0040015)2.94960417
87lactate metabolic process (GO:0006089)2.94436586
88rRNA methylation (GO:0031167)2.93916273
89fertilization (GO:0009566)2.91513225
90somite rostral/caudal axis specification (GO:0032525)2.91244195
91sex differentiation (GO:0007548)2.89585429
92left/right axis specification (GO:0070986)2.78556559
93RNA destabilization (GO:0050779)2.78212356
94organic cation transport (GO:0015695)2.76849735
95protein localization to synapse (GO:0035418)2.76592593
96protein localization to Golgi apparatus (GO:0034067)2.75211836
97inner ear receptor stereocilium organization (GO:0060122)2.75081319
98rRNA modification (GO:0000154)2.75007043
99NAD biosynthetic process (GO:0009435)2.74326376
100cyclic nucleotide catabolic process (GO:0009214)2.73496906
101adult walking behavior (GO:0007628)2.73325526
102behavioral response to ethanol (GO:0048149)2.72637690
103L-methionine salvage (GO:0071267)2.70862850
104L-methionine biosynthetic process (GO:0071265)2.70862850
105amino acid salvage (GO:0043102)2.70862850
106protein polyglutamylation (GO:0018095)2.70657347
107somatic diversification of immune receptors via somatic mutation (GO:0002566)2.70253373
108somatic hypermutation of immunoglobulin genes (GO:0016446)2.70253373
109detection of calcium ion (GO:0005513)2.69401259
110gamma-aminobutyric acid signaling pathway (GO:0007214)2.67983225
111central nervous system myelination (GO:0022010)2.67845100
112axon ensheathment in central nervous system (GO:0032291)2.67845100
113regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.67360263
114regulation of pigment cell differentiation (GO:0050932)2.67210546
115eye photoreceptor cell differentiation (GO:0001754)2.66687133
116photoreceptor cell differentiation (GO:0046530)2.66687133
117aminoglycoside antibiotic metabolic process (GO:0030647)2.66208025
118protein K11-linked deubiquitination (GO:0035871)2.65626161
119protein neddylation (GO:0045116)2.64813924
120meiosis I (GO:0007127)2.63476316
121negative regulation of inclusion body assembly (GO:0090084)2.62799951
122cell differentiation in spinal cord (GO:0021515)2.62724648
123reciprocal meiotic recombination (GO:0007131)2.62270133
124reciprocal DNA recombination (GO:0035825)2.62270133
125retinal rod cell development (GO:0046548)2.61895185
126mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.61335843
127mitochondrial respiratory chain complex I assembly (GO:0032981)2.61335843
128NADH dehydrogenase complex assembly (GO:0010257)2.61335843
129spermatogenesis (GO:0007283)2.60760537
130retrograde transport, vesicle recycling within Golgi (GO:0000301)2.60324067
131smoothened signaling pathway (GO:0007224)2.59971064
132male gamete generation (GO:0048232)2.59263594
133negative regulation of cytosolic calcium ion concentration (GO:0051481)2.58084283
134nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.56582889
135microtubule depolymerization (GO:0007019)2.55978369
136regulation of establishment of cell polarity (GO:2000114)2.55631430
137nucleoside diphosphate catabolic process (GO:0009134)2.55079708
138regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.55037729
139phosphorelay signal transduction system (GO:0000160)2.54994761
140preassembly of GPI anchor in ER membrane (GO:0016254)2.54851211
141detection of light stimulus involved in sensory perception (GO:0050962)2.54024362
142detection of light stimulus involved in visual perception (GO:0050908)2.54024362
143postsynaptic membrane organization (GO:0001941)2.54015518
144rRNA catabolic process (GO:0016075)2.53848155
145regulation of somitogenesis (GO:0014807)2.53376519
146G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.53187206
147synaptonemal complex organization (GO:0070193)2.50055583
148mesenchymal cell differentiation involved in kidney development (GO:0072161)2.48614967
149mesenchymal cell differentiation involved in renal system development (GO:2001012)2.48614967
150calcium ion import (GO:0070509)2.46080587
151gamete generation (GO:0007276)2.45826084
152positive regulation of meiosis (GO:0045836)2.44856123
153cerebral cortex radially oriented cell migration (GO:0021799)2.43642000
154microtubule-based movement (GO:0007018)2.41654819
155regulation of male gonad development (GO:2000018)2.41198272
156cell projection assembly (GO:0030031)2.40932790
157negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.40905092
158positive regulation of action potential (GO:0045760)2.40581346
159sensory perception of smell (GO:0007608)2.39804044
160long-chain fatty acid biosynthetic process (GO:0042759)2.39788462
161developmental pigmentation (GO:0048066)2.38192173
162appendage development (GO:0048736)2.38140089
163limb development (GO:0060173)2.38140089
164positive regulation of meiotic cell cycle (GO:0051446)2.37975740
165prostate gland growth (GO:0060736)2.36134348
166gonadal mesoderm development (GO:0007506)2.34784186
167cell differentiation involved in metanephros development (GO:0072202)2.34760510
168cAMP catabolic process (GO:0006198)2.34266745

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.94908153
2GBX2_23144817_ChIP-Seq_PC3_Human3.94074988
3ZNF274_21170338_ChIP-Seq_K562_Hela3.37833134
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.02189579
5ZFP57_27257070_Chip-Seq_ESCs_Mouse2.63030134
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.45202634
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.41745564
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.41297994
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.40536239
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.27336120
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.26440611
12SALL1_21062744_ChIP-ChIP_HESCs_Human2.14153904
13TAF15_26573619_Chip-Seq_HEK293_Human2.11205578
14FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.07358027
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.04713393
16MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.02548148
17SUZ12_27294783_Chip-Seq_NPCs_Mouse1.91686874
18HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.89603878
19CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85908901
20SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.85426089
21BMI1_23680149_ChIP-Seq_NPCS_Mouse1.84828423
22P300_19829295_ChIP-Seq_ESCs_Human1.84530575
23NANOG_18555785_Chip-Seq_ESCs_Mouse1.84006306
24TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.82206968
25VDR_22108803_ChIP-Seq_LS180_Human1.80473570
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.80107507
27FUS_26573619_Chip-Seq_HEK293_Human1.77716561
28EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.76654416
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.75657065
30SMAD4_21799915_ChIP-Seq_A2780_Human1.75413027
31PCGF2_27294783_Chip-Seq_NPCs_Mouse1.75152056
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.74628366
33* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.74149422
34RNF2_27304074_Chip-Seq_NSC_Mouse1.73369459
35PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.72103395
36P53_22387025_ChIP-Seq_ESCs_Mouse1.68969120
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.65715106
38IRF1_19129219_ChIP-ChIP_H3396_Human1.63664940
39EZH2_27294783_Chip-Seq_NPCs_Mouse1.63151837
40CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.61804018
41SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.61537610
42ER_23166858_ChIP-Seq_MCF-7_Human1.61419026
43STAT3_18555785_Chip-Seq_ESCs_Mouse1.60291057
44SUZ12_18555785_Chip-Seq_ESCs_Mouse1.59189373
45E2F1_18555785_Chip-Seq_ESCs_Mouse1.56559244
46BCAT_22108803_ChIP-Seq_LS180_Human1.55842365
47MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.55786720
48CMYC_18555785_Chip-Seq_ESCs_Mouse1.55498858
49JARID2_20064375_ChIP-Seq_MESCs_Mouse1.55148032
50IGF1R_20145208_ChIP-Seq_DFB_Human1.54487003
51EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.53991451
52TAL1_26923725_Chip-Seq_HPCs_Mouse1.52218424
53P300_18555785_Chip-Seq_ESCs_Mouse1.50750307
54BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.49466803
55EZH2_27304074_Chip-Seq_ESCs_Mouse1.49377809
56* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.48942305
57SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.47255944
58* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44396875
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43665692
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.43548287
61SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.43052467
62PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.42085782
63OCT4_18555785_Chip-Seq_ESCs_Mouse1.42023844
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.41708070
65MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.41689705
66RUNX1_27457419_Chip-Seq_LIVER_Mouse1.41404375
67SOX2_18555785_Chip-Seq_ESCs_Mouse1.41105116
68NMYC_18555785_Chip-Seq_ESCs_Mouse1.40194959
69EED_16625203_ChIP-ChIP_MESCs_Mouse1.39763701
70REST_21632747_ChIP-Seq_MESCs_Mouse1.38820328
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38126982
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38126982
73* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.37781034
74ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.36650319
75STAT3_23295773_ChIP-Seq_U87_Human1.36539561
76* KDM2B_26808549_Chip-Seq_REH_Human1.36192754
77SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.35705290
78NR3C1_21868756_ChIP-Seq_MCF10A_Human1.35496401
79TCF4_23295773_ChIP-Seq_U87_Human1.34649835
80OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33910558
81SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.33159231
82KLF4_18555785_Chip-Seq_ESCs_Mouse1.32840501
83* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.32768643
84UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.31764676
85PU1_27457419_Chip-Seq_LIVER_Mouse1.31753212
86ZFX_18555785_Chip-Seq_ESCs_Mouse1.31432067
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30033137
88KLF5_20875108_ChIP-Seq_MESCs_Mouse1.29837857
89CRX_20693478_ChIP-Seq_RETINA_Mouse1.29098501
90EZH2_27294783_Chip-Seq_ESCs_Mouse1.27855859
91CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.26636592
92CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26609217
93EWS_26573619_Chip-Seq_HEK293_Human1.26196687
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26121855
95CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.26121115
96TP53_22573176_ChIP-Seq_HFKS_Human1.24979990
97ESRRB_18555785_Chip-Seq_ESCs_Mouse1.24855517
98KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.24214666
99CTCF_18555785_Chip-Seq_ESCs_Mouse1.23580568
100SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.23514053
101* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23476786
102SMAD1_18555785_Chip-Seq_ESCs_Mouse1.22771152
103TCF4_22108803_ChIP-Seq_LS180_Human1.22572438
104FOXA1_25329375_ChIP-Seq_VCAP_Human1.21994451
105FOXA1_27270436_Chip-Seq_PROSTATE_Human1.21994451
106JARID2_20075857_ChIP-Seq_MESCs_Mouse1.21540164
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20815951
108CBP_20019798_ChIP-Seq_JUKART_Human1.20815951
109SOX2_19829295_ChIP-Seq_ESCs_Human1.20437598
110NANOG_19829295_ChIP-Seq_ESCs_Human1.20437598
111MTF2_20144788_ChIP-Seq_MESCs_Mouse1.20146638
112SMAD4_21741376_ChIP-Seq_EPCs_Human1.19580504
113EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.19552537
114OCT4_21477851_ChIP-Seq_ESCs_Mouse1.19140657
115NCOR_22424771_ChIP-Seq_293T_Human1.18394855
116RNF2_27304074_Chip-Seq_ESCs_Mouse1.17511304
117AR_25329375_ChIP-Seq_VCAP_Human1.16405925
118DROSHA_22980978_ChIP-Seq_HELA_Human1.15477480
119RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15354418
120RUNX2_22187159_ChIP-Seq_PCA_Human1.14459224
121ETV2_25802403_ChIP-Seq_MESCs_Mouse1.14173397
122NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.14047565
123MYC_18940864_ChIP-ChIP_HL60_Human1.13961313
124GABP_17652178_ChIP-ChIP_JURKAT_Human1.13534717
125PRDM14_20953172_ChIP-Seq_ESCs_Human1.13140119
126* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.11456177
127GATA3_21878914_ChIP-Seq_MCF-7_Human1.05938995
128AR_20517297_ChIP-Seq_VCAP_Human1.05244668
129ETV1_20927104_ChIP-Seq_GIST48_Human1.04188970
130FLI1_21867929_ChIP-Seq_TH2_Mouse1.03555070
131AUTS2_25519132_ChIP-Seq_293T-REX_Human1.02780071
132EST1_17652178_ChIP-ChIP_JURKAT_Human1.00416983
133PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99586632
134MYC_19829295_ChIP-Seq_ESCs_Human0.98761434
135AR_21572438_ChIP-Seq_LNCaP_Human0.97150612
136TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95724144
137REST_18959480_ChIP-ChIP_MESCs_Mouse0.95544927
138PHF8_20622853_ChIP-Seq_HELA_Human0.95188554
139* TAF2_19829295_ChIP-Seq_ESCs_Human0.95105277
140CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94682884
141RBPJ_21746931_ChIP-Seq_IB4_Human0.94236597

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization4.83509002
2MP0005646_abnormal_pituitary_gland3.65991245
3MP0001188_hyperpigmentation3.44534636
4MP0003880_abnormal_central_pattern2.76428032
5MP0008877_abnormal_DNA_methylation2.64804545
6MP0005171_absent_coat_pigmentation2.41292848
7MP0001984_abnormal_olfaction2.39545036
8MP0005645_abnormal_hypothalamus_physiol2.35299555
9MP0002876_abnormal_thyroid_physiology2.35155390
10MP0003136_yellow_coat_color2.23782336
11MP0003698_abnormal_male_reproductive2.23373092
12MP0001486_abnormal_startle_reflex2.23050543
13MP0009046_muscle_twitch2.21147369
14MP0003787_abnormal_imprinting2.19079153
15MP0006292_abnormal_olfactory_placode2.18198351
16MP0001986_abnormal_taste_sensitivity2.15125084
17MP0005551_abnormal_eye_electrophysiolog2.12331300
18MP0010386_abnormal_urinary_bladder2.06251850
19MP0009745_abnormal_behavioral_response1.93614620
20MP0009697_abnormal_copulation1.84838033
21MP0001929_abnormal_gametogenesis1.84695744
22MP0002837_dystrophic_cardiac_calcinosis1.83867405
23MP0000566_synostosis1.80508838
24MP0002272_abnormal_nervous_system1.78226992
25MP0004043_abnormal_pH_regulation1.75768033
26MP0001502_abnormal_circadian_rhythm1.74879924
27MP0002653_abnormal_ependyma_morphology1.74548076
28MP0002064_seizures1.73181782
29MP0005423_abnormal_somatic_nervous1.72738762
30MP0000569_abnormal_digit_pigmentation1.69585979
31MP0002572_abnormal_emotion/affect_behav1.63607086
32MP0003635_abnormal_synaptic_transmissio1.61161216
33MP0003878_abnormal_ear_physiology1.58959363
34MP0005377_hearing/vestibular/ear_phenot1.58959363
35MP0003122_maternal_imprinting1.58145079
36MP0005409_darkened_coat_color1.55690773
37MP0005379_endocrine/exocrine_gland_phen1.53827214
38MP0004133_heterotaxia1.53163410
39MP0002234_abnormal_pharynx_morphology1.51896120
40MP0003646_muscle_fatigue1.51406507
41MP0008058_abnormal_DNA_repair1.50959133
42MP0002063_abnormal_learning/memory/cond1.49130494
43MP0003718_maternal_effect1.47096075
44MP0001968_abnormal_touch/_nociception1.46969709
45MP0004742_abnormal_vestibular_system1.46608190
46MP0005253_abnormal_eye_physiology1.45937405
47MP0002102_abnormal_ear_morphology1.45118196
48MP0006276_abnormal_autonomic_nervous1.44386190
49MP0004142_abnormal_muscle_tone1.44335738
50MP0002736_abnormal_nociception_after1.43693337
51MP0002067_abnormal_sensory_capabilities1.43647861
52MP0003011_delayed_dark_adaptation1.43589146
53MP0000631_abnormal_neuroendocrine_gland1.42790311
54MP0002734_abnormal_mechanical_nocicepti1.40878542
55MP0001963_abnormal_hearing_physiology1.37994106
56MP0003121_genomic_imprinting1.36485334
57MP0001529_abnormal_vocalization1.34203535
58MP0004270_analgesia1.33943965
59MP0001501_abnormal_sleep_pattern1.33922080
60MP0000778_abnormal_nervous_system1.33182764
61MP0004145_abnormal_muscle_electrophysio1.32532793
62MP0002735_abnormal_chemical_nociception1.30795616
63MP0003950_abnormal_plasma_membrane1.30659830
64MP0003252_abnormal_bile_duct1.29063822
65MP0002557_abnormal_social/conspecific_i1.28246786
66MP0002638_abnormal_pupillary_reflex1.25910142
67MP0000026_abnormal_inner_ear1.24713211
68MP0002210_abnormal_sex_determination1.23141716
69MP0004859_abnormal_synaptic_plasticity1.20189608
70MP0001440_abnormal_grooming_behavior1.17099119
71MP0005084_abnormal_gallbladder_morpholo1.14863212
72MP0001764_abnormal_homeostasis1.13798912
73MP0002733_abnormal_thermal_nociception1.13448694
74MP0003183_abnormal_peptide_metabolism1.12700091
75MP0003890_abnormal_embryonic-extraembry1.12329028
76MP0001485_abnormal_pinna_reflex1.11130338
77MP0001905_abnormal_dopamine_level1.07491023
78MP0006072_abnormal_retinal_apoptosis1.07221465
79MP0002161_abnormal_fertility/fecundity1.05973244
80MP0005389_reproductive_system_phenotype1.05280869
81MP0002160_abnormal_reproductive_system1.03116797
82MP0003195_calcinosis1.00042153
83MP0006036_abnormal_mitochondrial_physio0.99478578
84MP0004885_abnormal_endolymph0.99339804
85MP0002184_abnormal_innervation0.98826511
86MP0000049_abnormal_middle_ear0.97745407
87MP0008872_abnormal_physiological_respon0.97655610
88MP0002752_abnormal_somatic_nervous0.97372445
89MP0003879_abnormal_hair_cell0.97102411
90MP0003137_abnormal_impulse_conducting0.96876395
91MP0005670_abnormal_white_adipose0.96054224
92MP0004147_increased_porphyrin_level0.95425597
93MP0002882_abnormal_neuron_morphology0.94875451
94MP0002229_neurodegeneration0.94381313
95MP0008260_abnormal_autophagy0.94351319
96MP0008875_abnormal_xenobiotic_pharmacok0.94087717
97MP0009780_abnormal_chondrocyte_physiolo0.93742415
98MP0002163_abnormal_gland_morphology0.92376293
99MP0001177_atelectasis0.92177004
100MP0005391_vision/eye_phenotype0.91864347
101MP0002938_white_spotting0.91759887
102MP0002928_abnormal_bile_duct0.91578364
103MP0000653_abnormal_sex_gland0.89962402
104MP0000372_irregular_coat_pigmentation0.89530772
105MP0002138_abnormal_hepatobiliary_system0.89401976
106MP0002751_abnormal_autonomic_nervous0.89328371
107MP0001145_abnormal_male_reproductive0.88260553
108MP0005647_abnormal_sex_gland0.87883381
109MP0008569_lethality_at_weaning0.86919530
110MP0001293_anophthalmia0.85720121
111MP0000427_abnormal_hair_cycle0.85553649
112MP0000015_abnormal_ear_pigmentation0.85394850
113MP0003119_abnormal_digestive_system0.84876321
114MP0005195_abnormal_posterior_eye0.84870499
115MP0006035_abnormal_mitochondrial_morpho0.84672953
116MP0008995_early_reproductive_senescence0.84105476
117MP0004215_abnormal_myocardial_fiber0.82885995
118MP0001664_abnormal_digestion0.82452573
119MP0001324_abnormal_eye_pigmentation0.80850099
120MP0002277_abnormal_respiratory_mucosa0.80601498
121MP0005499_abnormal_olfactory_system0.80356131
122MP0005394_taste/olfaction_phenotype0.80356131
123MP0000955_abnormal_spinal_cord0.79293294
124MP0002909_abnormal_adrenal_gland0.78818894
125MP0005174_abnormal_tail_pigmentation0.78311767
126MP0000920_abnormal_myelination0.76655066
127MP0003690_abnormal_glial_cell0.76373934
128MP0005623_abnormal_meninges_morphology0.74816417
129MP0001970_abnormal_pain_threshold0.74286595
130MP0008789_abnormal_olfactory_epithelium0.73973500
131MP0001765_abnormal_ion_homeostasis0.73215771
132MP0000678_abnormal_parathyroid_gland0.72286581
133MP0005386_behavior/neurological_phenoty0.70558535
134MP0004924_abnormal_behavior0.70558535

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)8.38460265
2Dynein arm defect of respiratory motile cilia (HP:0012255)7.26469479
3Absent/shortened dynein arms (HP:0200106)7.26469479
4Abnormal respiratory motile cilium physiology (HP:0012261)7.08451806
5Abnormal ciliary motility (HP:0012262)6.86099763
6Abnormal respiratory epithelium morphology (HP:0012253)6.12570104
7Abnormal respiratory motile cilium morphology (HP:0005938)6.12570104
8Rhinitis (HP:0012384)5.50698295
9Pendular nystagmus (HP:0012043)4.20748563
10Medial flaring of the eyebrow (HP:0010747)4.18249501
11Nephronophthisis (HP:0000090)3.84663177
12Tubulointerstitial nephritis (HP:0001970)3.67665910
13Abnormality of midbrain morphology (HP:0002418)3.67122666
14Molar tooth sign on MRI (HP:0002419)3.67122666
15Genetic anticipation (HP:0003743)3.64428523
16Chronic bronchitis (HP:0004469)3.53900909
17Pancreatic fibrosis (HP:0100732)3.52661766
18Progressive cerebellar ataxia (HP:0002073)3.50004032
19Abnormality of the renal medulla (HP:0100957)3.38675050
20True hermaphroditism (HP:0010459)3.37332198
21Gait imbalance (HP:0002141)3.36042248
22Congenital primary aphakia (HP:0007707)3.32626172
23Bronchiectasis (HP:0002110)3.17401732
24Nephrogenic diabetes insipidus (HP:0009806)3.11723874
25Decreased central vision (HP:0007663)3.10195314
26Febrile seizures (HP:0002373)2.90931472
27Chronic hepatic failure (HP:0100626)2.89471722
28Focal seizures (HP:0007359)2.86847854
29Severe visual impairment (HP:0001141)2.79867090
30Bony spicule pigmentary retinopathy (HP:0007737)2.77973201
31Median cleft lip (HP:0000161)2.75582388
32Postaxial foot polydactyly (HP:0001830)2.72629096
33Focal motor seizures (HP:0011153)2.70926556
34Hypothermia (HP:0002045)2.70521864
35Congenital sensorineural hearing impairment (HP:0008527)2.70216019
36Pancreatic cysts (HP:0001737)2.68817809
37Dialeptic seizures (HP:0011146)2.63678256
38Infertility (HP:0000789)2.63123692
39Congenital hepatic fibrosis (HP:0002612)2.61825536
40Genital tract atresia (HP:0001827)2.60753908
41Poor coordination (HP:0002370)2.60255396
42Absence seizures (HP:0002121)2.58676260
43Type II lissencephaly (HP:0007260)2.56977344
44Epileptic encephalopathy (HP:0200134)2.53306692
45Vaginal atresia (HP:0000148)2.47133459
46Abnormality of the labia minora (HP:0012880)2.46820825
47Sclerocornea (HP:0000647)2.44378617
48Aplasia/Hypoplasia of the lens (HP:0008063)2.39223010
49Cystic liver disease (HP:0006706)2.38938357
50Abnormal hair whorl (HP:0010721)2.38050461
51Abnormality of the renal cortex (HP:0011035)2.35860314
52Retinal dysplasia (HP:0007973)2.34780097
53Postaxial hand polydactyly (HP:0001162)2.34245266
54Tubulointerstitial abnormality (HP:0001969)2.30497626
55Male pseudohermaphroditism (HP:0000037)2.29997336
56Anencephaly (HP:0002323)2.27038630
57Hemiparesis (HP:0001269)2.26521809
58Tubular atrophy (HP:0000092)2.23534377
59Hyperventilation (HP:0002883)2.23404107
60Occipital encephalocele (HP:0002085)2.12987717
61Renal cortical cysts (HP:0000803)2.12193811
62Large for gestational age (HP:0001520)2.09729723
63Broad-based gait (HP:0002136)2.09321845
64Chronic sinusitis (HP:0011109)2.08893723
65Congenital stationary night blindness (HP:0007642)2.08716091
66Action tremor (HP:0002345)2.06776704
67Aplasia/Hypoplasia of the tongue (HP:0010295)2.03638825
68Attenuation of retinal blood vessels (HP:0007843)2.03402297
69Recurrent sinusitis (HP:0011108)2.02769008
70Abnormal biliary tract physiology (HP:0012439)2.00145246
71Bile duct proliferation (HP:0001408)2.00145246
72Chorioretinal atrophy (HP:0000533)1.99214641
73Azoospermia (HP:0000027)1.99053184
74Abnormality of alanine metabolism (HP:0010916)1.97832509
75Hyperalaninemia (HP:0003348)1.97832509
76Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.97832509
77Septo-optic dysplasia (HP:0100842)1.96000269
78White forelock (HP:0002211)1.94431952
793-Methylglutaconic aciduria (HP:0003535)1.93072290
80Stage 5 chronic kidney disease (HP:0003774)1.92991952
81Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.91343874
82Optic nerve hypoplasia (HP:0000609)1.91297905
83Hyperglycinemia (HP:0002154)1.91236475
84Furrowed tongue (HP:0000221)1.90855463
85Abnormal spermatogenesis (HP:0008669)1.88939317
86Hepatic necrosis (HP:0002605)1.88879754
87Increased CSF lactate (HP:0002490)1.88653572
88Preaxial hand polydactyly (HP:0001177)1.88039490
89Keratoconus (HP:0000563)1.85182158
90Increased corneal curvature (HP:0100692)1.85182158
91Patchy hypopigmentation of hair (HP:0011365)1.84196242
92Polyuria (HP:0000103)1.83461300
93Abnormal drinking behavior (HP:0030082)1.82995145
94Polydipsia (HP:0001959)1.82995145
95Mitochondrial inheritance (HP:0001427)1.82396794
96Absent speech (HP:0001344)1.81996157
97Astigmatism (HP:0000483)1.81438568
98Bronchitis (HP:0012387)1.81287416
99Nephropathy (HP:0000112)1.80798758
100Lissencephaly (HP:0001339)1.78535666
101Sensory axonal neuropathy (HP:0003390)1.78407528
102Hyperglycinuria (HP:0003108)1.75511497
103Hepatocellular necrosis (HP:0001404)1.75291208
104Concave nail (HP:0001598)1.75258422
105Gaze-evoked nystagmus (HP:0000640)1.74863522
106Cerebellar dysplasia (HP:0007033)1.74633391
107Oculomotor apraxia (HP:0000657)1.73089663
108Aganglionic megacolon (HP:0002251)1.72576401
109Hypomagnesemia (HP:0002917)1.72357167
110Congenital, generalized hypertrichosis (HP:0004540)1.71661298
111Supernumerary spleens (HP:0009799)1.70175365
112Abnormality of molar (HP:0011077)1.69855207
113Abnormality of molar morphology (HP:0011070)1.69855207
114Anomalous pulmonary venous return (HP:0010772)1.69758905
115Oligodactyly (hands) (HP:0001180)1.69164222
116Polyphagia (HP:0002591)1.68798585
117Nasal polyposis (HP:0100582)1.68778113
118Protruding tongue (HP:0010808)1.68442598
119Chromosomal breakage induced by crosslinking agents (HP:0003221)1.68253839
120Abnormal rod and cone electroretinograms (HP:0008323)1.67997417
121Retinitis pigmentosa (HP:0000510)1.66914275
122Generalized aminoaciduria (HP:0002909)1.66559151
123Type 2 muscle fiber atrophy (HP:0003554)1.65745186
124Decreased muscle mass (HP:0003199)1.65487921
125Bell-shaped thorax (HP:0001591)1.65281596
126Dyschromatopsia (HP:0007641)1.65170434
127Constricted visual fields (HP:0001133)1.65148463
128Renal dysplasia (HP:0000110)1.64760327
129Nonprogressive disorder (HP:0003680)1.63908450
130Dandy-Walker malformation (HP:0001305)1.63725280
131Abolished electroretinogram (ERG) (HP:0000550)1.61955505
132Abnormality of macular pigmentation (HP:0008002)1.60652895
133Fibular hypoplasia (HP:0003038)1.59026276
134Bifid tongue (HP:0010297)1.58922747
135Abnormality of incisor morphology (HP:0011063)1.58641742
136Absent rod-and cone-mediated responses on ERG (HP:0007688)1.58571533
137Thyroid-stimulating hormone excess (HP:0002925)1.57576747
138Abnormality of the dental root (HP:0006486)1.57270517
139Taurodontia (HP:0000679)1.57270517
140Abnormality of permanent molar morphology (HP:0011071)1.57270517
141Inability to walk (HP:0002540)1.52931206
142Atonic seizures (HP:0010819)1.52753790
143Specific learning disability (HP:0001328)1.51027876
144Choroideremia (HP:0001139)1.49915178
145Optic disc pallor (HP:0000543)1.49486412

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.17935214
2NEK13.34896573
3TNIK3.27250910
4MAP4K22.40371041
5PDK32.35406840
6PDK42.35406840
7PRPF4B2.30776189
8MAP2K72.25389058
9STK162.22261176
10MAPK151.99488606
11INSRR1.98989046
12NEK61.98930114
13STK391.94076480
14PDK21.86522535
15ZAK1.83937885
16OXSR11.82262898
17NTRK31.76296310
18TLK11.73815911
19ADRBK21.68043384
20EIF2AK31.64911812
21ACVR1B1.60646012
22MUSK1.57333090
23CAMKK21.56405037
24WNK41.53195680
25BMPR21.51879800
26SGK21.43537505
27MAPK131.37265163
28SGK4941.30363371
29SGK2231.30363371
30EPHA41.27499996
31PAK31.26185603
32PTK2B1.21518178
33BRSK21.21372123
34YES11.21149222
35CDK31.19731797
36NUAK11.18649408
37AKT31.16912889
38PLK21.15295561
39GRK11.14197150
40MKNK21.13789549
41CCNB11.13438970
42NEK21.10656338
43WNK31.09321547
44BMPR1B1.08816139
45IRAK11.06453457
46IRAK31.06249011
47STK38L1.03750655
48BUB11.01561041
49EPHA31.00940855
50PINK10.99951335
51PKN10.98196757
52EIF2AK20.93378485
53MAP3K40.93258328
54TXK0.92866785
55CSNK1G10.90948357
56PNCK0.90615684
57LATS10.90241817
58TIE10.88785298
59BCR0.87071361
60PRKCE0.86812043
61TGFBR10.85847009
62SIK30.84775473
63MARK20.84434931
64CSNK1G30.81156722
65NTRK20.81086722
66DAPK20.80871926
67BCKDK0.77533549
68ERBB30.76388974
69CSNK1G20.75641825
70OBSCN0.73232326
71BRD40.72055922
72MARK10.71124703
73PIK3CG0.69986303
74CSNK1A1L0.69815980
75DYRK1A0.68883884
76FGR0.66978806
77PRKCG0.66744312
78CAMK2A0.66280954
79TAOK30.65232725
80TNK20.65023201
81CAMK1G0.64202408
82MAP2K40.63681313
83TRIM280.62486915
84WNK10.61421785
85SGK30.61200520
86MAPK70.60580614
87ADRBK10.60095110
88FRK0.58809865
89PRKG10.57353403
90CAMK1D0.55302668
91VRK10.54286397
92WEE10.54267659
93CAMK10.53649032
94PLK40.53209556
95CDC70.52580460
96PLK30.52561240
97GRK70.52320124
98CDK80.51284543
99CAMK2B0.51182333
100MAPKAPK50.51100451
101MAP3K140.50595295
102CLK10.50470953
103ERBB40.50123072
104KIT0.49727813
105STK30.49054092
106FES0.48472472
107NLK0.48339802
108VRK20.48329780
109TAF10.48287552
110MAP2K60.48037383
111RPS6KA50.46673690
112PRKCI0.46301119
113PHKG20.43462280
114PHKG10.43462280
115PLK10.42948209
116CSNK1A10.42656526
117STK110.42070930
118TTK0.41828977
119GRK50.41716241
120SGK10.41634413
121MAP3K120.41540693
122DYRK30.41539466
123TYRO30.40822744
124CDK190.40728496
125IRAK40.40718850
126TEC0.39635009
127SIK20.39559301
128FGFR20.39099429
129CAMK2D0.37461735
130CDK50.35669193
131MARK30.35612854
132FER0.35352283
133MKNK10.33762301
134STK380.33544512
135PRKACA0.32991605
136CAMK40.32434153
137PRKCQ0.32152744
138PRKCZ0.31817984
139DYRK20.31476877
140CAMKK10.29327107

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.31427811
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.91939565
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.87534515
4Butanoate metabolism_Homo sapiens_hsa006502.74231939
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.70237487
6Olfactory transduction_Homo sapiens_hsa047402.43754194
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.32442394
8Phototransduction_Homo sapiens_hsa047442.31445266
9Morphine addiction_Homo sapiens_hsa050322.28135467
10Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.16601314
11Collecting duct acid secretion_Homo sapiens_hsa049662.14473768
12Taste transduction_Homo sapiens_hsa047422.11073955
13Selenocompound metabolism_Homo sapiens_hsa004502.11053067
14Steroid biosynthesis_Homo sapiens_hsa001002.03029823
15Synaptic vesicle cycle_Homo sapiens_hsa047212.00236665
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.93703497
17RNA polymerase_Homo sapiens_hsa030201.92048516
18GABAergic synapse_Homo sapiens_hsa047271.88984319
19Glutamatergic synapse_Homo sapiens_hsa047241.83190460
20Circadian entrainment_Homo sapiens_hsa047131.77411514
21Amphetamine addiction_Homo sapiens_hsa050311.76242289
22Tryptophan metabolism_Homo sapiens_hsa003801.75066692
23Fatty acid elongation_Homo sapiens_hsa000621.74589241
24Serotonergic synapse_Homo sapiens_hsa047261.74226773
25Protein export_Homo sapiens_hsa030601.72432827
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.71643056
27Insulin secretion_Homo sapiens_hsa049111.70670788
28Ether lipid metabolism_Homo sapiens_hsa005651.67484904
29Nitrogen metabolism_Homo sapiens_hsa009101.65415153
30Sphingolipid metabolism_Homo sapiens_hsa006001.59884203
31Fanconi anemia pathway_Homo sapiens_hsa034601.57560275
32Vitamin B6 metabolism_Homo sapiens_hsa007501.53898022
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.51314259
34Basal transcription factors_Homo sapiens_hsa030221.40303975
35Non-homologous end-joining_Homo sapiens_hsa034501.40198090
36Intestinal immune network for IgA production_Homo sapiens_hsa046721.35751432
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.34381641
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.32398703
39Oxidative phosphorylation_Homo sapiens_hsa001901.29760158
40Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.29645311
41RNA degradation_Homo sapiens_hsa030181.29585823
42Rheumatoid arthritis_Homo sapiens_hsa053231.27189487
43Calcium signaling pathway_Homo sapiens_hsa040201.25676130
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.24345601
45Huntingtons disease_Homo sapiens_hsa050161.24028060
46Caffeine metabolism_Homo sapiens_hsa002321.23795721
47Linoleic acid metabolism_Homo sapiens_hsa005911.22612534
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.19159483
49Asthma_Homo sapiens_hsa053101.19007349
50Salivary secretion_Homo sapiens_hsa049701.18532888
51alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.16240979
52Chemical carcinogenesis_Homo sapiens_hsa052041.15301112
53Vibrio cholerae infection_Homo sapiens_hsa051101.15171302
54Circadian rhythm_Homo sapiens_hsa047101.13692226
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10878519
56Renin secretion_Homo sapiens_hsa049241.08065740
57Arachidonic acid metabolism_Homo sapiens_hsa005901.08048177
58Dopaminergic synapse_Homo sapiens_hsa047281.07182320
59Peroxisome_Homo sapiens_hsa041461.06379934
60Type I diabetes mellitus_Homo sapiens_hsa049401.06208200
61Cocaine addiction_Homo sapiens_hsa050301.05511499
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04322600
63SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03900911
64Ovarian steroidogenesis_Homo sapiens_hsa049131.03551910
65Propanoate metabolism_Homo sapiens_hsa006401.01235883
66Fatty acid degradation_Homo sapiens_hsa000710.99473089
67Homologous recombination_Homo sapiens_hsa034400.98396102
68Cholinergic synapse_Homo sapiens_hsa047250.97020481
69Glycosaminoglycan degradation_Homo sapiens_hsa005310.96414637
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.95159998
71Sulfur metabolism_Homo sapiens_hsa009200.92327877
72Autoimmune thyroid disease_Homo sapiens_hsa053200.92323344
73cAMP signaling pathway_Homo sapiens_hsa040240.90225693
74Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88379847
75ABC transporters_Homo sapiens_hsa020100.87741951
76One carbon pool by folate_Homo sapiens_hsa006700.87107964
77beta-Alanine metabolism_Homo sapiens_hsa004100.86683134
78Fatty acid biosynthesis_Homo sapiens_hsa000610.85457802
79Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.83435422
80Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82087366
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81648409
82Other glycan degradation_Homo sapiens_hsa005110.80880169
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80641003
84Axon guidance_Homo sapiens_hsa043600.79462984
85Pyrimidine metabolism_Homo sapiens_hsa002400.78102161
86Vitamin digestion and absorption_Homo sapiens_hsa049770.78003856
87Pentose and glucuronate interconversions_Homo sapiens_hsa000400.77282948
88Glucagon signaling pathway_Homo sapiens_hsa049220.76845638
89Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76018186
90Fat digestion and absorption_Homo sapiens_hsa049750.75949737
91cGMP-PKG signaling pathway_Homo sapiens_hsa040220.74105179
92Fatty acid metabolism_Homo sapiens_hsa012120.73969440
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.73609887
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.71102176
95Cyanoamino acid metabolism_Homo sapiens_hsa004600.70959146
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.70932199
97Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70730469
98Long-term potentiation_Homo sapiens_hsa047200.70681781
99Alzheimers disease_Homo sapiens_hsa050100.70543433
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.70047137
101Pyruvate metabolism_Homo sapiens_hsa006200.68712026
102Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68564518
103Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67934045
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.65446071
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.65275863
106Gastric acid secretion_Homo sapiens_hsa049710.63771583
107Retinol metabolism_Homo sapiens_hsa008300.62908078
108Allograft rejection_Homo sapiens_hsa053300.61751162
109Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61466608
110Regulation of autophagy_Homo sapiens_hsa041400.60771339
111Long-term depression_Homo sapiens_hsa047300.59496043
112Phagosome_Homo sapiens_hsa041450.59140317
113Base excision repair_Homo sapiens_hsa034100.58910964
114Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57500510
115Cardiac muscle contraction_Homo sapiens_hsa042600.56848619
116Thyroid hormone synthesis_Homo sapiens_hsa049180.55812687
117Glycerolipid metabolism_Homo sapiens_hsa005610.55296705
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.55285620
119Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55211490
120Pancreatic secretion_Homo sapiens_hsa049720.55035244
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54235449
122Systemic lupus erythematosus_Homo sapiens_hsa053220.53665854
123Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50920728
124Inositol phosphate metabolism_Homo sapiens_hsa005620.50710042
125Oxytocin signaling pathway_Homo sapiens_hsa049210.50378618
126Parkinsons disease_Homo sapiens_hsa050120.49546800
127Mineral absorption_Homo sapiens_hsa049780.48085459
128Graft-versus-host disease_Homo sapiens_hsa053320.47866203
129Ras signaling pathway_Homo sapiens_hsa040140.47830740
130Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.47233402
131Dorso-ventral axis formation_Homo sapiens_hsa043200.47185942
132Histidine metabolism_Homo sapiens_hsa003400.46279112
133Purine metabolism_Homo sapiens_hsa002300.45802906
134Proteasome_Homo sapiens_hsa030500.45484484
135Alcoholism_Homo sapiens_hsa050340.45105131
136RNA transport_Homo sapiens_hsa030130.44753520
137Metabolic pathways_Homo sapiens_hsa011000.44277446
138N-Glycan biosynthesis_Homo sapiens_hsa005100.42696444
139Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.42297234
140Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.41905720
141Hedgehog signaling pathway_Homo sapiens_hsa043400.41076375
142Primary immunodeficiency_Homo sapiens_hsa053400.41030086
143Glycerophospholipid metabolism_Homo sapiens_hsa005640.38006396
144Nucleotide excision repair_Homo sapiens_hsa034200.37927601
145Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.37750546
146Wnt signaling pathway_Homo sapiens_hsa043100.36695628

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