ACBD6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)8.40788455
2viral transcription (GO:0019083)6.89111238
3translational termination (GO:0006415)6.66677203
4ribosomal small subunit assembly (GO:0000028)6.56335828
5ribosomal small subunit biogenesis (GO:0042274)6.29728519
6translational elongation (GO:0006414)5.90460850
7ribosomal large subunit biogenesis (GO:0042273)5.54054192
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.45593831
9cellular protein complex disassembly (GO:0043624)5.41224720
10cotranslational protein targeting to membrane (GO:0006613)5.33238276
11protein targeting to ER (GO:0045047)5.31653894
12maturation of SSU-rRNA (GO:0030490)5.28379755
13nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.17012468
14viral life cycle (GO:0019058)5.13994515
15establishment of protein localization to endoplasmic reticulum (GO:0072599)5.06614633
16translational initiation (GO:0006413)5.04792855
17protein localization to endoplasmic reticulum (GO:0070972)5.00490205
18protein complex disassembly (GO:0043241)4.96856496
19macromolecular complex disassembly (GO:0032984)4.75128738
20sperm motility (GO:0030317)4.57735187
21acrosome reaction (GO:0007340)4.51132778
22sperm-egg recognition (GO:0035036)4.44892307
23binding of sperm to zona pellucida (GO:0007339)4.43123604
24fusion of sperm to egg plasma membrane (GO:0007342)4.41474997
25ribonucleoprotein complex biogenesis (GO:0022613)4.38709439
26motile cilium assembly (GO:0044458)4.29429163
27deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.14303903
28cilium or flagellum-dependent cell motility (GO:0001539)4.06373398
29axonemal dynein complex assembly (GO:0070286)4.05678351
30cell wall macromolecule metabolic process (GO:0044036)4.03141246
31cell wall macromolecule catabolic process (GO:0016998)4.03141246
32translation (GO:0006412)3.99533574
33epithelial cilium movement (GO:0003351)3.94852189
34regulation of cilium movement (GO:0003352)3.86535231
35cell-cell recognition (GO:0009988)3.85185953
36chaperone-mediated protein transport (GO:0072321)3.82501473
37spermatid development (GO:0007286)3.80003176
38DNA replication checkpoint (GO:0000076)3.75748681
39cellular component biogenesis (GO:0044085)3.70624790
40nuclear-transcribed mRNA catabolic process (GO:0000956)3.65019524
41GTP biosynthetic process (GO:0006183)3.64201662
42telomere maintenance via semi-conservative replication (GO:0032201)3.60150721
43DNA strand elongation involved in DNA replication (GO:0006271)3.59117094
44piRNA metabolic process (GO:0034587)3.57443562
45spliceosomal snRNP assembly (GO:0000387)3.57262561
46rRNA processing (GO:0006364)3.56098359
47rRNA metabolic process (GO:0016072)3.53560156
48plasma membrane fusion (GO:0045026)3.52750623
49protein targeting to membrane (GO:0006612)3.51852162
50UTP biosynthetic process (GO:0006228)3.47073301
51mRNA catabolic process (GO:0006402)3.46797343
52chromatin remodeling at centromere (GO:0031055)3.45444316
53regulation of mitochondrial translation (GO:0070129)3.43639570
54DNA strand elongation (GO:0022616)3.38810166
55pseudouridine synthesis (GO:0001522)3.38671787
56establishment of protein localization to mitochondrial membrane (GO:0090151)3.35760317
57microtubule depolymerization (GO:0007019)3.34814202
58proteasome assembly (GO:0043248)3.34740278
59RNA catabolic process (GO:0006401)3.34495033
60ribosome biogenesis (GO:0042254)3.33105473
61kinetochore organization (GO:0051383)3.31128694
62kinetochore assembly (GO:0051382)3.30666301
63ncRNA 3-end processing (GO:0043628)3.28701027
64male meiosis I (GO:0007141)3.27865954
65CENP-A containing nucleosome assembly (GO:0034080)3.27564906
66male meiosis (GO:0007140)3.26501056
67termination of RNA polymerase III transcription (GO:0006386)3.26257973
68transcription elongation from RNA polymerase III promoter (GO:0006385)3.26257973
69guanosine-containing compound biosynthetic process (GO:1901070)3.25285652
70establishment of integrated proviral latency (GO:0075713)3.23749297
71base-excision repair, AP site formation (GO:0006285)3.16323724
72epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.16172494
73mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.14727938
74acrosome assembly (GO:0001675)3.12126992
75synaptonemal complex assembly (GO:0007130)3.10671666
76synaptonemal complex organization (GO:0070193)3.10661028
77multicellular organism reproduction (GO:0032504)3.09692843
78pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.09417030
79spliceosomal complex assembly (GO:0000245)3.06385881
80DNA replication initiation (GO:0006270)3.04460079
81mitotic recombination (GO:0006312)3.03596412
82meiosis I (GO:0007127)3.03004253
83pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.01474949
84peptidyl-histidine modification (GO:0018202)3.00506903
85cilium movement (GO:0003341)2.98250292
86CTP metabolic process (GO:0046036)2.97557195
87CTP biosynthetic process (GO:0006241)2.97557195
88pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.97462649
89negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.97328369
90formation of translation preinitiation complex (GO:0001731)2.95249514
91L-serine metabolic process (GO:0006563)2.95160554
92tRNA methylation (GO:0030488)2.94915145
93respiratory electron transport chain (GO:0022904)2.94741600
94UTP metabolic process (GO:0046051)2.94415172
95mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.94265341
96mitochondrial respiratory chain complex I assembly (GO:0032981)2.94265341
97NADH dehydrogenase complex assembly (GO:0010257)2.94265341
98negative regulation of RNA splicing (GO:0033119)2.94222325
99regulation of mitotic spindle checkpoint (GO:1903504)2.92760783
100regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.92760783
101telomere maintenance via recombination (GO:0000722)2.92548403
102DNA methylation involved in gamete generation (GO:0043046)2.91464946
103pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.89439361
104RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.88666784
105tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.88666784
106pteridine-containing compound biosynthetic process (GO:0042559)2.87644026
107electron transport chain (GO:0022900)2.87403679
108transcription-coupled nucleotide-excision repair (GO:0006283)2.87115038
109DNA replication-independent nucleosome assembly (GO:0006336)2.86236274
110DNA replication-independent nucleosome organization (GO:0034724)2.86236274
111protein targeting to mitochondrion (GO:0006626)2.85215565
112histone H2A acetylation (GO:0043968)2.84426386
113peptidyl-arginine omega-N-methylation (GO:0035247)2.81149601
114rRNA modification (GO:0000154)2.78597349
115nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.77768083
116protein complex biogenesis (GO:0070271)2.77560807
117mitochondrial respiratory chain complex assembly (GO:0033108)2.76456066
118pyrimidine nucleotide catabolic process (GO:0006244)2.75113691
119regulation of translational fidelity (GO:0006450)2.74072641
120exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.73953697
121histone arginine methylation (GO:0034969)2.72933450
122negative regulation of mRNA processing (GO:0050686)2.71899170
123resolution of meiotic recombination intermediates (GO:0000712)2.71402788
124tRNA aminoacylation for protein translation (GO:0006418)2.71227243
125ncRNA metabolic process (GO:0034660)2.70790637
126pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.70746677
127histone exchange (GO:0043486)2.69860611
128replication fork processing (GO:0031297)2.69136316
129tRNA aminoacylation (GO:0043039)2.68947099
130amino acid activation (GO:0043038)2.68947099
131establishment of protein localization to mitochondrion (GO:0072655)2.68926500
132ribonucleoprotein complex disassembly (GO:0032988)2.68811764
133mitotic sister chromatid segregation (GO:0000070)2.68238744
134ncRNA processing (GO:0034470)2.67255124
135iron-sulfur cluster assembly (GO:0016226)2.65948719
136metallo-sulfur cluster assembly (GO:0031163)2.65948719
137telomere maintenance via telomere lengthening (GO:0010833)2.65626423
138nucleotide-excision repair, DNA gap filling (GO:0006297)2.65614835
139tRNA processing (GO:0008033)2.65575079
140DNA damage response, detection of DNA damage (GO:0042769)2.65295539
141tRNA metabolic process (GO:0006399)2.64072508
142DNA unwinding involved in DNA replication (GO:0006268)2.63650866
143base-excision repair (GO:0006284)2.63331124
144mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.62931271
145ATP synthesis coupled proton transport (GO:0015986)2.62907879
146energy coupled proton transport, down electrochemical gradient (GO:0015985)2.62907879
147protein localization to mitochondrion (GO:0070585)2.61750206
148tRNA modification (GO:0006400)2.61113131
149establishment of viral latency (GO:0019043)2.61076448

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.54734314
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.47373493
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.23616003
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.94515101
5E2F7_22180533_ChIP-Seq_HELA_Human3.26121870
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.20777561
7MYC_18358816_ChIP-ChIP_MESCs_Mouse3.18980621
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.06549859
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.99698407
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.86240478
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.69190779
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.64811471
13XRN2_22483619_ChIP-Seq_HELA_Human2.56126445
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.52034972
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.47913101
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.46240449
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.33687850
18YY1_21170310_ChIP-Seq_MESCs_Mouse2.30671936
19* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.27989307
20ELK1_19687146_ChIP-ChIP_HELA_Human2.21012255
21TTF2_22483619_ChIP-Seq_HELA_Human2.19497895
22EZH2_22144423_ChIP-Seq_EOC_Human2.18147773
23SRY_22984422_ChIP-ChIP_TESTIS_Rat2.14482215
24DCP1A_22483619_ChIP-Seq_HELA_Human2.13051900
25THAP11_20581084_ChIP-Seq_MESCs_Mouse2.08220040
26* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.08121375
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.06182313
28* E2F4_17652178_ChIP-ChIP_JURKAT_Human1.99912702
29VDR_23849224_ChIP-Seq_CD4+_Human1.98382559
30CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.98011214
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.96579982
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.95831308
33* FOXP3_21729870_ChIP-Seq_TREG_Human1.95328009
34CREB1_15753290_ChIP-ChIP_HEK293T_Human1.93732902
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.90701640
36PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.89320415
37ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.86596269
38GABP_19822575_ChIP-Seq_HepG2_Human1.82217038
39RBPJ_22232070_ChIP-Seq_NCS_Mouse1.78709399
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.74817057
41CTCF_18555785_ChIP-Seq_MESCs_Mouse1.72865350
42NOTCH1_21737748_ChIP-Seq_TLL_Human1.71938010
43* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.69593629
44TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60809342
45CIITA_25753668_ChIP-Seq_RAJI_Human1.59893500
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58542846
47CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.54758244
48PADI4_21655091_ChIP-ChIP_MCF-7_Human1.54609974
49POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.49521727
50* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.49371460
51SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.49349026
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.48830713
53KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.47627908
54* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.47587497
55FOXM1_23109430_ChIP-Seq_U2OS_Human1.44693874
56YY1_22570637_ChIP-Seq_MALME-3M_Human1.42312325
57TET1_21451524_ChIP-Seq_MESCs_Mouse1.39187637
58CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.38339129
59CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.37212963
60DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.36048806
61MYC_18940864_ChIP-ChIP_HL60_Human1.35940774
62MYC_22102868_ChIP-Seq_BL_Human1.34615866
63SOX2_16153702_ChIP-ChIP_HESCs_Human1.32419719
64* SRF_21415370_ChIP-Seq_HL-1_Mouse1.30532727
65* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.28022270
66MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.27300204
67* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.26676584
68* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26088862
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25366416
70EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.24848525
71POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.24280357
72ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22807627
73FOXP1_21924763_ChIP-Seq_HESCs_Human1.21320662
74SOX2_18555785_ChIP-Seq_MESCs_Mouse1.20910605
75NELFA_20434984_ChIP-Seq_ESCs_Mouse1.20678839
76RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.19769591
77STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.14306091
78VDR_21846776_ChIP-Seq_THP-1_Human1.07637358
79CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.06619514
80ZNF274_21170338_ChIP-Seq_K562_Hela1.06300203
81* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.06130919
82ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05899842
83* KDM5A_27292631_Chip-Seq_BREAST_Human1.05302987
84PHF8_20622854_ChIP-Seq_HELA_Human1.04912162
85ELF1_20517297_ChIP-Seq_JURKAT_Human1.04502478
86TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04036447
87SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.03582281
88BCL6_27268052_Chip-Seq_Bcells_Human1.01240302
89SCL_19346495_ChIP-Seq_HPC-7_Human1.00712262
90DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00485258
91CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99010351
92PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97318397
93EWS_26573619_Chip-Seq_HEK293_Human0.97083285
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.95991314
95STAT1_20625510_ChIP-Seq_HELA_Human0.95870081
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.95699658
97CTCF_26484167_Chip-Seq_Bcells_Mouse0.93703976
98YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.93587962
99NANOG_16153702_ChIP-ChIP_HESCs_Human0.93374218
100RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93372073
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.92132543
102E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.91877572
103KLF4_18555785_ChIP-Seq_MESCs_Mouse0.91033106
104SA1_27219007_Chip-Seq_ERYTHROID_Human0.90816194
105TP63_19390658_ChIP-ChIP_HaCaT_Human0.89157487
106ELK1_22589737_ChIP-Seq_MCF10A_Human0.89070903
107POU5F1_16153702_ChIP-ChIP_HESCs_Human0.88670433
108GATA1_26923725_Chip-Seq_HPCs_Mouse0.88443137
109MAF_26560356_Chip-Seq_TH2_Human0.88131743
110* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.87298642
111KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.87047978
112NANOG_18555785_ChIP-Seq_MESCs_Mouse0.86922421
113PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.86339991
114ZNF263_19887448_ChIP-Seq_K562_Human0.86274789
115P68_20966046_ChIP-Seq_HELA_Human0.85825424
116* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.85677746
117* E2F1_21310950_ChIP-Seq_MCF-7_Human0.85453142
118CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.84179818
119ESR1_15608294_ChIP-ChIP_MCF-7_Human0.83717642
120CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.83457387
121CTCF_20526341_ChIP-Seq_ESCs_Human0.83324479
122* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.83293552
123E2F1_20622854_ChIP-Seq_HELA_Human0.82173510
124* IRF1_19129219_ChIP-ChIP_H3396_Human0.81674590
125IGF1R_20145208_ChIP-Seq_DFB_Human0.80864578
126POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.80481633
127TBX5_21415370_ChIP-Seq_HL-1_Mouse0.79537255
128ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.79106910

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization5.68164844
2MP0009379_abnormal_foot_pigmentation3.89716458
3MP0003693_abnormal_embryo_hatching3.56392913
4MP0003111_abnormal_nucleus_morphology2.96750730
5MP0003698_abnormal_male_reproductive2.79797053
6MP0001929_abnormal_gametogenesis2.64715664
7MP0010094_abnormal_chromosome_stability2.59352054
8MP0008877_abnormal_DNA_methylation2.57158997
9MP0002653_abnormal_ependyma_morphology2.50706514
10MP0008058_abnormal_DNA_repair2.50415937
11MP0006292_abnormal_olfactory_placode2.43315295
12MP0001188_hyperpigmentation2.27514509
13MP0004957_abnormal_blastocyst_morpholog2.25845346
14MP0002210_abnormal_sex_determination2.23481004
15MP0003077_abnormal_cell_cycle2.02760458
16MP0002938_white_spotting1.95336179
17MP0002102_abnormal_ear_morphology1.92922697
18MP0001145_abnormal_male_reproductive1.88715225
19MP0001529_abnormal_vocalization1.86786876
20MP0008995_early_reproductive_senescence1.82508106
21MP0003121_genomic_imprinting1.81083536
22MP0003786_premature_aging1.70826375
23MP0002160_abnormal_reproductive_system1.68861655
24MP0002396_abnormal_hematopoietic_system1.66934777
25MP0000653_abnormal_sex_gland1.61175751
26MP0005174_abnormal_tail_pigmentation1.57251489
27MP0002132_abnormal_respiratory_system1.56987625
28MP0003123_paternal_imprinting1.56864342
29MP0002161_abnormal_fertility/fecundity1.56142147
30MP0008932_abnormal_embryonic_tissue1.56139981
31MP0001968_abnormal_touch/_nociception1.50875947
32MP0006276_abnormal_autonomic_nervous1.49614085
33MP0008007_abnormal_cellular_replicative1.49465088
34MP0010030_abnormal_orbit_morphology1.49288546
35MP0005075_abnormal_melanosome_morpholog1.48796110
36MP0005397_hematopoietic_system_phenotyp1.43742073
37MP0001545_abnormal_hematopoietic_system1.43742073
38MP0000778_abnormal_nervous_system1.43725927
39MP0003646_muscle_fatigue1.41419595
40MP0000372_irregular_coat_pigmentation1.40578567
41MP0003136_yellow_coat_color1.40454917
42MP0001984_abnormal_olfaction1.40144691
43MP0008057_abnormal_DNA_replication1.40034642
44MP0002163_abnormal_gland_morphology1.39655645
45MP0000490_abnormal_crypts_of1.38697154
46MP0003122_maternal_imprinting1.37851466
47MP0002736_abnormal_nociception_after1.37669292
48MP0003879_abnormal_hair_cell1.36035345
49MP0000678_abnormal_parathyroid_gland1.35604535
50MP0006036_abnormal_mitochondrial_physio1.28630650
51MP0003567_abnormal_fetal_cardiomyocyte1.26633651
52MP0002638_abnormal_pupillary_reflex1.26278355
53MP0006035_abnormal_mitochondrial_morpho1.24508512
54MP0000015_abnormal_ear_pigmentation1.24052187
55MP0003011_delayed_dark_adaptation1.23188950
56MP0004808_abnormal_hematopoietic_stem1.22333942
57MP0002095_abnormal_skin_pigmentation1.21458011
58MP0003937_abnormal_limbs/digits/tail_de1.20878203
59MP0003186_abnormal_redox_activity1.20535144
60MP0002234_abnormal_pharynx_morphology1.19701390
61MP0008789_abnormal_olfactory_epithelium1.17180115
62MP0003806_abnormal_nucleotide_metabolis1.16985149
63MP0003880_abnormal_central_pattern1.14858283
64MP0003718_maternal_effect1.11175945
65MP0003941_abnormal_skin_development1.10639619
66MP0000313_abnormal_cell_death1.09645432
67MP0003890_abnormal_embryonic-extraembry1.09124952
68MP0000049_abnormal_middle_ear1.08626988
69MP0005394_taste/olfaction_phenotype1.08303931
70MP0005499_abnormal_olfactory_system1.08303931
71MP0002822_catalepsy1.08153368
72MP0003861_abnormal_nervous_system1.08034026
73MP0002085_abnormal_embryonic_tissue1.05505844
74MP0001286_abnormal_eye_development1.04651394
75MP0003385_abnormal_body_wall1.03083830
76MP0002751_abnormal_autonomic_nervous1.02270993
77MP0000358_abnormal_cell_content/1.02228797
78MP0000703_abnormal_thymus_morphology1.02091114
79MP0002084_abnormal_developmental_patter1.01401336
80MP0002697_abnormal_eye_size1.00959797
81MP0002177_abnormal_outer_ear0.98372243
82MP0004147_increased_porphyrin_level0.96942886
83MP0003755_abnormal_palate_morphology0.96639702
84MP0000631_abnormal_neuroendocrine_gland0.95974779
85MP0002233_abnormal_nose_morphology0.95295038
86MP0001986_abnormal_taste_sensitivity0.95127034
87MP0005389_reproductive_system_phenotype0.95018623
88MP0004859_abnormal_synaptic_plasticity0.94037233
89MP0001672_abnormal_embryogenesis/_devel0.94034910
90MP0005380_embryogenesis_phenotype0.94034910
91MP0002249_abnormal_larynx_morphology0.94027610
92MP0009697_abnormal_copulation0.93943945
93MP0003763_abnormal_thymus_physiology0.93479227
94MP0004197_abnormal_fetal_growth/weight/0.91420572
95MP0003878_abnormal_ear_physiology0.91275177
96MP0005377_hearing/vestibular/ear_phenot0.91275177
97MP0009333_abnormal_splenocyte_physiolog0.91195200
98MP0002752_abnormal_somatic_nervous0.89408904
99MP0003315_abnormal_perineum_morphology0.89300892
100MP0005391_vision/eye_phenotype0.89110801
101MP0003635_abnormal_synaptic_transmissio0.87061503
102MP0000955_abnormal_spinal_cord0.85959891
103MP0002111_abnormal_tail_morphology0.84997172
104MP0005253_abnormal_eye_physiology0.84336757
105MP0005084_abnormal_gallbladder_morpholo0.84104457
106MP0002184_abnormal_innervation0.84040694
107MP0003984_embryonic_growth_retardation0.83340555
108MP0001293_anophthalmia0.83183471
109MP0002092_abnormal_eye_morphology0.82938396
110MP0006072_abnormal_retinal_apoptosis0.80995225
111MP0003787_abnormal_imprinting0.80721356
112MP0002088_abnormal_embryonic_growth/wei0.79901190
113MP0008872_abnormal_physiological_respon0.79842164
114MP0004233_abnormal_muscle_weight0.77526341
115MP0001270_distended_abdomen0.76750652
116MP0003656_abnormal_erythrocyte_physiolo0.76394658
117MP0009672_abnormal_birth_weight0.75887742
118MP0004142_abnormal_muscle_tone0.75630057
119MP0005646_abnormal_pituitary_gland0.75100474
120MP0005379_endocrine/exocrine_gland_phen0.73667172
121MP0001485_abnormal_pinna_reflex0.73647249
122MP0000350_abnormal_cell_proliferation0.73515091
123MP0008260_abnormal_autophagy0.72399684
124MP0002557_abnormal_social/conspecific_i0.71997777
125MP0002019_abnormal_tumor_incidence0.71766997
126MP0003938_abnormal_ear_development0.71335686
127MP0004133_heterotaxia0.71200394
128MP0003942_abnormal_urinary_system0.70882472
129MP0002152_abnormal_brain_morphology0.70498819
130MP0004145_abnormal_muscle_electrophysio0.70003460
131MP0005423_abnormal_somatic_nervous0.69760950
132MP0002398_abnormal_bone_marrow0.69329727
133MP0002080_prenatal_lethality0.69253500
134MP0001730_embryonic_growth_arrest0.68480041
135MP0005670_abnormal_white_adipose0.68317505
136MP0008770_decreased_survivor_rate0.67546905
137MP0001348_abnormal_lacrimal_gland0.66658873
138MP0003119_abnormal_digestive_system0.66463944
139MP0001697_abnormal_embryo_size0.66238225
140MP0002272_abnormal_nervous_system0.65658563
141MP0004381_abnormal_hair_follicle0.60861741

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.70153086
2Abnormal number of erythroid precursors (HP:0012131)6.48823492
3Absent/shortened dynein arms (HP:0200106)6.43357317
4Dynein arm defect of respiratory motile cilia (HP:0012255)6.43357317
5Reticulocytopenia (HP:0001896)5.33133034
6Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.30789122
7Abnormal respiratory motile cilium morphology (HP:0005938)4.78271281
8Abnormal respiratory epithelium morphology (HP:0012253)4.78271281
9Pallor (HP:0000980)4.71241715
10Decreased activity of mitochondrial respiratory chain (HP:0008972)4.36428765
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.36428765
12Macrocytic anemia (HP:0001972)4.23115503
13Abnormality of the heme biosynthetic pathway (HP:0010472)3.92764624
14Abnormal respiratory motile cilium physiology (HP:0012261)3.87386350
15Birth length less than 3rd percentile (HP:0003561)3.73160907
16Abnormal ciliary motility (HP:0012262)3.35897224
17Nasal polyposis (HP:0100582)3.31089282
18Cerebral edema (HP:0002181)3.01862006
19Acute necrotizing encephalopathy (HP:0006965)3.01387841
20Rhinitis (HP:0012384)2.93531544
21Microvesicular hepatic steatosis (HP:0001414)2.93268431
22Absent thumb (HP:0009777)2.90684766
23Abnormal mitochondria in muscle tissue (HP:0008316)2.87708897
24Mitochondrial inheritance (HP:0001427)2.86132429
25Abnormality of the preputium (HP:0100587)2.71594921
26Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.71566734
27Colon cancer (HP:0003003)2.69429946
28Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.69085426
29Abnormality of the labia minora (HP:0012880)2.56422136
30Abnormality of the nasal mucosa (HP:0000433)2.55437631
31Infertility (HP:0000789)2.55193027
32Hepatocellular necrosis (HP:0001404)2.54745889
33Abnormality of reticulocytes (HP:0004312)2.53057304
34Increased hepatocellular lipid droplets (HP:0006565)2.51010001
35Increased intramyocellular lipid droplets (HP:0012240)2.50583089
36Chronic bronchitis (HP:0004469)2.49827505
37Increased CSF lactate (HP:0002490)2.46342052
38Cortical dysplasia (HP:0002539)2.44780102
39Triphalangeal thumb (HP:0001199)2.44228936
40Aplasia/Hypoplasia of the sacrum (HP:0008517)2.43224672
41Increased serum lactate (HP:0002151)2.40969178
42Aplasia/Hypoplasia of the uvula (HP:0010293)2.38390889
43Absent rod-and cone-mediated responses on ERG (HP:0007688)2.36021123
44Progressive macrocephaly (HP:0004481)2.33237093
45Meckel diverticulum (HP:0002245)2.32240655
46Muscle fiber atrophy (HP:0100295)2.30041458
47Carpal bone hypoplasia (HP:0001498)2.26986937
48Type I transferrin isoform profile (HP:0003642)2.26280455
49Severe visual impairment (HP:0001141)2.25723723
50Nephronophthisis (HP:0000090)2.23814620
51Abnormality of the ileum (HP:0001549)2.23380193
52Chromosomal breakage induced by crosslinking agents (HP:0003221)2.22504709
53Aplastic anemia (HP:0001915)2.19944136
54Type 2 muscle fiber atrophy (HP:0003554)2.15854648
55Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.15685929
56Abnormality of alanine metabolism (HP:0010916)2.15685929
57Hyperalaninemia (HP:0003348)2.15685929
58Acute encephalopathy (HP:0006846)2.15581800
59Chromsome breakage (HP:0040012)2.14352051
60Abnormal delayed hypersensitivity skin test (HP:0002963)2.14264713
61Lactic acidosis (HP:0003128)2.13251051
62Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.12851774
63Abnormal protein N-linked glycosylation (HP:0012347)2.12851774
64Abnormal protein glycosylation (HP:0012346)2.12851774
65Abnormal glycosylation (HP:0012345)2.12851774
6611 pairs of ribs (HP:0000878)2.09257877
673-Methylglutaconic aciduria (HP:0003535)2.09193074
68Hyperglycinemia (HP:0002154)2.08509578
69Exertional dyspnea (HP:0002875)2.08238355
70Thrombocytosis (HP:0001894)2.07424113
71Bronchitis (HP:0012387)2.05948478
72Respiratory failure (HP:0002878)2.05549615
73Cerebral hypomyelination (HP:0006808)2.03832052
74Lipid accumulation in hepatocytes (HP:0006561)2.03003159
75Rib fusion (HP:0000902)2.01532169
76Septo-optic dysplasia (HP:0100842)2.01509266
77Patellar aplasia (HP:0006443)2.00758815
78Petechiae (HP:0000967)2.00625979
79Exercise intolerance (HP:0003546)1.99243599
80Medial flaring of the eyebrow (HP:0010747)1.99049184
81Increased muscle lipid content (HP:0009058)1.96495182
82Abnormality of DNA repair (HP:0003254)1.95797259
83Pancreatic fibrosis (HP:0100732)1.93452545
84Cerebellar dysplasia (HP:0007033)1.92765843
85Aplasia/Hypoplasia of the patella (HP:0006498)1.92250304
86Small intestinal stenosis (HP:0012848)1.91717413
87Duodenal stenosis (HP:0100867)1.91717413
88Retinal dysplasia (HP:0007973)1.91573735
89Abnormality of chromosome stability (HP:0003220)1.90813684
90Optic disc pallor (HP:0000543)1.90512910
91Hepatic necrosis (HP:0002605)1.90302438
92Progressive muscle weakness (HP:0003323)1.90279007
93Microretrognathia (HP:0000308)1.87201468
94Horseshoe kidney (HP:0000085)1.86351176
95Renal Fanconi syndrome (HP:0001994)1.85111243
96Molar tooth sign on MRI (HP:0002419)1.85024222
97Abnormality of midbrain morphology (HP:0002418)1.85024222
98Abnormal spermatogenesis (HP:0008669)1.84756691
99Myelodysplasia (HP:0002863)1.84209310
100Sclerocornea (HP:0000647)1.83541115
101Abnormal number of incisors (HP:0011064)1.83035401
102Abnormality of cochlea (HP:0000375)1.82799921
103Stenosis of the external auditory canal (HP:0000402)1.81943038
104Sloping forehead (HP:0000340)1.81856883
105Poor suck (HP:0002033)1.81811599
106Oral leukoplakia (HP:0002745)1.81470944
107Reduced antithrombin III activity (HP:0001976)1.80978095
108Unsteady gait (HP:0002317)1.79135901
109Hypoplastic pelvis (HP:0008839)1.78816322
110Upper limb muscle weakness (HP:0003484)1.78591869
111Nephrogenic diabetes insipidus (HP:0009806)1.78404465
112Abnormality of the metopic suture (HP:0005556)1.78002960
113Ragged-red muscle fibers (HP:0003200)1.77462529
114Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.76979591
115Recurrent bronchitis (HP:0002837)1.76695794
116Congenital primary aphakia (HP:0007707)1.76458057
117Delusions (HP:0000746)1.76373156
118Leukodystrophy (HP:0002415)1.76044106
119Cleft eyelid (HP:0000625)1.75953807
120Preaxial hand polydactyly (HP:0001177)1.74106438
121High anterior hairline (HP:0009890)1.74018807
122Bronchiectasis (HP:0002110)1.73725801
123Long foot (HP:0001833)1.73080719
124Hypoplasia of the pons (HP:0012110)1.72208044
125Depressed nasal ridge (HP:0000457)1.71969879
126Gait imbalance (HP:0002141)1.71902378
127Optic nerve coloboma (HP:0000588)1.71754070
128Prominent metopic ridge (HP:0005487)1.71240844
129Squamous cell carcinoma (HP:0002860)1.70865802
130Lissencephaly (HP:0001339)1.70722690
131Type II lissencephaly (HP:0007260)1.70510793
132Emotional lability (HP:0000712)1.69569986
133Facial cleft (HP:0002006)1.69440878
134Median cleft lip (HP:0000161)1.68520425
135Pancreatic cysts (HP:0001737)1.67864685
136Pancytopenia (HP:0001876)1.66446968
137Abnormal lung lobation (HP:0002101)1.65399229
138Lethargy (HP:0001254)1.64751299
139Concave nail (HP:0001598)1.63412046
140Respiratory difficulties (HP:0002880)1.62419544
141Poikiloderma (HP:0001029)1.62365849
142Bifid tongue (HP:0010297)1.62285664
143Ependymoma (HP:0002888)1.62208186
144Abnormality of glycolysis (HP:0004366)1.61063072
145Abnormality of the renal collecting system (HP:0004742)1.60792423
146Abnormality of the carotid arteries (HP:0005344)1.60524419
147Ectopic kidney (HP:0000086)1.57932967
148Absent septum pellucidum (HP:0001331)1.53949764
149Increased serum pyruvate (HP:0003542)1.53800001
150Anophthalmia (HP:0000528)1.53483234
151X-linked dominant inheritance (HP:0001423)1.53264219

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.16321426
2NME23.58475619
3TLK13.20002490
4PDK32.88449381
5PDK42.88449381
6CDK192.77534774
7BUB12.76713910
8VRK22.73352065
9ZAK2.61411128
10EEF2K2.38797145
11NEK22.31874781
12WEE12.23019776
13TESK12.21159044
14MAP3K112.04349848
15DYRK32.00511049
16DYRK21.97746176
17NME11.96652592
18NEK11.92510651
19MAP3K41.84763228
20PIM21.81540410
21TAOK21.79750023
22PBK1.76214812
23EIF2AK11.76193205
24CCNB11.67104940
25VRK11.67103329
26ICK1.63397105
27MAP4K21.62681570
28BRAF1.59387392
29SIK31.59385572
30CSNK1G31.56146143
31BMPR1B1.52526243
32MKNK21.48152847
33CSNK1G21.46029617
34MAP3K121.45428395
35PDK21.42586702
36WNK31.41628057
37CDK81.41591751
38CSNK1A1L1.40578072
39CSNK1G11.40288042
40SRPK11.38352025
41CDC71.33719772
42AURKA1.32616751
43TNIK1.30968115
44PLK31.28671304
45TNK21.28572310
46PRKD31.28301435
47MAPKAPK31.28162717
48BLK1.25327407
49PIK3CA1.25173538
50ARAF1.24755201
51PLK11.17474167
52NUAK11.17448725
53TAOK11.17028296
54RPS6KB21.16459010
55BCKDK1.13480584
56BCR1.12219193
57MAP2K71.09871274
58PNCK1.09747067
59MAP4K11.07920011
60CHEK21.05920146
61MAP2K41.04357370
62TESK21.03849405
63EIF2AK31.03182705
64MKNK11.01054799
65FLT30.97426793
66PINK10.96452259
67TRIM280.95595786
68RPS6KA40.94039904
69MUSK0.93831459
70ATM0.93053289
71ILK0.92959758
72CDK70.92167787
73MAP2K60.91863319
74BRSK10.88606024
75PASK0.87233158
76DAPK30.86602440
77ATR0.85759546
78SIK20.83505858
79MARK20.81924417
80CAMK10.79034826
81DAPK10.75257508
82PLK40.75097912
83TAF10.71291491
84CDK10.69976898
85PAK10.67021850
86TTK0.64954718
87CSNK2A20.64447714
88CSNK1E0.64019639
89BRSK20.62172466
90NTRK30.59928618
91MAP3K60.59302044
92SCYL20.58334463
93CDK40.56449846
94PRKDC0.55440792
95CDK140.55201719
96CSNK2A10.54738197
97KDR0.53807833
98AURKB0.53389227
99PRKCI0.51768719
100ADRBK20.51005415
101CDK30.50913078
102UHMK10.47311667
103MARK30.46928370
104CASK0.46405329
105RAF10.45356744
106RPS6KA50.44219181
107PTK20.43324481
108AKT20.42578027
109RPS6KA10.42261689
110CLK10.40995523
111MAPKAPK50.40559312
112CAMK1G0.40474469
113CHEK10.40376086
114PRKCG0.39657991
115MAP3K50.39045522
116MINK10.38439272
117BTK0.38046614
118MARK10.38019136
119PAK40.37659709
120CDK20.37326385
121EIF2AK20.37157527
122PKN20.36873153
123CDK180.36025115
124CDK150.35821703
125CAMK1D0.35404554
126LATS20.35088334
127CSNK1D0.34783695
128TSSK60.34465500
129NTRK20.33735767
130MAP3K100.33355284
131CSNK1A10.32365129
132DYRK1B0.32339232
133RPS6KA20.32266412
134FES0.32027338
135RPS6KL10.31740650
136RPS6KC10.31740650
137MAPK130.31291278
138CDK11A0.31239908
139IRAK10.29251044
140PTK2B0.29183392
141PDK10.28499509

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.28440658
2DNA replication_Homo sapiens_hsa030304.07980529
3Mismatch repair_Homo sapiens_hsa034303.15499922
4RNA polymerase_Homo sapiens_hsa030203.13784988
5Homologous recombination_Homo sapiens_hsa034402.94106952
6Proteasome_Homo sapiens_hsa030502.86417475
7Pyrimidine metabolism_Homo sapiens_hsa002402.78274231
8Spliceosome_Homo sapiens_hsa030402.61855686
9Oxidative phosphorylation_Homo sapiens_hsa001902.61427699
10Parkinsons disease_Homo sapiens_hsa050122.55000709
11Fanconi anemia pathway_Homo sapiens_hsa034602.49360755
12Nucleotide excision repair_Homo sapiens_hsa034202.36680737
13Sulfur relay system_Homo sapiens_hsa041222.36025829
14Huntingtons disease_Homo sapiens_hsa050162.34188799
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.32273944
16Base excision repair_Homo sapiens_hsa034102.30587284
17RNA transport_Homo sapiens_hsa030132.00926481
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.86606257
19Purine metabolism_Homo sapiens_hsa002301.78245497
20Alzheimers disease_Homo sapiens_hsa050101.74025344
21Basal transcription factors_Homo sapiens_hsa030221.71684788
22Cardiac muscle contraction_Homo sapiens_hsa042601.47027023
23RNA degradation_Homo sapiens_hsa030181.41239335
24Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.40457811
25Pentose phosphate pathway_Homo sapiens_hsa000301.39503806
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.38764052
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.38668749
28Cell cycle_Homo sapiens_hsa041101.30659535
29One carbon pool by folate_Homo sapiens_hsa006701.20890306
30Folate biosynthesis_Homo sapiens_hsa007901.19177360
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.16862861
32mRNA surveillance pathway_Homo sapiens_hsa030151.13289327
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.11575577
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11025458
35Steroid biosynthesis_Homo sapiens_hsa001001.00773546
36Cyanoamino acid metabolism_Homo sapiens_hsa004600.99198895
37Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.95494346
38Oocyte meiosis_Homo sapiens_hsa041140.95488915
39Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.93492636
40Protein export_Homo sapiens_hsa030600.93431321
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.91477773
42Propanoate metabolism_Homo sapiens_hsa006400.86349847
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.84502264
44Fatty acid elongation_Homo sapiens_hsa000620.83803432
45Cysteine and methionine metabolism_Homo sapiens_hsa002700.82964711
46Nicotine addiction_Homo sapiens_hsa050330.78875329
47Synaptic vesicle cycle_Homo sapiens_hsa047210.76603216
48Epstein-Barr virus infection_Homo sapiens_hsa051690.75071546
49p53 signaling pathway_Homo sapiens_hsa041150.73414798
50Butanoate metabolism_Homo sapiens_hsa006500.73275135
51Alcoholism_Homo sapiens_hsa050340.71598013
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68466271
53Lysine degradation_Homo sapiens_hsa003100.62416536
54Systemic lupus erythematosus_Homo sapiens_hsa053220.62000684
55Taste transduction_Homo sapiens_hsa047420.61299466
56Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.61233343
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60740766
58Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.59085758
59Non-homologous end-joining_Homo sapiens_hsa034500.58734191
60Olfactory transduction_Homo sapiens_hsa047400.56324523
61Basal cell carcinoma_Homo sapiens_hsa052170.55205305
62Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54355958
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.52178276
64Vitamin B6 metabolism_Homo sapiens_hsa007500.51790281
65Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.50768421
66Amphetamine addiction_Homo sapiens_hsa050310.50304264
67Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.49540180
68Fructose and mannose metabolism_Homo sapiens_hsa000510.49468535
69Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.48797428
70Regulation of autophagy_Homo sapiens_hsa041400.46122476
71Metabolic pathways_Homo sapiens_hsa011000.45682048
72Phototransduction_Homo sapiens_hsa047440.44754583
73Hippo signaling pathway_Homo sapiens_hsa043900.44647428
74Glucagon signaling pathway_Homo sapiens_hsa049220.44335220
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.44228819
76N-Glycan biosynthesis_Homo sapiens_hsa005100.43876158
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43751259
78Glutathione metabolism_Homo sapiens_hsa004800.43610374
79Biosynthesis of amino acids_Homo sapiens_hsa012300.43154238
80Hedgehog signaling pathway_Homo sapiens_hsa043400.42769716
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39695562
82Linoleic acid metabolism_Homo sapiens_hsa005910.38181321
83Antigen processing and presentation_Homo sapiens_hsa046120.36881881
84Herpes simplex infection_Homo sapiens_hsa051680.36123935
85Calcium signaling pathway_Homo sapiens_hsa040200.35054956
86Long-term potentiation_Homo sapiens_hsa047200.34993178
87Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.32532166
88Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.31412132
89Selenocompound metabolism_Homo sapiens_hsa004500.30868988
90HTLV-I infection_Homo sapiens_hsa051660.30785066
91Morphine addiction_Homo sapiens_hsa050320.30509014
92Acute myeloid leukemia_Homo sapiens_hsa052210.30080475
93Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.29290640
94Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29225383
95Circadian entrainment_Homo sapiens_hsa047130.28222863
96Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.27542547
97Pyruvate metabolism_Homo sapiens_hsa006200.27403015
98Melanoma_Homo sapiens_hsa052180.26934075
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25898764
100Carbon metabolism_Homo sapiens_hsa012000.25640331
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25410262
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.25008111
103Peroxisome_Homo sapiens_hsa041460.24886199
104Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.24478474
105Drug metabolism - other enzymes_Homo sapiens_hsa009830.23783346
106Wnt signaling pathway_Homo sapiens_hsa043100.22315622
107Collecting duct acid secretion_Homo sapiens_hsa049660.21757442
108Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.21333509
109Caffeine metabolism_Homo sapiens_hsa002320.21274406
110Colorectal cancer_Homo sapiens_hsa052100.20496991
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.19045482
112Viral carcinogenesis_Homo sapiens_hsa052030.18955372
113Serotonergic synapse_Homo sapiens_hsa047260.18674373
114Fatty acid metabolism_Homo sapiens_hsa012120.17731272
115Vibrio cholerae infection_Homo sapiens_hsa051100.17483416
116Primary immunodeficiency_Homo sapiens_hsa053400.17224723
117Dopaminergic synapse_Homo sapiens_hsa047280.16754830
118Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.15829341
119beta-Alanine metabolism_Homo sapiens_hsa004100.15450138
120Thyroid cancer_Homo sapiens_hsa052160.14502875
121Insulin secretion_Homo sapiens_hsa049110.13948539
122Axon guidance_Homo sapiens_hsa043600.13527372
123Cocaine addiction_Homo sapiens_hsa050300.13385161
124Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.13092629
125Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.12605110
126Glutamatergic synapse_Homo sapiens_hsa047240.11974128
127Oxytocin signaling pathway_Homo sapiens_hsa049210.10598826
128VEGF signaling pathway_Homo sapiens_hsa043700.10230262
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.09809691
130Central carbon metabolism in cancer_Homo sapiens_hsa052300.09652772
131Tryptophan metabolism_Homo sapiens_hsa003800.08678416
132Cholinergic synapse_Homo sapiens_hsa047250.08497483
133B cell receptor signaling pathway_Homo sapiens_hsa046620.08442086
134Galactose metabolism_Homo sapiens_hsa000520.06682591
135Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.06193517
136GABAergic synapse_Homo sapiens_hsa047270.03850216

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