PEG3_HUMAN Protein

Name Paternally-expressed gene 3 protein
Description Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.
UniProt ID Q9GZU2
Gene PEG3