Name

MRE11B Gene

MRE11 meiotic recombination 11 homolog B (pseudogene)

MRE11A Gene

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

mre11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11 complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mre11 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

mre11 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mre11 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

MRN complex (MRE11-RAD50-NBS1 complex) Gene Set

From CORUM Protein Complexes

proteins in the MRN complex (MRE11-RAD50-NBS1 complex) protein complex from the CORUM Protein Complexes dataset.

MDC1-MRE11-RAD50-NBS1 complex Gene Set

From CORUM Protein Complexes

proteins in the MDC1-MRE11-RAD50-NBS1 complex protein complex from the CORUM Protein Complexes dataset.

BRCA1-RAD50-MRE11-NBS1 complex Gene Set

From CORUM Protein Complexes

proteins in the BRCA1-RAD50-MRE11-NBS1 complex protein complex from the CORUM Protein Complexes dataset.

R/M complex (RAD50-MRE11 complex) Gene Set

From CORUM Protein Complexes

proteins in the R/M complex (RAD50-MRE11 complex) protein complex from the CORUM Protein Complexes dataset.

MRN complex (MRE11-RAD50-NBN complex) Gene Set

From CORUM Protein Complexes

proteins in the MRN complex (MRE11-RAD50-NBN complex) protein complex from the CORUM Protein Complexes dataset.

MRE11A-RAD50-NBN-TRF2 complex Gene Set

From CORUM Protein Complexes

proteins in the MRE11A-RAD50-NBN-TRF2 complex protein complex from the CORUM Protein Complexes dataset.

MRN-TRRAP complex (MRE11A-RAD50-NBN-TRRAP complex) Gene Set

From CORUM Protein Complexes

proteins in the MRN-TRRAP complex (MRE11A-RAD50-NBN-TRRAP complex) protein complex from the CORUM Protein Complexes dataset.

RAD50-MRE11-NBN-p200-p350 complex Gene Set

From CORUM Protein Complexes

proteins in the RAD50-MRE11-NBN-p200-p350 complex protein complex from the CORUM Protein Complexes dataset.

mre11nbs1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11nbs1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11nbs1rad50regulated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11nbs1rad50regulated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11rad50nbs1dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11rad50nbs1dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11rad50nbs1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11rad50nbs1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11atmrnf168 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11atmrnf168 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11human Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11human in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11rad50nbs1containing Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11rad50nbs1containing in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11rad50nbs1complex Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11rad50nbs1complex in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11rad50 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11rad50 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mre11a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mre11 complex Gene Set

From GO Cellular Component Annotations

proteins localized to the mre11 complex cellular component from the curated GO Cellular Component Annotations dataset.

Mre11, DNA-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mre11, DNA-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein Mre11 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein Mre11 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

MRE11A Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for MRE11A from the NURSA Protein-Protein Interactions dataset.

MRE11A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MRE11A from the Pathway Commons Protein-Protein Interactions dataset.

Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks Gene Set

From Reactome Pathways

proteins participating in the Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks pathway from the Reactome Pathways dataset.