AAMDC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)9.49521866
2central nervous system myelination (GO:0022010)9.49521866
3fatty acid elongation (GO:0030497)7.14789220
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.92988137
5myelination (GO:0042552)5.37759264
6ensheathment of neurons (GO:0007272)5.37062865
7axon ensheathment (GO:0008366)5.37062865
8mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.36272423
9energy coupled proton transport, down electrochemical gradient (GO:0015985)5.20277953
10ATP synthesis coupled proton transport (GO:0015986)5.20277953
11long-chain fatty acid biosynthetic process (GO:0042759)5.15819422
12respiratory electron transport chain (GO:0022904)4.92842479
13electron transport chain (GO:0022900)4.79226671
14cholesterol biosynthetic process (GO:0006695)4.72814723
15behavioral response to nicotine (GO:0035095)4.59491558
16negative regulation of protein localization to cell surface (GO:2000009)4.47610322
17creatine metabolic process (GO:0006600)4.46627228
18establishment of protein localization to mitochondrial membrane (GO:0090151)4.41175637
19negative regulation of neurotransmitter transport (GO:0051589)4.19129151
20sterol biosynthetic process (GO:0016126)4.15167715
21protein neddylation (GO:0045116)4.07467889
22chaperone-mediated protein transport (GO:0072321)4.02374956
23substantia nigra development (GO:0021762)4.01899232
24platelet dense granule organization (GO:0060155)3.94761030
25respiratory chain complex IV assembly (GO:0008535)3.87684685
26myelin maintenance (GO:0043217)3.83884786
27establishment of mitochondrion localization (GO:0051654)3.83099254
28response to methylmercury (GO:0051597)3.74417755
29isoprenoid biosynthetic process (GO:0008299)3.71177932
30oligodendrocyte differentiation (GO:0048709)3.69481253
31ubiquinone biosynthetic process (GO:0006744)3.67853554
32negative regulation of neurotransmitter secretion (GO:0046929)3.67843799
33mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.60297239
34mitochondrial respiratory chain complex I assembly (GO:0032981)3.60297239
35NADH dehydrogenase complex assembly (GO:0010257)3.60297239
36cytochrome complex assembly (GO:0017004)3.60122677
37regulation of lipoprotein metabolic process (GO:0050746)3.56939365
38long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.54586608
39response to redox state (GO:0051775)3.53105853
40long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.49708680
41protein-cofactor linkage (GO:0018065)3.48765174
42regulation of collateral sprouting (GO:0048670)3.46696439
43GPI anchor biosynthetic process (GO:0006506)3.43923378
44amyloid precursor protein metabolic process (GO:0042982)3.43752037
45epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.43579124
46presynaptic membrane organization (GO:0097090)3.41487383
47eye photoreceptor cell differentiation (GO:0001754)3.41016702
48photoreceptor cell differentiation (GO:0046530)3.41016702
49fatty-acyl-CoA metabolic process (GO:0035337)3.40939654
50detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.40623000
51ubiquinone metabolic process (GO:0006743)3.36604167
52water-soluble vitamin biosynthetic process (GO:0042364)3.36370909
53glycerophospholipid catabolic process (GO:0046475)3.36221056
54DNA deamination (GO:0045006)3.36101940
55epithelial cilium movement (GO:0003351)3.30487188
56protein complex biogenesis (GO:0070271)3.30288178
57proteasome assembly (GO:0043248)3.25823858
58tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.25638097
59RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.25638097
60presynaptic membrane assembly (GO:0097105)3.23604571
61positive regulation of oligodendrocyte differentiation (GO:0048714)3.22927368
62astrocyte development (GO:0014002)3.16324935
63GPI anchor metabolic process (GO:0006505)3.14872268
64apical protein localization (GO:0045176)3.13991691
65fatty-acyl-CoA biosynthetic process (GO:0046949)3.13595345
66nucleotide transmembrane transport (GO:1901679)3.09454787
67intracellular protein transmembrane import (GO:0044743)3.09391835
68regulation of skeletal muscle contraction (GO:0014819)3.08712498
69very long-chain fatty acid metabolic process (GO:0000038)3.07318115
70regulation of cilium movement (GO:0003352)3.04216487
71regulation of glucokinase activity (GO:0033131)2.99994629
72regulation of hexokinase activity (GO:1903299)2.99994629
73response to epinephrine (GO:0071871)2.99475655
74quinone biosynthetic process (GO:1901663)2.95990024
75neurotransmitter uptake (GO:0001504)2.95962019
76cellular response to epinephrine stimulus (GO:0071872)2.95961581
77positive regulation of cellular amine metabolic process (GO:0033240)2.94712178
78acyl-CoA biosynthetic process (GO:0071616)2.94091023
79thioester biosynthetic process (GO:0035384)2.94091023
80limb bud formation (GO:0060174)2.92760468
81hydrogen ion transmembrane transport (GO:1902600)2.92487082
82mitochondrial respiratory chain complex assembly (GO:0033108)2.88926705
83peptidyl-histidine modification (GO:0018202)2.87840718
84neuron cell-cell adhesion (GO:0007158)2.87749625
85positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.85854894
86L-amino acid import (GO:0043092)2.84602389
87asymmetric protein localization (GO:0008105)2.84230298
88positive regulation of action potential (GO:0045760)2.83949523
89L-fucose catabolic process (GO:0042355)2.83695115
90fucose catabolic process (GO:0019317)2.83695115
91L-fucose metabolic process (GO:0042354)2.83695115
92ketone body metabolic process (GO:1902224)2.81253916
93pseudouridine synthesis (GO:0001522)2.81222608
94nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.81201649
95preassembly of GPI anchor in ER membrane (GO:0016254)2.79853979
96indole-containing compound catabolic process (GO:0042436)2.79722793
97indolalkylamine catabolic process (GO:0046218)2.79722793
98tryptophan catabolic process (GO:0006569)2.79722793
99regulation of mitochondrial translation (GO:0070129)2.79565916
100proton transport (GO:0015992)2.79153177
101cellular ketone body metabolic process (GO:0046950)2.78376184
102magnesium ion transport (GO:0015693)2.77713203
103negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.75514500
104mannosylation (GO:0097502)2.74863953
105amino acid salvage (GO:0043102)2.74814236
106L-methionine salvage (GO:0071267)2.74814236
107L-methionine biosynthetic process (GO:0071265)2.74814236
108hydrogen transport (GO:0006818)2.74451034
109ATP biosynthetic process (GO:0006754)2.72865001
110neuron remodeling (GO:0016322)2.71474975
111transcription elongation from RNA polymerase III promoter (GO:0006385)2.71435992
112termination of RNA polymerase III transcription (GO:0006386)2.71435992
113import into cell (GO:0098657)2.71308974
114regulation of catecholamine metabolic process (GO:0042069)2.70402130
115regulation of dopamine metabolic process (GO:0042053)2.70402130
116neural nucleus development (GO:0048857)2.69518627
117neuronal action potential propagation (GO:0019227)2.68074429
118kynurenine metabolic process (GO:0070189)2.66565208
119peripheral nervous system axon ensheathment (GO:0032292)2.66396829
120myelination in peripheral nervous system (GO:0022011)2.66396829
121L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.64634003
122actin-myosin filament sliding (GO:0033275)2.64617551
123muscle filament sliding (GO:0030049)2.64617551
124viral transcription (GO:0019083)2.64328531
125cullin deneddylation (GO:0010388)2.64309333
126axon development (GO:0061564)2.64285962
127otic vesicle formation (GO:0030916)2.64138773
128exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.63717638
129translational termination (GO:0006415)2.62452605
130indolalkylamine metabolic process (GO:0006586)2.61963311
131negative regulation of telomere maintenance (GO:0032205)2.61165686
132membrane tubulation (GO:0097320)2.59955287
133somite development (GO:0061053)2.59925454
134negative regulation of execution phase of apoptosis (GO:1900118)2.58767049
135inner mitochondrial membrane organization (GO:0007007)2.58743498
136synaptic transmission, cholinergic (GO:0007271)2.56744509
137intraciliary transport (GO:0042073)2.55767832
138cornea development in camera-type eye (GO:0061303)2.54216109
139iron coordination entity transport (GO:1901678)2.53951141
140negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.52100618
141cilium movement (GO:0003341)2.52058074
142heme transport (GO:0015886)2.50396815
143cilium morphogenesis (GO:0060271)2.50210992
144purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.49540078
145ribonucleoside triphosphate biosynthetic process (GO:0009201)2.48722337
146peptidyl-cysteine modification (GO:0018198)2.48608213
147acyl-CoA metabolic process (GO:0006637)2.48121375
148thioester metabolic process (GO:0035383)2.48121375
149axoneme assembly (GO:0035082)2.46990844
150tryptophan metabolic process (GO:0006568)2.46453327
151purine nucleoside triphosphate biosynthetic process (GO:0009145)2.46049795
152SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.45470582
153cotranslational protein targeting to membrane (GO:0006613)2.45404583
154GTP biosynthetic process (GO:0006183)2.44787078
155negative regulation of JUN kinase activity (GO:0043508)2.44413651
156intracellular protein transmembrane transport (GO:0065002)2.43805391
157oxidative phosphorylation (GO:0006119)2.43732621
158dopamine biosynthetic process (GO:0042416)2.43726877
159response to pheromone (GO:0019236)2.43481452
160glycolipid biosynthetic process (GO:0009247)2.43305749
161xenobiotic catabolic process (GO:0042178)2.43129474
162protein targeting to ER (GO:0045047)2.43016706
163tissue regeneration (GO:0042246)2.42813763
164ribosomal small subunit assembly (GO:0000028)2.41762396
165adhesion of symbiont to host cell (GO:0044650)2.40876143
166virion attachment to host cell (GO:0019062)2.40876143
167dopamine transport (GO:0015872)2.40530008
168negative regulation of chemokine production (GO:0032682)2.39427260
169protein deneddylation (GO:0000338)2.39347219
170piRNA metabolic process (GO:0034587)2.39089467
171protein localization to endoplasmic reticulum (GO:0070972)2.37657172
172auditory receptor cell stereocilium organization (GO:0060088)2.37596142
173negative regulation of reactive oxygen species metabolic process (GO:2000378)2.37215974
174nonmotile primary cilium assembly (GO:0035058)2.36055801
175rRNA modification (GO:0000154)2.35868986
176C-terminal protein lipidation (GO:0006501)2.32823917

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.97467889
2ZNF274_21170338_ChIP-Seq_K562_Hela3.59522852
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.50935798
4GBX2_23144817_ChIP-Seq_PC3_Human3.31144923
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.95551753
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.95331380
7EZH2_22144423_ChIP-Seq_EOC_Human2.88892612
8TAF15_26573619_Chip-Seq_HEK293_Human2.72411771
9SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.41061506
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.31844930
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.24568377
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.19104567
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.18747676
14SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.15223294
15TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.14120995
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08473615
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.07001294
18JARID2_20064375_ChIP-Seq_MESCs_Mouse2.05443131
19VDR_22108803_ChIP-Seq_LS180_Human2.04692308
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.03076532
21SRF_21415370_ChIP-Seq_HL-1_Mouse2.01818797
22ER_23166858_ChIP-Seq_MCF-7_Human1.98354736
23EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.93600188
24ELK1_19687146_ChIP-ChIP_HELA_Human1.91431397
25EZH2_27304074_Chip-Seq_ESCs_Mouse1.90010643
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.85174071
27OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.83917736
28CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.81580529
29MYC_18940864_ChIP-ChIP_HL60_Human1.81384658
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.80393780
31CDX2_19796622_ChIP-Seq_MESCs_Mouse1.77863800
32MTF2_20144788_ChIP-Seq_MESCs_Mouse1.75673969
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74198571
34VDR_23849224_ChIP-Seq_CD4+_Human1.73920378
35POU3F2_20337985_ChIP-ChIP_501MEL_Human1.73148724
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.72970043
37SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.71296301
38RNF2_18974828_ChIP-Seq_MESCs_Mouse1.70011890
39EZH2_18974828_ChIP-Seq_MESCs_Mouse1.70011890
40SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.69283086
41FUS_26573619_Chip-Seq_HEK293_Human1.66539840
42JARID2_20075857_ChIP-Seq_MESCs_Mouse1.61033699
43SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.60472813
44TP53_22573176_ChIP-Seq_HFKS_Human1.58918638
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.57736600
46MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.57328253
47EZH2_27294783_Chip-Seq_ESCs_Mouse1.53913235
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.53858617
49SUZ12_27294783_Chip-Seq_ESCs_Mouse1.52586524
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52519700
51P300_19829295_ChIP-Seq_ESCs_Human1.46338390
52CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.44538514
53RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41092977
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.39387076
55HTT_18923047_ChIP-ChIP_STHdh_Human1.38428149
56CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.38273680
57AR_20517297_ChIP-Seq_VCAP_Human1.38145439
58CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33913780
59FOXA1_27270436_Chip-Seq_PROSTATE_Human1.33414484
60FOXA1_25329375_ChIP-Seq_VCAP_Human1.33414484
61CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.31455846
62CREB1_15753290_ChIP-ChIP_HEK293T_Human1.30424783
63PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.30231138
64PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.27788180
65GATA3_21878914_ChIP-Seq_MCF-7_Human1.27367348
66RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26750710
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26046551
68PIAS1_25552417_ChIP-Seq_VCAP_Human1.25433156
69RNF2_27304074_Chip-Seq_ESCs_Mouse1.24263064
70AR_21572438_ChIP-Seq_LNCaP_Human1.23157118
71NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.22651829
72NRF2_20460467_ChIP-Seq_MEFs_Mouse1.22651829
73CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.22477710
74NCOR_22424771_ChIP-Seq_293T_Human1.22249358
75FOXP3_21729870_ChIP-Seq_TREG_Human1.19990410
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.19839318
77TAL1_26923725_Chip-Seq_HPCs_Mouse1.19277643
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.18700398
79ETV2_25802403_ChIP-Seq_MESCs_Mouse1.17748507
80IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17592063
81CBP_20019798_ChIP-Seq_JUKART_Human1.17592063
82PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16968073
83EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.15760941
84CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.15408354
85CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.15124112
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.14364816
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13761489
88EP300_21415370_ChIP-Seq_HL-1_Mouse1.13491229
89PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13363069
90NANOG_20526341_ChIP-Seq_ESCs_Human1.13248323
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13231007
92TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12799304
93NANOG_19829295_ChIP-Seq_ESCs_Human1.11739313
94SOX2_19829295_ChIP-Seq_ESCs_Human1.11739313
95NANOG_18555785_Chip-Seq_ESCs_Mouse1.10373648
96EGR1_23403033_ChIP-Seq_LIVER_Mouse1.10053443
97AR_25329375_ChIP-Seq_VCAP_Human1.09557581
98SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08495856
99RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.08198910
100HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.07198504
101HOXB7_26014856_ChIP-Seq_BT474_Human1.06263364
102BCAT_22108803_ChIP-Seq_LS180_Human1.04648865
103CMYC_18555785_Chip-Seq_ESCs_Mouse1.04046066
104P300_18555785_Chip-Seq_ESCs_Mouse1.04006353
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.03985793
106MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03695009
107MYC_19829295_ChIP-Seq_ESCs_Human1.03367568
108AUTS2_25519132_ChIP-Seq_293T-REX_Human1.02855105
109FOXH1_21741376_ChIP-Seq_EPCs_Human1.02563004
110FLI1_27457419_Chip-Seq_LIVER_Mouse1.02551339
111NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02506841
112ERA_21632823_ChIP-Seq_H3396_Human1.02340505
113ERG_20517297_ChIP-Seq_VCAP_Human1.00676925
114EWS_26573619_Chip-Seq_HEK293_Human1.00611732
115FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99985360
116LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99529658
117PRDM14_20953172_ChIP-Seq_ESCs_Human0.99465498
118EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.99451360
119EOMES_21245162_ChIP-Seq_HESCs_Human0.98604306
120TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98401028
121NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.98000837
122SMAD4_21799915_ChIP-Seq_A2780_Human0.97964142
123TCF4_22108803_ChIP-Seq_LS180_Human0.97651737
124TAF2_19829295_ChIP-Seq_ESCs_Human0.97031910
125STAT3_18555785_Chip-Seq_ESCs_Mouse0.96601337
126P53_22387025_ChIP-Seq_ESCs_Mouse0.96566336
127DROSHA_22980978_ChIP-Seq_HELA_Human0.96183461
128WT1_19549856_ChIP-ChIP_CCG9911_Human0.96082686
129STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.95765769
130PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.94575121
131KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.94504595
132RUNX1_27457419_Chip-Seq_LIVER_Mouse0.94222672
133ELK1_22589737_ChIP-Seq_MCF10A_Human0.92461269
134VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.92403644
135SUZ12_27294783_Chip-Seq_NPCs_Mouse0.91780431
136RNF2_27304074_Chip-Seq_NSC_Mouse0.91445416
137IRF1_19129219_ChIP-ChIP_H3396_Human0.91166807
138CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.91133204
139SOX2_18555785_Chip-Seq_ESCs_Mouse0.91042144
140AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90951077
141SMAD4_21741376_ChIP-Seq_EPCs_Human0.90918463
142GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.90870019
143IGF1R_20145208_ChIP-Seq_DFB_Human0.90740029
144KDM2B_26808549_Chip-Seq_REH_Human0.90728751
145REST_21632747_ChIP-Seq_MESCs_Mouse0.90600977
146PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.89536896
147EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.88751170
148E2F1_18555785_Chip-Seq_ESCs_Mouse0.88648715
149EZH2_27294783_Chip-Seq_NPCs_Mouse0.88259840
150KLF4_18555785_Chip-Seq_ESCs_Mouse0.87986948
151HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.87915412
152SMAD1_18555785_Chip-Seq_ESCs_Mouse0.87343158
153P53_21459846_ChIP-Seq_SAOS-2_Human0.87263562
154PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.86680811
155NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.85829150
156FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.85597275
157RUNX2_22187159_ChIP-Seq_PCA_Human0.85490469

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination4.14510563
2MP0003880_abnormal_central_pattern4.01453587
3MP0001529_abnormal_vocalization3.56980976
4MP0003950_abnormal_plasma_membrane3.04468775
5MP0001905_abnormal_dopamine_level2.89530105
6MP0004270_analgesia2.68315130
7MP0003690_abnormal_glial_cell2.35358710
8MP0002102_abnormal_ear_morphology2.34613873
9MP0002272_abnormal_nervous_system2.25706219
10MP0001486_abnormal_startle_reflex2.20111014
11MP0004142_abnormal_muscle_tone2.19277768
12MP0003136_yellow_coat_color2.09252850
13MP0003806_abnormal_nucleotide_metabolis2.06991882
14MP0003329_amyloid_beta_deposits2.06682294
15MP0005409_darkened_coat_color2.05126800
16MP0004145_abnormal_muscle_electrophysio2.00168351
17MP0002638_abnormal_pupillary_reflex1.99654173
18MP0004742_abnormal_vestibular_system1.99149632
19MP0002938_white_spotting1.97738688
20MP0005451_abnormal_body_composition1.96619490
21MP0005171_absent_coat_pigmentation1.95968554
22MP0000749_muscle_degeneration1.95816293
23MP0004147_increased_porphyrin_level1.95350955
24MP0006292_abnormal_olfactory_placode1.94711769
25MP0001485_abnormal_pinna_reflex1.90438375
26MP0003011_delayed_dark_adaptation1.86363078
27MP0002064_seizures1.85169797
28MP0002837_dystrophic_cardiac_calcinosis1.83074901
29MP0005084_abnormal_gallbladder_morpholo1.69175232
30MP0004885_abnormal_endolymph1.68849995
31MP0004036_abnormal_muscle_relaxation1.68766441
32MP0003878_abnormal_ear_physiology1.68749101
33MP0005377_hearing/vestibular/ear_phenot1.68749101
34MP0005253_abnormal_eye_physiology1.67924631
35MP0005410_abnormal_fertilization1.65323222
36MP0004043_abnormal_pH_regulation1.64977937
37MP0000751_myopathy1.64853589
38MP0003634_abnormal_glial_cell1.64201033
39MP0002653_abnormal_ependyma_morphology1.64003385
40MP0008875_abnormal_xenobiotic_pharmacok1.63598101
41MP0009745_abnormal_behavioral_response1.62471174
42MP0002734_abnormal_mechanical_nocicepti1.59767036
43MP0000778_abnormal_nervous_system1.56693247
44MP0002229_neurodegeneration1.56124420
45MP0001440_abnormal_grooming_behavior1.56057854
46MP0009046_muscle_twitch1.50408972
47MP0000747_muscle_weakness1.48721392
48MP0000462_abnormal_digestive_system1.44472490
49MP0004134_abnormal_chest_morphology1.41226993
50MP0004133_heterotaxia1.41214812
51MP0003635_abnormal_synaptic_transmissio1.40782733
52MP0002160_abnormal_reproductive_system1.38121346
53MP0005551_abnormal_eye_electrophysiolog1.35000042
54MP0008872_abnormal_physiological_respon1.34019319
55MP0002736_abnormal_nociception_after1.31582205
56MP0005174_abnormal_tail_pigmentation1.30174238
57MP0002277_abnormal_respiratory_mucosa1.29227897
58MP0004924_abnormal_behavior1.26924013
59MP0005386_behavior/neurological_phenoty1.26924013
60MP0002572_abnormal_emotion/affect_behav1.26895039
61MP0001963_abnormal_hearing_physiology1.26870013
62MP0006036_abnormal_mitochondrial_physio1.26735802
63MP0005670_abnormal_white_adipose1.26491004
64MP0005645_abnormal_hypothalamus_physiol1.22919975
65MP0002067_abnormal_sensory_capabilities1.22820693
66MP0000631_abnormal_neuroendocrine_gland1.22431264
67MP0001970_abnormal_pain_threshold1.22378256
68MP0001968_abnormal_touch/_nociception1.22149095
69MP0006276_abnormal_autonomic_nervous1.21823086
70MP0004381_abnormal_hair_follicle1.21662479
71MP0003137_abnormal_impulse_conducting1.20885109
72MP0008775_abnormal_heart_ventricle1.20456773
73MP0008877_abnormal_DNA_methylation1.16671241
74MP0009379_abnormal_foot_pigmentation1.15743969
75MP0008789_abnormal_olfactory_epithelium1.15164687
76MP0002095_abnormal_skin_pigmentation1.14837690
77MP0004859_abnormal_synaptic_plasticity1.14544554
78MP0003632_abnormal_nervous_system1.13471729
79MP0005075_abnormal_melanosome_morpholog1.12734629
80MP0002735_abnormal_chemical_nociception1.12456608
81MP0008569_lethality_at_weaning1.11006082
82MP0000569_abnormal_digit_pigmentation1.10206264
83MP0002063_abnormal_learning/memory/cond1.09323608
84MP0002066_abnormal_motor_capabilities/c1.09262278
85MP0004084_abnormal_cardiac_muscle1.07043908
86MP0001764_abnormal_homeostasis1.06601567
87MP0001661_extended_life_span1.06590221
88MP0003631_nervous_system_phenotype1.05720623
89MP0005389_reproductive_system_phenotype1.05286545
90MP0008260_abnormal_autophagy1.05189574
91MP0008995_early_reproductive_senescence1.04417799
92MP0002752_abnormal_somatic_nervous1.03011420
93MP0004215_abnormal_myocardial_fiber1.02655350
94MP0000372_irregular_coat_pigmentation1.02118391
95MP0002882_abnormal_neuron_morphology1.01953499
96MP0005330_cardiomyopathy1.00757253
97MP0010678_abnormal_skin_adnexa1.00707224
98MP0005423_abnormal_somatic_nervous1.00657291
99MP0002733_abnormal_thermal_nociception1.00558189
100MP0005620_abnormal_muscle_contractility0.99843056
101MP0001984_abnormal_olfaction0.98795527
102MP0003633_abnormal_nervous_system0.97635468
103MP0002822_catalepsy0.97534187
104MP0004130_abnormal_muscle_cell0.96634672
105MP0003938_abnormal_ear_development0.96524979
106MP0000383_abnormal_hair_follicle0.96092297
107MP0002234_abnormal_pharynx_morphology0.95463203
108MP0005266_abnormal_metabolism0.95298640
109MP0005332_abnormal_amino_acid0.95280461
110MP0000230_abnormal_systemic_arterial0.94941347
111MP0002295_abnormal_pulmonary_circulatio0.94424058
112MP0010386_abnormal_urinary_bladder0.93978613
113MP0004484_altered_response_of0.93835665
114MP0000955_abnormal_spinal_cord0.93775303
115MP0000604_amyloidosis0.93652691
116MP0001324_abnormal_eye_pigmentation0.93644069
117MP0000026_abnormal_inner_ear0.93587752
118MP0003718_maternal_effect0.92706162
119MP0002106_abnormal_muscle_physiology0.90566238
120MP0005167_abnormal_blood-brain_barrier0.89823037
121MP0000762_abnormal_tongue_morphology0.89037742
122MP0009250_abnormal_appendicular_skeleto0.88813632
123MP0001501_abnormal_sleep_pattern0.88722725
124MP0003195_calcinosis0.87533365
125MP0010030_abnormal_orbit_morphology0.86572851
126MP0005369_muscle_phenotype0.86050457
127MP0002332_abnormal_exercise_endurance0.85953773
128MP0004085_abnormal_heartbeat0.85504854
129MP0000750_abnormal_muscle_regeneration0.85499879
130MP0003186_abnormal_redox_activity0.84832291
131MP0002876_abnormal_thyroid_physiology0.84654056
132MP0003646_muscle_fatigue0.83484319
133MP0000566_synostosis0.81579904
134MP0005195_abnormal_posterior_eye0.81163539
135MP0001293_anophthalmia0.80462161
136MP0009697_abnormal_copulation0.79528577
137MP0008058_abnormal_DNA_repair0.79267595
138MP0002282_abnormal_trachea_morphology0.78644745
139MP0005646_abnormal_pituitary_gland0.78300537
140MP0005408_hypopigmentation0.77657675
141MP0001188_hyperpigmentation0.75434318
142MP0006072_abnormal_retinal_apoptosis0.74940345
143MP0002972_abnormal_cardiac_muscle0.74340135
144MP0001664_abnormal_digestion0.74340105
145MP0001346_abnormal_lacrimal_gland0.74289095
146MP0000049_abnormal_middle_ear0.73803198
147MP0001986_abnormal_taste_sensitivity0.72904714
148MP0005391_vision/eye_phenotype0.71201364
149MP0002557_abnormal_social/conspecific_i0.70632035
150MP0006035_abnormal_mitochondrial_morpho0.70559360

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.12170887
2Degeneration of the lateral corticospinal tracts (HP:0002314)4.93216079
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.93216079
4Abnormal mitochondria in muscle tissue (HP:0008316)4.50440467
5Increased serum pyruvate (HP:0003542)4.41805542
6Abnormality of glycolysis (HP:0004366)4.41805542
7Acute encephalopathy (HP:0006846)4.40326684
8Mitochondrial inheritance (HP:0001427)4.38872016
9Parakeratosis (HP:0001036)4.34169062
10Neurofibrillary tangles (HP:0002185)4.32740096
11Progressive macrocephaly (HP:0004481)4.26808274
12Hepatocellular necrosis (HP:0001404)4.02009097
13Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.75583677
14Leukodystrophy (HP:0002415)3.72307718
15Pancreatic cysts (HP:0001737)3.71608666
16Increased CSF lactate (HP:0002490)3.62248884
17Pancreatic fibrosis (HP:0100732)3.61950497
18True hermaphroditism (HP:0010459)3.59959583
19Abnormality of midbrain morphology (HP:0002418)3.56159031
20Molar tooth sign on MRI (HP:0002419)3.56159031
21Hepatic necrosis (HP:0002605)3.45329965
22Renal Fanconi syndrome (HP:0001994)3.38470452
23Abnormality of the corticospinal tract (HP:0002492)3.37694037
24Congenital stationary night blindness (HP:0007642)3.22025678
25Increased hepatocellular lipid droplets (HP:0006565)3.19722136
26Muscle hypertrophy of the lower extremities (HP:0008968)3.07784052
27Cerebral inclusion bodies (HP:0100314)3.05151661
28Nephronophthisis (HP:0000090)3.04974384
29Cerebral edema (HP:0002181)2.99715654
30Abnormality of alanine metabolism (HP:0010916)2.99038902
31Hyperalaninemia (HP:0003348)2.99038902
32Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.99038902
33Lipid accumulation in hepatocytes (HP:0006561)2.96282962
34Sensory axonal neuropathy (HP:0003390)2.95628428
35Respiratory failure (HP:0002878)2.92449232
36Muscle fiber splitting (HP:0003555)2.90310969
37Congenital, generalized hypertrichosis (HP:0004540)2.89543752
383-Methylglutaconic aciduria (HP:0003535)2.86948011
39Pheochromocytoma (HP:0002666)2.85738706
40Peripheral hypomyelination (HP:0007182)2.84935565
41Optic disc pallor (HP:0000543)2.82769913
42Methylmalonic acidemia (HP:0002912)2.79991513
43Medial flaring of the eyebrow (HP:0010747)2.79736911
44Congenital ichthyosiform erythroderma (HP:0007431)2.70573013
45Neuroendocrine neoplasm (HP:0100634)2.70468020
46Type II lissencephaly (HP:0007260)2.67439485
47Retinal dysplasia (HP:0007973)2.66276093
48Cerebral hypomyelination (HP:0006808)2.62014785
49Abnormality of the renal cortex (HP:0011035)2.61461233
50Cerebral hemorrhage (HP:0001342)2.58680357
51Nemaline bodies (HP:0003798)2.57978549
52Large for gestational age (HP:0001520)2.57717800
53Abnormality of the renal medulla (HP:0100957)2.54793284
54Stridor (HP:0010307)2.54154498
55Calf muscle hypertrophy (HP:0008981)2.53191045
56Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.51528577
57Abnormal number of erythroid precursors (HP:0012131)2.47669776
58Lactic acidosis (HP:0003128)2.44916668
59Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.40212974
60Muscle fiber inclusion bodies (HP:0100299)2.39439633
61Exercise-induced muscle cramps (HP:0003710)2.38713047
62Increased intramyocellular lipid droplets (HP:0012240)2.37783272
63Myokymia (HP:0002411)2.35634240
64Onion bulb formation (HP:0003383)2.35323044
65Exercise intolerance (HP:0003546)2.35261516
66Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.33278443
67Sclerocornea (HP:0000647)2.32284573
68Renal cortical cysts (HP:0000803)2.29183079
69Gowers sign (HP:0003391)2.24795572
70Spastic gait (HP:0002064)2.21091559
71Termporal pattern (HP:0011008)2.20900929
72Insidious onset (HP:0003587)2.20900929
73Cystic liver disease (HP:0006706)2.20874741
74Exercise-induced myalgia (HP:0003738)2.20840325
75Abnormality of renal resorption (HP:0011038)2.19154500
76Supranuclear gaze palsy (HP:0000605)2.18618474
77Methylmalonic aciduria (HP:0012120)2.18156709
78Abnormal respiratory motile cilium morphology (HP:0005938)2.17828115
79Abnormal respiratory epithelium morphology (HP:0012253)2.17828115
80Abnormality of cells of the erythroid lineage (HP:0012130)2.17507823
81Increased serum lactate (HP:0002151)2.16488389
82X-linked dominant inheritance (HP:0001423)2.14430052
83Increased muscle lipid content (HP:0009058)2.13251407
84Congenital primary aphakia (HP:0007707)2.12707890
85Hyperglycinemia (HP:0002154)2.10425381
86Hypoplastic pelvis (HP:0008839)2.10276954
87Gait imbalance (HP:0002141)2.09582713
88Focal motor seizures (HP:0011153)2.07213261
89Aplasia/Hypoplasia of the tongue (HP:0010295)2.06606141
90Glycosuria (HP:0003076)2.06374861
91Abnormality of urine glucose concentration (HP:0011016)2.06374861
92Spastic paraparesis (HP:0002313)2.06201501
93Polydipsia (HP:0001959)2.05903270
94Abnormal drinking behavior (HP:0030082)2.05903270
95Hyperventilation (HP:0002883)2.05729618
96Type I transferrin isoform profile (HP:0003642)2.03068082
97Decreased electroretinogram (ERG) amplitude (HP:0000654)2.02737936
98Congenital hepatic fibrosis (HP:0002612)2.02610766
99Dysmetria (HP:0001310)2.02492315
100Nephrogenic diabetes insipidus (HP:0009806)2.01802729
101Abnormal auditory evoked potentials (HP:0006958)1.98948046
102Tubular atrophy (HP:0000092)1.97047533
103Anencephaly (HP:0002323)1.96513096
104Autoamputation (HP:0001218)1.96427396
105Bile duct proliferation (HP:0001408)1.95723212
106Abnormal biliary tract physiology (HP:0012439)1.95723212
107Male pseudohermaphroditism (HP:0000037)1.95722582
108Severe muscular hypotonia (HP:0006829)1.95712130
109CNS demyelination (HP:0007305)1.95686592
110Abolished electroretinogram (ERG) (HP:0000550)1.93786937
111Concave nail (HP:0001598)1.93465139
112Attenuation of retinal blood vessels (HP:0007843)1.93451933
113Absent septum pellucidum (HP:0001331)1.91866280
114Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.91243210
115Decreased activity of mitochondrial respiratory chain (HP:0008972)1.91243210
116Abnormal ciliary motility (HP:0012262)1.90927846
117Abnormality of placental membranes (HP:0011409)1.90107196
118Amniotic constriction ring (HP:0009775)1.90107196
119Hypoplastic left heart (HP:0004383)1.88975230
120Abnormal rod and cone electroretinograms (HP:0008323)1.88668904
121Chronic hepatic failure (HP:0100626)1.87784914
122Hyperglycinuria (HP:0003108)1.86610507
123Inability to walk (HP:0002540)1.85558483
124Abnormal protein glycosylation (HP:0012346)1.85490359
125Abnormal glycosylation (HP:0012345)1.85490359
126Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.85490359
127Abnormal protein N-linked glycosylation (HP:0012347)1.85490359
128Dynein arm defect of respiratory motile cilia (HP:0012255)1.85032225
129Absent/shortened dynein arms (HP:0200106)1.85032225
130Akinesia (HP:0002304)1.84701849
131Pendular nystagmus (HP:0012043)1.84167062
132Hyporeflexia of lower limbs (HP:0002600)1.83233010
133Metabolic alkalosis (HP:0200114)1.83012490
134Ketosis (HP:0001946)1.82761769
135Birth length less than 3rd percentile (HP:0003561)1.82150942
136Aplasia/Hypoplasia of the tibia (HP:0005772)1.81572404
137Furrowed tongue (HP:0000221)1.80439247
138Rimmed vacuoles (HP:0003805)1.79807604
139Scanning speech (HP:0002168)1.79278065
140CNS hypomyelination (HP:0003429)1.79230347
141Generalized aminoaciduria (HP:0002909)1.77399999
142Optic nerve hypoplasia (HP:0000609)1.76801933
143Patchy hypopigmentation of hair (HP:0011365)1.76120309
144Slow saccadic eye movements (HP:0000514)1.75203228
145Hypoplastic heart (HP:0001961)1.72851868
146Poor speech (HP:0002465)1.72802285
147Exertional dyspnea (HP:0002875)1.72341039
148Nonprogressive disorder (HP:0003680)1.71539347
149Split foot (HP:0001839)1.70989197
150Prolonged neonatal jaundice (HP:0006579)1.70700685
151Hypomagnesemia (HP:0002917)1.69800016
152Hepatosplenomegaly (HP:0001433)1.67998355
153Lethargy (HP:0001254)1.67010535
154Abnormality of the septum pellucidum (HP:0007375)1.66697439
155EMG: myopathic abnormalities (HP:0003458)1.66511637
156Alacrima (HP:0000522)1.66247534
157Foot dorsiflexor weakness (HP:0009027)1.65816497
158Synostosis involving the elbow (HP:0003938)1.65784905
159Humeroradial synostosis (HP:0003041)1.65784905
160Abnormality of the calf musculature (HP:0001430)1.64212881
161Abnormality of the vitamin B12 metabolism (HP:0004341)1.64034802
162Vaginal atresia (HP:0000148)1.62312826
163Abnormality of the phalanges of the 2nd finger (HP:0009541)1.61579109
164White forelock (HP:0002211)1.60899445

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.76913344
2OXSR14.16674982
3FRK3.30156244
4VRK22.77045643
5MAPKAPK52.71007253
6PBK2.59533296
7MAP4K22.58875950
8BCR2.58869990
9WNK42.45021310
10CASK2.40532156
11CDK192.32035463
12TNIK2.28049655
13ZAK2.25638137
14EPHB12.21826693
15PKN12.20364929
16MUSK2.17151796
17MST42.11854550
18LIMK12.01479974
19STK162.00174312
20NUAK11.91031980
21NME11.88283966
22WNK31.85117610
23INSRR1.81161291
24ACVR1B1.72093775
25CSNK1G31.69814070
26CAMK2B1.62311043
27EPHA41.59253158
28OBSCN1.57530935
29PNCK1.55149306
30CAMK2D1.52330464
31TIE11.47648036
32PHKG21.45944468
33PHKG11.45944468
34MET1.45395526
35TGFBR11.42750714
36MAPKAPK31.37995764
37CSNK1A1L1.35412019
38WNK11.33297867
39ROCK21.28529499
40CSNK1G11.25897777
41BMPR1B1.24344273
42WEE11.23902749
43CSNK1G21.21175734
44SGK4941.20420439
45SGK2231.20420439
46FGFR21.19745002
47FGR1.19537528
48ARAF1.16048282
49CAMK2G1.15622012
50UHMK11.14206784
51TESK21.10459070
52GRK71.09658341
53CAMK2A1.06367360
54BUB11.02927952
55CLK11.01617958
56PIK3CA1.01454333
57NEK61.00314181
58MARK30.98315021
59DAPK20.96181682
60PRPF4B0.94048290
61MYLK0.93161608
62TAOK30.88226366
63DYRK20.86582544
64NTRK10.85570793
65ADRBK20.85355427
66PRKCQ0.83109360
67EPHB20.81021650
68GRK50.78751990
69CCNB10.76734197
70MARK10.76527583
71PRKCE0.76457479
72CDK80.74301892
73STK38L0.74068084
74BRSK20.73691642
75PLK40.72660146
76IRAK20.71953736
77ERBB30.70805865
78PLK30.70528723
79MAP3K40.70405504
80MAPK150.69338816
81BMPR20.68133446
82PAK30.67771032
83MAPK130.67470427
84TRIM280.66976837
85PRKCG0.66871187
86CDK140.65975029
87EIF2AK30.65935422
88PINK10.64372485
89MAP2K70.63047770
90MAP2K20.63016591
91TXK0.59773589
92CDK50.58329138
93PIK3CG0.57937837
94PRKD10.55660699
95CAMKK20.54525192
96PRKG10.54296627
97MKNK20.54128554
98DYRK30.53669728
99PRKACA0.51523760
100IKBKB0.51102732
101NEK20.51072279
102CDK150.50284394
103CDK180.48209716
104PLK10.47760699
105PRKACB0.47476012
106NEK10.47346843
107CDK11A0.46333433
108RPS6KA50.45416689
109ERBB40.44786731
110CAMK10.44007294
111PLK20.43508903
112MAP3K120.43116422
113ADRBK10.42874939
114MARK20.42657308
115PDPK10.41975353
116CDK30.41794205
117PAK60.41556411
118MAP2K60.41480368
119GRK10.41114314
120PTK2B0.40745163
121VRK10.40649581
122DAPK30.40580912
123IRAK10.40385512
124MAPK120.39984286
125PIM20.39781067
126LMTK20.38448313
127KIT0.38086775
128MKNK10.37932562
129NME20.37745712
130CSNK1A10.37673300
131ABL20.37567629
132TAF10.36969499
133PRKCI0.36430673
134CSNK2A10.36302892
135FYN0.34218063
136TRPM70.33086336
137FES0.32995322
138ILK0.32714933
139BCKDK0.31941952
140TLK10.30081077
141PDK20.29987781
142CSNK1D0.28610405
143TYRO30.26999512
144PRKCA0.26787914
145PRKAA20.26764317

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.68207756
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.40692265
3Fatty acid elongation_Homo sapiens_hsa000624.02245211
4Parkinsons disease_Homo sapiens_hsa050123.80546291
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.57948680
6Steroid biosynthesis_Homo sapiens_hsa001003.35488519
7Alzheimers disease_Homo sapiens_hsa050103.11909334
8Huntingtons disease_Homo sapiens_hsa050162.46082727
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.37439322
10Ether lipid metabolism_Homo sapiens_hsa005652.33032296
11Protein export_Homo sapiens_hsa030602.32850916
12Sulfur metabolism_Homo sapiens_hsa009202.30493315
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.22549210
14Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.20174509
15Nitrogen metabolism_Homo sapiens_hsa009102.14181079
16Cardiac muscle contraction_Homo sapiens_hsa042602.07139609
17Homologous recombination_Homo sapiens_hsa034401.76618197
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.76125573
19Butanoate metabolism_Homo sapiens_hsa006501.70814347
20Histidine metabolism_Homo sapiens_hsa003401.65990500
21Propanoate metabolism_Homo sapiens_hsa006401.62760157
22Vitamin B6 metabolism_Homo sapiens_hsa007501.60390498
23Linoleic acid metabolism_Homo sapiens_hsa005911.57159708
24Tryptophan metabolism_Homo sapiens_hsa003801.52625959
25Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.46153874
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36342562
27alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.36212879
28Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.31955692
29Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.29695976
30Maturity onset diabetes of the young_Homo sapiens_hsa049501.29149805
31Collecting duct acid secretion_Homo sapiens_hsa049661.25384450
32Sphingolipid metabolism_Homo sapiens_hsa006001.23055466
33Selenocompound metabolism_Homo sapiens_hsa004501.20279592
34Primary bile acid biosynthesis_Homo sapiens_hsa001201.19915163
35Arginine and proline metabolism_Homo sapiens_hsa003301.17329233
36Fanconi anemia pathway_Homo sapiens_hsa034601.17105715
37Pyruvate metabolism_Homo sapiens_hsa006201.12240437
38Peroxisome_Homo sapiens_hsa041461.10071188
39RNA degradation_Homo sapiens_hsa030181.07772246
40Glutathione metabolism_Homo sapiens_hsa004801.04794461
41One carbon pool by folate_Homo sapiens_hsa006701.00874812
42Purine metabolism_Homo sapiens_hsa002300.98795214
43Proteasome_Homo sapiens_hsa030500.97935508
44Arachidonic acid metabolism_Homo sapiens_hsa005900.96056637
45Fatty acid metabolism_Homo sapiens_hsa012120.95433547
46Pyrimidine metabolism_Homo sapiens_hsa002400.95311297
47Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.94234349
48Serotonergic synapse_Homo sapiens_hsa047260.94025269
49Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.91145801
50Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.90726270
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89303112
52Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.88702060
53Metabolic pathways_Homo sapiens_hsa011000.86874203
54Vibrio cholerae infection_Homo sapiens_hsa051100.86618638
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85951628
56Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83756222
57Caffeine metabolism_Homo sapiens_hsa002320.81899187
58Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81777279
59Axon guidance_Homo sapiens_hsa043600.81416715
60GABAergic synapse_Homo sapiens_hsa047270.81379772
61Chemical carcinogenesis_Homo sapiens_hsa052040.80557783
62SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79467169
63Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.79202071
64Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.79031504
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.77331249
66Nucleotide excision repair_Homo sapiens_hsa034200.76761792
67Olfactory transduction_Homo sapiens_hsa047400.76418029
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.76202116
69RNA polymerase_Homo sapiens_hsa030200.75285302
70Ribosome_Homo sapiens_hsa030100.74910498
71Steroid hormone biosynthesis_Homo sapiens_hsa001400.74480042
72Glutamatergic synapse_Homo sapiens_hsa047240.71676207
73Nicotine addiction_Homo sapiens_hsa050330.69477166
74Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.67463706
75Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.65001571
76Mismatch repair_Homo sapiens_hsa034300.64014740
77Phototransduction_Homo sapiens_hsa047440.63669220
78Pentose and glucuronate interconversions_Homo sapiens_hsa000400.63313694
79Rheumatoid arthritis_Homo sapiens_hsa053230.62212024
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.59700186
81Morphine addiction_Homo sapiens_hsa050320.55753402
82Circadian rhythm_Homo sapiens_hsa047100.54824813
83Long-term depression_Homo sapiens_hsa047300.54151999
84Glycerophospholipid metabolism_Homo sapiens_hsa005640.53544101
85Mineral absorption_Homo sapiens_hsa049780.52324670
86Folate biosynthesis_Homo sapiens_hsa007900.52130110
87Tyrosine metabolism_Homo sapiens_hsa003500.50007750
88Tight junction_Homo sapiens_hsa045300.49307741
89Retinol metabolism_Homo sapiens_hsa008300.49205029
90beta-Alanine metabolism_Homo sapiens_hsa004100.46355684
91Regulation of autophagy_Homo sapiens_hsa041400.45805416
92Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.43315126
93Circadian entrainment_Homo sapiens_hsa047130.42855927
94Sulfur relay system_Homo sapiens_hsa041220.42572860
95Vitamin digestion and absorption_Homo sapiens_hsa049770.42362457
96Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41986152
97Base excision repair_Homo sapiens_hsa034100.41941722
98Salivary secretion_Homo sapiens_hsa049700.40751426
99Fatty acid degradation_Homo sapiens_hsa000710.40676639
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.40568576
101Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.40311329
102Autoimmune thyroid disease_Homo sapiens_hsa053200.39459713
103Cocaine addiction_Homo sapiens_hsa050300.39173638
104ABC transporters_Homo sapiens_hsa020100.37382005
105Intestinal immune network for IgA production_Homo sapiens_hsa046720.35628677
106Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.34116999
107Calcium signaling pathway_Homo sapiens_hsa040200.34030043
108Pancreatic secretion_Homo sapiens_hsa049720.33377196
109Insulin secretion_Homo sapiens_hsa049110.32089833
110Taste transduction_Homo sapiens_hsa047420.32018634
111Fatty acid biosynthesis_Homo sapiens_hsa000610.31727217
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31218644
113Carbon metabolism_Homo sapiens_hsa012000.30394777
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.30331040
115PPAR signaling pathway_Homo sapiens_hsa033200.30316666
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.30242754
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30224992
118Dopaminergic synapse_Homo sapiens_hsa047280.30175529
119Gastric acid secretion_Homo sapiens_hsa049710.29439694
120Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28898933
121Phenylalanine metabolism_Homo sapiens_hsa003600.27830063
122Cholinergic synapse_Homo sapiens_hsa047250.26014285
123Glycerolipid metabolism_Homo sapiens_hsa005610.25617407
124Basal transcription factors_Homo sapiens_hsa030220.25291861
125Fat digestion and absorption_Homo sapiens_hsa049750.25027117
126Ras signaling pathway_Homo sapiens_hsa040140.24899573
127Renin secretion_Homo sapiens_hsa049240.23069798
128Amphetamine addiction_Homo sapiens_hsa050310.22994995
129Dilated cardiomyopathy_Homo sapiens_hsa054140.22964801
130Synaptic vesicle cycle_Homo sapiens_hsa047210.22294669
131Phagosome_Homo sapiens_hsa041450.21059587
132Ovarian steroidogenesis_Homo sapiens_hsa049130.20729140
133Renal cell carcinoma_Homo sapiens_hsa052110.20576978
134Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.20309692

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