UBP22_HUMAN Protein

Name Ubiquitin carboxyl-terminal hydrolase 22
Description Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
UniProt ID Q9UPT9
Gene USP22