weight loss Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Reduction inexisting body weight. (Human Phenotype Ontology, HP_0001824)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001824
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Genes

108 genes associated with the weight loss phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AK2 adenylate kinase 2
ATM ATM serine/threonine kinase
AVP arginine vasopressin
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BIRC3 baculoviral IAP repeat containing 3
BMPR1A bone morphogenetic protein receptor, type IA
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTK Bruton agammaglobulinemia tyrosine kinase
C4A complement component 4A (Rodgers blood group)
CCND1 cyclin D1
CDKL5 cyclin-dependent kinase-like 5
COL7A1 collagen, type VII, alpha 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DCTN1 dynactin 1
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
ECE1 endothelin converting enzyme 1
EDN3 endothelin 3
EDNRB endothelin receptor type B
EPCAM epithelial cell adhesion molecule
ERCC4 excision repair cross-complementation group 4
EWSR1 EWS RNA-binding protein 1
F5 coagulation factor V (proaccelerin, labile factor)
FANCA Fanconi anemia, complementation group A
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FANCF Fanconi anemia, complementation group F
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FANCL Fanconi anemia, complementation group L
FANCM Fanconi anemia, complementation group M
FOXG1 forkhead box G1
FOXP1 forkhead box P1
GALT galactose-1-phosphate uridylyltransferase
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GBA glucosidase, beta, acid
GDNF glial cell derived neurotrophic factor
GJB3 gap junction protein, beta 3, 31kDa
GJB4 gap junction protein, beta 4, 30.3kDa
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMBS hydroxymethylbilane synthase
IL10 interleukin 10
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
JAK2 Janus kinase 2
JPH3 junctophilin 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT1 keratin 1, type II
KRT10 keratin 10, type I
L1CAM L1 cell adhesion molecule
LIPA lipase A, lysosomal acid, cholesterol esterase
LMNA lamin A/C
LPIN2 lipin 2
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MALT1 MALT1 paracaspase
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MLX MLX, MAX dimerization protein
MPL MPL proto-oncogene, thrombopoietin receptor
MSH2 mutS homolog 2
MSH6 mutS homolog 6
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NRTN neurturin
NTNG1 netrin G1
PALB2 partner and localizer of BRCA2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLG polymerase (DNA directed), gamma
POU6F2 POU class 6 homeobox 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRNP prion protein
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAD51C RAD51 paralog C
RET ret proto-oncogene
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLX4 SLX4 structure-specific endonuclease subunit
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAT4 signal transducer and activator of transcription 4
TET2 tet methylcytosine dioxygenase 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THPO thrombopoietin
TLR4 toll-like receptor 4
TYMP thymidine phosphorylase
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WT1 Wilms tumor 1
ZMPSTE24 zinc metallopeptidase STE24