valve Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

125 genes co-occuring with the biological term valve in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX5 arachidonate 5-lipoxygenase
APLN apelin
APLNR apelin receptor
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AXIN1 axin 1
BGN biglycan
BMP4 bone morphogenetic protein 4
CD44 CD44 molecule (Indian blood group)
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COL3A1 collagen, type III, alpha 1
CRP C-reactive protein, pentraxin-related
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLX5 distal-less homeobox 5
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
ELN elastin
ENG endoglin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
F2 coagulation factor II (thrombin)
FBLN1 fibulin 1
FBN1 fibrillin 1
FGF2 fibroblast growth factor 2 (basic)
FLNA filamin A, alpha
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FOXC2 forkhead box C2
GATA5 GATA binding protein 5
GGCX gamma-glutamyl carboxylase
GGT1 gamma-glutamyltransferase 1
GLA galactosidase, alpha
HLA-B major histocompatibility complex, class I, B
HSPB1 heat shock 27kDa protein 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1R1 interleukin 1 receptor, type I
IL1RL1 interleukin 1 receptor-like 1
IL6 interleukin 6
ITGA9 integrin, alpha 9
JAG1 jagged 1
LCN2 lipocalin 2
LPA lipoprotein, Lp(a)
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MGP matrix Gla protein
MIR30B microRNA 30b
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC16 mucin 16, cell surface associated
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOG noggin
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPR2 natriuretic peptide receptor 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARP1 poly (ADP-ribose) polymerase 1
PDIA2 protein disulfide isomerase family A, member 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLTP phospholipid transfer protein
PRKCB protein kinase C, beta
PTH parathyroid hormone
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RB1 retinoblastoma 1
RCAN1 regulator of calcineurin 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCX scleraxis basic helix-loop-helix transcription factor
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SOD3 superoxide dismutase 3, extracellular
SOST sclerostin
SP7 Sp7 transcription factor
SPP1 secreted phosphoprotein 1
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TWIST1 twist family bHLH transcription factor 1
UGDH UDP-glucose 6-dehydrogenase
UTS2 urotensin 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VKORC1 vitamin K epoxide reductase complex, subunit 1
VWF von Willebrand factor