vacuolar membrane Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. (Gene Ontology, GO_0005774)
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Genes

228 proteins localized to the vacuolar membrane cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.663342
RPTOR regulatory associated protein of MTOR, complex 1 0.663342
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.663342
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.663342
SCARB1 scavenger receptor class B, member 1 0.663342
SCARB2 scavenger receptor class B, member 2 0.663342
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.663342
TMEM175 transmembrane protein 175 0.663342
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.663342
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.663342
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.663342
RAB14 RAB14, member RAS oncogene family 0.663342
GAA glucosidase, alpha; acid 0.663342
ATG9A autophagy related 9A 0.663342
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.663342
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.663342
MYO7A myosin VIIA 0.663342
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.663342
ATP11A ATPase, class VI, type 11A 0.663342
ATP11C ATPase, class VI, type 11C 0.663342
IFITM3 interferon induced transmembrane protein 3 0.663342
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.663342
CD1B CD1b molecule 0.663342
CD1D CD1d molecule 0.663342
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.663342
NEU1 sialidase 1 (lysosomal sialidase) 0.663342
STX7 syntaxin 7 0.663342
MARCH9 membrane-associated ring finger (C3HC4) 9 0.663342
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 0.663342
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.663342
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.663342
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.663342
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.663342
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.663342
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.663342
TPCN2 two pore segment channel 2 0.663342
MCOLN1 mucolipin 1 0.663342
CD63 CD63 molecule 0.663342
CD68 CD68 molecule 0.663342
LITAF lipopolysaccharide-induced TNF factor 0.663342
VAMP8 vesicle-associated membrane protein 8 0.663342
VAMP7 vesicle-associated membrane protein 7 0.663342
TMEM63A transmembrane protein 63A 0.663342
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.663342
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.663342
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 0.663342
GBA glucosidase, beta, acid 0.663342
RAB2A RAB2A, member RAS oncogene family 0.663342
SPNS1 spinster homolog 1 (Drosophila) 0.663342
ZFYVE26 zinc finger, FYVE domain containing 26 0.663342
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.663342
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.663342
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.663342
ARL8A ADP-ribosylation factor-like 8A 0.663342
ARL8B ADP-ribosylation factor-like 8B 0.663342
STARD3 StAR-related lipid transfer (START) domain containing 3 0.663342
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.663342
CP ceruloplasmin (ferroxidase) 0.663342
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.663342
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.663342
EGF epidermal growth factor 0.663342
HPSE heparanase 0.663342
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.663342
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.663342
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.663342
TMEM106B transmembrane protein 106B 0.663342
DPP4 dipeptidyl-peptidase 4 0.663342
STX17 syntaxin 17 0.663342
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 0.663342
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 0.663342
VASN vasorin 0.663342
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.663342
TMEM192 transmembrane protein 192 0.663342
MFSD8 major facilitator superfamily domain containing 8 0.663342
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 0.663342
TLR3 toll-like receptor 3 0.663342
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 0.663342
RILP Rab interacting lysosomal protein 0.663342
ATP13A2 ATPase type 13A2 0.663342
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.663342
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.663342
AHNAK AHNAK nucleoprotein 0.663342
NCSTN nicastrin 0.663342
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.663342
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.663342
RNF13 ring finger protein 13 0.663342
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.663342
C18ORF8 chromosome 18 open reading frame 8 0.663342
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.663342
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.663342
NSF N-ethylmaleimide-sensitive factor 0.663342
DEPDC5 DEP domain containing 5 0.663342
HLA-DRA major histocompatibility complex, class II, DR alpha 0.663342
ACPP acid phosphatase, prostate 0.663342
ACP2 acid phosphatase 2, lysosomal 0.663342
CYB561A3 cytochrome b561 family, member A3 0.663342
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.663342
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.663342
RRAGB Ras-related GTP binding B 0.663342
RRAGA Ras-related GTP binding A 0.663342
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.663342
CLCN5 chloride channel, voltage-sensitive 5 0.663342
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.663342
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.663342
STK11IP serine/threonine kinase 11 interacting protein 0.663342
ECE1 endothelin converting enzyme 1 0.663342
SPG11 spastic paraplegia 11 (autosomal recessive) 0.663342
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.663342
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.663342
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.663342
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.663342
CTNS cystinosin, lysosomal cystine transporter 0.663342
TMEM59 transmembrane protein 59 0.663342
STARD3NL STARD3 N-terminal like 0.663342
HLA-DMA major histocompatibility complex, class II, DM alpha 0.663342
LAMP1 lysosomal-associated membrane protein 1 0.663342
LAMP2 lysosomal-associated membrane protein 2 0.663342
LAMP3 lysosomal-associated membrane protein 3 0.663342
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.663342
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.663342
WDR11 WD repeat domain 11 0.663342
OCA2 oculocutaneous albinism II 0.663342
AP3M1 adaptor-related protein complex 3, mu 1 subunit 0.663342
PLD1 phospholipase D1, phosphatidylcholine-specific 0.663342
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.663342
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.663342
COL6A1 collagen, type VI, alpha 1 0.663342
GDAP2 ganglioside induced differentiation associated protein 2 0.663342
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.663342
LRP2 low density lipoprotein receptor-related protein 2 0.663342
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.663342
HLA-DOA major histocompatibility complex, class II, DO alpha 0.663342
TPCN1 two pore segment channel 1 0.663342
GPR143 G protein-coupled receptor 143 0.663342
TECPR1 tectonin beta-propeller repeat containing 1 0.663342
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 0.663342
WDR41 WD repeat domain 41 0.663342
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.663342
MFSD12 major facilitator superfamily domain containing 12 0.663342
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 0.663342
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.663342
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.663342
TMBIM1 transmembrane BAX inhibitor motif containing 1 0.663342
HLA-DOB major histocompatibility complex, class II, DO beta 0.663342
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.663342
TLDC1 TBC/LysM-associated domain containing 1 0.663342
FLOT1 flotillin 1 0.663342
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.663342
RAB5C RAB5C, member RAS oncogene family 0.663342
TMEM8A transmembrane protein 8A 0.663342
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.663342
CLN3 ceroid-lipofuscinosis, neuronal 3 0.663342
LNPEP leucyl/cystinyl aminopeptidase 0.663342
GABARAP GABA(A) receptor-associated protein 0.663342
NPC1 Niemann-Pick disease, type C1 0.663342
CLCN6 chloride channel, voltage-sensitive 6 0.663342
CLCN7 chloride channel, voltage-sensitive 7 0.663342
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.663342
SPHK2 sphingosine kinase 2 0.663342
SPPL2B signal peptide peptidase like 2B 0.663342
SPPL2A signal peptide peptidase like 2A 0.663342
SIDT2 SID1 transmembrane family, member 2 0.663342
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.663342
CLN5 ceroid-lipofuscinosis, neuronal 5 0.663342
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.663342
TMEM165 transmembrane protein 165 0.663342
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.663342
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 0.663342
PQLC2 PQ loop repeat containing 2 0.663342
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.663342
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.663342
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.663342
SLC35F6 solute carrier family 35, member F6 0.663342
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.663342
M6PR mannose-6-phosphate receptor (cation dependent) 0.663342
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.663342
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.663342
ANPEP alanyl (membrane) aminopeptidase 0.663342
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 0.663342
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.663342
MYO6 myosin VI 0.237908
OSTM1 osteopetrosis associated transmembrane protein 1 0.237908
DAGLB diacylglycerol lipase, beta 0.237908
HLA-DMB major histocompatibility complex, class II, DM beta 0.237908
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.237908
TLR9 toll-like receptor 9 0.237908
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.237908
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.237908
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.237908
VMP1 vacuole membrane protein 1 0.237908
TLR7 toll-like receptor 7 0.237908
ANXA6 annexin A6 0.237908
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.237908
RAB7A RAB7A, member RAS oncogene family 0.237908
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.237908
TMEM79 transmembrane protein 79 0.237908
ARRB1 arrestin, beta 1 0.237908
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.237908
AP1M1 adaptor-related protein complex 1, mu 1 subunit 0.237908
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.237908
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.237908
ANXA2 annexin A2 0.237908
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.237908
TRIM23 tripartite motif containing 23 0.237908
OSBPL1A oxysterol binding protein-like 1A 0.237908
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.237908
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.237908
AP1B1 adaptor-related protein complex 1, beta 1 subunit 0.237908
LMBRD1 LMBR1 domain containing 1 0.237908
PSAP prosaposin 0.237908
TLR8 toll-like receptor 8 0.237908
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.237908
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.098109
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.098109
PSEN2 presenilin 2 0.098109
PSEN1 presenilin 1 0.098109
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.03318
RPN2 ribophorin II 0.03318
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.03318
SBF2 SET binding factor 2 0.03318
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 0.03318
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 0.03318
STX8 syntaxin 8 0.03318
VAC14 Vac14 homolog (S. cerevisiae) 0.03318
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.03318
LAPTM5 lysosomal protein transmembrane 5 0.03318
MTMR2 myotubularin related protein 2 0.03318
HRG histidine-rich glycoprotein 0.006977