zoxazolamine-6290 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the zoxazolamine-6290 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
AGO4 argonaute RISC catalytic component 4
AIM1L absent in melanoma 1-like
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APOM apolipoprotein M
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARSB arylsulfatase B
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C9ORF156 chromosome 9 open reading frame 156
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDHR5 cadherin-related family member 5
CEP295 centrosomal protein 295kDa
CLDN11 claudin 11
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DMTN dematin actin binding protein
DMWD dystrophia myotonica, WD repeat containing
DRD2 dopamine receptor D2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EML3 echinoderm microtubule associated protein like 3
EPHB1 EPH receptor B1
ERF Ets2 repressor factor
ERP44 endoplasmic reticulum protein 44
EXOSC2 exosome component 2
FLJ11292
GCGR glucagon receptor
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GGT1 gamma-glutamyltransferase 1
GPR17 G protein-coupled receptor 17
GRIP2 glutamate receptor interacting protein 2
GRM1 glutamate receptor, metabotropic 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIST1H1E histone cluster 1, H1e
HOXB5 homeobox B5
HSF2 heat shock transcription factor 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1107 KIAA1107
LAT2 linker for activation of T cells family, member 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEF1 lymphoid enhancer-binding factor 1
LMF1 lipase maturation factor 1
LMNA lamin A/C
LTC4S leukotriene C4 synthase
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED28 mediator complex subunit 28
MSLN mesothelin
MSX2 msh homeobox 2
MTRF1L mitochondrial translational release factor 1-like
MVB12B multivesicular body subunit 12B
NCAPH2 non-SMC condensin II complex, subunit H2
NPEPL1 aminopeptidase-like 1
PADI1 peptidyl arginine deiminase, type I
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLXNC1 plexin C1
PP14571 uncharacterized LOC100130449
PRSS16 protease, serine, 16 (thymus)
RAB33A RAB33A, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RANGAP1 Ran GTPase activating protein 1
RARG retinoic acid receptor, gamma
RECQL5 RecQ protein-like 5
RPH3A rabphilin 3A
RPP25 ribonuclease P/MRP 25kDa subunit
RRAGD Ras-related GTP binding D
RRBP1 ribosome binding protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SOS2 son of sevenless homolog 2 (Drosophila)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SS18 synovial sarcoma translocation, chromosome 18
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STON1 stonin 1
SUN2 Sad1 and UNC84 domain containing 2
TBXA2R thromboxane A2 receptor
TFDP3 transcription factor Dp family, member 3
TLR4 toll-like receptor 4
TMEM206 transmembrane protein 206
TNK1 tyrosine kinase, non-receptor, 1
TSC22D2 TSC22 domain family, member 2
USP19 ubiquitin specific peptidase 19
VEZT vezatin, adherens junctions transmembrane protein
WAS Wiskott-Aldrich syndrome
WTAP Wilms tumor 1 associated protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF556 zinc finger protein 556
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ALDOC aldolase C, fructose-bisphosphate
ALPK1 alpha-kinase 1
CDC45 cell division cycle 45
CENPC centromere protein C
CLCN2 chloride channel, voltage-sensitive 2
CTSK cathepsin K
DCAF13 DDB1 and CUL4 associated factor 13
DCAF4 DDB1 and CUL4 associated factor 4
DCLRE1A DNA cross-link repair 1A
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EAF2 ELL associated factor 2
EGF epidermal growth factor
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPPK1 epiplakin 1
ETV4 ets variant 4
FER fer (fps/fes related) tyrosine kinase
FKBPL FK506 binding protein like
FZD3 frizzled class receptor 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPALPP1 GPALPP motifs containing 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUSBP3 glucuronidase, beta pseudogene 3
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HIST1H3G histone cluster 1, H3g
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HYAL3 hyaluronoglucosaminidase 3
IL4R interleukin 4 receptor
IL7R interleukin 7 receptor
IRF1 interferon regulatory factor 1
IRF6 interferon regulatory factor 6
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MANSC1 MANSC domain containing 1
MAPK12 mitogen-activated protein kinase 12
MLF2 myeloid leukemia factor 2
MOGS mannosyl-oligosaccharide glucosidase
MYO19 myosin XIX
NDE1 nudE neurodevelopment protein 1
NMRK1 nicotinamide riboside kinase 1
NPM3 nucleophosmin/nucleoplasmin 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PACS1 phosphofurin acidic cluster sorting protein 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PAQR4 progestin and adipoQ receptor family member IV
PARPBP PARP1 binding protein
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLEKHO2 pleckstrin homology domain containing, family O member 2
POR P450 (cytochrome) oxidoreductase
PPT2 palmitoyl-protein thioesterase 2
PRAME preferentially expressed antigen in melanoma
PRPF38B pre-mRNA processing factor 38B
PRPH peripherin
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RASA2 RAS p21 protein activator 2
RNF219 ring finger protein 219
RNF31 ring finger protein 31
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCAI suppressor of cancer cell invasion
SCAMP4 secretory carrier membrane protein 4
SCN1B sodium channel, voltage gated, type I beta subunit
SETD6 SET domain containing 6
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SND1-IT1 SND1 intronic transcript 1
SNX24 sorting nexin 24
SOAT1 sterol O-acyltransferase 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TBP TATA box binding protein
TLN1 talin 1
TOR4A torsin family 4, member A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TUBA3C tubulin, alpha 3c
UBXN6 UBX domain protein 6
USP27X ubiquitin specific peptidase 27, X-linked
VSIG10 V-set and immunoglobulin domain containing 10
WDR19 WD repeat domain 19
WDR5B WD repeat domain 5B
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP36 ZFP36 ring finger protein
ZNF204P zinc finger protein 204, pseudogene
ZNF324 zinc finger protein 324
ZNF426 zinc finger protein 426
ZNF571 zinc finger protein 571