ubiquitin activating enzyme activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. (Gene Ontology, GO_0004839)
External Link http://amigo.geneontology.org/amigo/term/GO:0004839
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Genes

4 genes performing the ubiquitin activating enzyme activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ATG7 autophagy related 7
SAE1 SUMO1 activating enzyme subunit 1
UBA1 ubiquitin-like modifier activating enzyme 1
UBA7 ubiquitin-like modifier activating enzyme 7