tumorsuppressive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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135 genes co-occuring with the biological term tumorsuppressive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT2 v-akt murine thymoma viral oncogene homolog 2
AR androgen receptor
ARID1A AT rich interactive domain 1A (SWI-like)
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
CADM1 cell adhesion molecule 1
CASR calcium-sensing receptor
CCND1 cyclin D1
CCNE1 cyclin E1
CD14 CD14 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CMTM3 CKLF-like MARVEL transmembrane domain containing 3
CREB1 cAMP responsive element binding protein 1
CXCR4 chemokine (C-X-C motif) receptor 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
DUSP6 dual specificity phosphatase 6
EGF epidermal growth factor
EGLN1 egl-9 family hypoxia-inducible factor 1
EP400 E1A binding protein p400
EPHA3 EPH receptor A3
ESR2 estrogen receptor 2 (ER beta)
FBLN2 fibulin 2
FGFRL1 fibroblast growth factor receptor-like 1
FOXP3 forkhead box P3
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GOLM1 golgi membrane protein 1
GPC3 glypican 3
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HMGB1 high mobility group box 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPA9 heat shock 70kDa protein 9 (mortalin)
IER3 immediate early response 3
IGF2R insulin-like growth factor 2 receptor
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP7 insulin-like growth factor binding protein 7
ILK integrin-linked kinase
KDM5A lysine (K)-specific demethylase 5A
KLF4 Kruppel-like factor 4 (gut)
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LIN28B lin-28 homolog B (C. elegans)
LXN latexin
MAPK8 mitogen-activated protein kinase 8
MB myoglobin
MCRS1 microspherule protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR124-1 microRNA 124-1
MIR124-2 microRNA 124-2
MIR124-3 microRNA 124-3
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR126 microRNA 126
MIR1291 microRNA 1291
MIR133A1 microRNA 133a-1
MIR134 microRNA 134
MIR136 microRNA 136
MIR143 microRNA 143
MIR145 microRNA 145
MIR152 microRNA 152
MIR182 microRNA 182
MIR200B microRNA 200b
MIR200C microRNA 200c
MIR203A microRNA 203a
MIR205 microRNA 205
MIR21 microRNA 21
MIR210 microRNA 210
MIR218-1 microRNA 218-1
MIR22 microRNA 22
MIR27B microRNA 27b
MIR296 microRNA 296
MIR29A microRNA 29a
MIR29B1 microRNA 29b-1
MIR29C microRNA 29c
MIR31 microRNA 31
MIR34A microRNA 34a
MIR373 microRNA 373
MIR449A microRNA 449a
MIR504 microRNA 504
MIR520C microRNA 520c
MIR7-1 microRNA 7-1
MTDH metadherin
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
MZB1 marginal zone B and B1 cell-specific protein
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFE2L2 nuclear factor, erythroid 2-like 2
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NR3C2 nuclear receptor subfamily 3, group C, member 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCGF2 polycomb group ring finger 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLK1 polo-like kinase 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRDM5 PR domain containing 5
PRKCE protein kinase C, epsilon
PTEN phosphatase and tensin homolog
RBMX RNA binding motif protein, X-linked
RHOB ras homolog family member B
RTN4IP1 reticulon 4 interacting protein 1
S100A7 S100 calcium binding protein A7
SAMD9L sterile alpha motif domain containing 9-like
SCHLAP1 SWI/SNF complex antagonist associated with prostate cancer 1 (non-protein coding)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SFRP2 secreted frizzled-related protein 2
SIRT4 sirtuin 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SPRY2 sprouty homolog 2 (Drosophila)
SS18 synovial sarcoma translocation, chromosome 18
STAT5B signal transducer and activator of transcription 5B
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TP53 tumor protein p53
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
USP25 ubiquitin specific peptidase 25
XIST X inactive specific transcript (non-protein coding)
ZBTB17 zinc finger and BTB domain containing 17
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2