Name

MIR29A Gene

microRNA 29a

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

mir29a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir29a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir29a3p Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir29a3p in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir29ab1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir29ab1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir29abc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir29abc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.