TIGIT_HUMAN Protein

Name T-cell immunoreceptor with Ig and ITIM domains
Description Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
UniProt ID Q495A1
Gene TIGIT