ACSM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.56894450
2L-phenylalanine catabolic process (GO:0006559)7.56894450
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.26726324
4L-phenylalanine metabolic process (GO:0006558)7.26726324
5aromatic amino acid family catabolic process (GO:0009074)6.95487239
6indole-containing compound catabolic process (GO:0042436)6.42355990
7indolalkylamine catabolic process (GO:0046218)6.42355990
8tryptophan catabolic process (GO:0006569)6.42355990
9kynurenine metabolic process (GO:0070189)6.17973431
10glyoxylate metabolic process (GO:0046487)6.06564214
11tryptophan metabolic process (GO:0006568)6.02780251
12bile acid biosynthetic process (GO:0006699)5.95524623
13triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.90865379
14cysteine metabolic process (GO:0006534)5.65542996
15urea metabolic process (GO:0019627)5.49346322
16urea cycle (GO:0000050)5.49346322
17alpha-linolenic acid metabolic process (GO:0036109)5.40440537
18negative regulation of fibrinolysis (GO:0051918)5.37632852
19sulfur amino acid catabolic process (GO:0000098)5.33675425
20epoxygenase P450 pathway (GO:0019373)5.29402609
21high-density lipoprotein particle remodeling (GO:0034375)5.25260654
22serine family amino acid catabolic process (GO:0009071)5.25042711
23complement activation, alternative pathway (GO:0006957)5.20990477
24protein carboxylation (GO:0018214)5.18371571
25peptidyl-glutamic acid carboxylation (GO:0017187)5.18371571
26regulation of fibrinolysis (GO:0051917)5.17443237
27regulation of protein activation cascade (GO:2000257)5.17022449
28lysine metabolic process (GO:0006553)5.10259968
29lysine catabolic process (GO:0006554)5.10259968
30fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.09678383
31nitrogen cycle metabolic process (GO:0071941)5.06536770
32aromatic amino acid family metabolic process (GO:0009072)5.05853372
33bile acid metabolic process (GO:0008206)5.03388177
34homocysteine metabolic process (GO:0050667)4.88252964
35regulation of complement activation (GO:0030449)4.83516347
36tyrosine metabolic process (GO:0006570)4.72825091
37amino-acid betaine metabolic process (GO:0006577)4.72266345
38alpha-amino acid catabolic process (GO:1901606)4.71426264
39regulation of lipoprotein metabolic process (GO:0050746)4.69959554
40ethanol metabolic process (GO:0006067)4.69684306
41negative regulation of protein activation cascade (GO:2000258)4.66933244
42regulation of cholesterol esterification (GO:0010872)4.63316245
43negative regulation of complement activation (GO:0045916)4.62545238
44regulation of triglyceride catabolic process (GO:0010896)4.56011727
45sodium-independent organic anion transport (GO:0043252)4.55650095
46indolalkylamine metabolic process (GO:0006586)4.53844547
47reverse cholesterol transport (GO:0043691)4.53015088
48cellular ketone body metabolic process (GO:0046950)4.49509034
49plasma lipoprotein particle remodeling (GO:0034369)4.49280824
50protein-lipid complex remodeling (GO:0034368)4.49280824
51macromolecular complex remodeling (GO:0034367)4.49280824
52purine nucleotide transport (GO:0015865)4.48366589
53negative regulation of cholesterol transport (GO:0032375)4.44915563
54negative regulation of sterol transport (GO:0032372)4.44915563
55amine catabolic process (GO:0009310)4.43482116
56cellular biogenic amine catabolic process (GO:0042402)4.43482116
57triglyceride homeostasis (GO:0070328)4.39676921
58acylglycerol homeostasis (GO:0055090)4.39676921
59primary alcohol catabolic process (GO:0034310)4.39315929
60coenzyme catabolic process (GO:0009109)4.38138230
61phenylpropanoid metabolic process (GO:0009698)4.37507466
62cellular amino acid catabolic process (GO:0009063)4.36893920
63glycine metabolic process (GO:0006544)4.36074134
64serine family amino acid metabolic process (GO:0009069)4.35783534
65glutamate metabolic process (GO:0006536)4.35693846
66cellular glucuronidation (GO:0052695)4.33245742
67phospholipid efflux (GO:0033700)4.29897868
68oxidative demethylation (GO:0070989)4.28895586
69bile acid and bile salt transport (GO:0015721)4.27550219
70drug catabolic process (GO:0042737)4.25095838
71cellular modified amino acid catabolic process (GO:0042219)4.24771650
72positive regulation of chemokine secretion (GO:0090197)4.23835383
73ethanol oxidation (GO:0006069)4.19133393
74imidazole-containing compound metabolic process (GO:0052803)4.16217957
75hormone catabolic process (GO:0042447)4.14920221
76plasma lipoprotein particle clearance (GO:0034381)4.14833776
77serine family amino acid biosynthetic process (GO:0009070)4.12332070
78biotin metabolic process (GO:0006768)4.05153361
79dicarboxylic acid biosynthetic process (GO:0043650)4.04788680
80urate metabolic process (GO:0046415)4.04731301
81* benzene-containing compound metabolic process (GO:0042537)4.03337357
82aldehyde catabolic process (GO:0046185)4.02978545
83drug metabolic process (GO:0017144)4.02580107
84drug transmembrane transport (GO:0006855)4.01949514
85cholesterol efflux (GO:0033344)3.95608372
86retinal metabolic process (GO:0042574)3.94144940
87arginine metabolic process (GO:0006525)3.93648920
88uronic acid metabolic process (GO:0006063)3.90454857
89glucuronate metabolic process (GO:0019585)3.90454857
90ketone body metabolic process (GO:1902224)3.89253893
91omega-hydroxylase P450 pathway (GO:0097267)3.88960330
92fibrinolysis (GO:0042730)3.87400893
93acetyl-CoA metabolic process (GO:0006084)3.86118403
94calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.85955887
95organic acid catabolic process (GO:0016054)3.82486116
96carboxylic acid catabolic process (GO:0046395)3.82486116
97exogenous drug catabolic process (GO:0042738)3.81239576
98S-adenosylmethionine metabolic process (GO:0046500)3.81187746
99plasma lipoprotein particle assembly (GO:0034377)3.77591030
100low-density lipoprotein particle remodeling (GO:0034374)3.76137061
101aspartate family amino acid catabolic process (GO:0009068)3.73973823
102cofactor catabolic process (GO:0051187)3.72758016
103regulation of bile acid biosynthetic process (GO:0070857)3.71841804
104negative regulation of humoral immune response (GO:0002921)3.70343864
105regulation of cholesterol homeostasis (GO:2000188)3.66798595
106regulation of plasminogen activation (GO:0010755)3.65647858
107complement activation, classical pathway (GO:0006958)3.64616791
108positive regulation of cellular amine metabolic process (GO:0033240)3.63998709
109blood coagulation, intrinsic pathway (GO:0007597)3.63605106
1102-oxoglutarate metabolic process (GO:0006103)3.63062761
111phospholipid homeostasis (GO:0055091)3.59929182
112complement activation (GO:0006956)3.59818741
113cytolysis (GO:0019835)3.59609242
114flavonoid metabolic process (GO:0009812)3.59194759
115very-low-density lipoprotein particle assembly (GO:0034379)3.59035968
116positive regulation of lipoprotein lipase activity (GO:0051006)3.57783646
117positive regulation of triglyceride lipase activity (GO:0061365)3.57783646
118primary alcohol metabolic process (GO:0034308)3.57494032
119heme transport (GO:0015886)3.57009758
120regulation of chemokine secretion (GO:0090196)3.56871889
121positive regulation of lipid catabolic process (GO:0050996)3.56251127
122protein activation cascade (GO:0072376)3.56235478
123linoleic acid metabolic process (GO:0043651)3.55717429
124NAD biosynthetic process (GO:0009435)3.55465774
125carnitine metabolic process (GO:0009437)3.52898247
126phosphatidylethanolamine biosynthetic process (GO:0006646)3.46759492
127positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)3.34155119
128regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)3.34155119
129regulation of cytokine production involved in inflammatory response (GO:1900015)3.32531227
130drug transport (GO:0015893)3.30052623
131response to mercury ion (GO:0046689)3.25957785
132valine metabolic process (GO:0006573)3.21292140
133regulation of humoral immune response (GO:0002920)3.20856093
134phosphatidylethanolamine metabolic process (GO:0046337)3.17751765
135branched-chain amino acid metabolic process (GO:0009081)3.16556249
136regulation of apoptotic cell clearance (GO:2000425)3.16256836
137monocarboxylic acid catabolic process (GO:0072329)3.10709382
138lung lobe morphogenesis (GO:0060463)3.05804342
139alkaloid metabolic process (GO:0009820)3.04203321
140disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.03080373
141killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.03080373
142* short-chain fatty acid metabolic process (GO:0046459)3.03046606
143negative regulation of hemostasis (GO:1900047)3.02365183
144negative regulation of blood coagulation (GO:0030195)3.02365183
145acute-phase response (GO:0006953)3.01594087
146* xenobiotic metabolic process (GO:0006805)3.01494916
147steroid catabolic process (GO:0006706)3.00963368
148lung vasculature development (GO:0060426)2.99874335
149* fatty acid oxidation (GO:0019395)2.97898962
150negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.97643131

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.33463323
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.14587825
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.93257763
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.44038689
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.18302704
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.97798108
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.90598227
8* NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.97908476
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.97901932
10PIAS1_25552417_ChIP-Seq_VCAP_Human2.54093648
11TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.09980996
12FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.07315417
13HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.07139932
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05491313
15ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.8445717
16CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.70671127
17AR_21909140_ChIP-Seq_LNCAP_Human1.63730249
18* FOXA2_19822575_ChIP-Seq_HepG2_Human1.61518435
19CLOCK_20551151_ChIP-Seq_293T_Human1.57852053
20ZNF217_24962896_ChIP-Seq_MCF-7_Human1.53751357
21TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53443017
22HTT_18923047_ChIP-ChIP_STHdh_Human1.44666758
23* HNF4A_19822575_ChIP-Seq_HepG2_Human1.44061340
24AHR_22903824_ChIP-Seq_MCF-7_Human1.42849281
25AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.41146436
26* GATA3_24758297_ChIP-Seq_MCF-7_Human1.32852128
27GATA1_22025678_ChIP-Seq_K562_Human1.31760831
28CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.24598480
29STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.24551968
30* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.22336368
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.21815092
32HNFA_21074721_ChIP-Seq_CACO-2_Human1.20846609
33NFE2_27457419_Chip-Seq_LIVER_Mouse1.18613341
34RXRA_24833708_ChIP-Seq_LIVER_Mouse1.18472498
35PHF8_20622853_ChIP-Seq_HELA_Human1.16549885
36ER_23166858_ChIP-Seq_MCF-7_Human1.16305731
37TRIM28_21343339_ChIP-Seq_HEK293_Human1.15980977
38ARNT_22903824_ChIP-Seq_MCF-7_Human1.15577493
39GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.13628948
40EZH2_27294783_Chip-Seq_NPCs_Mouse1.11915769
41GATA6_21074721_ChIP-Seq_CACO-2_Human1.11668293
42RXR_22108803_ChIP-Seq_LS180_Human1.09166368
43TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.09048473
44SUZ12_27294783_Chip-Seq_NPCs_Mouse1.07554653
45IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.07190262
46ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06638423
47GATA3_21878914_ChIP-Seq_MCF-7_Human1.06368141
48ETV1_20927104_ChIP-Seq_GIST48_Human1.04676219
49IGF1R_20145208_ChIP-Seq_DFB_Human1.03395957
50ERA_21632823_ChIP-Seq_H3396_Human1.01326016
51NFYA_21822215_ChIP-Seq_K562_Human1.01095886
52STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.99929816
53GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98947367
54SOX2_18555785_Chip-Seq_ESCs_Mouse0.98402346
55ESR1_15608294_ChIP-ChIP_MCF-7_Human0.98370434
56KLF4_18555785_Chip-Seq_ESCs_Mouse0.97979549
57ZFX_18555785_Chip-Seq_ESCs_Mouse0.97806982
58RARG_19884340_ChIP-ChIP_MEFs_Mouse0.97685535
59ZNF274_21170338_ChIP-Seq_K562_Hela0.97484688
60TBL1_22424771_ChIP-Seq_293T_Human0.97294565
61* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.96163927
62CDX2_19796622_ChIP-Seq_MESCs_Mouse0.95273806
63RBPJ_21746931_ChIP-Seq_IB4_Human0.94179889
64STAT3_18555785_Chip-Seq_ESCs_Mouse0.93032678
65RUNX1_27457419_Chip-Seq_LIVER_Mouse0.93030051
66NFYB_21822215_ChIP-Seq_K562_Human0.92597720
67CTCF_18555785_Chip-Seq_ESCs_Mouse0.91898917
68GATA2_21666600_ChIP-Seq_HMVEC_Human0.91846948
69PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.91335232
70SUZ12_18555785_Chip-Seq_ESCs_Mouse0.91325505
71PU1_27457419_Chip-Seq_LIVER_Mouse0.90477161
72OCT1_27270436_Chip-Seq_PROSTATE_Human0.89711402
73CBX2_22325352_ChIP-Seq_293T-Rex_Human0.89354211
74ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.89229215
75P300_18555785_Chip-Seq_ESCs_Mouse0.88639900
76RUNX1_27514584_Chip-Seq_MCF-7_Human0.87420022
77TCF4_18268006_ChIP-ChIP_LS174T_Human0.87327978
78ESRRB_18555785_Chip-Seq_ESCs_Mouse0.87069569
79PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.86865269
80IRF8_22096565_ChIP-ChIP_GC-B_Human0.86788423
81NFIB_24661679_ChIP-Seq_LUNG_Mouse0.86487208
82GATA4_25053715_ChIP-Seq_YYC3_Human0.86344540
83STAT1_20625510_ChIP-Seq_HELA_Human0.85624113
84FOXA1_21572438_ChIP-Seq_LNCaP_Human0.84436425
85POU3F2_20337985_ChIP-ChIP_501MEL_Human0.82923987
86KAP1_22055183_ChIP-Seq_ESCs_Mouse0.79098095
87ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.78948318
88ESR2_21235772_ChIP-Seq_MCF-7_Human0.78189997
89* AUTS2_25519132_ChIP-Seq_293T-REX_Human0.77244788
90SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.75981806
91Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.73554858
92* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.72266070
93RARA_24833708_ChIP-Seq_LIVER_Mouse0.72153407
94CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.71590739
95SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.71383347
96ZNF263_19887448_ChIP-Seq_K562_Human0.70348982
97RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.69583655
98* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.68568007
99SALL4_18804426_ChIP-ChIP_XEN_Mouse0.68499878
100NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.67346324
101NRF2_20460467_ChIP-Seq_MEFs_Mouse0.67067763
102NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.67067763
103ESR1_21235772_ChIP-Seq_MCF-7_Human0.66939791
104* PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.65593984
105RAD21_21589869_ChIP-Seq_MESCs_Mouse0.64368013
106BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.63013689
107NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.62668690
108RARB_24833708_ChIP-Seq_LIVER_Mouse0.61062533
109STAT3_1855785_ChIP-Seq_MESCs_Mouse0.59542043
110CEBPB_22108803_ChIP-Seq_LS180_Human0.59411116
111EGR1_19032775_ChIP-ChIP_M12_Human0.59296181
112LXR_22292898_ChIP-Seq_THP-1_Human0.58261554
113CDX2_20551321_ChIP-Seq_CACO-2_Human0.56839810
114AR_20517297_ChIP-Seq_VCAP_Human0.54540851
115MYC_19915707_ChIP-ChIP_AK7_Human0.54188111
116PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.53016135
117FOXA1_25552417_ChIP-Seq_VCAP_Human0.52688841
118* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.52066192
119ESET_19884257_ChIP-Seq_ESCs_Mouse0.51378192
120STAT1_17558387_ChIP-Seq_HELA_Human0.49056020
121CBP_21632823_ChIP-Seq_H3396_Human0.48634727
122FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.48344131
123E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.47993689
124FOXO3_23340844_ChIP-Seq_DLD1_Human0.47236007
125PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.45812748
126NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.45554483
127P53_21459846_ChIP-Seq_SAOS-2_Human0.45082618
128GATA6_25053715_ChIP-Seq_YYC3_Human0.44902773
129TAF2_19829295_ChIP-Seq_ESCs_Human0.44363555
130PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.44176549
131FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.43422646
132GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.43304535
133TAF15_26573619_Chip-Seq_HEK293_Human0.42933263
134FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.42811078
135ESR1_20079471_ChIP-ChIP_T-47D_Human0.42726102
136PPAR_26484153_Chip-Seq_NCI-H1993_Human0.41839894
137SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.41539797
138GATA1_19941827_ChIP-Seq_MEL_Mouse0.41246698
139BCAT_22108803_ChIP-Seq_LS180_Human0.40823160
140PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.40806405
141GATA2_19941826_ChIP-Seq_K562_Human0.40475399
142ERG_21242973_ChIP-ChIP_JURKAT_Human0.40367892
143STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.40112798
144GATA1_19941826_ChIP-Seq_K562_Human0.39646781
145CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.39074333
146MYC_27129775_Chip-Seq_CORNEA_Mouse0.36651972
147CDX2_22108803_ChIP-Seq_LS180_Human0.36616613
148NCOR_22424771_ChIP-Seq_293T_Human0.36019786
149EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.35940927
150SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.35887543
151SOX2_20726797_ChIP-Seq_SW620_Human0.35580248
152LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.35121856
153ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.34993991

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.37404546
2MP0005360_urolithiasis7.80881423
3MP0005085_abnormal_gallbladder_physiolo6.30558953
4MP0005365_abnormal_bile_salt6.08357872
5MP0008875_abnormal_xenobiotic_pharmacok5.11735188
6MP0003806_abnormal_nucleotide_metabolis4.13516004
7MP0003252_abnormal_bile_duct3.89228997
8MP0010329_abnormal_lipoprotein_level3.41524071
9MP0003183_abnormal_peptide_metabolism3.07590279
10MP0009840_abnormal_foam_cell3.02396935
11MP0005332_abnormal_amino_acid3.02306904
12MP0003195_calcinosis2.99657551
13MP0005083_abnormal_biliary_tract2.93397476
14MP0001666_abnormal_nutrient_absorption2.54678707
15MP0002132_abnormal_respiratory_system2.52024825
16MP0003300_gastrointestinal_ulcer2.47232870
17MP0004019_abnormal_vitamin_homeostasis2.43552171
18MP0010386_abnormal_urinary_bladder2.25931046
19MP0003191_abnormal_cellular_cholesterol2.25906177
20MP0003136_yellow_coat_color2.24528847
21MP0002138_abnormal_hepatobiliary_system2.20729028
22MP0000609_abnormal_liver_physiology2.08514962
23MP0002118_abnormal_lipid_homeostasis2.04664119
24MP0005319_abnormal_enzyme/_coenzyme1.84759684
25MP0003868_abnormal_feces_composition1.79360957
26MP0005409_darkened_coat_color1.70573115
27MP0001188_hyperpigmentation1.70402156
28MP0001764_abnormal_homeostasis1.66141653
29MP0005584_abnormal_enzyme/coenzyme_acti1.60378649
30MP0009643_abnormal_urine_homeostasis1.50154919
31MP0009697_abnormal_copulation1.43008945
32MP0005397_hematopoietic_system_phenotyp1.42868182
33MP0001545_abnormal_hematopoietic_system1.42868182
34MP0005167_abnormal_blood-brain_barrier1.41271953
35MP0005451_abnormal_body_composition1.39411352
36MP0003186_abnormal_redox_activity1.34141153
37MP0005410_abnormal_fertilization1.29919369
38MP0003011_delayed_dark_adaptation1.27696700
39MP0005310_abnormal_salivary_gland1.27432025
40MP0005636_abnormal_mineral_homeostasis1.15384018
41MP0000598_abnormal_liver_morphology1.14562009
42MP0003656_abnormal_erythrocyte_physiolo1.12295328
43MP0004147_increased_porphyrin_level1.10196061
44MP0005647_abnormal_sex_gland1.09927727
45MP0009764_decreased_sensitivity_to1.06836852
46MP0003705_abnormal_hypodermis_morpholog1.06622959
47MP0000604_amyloidosis1.01798968
48MP0003879_abnormal_hair_cell0.99017882
49MP0009763_increased_sensitivity_to0.96417905
50MP0003866_abnormal_defecation0.95715066
51MP0004233_abnormal_muscle_weight0.91816412
52MP0002254_reproductive_system_inflammat0.90063787
53MP0008469_abnormal_protein_level0.89524490
54MP0003941_abnormal_skin_development0.88801823
55MP0009642_abnormal_blood_homeostasis0.88316451
56MP0005084_abnormal_gallbladder_morpholo0.88244065
57MP0010368_abnormal_lymphatic_system0.88023227
58MP0002735_abnormal_chemical_nociception0.87223768
59MP0002166_altered_tumor_susceptibility0.87168008
60MP0006036_abnormal_mitochondrial_physio0.86010440
61MP0002876_abnormal_thyroid_physiology0.85309173
62MP0003045_fibrosis0.84188448
63MP0001944_abnormal_pancreas_morphology0.83983649
64MP0005670_abnormal_white_adipose0.83778922
65MP0005408_hypopigmentation0.83653315
66MP0001756_abnormal_urination0.80868070
67MP0009785_altered_susceptibility_to0.79136033
68MP0005376_homeostasis/metabolism_phenot0.76698007
69MP0000371_diluted_coat_color0.76169030
70MP0002078_abnormal_glucose_homeostasis0.75601005
71MP0009765_abnormal_xenobiotic_induced0.75535674
72MP0005220_abnormal_exocrine_pancreas0.74832895
73MP0002089_abnormal_postnatal_growth/wei0.73995971
74MP0001727_abnormal_embryo_implantation0.72466513
75MP0002396_abnormal_hematopoietic_system0.71786917
76MP0005535_abnormal_body_temperature0.71608875
77MP0001661_extended_life_span0.70622899
78MP0002971_abnormal_brown_adipose0.68561564
79MP0002136_abnormal_kidney_physiology0.67373758
80MP0000015_abnormal_ear_pigmentation0.66388712
81MP0001485_abnormal_pinna_reflex0.64256131
82MP0005334_abnormal_fat_pad0.64250829
83MP0003690_abnormal_glial_cell0.64170533
84MP0003329_amyloid_beta_deposits0.63634991
85MP0004043_abnormal_pH_regulation0.63286477
86MP0004130_abnormal_muscle_cell0.61780436
87MP0005174_abnormal_tail_pigmentation0.61632183
88MP0009053_abnormal_anal_canal0.61217353
89MP0005266_abnormal_metabolism0.61023355
90MP0005646_abnormal_pituitary_gland0.59687173
91MP0004885_abnormal_endolymph0.58980741
92MP0001664_abnormal_digestion0.58867965
93MP0006035_abnormal_mitochondrial_morpho0.57157560
94MP0004808_abnormal_hematopoietic_stem0.57013525
95MP0003698_abnormal_male_reproductive0.56524150
96MP0002928_abnormal_bile_duct0.55387050
97MP0008995_early_reproductive_senescence0.54333648
98MP0000639_abnormal_adrenal_gland0.51449180
99MP0005395_other_phenotype0.50821170
100MP0003638_abnormal_response/metabolism_0.50365630
101MP0001929_abnormal_gametogenesis0.49332227
102MP0005023_abnormal_wound_healing0.49324348
103MP0005448_abnormal_energy_balance0.48194494
104MP0005464_abnormal_platelet_physiology0.46510683
105MP0003724_increased_susceptibility_to0.44984021
106MP0001765_abnormal_ion_homeostasis0.44876555
107MP0008874_decreased_physiological_sensi0.44167642
108MP0003718_maternal_effect0.41774283
109MP0003953_abnormal_hormone_level0.41274097
110MP0008873_increased_physiological_sensi0.41259857
111MP0005666_abnormal_adipose_tissue0.41181625
112MP0002822_catalepsy0.41055972
113MP0004782_abnormal_surfactant_physiolog0.40554750
114MP0005058_abnormal_lysosome_morphology0.39672664
115MP0003075_altered_response_to0.39448878
116MP0002168_other_aberrant_phenotype0.38863816
117MP0005166_decreased_susceptibility_to0.38299079
118MP0002796_impaired_skin_barrier0.37807929
119MP0000230_abnormal_systemic_arterial0.37643254
120MP0003436_decreased_susceptibility_to0.36267978
121MP0009672_abnormal_birth_weight0.35633418
122MP0008872_abnormal_physiological_respon0.35279338
123MP0004381_abnormal_hair_follicle0.35093711
124MP0002837_dystrophic_cardiac_calcinosis0.34724439
125MP0005248_abnormal_Harderian_gland0.34131433
126MP0000579_abnormal_nail_morphology0.33600236
127MP0009384_cardiac_valve_regurgitation0.32170629
128MP0006082_CNS_inflammation0.30609802
129MP0009115_abnormal_fat_cell0.30601625
130MP0002135_abnormal_kidney_morphology0.30109870
131MP0000249_abnormal_blood_vessel0.27839433
132MP0001845_abnormal_inflammatory_respons0.27674544
133MP0002970_abnormal_white_adipose0.27312453
134MP0004264_abnormal_extraembryonic_tissu0.27090513
135MP0000538_abnormal_urinary_bladder0.26648191
136MP0001881_abnormal_mammary_gland0.25134651
137MP0001853_heart_inflammation0.24327914

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.23484561
2Intrahepatic cholestasis (HP:0001406)7.15890681
3Deep venous thrombosis (HP:0002625)7.02349427
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.44889521
5Prolonged partial thromboplastin time (HP:0003645)6.20843443
6Xanthomatosis (HP:0000991)6.06505904
7Hypobetalipoproteinemia (HP:0003563)5.96996984
8Complement deficiency (HP:0004431)5.23590491
9Hyperlipoproteinemia (HP:0010980)5.17741862
10Joint hemorrhage (HP:0005261)4.63589695
11Hyperammonemia (HP:0001987)4.62936435
12Hyperglycinemia (HP:0002154)4.53537369
13Abnormality of glutamine family amino acid metabolism (HP:0010902)4.48681146
14Hypolipoproteinemia (HP:0010981)4.45845527
15Ketosis (HP:0001946)4.44360263
16Severe visual impairment (HP:0001141)4.39779670
17Hyperglycinuria (HP:0003108)4.29942992
18Epidermoid cyst (HP:0200040)4.27494275
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.27218121
20Abnormality of the common coagulation pathway (HP:0010990)4.25754095
21Abnormality of aspartate family amino acid metabolism (HP:0010899)4.22195413
22Abnormality of glycine metabolism (HP:0010895)4.18312739
23Abnormality of serine family amino acid metabolism (HP:0010894)4.18312739
24Cerebral palsy (HP:0100021)4.18271086
25Seborrheic dermatitis (HP:0001051)4.17785350
26Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.07065351
27Fat malabsorption (HP:0002630)4.06902673
28Abnormality of methionine metabolism (HP:0010901)4.05080980
29Hypoalphalipoproteinemia (HP:0003233)3.88709620
30Hypoglycemic coma (HP:0001325)3.81010357
31Abnormality of complement system (HP:0005339)3.79319152
32Abnormality of pyrimidine metabolism (HP:0004353)3.75015485
33Conjugated hyperbilirubinemia (HP:0002908)3.61892966
34Abnormality of the intrinsic pathway (HP:0010989)3.57718351
35Reduced antithrombin III activity (HP:0001976)3.56986568
36Abnormality of fatty-acid metabolism (HP:0004359)3.50287257
37Hypercholesterolemia (HP:0003124)3.38328218
38Ketoacidosis (HP:0001993)3.33217451
39Abnormality of nucleobase metabolism (HP:0010932)3.32443894
40Delayed CNS myelination (HP:0002188)3.31000075
41Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.28602162
42Hyperbilirubinemia (HP:0002904)3.26029380
43Azoospermia (HP:0000027)3.21570298
44Gout (HP:0001997)3.17494540
45Abnormality of purine metabolism (HP:0004352)3.11158098
46Ileus (HP:0002595)3.09801574
47Abnormality of serum amino acid levels (HP:0003112)3.09299540
48Steatorrhea (HP:0002570)3.08357977
49Hepatocellular carcinoma (HP:0001402)2.96427353
50Abnormality of the heme biosynthetic pathway (HP:0010472)2.95319821
51Metabolic acidosis (HP:0001942)2.88447584
52Spontaneous abortion (HP:0005268)2.87542687
53Myocardial infarction (HP:0001658)2.80919756
54Vascular calcification (HP:0004934)2.80690233
55Attenuation of retinal blood vessels (HP:0007843)2.80615697
56Abnormality of macular pigmentation (HP:0008002)2.80435608
57Hypochromic microcytic anemia (HP:0004840)2.74429533
58Nephritis (HP:0000123)2.74360025
59Abnormality of dicarboxylic acid metabolism (HP:0010995)2.71707721
60Dicarboxylic aciduria (HP:0003215)2.71707721
61Lethargy (HP:0001254)2.71437529
62Systemic lupus erythematosus (HP:0002725)2.70812408
63Skin nodule (HP:0200036)2.61835025
64Beaking of vertebral bodies (HP:0004568)2.54144082
65Spastic diplegia (HP:0001264)2.49707713
66Cardiovascular calcification (HP:0011915)2.48811769
67Neonatal onset (HP:0003623)2.46496274
68Cerebral edema (HP:0002181)2.45332093
69Irritability (HP:0000737)2.44880676
70Scotoma (HP:0000575)2.42500016
71Hypoglycemic seizures (HP:0002173)2.41616446
72Male infertility (HP:0003251)2.40866744
73Generalized aminoaciduria (HP:0002909)2.40695260
74Right ventricular cardiomyopathy (HP:0011663)2.40380866
75Joint swelling (HP:0001386)2.39969579
76Malnutrition (HP:0004395)2.38708241
77Mitral stenosis (HP:0001718)2.38016321
78Hypothermia (HP:0002045)2.36461866
79Glomerulonephritis (HP:0000099)2.33861205
80Acanthocytosis (HP:0001927)2.33066305
81Abnormal gallbladder morphology (HP:0012437)2.32420161
82Exocrine pancreatic insufficiency (HP:0001738)2.30163973
83Abnormal rod and cone electroretinograms (HP:0008323)2.29178390
84Recurrent gram-negative bacterial infections (HP:0005420)2.29117830
85Abnormal tarsal ossification (HP:0008369)2.28666455
86Alkalosis (HP:0001948)2.27944794
87Cholelithiasis (HP:0001081)2.27099337
88Sensorimotor neuropathy (HP:0007141)2.26687066
89Enlarged kidneys (HP:0000105)2.25716689
90Late onset (HP:0003584)2.24990569
91Proximal tubulopathy (HP:0000114)2.23418378
92Vomiting (HP:0002013)2.23409046
93Increased purine levels (HP:0004368)2.20562555
94Hyperuricemia (HP:0002149)2.20562555
95Facial shape deformation (HP:0011334)2.20212714
96Potter facies (HP:0002009)2.20212714
97Abnormal gallbladder physiology (HP:0012438)2.18520903
98Cholecystitis (HP:0001082)2.18520903
99Rickets (HP:0002748)2.16526450
100Abnormality of carpal bone ossification (HP:0006257)2.16093772
101Pancreatitis (HP:0001733)2.14638830
102Amyloidosis (HP:0011034)2.14190025
103Growth hormone excess (HP:0000845)2.13095980
104Esophageal varix (HP:0002040)2.12083225
105Arthropathy (HP:0003040)2.11931010
106Abnormal spermatogenesis (HP:0008669)2.11062651
107Abnormal hemoglobin (HP:0011902)2.08468937
108Hydroxyprolinuria (HP:0003080)2.07772040
109Abnormality of proline metabolism (HP:0010907)2.07772040
110Brushfield spots (HP:0001088)2.05793024
111Gingival bleeding (HP:0000225)2.05380835
112Menorrhagia (HP:0000132)2.05231889
113Opisthotonus (HP:0002179)2.04908558
114Thrombophlebitis (HP:0004418)2.04133969
115Abnormal enzyme/coenzyme activity (HP:0012379)2.01503216
116Chronic hepatic failure (HP:0100626)1.99291112
117Abnormality of urine glucose concentration (HP:0011016)1.96892241
118Glycosuria (HP:0003076)1.96892241
119Increased serum ferritin (HP:0003281)1.96731808
120Hypophosphatemic rickets (HP:0004912)1.95175000
121Hyperinsulinemic hypoglycemia (HP:0000825)1.95152565
122Bony spicule pigmentary retinopathy (HP:0007737)1.95088217
123Abnormality of the gallbladder (HP:0005264)1.93572245
124Fair hair (HP:0002286)1.92704547
125Hemorrhage of the eye (HP:0011885)1.91002488
126Abnormality of transition element cation homeostasis (HP:0011030)1.89710717
127Neonatal death (HP:0003811)1.89343915
128Severe Myopia (HP:0011003)1.88757209
129Abnormality of iron homeostasis (HP:0011031)1.88030142
130Abnormal cartilage morphology (HP:0002763)1.87685070
131Abnormal hand bone ossification (HP:0010660)1.86141375
132Pulmonary embolism (HP:0002204)1.85097265
133Esophageal neoplasm (HP:0100751)1.84584360
134Neoplasm of head and neck (HP:0012288)1.84584360
135Reticulocytosis (HP:0001923)1.83261031
136Abnormal biliary tract physiology (HP:0012439)1.83104082
137Bile duct proliferation (HP:0001408)1.83104082
138Poikilocytosis (HP:0004447)1.82244512
139Testicular neoplasm (HP:0010788)1.82139963
140Tubulointerstitial nephritis (HP:0001970)1.81816326
141Renal cortical cysts (HP:0000803)1.81365964
142Abnormality of the axillary hair (HP:0100134)1.80182585
143Abnormality of secondary sexual hair (HP:0009888)1.80182585
144Epiphyseal stippling (HP:0010655)1.79105020
145Generalized hypopigmentation of hair (HP:0011358)1.77842805
146Neoplasm of the lung (HP:0100526)1.76552188
147Submucous cleft hard palate (HP:0000176)1.75439791
148Prolonged bleeding time (HP:0003010)1.75151306
149Congenital sensorineural hearing impairment (HP:0008527)1.75141196

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.31160683
2LMTK25.59821720
3FGFR44.60502418
4AKT34.49656703
5ERN14.26330649
6SIK14.22177198
7PIK3CA3.78554134
8TAOK32.95512510
9ERBB42.92149314
10INSRR2.85771369
11TNK22.72612556
12MST1R2.21836382
13MAP2K42.20006168
14ILK2.03499503
15PKN21.93152556
16MYLK1.93136964
17MAPK111.91444579
18STK391.76037530
19PIK3CG1.74616101
20TRIB31.68015307
21FLT31.65385372
22LATS11.61627083
23DAPK21.57604844
24TYK21.57263884
25FER1.48271225
26ABL21.46553097
27PTK61.46370345
28CDK121.44932270
29PIM21.41744237
30STK38L1.40824490
31NEK91.33367878
32NTRK31.32081498
33FRK1.31689523
34MAP3K121.31161992
35FGFR21.29604530
36WNK31.28640265
37MAP3K71.26414243
38PINK11.25937079
39JAK21.19463561
40KDR1.17259880
41GRK61.17042000
42MARK21.14152751
43WNK41.13537045
44DMPK1.13258601
45EIF2AK11.12560325
46PRKAA21.10848454
47BRSK21.08275093
48NUAK11.03649118
49MAP2K31.00827264
50MAP4K21.00217529
51ERBB20.99659719
52RIPK40.99205843
53MAP3K140.98465294
54TNIK0.98003276
55TBK10.96658619
56EPHB10.96648513
57PRKD20.95883904
58SGK10.94578013
59PRKCZ0.92604480
60JAK10.92360814
61BMPR1B0.92300429
62BRD40.92086834
63EIF2AK30.90470256
64MAPK40.89929121
65TIE10.89627916
66NME10.89180314
67PLK40.89028704
68MAPK150.88277769
69CDK90.87356423
70MAP3K30.86848461
71HIPK20.85963647
72WNK10.85548718
73NEK60.84868417
74MAP3K100.84734215
75MET0.84431676
76OXSR10.84291638
77SGK30.80596078
78DYRK1B0.79826814
79MAPK120.77561835
80GSK3A0.74946980
81PRKACG0.74549665
82MAP3K110.73664724
83TESK10.71275230
84PRKAA10.70373525
85CDK60.69006169
86SGK4940.68734730
87SGK2230.68734730
88PRKG20.68530898
89EPHA30.68291436
90CAMK2G0.67586787
91IRAK30.67270448
92SGK20.66001019
93BTK0.65883003
94TGFBR20.64338916
95CSK0.63895400
96NLK0.63871273
97MAP2K60.63598252
98PTK20.62876409
99STK240.62787571
100JAK30.61706299
101TAOK10.61604476
102PRKD10.60399100
103RIPK10.59634326
104RPS6KB20.58441223
105TRPM70.57938483
106ERBB30.57367148
107PDK30.57185487
108PDK40.57185487
109RPS6KA40.56938496
110PDPK10.56537690
111CAMK1D0.55845877
112FGFR30.52917095
113TEC0.52683956
114CAMK1G0.51660813
115YES10.50271399
116MARK30.50233004
117MAPK30.50103232
118MAPK70.49884580
119PRKCQ0.48216985
120IKBKE0.47936304
121EPHA40.47798733
122PRKG10.47778241
123RPS6KA50.46902546
124CSF1R0.45976500
125LRRK20.44197680
126CSNK1G10.43813645
127IGF1R0.42406588
128RAF10.41897118
129MAPK100.40691732
130PKN10.40109228
131GRK10.39536453
132STK110.39529881
133PRKACA0.39209915
134ADRBK20.38827266
135RPS6KA30.38447014
136MAP2K10.38099531
137PRKCG0.37838791
138MAP3K130.36457375
139MAP3K50.36396384
140MINK10.35694956
141TAOK20.35288676
142ICK0.34762227
143CSNK1E0.34697151
144PRKCE0.34235405
145MTOR0.34200246
146PDK10.34092578
147RET0.33479523
148EGFR0.32516141
149CAMK40.31004718
150NEK10.30523578
151IRAK20.30395924
152CDK40.29896641
153IRAK10.29860277
154STK380.29289692
155MAP3K60.28211073
156PRKCA0.27338153
157PAK30.25354335
158MAP3K10.24041395
159PBK0.23102179
160PDK20.21950542

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.43162938
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.42119324
3Nitrogen metabolism_Homo sapiens_hsa009103.41767298
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.29878011
5Arginine biosynthesis_Homo sapiens_hsa002202.97460766
6Tryptophan metabolism_Homo sapiens_hsa003802.73893223
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.71978734
8Complement and coagulation cascades_Homo sapiens_hsa046102.63251778
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.61216854
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.54792555
11Fatty acid degradation_Homo sapiens_hsa000712.50255809
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.47569653
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.35960444
14Peroxisome_Homo sapiens_hsa041462.16985362
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.15612147
16* Butanoate metabolism_Homo sapiens_hsa006502.09437257
17Propanoate metabolism_Homo sapiens_hsa006402.03284689
18Chemical carcinogenesis_Homo sapiens_hsa052041.94695430
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.92435815
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.89700875
21Histidine metabolism_Homo sapiens_hsa003401.87690813
22PPAR signaling pathway_Homo sapiens_hsa033201.83393232
23Fatty acid metabolism_Homo sapiens_hsa012121.80382502
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.75609348
25beta-Alanine metabolism_Homo sapiens_hsa004101.75431312
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.73610313
27Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.69492297
28Retinol metabolism_Homo sapiens_hsa008301.67666533
29Caffeine metabolism_Homo sapiens_hsa002321.66389407
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.65674699
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.65076858
32Staphylococcus aureus infection_Homo sapiens_hsa051501.63892973
33Selenocompound metabolism_Homo sapiens_hsa004501.58904550
34Bile secretion_Homo sapiens_hsa049761.54137360
35Phenylalanine metabolism_Homo sapiens_hsa003601.54045215
36Pyruvate metabolism_Homo sapiens_hsa006201.45528739
37Sulfur metabolism_Homo sapiens_hsa009201.41879656
38Tyrosine metabolism_Homo sapiens_hsa003501.40921542
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.39136032
40Starch and sucrose metabolism_Homo sapiens_hsa005001.30513027
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.28693068
42Fatty acid elongation_Homo sapiens_hsa000621.27772315
43Cyanoamino acid metabolism_Homo sapiens_hsa004601.25499372
44Folate biosynthesis_Homo sapiens_hsa007901.21995197
45Biosynthesis of amino acids_Homo sapiens_hsa012301.19548479
46Carbon metabolism_Homo sapiens_hsa012001.17409846
47Steroid biosynthesis_Homo sapiens_hsa001001.16362044
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.15993048
49ABC transporters_Homo sapiens_hsa020101.15220661
50Fat digestion and absorption_Homo sapiens_hsa049751.06837650
51Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.03017271
52Maturity onset diabetes of the young_Homo sapiens_hsa049501.01602421
53Arginine and proline metabolism_Homo sapiens_hsa003301.00686426
54Vitamin digestion and absorption_Homo sapiens_hsa049770.97545537
55Other glycan degradation_Homo sapiens_hsa005110.95501078
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.94865513
57Sulfur relay system_Homo sapiens_hsa041220.92972657
58Vitamin B6 metabolism_Homo sapiens_hsa007500.91857366
59Lysine degradation_Homo sapiens_hsa003100.85876098
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84821284
61Glutathione metabolism_Homo sapiens_hsa004800.78657582
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74659504
63One carbon pool by folate_Homo sapiens_hsa006700.71050988
64Pancreatic secretion_Homo sapiens_hsa049720.70084909
65Glycerolipid metabolism_Homo sapiens_hsa005610.68545521
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.62130235
67Circadian rhythm_Homo sapiens_hsa047100.61827220
68Pentose phosphate pathway_Homo sapiens_hsa000300.57633179
69* Metabolic pathways_Homo sapiens_hsa011000.46713969
70Fatty acid biosynthesis_Homo sapiens_hsa000610.45044949
71Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.37931534
72Prion diseases_Homo sapiens_hsa050200.33000899
73Fructose and mannose metabolism_Homo sapiens_hsa000510.28247281
74Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.25210648
75Olfactory transduction_Homo sapiens_hsa047400.25208062
76Galactose metabolism_Homo sapiens_hsa000520.24086955
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22559547
78Insulin resistance_Homo sapiens_hsa049310.21490744
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.19879553
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19549099
81Linoleic acid metabolism_Homo sapiens_hsa005910.16734693
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.15113101
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.11831068
84Pertussis_Homo sapiens_hsa051330.11446488
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.10180348
86Jak-STAT signaling pathway_Homo sapiens_hsa046300.10024875
87Serotonergic synapse_Homo sapiens_hsa047260.09759456
88Glucagon signaling pathway_Homo sapiens_hsa049220.08139330
89Renin secretion_Homo sapiens_hsa049240.05113492
90Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.04754216
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.01300679
92Sphingolipid metabolism_Homo sapiens_hsa006000.01254983
93Type II diabetes mellitus_Homo sapiens_hsa049300.01087233
94AMPK signaling pathway_Homo sapiens_hsa041520.00931771
95Ether lipid metabolism_Homo sapiens_hsa005650.00291499
96Lysosome_Homo sapiens_hsa04142-0.2290355
97Bladder cancer_Homo sapiens_hsa05219-0.2269453
98Mineral absorption_Homo sapiens_hsa04978-0.2143927
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2082974
100Protein digestion and absorption_Homo sapiens_hsa04974-0.2026971
101African trypanosomiasis_Homo sapiens_hsa05143-0.1905333
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1900912
103Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1742823
104Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1723326
105Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1721445
106Hepatitis C_Homo sapiens_hsa05160-0.1692843
107Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1413763
108Renin-angiotensin system_Homo sapiens_hsa04614-0.1347702
109Regulation of autophagy_Homo sapiens_hsa04140-0.1293235
110Insulin signaling pathway_Homo sapiens_hsa04910-0.1207004
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1197103
112Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1196080
113Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0975960
114Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0946460
115Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0902899
116Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0333933
117Leukocyte transendothelial migration_Homo sapiens_hsa04670-0.0188395
118Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060-0.0178279
119Tight junction_Homo sapiens_hsa04530-0.0152008

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