tubocurarine chloride-2887 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tubocurarine chloride-2887 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACVR1B activin A receptor, type IB
AHI1 Abelson helper integration site 1
AK2 adenylate kinase 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARSD arylsulfatase D
ATF7IP activating transcription factor 7 interacting protein
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATM ATM serine/threonine kinase
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BCL6 B-cell CLL/lymphoma 6
BMP1 bone morphogenetic protein 1
C19ORF66 chromosome 19 open reading frame 66
C5AR2 complement component 5a receptor 2
CA4 carbonic anhydrase IV
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CES3 carboxylesterase 3
CFLAR CASP8 and FADD-like apoptosis regulator
COL5A2 collagen, type V, alpha 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERP44 endoplasmic reticulum protein 44
EXD3 exonuclease 3'-5' domain containing 3
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR137 G protein-coupled receptor 137
GUSBP3 glucuronidase, beta pseudogene 3
H2AFX H2A histone family, member X
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HFE hemochromatosis
HIST1H3E histone cluster 1, H3e
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
ICA1 islet cell autoantigen 1, 69kDa
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIMCH1 LIM and calponin homology domains 1
LIMK2 LIM domain kinase 2
LOC157562 uncharacterized LOC157562
LRRC37A3 leucine rich repeat containing 37, member A3
MCFD2 multiple coagulation factor deficiency 2
MECOM MDS1 and EVI1 complex locus
MED25 mediator complex subunit 25
MMP3 matrix metallopeptidase 3
MTRF1L mitochondrial translational release factor 1-like
NAIP NLR family, apoptosis inhibitory protein
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUMA1 nuclear mitotic apparatus protein 1
OGFR opioid growth factor receptor
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PCDH1 protocadherin 1
PCDHA9 protocadherin alpha 9
PDE4C phosphodiesterase 4C, cAMP-specific
PHOX2A paired-like homeobox 2a
PIDD1 p53-induced death domain protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAP2B RAP2B, member of RAS oncogene family
RASA3 RAS p21 protein activator 3
RBPMS RNA binding protein with multiple splicing
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNFT1 ring finger protein, transmembrane 1
RPL35A ribosomal protein L35a
RRBP1 ribosome binding protein 1
RUSC2 RUN and SH3 domain containing 2
SCN11A sodium channel, voltage gated, type XI alpha subunit
SDS serine dehydratase
SLCO4C1 solute carrier organic anion transporter family, member 4C1
STIM1 stromal interaction molecule 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEP1 telomerase-associated protein 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
TUBA3C tubulin, alpha 3c
TUBB7P tubulin, beta 7, pseudogene
UHRF1BP1L UHRF1 binding protein 1-like
VEGFB vascular endothelial growth factor B
ZBTB43 zinc finger and BTB domain containing 43
ZNF286A zinc finger protein 286A
ZNF446 zinc finger protein 446
ZNF484 zinc finger protein 484
ZNF652 zinc finger protein 652
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABI3BP ABI family, member 3 (NESH) binding protein
ACTG2 actin, gamma 2, smooth muscle, enteric
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALS2CL ALS2 C-terminal like
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAGE B melanoma antigen
C14ORF79 chromosome 14 open reading frame 79
CFAP70 cilia and flagella associated protein 70
CISH cytokine inducible SH2-containing protein
CNR2 cannabinoid receptor 2 (macrophage)
CRY2 cryptochrome circadian clock 2
CTRL chymotrypsin-like
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXXC4 CXXC finger protein 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF4 DDB1 and CUL4 associated factor 4
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDAR ectodysplasin A receptor
EPHA2 EPH receptor A2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN1 endoplasmic reticulum to nucleus signaling 1
EXOC6B exocyst complex component 6B
FBXL2 F-box and leucine-rich repeat protein 2
FGF23 fibroblast growth factor 23
FOSL1 FOS-like antigen 1
FOXI1 forkhead box I1
GADD45G growth arrest and DNA-damage-inducible, gamma
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H2BJ histone cluster 1, H2bj
HOXC10 homeobox C10
HOXC5 homeobox C5
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
INPP1 inositol polyphosphate-1-phosphatase
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
KIAA1107 KIAA1107
KLF2 Kruppel-like factor 2
KRT24 keratin 24, type I
LIME1 Lck interacting transmembrane adaptor 1
LOC729164 hCG1732469
LPPR2 lipid phosphate phosphatase-related protein type 2
LRP5 low density lipoprotein receptor-related protein 5
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD1 LY6/PLAUR domain containing 1
LYRM9 LYR motif containing 9
MED9 mediator complex subunit 9
MFSD12 major facilitator superfamily domain containing 12
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MNX1 motor neuron and pancreas homeobox 1
MTERF4 mitochondrial transcription termination factor 4
MVP major vault protein
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
ONECUT1 one cut homeobox 1
PADI1 peptidyl arginine deiminase, type I
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDE12 phosphodiesterase 12
PHF14 PHD finger protein 14
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLAC8 placenta-specific 8
PLD3 phospholipase D family, member 3
PLXNA3 plexin A3
PMP22 peripheral myelin protein 22
PODXL2 podocalyxin-like 2
PRR4 proline rich 4 (lacrimal)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PWAR5 Prader Willi/Angelman region RNA 5
RAB3A RAB3A, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
RYR1 ryanodine receptor 1 (skeletal)
SLC22A14 solute carrier family 22, member 14
SPIDR scaffolding protein involved in DNA repair
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TARP TCR gamma alternate reading frame protein
TESC tescalcin
TH tyrosine hydroxylase
TLR2 toll-like receptor 2
TMEM242 transmembrane protein 242
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSGA10 testis specific, 10
TTBK2 tau tubulin kinase 2
TUBG2 tubulin, gamma 2
UBQLN4 ubiquilin 4
UPP1 uridine phosphorylase 1
VEGFC vascular endothelial growth factor C
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB39 zinc finger and BTB domain containing 39
ZNF16 zinc finger protein 16
ZSCAN2 zinc finger and SCAN domain containing 2