venous insufficiency Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A vein disease that is characterized by impaired flow of blood through the veins. (Human Disease Ontology, DOID_10128)
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Genes

113 genes co-occuring with the disease venous insufficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PARVA parvin, alpha 1.432
SZRD1 SUZ RNA binding domain containing 1 1.27868
GLTP glycolipid transfer protein 1.24168
HSF5 heat shock transcription factor family member 5 1.09377
FOXC2 forkhead box C2 1.04335
PLAT plasminogen activator, tissue 1.02945
F5 coagulation factor V (proaccelerin, labile factor) 0.964986
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.902799
ANKLE1 ankyrin repeat and LEM domain containing 1 0.848716
VILL villin-like 0.817155
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.781888
C4A complement component 4A (Rodgers blood group) 0.748424
ICAM1 intercellular adhesion molecule 1 0.739894
MMP2 matrix metallopeptidase 2 0.735433
PLG plasminogen 0.731786
EVL Enah/Vasp-like 0.71925
GZMM granzyme M (lymphocyte met-ase 1) 0.716828
VCAM1 vascular cell adhesion molecule 1 0.716425
EZR ezrin 0.709169
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.672324
WAC WW domain containing adaptor with coiled-coil 0.669538
ITM2B integral membrane protein 2B 0.633169
IFT122 intraflagellar transport 122 0.631991
SYCP3 synaptonemal complex protein 3 0.630027
F3 coagulation factor III (thromboplastin, tissue factor) 0.605372
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.604591
NDP Norrie disease (pseudoglioma) 0.59874
CDO1 cysteine dioxygenase type 1 0.58939
MVD mevalonate (diphospho) decarboxylase 0.583163
AMELY amelogenin, Y-linked 0.577716
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.557897
AMELX amelogenin, X-linked 0.545481
TGFB1 transforming growth factor, beta 1 0.532314
SPAG7 sperm associated antigen 7 0.521117
PRKCD protein kinase C, delta 0.519961
PTS 6-pyruvoyltetrahydropterin synthase 0.519575
F2 coagulation factor II (thrombin) 0.515725
PROS1 protein S (alpha) 0.513802
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.510344
KNG1 kininogen 1 0.503058
ALYREF Aly/REF export factor 0.487788
CDT1 chromatin licensing and DNA replication factor 1 0.482464
SELE selectin E 0.480566
BSN bassoon presynaptic cytomatrix protein 0.470711
VGF VGF nerve growth factor inducible 0.469576
EDN1 endothelin 1 0.466172
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.460883
PTPRD protein tyrosine phosphatase, receptor type, D 0.4443
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.440538
DNM1 dynamin 1 0.43941
PNMA1 paraneoplastic Ma antigen 1 0.439034
FAM155B family with sequence similarity 155, member B 0.427765
HRK harakiri, BCL2 interacting protein 0.41465
MMP9 matrix metallopeptidase 9 0.411283
FHL1 four and a half LIM domains 1 0.409787
MPO myeloperoxidase 0.404184
MMP1 matrix metallopeptidase 1 0.393374
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.391885
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.379997
CRP C-reactive protein, pentraxin-related 0.374809
FOXP2 forkhead box P2 0.371107
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.361502
TTR transthyretin 0.346042
FTL ferritin, light polypeptide 0.343473
FTH1 ferritin, heavy polypeptide 1 0.343473
CA6 carbonic anhydrase VI 0.342739
GRHL1 grainyhead-like 1 (Drosophila) 0.340906
HYLS1 hydrolethalus syndrome 1 0.324823
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.324458
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.319726
AMD1 adenosylmethionine decarboxylase 1 0.310652
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.301615
VWF von Willebrand factor 0.298731
FN1 fibronectin 1 0.297651
KIAA0101 KIAA0101 0.292616
CAMP cathelicidin antimicrobial peptide 0.279367
CD68 CD68 molecule 0.27794
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.275089
PLAU plasminogen activator, urokinase 0.271886
ALB albumin 0.253831
SELL selectin L 0.251366
CRLF1 cytokine receptor-like factor 1 0.242245
IL6 interleukin 6 0.241895
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.219398
EFS embryonal Fyn-associated substrate 0.215992
CLDN3 claudin 3 0.215314
IL1A interleukin 1, alpha 0.213959
FOXC1 forkhead box C1 0.213283
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.200656
MMP25 matrix metallopeptidase 25 0.196459
VIL1 villin 1 0.1936
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.189551
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.188022
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.188022
IL1B interleukin 1, beta 0.187719
LOXL1 lysyl oxidase-like 1 0.187415
CYLD cylindromatosis (turban tumor syndrome) 0.178403
FGF2 fibroblast growth factor 2 (basic) 0.177851
FBN2 fibrillin 2 0.177029
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.175947
CLDN5 claudin 5 0.170054
CCNI cyclin I 0.168617
SOD2 superoxide dismutase 2, mitochondrial 0.166544
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.164571
GLB1 galactosidase, beta 1 0.163938
CXCL8 chemokine (C-X-C motif) ligand 8 0.163317
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.161139
C1S complement component 1, s subcomponent 0.159124
EPHA4 EPH receptor A4 0.157929
PF4 platelet factor 4 0.157765
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.144866
TBX1 T-box 1 0.144571
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.144452