vorinostat-2680 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the vorinostat-2680 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AREG amphiregulin
ARG2 arginase 2
ARHGAP29 Rho GTPase activating protein 29
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC9 armadillo repeat containing 9
ASMTL acetylserotonin O-methyltransferase-like
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CD59 CD59 molecule, complement regulatory protein
CEP70 centrosomal protein 70kDa
CPM carboxypeptidase M
CREB3 cAMP responsive element binding protein 3
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRNP2 cysteine-serine-rich nuclear protein 2
CSRP2 cysteine and glycine-rich protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CXADR coxsackie virus and adenovirus receptor
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAAM1 dishevelled associated activator of morphogenesis 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DSP desmoplakin
ECI2 enoyl-CoA delta isomerase 2
EFNA4 ephrin-A4
EFNB2 ephrin-B2
ELOVL4 ELOVL fatty acid elongase 4
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
F11R F11 receptor
FAM49A family with sequence similarity 49, member A
FAM89B family with sequence similarity 89, member B
FUCA1 fucosidase, alpha-L- 1, tissue
GCH1 GTP cyclohydrolase 1
GK3P glycerol kinase 3 pseudogene
GRK5 G protein-coupled receptor kinase 5
GSDMB gasdermin B
H1F0 H1 histone family, member 0
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IFI6 interferon, alpha-inducible protein 6
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA0226L KIAA0226-like
KIAA0513 KIAA0513
KIF3A kinesin family member 3A
KIF5C kinesin family member 5C
LPIN1 lipin 1
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MARCKS myristoylated alanine-rich protein kinase C substrate
MCOLN1 mucolipin 1
MPZL1 myelin protein zero-like 1
MTCL1 microtubule crosslinking factor 1
MTSS1 metastasis suppressor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NBEA neurobeachin
NCAM1 neural cell adhesion molecule 1
NEU1 sialidase 1 (lysosomal sialidase)
OAZ2 ornithine decarboxylase antizyme 2
PALLD palladin, cytoskeletal associated protein
PCDH9 protocadherin 9
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PFN2 profilin 2
PGBD5 piggyBac transposable element derived 5
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLS1 plastin 1
POLB polymerase (DNA directed), beta
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RFPL3S RFPL3 antisense
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC25A44 solute carrier family 25, member 44
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNN stannin
SRR serine racemase
STXBP1 syntaxin binding protein 1
TBC1D16 TBC1 domain family, member 16
TECPR2 tectonin beta-propeller repeat containing 2
TESK2 testis-specific kinase 2
TRAFD1 TRAF-type zinc finger domain containing 1
TSPAN13 tetraspanin 13
TSPAN4 tetraspanin 4
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TULP3 tubby like protein 3
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZC2HC1A zinc finger, C2HC-type containing 1A
ZER1 zyg-11 related, cell cycle regulator
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADNP activity-dependent neuroprotector homeobox
APOBR apolipoprotein B receptor
ATP8B4 ATPase, class I, type 8B, member 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C11ORF21 chromosome 11 open reading frame 21
C9ORF91 chromosome 9 open reading frame 91
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CLEC5A C-type lectin domain family 5, member A
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CTCF CCCTC-binding factor (zinc finger protein)
CXCL8 chemokine (C-X-C motif) ligand 8
CXORF21 chromosome X open reading frame 21
CYTIP cytohesin 1 interacting protein
DEAF1 DEAF1 transcription factor
DENND2D DENN/MADD domain containing 2D
DOK2 docking protein 2, 56kDa
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FADD Fas (TNFRSF6)-associated via death domain
FAM57A family with sequence similarity 57, member A
FAR2 fatty acyl CoA reductase 2
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FES FES proto-oncogene, tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
GFI1 growth factor independent 1 transcription repressor
GPR18 G protein-coupled receptor 18
GPR183 G protein-coupled receptor 183
GRAMD1B GRAM domain containing 1B
GSE1 Gse1 coiled-coil protein
HIST1H2AJ histone cluster 1, H2aj
HLX H2.0-like homeobox
HMHA1 histocompatibility (minor) HA-1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL4R interleukin 4 receptor
JADE1 jade family PHD finger 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KEAP1 kelch-like ECH-associated protein 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LMNB1 lamin B1
LTB lymphotoxin beta (TNF superfamily, member 3)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MCM9 minichromosome maintenance complex component 9
MEIS2 Meis homeobox 2
MEPCE methylphosphate capping enzyme
MOCOS molybdenum cofactor sulfurase
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFE2 nuclear factor, erythroid 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NMI N-myc (and STAT) interactor
NOD1 nucleotide-binding oligomerization domain containing 1
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PEF1 penta-EF-hand domain containing 1
PLAU plasminogen activator, urokinase
PMF1 polyamine-modulated factor 1
PON2 paraoxonase 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRDM13 PR domain containing 13
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RBM23 RNA binding motif protein 23
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGS19 regulator of G-protein signaling 19
RHOBTB1 Rho-related BTB domain containing 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SNHG3 small nucleolar RNA host gene 3
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TARP TCR gamma alternate reading frame protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMED1 transmembrane emp24 protein transport domain containing 1
TNF tumor necrosis factor
TRAC T cell receptor alpha constant
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UCK2 uridine-cytidine kinase 2
WT1 Wilms tumor 1
XAF1 XIAP associated factor 1
ZC3H4 zinc finger CCCH-type containing 4
ZEB2 zinc finger E-box binding homeobox 2
ZHX2 zinc fingers and homeoboxes 2
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2