troglitazone-2692 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the troglitazone-2692 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AFF4 AF4/FMR2 family, member 4
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF53 chromosome 17 open reading frame 53
C17ORF59 chromosome 17 open reading frame 59
C6ORF10 chromosome 6 open reading frame 10
CAB39L calcium binding protein 39-like
CASKIN2 CASK interacting protein 2
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLCA2 chloride channel accessory 2
CLDN14 claudin 14
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL1A1 collagen, type I, alpha 1
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
DDR1 discoidin domain receptor tyrosine kinase 1
DGKG diacylglycerol kinase, gamma 90kDa
ELL elongation factor RNA polymerase II
EMID1 EMI domain containing 1
FZD1 frizzled class receptor 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALR2 galanin receptor 2
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSN gelsolin
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2BJ histone cluster 1, H2bj
HOXB1 homeobox B1
HOXD10 homeobox D10
HOXD13 homeobox D13
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA2 heat shock 70kDa protein 2
IL12B interleukin 12B
INCENP inner centromere protein antigens 135/155kDa
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGB4 integrin, beta 4
JAG1 jagged 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KRT23 keratin 23, type I
KRT75 keratin 75, type II
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LOC57399 uncharacterized gastric protein ZA52P
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAP1B microtubule-associated protein 1B
MAPK7 mitogen-activated protein kinase 7
MDK midkine (neurite growth-promoting factor 2)
MET MET proto-oncogene, receptor tyrosine kinase
MID1 midline 1
MYO10 myosin X
NCOR2 nuclear receptor corepressor 2
NF2 neurofibromin 2 (merlin)
NRXN2 neurexin 2
OASL 2'-5'-oligoadenylate synthetase-like
PARD6A par-6 family cell polarity regulator alpha
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM1 PDZ and LIM domain 1
PIGR polymeric immunoglobulin receptor
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLG plasminogen
PPARA peroxisome proliferator-activated receptor alpha
PRO2964 uncharacterized protein PRO2964
PROL1 proline rich, lacrimal 1
PRSS21 protease, serine, 21 (testisin)
PTHLH parathyroid hormone-like hormone
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RHO rhodopsin
RNF122 ring finger protein 122
RPLP2 ribosomal protein, large, P2
RRBP1 ribosome binding protein 1
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SCAND2P SCAN domain containing 2 pseudogene
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNED1 sushi, nidogen and EGF-like domains 1
SPATA2L spermatogenesis associated 2-like
SPON1 spondin 1, extracellular matrix protein
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAB1 stabilin 1
SUGCT succinyl-CoA:glutarate-CoA transferase
TAPT1 transmembrane anterior posterior transformation 1
TLDC1 TBC/LysM-associated domain containing 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TUBA4B tubulin, alpha 4b
TUBB1 tubulin, beta 1 class VI
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ZNF225 zinc finger protein 225
ZNF385D zinc finger protein 385D
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADM adrenomedullin
ADTRP androgen-dependent TFPI-regulating protein
ARG1 arginase 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BHLHE40 basic helix-loop-helix family, member e40
BNC2 basonuclin 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C8ORF44 chromosome 8 open reading frame 44
C9ORF9 chromosome 9 open reading frame 9
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN5 calpain 5
CASS4 Cas scaffolding protein family member 4
CCDC92 coiled-coil domain containing 92
CCL2 chemokine (C-C motif) ligand 2
CD69 CD69 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COL15A1 collagen, type XV, alpha 1
CPNE7 copine VII
DDIT4 DNA-damage-inducible transcript 4
EDAR ectodysplasin A receptor
EHD3 EH-domain containing 3
EMILIN2 elastin microfibril interfacer 2
ENO2 enolase 2 (gamma, neuronal)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM120C family with sequence similarity 120C
FANCE Fanconi anemia, complementation group E
FBXL2 F-box and leucine-rich repeat protein 2
FILIP1L filamin A interacting protein 1-like
FRS3 fibroblast growth factor receptor substrate 3
FSD1 fibronectin type III and SPRY domain containing 1
GAA glucosidase, alpha; acid
GATA4 GATA binding protein 4
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2BH histone cluster 1, H2bh
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IBSP integrin-binding sialoprotein
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INHBE inhibin, beta E
IRX5 iroquois homeobox 5
JAM3 junctional adhesion molecule 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KRT8P12 keratin 8 pseudogene 12
LATS1 large tumor suppressor kinase 1
LRRC20 leucine rich repeat containing 20
MATK megakaryocyte-associated tyrosine kinase
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MNX1 motor neuron and pancreas homeobox 1
MRAS muscle RAS oncogene homolog
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYLIP myosin regulatory light chain interacting protein
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG1 N-myc downstream regulated 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI2 peptidyl arginine deiminase, type II
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POR P450 (cytochrome) oxidoreductase
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRDM12 PR domain containing 12
PSKH1 protein serine kinase H1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS16 regulator of G-protein signaling 16
RHOH ras homolog family member H
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC22A14 solute carrier family 22, member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SREBF1 sterol regulatory element binding transcription factor 1
STEAP4 STEAP family member 4
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM212 transmembrane protein 212
TMEM45A transmembrane protein 45A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TONSL tonsoku-like, DNA repair protein
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
UPB1 ureidopropionase, beta
ZFP30 ZFP30 zinc finger protein
ZNF76 zinc finger protein 76