Name

LOC100421362 Gene

hydroxysteroid (17-beta) dehydrogenase 12 pseudogene

HSD11B2 Gene

hydroxysteroid (11-beta) dehydrogenase 2

There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010]

HSD11B1 Gene

hydroxysteroid (11-beta) dehydrogenase 1

The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]

HSD17B8 Gene

hydroxysteroid (17-beta) dehydrogenase 8

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

HSD17B1 Gene

hydroxysteroid (17-beta) dehydrogenase 1

HSD17B2 Gene

hydroxysteroid (17-beta) dehydrogenase 2

HSD17B3 Gene

hydroxysteroid (17-beta) dehydrogenase 3

This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]

HSD17B4 Gene

hydroxysteroid (17-beta) dehydrogenase 4

The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

HSD17B6 Gene

hydroxysteroid (17-beta) dehydrogenase 6

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]

HSD17B7 Gene

hydroxysteroid (17-beta) dehydrogenase 7

HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]

HSD17B12 Gene

hydroxysteroid (17-beta) dehydrogenase 12

This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011]

HSD17B13 Gene

hydroxysteroid (17-beta) dehydrogenase 13

HSD17B11 Gene

hydroxysteroid (17-beta) dehydrogenase 11

Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]

HSD17B14 Gene

hydroxysteroid (17-beta) dehydrogenase 14

17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]

HSD17B7P1 Gene

hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 1

HSD17B7P2 Gene

hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2

HSD17B10 Gene

hydroxysteroid (17-beta) dehydrogenase 10

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]

HSDL1 Gene

hydroxysteroid dehydrogenase like 1

HSDL2 Gene

hydroxysteroid dehydrogenase like 2

HSD11B1L Gene

hydroxysteroid (11-beta) dehydrogenase 1-like

This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]

LOC392266 Gene

17beta-hydroxysteroid dehydrogenase pseudogene

HSD17B1P1 Gene

hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1

LOC641708 Gene

hydroxysteroid (17-beta) dehydrogenase 12 pseudogene

H6PD Gene

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells. [provided by RefSeq, Jul 2008]

LOC100421321 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

NDUFA3P3 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 pseudogene 3

LOC440792 Gene

proline dehydrogenase (oxidase) 1 pseudogene

TDH Gene

L-threonine dehydrogenase (pseudogene)

This gene appears to be an evolving pseudogene of L-threonine 3-dehydrogenase (TDH). In both prokaryotes and eukaryotes, TDH catalyzes the first of two steps in one of two L-threonine degradation pathways. However, in human, the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein; the predicted protein lacks most of the C-terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins. This suggests that the human gene is therefore a pseudogene. Transcripts of this gene are found in all tissues and alternatively spliced transcripts have been described. It is not known if these transcripts are translated, or if the possible protein product provides any functional role. [provided by RefSeq, Jul 2008]

NDUFB11P1 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, pseudogene 1

PDK1 Gene

pyruvate dehydrogenase kinase, isozyme 1

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

PDK3 Gene

pyruvate dehydrogenase kinase, isozyme 3

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

PDK2 Gene

pyruvate dehydrogenase kinase, isozyme 2

This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

PDK4 Gene

pyruvate dehydrogenase kinase, isozyme 4

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008]

SRD5A2 Gene

steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]

SRD5A1 Gene

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]

LOC347381 Gene

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit pseudogene

LOC100129843 Gene

pyruvate dehydrogenase kinase, isozyme 1 pseudogene

SDR42E1 Gene

short chain dehydrogenase/reductase family 42E, member 1

LOC100421253 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC100421244 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

GAPDHP39 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 39

GAPDHP38 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 38

GAPDHP31 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 31

GAPDHP30 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 30

GAPDHP33 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 33

GAPDHP32 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 32

GAPDHP35 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 35

GAPDHP34 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 34

GAPDHP37 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 37

GAPDHP36 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 36

LOC100421247 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC100421243 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

MT-ND1 Gene

NADH dehydrogenase, subunit 1 (complex I)

MT-ND3 Gene

NADH dehydrogenase, subunit 3 (complex I)

MT-ND4 Gene

NADH dehydrogenase, subunit 4 (complex I)

MT-ND5 Gene

NADH dehydrogenase, subunit 5 (complex I)

MT-ND6 Gene

NADH dehydrogenase, subunit 6 (complex I)

GLDC Gene

glycine dehydrogenase (decarboxylating)

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010]

DHRS11 Gene

dehydrogenase/reductase (SDR family) member 11

DHRS12 Gene

dehydrogenase/reductase (SDR family) member 12

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

DHRS13 Gene

dehydrogenase/reductase (SDR family) member 13

NDUFA3P1 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 pseudogene 1

ALDH3A2 Gene

aldehyde dehydrogenase 3 family, member A2

Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ALDH3A1 Gene

aldehyde dehydrogenase 3 family, member A1

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

NDUFB1P2 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1 pseudogene 2

PDHA2 Gene

pyruvate dehydrogenase (lipoamide) alpha 2

PDHA1 Gene

pyruvate dehydrogenase (lipoamide) alpha 1

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

NDUFB4P1 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa pseudogene 1

ALDH1B1 Gene

aldehyde dehydrogenase 1 family, member B1

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]

SDR42E2 Gene

short chain dehydrogenase/reductase family 42E, member 2

PDPR Gene

pyruvate dehydrogenase phosphatase regulatory subunit

LDHAL6FP Gene

lactate dehydrogenase A-like 6F, pseudogene

LOC644906 Gene

malate dehydrogenase 1, NAD (soluble) pseudogene

ALDH5A1 Gene

aldehyde dehydrogenase 5 family, member A1

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

PDHX Gene

pyruvate dehydrogenase complex, component X

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

PDHB Gene

pyruvate dehydrogenase (lipoamide) beta

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]

UGDH Gene

UDP-glucose 6-dehydrogenase

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

LOC100884169 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 pseudogene

LOC646709 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 pseudogene

LOC100631258 Gene

isocitrate dehydrogenase 3 (NAD+) gamma pseudogene

LOC100128711 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa pseudogene

GLUD1P4 Gene

glutamate dehydrogenase 1 pseudogene 4

GLUD1P7 Gene

glutamate dehydrogenase 1 pseudogene 7

ALDH3B2 Gene

aldehyde dehydrogenase 3 family, member B2

This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

ALDH3B1 Gene

aldehyde dehydrogenase 3 family, member B1

This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

ACADSB Gene

acyl-CoA dehydrogenase, short/branched chain

Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008]

GAPDHP2 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 2

GAPDHP1 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 1

MTHFD2P6 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 6

LOC2748 Gene

glutamate dehydrogenase 1 pseudogene

LOC100421256 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC100421251 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

MTHFD2P1 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 1

MTHFD2P7 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 7

MTHFD2P5 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 5

MTHFD2P4 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 4

PHGDH Gene

phosphoglycerate dehydrogenase

This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]

LDHAL6EP Gene

lactate dehydrogenase A-like 6E, pseudogene

MTHFD2 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]

HADHAP2 Gene

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 2

LOC100421304 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

DHRS4L1 Gene

dehydrogenase/reductase (SDR family) member 4 like 1

DHRS4L2 Gene

dehydrogenase/reductase (SDR family) member 4 like 2

This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

LOC100128596 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa pseudogene

PGDP2 Gene

phosphogluconate dehydrogenase pseudogene 2

OGDH Gene

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]

AASDH Gene

aminoadipate-semialdehyde dehydrogenase

BDH2 Gene

3-hydroxybutyrate dehydrogenase, type 2

BDH1 Gene

3-hydroxybutyrate dehydrogenase, type 1

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

NDUFV2P1 Gene

NADH dehydrogenase (ubiquinone) flavoprotein 2 pseudogene 1

SRD5A1P1 Gene

steroid-5-alpha-reductase, alpha polypeptide 1 pseudogene 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha pseudogene)

ADH5P2 Gene

alcohol dehydrogenase 5 (class III), chi polypeptide, pseudogene 2

ALDH18A1 Gene

aldehyde dehydrogenase 18 family, member A1

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]

ACADVL Gene

acyl-CoA dehydrogenase, very long chain

The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

GLDCP1 Gene

glycine dehydrogenase (decarboxylase) pseudogene 1

GAPDHP55 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 55

GAPDHP54 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 54

GAPDHP53 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 53

GAPDHP52 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 52

GAPDHP51 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 51

GAPDHP50 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 50

NDUFA11 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa

This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]

NDUFA12 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]

NDUFA13 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13

This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined. [provided by RefSeq, Oct 2009]

ALDH1L2 Gene

aldehyde dehydrogenase 1 family, member L2

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]

ALDH1L1 Gene

aldehyde dehydrogenase 1 family, member L1

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

DHRS7B Gene

dehydrogenase/reductase (SDR family) member 7B

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

DHRS7C Gene

dehydrogenase/reductase (SDR family) member 7C

LOC727919 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 pseudogene

IMPDH1 Gene

IMP (inosine 5'-monophosphate) dehydrogenase 1

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

BCKDK Gene

branched chain ketoacid dehydrogenase kinase

The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

HADHAP1 Gene

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 1

ACAD10 Gene

acyl-CoA dehydrogenase family, member 10

This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008]

ACAD11 Gene

acyl-CoA dehydrogenase family, member 11

ALDH6A1 Gene

aldehyde dehydrogenase 6 family, member A1

This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

LOC100505788 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa pseudogene

GAPDHP76 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 76

LOC728667 Gene

dehydrogenase/reductase (SDR family) member 2 pseudogene

GAPDHP57 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 57

ALDH2 Gene

aldehyde dehydrogenase 2 family (mitochondrial)

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011]

DHODH Gene

dihydroorotate dehydrogenase (quinone)

The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]

NDUFAF5 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 5

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes a mitochondrial protein that is associated with the matrix face of the mitochondrial inner membrane and is required for complex I assembly. A mutation in this gene results in mitochondrial complex I deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

NDUFAF4 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 4

NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency. [provided by RefSeq, Oct 2009]

NDUFAF7 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 7

NDUFAF6 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 6

This gene encodes a protein that localizes to mitochondria and contains a predicted phytoene synthase domain. The encoded protein plays an important role in the assembly of complex I (NADH-ubiquinone oxidoreductase) of the mitochondrial respiratory chain through regulation of subunit ND1 biogenesis. Mutations in this gene are associated with complex I enzymatic deficiency. [provided by RefSeq, Nov 2011]

NDUFAF1 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 1

This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011]

NDUFAF3 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 3

This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2009]

NDUFAF2 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 2

NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency. [provided by RefSeq, Jul 2008]

ADH5P4 Gene

alcohol dehydrogenase 5 (class III), chi polypeptide, pseudogene 4

ADH5P3 Gene

alcohol dehydrogenase 5 (class III), chi polypeptide, pseudogene 3

NDUFB8P1 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, pseudogene 1

NDUFB8P3 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, pseudogene 3

SDHA Gene

succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

SDHC Gene

succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa

This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2013]

SDHB Gene

succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

SDHD Gene

succinate dehydrogenase complex, subunit D, integral membrane protein

This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

LOC100419644 Gene

sorbitol dehydrogenase pseudogene

SDR16C6P Gene

short chain dehydrogenase/reductase family 16C, member 6, pseudogene

GAPDHP26 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 26

GAPDHP25 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 25

GAPDHP22 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 22

GAPDHP23 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 23

GAPDHP20 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 20

GAPDHP21 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 21

GAPDHP29 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 29

LOC100129370 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa pseudogene

GPD1 Gene

glycerol-3-phosphate dehydrogenase 1 (soluble)

This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

GPD2 Gene

glycerol-3-phosphate dehydrogenase 2 (mitochondrial)

The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]

RDH16 Gene

retinol dehydrogenase 16 (all-trans)

RDH10 Gene

retinol dehydrogenase 10 (all-trans)

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]

RDH13 Gene

retinol dehydrogenase 13 (all-trans/9-cis)

This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

ACADS Gene

acyl-CoA dehydrogenase, C-2 to C-3 short chain

This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms. [provided by RefSeq, Oct 2014]

ACADL Gene

acyl-CoA dehydrogenase, long chain

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]

ACADM Gene

acyl-CoA dehydrogenase, C-4 to C-12 straight chain

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ACAD8 Gene

acyl-CoA dehydrogenase family, member 8

This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009]

ACAD9 Gene

acyl-CoA dehydrogenase family, member 9

This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]

SORD Gene

sorbitol dehydrogenase

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]

ALDH1A1 Gene

aldehyde dehydrogenase 1 family, member A1

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]

ALDH1A2 Gene

aldehyde dehydrogenase 1 family, member A2

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]

ALDH1A3 Gene

aldehyde dehydrogenase 1 family, member A3

This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

BDH2P1 Gene

3-hydroxybutyrate dehydrogenase, type 2 pseudogene 1

LOC102724035 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene

DHTKD1 Gene

dehydrogenase E1 and transketolase domain containing 1

This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]

DHRS9 Gene

dehydrogenase/reductase (SDR family) member 9

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

DHRS7 Gene

dehydrogenase/reductase (SDR family) member 7

Short-chain dehydrogenases/reductases (SDRs), such as DHRS7, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]

DHRS4 Gene

dehydrogenase/reductase (SDR family) member 4

DHRS2 Gene

dehydrogenase/reductase (SDR family) member 2

DHRS3 Gene

dehydrogenase/reductase (SDR family) member 3

Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]

DHRS1 Gene

dehydrogenase/reductase (SDR family) member 1

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

DHRSX Gene

dehydrogenase/reductase (SDR family) X-linked

NDUFB4P2 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa pseudogene 2

HSD3BP1 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 1

HSD3BP3 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 3

HSD3BP2 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 2

HSD3BP5 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 5

HSD3BP4 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 4

NDUFB3P5 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa pseudogene 5

GAPDHP24 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 24

GAPDHP28 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 28

IDH3B Gene

isocitrate dehydrogenase 3 (NAD+) beta

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

IDH3G Gene

isocitrate dehydrogenase 3 (NAD+) gamma

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq, Jul 2008]

ALDH8A1 Gene

aldehyde dehydrogenase 8 family, member A1

This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]

LOC390332 Gene

retinol dehydrogenase 16 (all-trans) pseudogene

NDUFB9 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa

NDUFB8 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa

NDUFB7 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It is located at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]

NDUFB6 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jan 2011]

NDUFB5 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

NDUFB4 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa

This gene encodes a non-catalytic subunit of the multisubunit NADH:ubiquinone oxidoreductase, the first enzyme complex in the mitochondrial electron transport chain (complex I). Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to ubiquinone. [provided by RefSeq, Dec 2009]

NDUFB3 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]

NDUFB2 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008]

NDUFB1 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa

GAPDHP68 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 68

MTHFD2L Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like

LOC642502 Gene

succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa pseudogene

LOC100422348 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

LOC100422346 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

LOC100422347 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

LDHC Gene

lactate dehydrogenase C

Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region. [provided by RefSeq, Jul 2008]

CHDH Gene

choline dehydrogenase

The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date. [provided by RefSeq, Dec 2010]

PGDP1 Gene

phosphogluconate dehydrogenase pseudogene 1

ADH7 Gene

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

ADH6 Gene

alcohol dehydrogenase 6 (class V)

This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ADH5 Gene

alcohol dehydrogenase 5 (class III), chi polypeptide

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]

ADH4 Gene

alcohol dehydrogenase 4 (class II), pi polypeptide

This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008]

MDH1B Gene

malate dehydrogenase 1B, NAD (soluble)

LOC100420746 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 pseudogene

NDUFV2 Gene

NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]

IVD Gene

isovaleryl-CoA dehydrogenase

Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

SDHCP1 Gene

succinate dehydrogenase complex, subunit C pseudogene 1

SDHCP2 Gene

succinate dehydrogenase complex, subunit C pseudogene 2

SDHCP3 Gene

succinate dehydrogenase complex, subunit C pseudogene 3

SDHCP4 Gene

succinate dehydrogenase complex, subunit C pseudogene 4

GPD1L Gene

glycerol-3-phosphate dehydrogenase 1-like

The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010]

GAPDHP75 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 75

GAPDHP74 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 74

GAPDHP71 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 71

GAPDHP70 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 70

GAPDHP73 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 73

GAPDHP72 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 72

PDK1P1 Gene

pyruvate dehydrogenase kinase, isozyme 1 pseudogene 1

G6PD Gene

glucose-6-phosphate dehydrogenase

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

LDHBP1 Gene

lactate dehydrogenase B pseudogene 1

LDHBP2 Gene

lactate dehydrogenase B pseudogene 2

LDHBP3 Gene

lactate dehydrogenase B pseudogene 3

NQO2 Gene

NAD(P)H dehydrogenase, quinone 2

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

NQO1 Gene

NAD(P)H dehydrogenase, quinone 1

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

ALDH7A1P1 Gene

aldehyde dehydrogenase 7 family, member A1 pseudogene 1

ALDH7A1P3 Gene

aldehyde dehydrogenase 7 family, member A1 pseudogene 3

ALDH7A1P2 Gene

aldehyde dehydrogenase 7 family, member A1 pseudogene 2

ALDH7A1P4 Gene

aldehyde dehydrogenase 7 family, member A1 pseudogene 4

LOC645397 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like pseudogene

GAPDH Gene

glyceraldehyde-3-phosphate dehydrogenase

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

RDH14 Gene

retinol dehydrogenase 14 (all-trans/9-cis/11-cis)

RDH11 Gene

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011]

RDH12 Gene

retinol dehydrogenase 12 (all-trans/9-cis/11-cis)

The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). [provided by RefSeq, Jul 2008]

PRODH Gene

proline dehydrogenase (oxidase) 1

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

HPGD Gene

hydroxyprostaglandin dehydrogenase 15-(NAD)

This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

GAPDHP65 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 65

NDUFB3P2 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa pseudogene 2

NDUFB3P3 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa pseudogene 3

NDUFB3P1 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa pseudogene 1

NDUFB3P4 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa pseudogene 4

PDHA1P1 Gene

pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene 1

SARDH Gene

sarcosine dehydrogenase

This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]

LOC100420982 Gene

retinol dehydrogenase 16 (all-trans) pseudogene

ALDH16A1 Gene

aldehyde dehydrogenase 16 family, member A1

This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

NDUFA6 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa

NDUFA7 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa

This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I), which is a multiprotein complex located in the inner mitochondrial membrane. Complex I functions in the transfer of electrons from NADH to the respiratory chain. [provided by RefSeq, Mar 2011]

NDUFA5 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5

This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014]

NDUFA2 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

NDUFA3 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa

NDUFA1 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]

NDUFA8 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa

The protein encoded by this gene belongs to the complex I 19 kDA subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]

NDUFA9 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. A pseudogene has been identified on chromosome 12. [provided by RefSeq, May 2010]

HIBADH Gene

3-hydroxyisobutyrate dehydrogenase

This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011]

LOC102724070 Gene

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 pseudogene

SDR42E1P1 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene 1

D2HGDH Gene

D-2-hydroxyglutarate dehydrogenase

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. [provided by RefSeq, Jul 2008]

MTHFD1L Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

LOC100130783 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 pseudogene

LOC100421317 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC100421314 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC283922 Gene

pyruvate dehydrogenase phosphatase regulatory subunit pseudogene

ADH1C Gene

alcohol dehydrogenase 1C (class I), gamma polypeptide

This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]

ADH1B Gene

alcohol dehydrogenase 1B (class I), beta polypeptide

The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

ADH1A Gene

alcohol dehydrogenase 1A (class I), alpha polypeptide

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

LOC729999 Gene

glycerol-3-phosphate dehydrogenase 2 (mitochondrial) pseudogene

LOC100422431 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa pseudogene

NDUFA5P5 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 5

NDUFA5P4 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 4

NDUFA5P6 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 6

NDUFA5P1 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 1

NDUFA5P3 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 3

LOC644051 Gene

isocitrate dehydrogenase pseudogene

DPYD Gene

dihydropyrimidine dehydrogenase

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

HSD3B7 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

HSD3B1 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

HSD3B2 Gene

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

DLD Gene

dihydrolipoamide dehydrogenase

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

LOC100287928 Gene

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit pseudogene

IMPDH1P9 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 9

IMPDH1P8 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 8

IMPDH1P3 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 3

IMPDH1P2 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 2

IMPDH1P1 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 1

IMPDH1P6 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 6

IMPDH1P4 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 4

HADHB Gene

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit

This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

HADHA Gene

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit

This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq, Jul 2008]

EHHADH Gene

enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase

The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

ZADH2 Gene

zinc binding alcohol dehydrogenase domain containing 2

LOC100421261 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC100421264 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC100190934 Gene

alcohol dehydrogenase 5 (class III), chi polypeptide pseudogene

MDH2 Gene

malate dehydrogenase 2, NAD (mitochondrial)

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

MDH1 Gene

malate dehydrogenase 1, NAD (soluble)

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Nov 2010]

SORD2P Gene

sorbitol dehydrogenase 2, pseudogene

GAPDHP48 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 48

GAPDHP49 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 49

GAPDHP44 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 44

GAPDHP45 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 45

GAPDHP46 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 46

GAPDHP47 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 47

GAPDHP40 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 40

GAPDHP41 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 41

GAPDHP42 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 42

GAPDHP43 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 43

LOC220729 Gene

succinate dehydrogenase complex, subunit A, flavoprotein (Fp) pseudogene

PRODH2 Gene

proline dehydrogenase (oxidase) 2

The protein encoded by this gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme which catalyzes the first step in proline catabolism. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]

GLUD2 Gene

glutamate dehydrogenase 2

The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010]

GLUD1 Gene

glutamate dehydrogenase 1

This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009]

LDHAP7 Gene

lactate dehydrogenase A pseudogene 7

LDHAP5 Gene

lactate dehydrogenase A pseudogene 5

LDHAP4 Gene

lactate dehydrogenase A pseudogene 4

LDHAP3 Gene

lactate dehydrogenase A pseudogene 3

LDHAP2 Gene

lactate dehydrogenase A pseudogene 2

LDHAP1 Gene

lactate dehydrogenase A pseudogene 1

GLUD1P5 Gene

glutamate dehydrogenase 1 pseudogene 5

GLUD1P3 Gene

glutamate dehydrogenase 1 pseudogene 3

GLUD1P8 Gene

glutamate dehydrogenase 1 pseudogene 8

GLUD1P9 Gene

glutamate dehydrogenase 1 pseudogene 9

XDH Gene

xanthine dehydrogenase

Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]

DHDH Gene

dihydrodiol dehydrogenase (dimeric)

This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008]

GCDH Gene

glutaryl-CoA dehydrogenase

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]

NDUFAF4P4 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 pseudogene 4

NDUFAF4P3 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 pseudogene 3

NDUFAF4P2 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 pseudogene 2

NDUFAF4P1 Gene

NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 pseudogene 1

DMGDH Gene

dimethylglycine dehydrogenase

This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

ASPDH Gene

aspartate dehydrogenase domain containing

NDUFS5P3 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 3

NDUFS5P2 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 2

NDUFS5P7 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 7

NDUFS5P5 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 5

NDUFS5P4 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 4

LOC390586 Gene

hydroxyacyl-CoA dehydrogenase pseudogene

ADHFE1 Gene

alcohol dehydrogenase, iron containing, 1

The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).[supplied by OMIM, Mar 2008]

SDR9C7 Gene

short chain dehydrogenase/reductase family 9C, member 7

This gene encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities. [provided by RefSeq, Apr 2010]

IDH2 Gene

isocitrate dehydrogenase 2 (NADP+), mitochondrial

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

IDH1 Gene

isocitrate dehydrogenase 1 (NADP+), soluble

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]

NDUFA9P1 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, pseudogene 1

OGDHL Gene

oxoglutarate dehydrogenase-like

SDHDP7 Gene

succinate dehydrogenase complex, subunit D, integral membrane protein pseudogene 7

SDHDP6 Gene

succinate dehydrogenase complex, subunit D, integral membrane protein pseudogene 6

SDHDP5 Gene

succinate dehydrogenase complex, subunit D, integral membrane protein pseudogene 5

SDHDP4 Gene

succinate dehydrogenase complex, subunit D, integral membrane protein pseudogene 4

SDHDP3 Gene

succinate dehydrogenase complex, subunit D, integral membrane protein pseudogene 3

SDHDP2 Gene

succinate dehydrogenase complex, subunit D, integral membrane protein pseudogene 2

SDHDP1 Gene

succinate dehydrogenase complex, subunit D, integral membrane protein pseudogene 1

LOC392477 Gene

malate dehydrogenase 1, NAD (soluble) pseudogene

SCCPDH Gene

saccharopine dehydrogenase (putative)

IMPDH2 Gene

IMP (inosine 5'-monophosphate) dehydrogenase 2

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]

NDUFA5P12 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 12

ALDH4A1 Gene

aldehyde dehydrogenase 4 family, member A1

This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2009]

ALDH7A1 Gene

aldehyde dehydrogenase 7 family, member A1

The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]

LOC102724853 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene

LOC644203 Gene

glutaryl-CoA dehydrogenase, mitochondrial-like

SDHAF1 Gene

succinate dehydrogenase complex assembly factor 1

The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).[provided by RefSeq, Mar 2010]

SDHAF2 Gene

succinate dehydrogenase complex assembly factor 2

This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.[provided by RefSeq, Jul 2010]

SDHAF3 Gene

succinate dehydrogenase complex assembly factor 3

SDHAF4 Gene

succinate dehydrogenase complex assembly factor 4

NDUFA5P9 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 9

LDHD Gene

lactate dehydrogenase D

The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

LDHA Gene

lactate dehydrogenase A

The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]

LDHB Gene

lactate dehydrogenase B

This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2010]

NDUFA4P1 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa, pseudogene 1

NDUFA4P2 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa, pseudogene 2

NDUFS5P1 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 1

IMPDH1P11 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 11

IMPDH1P10 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 10

NDUFA4L2 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2

NDUFS1 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

NDUFS2 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

NDUFS3 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

NDUFS4 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq, Jul 2008]

NDUFS5 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)

This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17. [provided by RefSeq, May 2010]

NDUFS6 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)

This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]

NDUFS7 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]

NDUFS8 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]

GAPDHP17 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 17

GAPDHP16 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 16

GAPDHP14 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 14

GAPDHP19 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 19

LOC100288420 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa pseudogene

MTHFD1 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008]

GAPDHP59 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 59

GAPDHP58 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 58

GAPDHP56 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 56

MT-ND4L Gene

NADH dehydrogenase, subunit 4L (complex I)

NDUFA10 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa

The protein encoded by this gene belongs to the complex I 42kDA subunit family. Mammalian complex I is the first enzyme complex in the electron transport chain of mitochondria. It is composed of 45 different subunits. This protein is a component of the hydrophobic protein fraction and has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. [provided by RefSeq, Jul 2008]

IDH3A Gene

isocitrate dehydrogenase 3 (NAD+) alpha

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]

LOC100288337 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa pseudogene

GAPDHS Gene

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]

LOC100128939 Gene

pyruvate dehydrogenase kinase, isozyme 3 pseudogene

NSDHL Gene

NAD(P) dependent steroid dehydrogenase-like

The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]

LDHAL6B Gene

lactate dehydrogenase A-like 6B

LDHAL6A Gene

lactate dehydrogenase A-like 6A

IMPDH1P7 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 7

IMPDH1P5 Gene

IMP (inosine monophosphate) dehydrogenase 1 pseudogene 5

SORDL Gene

sorbitol dehydrogenase-like

LOC103091863 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene

LDHAL6DP Gene

lactate dehydrogenase A-like 6D, pseudogene

MTHFD1P1 Gene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 pseudogene 1

LOC100421335 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

PGD Gene

phosphogluconate dehydrogenase

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]

NDUFC1 Gene

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

NDUFC2 Gene

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa

LOC102724788 Gene

proline dehydrogenase 1, mitochondrial

GAPDHP15 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 15

NDUFAB1 Gene

NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa

L2HGDH Gene

L-2-hydroxyglutarate dehydrogenase

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation. [provided by RefSeq, Jul 2008]

LOC100422339 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

AASDHPPT Gene

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]

BCKDHB Gene

branched chain keto acid dehydrogenase E1, beta polypeptide

Branched-chain keto acid dehydrogenase is a multienzyme complex associated with the inner membrane of mitochondria, and functions in the catabolism of branched-chain amino acids. The complex consists of multiple copies of 3 components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). This gene encodes the E1 beta subunit, and mutations therein have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation, and feeding problems. Alternative splicing at this locus results in transcript variants with different 3' non-coding regions, but encoding the same isoform. [provided by RefSeq, Jul 2008]

BCKDHA Gene

branched chain keto acid dehydrogenase E1, alpha polypeptide

The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

SDR16C5 Gene

short chain dehydrogenase/reductase family 16C, member 5

RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).[supplied by OMIM, Mar 2008]

HADH Gene

hydroxyacyl-CoA dehydrogenase

This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]

ALDH9A1 Gene

aldehyde dehydrogenase 9 family, member A1

This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]

NDUFV3 Gene

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa

The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

NDUFV1 Gene

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

GAPDHP62 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 62

GAPDHP63 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 63

GAPDHP60 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 60

GAPDHP61 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 61

GAPDHP66 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 66

GAPDHP67 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 67

GAPDHP64 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene 64

GAPDHP69 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 69

NDUFA12P1 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 pseudogene 1

SDHAP2 Gene

succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2

SDHAP3 Gene

succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3

SDHAP1 Gene

succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1

RDH8 Gene

retinol dehydrogenase 8 (all-trans)

This gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [provided by RefSeq, Feb 2014]

RDH5 Gene

retinol dehydrogenase 5 (11-cis/9-cis)

This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]

NDUFB8P2 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, pseudogene 2

LDHAL6CP Gene

lactate dehydrogenase A-like 6C, pseudogene

NDUFB1P1 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1 pseudogene 1

NDUFB11 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa

NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 [PubMed 12381726]).[supplied by OMIM, Feb 2009]

NDUFB10 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa

LOC100421322 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

GAPDHP27 Gene

glyceraldehyde 3 phosphate dehydrogenase pseudogene 27

LOC102724866 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene

LOC100421265 Gene

glyceraldehyde-3-phosphate dehydrogenase pseudogene

LOC402175 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa pseudogene

SDR39U1 Gene

short chain dehydrogenase/reductase family 39U, member 1

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) superfamily, which includes both classical and extended types. The encoded protein represents an extended type, with similarity to epimerases. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]

ETFDH Gene

electron-transferring-flavoprotein dehydrogenase

This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed. [provided by RefSeq, Aug 2013]

LOC105371187 Gene

putative short-chain dehydrogenase/reductase family 42E member 2

17-Hydroxysteroid Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease 17-Hydroxysteroid Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

3 beta-Hydroxysteroid dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the 3 beta-Hydroxysteroid dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Deficiency of (R)-20-hydroxysteroid dehydrogenase Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Deficiency of (R)-20-hydroxysteroid dehydrogenase phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

3b-Hydroxysteroid Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease 3b-Hydroxysteroid Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

3-beta-hydroxysteroid dehydrogenase, type ii, deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the 3-beta-hydroxysteroid dehydrogenase, type ii, deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

17-beta-hydroxysteroid dehydrogenase x deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the 17-beta-hydroxysteroid dehydrogenase x deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

11-beta-hydroxysteroid dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the 11-beta-hydroxysteroid dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

11-beta-hydroxysteroid dehydrogenase [nad(p)] activity Gene Set

From GO Molecular Function Annotations

genes performing the 11-beta-hydroxysteroid dehydrogenase [nad(p)] activity molecular function from the curated GO Molecular Function Annotations dataset.

17-beta-hydroxysteroid dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the 17-beta-hydroxysteroid dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

3-beta hydroxysteroid dehydrogenase/isomerase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-beta hydroxysteroid dehydrogenase/isomerase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

hydroxysteroid Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hydroxysteroid in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

factor v deficiency; hypoprothrombinemias; protein c deficiency; protein s deficiency; pulmonary embolism; thrombophilia; venous thrombosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease factor v deficiency; hypoprothrombinemias; protein c deficiency; protein s deficiency; pulmonary embolism; thrombophilia; venous thrombosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

antithrombin iii deficiency; gastrointestinal hemorrhage; protein c deficiency; protein s deficiency; splenomegaly; thrombophilia; turner syndrome; venous thrombosis; xo syndrome Gene Set

From GAD Gene-Disease Associations

genes associated with the disease antithrombin iii deficiency; gastrointestinal hemorrhage; protein c deficiency; protein s deficiency; splenomegaly; thrombophilia; turner syndrome; venous thrombosis; xo syndrome in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

activated protein c resistance; antithrombin iii deficiency; pregnancy complications, hematologic; protein c deficiency; protein s deficiency; puerperal disorders; pulmonary embolism; pulmonary embolisms; thrombophilia; venous thrombosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease activated protein c resistance; antithrombin iii deficiency; pregnancy complications, hematologic; protein c deficiency; protein s deficiency; puerperal disorders; pulmonary embolism; pulmonary embolisms; thrombophilia; venous thrombosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Phosphoglycerate dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Phosphoglycerate dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Pyruvate dehydrogenase E2 deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Pyruvate dehydrogenase E2 deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Testosterone 17-beta-dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Testosterone 17-beta-dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Acyl-CoA dehydrogenase family, member 9, deficiency of Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Acyl-CoA dehydrogenase family, member 9, deficiency of phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Deficiency of 2-methylbutyryl-CoA dehydrogenase Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Deficiency of 2-methylbutyryl-CoA dehydrogenase phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Deficiency of isobutyryl-CoA dehydrogenase Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Deficiency of isobutyryl-CoA dehydrogenase phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Lactate dehydrogenase b deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Lactate dehydrogenase b deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Deficiency of 3-hydroxyacyl-CoA dehydrogenase Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Deficiency of 3-hydroxyacyl-CoA dehydrogenase phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Deficiency of butyryl-CoA dehydrogenase Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Deficiency of butyryl-CoA dehydrogenase phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Pyruvate dehydrogenase phosphatase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Pyruvate dehydrogenase phosphatase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Pyruvate dehydrogenase lipoic acid synthetase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Pyruvate dehydrogenase lipoic acid synthetase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Sarcosine dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Sarcosine dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Branched-chain ketoacid dehydrogenase kinase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Branched-chain ketoacid dehydrogenase kinase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Medium-chain acyl-coenzyme A dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Medium-chain acyl-coenzyme A dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Pyruvate dehydrogenase E3-binding protein deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Pyruvate dehydrogenase E3-binding protein deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Very long chain acyl-CoA dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Very long chain acyl-CoA dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Dimethylglycine dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Dimethylglycine dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Pyruvate dehydrogenase E1-alpha deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Pyruvate dehydrogenase E1-alpha deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Isovaleryl-CoA dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Isovaleryl-CoA dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Pyruvate dehydrogenase E1-beta deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Pyruvate dehydrogenase E1-beta deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Succinate-semialdehyde dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Succinate-semialdehyde dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Proline dehydrogenase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Proline dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Pyruvate dehydrogenase phosphatase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Pyruvate dehydrogenase phosphatase deficiency from the curated CTD Gene-Disease Associations dataset.

LONG-CHAIN 3-HYDROXYACYL-CoA DEHYDROGENASE DEFICIENCY Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease LONG-CHAIN 3-HYDROXYACYL-CoA DEHYDROGENASE DEFICIENCY from the curated CTD Gene-Disease Associations dataset.

Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of from the curated CTD Gene-Disease Associations dataset.

3-Hydroxyacyl-CoA Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease 3-Hydroxyacyl-CoA Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

Multiple Acyl Coenzyme A Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Multiple Acyl Coenzyme A Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

Pyruvate Dehydrogenase E2 Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Pyruvate Dehydrogenase E2 Deficiency from the curated CTD Gene-Disease Associations dataset.

Phosphoglycerate Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Phosphoglycerate Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

Pyruvate Dehydrogenase Complex Deficiency Disease Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Pyruvate Dehydrogenase Complex Deficiency Disease from the curated CTD Gene-Disease Associations dataset.

Dimethylglycine Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Dimethylglycine Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

Hydroxyacyl-CoA Dehydrogenase, Type 2, Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Hydroxyacyl-CoA Dehydrogenase, Type 2, Deficiency from the curated CTD Gene-Disease Associations dataset.

2-Methylbutyryl-CoA Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease 2-Methylbutyryl-CoA Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

Isobutyryl-CoA dehydrogenase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Isobutyryl-CoA dehydrogenase deficiency from the curated CTD Gene-Disease Associations dataset.

Dihydropyrimidine Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Dihydropyrimidine Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

Lactate dehydrogenase deficiency type A Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Lactate dehydrogenase deficiency type A from the curated CTD Gene-Disease Associations dataset.

Pyruvate Dehydrogenase E3-Binding Protein Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Pyruvate Dehydrogenase E3-Binding Protein Deficiency from the curated CTD Gene-Disease Associations dataset.

succinic semialdehyde dehydrogenase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease succinic semialdehyde dehydrogenase deficiency from the curated CTD Gene-Disease Associations dataset.

Alpha-ketoglutarate dehydrogenase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Alpha-ketoglutarate dehydrogenase deficiency from the curated CTD Gene-Disease Associations dataset.

Medium chain acyl CoA dehydrogenase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Medium chain acyl CoA dehydrogenase deficiency from the curated CTD Gene-Disease Associations dataset.

Short chain Acyl CoA dehydrogenase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Short chain Acyl CoA dehydrogenase deficiency from the curated CTD Gene-Disease Associations dataset.

Glucosephosphate Dehydrogenase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Glucosephosphate Dehydrogenase Deficiency from the curated CTD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency Gene Set

From DISEASES Curated Gene-Disease Assocation Evidence Scores

genes involed in the disease glucosephosphate dehydrogenase deficiency from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

dihydropyrimidine dehydrogenase deficiency Gene Set

From DISEASES Curated Gene-Disease Assocation Evidence Scores

genes involed in the disease dihydropyrimidine dehydrogenase deficiency from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

succinic semialdehyde dehydrogenase deficiency Gene Set

From DISEASES Curated Gene-Disease Assocation Evidence Scores

genes involed in the disease succinic semialdehyde dehydrogenase deficiency from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

succinic semialdehyde dehydrogenase deficiency Gene Set

From DISEASES Text-mining Gene-Disease Assocation Evidence Scores

genes co-occuring with the disease succinic semialdehyde dehydrogenase deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

glucosephosphate dehydrogenase deficiency Gene Set

From DISEASES Text-mining Gene-Disease Assocation Evidence Scores

genes co-occuring with the disease glucosephosphate dehydrogenase deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

dihydropyrimidine dehydrogenase deficiency Gene Set

From DISEASES Text-mining Gene-Disease Assocation Evidence Scores

genes co-occuring with the disease dihydropyrimidine dehydrogenase deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

glucosephosphate dehydrogenase deficiency; hyperbilirubinemia, neonatal Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency; hyperbilirubinemia, neonatal in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

alpha-thalassemia; anemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait Gene Set

From GAD Gene-Disease Associations

genes associated with the disease alpha-thalassemia; anemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; stroke Gene Set

From GAD Gene-Disease Associations

genes associated with the disease alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; stroke in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

medium-chain acyl-coa dehydrogenase deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease medium-chain acyl-coa dehydrogenase deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

disorder of muscle, unspec; lipidoses; lipoidosis; multiple acyl coenzyme a dehydrogenase deficiency; muscular diseases Gene Set

From GAD Gene-Disease Associations

genes associated with the disease disorder of muscle, unspec; lipidoses; lipoidosis; multiple acyl coenzyme a dehydrogenase deficiency; muscular diseases in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

medium-chain acyl-coa dehydrogenase (mcad) deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease medium-chain acyl-coa dehydrogenase (mcad) deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

alpha thalassemia; alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; sickle cell anemia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease alpha thalassemia; alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; sickle cell anemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

beta thalassemia; beta-thalassemia; glucosephosphate dehydrogenase deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease beta thalassemia; beta-thalassemia; glucosephosphate dehydrogenase deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

encephalitis; glucosephosphate dehydrogenase deficiency; jaundice, neonatal; neonatal jaundice Gene Set

From GAD Gene-Disease Associations

genes associated with the disease encephalitis; glucosephosphate dehydrogenase deficiency; jaundice, neonatal; neonatal jaundice in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency; hemolysis; jaundice, neonatal; neonatal jaundice Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency; hemolysis; jaundice, neonatal; neonatal jaundice in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency; hyperbilirubinemia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency; hyperbilirubinemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anemia, sickle cell; glucosephosphate dehydrogenase deficiency; sickle cell anemia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anemia, sickle cell; glucosephosphate dehydrogenase deficiency; sickle cell anemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

alpha-thalassemia; beta-thalassemia; glucosephosphate dehydrogenase deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease alpha-thalassemia; beta-thalassemia; glucosephosphate dehydrogenase deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dihydropyrimidine dehydrogenase deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dihydropyrimidine dehydrogenase deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

alpha-thalassemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait Gene Set

From GAD Gene-Disease Associations

genes associated with the disease alpha-thalassemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

acyl-coa dehydrogenase (scad) deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease acyl-coa dehydrogenase (scad) deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

favism; glucosephosphate dehydrogenase deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease favism; glucosephosphate dehydrogenase deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency; hemoglobinuria; syndrome Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency; hemoglobinuria; syndrome in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency; malaria, vivax Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency; malaria, vivax in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency; malaria, falciparum Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency; malaria, falciparum in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

favism; glucosephosphate dehydrogenase deficiency; hemolysis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease favism; glucosephosphate dehydrogenase deficiency; hemolysis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucosephosphate dehydrogenase deficiency; malaria Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucosephosphate dehydrogenase deficiency; malaria in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

long chain 3 hydroxyacyl coa dehydrogenase deficiency Gene Set

From HPO Gene-Disease Associations

genes associated with the long chain 3 hydroxyacyl coa dehydrogenase deficiency phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Multiple Acyl Coenzyme A Dehydrogenase Deficiency Gene Set

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Multiple Acyl Coenzyme A Dehydrogenase Deficiency phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Dihydropyrimidine Dehydrogenase Deficiency Gene Set

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Dihydropyrimidine Dehydrogenase Deficiency phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Glucosephosphate Dehydrogenase Deficiency Gene Set

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Glucosephosphate Dehydrogenase Deficiency phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

dimethylglycine dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the dimethylglycine dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

pyruvate dehydrogenase lipoic acid synthetase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the pyruvate dehydrogenase lipoic acid synthetase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

pyruvate dehydrogenase e1-beta deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the pyruvate dehydrogenase e1-beta deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

dihydrolipoamide dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the dihydrolipoamide dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

3-hydroxyacyl-coa dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the 3-hydroxyacyl-coa dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

pyruvate dehydrogenase phosphatase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the pyruvate dehydrogenase phosphatase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

phosphoglycerate dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the phosphoglycerate dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

isobutyryl-coa dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the isobutyryl-coa dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

acyl-coa dehydrogenase, medium chain, deficiency of Gene Set

From OMIM Gene-Disease Associations

genes associated with the acyl-coa dehydrogenase, medium chain, deficiency of phenotype from the curated OMIM Gene-Disease Associations dataset.

lactate dehydrogenase-b deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the lactate dehydrogenase-b deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

pyruvate dehydrogenase e1-alpha deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the pyruvate dehydrogenase e1-alpha deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

alpha-ketoglutarate dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the alpha-ketoglutarate dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

acyl-coa dehydrogenase, short-chain, deficiency of Gene Set

From OMIM Gene-Disease Associations

genes associated with the acyl-coa dehydrogenase, short-chain, deficiency of phenotype from the curated OMIM Gene-Disease Associations dataset.

dihydropyrimidine dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the dihydropyrimidine dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

methylmalonate semialdehyde dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the methylmalonate semialdehyde dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

succinic semialdehyde dehydrogenase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the succinic semialdehyde dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

branched-chain ketoacid dehydrogenase kinase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the branched-chain ketoacid dehydrogenase kinase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

pyruvate dehydrogenase e2 deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the pyruvate dehydrogenase e2 deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

Neuraminidase deficiency with beta-galactosidase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Neuraminidase deficiency with beta-galactosidase deficiency from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 1;MC5DN1 MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, ATPAF2 TYPE Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 1;MC5DN1 MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, ATPAF2 TYPE from the curated CTD Gene-Disease Associations dataset.

eclampsia; pre-eclampsia; protein c deficiency; protein s deficiency; thrombophilia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease eclampsia; pre-eclampsia; protein c deficiency; protein s deficiency; thrombophilia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

blood coagulation disorders, inherited; protein c deficiency; protein s deficiency; thrombophilia; venous thrombosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease blood coagulation disorders, inherited; protein c deficiency; protein s deficiency; thrombophilia; venous thrombosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

blood coagulation disorders; protein c deficiency; protein s deficiency; pulmonary embolism; pulmonary embolisms; thrombosis; venous thrombosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease blood coagulation disorders; protein c deficiency; protein s deficiency; pulmonary embolism; pulmonary embolisms; thrombosis; venous thrombosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anemia, iron-deficiency; iron deficiency anaemia; tuberculosis, pulmonary Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anemia, iron-deficiency; iron deficiency anaemia; tuberculosis, pulmonary in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

folic acid deficiency; fractures, bone; osteoporosis, postmenopausal; riboflavin deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease folic acid deficiency; fractures, bone; osteoporosis, postmenopausal; riboflavin deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

activated protein c resistance; blood coagulation disorders; liver diseases; protein c deficiency; protein s deficiency; thrombosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease activated protein c resistance; blood coagulation disorders; liver diseases; protein c deficiency; protein s deficiency; thrombosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anemia, iron-deficiency; hemochromatosis; iron deficiency anaemia; iron overload Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anemia, iron-deficiency; hemochromatosis; iron deficiency anaemia; iron overload in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

choline deficiency; dna damage; folic acid deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease choline deficiency; dna damage; folic acid deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

folic acid deficiency; pregnancy complications; prenatal exposure delayed effects; psychomotor disorders; vitamin b 12 deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease folic acid deficiency; pregnancy complications; prenatal exposure delayed effects; psychomotor disorders; vitamin b 12 deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anemia, iron-deficiency; beta thalassemia; beta-thalassemia; iron deficiency anaemia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anemia, iron-deficiency; beta thalassemia; beta-thalassemia; iron deficiency anaemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anemia, iron-deficiency; iron deficiency anaemia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anemia, iron-deficiency; iron deficiency anaemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

protein c deficiency; protein s deficiency; venous thrombosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease protein c deficiency; protein s deficiency; venous thrombosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

folic acid deficiency; hyperhomocysteinemia; thromboembolism; venous insufficiency; vitamin b 12 deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease folic acid deficiency; hyperhomocysteinemia; thromboembolism; venous insufficiency; vitamin b 12 deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anemia, iron-deficiency; iron deficiency anaemia; iron overload Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anemia, iron-deficiency; iron deficiency anaemia; iron overload in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

neoplasms; protein c deficiency; protein s deficiency; venous thromboembolism Gene Set

From GAD Gene-Disease Associations

genes associated with the disease neoplasms; protein c deficiency; protein s deficiency; venous thromboembolism in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anemia, iron-deficiency; hemochromatosis; iron deficiency anaemia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anemia, iron-deficiency; hemochromatosis; iron deficiency anaemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

chronic renal failure; folic acid deficiency; hyperhomocysteinemia; kidney failure, chronic; vitamin b 12 deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease chronic renal failure; folic acid deficiency; hyperhomocysteinemia; kidney failure, chronic; vitamin b 12 deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) Gene Set

From Reactome Pathways

proteins participating in the Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) pathway from the Reactome Pathways dataset.

Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) Gene Set

From Reactome Pathways

proteins participating in the Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) pathway from the Reactome Pathways dataset.

Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Gene Set

From Reactome Pathways

proteins participating in the Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) pathway from the Reactome Pathways dataset.

oxoglutarate dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the oxoglutarate dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

mitochondrial alpha-ketoglutarate dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mitochondrial alpha-ketoglutarate dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

succinate dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the succinate dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

nadh dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the nadh dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

succinate dehydrogenase complex (ubiquinone) Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the succinate dehydrogenase complex (ubiquinone) cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

pyruvate dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the pyruvate dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dihydrolipoyl dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dihydrolipoyl dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

glycerol-3-phosphate dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the glycerol-3-phosphate dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

mitochondrial pyruvate dehydrogenase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mitochondrial pyruvate dehydrogenase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

oxoglutarate dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the oxoglutarate dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

mitochondrial alpha-ketoglutarate dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mitochondrial alpha-ketoglutarate dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

formate dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the formate dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

succinate dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the succinate dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

succinate dehydrogenase complex (ubiquinone) Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the succinate dehydrogenase complex (ubiquinone) cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

pyruvate dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the pyruvate dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

acetyl-coa decarbonylase/synthase-carbon monoxide dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the acetyl-coa decarbonylase/synthase-carbon monoxide dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

plastid pyruvate dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the plastid pyruvate dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dihydrolipoyl dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dihydrolipoyl dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nadh dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nadh dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

mitochondrial pyruvate dehydrogenase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mitochondrial pyruvate dehydrogenase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Isocitrate dehydrogenase, cytoplasmic Gene Set

From CORUM Protein Complexes

proteins in the Isocitrate dehydrogenase, cytoplasmic protein complex from the CORUM Protein Complexes dataset.

Succinate dehydrogenase complex II (EC 1.3.5.1), mitochondrial Gene Set

From CORUM Protein Complexes

proteins in the Succinate dehydrogenase complex II (EC 1.3.5.1), mitochondrial protein complex from the CORUM Protein Complexes dataset.

L-Lactate Dehydrogenase Gene Set

From dbGAP Gene-Trait Associations

genes associated with the trait L-Lactate Dehydrogenase in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

neural tube defects; dihydropyrimidine dehydrogenase Gene Set

From GAD Gene-Disease Associations

genes associated with the disease neural tube defects; dihydropyrimidine dehydrogenase in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

undetectable glucose-6-phosphate dehydrogenase enzyme activity Gene Set

From GAD Gene-Disease Associations

genes associated with the disease undetectable glucose-6-phosphate dehydrogenase enzyme activity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

l-lactate dehydrogenase Gene Set

From GAD Gene-Disease Associations

genes associated with the disease l-lactate dehydrogenase in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dehydrogenase Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dehydrogenase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

fatty acid beta-oxidation using acyl-coa dehydrogenase Gene Set

From GO Biological Process Annotations

genes participating in the fatty acid beta-oxidation using acyl-coa dehydrogenase biological process from the curated GO Biological Process Annotations dataset.

nadh dehydrogenase complex assembly Gene Set

From GO Biological Process Annotations

genes participating in the nadh dehydrogenase complex assembly biological process from the curated GO Biological Process Annotations dataset.

oxoglutarate dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the oxoglutarate dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

mitochondrial alpha-ketoglutarate dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the mitochondrial alpha-ketoglutarate dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

succinate dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the succinate dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

succinate dehydrogenase complex (ubiquinone) Gene Set

From GO Cellular Component Annotations

proteins localized to the succinate dehydrogenase complex (ubiquinone) cellular component from the curated GO Cellular Component Annotations dataset.

nadh dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the nadh dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

dihydrolipoyl dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the dihydrolipoyl dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

glycerol-3-phosphate dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the glycerol-3-phosphate dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

pyruvate dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the pyruvate dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

mitochondrial pyruvate dehydrogenase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the mitochondrial pyruvate dehydrogenase complex cellular component from the curated GO Cellular Component Annotations dataset.

succinate-semialdehyde dehydrogenase binding Gene Set

From GO Molecular Function Annotations

genes performing the succinate-semialdehyde dehydrogenase binding molecular function from the curated GO Molecular Function Annotations dataset.

glutathione dehydrogenase (ascorbate) activity Gene Set

From GO Molecular Function Annotations

genes performing the glutathione dehydrogenase (ascorbate) activity molecular function from the curated GO Molecular Function Annotations dataset.

methylenetetrahydrofolate dehydrogenase [nad(p)+] activity Gene Set

From GO Molecular Function Annotations

genes performing the methylenetetrahydrofolate dehydrogenase [nad(p)+] activity molecular function from the curated GO Molecular Function Annotations dataset.

methylmalonate-semialdehyde dehydrogenase (acylating) activity Gene Set

From GO Molecular Function Annotations

genes performing the methylmalonate-semialdehyde dehydrogenase (acylating) activity molecular function from the curated GO Molecular Function Annotations dataset.

l-gulonate 3-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the l-gulonate 3-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

retinal dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the retinal dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

thiomorpholine-carboxylate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the thiomorpholine-carboxylate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

methylenetetrahydrofolate dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the methylenetetrahydrofolate dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

xanthine dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the xanthine dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-hydroxybutyrate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-hydroxybutyrate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

succinate dehydrogenase (ubiquinone) activity Gene Set

From GO Molecular Function Annotations

genes performing the succinate dehydrogenase (ubiquinone) activity molecular function from the curated GO Molecular Function Annotations dataset.

aldehyde dehydrogenase (nad) activity Gene Set

From GO Molecular Function Annotations

genes performing the aldehyde dehydrogenase (nad) activity molecular function from the curated GO Molecular Function Annotations dataset.

udp-glucose 6-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the udp-glucose 6-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

glycerol-3-phosphate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the glycerol-3-phosphate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

proline dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the proline dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

acyl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the acyl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

l-lactate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the l-lactate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

succinate-semialdehyde dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the succinate-semialdehyde dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

nad(p)h dehydrogenase (quinone) activity Gene Set

From GO Molecular Function Annotations

genes performing the nad(p)h dehydrogenase (quinone) activity molecular function from the curated GO Molecular Function Annotations dataset.

phosphoglycerate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the phosphoglycerate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

s-(hydroxymethyl)glutathione dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the s-(hydroxymethyl)glutathione dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

1-pyrroline-5-carboxylate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 1-pyrroline-5-carboxylate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-hydroxyacyl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-hydroxyacyl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

l-malate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the l-malate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

pyruvate dehydrogenase (acetyl-transferring) activity Gene Set

From GO Molecular Function Annotations

genes performing the pyruvate dehydrogenase (acetyl-transferring) activity molecular function from the curated GO Molecular Function Annotations dataset.

steroid dehydrogenase activity, acting on the ch-oh group of donors, nad or nadp as acceptor Gene Set

From GO Molecular Function Annotations

genes performing the steroid dehydrogenase activity, acting on the ch-oh group of donors, nad or nadp as acceptor molecular function from the curated GO Molecular Function Annotations dataset.

alcohol dehydrogenase [nad(p)+] activity Gene Set

From GO Molecular Function Annotations

genes performing the alcohol dehydrogenase [nad(p)+] activity molecular function from the curated GO Molecular Function Annotations dataset.

sarcosine dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the sarcosine dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

[pyruvate dehydrogenase (lipoamide)] phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the [pyruvate dehydrogenase (lipoamide)] phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

nadh dehydrogenase (quinone) activity Gene Set

From GO Molecular Function Annotations

genes performing the nadh dehydrogenase (quinone) activity molecular function from the curated GO Molecular Function Annotations dataset.

glyceraldehyde-3-phosphate dehydrogenase (nad+) (phosphorylating) activity Gene Set

From GO Molecular Function Annotations

genes performing the glyceraldehyde-3-phosphate dehydrogenase (nad+) (phosphorylating) activity molecular function from the curated GO Molecular Function Annotations dataset.

phosphogluconate dehydrogenase (decarboxylating) activity Gene Set

From GO Molecular Function Annotations

genes performing the phosphogluconate dehydrogenase (decarboxylating) activity molecular function from the curated GO Molecular Function Annotations dataset.

3-beta-hydroxy-delta5-steroid dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-beta-hydroxy-delta5-steroid dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

medium-chain-acyl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the medium-chain-acyl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

isocitrate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the isocitrate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

15-hydroxyprostaglandin dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the 15-hydroxyprostaglandin dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

glucose 1-dehydrogenase [nad(p)] activity Gene Set

From GO Molecular Function Annotations

genes performing the glucose 1-dehydrogenase [nad(p)] activity molecular function from the curated GO Molecular Function Annotations dataset.

alcohol dehydrogenase activity, zinc-dependent Gene Set

From GO Molecular Function Annotations

genes performing the alcohol dehydrogenase activity, zinc-dependent molecular function from the curated GO Molecular Function Annotations dataset.

electron-transferring-flavoprotein dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the electron-transferring-flavoprotein dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

udp-n-acetylmuramate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the udp-n-acetylmuramate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

oxoglutarate dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the oxoglutarate dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

saccharopine dehydrogenase (nad+, l-glutamate-forming) activity Gene Set

From GO Molecular Function Annotations

genes performing the saccharopine dehydrogenase (nad+, l-glutamate-forming) activity molecular function from the curated GO Molecular Function Annotations dataset.

formaldehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the formaldehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

glutaryl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the glutaryl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

glutamate-5-semialdehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the glutamate-5-semialdehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

androsterone dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the androsterone dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

glycine dehydrogenase (decarboxylating) activity Gene Set

From GO Molecular Function Annotations

genes performing the glycine dehydrogenase (decarboxylating) activity molecular function from the curated GO Molecular Function Annotations dataset.

[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

l-iditol 2-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the l-iditol 2-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

betaine-aldehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the betaine-aldehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

glutamate dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the glutamate dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

testosterone 17-beta-dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the testosterone 17-beta-dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

malonate-semialdehyde dehydrogenase (acetylating) activity Gene Set

From GO Molecular Function Annotations

genes performing the malonate-semialdehyde dehydrogenase (acetylating) activity molecular function from the curated GO Molecular Function Annotations dataset.

sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity Gene Set

From GO Molecular Function Annotations

genes performing the sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity molecular function from the curated GO Molecular Function Annotations dataset.

lactate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the lactate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

dihydroorotate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the dihydroorotate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

15-hydroxyprostaglandin-d dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the 15-hydroxyprostaglandin-d dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

alcohol dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the alcohol dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

2-hydroxyglutarate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 2-hydroxyglutarate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

malate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the malate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

nadh dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the nadh dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

butyryl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the butyryl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

1-pyrroline dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 1-pyrroline dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

aspartate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the aspartate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

succinate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the succinate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

15-hydroxyprostaglandin dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the 15-hydroxyprostaglandin dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

glucose-6-phosphate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the glucose-6-phosphate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

pyruvate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the pyruvate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

steroid dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the steroid dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity molecular function from the curated GO Molecular Function Annotations dataset.

l-aminoadipate-semialdehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the l-aminoadipate-semialdehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

4-trimethylammoniobutyraldehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 4-trimethylammoniobutyraldehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

saccharopine dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the saccharopine dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

glycerol-3-phosphate dehydrogenase [nad+] activity Gene Set

From GO Molecular Function Annotations

genes performing the glycerol-3-phosphate dehydrogenase [nad+] activity molecular function from the curated GO Molecular Function Annotations dataset.

imp dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the imp dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

malate dehydrogenase (decarboxylating) (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the malate dehydrogenase (decarboxylating) (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

androsterone dehydrogenase (b-specific) activity Gene Set

From GO Molecular Function Annotations

genes performing the androsterone dehydrogenase (b-specific) activity molecular function from the curated GO Molecular Function Annotations dataset.

benzaldehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the benzaldehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

oxoglutarate dehydrogenase (succinyl-transferring) activity Gene Set

From GO Molecular Function Annotations

genes performing the oxoglutarate dehydrogenase (succinyl-transferring) activity molecular function from the curated GO Molecular Function Annotations dataset.

succinate-semialdehyde dehydrogenase [nad(p)+] activity Gene Set

From GO Molecular Function Annotations

genes performing the succinate-semialdehyde dehydrogenase [nad(p)+] activity molecular function from the curated GO Molecular Function Annotations dataset.

estradiol 17-beta-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the estradiol 17-beta-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

malate dehydrogenase (decarboxylating) (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the malate dehydrogenase (decarboxylating) (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

isovaleryl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the isovaleryl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

pyruvate dehydrogenase (acetyl-transferring) kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the pyruvate dehydrogenase (acetyl-transferring) kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

aldehyde dehydrogenase [nad(p)+] activity Gene Set

From GO Molecular Function Annotations

genes performing the aldehyde dehydrogenase [nad(p)+] activity molecular function from the curated GO Molecular Function Annotations dataset.

saccharopine dehydrogenase (nadp+, l-lysine-forming) activity Gene Set

From GO Molecular Function Annotations

genes performing the saccharopine dehydrogenase (nadp+, l-lysine-forming) activity molecular function from the curated GO Molecular Function Annotations dataset.

glycerate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the glycerate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

very-long-chain-acyl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the very-long-chain-acyl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

choline dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the choline dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-oxo-5-alpha-steroid 4-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-oxo-5-alpha-steroid 4-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

steroid dehydrogenase activity, acting on the ch-ch group of donors Gene Set

From GO Molecular Function Annotations

genes performing the steroid dehydrogenase activity, acting on the ch-ch group of donors molecular function from the curated GO Molecular Function Annotations dataset.

testosterone dehydrogenase [nad(p)] activity Gene Set

From GO Molecular Function Annotations

genes performing the testosterone dehydrogenase [nad(p)] activity molecular function from the curated GO Molecular Function Annotations dataset.

methylenetetrahydrofolate dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the methylenetetrahydrofolate dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

(r)-2-hydroxyglutarate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the (r)-2-hydroxyglutarate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

isocitrate dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the isocitrate dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

alpha-ketoacid dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the alpha-ketoacid dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

benzaldehyde dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the benzaldehyde dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

nadp-retinol dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the nadp-retinol dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

dihydrolipoyl dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the dihydrolipoyl dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-chloroallyl aldehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-chloroallyl aldehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

long-chain-3-hydroxyacyl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the long-chain-3-hydroxyacyl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

aminobutyraldehyde dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the aminobutyraldehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

malate dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the malate dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

indanol dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the indanol dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

d-lactate dehydrogenase (cytochrome) activity Gene Set

From GO Molecular Function Annotations

genes performing the d-lactate dehydrogenase (cytochrome) activity molecular function from the curated GO Molecular Function Annotations dataset.

dihydropyrimidine dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the dihydropyrimidine dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

testosterone dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the testosterone dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

nadh dehydrogenase (ubiquinone) activity Gene Set

From GO Molecular Function Annotations

genes performing the nadh dehydrogenase (ubiquinone) activity molecular function from the curated GO Molecular Function Annotations dataset.

glutamate dehydrogenase [nad(p)+] activity Gene Set

From GO Molecular Function Annotations

genes performing the glutamate dehydrogenase [nad(p)+] activity molecular function from the curated GO Molecular Function Annotations dataset.

alcohol dehydrogenase (nad) activity Gene Set

From GO Molecular Function Annotations

genes performing the alcohol dehydrogenase (nad) activity molecular function from the curated GO Molecular Function Annotations dataset.

retinol dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the retinol dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

long-chain-acyl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the long-chain-acyl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

d-xylose 1-dehydrogenase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the d-xylose 1-dehydrogenase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

isocitrate dehydrogenase (nad+) activity Gene Set

From GO Molecular Function Annotations

genes performing the isocitrate dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations dataset.

dimethylglycine dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the dimethylglycine dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-hydroxyisobutyrate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-hydroxyisobutyrate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

dihydrotestosterone 17-beta-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the dihydrotestosterone 17-beta-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-hydroxy-2-methylbutyryl-coa dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-hydroxy-2-methylbutyryl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

formyltetrahydrofolate dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the formyltetrahydrofolate dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

nadph dehydrogenase (quinone) activity Gene Set

From GO Molecular Function Annotations

genes performing the nadph dehydrogenase (quinone) activity molecular function from the curated GO Molecular Function Annotations dataset.

cholate 7-alpha-dehydrogenase activity Gene Set

From GO Molecular Function Annotations

genes performing the cholate 7-alpha-dehydrogenase activity molecular function from the curated GO Molecular Function Annotations dataset.

reduced dihydropyrimidine dehydrogenase activity Gene Set

From HPO Gene-Disease Associations

genes associated with the reduced dihydropyrimidine dehydrogenase activity phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

decreased activity of the pyruvate dehydrogenase (pdh) complex Gene Set

From HPO Gene-Disease Associations

genes associated with the decreased activity of the pyruvate dehydrogenase (pdh) complex phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

reduced xanthine dehydrogenase activity Gene Set

From HPO Gene-Disease Associations

genes associated with the reduced xanthine dehydrogenase activity phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

FMN-dependent alpha-hydroxy acid dehydrogenase, active site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the FMN-dependent alpha-hydroxy acid dehydrogenase, active site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydroorotate dehydrogenase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydroorotate dehydrogenase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose-6-phosphate dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose-6-phosphate dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydroorotate dehydrogenase, class 1/ 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydroorotate dehydrogenase, class 1/ 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde oxidase/xanthine dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde oxidase/xanthine dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-oxo-5-alpha-steroid 4-dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-oxo-5-alpha-steroid 4-dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase, iron-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase, iron-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria protein domain from the InterPro Predicted Protein Domain Annotations dataset.

CO dehydrogenase flavoprotein, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CO dehydrogenase flavoprotein, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

UDP-glucose/GDP-mannose dehydrogenase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the UDP-glucose/GDP-mannose dehydrogenase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose-6-phosphate dehydrogenase, NAD-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose-6-phosphate dehydrogenase, NAD-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase, flavoprotein subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase, flavoprotein subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase family, zinc-type, class-V subfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase family, zinc-type, class-V subfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Malate dehydrogenase, NAD-dependent, cytosolic Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Malate dehydrogenase, NAD-dependent, cytosolic protein domain from the InterPro Predicted Protein Domain Annotations dataset.

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

2-oxoacid dehydrogenase acyltransferase, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 2-oxoacid dehydrogenase acyltransferase, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dehydrogenase, multihelical Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dehydrogenase, multihelical protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Quinonprotein alcohol dehydrogenase-like superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Quinonprotein alcohol dehydrogenase-like superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydroorotate dehydrogenase domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydroorotate dehydrogenase domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase subunit 5, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase subunit 5, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dehydrogenase, E1 component Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dehydrogenase, E1 component protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/Fumarate reductase, transmembrane subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/Fumarate reductase, transmembrane subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Acyl-CoA oxidase/dehydrogenase, central domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Acyl-CoA oxidase/dehydrogenase, central domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Quinonprotein alcohol dehydrogenase-like domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Quinonprotein alcohol dehydrogenase-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

L-aspartate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the L-aspartate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase, cytochrome b556 subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase, cytochrome b556 subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Isopropylmalate dehydrogenase-like domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Isopropylmalate dehydrogenase-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glyceraldehyde/Erythrose phosphate dehydrogenase family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glyceraldehyde/Erythrose phosphate dehydrogenase family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

UDP-glucose/GDP-mannose dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the UDP-glucose/GDP-mannose dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose/Sorbosone dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose/Sorbosone dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-hydroxyisobutyrate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-hydroxyisobutyrate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydrolipoamide dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydrolipoamide dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-hydroxyisobutyrate dehydrogenase-related, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-hydroxyisobutyrate dehydrogenase-related, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

UDP-glucose/GDP-mannose dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the UDP-glucose/GDP-mannose dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Saccharopine dehydrogenase / Homospermidine synthase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Saccharopine dehydrogenase / Homospermidine synthase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

10-formyltetrahydrofolate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 10-formyltetrahydrofolate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dehydrogenase/reductase SDR member 4-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dehydrogenase/reductase SDR member 4-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Molybdopterin dehydrogenase, FAD-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Molybdopterin dehydrogenase, FAD-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glutamate/phenylalanine/leucine/valine dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glutamate/phenylalanine/leucine/valine dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Pyruvate dehydrogenase E1 component subunit beta Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pyruvate dehydrogenase E1 component subunit beta protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde dehydrogenase domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde dehydrogenase domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Methylmalonate-semialdehyde dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methylmalonate-semialdehyde dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADP-dependent 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADP-dependent 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose-6-phosphate dehydrogenase, active site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose-6-phosphate dehydrogenase, active site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-hydroxyacyl-CoA dehydrogenase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-hydroxyacyl-CoA dehydrogenase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

6-phosphogluconate dehydrogenase, NADP-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 6-phosphogluconate dehydrogenase, NADP-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aspartate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aspartate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/fumarate reductase, flavoprotein subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Lactate/malate dehydrogenase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lactate/malate dehydrogenase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

UDP-glucose/GDP-mannose dehydrogenase, dimerisation Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the UDP-glucose/GDP-mannose dehydrogenase, dimerisation protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde dehydrogenase, glutamic acid active site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde dehydrogenase, glutamic acid active site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde dehydrogenase N-terminal domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde dehydrogenase N-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydroprymidine dehydrogenase domain II Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydroprymidine dehydrogenase domain II protein domain from the InterPro Predicted Protein Domain Annotations dataset.

CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

IMP dehydrogenase/GMP reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the IMP dehydrogenase/GMP reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Fibritin/6-phosphogluconate dehydrogenase, C-terminal extension Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fibritin/6-phosphogluconate dehydrogenase, C-terminal extension protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase family, zinc-type, class-IV subfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase family, zinc-type, class-IV subfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate semialdehyde dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate semialdehyde dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dehydrogenase/reductase SDR member 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dehydrogenase/reductase SDR member 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde dehydrogenase NAD(P)-dependent Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde dehydrogenase NAD(P)-dependent protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Malate dehydrogenase, type 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Malate dehydrogenase, type 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Malate dehydrogenase, type 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Malate dehydrogenase, type 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Acyl-CoA dehydrogenase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Acyl-CoA dehydrogenase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inosine-5'-monophosphate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inosine-5'-monophosphate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

D-3-phosphoglycerate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-3-phosphoglycerate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase superfamily, zinc-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase superfamily, zinc-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/fumarate reductase iron-sulphur protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/fumarate reductase iron-sulphur protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Flavinator of succinate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Flavinator of succinate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Fumarate reductase/succinate dehydrogenase, FAD-binding site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fumarate reductase/succinate dehydrogenase, FAD-binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Xanthine dehydrogenase, small subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Xanthine dehydrogenase, small subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-hydroxyacyl-CoA dehydrogenase, NAD binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-hydroxyacyl-CoA dehydrogenase, NAD binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

6-phosphogluconate dehydrogenase, C-terminal-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 6-phosphogluconate dehydrogenase, C-terminal-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-hydroxyacyl-CoA dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-hydroxyacyl-CoA dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase GroES-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase GroES-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

6-phosphogluconate dehydrogenase, decarboxylating Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 6-phosphogluconate dehydrogenase, decarboxylating protein domain from the InterPro Predicted Protein Domain Annotations dataset.

L-lactate dehydrogenase, active site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the L-lactate dehydrogenase, active site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glyceraldehyde-3-phosphate dehydrogenase, type I Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glyceraldehyde-3-phosphate dehydrogenase, type I protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Acyl-CoA dehydrogenase/oxidase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Acyl-CoA dehydrogenase/oxidase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase subunit 2, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase subunit 2, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase 1, beta subcomplex, subunit 6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase 1, beta subcomplex, subunit 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose/ribitol dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose/ribitol dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Proline dehydrogenase domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Proline dehydrogenase domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

FAD-dependent glycerol-3-phosphate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the FAD-dependent glycerol-3-phosphate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

L-lactate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the L-lactate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

IMP dehydrogenase / GMP reductase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the IMP dehydrogenase / GMP reductase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Acyl-CoA dehydrogenase/oxidase C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Acyl-CoA dehydrogenase/oxidase C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Short-chain dehydrogenase/reductase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Short-chain dehydrogenase/reductase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aspartate/homoserine dehydrogenase, NAD-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aspartate/homoserine dehydrogenase, NAD-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alpha-hydroxy acid dehydrogenase, FMN-dependent Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alpha-hydroxy acid dehydrogenase, FMN-dependent protein domain from the InterPro Predicted Protein Domain Annotations dataset.

2-oxo acid dehydrogenase, lipoyl-binding site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 2-oxo acid dehydrogenase, lipoyl-binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

6-phosphogluconate dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 6-phosphogluconate dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

3-hydroxyacyl-CoA dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 3-hydroxyacyl-CoA dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Lactate/malate dehydrogenase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lactate/malate dehydrogenase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

L-lactate/malate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the L-lactate/malate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Quinoprotein amine dehydrogenase, beta chain-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Quinoprotein amine dehydrogenase, beta chain-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase, zinc-type, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase, zinc-type, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Isocitrate/isopropylmalate dehydrogenase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Isocitrate/isopropylmalate dehydrogenase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glyceraldehyde 3-phosphate dehydrogenase, active site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glyceraldehyde 3-phosphate dehydrogenase, active site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose-6-phosphate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose-6-phosphate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Short-chain dehydrogenase/reductase SDR Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Short-chain dehydrogenase/reductase SDR protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase, subunit C Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase, subunit C protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase assembly factor 2, mitochondrial Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase assembly factor 2, mitochondrial protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Soluble quinoprotein glucose/sorbosone dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Soluble quinoprotein glucose/sorbosone dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldehyde dehydrogenase, cysteine active site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldehyde dehydrogenase, cysteine active site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Isocitrate dehydrogenase NADP-dependent Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Isocitrate dehydrogenase NADP-dependent protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Delta-1-pyrroline-5-carboxylate dehydrogenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Delta-1-pyrroline-5-carboxylate dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

2-oxoglutarate dehydrogenase E1 component Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 2-oxoglutarate dehydrogenase E1 component protein domain from the InterPro Predicted Prote