Name

MIR17 Gene

microRNA 17

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

MIR17HG Gene

miR-17-92 cluster host gene

This gene is the host gene for the MIR17-92 cluster, a group of at least six microRNAs (miRNAs) that may be involved in cell survival, proliferation, differentiation, and angiogenesis. Amplification of this gene has been found in several lymphomas and solid tumors. Two non-protein coding transcript variants have been found for this host gene, but only the longest is a polycistronic transcript containing the MIR17-92 cluster. [provided by RefSeq, May 2012]

mir17 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir17 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir1719b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir1719b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir1792 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir1792 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir173p Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir173p in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir175p Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir175p in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir175pmir20a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir175pmir20a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir175pinduced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir175pinduced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir1720 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir1720 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir1720a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir1720a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir17106b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir17106b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir175p20a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir175p20a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mir1792derived Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mir1792derived in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.