tubocurarine chloride-6351 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tubocurarine chloride-6351 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD2 abhydrolase domain containing 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ADCY6 adenylate cyclase 6
AIM1L absent in melanoma 1-like
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
APOL6 apolipoprotein L, 6
APOLD1 apolipoprotein L domain containing 1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATP9A ATPase, class II, type 9A
BLZF1 basic leucine zipper nuclear factor 1
CA5B carbonic anhydrase VB, mitochondrial
CFAP45 cilia and flagella associated protein 45
CLCN7 chloride channel, voltage-sensitive 7
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPNE7 copine VII
CREB3L1 cAMP responsive element binding protein 3-like 1
CRTC1 CREB regulated transcription coactivator 1
CSN3 casein kappa
CSPP1 centrosome and spindle pole associated protein 1
CTTN cortactin
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EHBP1L1 EH domain binding protein 1-like 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPB41L1 erythrocyte membrane protein band 4.1-like 1
FAM13A family with sequence similarity 13, member A
FCAR Fc fragment of IgA receptor
FKBP10 FK506 binding protein 10, 65 kDa
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GATA3 GATA binding protein 3
GLDC glycine dehydrogenase (decarboxylating)
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR107 G protein-coupled receptor 107
GRK5 G protein-coupled receptor kinase 5
GRM4 glutamate receptor, metabotropic 4
HCFC1 host cell factor C1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HMOX2 heme oxygenase 2
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOXC10 homeobox C10
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFT122 intraflagellar transport 122
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL27RA interleukin 27 receptor, alpha
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHK ketohexokinase (fructokinase)
KISS1 KiSS-1 metastasis-suppressor
LAMC2 laminin, gamma 2
LOC100131532 uncharacterized LOC100131532
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP2K7 mitogen-activated protein kinase kinase 7
MFGE8 milk fat globule-EGF factor 8 protein
MKL1 megakaryoblastic leukemia (translocation) 1
MRPS12 mitochondrial ribosomal protein S12
MST1L macrophage stimulating 1-like
MUC3B mucin 3B, cell surface associated
MYCNOS MYCN opposite strand
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NADK NAD kinase
NPTXR neuronal pentraxin receptor
NR2E3 nuclear receptor subfamily 2, group E, member 3
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUMA1 nuclear mitotic apparatus protein 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLK3 polo-like kinase 3
POFUT1 protein O-fucosyltransferase 1
PRAF2 PRA1 domain family, member 2
PRDX2 peroxiredoxin 2
PSKH1 protein serine kinase H1
REST RE1-silencing transcription factor
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SENP6 SUMO1/sentrin specific peptidase 6
SIDT2 SID1 transmembrane family, member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SS18 synovial sarcoma translocation, chromosome 18
STBD1 starch binding domain 1
TADA2A transcriptional adaptor 2A
TBXA2R thromboxane A2 receptor
TGFB1 transforming growth factor, beta 1
TMEM161A transmembrane protein 161A
TSC22D2 TSC22 domain family, member 2
TUBGCP2 tubulin, gamma complex associated protein 2
UBOX5 U-box domain containing 5
USB1 U6 snRNA biogenesis 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VWA1 von Willebrand factor A domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF44 zinc finger protein 44
ZNF444 zinc finger protein 444

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVR2A activin A receptor, type IIA
AFAP1 actin filament associated protein 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARL15 ADP-ribosylation factor-like 15
BAMBI BMP and activin membrane-bound inhibitor
BBS7 Bardet-Biedl syndrome 7
BOLA1 bolA family member 1
BPGM 2,3-bisphosphoglycerate mutase
C1QTNF1 C1q and tumor necrosis factor related protein 1
CDC37L1 cell division cycle 37-like 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CLEC2B C-type lectin domain family 2, member B
CLK2 CDC-like kinase 2
CRELD1 cysteine-rich with EGF-like domains 1
CUL9 cullin 9
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEAF1 DEAF1 transcription factor
ELOVL4 ELOVL fatty acid elongase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL7 F-box and leucine-rich repeat protein 7
FGD6 FYVE, RhoGEF and PH domain containing 6
FUZ fuzzy planar cell polarity protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR39 G protein-coupled receptor 39
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BC histone cluster 1, H2bc
HIST1H3B histone cluster 1, H3b
HOXA4 homeobox A4
HPS6 Hermansky-Pudlak syndrome 6
ISYNA1 inositol-3-phosphate synthase 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5C lysine (K)-specific demethylase 5C
KLK5 kallikrein-related peptidase 5
KRT75 keratin 75, type II
MAGEH1 melanoma antigen family H1
MCM3 minichromosome maintenance complex component 3
MEIS1 Meis homeobox 1
MNX1 motor neuron and pancreas homeobox 1
MUTYH mutY homolog
MYBBP1A MYB binding protein (P160) 1a
NCAPH non-SMC condensin I complex, subunit H
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFS1 NFS1 cysteine desulfurase
NID2 nidogen 2 (osteonidogen)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDGFD platelet derived growth factor D
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDZD2 PDZ domain containing 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIAS3 protein inhibitor of activated STAT, 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POMT2 protein-O-mannosyltransferase 2
PROSER1 proline and serine rich 1
PRPH peripherin
PTGFR prostaglandin F receptor (FP)
RAB4B RAB4B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASA2 RAS p21 protein activator 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REEP4 receptor accessory protein 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF170 ring finger protein 170
SCD5 stearoyl-CoA desaturase 5
SECISBP2 SECIS binding protein 2
SH3BGR SH3 domain binding glutamate-rich protein
SIX1 SIX homeobox 1
SLC25A40 solute carrier family 25, member 40
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC46A3 solute carrier family 46, member 3
SPEG SPEG complex locus
SRBD1 S1 RNA binding domain 1
SUN2 Sad1 and UNC84 domain containing 2
SYTL2 synaptotagmin-like 2
TBC1D12 TBC1 domain family, member 12
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TLN1 talin 1
TM7SF2 transmembrane 7 superfamily member 2
TPST2 tyrosylprotein sulfotransferase 2
TSPAN1 tetraspanin 1
TTC31 tetratricopeptide repeat domain 31
TUBA3C tubulin, alpha 3c
UVRAG UV radiation resistance associated
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
ZNF33B zinc finger protein 33B
ZNF571 zinc finger protein 571