ADAT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein prenylation (GO:0018342)6.59171804
2prenylation (GO:0097354)6.59171804
3positive regulation of mitotic sister chromatid separation (GO:1901970)5.77566939
4positive regulation of mitotic metaphase/anaphase transition (GO:0045842)5.77566939
5positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)5.77566939
6maturation of SSU-rRNA (GO:0030490)5.59389210
7ribosomal small subunit biogenesis (GO:0042274)5.54856164
8viral transcription (GO:0019083)5.31422656
9translational termination (GO:0006415)5.18806927
10ribosomal small subunit assembly (GO:0000028)5.15088125
11ribosomal large subunit biogenesis (GO:0042273)4.86262100
12formation of translation preinitiation complex (GO:0001731)4.83659174
13fucose catabolic process (GO:0019317)4.62851777
14L-fucose metabolic process (GO:0042354)4.62851777
15L-fucose catabolic process (GO:0042355)4.62851777
16translational elongation (GO:0006414)4.62480137
17translational initiation (GO:0006413)4.54677147
18ribonucleoprotein complex biogenesis (GO:0022613)4.50194511
19SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.47846565
20cotranslational protein targeting to membrane (GO:0006613)4.41090984
21DNA deamination (GO:0045006)4.38671537
22protein targeting to ER (GO:0045047)4.36816802
23nucleobase biosynthetic process (GO:0046112)4.34884876
24DNA strand elongation involved in DNA replication (GO:0006271)4.22303082
25nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.21082588
26double-strand break repair via nonhomologous end joining (GO:0006303)4.19073951
27non-recombinational repair (GO:0000726)4.19073951
28cellular protein complex disassembly (GO:0043624)4.16273637
29proteasome assembly (GO:0043248)4.15943680
30establishment of protein localization to endoplasmic reticulum (GO:0072599)4.14929737
31purine nucleobase biosynthetic process (GO:0009113)4.13422181
32protein localization to endoplasmic reticulum (GO:0070972)4.13108324
33regulation of sister chromatid cohesion (GO:0007063)4.11440944
34viral life cycle (GO:0019058)4.09125370
35cullin deneddylation (GO:0010388)4.08105368
36ribosome biogenesis (GO:0042254)4.06589678
37ribosome assembly (GO:0042255)4.03373044
38DNA replication checkpoint (GO:0000076)4.01989619
39DNA strand elongation (GO:0022616)4.00651071
40negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.97578512
41mitochondrial RNA metabolic process (GO:0000959)3.94074614
42positive regulation of chromosome segregation (GO:0051984)3.93725763
43telomere maintenance via semi-conservative replication (GO:0032201)3.93071348
44translation (GO:0006412)3.92217853
45pseudouridine synthesis (GO:0001522)3.91376159
46DNA replication initiation (GO:0006270)3.91135942
47rRNA processing (GO:0006364)3.91135569
48spliceosomal snRNP assembly (GO:0000387)3.90163405
49protein deneddylation (GO:0000338)3.88209089
50rRNA modification (GO:0000154)3.85771764
51transcription elongation from RNA polymerase III promoter (GO:0006385)3.84974651
52termination of RNA polymerase III transcription (GO:0006386)3.84974651
53positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.76323772
54negative regulation of T cell receptor signaling pathway (GO:0050860)3.76189576
55negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.74627292
56negative regulation of ligase activity (GO:0051352)3.74627292
57rRNA metabolic process (GO:0016072)3.73819130
58regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.72878720
59anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.69171296
60establishment of integrated proviral latency (GO:0075713)3.68118567
61protein complex disassembly (GO:0043241)3.66272513
62replication fork processing (GO:0031297)3.63623238
63DNA replication-dependent nucleosome assembly (GO:0006335)3.60407263
64DNA replication-dependent nucleosome organization (GO:0034723)3.60407263
65cellular component biogenesis (GO:0044085)3.60265833
66double-strand break repair via homologous recombination (GO:0000724)3.58954855
67DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.58926086
68DNA double-strand break processing (GO:0000729)3.55314450
69recombinational repair (GO:0000725)3.54673979
70signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.53176632
71intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.53176632
72signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.51504239
73signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.51504239
74signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.51504239
75signal transduction involved in DNA integrity checkpoint (GO:0072401)3.49607020
76signal transduction involved in DNA damage checkpoint (GO:0072422)3.49607020
77macromolecular complex disassembly (GO:0032984)3.48957395
78mitotic metaphase plate congression (GO:0007080)3.48194568
79telomere maintenance via recombination (GO:0000722)3.47357371
80mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.46034064
81signal transduction involved in cell cycle checkpoint (GO:0072395)3.45458675
827-methylguanosine mRNA capping (GO:0006370)3.44678622
83CENP-A containing nucleosome assembly (GO:0034080)3.43291645
84chromatin remodeling at centromere (GO:0031055)3.41170526
85negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.40655149
86regulation of cellular amino acid metabolic process (GO:0006521)3.39902146
87negative regulation of Ras GTPase activity (GO:0034261)3.38061227
88protein localization to kinetochore (GO:0034501)3.36261064
89transcription elongation from RNA polymerase I promoter (GO:0006362)3.35556504
907-methylguanosine RNA capping (GO:0009452)3.35484920
91RNA capping (GO:0036260)3.35484920
92deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.34253371
93termination of RNA polymerase I transcription (GO:0006363)3.30700479
94positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.30585519
95folic acid-containing compound biosynthetic process (GO:0009396)3.29190861
96regulation of nuclear cell cycle DNA replication (GO:0033262)3.28937169
97nuclear-transcribed mRNA catabolic process (GO:0000956)3.28490265
98transcription-coupled nucleotide-excision repair (GO:0006283)3.28469481
99L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.28010561
100transcription from RNA polymerase I promoter (GO:0006360)3.27008940
101preassembly of GPI anchor in ER membrane (GO:0016254)3.26942057
102spliceosomal complex assembly (GO:0000245)3.26188167
103mitotic nuclear envelope disassembly (GO:0007077)3.26119123
104RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.25117062
105antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.23855965
106establishment of protein localization to mitochondrial membrane (GO:0090151)3.23606845
107negative regulation of DNA-dependent DNA replication (GO:2000104)3.23551794
108DNA unwinding involved in DNA replication (GO:0006268)3.23085902
109telomere maintenance via telomere lengthening (GO:0010833)3.22957933
110mitotic recombination (GO:0006312)3.22200600
111ATP synthesis coupled proton transport (GO:0015986)3.21728605
112energy coupled proton transport, down electrochemical gradient (GO:0015985)3.21728605
113G1/S transition of mitotic cell cycle (GO:0000082)3.20965692
114cell cycle G1/S phase transition (GO:0044843)3.20965692
115regulation of translation in response to stress (GO:0043555)3.16597619
116positive regulation of ligase activity (GO:0051351)3.15591733
117DNA demethylation (GO:0080111)3.15014898
118positive regulation of histone H3-K4 methylation (GO:0051571)3.13629514
119IMP biosynthetic process (GO:0006188)3.11220884
120regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.09420249
121mRNA catabolic process (GO:0006402)3.07352128
122nucleotide-excision repair, DNA gap filling (GO:0006297)3.07137404
123DNA replication-independent nucleosome organization (GO:0034724)3.06085500
124DNA replication-independent nucleosome assembly (GO:0006336)3.06085500
125RNA methylation (GO:0001510)3.05678503
126regulation of ubiquitin-protein transferase activity (GO:0051438)3.05325449
127histone H3-K9 methylation (GO:0051567)3.04773103
128antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.03324739
129maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.98849025
130intra-S DNA damage checkpoint (GO:0031573)2.91946065
131DNA catabolic process, exonucleolytic (GO:0000738)2.88466411
132vesicle fusion (GO:0006906)2.86062641
133synapsis (GO:0007129)2.82358288
134regulation of T cell receptor signaling pathway (GO:0050856)2.80738646
135protein import into peroxisome matrix (GO:0016558)2.79451458
136centriole replication (GO:0007099)2.77662368
137eosinophil chemotaxis (GO:0048245)2.74616421
138reciprocal DNA recombination (GO:0035825)2.73590210
139reciprocal meiotic recombination (GO:0007131)2.73590210
140somatic hypermutation of immunoglobulin genes (GO:0016446)2.73409459
141somatic diversification of immune receptors via somatic mutation (GO:0002566)2.73409459
142transcription from mitochondrial promoter (GO:0006390)2.73276293
143mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.72361182
144mitochondrial respiratory chain complex I assembly (GO:0032981)2.72361182
145NADH dehydrogenase complex assembly (GO:0010257)2.72361182
146seminiferous tubule development (GO:0072520)2.71330926
147somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.70760686
148isotype switching (GO:0045190)2.70760686
149somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.70760686
150autophagic vacuole fusion (GO:0000046)2.68757771
151rRNA methylation (GO:0031167)2.68176483
152telomere maintenance (GO:0000723)2.67220747
153DNA integration (GO:0015074)2.66458416
154peptidyl-lysine trimethylation (GO:0018023)2.66001315
155double-strand break repair (GO:0006302)2.65019010
156telomere organization (GO:0032200)2.64461193
157detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)2.63870247
158methionine biosynthetic process (GO:0009086)2.61869985
159DNA dealkylation (GO:0035510)2.60979283
160coenzyme A biosynthetic process (GO:0015937)2.60503494
161meiotic chromosome segregation (GO:0045132)2.58972733
162nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.58849863
163nuclear pore complex assembly (GO:0051292)2.58835839
164acrosome assembly (GO:0001675)2.58055099
165iron-sulfur cluster assembly (GO:0016226)2.58049297
166metallo-sulfur cluster assembly (GO:0031163)2.58049297
167exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.55542431
168amino acid activation (GO:0043038)2.55461637
169tRNA aminoacylation (GO:0043039)2.55461637
170branch elongation of an epithelium (GO:0060602)2.54701611
171regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.54502471
172eosinophil migration (GO:0072677)2.54384506
173tRNA aminoacylation for protein translation (GO:0006418)2.54377012
174tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.53705905
175RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.53705905
176* tRNA metabolic process (GO:0006399)2.51867439
177DNA recombination (GO:0006310)2.51589872
178regulation of centriole replication (GO:0046599)2.51537698
179regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.51409401
180nuclear pore organization (GO:0006999)2.51327365
181organ growth (GO:0035265)2.50891180

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.58949152
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.70782026
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.94391981
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.81151548
5GATA1_22025678_ChIP-Seq_K562_Human3.69423548
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.69351976
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.64612909
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.37364919
9MYC_19079543_ChIP-ChIP_MESCs_Mouse3.36438455
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.31263600
11E2F4_17652178_ChIP-ChIP_JURKAT_Human3.13945393
12MYC_18358816_ChIP-ChIP_MESCs_Mouse3.12483593
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.12040879
14MYC_19030024_ChIP-ChIP_MESCs_Mouse3.05381228
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.90433227
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.85097998
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.82969331
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.77250398
19* VDR_22108803_ChIP-Seq_LS180_Human2.74359453
20NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.71191982
21FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.66866539
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.52908642
23* XRN2_22483619_ChIP-Seq_HELA_Human2.51169126
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.48777389
25* VDR_23849224_ChIP-Seq_CD4+_Human2.44658892
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.39662567
27SALL1_21062744_ChIP-ChIP_HESCs_Human2.36751633
28* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.32564838
29FLI1_27457419_Chip-Seq_LIVER_Mouse2.31634649
30E2F1_18555785_ChIP-Seq_MESCs_Mouse2.25652055
31ZNF274_21170338_ChIP-Seq_K562_Hela2.25339473
32CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.15627351
33DCP1A_22483619_ChIP-Seq_HELA_Human2.13362048
34RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.11289545
35ELF1_17652178_ChIP-ChIP_JURKAT_Human2.10651130
36* FOXP3_21729870_ChIP-Seq_TREG_Human2.06455118
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.04630758
38THAP11_20581084_ChIP-Seq_MESCs_Mouse2.03193639
39* TTF2_22483619_ChIP-Seq_HELA_Human2.01445729
40NANOG_18555785_ChIP-Seq_MESCs_Mouse2.01200102
41FUS_26573619_Chip-Seq_HEK293_Human1.98483865
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.97482175
43GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.95573909
44* GABP_19822575_ChIP-Seq_HepG2_Human1.89490885
45YY1_21170310_ChIP-Seq_MESCs_Mouse1.89251181
46CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.89207693
47ELK1_19687146_ChIP-ChIP_HELA_Human1.88612887
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.87044238
49EWS_26573619_Chip-Seq_HEK293_Human1.86347875
50MYCN_18555785_ChIP-Seq_MESCs_Mouse1.76096294
51SRF_21415370_ChIP-Seq_HL-1_Mouse1.75241419
52SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.70357146
53POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.68422352
54PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67178087
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.64263003
56PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.63532911
57POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.63456093
58IRF1_19129219_ChIP-ChIP_H3396_Human1.62636444
59IGF1R_20145208_ChIP-Seq_DFB_Human1.56374206
60AR_21909140_ChIP-Seq_LNCAP_Human1.56331895
61YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56330504
62POU3F2_20337985_ChIP-ChIP_501MEL_Human1.54264446
63FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53251966
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.52337774
65TAF15_26573619_Chip-Seq_HEK293_Human1.51745633
66E2F1_21310950_ChIP-Seq_MCF-7_Human1.49447781
67MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.48410791
68HOXB4_20404135_ChIP-ChIP_EML_Mouse1.47397608
69TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.43110426
70ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39949641
71KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.37684611
72KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.37684611
73KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.37684611
74ELK1_22589737_ChIP-Seq_MCF10A_Human1.36127620
75CIITA_25753668_ChIP-Seq_RAJI_Human1.35704770
76KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.34320843
77STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31134459
78* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.28977392
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.25689796
80ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.25252461
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.24156943
82PCGF2_27294783_Chip-Seq_NPCs_Mouse1.23837858
83KDM5A_27292631_Chip-Seq_BREAST_Human1.22173143
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.19032743
85* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.17640902
86PADI4_21655091_ChIP-ChIP_MCF-7_Human1.17398529
87* NOTCH1_21737748_ChIP-Seq_TLL_Human1.16773350
88CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.16135179
89SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15622595
90BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12670603
91TCF3_18692474_ChIP-Seq_MEFs_Mouse1.12326851
92NFE2_27457419_Chip-Seq_LIVER_Mouse1.12115083
93KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.11575180
94NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.10855518
95IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.10215032
96EZH2_27294783_Chip-Seq_NPCs_Mouse1.09761676
97MYC_18940864_ChIP-ChIP_HL60_Human1.09508057
98KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09467460
99P300_19829295_ChIP-Seq_ESCs_Human1.08803594
100SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08160719
101TP53_22573176_ChIP-Seq_HFKS_Human1.07199162
102TFEB_21752829_ChIP-Seq_HELA_Human1.06258721
103NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.04380183
104NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.04154684
105OCT4_18692474_ChIP-Seq_MEFs_Mouse1.02023194
106EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01017865
107SOX2_18692474_ChIP-Seq_MEFs_Mouse0.99434965
108CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.99308723
109ER_23166858_ChIP-Seq_MCF-7_Human0.98619289
110GATA3_26560356_Chip-Seq_TH1_Human0.97139160
111RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95818880
112SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.95814599
113CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94904634
114GBX2_23144817_ChIP-Seq_PC3_Human0.93469915
115E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92973372
116CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.92658383
117* FOXA1_27270436_Chip-Seq_PROSTATE_Human0.92288493
118* FOXA1_25329375_ChIP-Seq_VCAP_Human0.92288493
119CTBP1_25329375_ChIP-Seq_LNCAP_Human0.91360833
120EGR1_19374776_ChIP-ChIP_THP-1_Human0.90772171
121TP63_19390658_ChIP-ChIP_HaCaT_Human0.90596370
122PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.89866393
123FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.89832704
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89598080
125POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89598080
126MYB_26560356_Chip-Seq_TH2_Human0.89121358
127* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.89081761
128* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.89018185
129DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.88763538
130HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.87899944
131IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87169145
132CBP_20019798_ChIP-Seq_JUKART_Human0.87169145
133BCAT_22108803_ChIP-Seq_LS180_Human0.86767625
134SCL_19346495_ChIP-Seq_HPC-7_Human0.86279126
135* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.86105020
136ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.85318199
137RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.84896029
138SOX2_19829295_ChIP-Seq_ESCs_Human0.84617981
139NANOG_19829295_ChIP-Seq_ESCs_Human0.84617981
140MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.84469976
141GATA3_26560356_Chip-Seq_TH2_Human0.84415061
142UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84377161
143IRF8_22096565_ChIP-ChIP_GC-B_Human0.83258252
144CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.83183631
145SPI1_23547873_ChIP-Seq_NB4_Human0.82655447
146SOX17_20123909_ChIP-Seq_XEN_Mouse0.81529427
147HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.79269629
148NANOG_21062744_ChIP-ChIP_HESCs_Human0.79072579
149* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.77011086
150NANOG_18692474_ChIP-Seq_MEFs_Mouse0.76818650

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.83777937
2MP0004957_abnormal_blastocyst_morpholog4.91677692
3MP0008057_abnormal_DNA_replication4.42416366
4MP0010094_abnormal_chromosome_stability4.32256059
5MP0003111_abnormal_nucleus_morphology4.17988425
6MP0003077_abnormal_cell_cycle4.14326554
7MP0008058_abnormal_DNA_repair3.79368519
8MP0000566_synostosis3.61484805
9MP0008932_abnormal_embryonic_tissue3.18535978
10MP0009379_abnormal_foot_pigmentation3.04872528
11MP0003806_abnormal_nucleotide_metabolis2.96789296
12MP0003303_peritoneal_inflammation2.85480669
13MP0008007_abnormal_cellular_replicative2.85168971
14MP0003786_premature_aging2.54008272
15MP0003123_paternal_imprinting2.37168678
16MP0001730_embryonic_growth_arrest2.22786630
17MP0000350_abnormal_cell_proliferation2.16366863
18MP0000372_irregular_coat_pigmentation2.10870264
19MP0003718_maternal_effect1.98243882
20MP0002396_abnormal_hematopoietic_system1.90332632
21MP0004147_increased_porphyrin_level1.89922170
22MP0002102_abnormal_ear_morphology1.74782023
23MP0003186_abnormal_redox_activity1.73185056
24MP0004133_heterotaxia1.70980435
25MP0006292_abnormal_olfactory_placode1.66669393
26MP0008877_abnormal_DNA_methylation1.66397237
27MP0001697_abnormal_embryo_size1.61947270
28MP0001672_abnormal_embryogenesis/_devel1.61513823
29MP0005380_embryogenesis_phenotype1.61513823
30MP0008995_early_reproductive_senescence1.60625376
31MP0002080_prenatal_lethality1.57841054
32MP0003315_abnormal_perineum_morphology1.57010239
33MP0000313_abnormal_cell_death1.54504080
34MP0005084_abnormal_gallbladder_morpholo1.51887070
35MP0003984_embryonic_growth_retardation1.48150841
36MP0002088_abnormal_embryonic_growth/wei1.44012611
37MP0010352_gastrointestinal_tract_polyps1.43963760
38MP0002837_dystrophic_cardiac_calcinosis1.42428107
39MP0002751_abnormal_autonomic_nervous1.42397451
40MP0009333_abnormal_splenocyte_physiolog1.41317964
41MP0005645_abnormal_hypothalamus_physiol1.39819088
42MP0010307_abnormal_tumor_latency1.39798972
43MP0000383_abnormal_hair_follicle1.37269407
44MP0002085_abnormal_embryonic_tissue1.37000040
45MP0003567_abnormal_fetal_cardiomyocyte1.36635958
46MP0006035_abnormal_mitochondrial_morpho1.34990491
47MP0005397_hematopoietic_system_phenotyp1.34724881
48MP0001545_abnormal_hematopoietic_system1.34724881
49MP0006054_spinal_hemorrhage1.30785887
50MP0003195_calcinosis1.30374805
51MP0000490_abnormal_crypts_of1.29861198
52MP0002210_abnormal_sex_determination1.26770346
53MP0002019_abnormal_tumor_incidence1.25820592
54MP0005646_abnormal_pituitary_gland1.25662404
55MP0006082_CNS_inflammation1.25478683
56MP0001663_abnormal_digestive_system1.23678747
57MP0008872_abnormal_physiological_respon1.23219251
58MP0003787_abnormal_imprinting1.21574531
59MP0000358_abnormal_cell_content/1.21195479
60MP0003941_abnormal_skin_development1.17400373
61MP0005671_abnormal_response_to1.15482236
62MP0001293_anophthalmia1.15158069
63MP0001145_abnormal_male_reproductive1.15024457
64MP0002086_abnormal_extraembryonic_tissu1.14616794
65MP0001835_abnormal_antigen_presentation1.13608071
66MP0005266_abnormal_metabolism1.13413037
67MP0003890_abnormal_embryonic-extraembry1.12459818
68MP0002084_abnormal_developmental_patter1.12449718
69MP0003937_abnormal_limbs/digits/tail_de1.12342012
70MP0004197_abnormal_fetal_growth/weight/1.10905199
71MP0006072_abnormal_retinal_apoptosis1.09388348
72MP0003121_genomic_imprinting1.08453041
73MP0001800_abnormal_humoral_immune1.07592444
74MP0000703_abnormal_thymus_morphology1.06471022
75MP0001727_abnormal_embryo_implantation1.05147792
76MP0006036_abnormal_mitochondrial_physio1.05132861
77MP0005551_abnormal_eye_electrophysiolog1.04592967
78MP0000750_abnormal_muscle_regeneration1.02150512
79MP0002160_abnormal_reproductive_system1.00786907
80MP0005253_abnormal_eye_physiology1.00757114
81MP0009697_abnormal_copulation1.00563261
82MP0001853_heart_inflammation0.99909986
83MP0002163_abnormal_gland_morphology0.99749011
84MP0003646_muscle_fatigue0.98068633
85MP0001929_abnormal_gametogenesis0.97938262
86MP0005174_abnormal_tail_pigmentation0.97556171
87MP0001873_stomach_inflammation0.92656758
88MP0000653_abnormal_sex_gland0.91604578
89MP0002722_abnormal_immune_system0.91519140
90MP0003943_abnormal_hepatobiliary_system0.91033532
91MP0010030_abnormal_orbit_morphology0.90883513
92MP0000858_altered_metastatic_potential0.90846610
93MP0000689_abnormal_spleen_morphology0.89212258
94MP0005389_reproductive_system_phenotype0.89096806
95MP0002398_abnormal_bone_marrow0.88618970
96MP0001986_abnormal_taste_sensitivity0.88138495
97MP0000467_abnormal_esophagus_morphology0.87915498
98MP0002132_abnormal_respiratory_system0.86547334
99MP0001529_abnormal_vocalization0.85806937
100MP0003136_yellow_coat_color0.84901639
101MP0004808_abnormal_hematopoietic_stem0.84845386
102MP0005075_abnormal_melanosome_morpholog0.83209721
103MP0005410_abnormal_fertilization0.82740400
104MP0002938_white_spotting0.81022007
105MP0005384_cellular_phenotype0.80805545
106MP0001664_abnormal_digestion0.80306957
107MP0001188_hyperpigmentation0.78349120
108MP0002429_abnormal_blood_cell0.75259335
109MP0001915_intracranial_hemorrhage0.75169305
110MP0002653_abnormal_ependyma_morphology0.74793180
111MP0005023_abnormal_wound_healing0.74518961
112MP0000569_abnormal_digit_pigmentation0.74472092
113MP0000631_abnormal_neuroendocrine_gland0.74324206
114MP0002127_abnormal_cardiovascular_syste0.74258653
115MP0003221_abnormal_cardiomyocyte_apopto0.74090674
116MP0003828_pulmonary_edema0.73810103
117MP0008873_increased_physiological_sensi0.73080835
118MP0002420_abnormal_adaptive_immunity0.73018601
119MP0002405_respiratory_system_inflammati0.72660268
120MP0001764_abnormal_homeostasis0.71040152
121MP0001819_abnormal_immune_cell0.70859570
122MP0002452_abnormal_antigen_presenting0.70718236
123MP0002736_abnormal_nociception_after0.70706869
124MP0002138_abnormal_hepatobiliary_system0.70085657
125MP0005381_digestive/alimentary_phenotyp0.69663580
126MP0000015_abnormal_ear_pigmentation0.69599155
127MP0002111_abnormal_tail_morphology0.69526342
128MP0001661_extended_life_span0.69065543
129MP0006276_abnormal_autonomic_nervous0.68637255
130MP0001919_abnormal_reproductive_system0.65919312
131MP0003698_abnormal_male_reproductive0.64672725
132MP0005376_homeostasis/metabolism_phenot0.63858371
133MP0005621_abnormal_cell_physiology0.62567627
134MP0002277_abnormal_respiratory_mucosa0.61841466
135MP0001119_abnormal_female_reproductive0.61701420
136MP0001286_abnormal_eye_development0.61196380
137MP0003763_abnormal_thymus_physiology0.60898495
138MP0003448_altered_tumor_morphology0.57997113
139MP0000716_abnormal_immune_system0.55568824
140MP0000049_abnormal_middle_ear0.53393864
141MP0003119_abnormal_digestive_system0.52830259
142MP0004084_abnormal_cardiac_muscle0.50201817
143MP0003938_abnormal_ear_development0.49091480
144MP0005409_darkened_coat_color0.48505090
145MP0002095_abnormal_skin_pigmentation0.48017512
146MP0000516_abnormal_urinary_system0.47880411

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.60431308
2Abnormal number of erythroid precursors (HP:0012131)4.98543019
3Reticulocytopenia (HP:0001896)4.90536343
4Breast hypoplasia (HP:0003187)4.39910926
5Birth length less than 3rd percentile (HP:0003561)4.38155482
6Acute lymphatic leukemia (HP:0006721)4.26697258
7Macrocytic anemia (HP:0001972)3.91821539
8Agnosia (HP:0010524)3.83669027
9Cerebral hypomyelination (HP:0006808)3.53078362
10Acute necrotizing encephalopathy (HP:0006965)3.50101789
11Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.43593836
12Carpal bone hypoplasia (HP:0001498)3.42475058
13Stenosis of the external auditory canal (HP:0000402)3.35204138
14Rough bone trabeculation (HP:0100670)3.33157968
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.26723381
16Mitochondrial inheritance (HP:0001427)3.26634454
17Oral leukoplakia (HP:0002745)3.19188671
18Pallor (HP:0000980)3.18268281
19Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.10027854
20Abnormal mitochondria in muscle tissue (HP:0008316)3.04058579
21Increased CSF lactate (HP:0002490)2.96251230
22Increased hepatocellular lipid droplets (HP:0006565)2.93222990
23Large for gestational age (HP:0001520)2.88323138
24Clubbing of toes (HP:0100760)2.87289187
25Aplastic anemia (HP:0001915)2.87177815
26Hepatocellular necrosis (HP:0001404)2.86964874
27Aplasia/Hypoplasia of the sacrum (HP:0008517)2.78923818
28Progressive macrocephaly (HP:0004481)2.76369840
29Panhypogammaglobulinemia (HP:0003139)2.75893799
30Selective tooth agenesis (HP:0001592)2.73689062
31Multiple enchondromatosis (HP:0005701)2.72725255
32Abnormality of the anterior horn cell (HP:0006802)2.72699169
33Degeneration of anterior horn cells (HP:0002398)2.72699169
34Patellar aplasia (HP:0006443)2.72597245
35Increased serum pyruvate (HP:0003542)2.66250474
36Abnormality of glycolysis (HP:0004366)2.66250474
37Pancreatic cysts (HP:0001737)2.65607487
38Acute encephalopathy (HP:0006846)2.63402935
39Decreased activity of mitochondrial respiratory chain (HP:0008972)2.63083037
40Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.63083037
41Increased serum lactate (HP:0002151)2.56796500
42Secondary amenorrhea (HP:0000869)2.54047151
43Aplasia/Hypoplasia of the patella (HP:0006498)2.51757148
44Colon cancer (HP:0003003)2.51370268
45Absent radius (HP:0003974)2.49992807
46Premature ovarian failure (HP:0008209)2.48247561
47Absent thumb (HP:0009777)2.47681187
48Lipid accumulation in hepatocytes (HP:0006561)2.47494920
49Premature graying of hair (HP:0002216)2.46250843
503-Methylglutaconic aciduria (HP:0003535)2.43718815
51Volvulus (HP:0002580)2.43149337
52Meckel diverticulum (HP:0002245)2.43088844
53Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.41146233
54Brushfield spots (HP:0001088)2.39871806
55Molar tooth sign on MRI (HP:0002419)2.39518335
56Abnormality of midbrain morphology (HP:0002418)2.39518335
57Trismus (HP:0000211)2.34701509
58Abnormal trabecular bone morphology (HP:0100671)2.34576108
59Hepatic necrosis (HP:0002605)2.33637924
60Ependymoma (HP:0002888)2.31605830
61Exertional dyspnea (HP:0002875)2.31282107
62Absent forearm bone (HP:0003953)2.30954691
63Aplasia involving forearm bones (HP:0009822)2.30954691
64Cellular immunodeficiency (HP:0005374)2.30443190
65Type I transferrin isoform profile (HP:0003642)2.30317432
66Renal Fanconi syndrome (HP:0001994)2.29615086
67Hypoplastic pelvis (HP:0008839)2.29551638
68Abnormality of the ileum (HP:0001549)2.28927697
69Chromsome breakage (HP:0040012)2.28884446
70Pancreatic fibrosis (HP:0100732)2.27716894
71Duplicated collecting system (HP:0000081)2.25124072
72Abnormality of the preputium (HP:0100587)2.24775738
73Exercise intolerance (HP:0003546)2.23050883
74Medulloblastoma (HP:0002885)2.23006328
75Congenital stationary night blindness (HP:0007642)2.22887732
76Bone marrow hypocellularity (HP:0005528)2.22107011
77Horseshoe kidney (HP:0000085)2.20929118
78Neoplasm of the pancreas (HP:0002894)2.20496755
79True hermaphroditism (HP:0010459)2.20178829
80Abnormality of the labia minora (HP:0012880)2.19843084
81Long foot (HP:0001833)2.19410732
82Chromosomal breakage induced by crosslinking agents (HP:0003221)2.17633970
83Progressive muscle weakness (HP:0003323)2.17085484
84Metaphyseal dysplasia (HP:0100255)2.16926561
85Abnormality of chromosome stability (HP:0003220)2.15662511
86Severe combined immunodeficiency (HP:0004430)2.15556193
87Cleft eyelid (HP:0000625)2.15488738
88Abnormality of the renal cortex (HP:0011035)2.13308554
89Abnormality of the renal collecting system (HP:0004742)2.11796695
90Pancreatic islet-cell hyperplasia (HP:0004510)2.11135719
91Abnormal number of incisors (HP:0011064)2.10927652
92Progressive external ophthalmoplegia (HP:0000590)2.10294173
93Renal cortical cysts (HP:0000803)2.08011233
94Dry hair (HP:0011359)2.06524050
95Methylmalonic acidemia (HP:0002912)2.06141600
9611 pairs of ribs (HP:0000878)2.05938002
97Atrophy/Degeneration involving motor neurons (HP:0007373)2.03537683
98Personality changes (HP:0000751)2.03418332
99Supernumerary spleens (HP:0009799)2.02805401
100Ureteral duplication (HP:0000073)2.01301952
101Myelodysplasia (HP:0002863)2.01166599
102Abnormal lung lobation (HP:0002101)2.00817558
103Respiratory difficulties (HP:0002880)1.99242712
104Lactic acidosis (HP:0003128)1.97985214
105IgG deficiency (HP:0004315)1.97058739
106Glossoptosis (HP:0000162)1.96385270
107Hypoplastic iliac wings (HP:0002866)1.95557411
108Duodenal stenosis (HP:0100867)1.95500916
109Small intestinal stenosis (HP:0012848)1.95500916
110Triphalangeal thumb (HP:0001199)1.94643434
111Microretrognathia (HP:0000308)1.94619632
112Abnormality of the pons (HP:0007361)1.94558027
113IgM deficiency (HP:0002850)1.93798049
114Abnormality of DNA repair (HP:0003254)1.93167699
115Cerebral edema (HP:0002181)1.92515628
116Abnormality of fatty-acid metabolism (HP:0004359)1.92373365
117Microvesicular hepatic steatosis (HP:0001414)1.91928086
118Nephronophthisis (HP:0000090)1.91892490
119Impulsivity (HP:0100710)1.91824143
120Emotional lability (HP:0000712)1.91526234
121Abnormal delayed hypersensitivity skin test (HP:0002963)1.91224326
122Aplasia/hypoplasia of the humerus (HP:0006507)1.91197043
123Aplasia/Hypoplasia of the uvula (HP:0010293)1.89929586
124Respiratory failure (HP:0002878)1.89598447
125Atresia of the external auditory canal (HP:0000413)1.89231105
126Pancytopenia (HP:0001876)1.87682808
127Attenuation of retinal blood vessels (HP:0007843)1.87170483
128Broad-based gait (HP:0002136)1.86939071
129Medial flaring of the eyebrow (HP:0010747)1.86464844
130Abnormality of B cell number (HP:0010975)1.86456078
131Abnormality of methionine metabolism (HP:0010901)1.85870935
132Tongue fasciculations (HP:0001308)1.84232778
133Postnatal microcephaly (HP:0005484)1.84096791
134Muscle fiber atrophy (HP:0100295)1.83954872
135Hypoplasia of the pons (HP:0012110)1.83615721
136Type II lissencephaly (HP:0007260)1.83442788
137Intestinal atresia (HP:0011100)1.83274470
138Sloping forehead (HP:0000340)1.83189239
139Supernumerary bones of the axial skeleton (HP:0009144)1.82486672
140Hyperglycinemia (HP:0002154)1.82358593
141Methylmalonic aciduria (HP:0012120)1.82353673
142Abnormality of aspartate family amino acid metabolism (HP:0010899)1.81820478
143Abnormality of the duodenum (HP:0002246)1.81703027
144Adactyly (HP:0009776)1.79562065
145Stomatitis (HP:0010280)1.78501303
146Combined immunodeficiency (HP:0005387)1.77640990
147Ureteral stenosis (HP:0000071)1.77611420
148Abnormality of the prostate (HP:0008775)1.77419806
149Abnormality of the renal medulla (HP:0100957)1.76128277
150Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.74735933
151Abnormality of alanine metabolism (HP:0010916)1.74735933
152Hyperalaninemia (HP:0003348)1.74735933
153Abolished electroretinogram (ERG) (HP:0000550)1.74503774
154Ectopic kidney (HP:0000086)1.74050049
155B lymphocytopenia (HP:0010976)1.73666922
156Autoimmune hemolytic anemia (HP:0001890)1.73111360
157Abnormality of homocysteine metabolism (HP:0010919)1.72861467
158Homocystinuria (HP:0002156)1.72861467
159Abnormality of T cell physiology (HP:0011840)1.69145752
160Abnormality of the heme biosynthetic pathway (HP:0010472)1.68678756
161Progressive inability to walk (HP:0002505)1.67274551
162Ureteral obstruction (HP:0006000)1.64743220
163Female pseudohermaphroditism (HP:0010458)1.64228747
164Severe muscular hypotonia (HP:0006829)1.63538060
165Abnormality of serum amino acid levels (HP:0003112)1.63183840
166Absent rod-and cone-mediated responses on ERG (HP:0007688)1.62733326
167Decreased electroretinogram (ERG) amplitude (HP:0000654)1.61874161
168Abnormal glycosylation (HP:0012345)1.61799480
169Abnormal protein N-linked glycosylation (HP:0012347)1.61799480

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.04150044
2WEE14.24516638
3NME23.52929539
4EIF2AK13.01896006
5EIF2AK32.86633244
6CDC72.81179735
7STK162.74707003
8TESK22.62786878
9FRK2.59874505
10VRK12.35734184
11SRPK12.28940310
12TSSK62.27179435
13MAP2K32.24802758
14PLK42.24304870
15NEK12.19568560
16NUAK12.19145508
17TAOK12.09189226
18TTK2.04032863
19PIM21.92862167
20PLK11.88035471
21TLK11.87031139
22PLK31.78980479
23PNCK1.61689044
24RPS6KB21.59655301
25TAOK31.59562607
26NME11.58205914
27BMPR1B1.57238402
28EPHA21.53286667
29MAP4K21.52349798
30BRSK21.51285977
31TESK11.50178707
32NEK21.48089024
33MST41.43923605
34AKT31.43748266
35TXK1.43232550
36AURKB1.41933252
37TNIK1.37653617
38ZAK1.36866151
39MAP3K31.34950947
40CDK71.33588617
41MAP3K81.31637843
42MKNK11.27842548
43AURKA1.27292469
44VRK21.26402712
45ATR1.26246094
46ACVR1B1.23705250
47DYRK31.23244015
48STK101.22421423
49PASK1.14375862
50WNK31.13813087
51PAK41.11010023
52FLT31.09653958
53CHEK21.08225367
54ADRBK21.06646484
55DYRK1A1.05757650
56TAF11.04951191
57GRK61.03863960
58CCNB11.01710349
59PBK1.01214459
60GRK10.96197218
61ITK0.95489456
62TRIM280.94495428
63CHEK10.91763393
64BRSK10.86985600
65CSNK2A20.86530607
66PDK30.80111480
67PDK40.80111480
68CSNK2A10.79354232
69BRAF0.78730931
70KDR0.78467111
71WNK40.77476753
72MKNK20.76191440
73PIM10.74160601
74MAP3K110.73626418
75LRRK20.72779355
76CDK40.72560245
77PAK10.72474840
78PDK20.72000801
79TGFBR10.71129806
80MAP3K50.69019527
81BCKDK0.67917939
82EIF2AK20.67709883
83RPS6KA40.66704729
84NLK0.66343097
85PRKCQ0.65586734
86DYRK20.65270995
87KIT0.65002251
88BTK0.64792118
89ATM0.62154958
90CDK20.61863145
91TAOK20.60681494
92MAP4K10.59606358
93STK30.59366834
94INSRR0.58688212
95STK40.57915676
96IRAK30.54745283
97PLK20.54658127
98ALK0.53751335
99IKBKB0.52816837
100TIE10.52156884
101PRKCI0.50972421
102MAPK130.50682408
103LIMK10.50088727
104CDK10.47975092
105CLK10.47957940
106DAPK10.47099432
107MAP3K120.46915495
108GRK50.46686079
109STK390.44940383
110RPS6KA50.44579201
111MAPKAPK50.43837024
112RPS6KL10.43665108
113RPS6KC10.43665108
114ABL20.42724459
115ILK0.42456764
116MAP3K40.40850393
117ARAF0.39352033
118CDK11A0.38872810
119SYK0.38553777
120RPS6KA60.37644462
121PINK10.36446917
122ERBB30.36181696
123BRD40.35839091
124OXSR10.35826795
125ZAP700.35791708
126SCYL20.35490607
127CDK140.35263688
128CDK150.34807067
129MARK30.34192680
130CDK80.34064486
131CDK180.33869422
132DAPK30.33725185
133CSNK1E0.33555516
134STK38L0.33096866
135TEC0.32920979
136IGF1R0.32414630
137ADRBK10.31731469
138CSNK1A10.31617993
139JAK30.31417096
140LYN0.30735985
141LCK0.30557861
142BMPR20.29551551
143CSNK1G10.29211409
144LATS10.28783618
145IRAK40.28466329
146IRAK10.26091349

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.11828241
2Proteasome_Homo sapiens_hsa030504.66554309
3DNA replication_Homo sapiens_hsa030304.19180431
4RNA polymerase_Homo sapiens_hsa030203.95047073
5Mismatch repair_Homo sapiens_hsa034303.72911529
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.62213978
7Spliceosome_Homo sapiens_hsa030403.22382494
8RNA transport_Homo sapiens_hsa030132.86520607
9Pyrimidine metabolism_Homo sapiens_hsa002402.77210619
10Homologous recombination_Homo sapiens_hsa034402.72519237
11Nucleotide excision repair_Homo sapiens_hsa034202.57732561
12One carbon pool by folate_Homo sapiens_hsa006702.36763864
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.28343398
14Base excision repair_Homo sapiens_hsa034102.26048149
15Oxidative phosphorylation_Homo sapiens_hsa001902.22830910
16Parkinsons disease_Homo sapiens_hsa050122.06021345
17Propanoate metabolism_Homo sapiens_hsa006402.05184411
18Fanconi anemia pathway_Homo sapiens_hsa034602.01069713
19Basal transcription factors_Homo sapiens_hsa030222.00018657
20Cell cycle_Homo sapiens_hsa041101.89697279
21Non-homologous end-joining_Homo sapiens_hsa034501.84390556
22Huntingtons disease_Homo sapiens_hsa050161.80062770
23Butanoate metabolism_Homo sapiens_hsa006501.73708173
24RNA degradation_Homo sapiens_hsa030181.71214992
25Protein export_Homo sapiens_hsa030601.55446144
26Purine metabolism_Homo sapiens_hsa002301.50831619
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.50123102
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.45323255
29Nitrogen metabolism_Homo sapiens_hsa009101.37159893
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.36726156
31Epstein-Barr virus infection_Homo sapiens_hsa051691.34846655
32Alzheimers disease_Homo sapiens_hsa050101.29186083
33Fatty acid elongation_Homo sapiens_hsa000621.26076439
34Lysine degradation_Homo sapiens_hsa003101.22495968
35mRNA surveillance pathway_Homo sapiens_hsa030151.20346999
36Phototransduction_Homo sapiens_hsa047441.17246498
37Taste transduction_Homo sapiens_hsa047421.15633431
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15462575
39p53 signaling pathway_Homo sapiens_hsa041151.13526352
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.11561236
41Tryptophan metabolism_Homo sapiens_hsa003801.06483437
42Maturity onset diabetes of the young_Homo sapiens_hsa049501.04050159
43Cysteine and methionine metabolism_Homo sapiens_hsa002700.97556156
44Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.97012688
45Folate biosynthesis_Homo sapiens_hsa007900.94794919
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.93790497
47Intestinal immune network for IgA production_Homo sapiens_hsa046720.89463877
48Biosynthesis of amino acids_Homo sapiens_hsa012300.87692455
49Olfactory transduction_Homo sapiens_hsa047400.86032036
50Glycerolipid metabolism_Homo sapiens_hsa005610.84665119
51Glutathione metabolism_Homo sapiens_hsa004800.83895396
52Peroxisome_Homo sapiens_hsa041460.81393542
53Allograft rejection_Homo sapiens_hsa053300.78875857
54Autoimmune thyroid disease_Homo sapiens_hsa053200.77500138
55Systemic lupus erythematosus_Homo sapiens_hsa053220.76499022
56Oocyte meiosis_Homo sapiens_hsa041140.75729704
57Cyanoamino acid metabolism_Homo sapiens_hsa004600.75611171
58Type I diabetes mellitus_Homo sapiens_hsa049400.73738217
59Antigen processing and presentation_Homo sapiens_hsa046120.73645010
60Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.69855772
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.69331928
62Cardiac muscle contraction_Homo sapiens_hsa042600.65760341
63Fatty acid metabolism_Homo sapiens_hsa012120.65217510
64Drug metabolism - other enzymes_Homo sapiens_hsa009830.64470133
65Fructose and mannose metabolism_Homo sapiens_hsa000510.64145811
66alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.63445603
67Pentose phosphate pathway_Homo sapiens_hsa000300.63342098
68Viral carcinogenesis_Homo sapiens_hsa052030.62923144
69Ether lipid metabolism_Homo sapiens_hsa005650.62486516
70beta-Alanine metabolism_Homo sapiens_hsa004100.61304717
71Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61194523
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.60490033
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60157640
74Vitamin B6 metabolism_Homo sapiens_hsa007500.59533483
75Fatty acid degradation_Homo sapiens_hsa000710.57655612
76Herpes simplex infection_Homo sapiens_hsa051680.56371269
77Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.54379154
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.54341088
79Carbon metabolism_Homo sapiens_hsa012000.52539151
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52452332
81Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.50797333
82Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50236611
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49346673
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48189328
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48059339
86Retinol metabolism_Homo sapiens_hsa008300.47456929
87Legionellosis_Homo sapiens_hsa051340.45399788
88Metabolic pathways_Homo sapiens_hsa011000.45349413
89Caffeine metabolism_Homo sapiens_hsa002320.45008691
90Sulfur relay system_Homo sapiens_hsa041220.42762836
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41900616
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.41664965
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.41181588
94HTLV-I infection_Homo sapiens_hsa051660.41106570
95Primary immunodeficiency_Homo sapiens_hsa053400.40950734
96Steroid biosynthesis_Homo sapiens_hsa001000.39343434
97Glycerophospholipid metabolism_Homo sapiens_hsa005640.37606061
98Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.36014186
99Vitamin digestion and absorption_Homo sapiens_hsa049770.34604691
100Arachidonic acid metabolism_Homo sapiens_hsa005900.32491680
101Chemical carcinogenesis_Homo sapiens_hsa052040.31803811
102Thyroid cancer_Homo sapiens_hsa052160.30174926
103Selenocompound metabolism_Homo sapiens_hsa004500.29726987
104Fat digestion and absorption_Homo sapiens_hsa049750.29614096
105Primary bile acid biosynthesis_Homo sapiens_hsa001200.28030907
106Shigellosis_Homo sapiens_hsa051310.26649974
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.26452368
108Sulfur metabolism_Homo sapiens_hsa009200.26064680
109Graft-versus-host disease_Homo sapiens_hsa053320.25016541
110Jak-STAT signaling pathway_Homo sapiens_hsa046300.24581887
111Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24478974
112Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.24386026
113Galactose metabolism_Homo sapiens_hsa000520.24226417
114Regulation of autophagy_Homo sapiens_hsa041400.23231012
115Alcoholism_Homo sapiens_hsa050340.21738990
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.21088120
117NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20906079
118Apoptosis_Homo sapiens_hsa042100.20737879
119Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.19465079
120Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18195001
121SNARE interactions in vesicular transport_Homo sapiens_hsa041300.16440163
122Small cell lung cancer_Homo sapiens_hsa052220.16118453
123Pyruvate metabolism_Homo sapiens_hsa006200.15678174
124N-Glycan biosynthesis_Homo sapiens_hsa005100.13654526
125HIF-1 signaling pathway_Homo sapiens_hsa040660.13237839
126NF-kappa B signaling pathway_Homo sapiens_hsa040640.11638490
127Hematopoietic cell lineage_Homo sapiens_hsa046400.09997967
128Collecting duct acid secretion_Homo sapiens_hsa049660.08932159
129Bladder cancer_Homo sapiens_hsa052190.08125884
130Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.07706469
131Arginine and proline metabolism_Homo sapiens_hsa003300.07299139
132Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.06949662
133Linoleic acid metabolism_Homo sapiens_hsa005910.05744836
134Hippo signaling pathway_Homo sapiens_hsa043900.05448994
135MicroRNAs in cancer_Homo sapiens_hsa052060.05024385
136Renin-angiotensin system_Homo sapiens_hsa046140.05019407
137Asthma_Homo sapiens_hsa053100.04591656
138Measles_Homo sapiens_hsa051620.04505911
139TGF-beta signaling pathway_Homo sapiens_hsa043500.04454757
140Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.03823158
141Hepatitis B_Homo sapiens_hsa051610.03671561
142Transcriptional misregulation in cancer_Homo sapiens_hsa052020.02974920
143Pathways in cancer_Homo sapiens_hsa052000.01473691

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