Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. (Experimental Factor Ontology, EFO_0003271)
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13 genes associated with the disease tumor necrosis factor-alpha in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.