ACCS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)4.61084506
2positive regulation by organism of defense response of other organism involved in symbiotic interact4.46239899
3modulation by symbiont of host immune response (GO:0052553)4.46239899
4positive regulation by symbiont of host defense response (GO:0052509)4.46239899
5modulation by symbiont of host defense response (GO:0052031)4.46239899
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.46239899
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.46239899
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.45816341
9positive regulation of B cell differentiation (GO:0045579)4.44278927
10mannose metabolic process (GO:0006013)4.20050594
11regulation of B cell receptor signaling pathway (GO:0050855)4.05912864
12definitive hemopoiesis (GO:0060216)3.87801821
13regulation of interferon-beta biosynthetic process (GO:0045357)3.84536511
14neutrophil activation involved in immune response (GO:0002283)3.76366872
15lymphoid progenitor cell differentiation (GO:0002320)3.60874405
16response to host immune response (GO:0052572)3.60410088
17response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.60410088
18negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.59883539
19negative regulation of cell killing (GO:0031342)3.59883539
20regulation of B cell differentiation (GO:0045577)3.56790627
21dendritic cell chemotaxis (GO:0002407)3.52260399
22antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.52160124
23antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.52160124
24response to host (GO:0075136)3.49164263
25response to host defenses (GO:0052200)3.49164263
26response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.49164263
27polyketide metabolic process (GO:0030638)3.48243095
28doxorubicin metabolic process (GO:0044598)3.48243095
29daunorubicin metabolic process (GO:0044597)3.48243095
30leukocyte aggregation (GO:0070486)3.47226545
31dendritic cell migration (GO:0036336)3.37957279
32detection of bacterium (GO:0016045)3.37945830
33ribosomal small subunit assembly (GO:0000028)3.37662397
34negative regulation of phagocytosis (GO:0050765)3.33755942
35regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.31403146
36detection of other organism (GO:0098543)3.31129318
37macrophage activation involved in immune response (GO:0002281)3.29141959
38secretory granule organization (GO:0033363)3.28832670
39positive thymic T cell selection (GO:0045059)3.27487983
40defense response to protozoan (GO:0042832)3.22075112
41negative thymic T cell selection (GO:0045060)3.20930063
42germinal center formation (GO:0002467)3.20138069
43negative regulation of granulocyte differentiation (GO:0030853)3.17817975
44microglial cell activation (GO:0001774)3.15998237
45platelet dense granule organization (GO:0060155)3.15757326
46antigen processing and presentation of endogenous antigen (GO:0019883)3.14764827
47regulation of antigen processing and presentation (GO:0002577)3.14312322
48cellular extravasation (GO:0045123)3.13977231
49regulation of mast cell degranulation (GO:0043304)3.13575483
50pyrimidine dimer repair (GO:0006290)3.12886679
51response to muramyl dipeptide (GO:0032495)3.12221814
52positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.12095451
53T cell migration (GO:0072678)3.10316694
54positive regulation of granulocyte differentiation (GO:0030854)3.09169292
55regulation of gamma-delta T cell activation (GO:0046643)3.08430178
56regulation of dendritic cell antigen processing and presentation (GO:0002604)3.06699604
57negative T cell selection (GO:0043383)3.00543303
58B cell homeostasis (GO:0001782)2.96589821
59regulation of telomere maintenance (GO:0032204)2.94556044
60Arp2/3 complex-mediated actin nucleation (GO:0034314)2.94150839
61response to protozoan (GO:0001562)2.93577109
62mast cell activation (GO:0045576)2.93076598
63energy homeostasis (GO:0097009)2.92121088
64tRNA methylation (GO:0030488)2.91710357
65Peyers patch development (GO:0048541)2.89589739
66mucosal-associated lymphoid tissue development (GO:0048537)2.89589739
67megakaryocyte development (GO:0035855)2.89157885
68interferon-gamma production (GO:0032609)2.87740003
69response to peptidoglycan (GO:0032494)2.85238973
70regulation of granulocyte differentiation (GO:0030852)2.84822983
71regulation of myeloid leukocyte mediated immunity (GO:0002886)2.84004005
72detection of molecule of bacterial origin (GO:0032490)2.82827678
73mature B cell differentiation (GO:0002335)2.82126061
74regulation of mast cell activation involved in immune response (GO:0033006)2.81647744
75negative regulation of interleukin-8 production (GO:0032717)2.79362279
76negative regulation of erythrocyte differentiation (GO:0045647)2.78983918
77antigen processing and presentation via MHC class Ib (GO:0002475)2.78917580
78T cell homeostasis (GO:0043029)2.76382362
79histone H3-K4 trimethylation (GO:0080182)2.75721799
80positive regulation of interferon-alpha production (GO:0032727)2.74617613
81detection of external biotic stimulus (GO:0098581)2.74044941
82cellular response to interleukin-15 (GO:0071350)2.73220683
83regulation of gamma-delta T cell differentiation (GO:0045586)2.73068375
84B cell receptor signaling pathway (GO:0050853)2.72779194
85immunoglobulin mediated immune response (GO:0016064)2.71575500
86thymic T cell selection (GO:0045061)2.70895137
87mature B cell differentiation involved in immune response (GO:0002313)2.70637514
88regulation of leukocyte degranulation (GO:0043300)2.70053890
89T cell selection (GO:0045058)2.69564033
90positive regulation of interleukin-1 beta secretion (GO:0050718)2.69554804
91response to interferon-beta (GO:0035456)2.67798566
92positive regulation of antigen processing and presentation (GO:0002579)2.67338944
93regulation of erythrocyte differentiation (GO:0045646)2.65287003
94mast cell activation involved in immune response (GO:0002279)2.62974023
95mast cell degranulation (GO:0043303)2.62974023
96poly(A)+ mRNA export from nucleus (GO:0016973)2.62299869
97regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.62187539
98G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.61736450
99regulation of triglyceride catabolic process (GO:0010896)2.61213912
100lymphocyte homeostasis (GO:0002260)2.60190432
101lymph node development (GO:0048535)2.57986698
102JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.57124293
103B cell mediated immunity (GO:0019724)2.56523616
104negative regulation of bone resorption (GO:0045779)2.56190512
105activation of MAPKKK activity (GO:0000185)2.55256530
106negative regulation of lymphocyte mediated immunity (GO:0002707)2.55145707
107regulation of interferon-alpha production (GO:0032647)2.52843604
108positive regulation of B cell activation (GO:0050871)2.52133591
109embryonic hemopoiesis (GO:0035162)2.52116455
110response to interleukin-15 (GO:0070672)2.51732747
111myeloid cell activation involved in immune response (GO:0002275)2.51261206
112neutrophil mediated immunity (GO:0002446)2.50794195
113regulation of MHC class II biosynthetic process (GO:0045346)2.50690764
114toxin transport (GO:1901998)2.50586613
115tolerance induction (GO:0002507)2.50471467
116response to type I interferon (GO:0034340)2.50406292
117negative regulation of interleukin-6 production (GO:0032715)2.50242440
118cellular response to exogenous dsRNA (GO:0071360)2.49382265
119positive T cell selection (GO:0043368)2.49131858
120hepatocyte apoptotic process (GO:0097284)2.48356655
121detection of biotic stimulus (GO:0009595)2.47901082
122positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.47555826
123myeloid dendritic cell activation (GO:0001773)2.47337935
124regulation of germinal center formation (GO:0002634)2.47322285
125modulation by virus of host process (GO:0019054)2.47024492
126pinocytosis (GO:0006907)2.46874794
127positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.46098949
128leukocyte homeostasis (GO:0001776)2.44986905
129neutrophil activation (GO:0042119)2.44750817
130negative regulation of innate immune response (GO:0045824)2.44269325
131negative regulation of leukocyte mediated immunity (GO:0002704)2.44238961
132type I interferon signaling pathway (GO:0060337)2.44222829
133cellular response to type I interferon (GO:0071357)2.44222829
134macrophage activation (GO:0042116)2.43665741
135positive regulation of interleukin-1 secretion (GO:0050716)2.43263657
136cellular response to interferon-beta (GO:0035458)2.43044817
137response to UV-B (GO:0010224)2.42636223
138cellular response to thyroid hormone stimulus (GO:0097067)2.42345431
139negative regulation of interleukin-12 production (GO:0032695)2.42103850
140negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.41944906
141peptide catabolic process (GO:0043171)2.39839856
142phagocytosis, engulfment (GO:0006911)2.39563346
143angiogenesis involved in wound healing (GO:0060055)2.39034327
144B cell activation involved in immune response (GO:0002312)2.37484248
145regulation of regulatory T cell differentiation (GO:0045589)2.37470114
146peptidyl-lysine trimethylation (GO:0018023)2.36733702
147positive regulation of interferon-beta production (GO:0032728)2.36559525
148interferon-gamma-mediated signaling pathway (GO:0060333)2.35771136
149positive regulation of interleukin-8 secretion (GO:2000484)2.34653132
150positive regulation of natural killer cell differentiation (GO:0032825)2.33563828
151leukocyte degranulation (GO:0043299)2.33373103
152negative regulation of telomere maintenance (GO:0032205)2.32715497
153actin nucleation (GO:0045010)2.32653245
154fucose catabolic process (GO:0019317)2.32160135
155L-fucose metabolic process (GO:0042354)2.32160135
156L-fucose catabolic process (GO:0042355)2.32160135
157negative regulation of viral genome replication (GO:0045071)2.31837618
158NIK/NF-kappaB signaling (GO:0038061)2.31428176
159positive regulation of lipoprotein lipase activity (GO:0051006)2.30966722
160positive regulation of triglyceride lipase activity (GO:0061365)2.30966722
161negative regulation of nitric oxide biosynthetic process (GO:0045019)2.30091301
162regulation of mast cell activation (GO:0033003)2.29664553
163positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.28837704
164regulation of hypersensitivity (GO:0002883)2.28357257
165positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.25838434
166negative regulation of T cell mediated immunity (GO:0002710)2.25752965

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.72242545
2SCL_19346495_ChIP-Seq_HPC-7_Human4.58701272
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.26679443
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.04186783
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.88899104
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.79020800
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.77752124
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.65354052
9ELF1_17652178_ChIP-ChIP_JURKAT_Human3.58819966
10IRF8_21731497_ChIP-ChIP_J774_Mouse3.54950327
11TP63_19390658_ChIP-ChIP_HaCaT_Human3.15881057
12SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.97279132
13NOTCH1_21737748_ChIP-Seq_TLL_Human2.94270051
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.89205466
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.74019395
16* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.72703250
17SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.71774276
18FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.47518472
19IRF8_27001747_Chip-Seq_BMDM_Mouse2.47494865
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.41977986
21RUNX_20019798_ChIP-Seq_JUKART_Human2.38918759
22* SPI1_23547873_ChIP-Seq_NB4_Human2.37305423
23LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.34229804
24IGF1R_20145208_ChIP-Seq_DFB_Human2.32099065
25STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.29779812
26VDR_21846776_ChIP-Seq_THP-1_Human2.29154597
27STAT4_19710469_ChIP-ChIP_TH1__Mouse2.20797793
28MYC_22102868_ChIP-Seq_BL_Human2.12889596
29KDM2B_26808549_Chip-Seq_SUP-B15_Human2.07279383
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.03856224
31MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.02865368
32GATA1_19941826_ChIP-Seq_K562_Human2.02279923
33NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.01695746
34FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.01157286
35TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.00209660
36SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.97505446
37KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.96988138
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.93453979
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.90883587
40PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.87709878
41LXR_22292898_ChIP-Seq_THP-1_Human1.86842745
42MYB_26560356_Chip-Seq_TH2_Human1.86448681
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.83008344
44LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.82589228
45ERG_20887958_ChIP-Seq_HPC-7_Mouse1.82187162
46VDR_24763502_ChIP-Seq_THP-1_Human1.81915138
47KDM2B_26808549_Chip-Seq_DND41_Human1.81523834
48CIITA_25753668_ChIP-Seq_RAJI_Human1.78972808
49RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.78324365
50RARG_19884340_ChIP-ChIP_MEFs_Mouse1.78250528
51GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.72420157
52* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.67310781
53TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.66247475
54RUNX1_22412390_ChIP-Seq_EML_Mouse1.66225598
55HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.64164596
56E2F4_17652178_ChIP-ChIP_JURKAT_Human1.63568619
57FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.63403877
58NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.62613239
59FOXM1_23109430_ChIP-Seq_U2OS_Human1.62496651
60RBPJ_22232070_ChIP-Seq_NCS_Mouse1.62071522
61MYB_26560356_Chip-Seq_TH1_Human1.61779577
62GATA1_22025678_ChIP-Seq_K562_Human1.58744387
63NCOR1_26117541_ChIP-Seq_K562_Human1.56824577
64RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.53512411
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.51778094
66KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.51470682
67TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.50615842
68ELF1_20517297_ChIP-Seq_JURKAT_Human1.46346757
69CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.45931611
70STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.44019945
71PU_27001747_Chip-Seq_BMDM_Mouse1.43393372
72BRD4_27068464_Chip-Seq_AML-cells_Mouse1.43115112
73GATA2_19941826_ChIP-Seq_K562_Human1.42395663
74VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39849213
75FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.39567813
76GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.38456662
77MAF_26560356_Chip-Seq_TH1_Human1.37208761
78TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.37002831
79PPARA_22158963_ChIP-Seq_LIVER_Mouse1.33964057
80UTX_26944678_Chip-Seq_JUKART_Human1.32220370
81THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.32198238
82ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.31195227
83SPI1_23127762_ChIP-Seq_K562_Human1.30236666
84TCF7_22412390_ChIP-Seq_EML_Mouse1.27828510
85RXR_22158963_ChIP-Seq_LIVER_Mouse1.27731853
86BCL6_27268052_Chip-Seq_Bcells_Human1.26115939
87CTCF_27219007_Chip-Seq_ERYTHROID_Human1.25723958
88GATA2_22383799_ChIP-Seq_G1ME_Mouse1.25496613
89GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.25479774
90VDR_24787735_ChIP-Seq_THP-1_Human1.25479158
91DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.24261928
92P68_20966046_ChIP-Seq_HELA_Human1.24107025
93BCOR_27268052_Chip-Seq_Bcells_Human1.23771937
94FOXP3_21729870_ChIP-Seq_TREG_Human1.20595204
95* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.17922682
96GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.17530891
97E2F1_21310950_ChIP-Seq_MCF-7_Human1.15183156
98SALL1_21062744_ChIP-ChIP_HESCs_Human1.13118092
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12292346
100* RACK7_27058665_Chip-Seq_MCF-7_Human1.11970045
101CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.11835890
102HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.10211577
103PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10056463
104KDM2B_26808549_Chip-Seq_JURKAT_Human1.09316114
105VDR_23849224_ChIP-Seq_CD4+_Human1.08625675
106GATA1_22383799_ChIP-Seq_G1ME_Mouse1.08237517
107SA1_27219007_Chip-Seq_ERYTHROID_Human1.07552836
108YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.07381462
109IKZF1_21737484_ChIP-ChIP_HCT116_Human1.06160016
110PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04859350
111CTCF_21964334_ChIP-Seq_BJAB-B_Human1.01731198
112STAT1_20625510_ChIP-Seq_HELA_Human1.00350899
113CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99978891
114SRF_21415370_ChIP-Seq_HL-1_Mouse0.99889743
115TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99185527
116SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.98884071
117VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.98484597
118STAT6_21828071_ChIP-Seq_BEAS2B_Human0.97362619
119CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97245610
120MYC_18555785_ChIP-Seq_MESCs_Mouse0.97178692
121PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96021780
122Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.95111009
123P300_27268052_Chip-Seq_Bcells_Human0.93941438
124PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93675682
125CTCF_26484167_Chip-Seq_Bcells_Mouse0.93051426
126NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92455468
127YY1_21170310_ChIP-Seq_MESCs_Mouse0.91968012
128E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.89231352
129HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.88230051
130GATA3_26560356_Chip-Seq_TH2_Human0.85533127
131GATA1_19941827_ChIP-Seq_MEL_Mouse0.83904569
132ELK1_19687146_ChIP-ChIP_HELA_Human0.83542400
133MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.82273931
134SMAD_19615063_ChIP-ChIP_OVARY_Human0.82261426
135PCGF2_27294783_Chip-Seq_ESCs_Mouse0.79818178
136PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.79448689
137GATA2_21666600_ChIP-Seq_HMVEC_Human0.77446537
138IRF1_19129219_ChIP-ChIP_H3396_Human0.76177172
139GATA3_27048872_Chip-Seq_THYMUS_Human0.74964150
140SUZ12_27294783_Chip-Seq_NPCs_Mouse0.73866210
141CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.70784550
142NFE2_27457419_Chip-Seq_LIVER_Mouse0.70440744
143EWS_26573619_Chip-Seq_HEK293_Human0.68171047
144MAF_26560356_Chip-Seq_TH2_Human0.67327379
145PCGF2_27294783_Chip-Seq_NPCs_Mouse0.66177421

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system4.15835703
2MP0001835_abnormal_antigen_presentation3.57896143
3MP0005671_abnormal_response_to3.08686635
4MP0005075_abnormal_melanosome_morpholog2.92558845
5MP0005058_abnormal_lysosome_morphology2.83050097
6MP0008058_abnormal_DNA_repair2.61318878
7MP0008007_abnormal_cellular_replicative2.58045613
8MP0000015_abnormal_ear_pigmentation2.57283326
9MP0003303_peritoneal_inflammation2.47558318
10MP0000569_abnormal_digit_pigmentation2.37719175
11MP0005464_abnormal_platelet_physiology2.29819913
12MP0003763_abnormal_thymus_physiology2.28220928
13MP0001800_abnormal_humoral_immune2.27405389
14MP0009785_altered_susceptibility_to2.26062662
15MP0003436_decreased_susceptibility_to2.18767722
16MP0005174_abnormal_tail_pigmentation2.18432364
17MP0002452_abnormal_antigen_presenting2.15272359
18MP0004808_abnormal_hematopoietic_stem2.12100431
19MP0003656_abnormal_erythrocyte_physiolo2.07560383
20MP0006292_abnormal_olfactory_placode2.05837488
21MP0003724_increased_susceptibility_to2.04932611
22MP0004947_skin_inflammation2.03186773
23MP0002419_abnormal_innate_immunity2.01282028
24MP0000465_gastrointestinal_hemorrhage2.00172181
25MP0002420_abnormal_adaptive_immunity1.98354438
26MP0000685_abnormal_immune_system1.98162424
27MP0001819_abnormal_immune_cell1.97911187
28MP0002723_abnormal_immune_serum1.97829626
29MP0002398_abnormal_bone_marrow1.96014473
30MP0009840_abnormal_foam_cell1.91454628
31MP0005000_abnormal_immune_tolerance1.91330254
32MP0001790_abnormal_immune_system1.85655806
33MP0005387_immune_system_phenotype1.85655806
34MP0002095_abnormal_skin_pigmentation1.85328289
35MP0005025_abnormal_response_to1.80037341
36MP0002166_altered_tumor_susceptibility1.76034704
37MP0002148_abnormal_hypersensitivity_rea1.74624494
38MP0000716_abnormal_immune_system1.70269118
39MP0000689_abnormal_spleen_morphology1.69214530
40MP0010094_abnormal_chromosome_stability1.67970462
41MP0002722_abnormal_immune_system1.58877044
42MP0003172_abnormal_lysosome_physiology1.57476153
43MP0001873_stomach_inflammation1.55662164
44MP0001188_hyperpigmentation1.55023454
45MP0003111_abnormal_nucleus_morphology1.50392564
46MP0001545_abnormal_hematopoietic_system1.48510505
47MP0005397_hematopoietic_system_phenotyp1.48510505
48MP0002429_abnormal_blood_cell1.45570452
49MP0000703_abnormal_thymus_morphology1.43141717
50MP0003279_aneurysm1.43001224
51MP0002006_tumorigenesis1.42180978
52MP0002138_abnormal_hepatobiliary_system1.37545266
53MP0010155_abnormal_intestine_physiology1.36909338
54MP0000490_abnormal_crypts_of1.35175200
55MP0010030_abnormal_orbit_morphology1.34708264
56MP0002405_respiratory_system_inflammati1.34040452
57MP0005360_urolithiasis1.33951338
58MP0002638_abnormal_pupillary_reflex1.29637460
59MP0005645_abnormal_hypothalamus_physiol1.26077158
60MP0003077_abnormal_cell_cycle1.25497012
61MP0000516_abnormal_urinary_system1.25008509
62MP0005367_renal/urinary_system_phenotyp1.25008509
63MP0001958_emphysema1.23807823
64MP0001845_abnormal_inflammatory_respons1.17242239
65MP0009278_abnormal_bone_marrow1.16549091
66MP0002139_abnormal_hepatobiliary_system1.15808977
67MP0005666_abnormal_adipose_tissue1.12654123
68MP0006082_CNS_inflammation1.10883250
69MP0003828_pulmonary_edema1.10677507
70MP0000371_diluted_coat_color1.10120750
71MP0004147_increased_porphyrin_level1.09625576
72MP0002102_abnormal_ear_morphology1.09501509
73MP0001853_heart_inflammation1.06633395
74MP0008057_abnormal_DNA_replication1.06440576
75MP0003300_gastrointestinal_ulcer1.06160901
76MP0002933_joint_inflammation1.02945536
77MP0000249_abnormal_blood_vessel1.02630628
78MP0002249_abnormal_larynx_morphology1.02585524
79MP0001533_abnormal_skeleton_physiology1.01752851
80MP0008004_abnormal_stomach_pH1.01386545
81MP0002928_abnormal_bile_duct0.99922090
82MP0000858_altered_metastatic_potential0.98673838
83MP0001986_abnormal_taste_sensitivity0.98475049
84MP0005164_abnormal_response_to0.98106219
85MP0009333_abnormal_splenocyte_physiolog0.97364496
86MP0009384_cardiac_valve_regurgitation0.97042187
87MP0005390_skeleton_phenotype0.96762722
88MP0001270_distended_abdomen0.96679879
89MP0009697_abnormal_copulation0.93825245
90MP0004130_abnormal_muscle_cell0.92845715
91MP0000343_altered_response_to0.92819230
92MP0002075_abnormal_coat/hair_pigmentati0.92690334
93MP0005083_abnormal_biliary_tract0.92563522
94MP0003690_abnormal_glial_cell0.90829452
95MP0005375_adipose_tissue_phenotype0.90377307
96MP0008469_abnormal_protein_level0.89749193
97MP0004381_abnormal_hair_follicle0.89625575
98MP0009764_decreased_sensitivity_to0.89244365
99MP0003943_abnormal_hepatobiliary_system0.88661133
100MP0002009_preneoplasia0.87849869
101MP0001186_pigmentation_phenotype0.87117761
102MP0003191_abnormal_cellular_cholesterol0.85698880
103MP0001851_eye_inflammation0.84031871
104MP0004883_abnormal_blood_vessel0.83226852
105MP0000049_abnormal_middle_ear0.82672508
106MP0005646_abnormal_pituitary_gland0.82101921
107MP0003866_abnormal_defecation0.81777868
108MP0003795_abnormal_bone_structure0.81629382
109MP0009643_abnormal_urine_homeostasis0.80359588
110MP0002019_abnormal_tumor_incidence0.79513172
111MP0005365_abnormal_bile_salt0.79450403
112MP0001663_abnormal_digestive_system0.78882641
113MP0010329_abnormal_lipoprotein_level0.78745321
114MP0005670_abnormal_white_adipose0.78379749
115MP0005535_abnormal_body_temperature0.77739188
116MP0004185_abnormal_adipocyte_glucose0.76839812
117MP0002998_abnormal_bone_remodeling0.76559342
118MP0000566_synostosis0.76309899
119MP0008260_abnormal_autophagy0.76108120
120MP0005584_abnormal_enzyme/coenzyme_acti0.75679959
121MP0000013_abnormal_adipose_tissue0.75506238
122MP0005310_abnormal_salivary_gland0.75146176
123MP0002938_white_spotting0.74754626
124MP0000609_abnormal_liver_physiology0.74297574
125MP0009765_abnormal_xenobiotic_induced0.74019134
126MP0005257_abnormal_intraocular_pressure0.73958218
127MP0003786_premature_aging0.73316406
128MP0001849_ear_inflammation0.73209595
129MP0003075_altered_response_to0.72959659
130MP0000313_abnormal_cell_death0.72184840
131MP0003183_abnormal_peptide_metabolism0.71981843
132MP0004134_abnormal_chest_morphology0.71822464
133MP0002277_abnormal_respiratory_mucosa0.70848975
134MP0002971_abnormal_brown_adipose0.70796602
135MP0005275_abnormal_skin_tensile0.70772433
136MP0002132_abnormal_respiratory_system0.69022095
137MP0006054_spinal_hemorrhage0.67957354
138MP0009763_increased_sensitivity_to0.67293616
139MP0002177_abnormal_outer_ear0.66714221

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)3.71532586
2Dysostosis multiplex (HP:0000943)3.70134218
3Urinary glycosaminoglycan excretion (HP:0003541)3.70003448
4Mucopolysacchariduria (HP:0008155)3.70003448
5Recurrent abscess formation (HP:0002722)3.62936717
6Abnormality of mucopolysaccharide metabolism (HP:0011020)3.59562513
7Abnormality of polysaccharide metabolism (HP:0011012)3.59562513
8Abnormality of glycosaminoglycan metabolism (HP:0004371)3.59562513
9Myositis (HP:0100614)3.59404359
10Abnormality of macrophages (HP:0004311)3.51482075
11Recurrent bacterial skin infections (HP:0005406)3.22513515
12Chromsome breakage (HP:0040012)3.10118757
13Chronic otitis media (HP:0000389)3.08622528
14Thrombocytosis (HP:0001894)3.07389699
15Colitis (HP:0002583)3.06233378
16Systemic lupus erythematosus (HP:0002725)3.04765749
17Abnormal delayed hypersensitivity skin test (HP:0002963)3.01547458
18Chromosomal breakage induced by crosslinking agents (HP:0003221)2.99280048
19Broad face (HP:0000283)2.98509745
20Optic neuritis (HP:0100653)2.96899718
21Retrobulbar optic neuritis (HP:0100654)2.96899718
22Reduced antithrombin III activity (HP:0001976)2.96799388
23Purpura (HP:0000979)2.92577077
24Interstitial pulmonary disease (HP:0006530)2.92446589
25Fatigue (HP:0012378)2.86313744
26Aplastic anemia (HP:0001915)2.83631798
27Orchitis (HP:0100796)2.80395514
28IgM deficiency (HP:0002850)2.80085607
29Abnormality of the fingertips (HP:0001211)2.78422801
30Abnormality of the prostate (HP:0008775)2.77259384
31Inflammation of the large intestine (HP:0002037)2.76754750
32Increased IgE level (HP:0003212)2.73811090
33Elevated erythrocyte sedimentation rate (HP:0003565)2.71756009
34Increased serum ferritin (HP:0003281)2.71744694
35Gastrointestinal inflammation (HP:0004386)2.70763297
36Tented upper lip vermilion (HP:0010804)2.64603871
37Myelodysplasia (HP:0002863)2.64339870
38Abnormality of iron homeostasis (HP:0011031)2.58849200
39Polycythemia (HP:0001901)2.56507969
40Recurrent gram-negative bacterial infections (HP:0005420)2.55614946
41Epistaxis (HP:0000421)2.53147397
42Abnormality of DNA repair (HP:0003254)2.51757204
43Complement deficiency (HP:0004431)2.46455977
44Spontaneous hematomas (HP:0007420)2.46007767
45Spinal cord lesions (HP:0100561)2.44343385
46Syringomyelia (HP:0003396)2.44343385
47Autoimmune thrombocytopenia (HP:0001973)2.44332553
48Meningitis (HP:0001287)2.44147467
49Recurrent fungal infections (HP:0002841)2.43824268
50Recurrent viral infections (HP:0004429)2.41500385
51Cervical subluxation (HP:0003308)2.40229095
52Retinal atrophy (HP:0001105)2.38125750
53Abnormality of complement system (HP:0005339)2.37967392
54Joint stiffness (HP:0001387)2.37115448
55Obstructive lung disease (HP:0006536)2.35317031
56Chronic obstructive pulmonary disease (HP:0006510)2.35317031
57Menorrhagia (HP:0000132)2.35028530
58Thickened calvaria (HP:0002684)2.33900238
59Panhypogammaglobulinemia (HP:0003139)2.31688243
60Broad alveolar ridges (HP:0000187)2.30862909
61Increased cerebral lipofuscin (HP:0011813)2.30289919
62Abnormality of liposaccharide metabolism (HP:0010968)2.29763577
63Abnormality of glycosphingolipid metabolism (HP:0004343)2.29763577
64Abnormality of glycolipid metabolism (HP:0010969)2.29763577
65Abnormal platelet volume (HP:0011876)2.29498269
66Agammaglobulinemia (HP:0004432)2.26565096
67Gingivitis (HP:0000230)2.26207963
68Type I transferrin isoform profile (HP:0003642)2.25320790
69Eczematoid dermatitis (HP:0000976)2.25188548
70J-shaped sella turcica (HP:0002680)2.23892333
71Hypergammaglobulinemia (HP:0010702)2.23702691
72Stomatitis (HP:0010280)2.19898738
73Hypertriglyceridemia (HP:0002155)2.18581147
74Recurrent skin infections (HP:0001581)2.17270971
75Hemoptysis (HP:0002105)2.15545903
76Acute myeloid leukemia (HP:0004808)2.15175365
77Abnormality of transition element cation homeostasis (HP:0011030)2.14320109
78Amyloidosis (HP:0011034)2.12851365
79Abnormality of the nasal septum (HP:0000419)2.11100285
80Reticulocytopenia (HP:0001896)2.09848650
81Osteomyelitis (HP:0002754)2.09687554
82Loss of speech (HP:0002371)2.09276572
83Increased neuronal autofluorescent lipopigment (HP:0002074)2.08364995
84Hypertensive crisis (HP:0100735)2.08025146
85Granulocytopenia (HP:0001913)2.07143494
86Chronic diarrhea (HP:0002028)2.06490839
87Urethral obstruction (HP:0000796)2.06391775
88Chest pain (HP:0100749)2.05215645
89Gastrointestinal infarctions (HP:0005244)2.04744710
90Abnormality of the intervertebral disk (HP:0005108)2.04371401
91Encephalitis (HP:0002383)2.03447912
92Hepatosplenomegaly (HP:0001433)2.03101425
93Hyperlipoproteinemia (HP:0010980)2.03082086
94Gingival bleeding (HP:0000225)2.02819575
95Amaurosis fugax (HP:0100576)2.02226737
96Abnormality of eosinophils (HP:0001879)1.99702034
97Impaired platelet aggregation (HP:0003540)1.99597874
98Abnormal platelet function (HP:0011869)1.99597874
99Spondylolisthesis (HP:0003302)1.99218017
100Arterial thrombosis (HP:0004420)1.98480288
101Birth length less than 3rd percentile (HP:0003561)1.97509432
102T lymphocytopenia (HP:0005403)1.96996546
103Aplasia/Hypoplasia of the uvula (HP:0010293)1.96945595
104Increased mean platelet volume (HP:0011877)1.96919803
105Chronic mucocutaneous candidiasis (HP:0002728)1.96660867
106Recurrent cutaneous fungal infections (HP:0011370)1.96660867
107Renal dysplasia (HP:0000110)1.96532009
108Mesangial abnormality (HP:0001966)1.95427623
109Abnormality of the metopic suture (HP:0005556)1.94975895
110Abnormality of T cell physiology (HP:0011840)1.94968002
111Emphysema (HP:0002097)1.94852609
112Pustule (HP:0200039)1.94618819
113Eosinophilia (HP:0001880)1.94239197
114Increased IgM level (HP:0003496)1.93969645
115Clubbing of toes (HP:0100760)1.93936514
116Vasculitis (HP:0002633)1.92314170
117Broad palm (HP:0001169)1.92008829
118Mediastinal lymphadenopathy (HP:0100721)1.91821288
119Hypergonadotropic hypogonadism (HP:0000815)1.91340043
120Aortic aneurysm (HP:0004942)1.90142553
121Abnormality of the nasal mucosa (HP:0000433)1.89728126
122Patchy hypopigmentation of hair (HP:0011365)1.88566922
123Cellulitis (HP:0100658)1.87640832
124Dislocated radial head (HP:0003083)1.86677933
125Pulmonary infiltrates (HP:0002113)1.84979814
126Gastrointestinal stroma tumor (HP:0100723)1.84195613
127White forelock (HP:0002211)1.83968955
128Abnormality of the heme biosynthetic pathway (HP:0010472)1.83958476
129Pulmonary embolism (HP:0002204)1.83845689
130Deep philtrum (HP:0002002)1.83775231
131Vacuolated lymphocytes (HP:0001922)1.82995907
132Prostate neoplasm (HP:0100787)1.82696723
133Thyroid-stimulating hormone excess (HP:0002925)1.82519691
134Abnormality of the columella (HP:0009929)1.82487767
135Bone marrow hypocellularity (HP:0005528)1.81961269
136Thyroiditis (HP:0100646)1.81699548
137Morphological abnormality of the middle ear (HP:0008609)1.80936010
138Leukocytosis (HP:0001974)1.80147404
139Abnormality of the renal cortex (HP:0011035)1.80084082
140Keratitis (HP:0000491)1.79943836
141Prominent metopic ridge (HP:0005487)1.79077004
142Bruising susceptibility (HP:0000978)1.77442837
143Petechiae (HP:0000967)1.76453277
144Periodontitis (HP:0000704)1.75317113
145Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.74212676
146Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.72423441
147Abnormality of B cell number (HP:0010975)1.72075837
148B lymphocytopenia (HP:0010976)1.72075837
149IgG deficiency (HP:0004315)1.71826988
150Abnormality of the pleura (HP:0002103)1.71615539
151Abnormality of T cells (HP:0002843)1.71323699
152Agnosia (HP:0010524)1.69930240
153Albinism (HP:0001022)1.69635959
154Abnormality of the distal phalanges of the toes (HP:0010182)1.69109770
155Abnormality of the radial head (HP:0003995)1.68723467
156Cheilitis (HP:0100825)1.68182988
157Hypothermia (HP:0002045)1.67889438
158Decreased skull ossification (HP:0004331)1.66940237

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK43.19602160
2ERN13.06345082
3TGFBR23.04965260
4TXK2.88256286
5MAP4K12.73572694
6KIT2.73047368
7TRIB32.37304271
8MAP2K32.34210355
9STK162.33302097
10TGFBR12.13639628
11PIK3CG2.10419976
12ADRBK22.06439926
13TAOK22.04538357
14IRAK42.04122317
15BTK1.99761594
16BLK1.97828222
17CDK81.93057910
18GRK61.92880523
19CSF1R1.87923886
20TEC1.84234747
21MAP3K131.80125239
22ICK1.75055554
23IKBKE1.73941920
24YES11.70128486
25MAP3K141.67209639
26MKNK21.63644040
27MKNK11.52662198
28MAP3K61.45631891
29PIM21.41397189
30IKBKB1.41162132
31MAPK71.39606445
32ZAP701.37017750
33TYK21.35572362
34BMPR1B1.34296154
35IRAK31.31658659
36SGK21.31094695
37GRK71.28859053
38VRK11.28095346
39SIK31.25438134
40FGFR31.24866237
41MAP2K21.23174890
42FLT31.23159075
43ERBB31.21799427
44MAP3K71.19549951
45EEF2K1.19048149
46SYK1.17955301
47ZAK1.17661141
48MAP3K31.15786544
49EIF2AK21.14186777
50RPS6KA41.13890690
51HIPK21.13324148
52MAPK111.13244616
53SIK11.11255229
54CAMK1D1.10587029
55JAK31.07665380
56LYN1.06381954
57TBK11.05640103
58CDC42BPA1.02436239
59SRPK11.02351660
60MARK21.02222397
61BRD41.01657388
62RPS6KA61.01649987
63BMPR21.00616757
64HCK0.98381659
65MAP3K10.97397708
66CDK70.96151476
67RPS6KC10.95645041
68RPS6KL10.95645041
69LCK0.93530622
70CAMK1G0.91736944
71PIM10.91060878
72CHUK0.89334304
73JAK20.88930221
74MAPK120.88261066
75ATR0.88214182
76TNIK0.88202436
77ITK0.86189128
78TESK20.86016298
79TNK20.85905550
80EPHB10.85296572
81PRKD20.85039151
82MAP3K20.84065642
83SIK20.83623823
84BMX0.81622598
85PLK40.81158366
86KSR20.80494112
87RIPK10.80353912
88SMG10.79782198
89SGK30.78744932
90MYLK0.77354228
91NLK0.76446806
92PTK2B0.74632817
93FES0.73939267
94FGFR40.73047564
95RET0.72037126
96TRPM70.70595721
97JAK10.69401999
98AKT30.67667524
99EPHA30.66400230
100TAOK30.65654901
101MAP2K60.64913449
102PDPK10.64716519
103MAPK130.64695002
104DYRK30.64622437
105PDK10.59420490
106PTK60.58394894
107TTN0.57231056
108CDC70.57003391
109CAMK40.56218413
110BRSK20.56060559
111PKN20.56004706
112MATK0.55332594
113CDK30.55181229
114CDK40.53133375
115PRPF4B0.52368343
116LRRK20.52256109
117MARK30.51803270
118STK100.51522056
119PAK40.50342572
120RPS6KA50.50337004
121PRKAA20.49972597
122RPS6KA20.49813981
123CLK10.47289641
124MAPKAPK30.45736684
125MAPK150.45606199
126PRKD10.45472863
127CDK90.43184653
128RPS6KB20.42654853
129MTOR0.42481982
130KDR0.41611362
131PDGFRB0.41440885
132CDK60.41276097
133MAPKAPK20.41088239
134MAPK30.40971881
135STK40.39226514
136CDK120.38950447
137WEE10.38752235
138MAPK40.38671268
139TAOK10.37721224
140CSK0.37307281
141PIK3CA0.37243939
142NEK20.36711527
143GSK3A0.36176700

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.66681160
2DNA replication_Homo sapiens_hsa030302.51125419
3Homologous recombination_Homo sapiens_hsa034402.34754366
4Base excision repair_Homo sapiens_hsa034102.34091692
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.33220933
6Glycosaminoglycan degradation_Homo sapiens_hsa005312.31257948
7Measles_Homo sapiens_hsa051622.18634420
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.14019223
9Non-homologous end-joining_Homo sapiens_hsa034502.12275038
10Mismatch repair_Homo sapiens_hsa034302.10560703
11Leishmaniasis_Homo sapiens_hsa051402.08489604
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.06013937
13Fanconi anemia pathway_Homo sapiens_hsa034602.00254642
14Toll-like receptor signaling pathway_Homo sapiens_hsa046201.98198359
15RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.92783945
16B cell receptor signaling pathway_Homo sapiens_hsa046621.90465958
17Osteoclast differentiation_Homo sapiens_hsa043801.78048328
18Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.75891943
19Hematopoietic cell lineage_Homo sapiens_hsa046401.73594641
20Herpes simplex infection_Homo sapiens_hsa051681.71684222
21Transcriptional misregulation in cancer_Homo sapiens_hsa052021.71598574
22Intestinal immune network for IgA production_Homo sapiens_hsa046721.68570882
23Other glycan degradation_Homo sapiens_hsa005111.66841836
24Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.49502211
25Influenza A_Homo sapiens_hsa051641.48305621
26Nucleotide excision repair_Homo sapiens_hsa034201.48017594
27Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.43100267
28Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.42522801
29Allograft rejection_Homo sapiens_hsa053301.40746768
30Staphylococcus aureus infection_Homo sapiens_hsa051501.36288796
31Acute myeloid leukemia_Homo sapiens_hsa052211.35881535
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.35692602
33Type I diabetes mellitus_Homo sapiens_hsa049401.30247626
34Hepatitis B_Homo sapiens_hsa051611.29860787
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.25195545
36Notch signaling pathway_Homo sapiens_hsa043301.24441647
37Toxoplasmosis_Homo sapiens_hsa051451.23373848
38Chronic myeloid leukemia_Homo sapiens_hsa052201.19992027
39RNA polymerase_Homo sapiens_hsa030201.15562841
40Spliceosome_Homo sapiens_hsa030401.13498585
41Antigen processing and presentation_Homo sapiens_hsa046121.13336160
42T cell receptor signaling pathway_Homo sapiens_hsa046601.11918711
43Cell cycle_Homo sapiens_hsa041101.11868681
44Ribosome_Homo sapiens_hsa030101.11725597
45Pyrimidine metabolism_Homo sapiens_hsa002401.08643737
46Legionellosis_Homo sapiens_hsa051341.08141096
47Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.07921634
48Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.06686519
49Malaria_Homo sapiens_hsa051441.02547593
50TNF signaling pathway_Homo sapiens_hsa046681.02056220
51Pancreatic cancer_Homo sapiens_hsa052121.01145554
52Apoptosis_Homo sapiens_hsa042101.01118781
53Pertussis_Homo sapiens_hsa051331.00744588
54Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.99753911
55RNA degradation_Homo sapiens_hsa030180.97609324
56Complement and coagulation cascades_Homo sapiens_hsa046100.95637588
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.91981717
58Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90771156
59VEGF signaling pathway_Homo sapiens_hsa043700.89601894
60Colorectal cancer_Homo sapiens_hsa052100.89390641
61Adipocytokine signaling pathway_Homo sapiens_hsa049200.88958646
62Shigellosis_Homo sapiens_hsa051310.88082914
63Platelet activation_Homo sapiens_hsa046110.86158838
64HTLV-I infection_Homo sapiens_hsa051660.83626232
65Glycerophospholipid metabolism_Homo sapiens_hsa005640.83556831
66Rheumatoid arthritis_Homo sapiens_hsa053230.82574152
67Chemokine signaling pathway_Homo sapiens_hsa040620.81875383
68Lysine degradation_Homo sapiens_hsa003100.79088670
69SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79075955
70Amoebiasis_Homo sapiens_hsa051460.77728247
71Epstein-Barr virus infection_Homo sapiens_hsa051690.76727672
72Arachidonic acid metabolism_Homo sapiens_hsa005900.76248908
73Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.75623384
74Insulin resistance_Homo sapiens_hsa049310.75354642
75p53 signaling pathway_Homo sapiens_hsa041150.75288251
76Cyanoamino acid metabolism_Homo sapiens_hsa004600.75109220
77Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.73752241
78Small cell lung cancer_Homo sapiens_hsa052220.72641780
79Graft-versus-host disease_Homo sapiens_hsa053320.72581003
80Tuberculosis_Homo sapiens_hsa051520.72492383
81Autoimmune thyroid disease_Homo sapiens_hsa053200.72401060
82Choline metabolism in cancer_Homo sapiens_hsa052310.68414623
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.66767621
84mTOR signaling pathway_Homo sapiens_hsa041500.63603239
85Carbohydrate digestion and absorption_Homo sapiens_hsa049730.61372732
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.60197571
87Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.59555802
88One carbon pool by folate_Homo sapiens_hsa006700.59045943
89Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58714262
90ABC transporters_Homo sapiens_hsa020100.58336062
91Asthma_Homo sapiens_hsa053100.58130433
92Viral myocarditis_Homo sapiens_hsa054160.56241474
93GnRH signaling pathway_Homo sapiens_hsa049120.56182166
94Basal transcription factors_Homo sapiens_hsa030220.55287302
95Leukocyte transendothelial migration_Homo sapiens_hsa046700.54888851
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54488803
97Salmonella infection_Homo sapiens_hsa051320.54150328
98Linoleic acid metabolism_Homo sapiens_hsa005910.54130155
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.52759550
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.51818878
101Inositol phosphate metabolism_Homo sapiens_hsa005620.51548114
102Prolactin signaling pathway_Homo sapiens_hsa049170.51296869
103Hepatitis C_Homo sapiens_hsa051600.51005546
104mRNA surveillance pathway_Homo sapiens_hsa030150.50718929
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.50351961
106Dorso-ventral axis formation_Homo sapiens_hsa043200.50103328
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.49764479
108Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48793824
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48503069
110Non-small cell lung cancer_Homo sapiens_hsa052230.47974738
111Caffeine metabolism_Homo sapiens_hsa002320.47641766
112Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47584707
113Purine metabolism_Homo sapiens_hsa002300.46643681
114MicroRNAs in cancer_Homo sapiens_hsa052060.46285171
115alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46005023
116Phagosome_Homo sapiens_hsa041450.45858030
117PPAR signaling pathway_Homo sapiens_hsa033200.43658770
118Focal adhesion_Homo sapiens_hsa045100.41828532
119Chemical carcinogenesis_Homo sapiens_hsa052040.41464677
120N-Glycan biosynthesis_Homo sapiens_hsa005100.41038980
121Fructose and mannose metabolism_Homo sapiens_hsa000510.41002644
122Lysosome_Homo sapiens_hsa041420.40972738
123Pathways in cancer_Homo sapiens_hsa052000.40713776
124Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40702955
125Renal cell carcinoma_Homo sapiens_hsa052110.40614053
126Longevity regulating pathway - mammal_Homo sapiens_hsa042110.39902336
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39719867
128FoxO signaling pathway_Homo sapiens_hsa040680.39694478
129African trypanosomiasis_Homo sapiens_hsa051430.39104011
130Glycerolipid metabolism_Homo sapiens_hsa005610.38721269
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.37066530
132Systemic lupus erythematosus_Homo sapiens_hsa053220.35769965
133Viral carcinogenesis_Homo sapiens_hsa052030.35514282

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