tumor-suppressor-proteins Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

349 proteins co-occuring with the biological term tumor-suppressor-proteins in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANKRD17 ankyrin repeat domain 17
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APLF aprataxin and PNKP like factor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATXN1 ataxin 1
AURKA aurora kinase A
AURKB aurora kinase B
AVEN apoptosis, caspase activation inhibitor
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BANP BTG3 associated nuclear protein
BARD1 BRCA1 associated RING domain 1
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCLAF1 BCL2-associated transcription factor 1
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BLM Bloom syndrome, RecQ helicase-like
BMPR1A bone morphogenetic protein receptor, type IA
BMX BMX non-receptor tyrosine kinase
BRCA1 breast cancer 1, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTG2 BTG family, member 2
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB3 BUB3 mitotic checkpoint protein
C1QBP complement component 1, q subcomponent binding protein
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCDC6 coiled-coil domain containing 6
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDC73 cell division cycle 73
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPA centromere protein A
CEP164 centrosomal protein 164kDa
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLSPN claspin
COPS6 COP9 signalosome subunit 6
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CROCC ciliary rootlet coiled-coil, rootletin
CTBP1 C-terminal binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL5 cullin 5
CYLD cylindromatosis (turban tumor syndrome)
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DBF4 DBF4 zinc finger
DCC DCC netrin 1 receptor
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DLC1 DLC1 Rho GTPase activating protein
DLG1 discs, large homolog 1 (Drosophila)
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F1 E2F transcription factor 1
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF6 eukaryotic translation initiation factor 6
ELAVL1 ELAV like RNA binding protein 1
ELK1 ELK1, member of ETS oncogene family
ENAH enabled homolog (Drosophila)
EP300 E1A binding protein p300
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
EWSR1 EWS RNA-binding protein 1
EYA3 EYA transcriptional coactivator and phosphatase 3
EZR ezrin
FAM129A family with sequence similarity 129, member A
FANCD2 Fanconi anemia, complementation group D2
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHIT fragile histidine triad
FLCN folliculin
FLT3 fms-related tyrosine kinase 3
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GRB2 growth factor receptor-bound protein 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
GTSE1 G-2 and S-phase expressed 1
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1C histone cluster 1, H1c
HIST1H2AI histone cluster 1, H2ai
HIST1H2BB histone cluster 1, H2bb
HIST1H2BN histone cluster 1, H2bn
HIST1H3A histone cluster 1, H3a
HMGN1 high mobility group nucleosome binding domain 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSF1 heat shock transcription factor 1
HSPB1 heat shock 27kDa protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL2RB interleukin 2 receptor, beta
ING1 inhibitor of growth family, member 1
IP6K2 inositol hexakisphosphate kinase 2
IRF2 interferon regulatory factor 2
IRF8 interferon regulatory factor 8
IRS1 insulin receptor substrate 1
JAK3 Janus kinase 3
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KAT6A K(lysine) acetyltransferase 6A
KHSRP KH-type splicing regulatory protein
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LIG3 ligase III, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LRP6 low density lipoprotein receptor-related protein 6
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPT microtubule-associated protein tau
MARS methionyl-tRNA synthetase
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM7 minichromosome maintenance complex component 7
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MKL1 megakaryoblastic leukemia (translocation) 1
MOB1B MOB kinase activator 1B
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYL12B myosin, light chain 12B, regulatory
MYOD1 myogenic differentiation 1
NABP2 nucleic acid binding protein 2
NBN nibrin
NCOA3 nuclear receptor coactivator 3
NF2 neurofibromin 2 (merlin)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NHEJ1 nonhomologous end-joining factor 1
NKX3-1 NK3 homeobox 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUAK1 NUAK family, SNF1-like kinase, 1
NUSAP1 nucleolar and spindle associated protein 1
OPRK1 opioid receptor, kappa 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGR progesterone receptor
PHF20 PHD finger protein 20
PIAS1 protein inhibitor of activated STAT, 1
PIDD1 p53-induced death domain protein 1
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLK1 polo-like kinase 1
PML promyelocytic leukemia
PNKP polynucleotide kinase 3'-phosphatase
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRLR prolactin receptor
PRPF19 pre-mRNA processing factor 19
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD17 RAD17 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RAP1GAP RAP1 GTPase activating protein
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBM5 RNA binding motif protein 5
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RIN1 Ras and Rab interactor 1
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RNF7 ring finger protein 7
RPA2 replication protein A2, 32kDa
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX3 runt-related transcription factor 3
RXRA retinoid X receptor, alpha
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIRT1 sirtuin 1
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SNAI1 snail family zinc finger 1
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STK11 serine/threonine kinase 11
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STRAP serine/threonine kinase receptor associated protein
SYN1 synapsin I
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TACC3 transforming, acidic coiled-coil containing protein 3
TAGLN2 transgelin 2
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TCF3 transcription factor 3
TCP1 t-complex 1
TDP1 tyrosyl-DNA phosphodiesterase 1
TELO2 telomere maintenance 2
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TFEB transcription factor EB
THOC5 THO complex 5
TLK1 tousled-like kinase 1
TOB1 transducer of ERBB2, 1
TOB2 transducer of ERBB2, 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRIM28 tripartite motif containing 28
TRIO trio Rho guanine nucleotide exchange factor
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTC5 tetratricopeptide repeat domain 5
TWIST1 twist family bHLH transcription factor 1
UIMC1 ubiquitin interaction motif containing 1
USP10 ubiquitin specific peptidase 10
USP28 ubiquitin specific peptidase 28
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VRK1 vaccinia related kinase 1
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WRN Werner syndrome, RecQ helicase-like
WWC1 WW and C2 domain containing 1
WWOX WW domain containing oxidoreductase
WWTR1 WW domain containing transcription regulator 1
XPA xeroderma pigmentosum, complementation group A
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF148 zinc finger protein 148
ZNF420 zinc finger protein 420
ZNHIT1 zinc finger, HIT-type containing 1