ARG28_HUMAN Protein

Name Rho guanine nucleotide exchange factor 28
Description Functions as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Functions in axonal branching, synapse formation and dendritic morphogenesis. Functions also in focal adhesion formation, cell motility and B-lymphocytes activation. May regulate NEFL expression and aggregation and play a role in apoptosis (By similarity).
UniProt ID Q8N1W1
Gene ARHGEF28