MGMT_HUMAN Protein

Name Methylated-DNA--protein-cysteine methyltransferase
Description Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
UniProt ID P16455
Gene MGMT