triglyceride-rich lipoprotein particle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoproteinparticles transport lipids, which are non-covalently associated with the particles, in the blood. (Gene Ontology, GO_0034385)
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Genes

285 proteins co-occuring with the triglyceride-rich lipoprotein particle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
APOB apolipoprotein B 4.47626
LPL lipoprotein lipase 3.71345
APOE apolipoprotein E 3.55978
LPA lipoprotein, Lp(a) 2.91613
APOC3 apolipoprotein C-III 2.91329
COG2 component of oligomeric golgi complex 2 2.68769
APOA1 apolipoprotein A-I 2.63482
CETP cholesteryl ester transfer protein, plasma 2.55479
INS insulin 2.50644
LCAT lecithin-cholesterol acyltransferase 2.43423
APOA2 apolipoprotein A-II 2.34723
MTTP microsomal triglyceride transfer protein 2.27286
MYDGF myeloid-derived growth factor 2.19407
LDLR low density lipoprotein receptor 2.14132
LIPC lipase, hepatic 1.93204
APOC2 apolipoprotein C-II 1.85936
ALB albumin 1.83611
VLDLR very low density lipoprotein receptor 1.71684
PLTP phospholipid transfer protein 1.64314
APOC1 apolipoprotein C-I 1.61236
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.5972
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.58679
APOA5 apolipoprotein A-V 1.57588
USF1 upstream transcription factor 1 1.36527
CRP C-reactive protein, pentraxin-related 1.36417
SCARB1 scavenger receptor class B, member 1 1.28303
SREBF1 sterol regulatory element binding transcription factor 1 1.27027
CSN1S1 casein alpha s1 1.26709
DGAT2 diacylglycerol O-acyltransferase 2 1.2455
FASN fatty acid synthase 1.23713
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.23348
TGM4 transglutaminase 4 1.18954
CHD1L chromodomain helicase DNA binding protein 1-like 1.16389
LEP leptin 1.15569
PPARA peroxisome proliferator-activated receptor alpha 1.14494
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.11633
PON1 paraoxonase 1 1.11582
ANGPTL3 angiopoietin-like 3 1.06903
GCG glucagon 1.06347
DGAT1 diacylglycerol O-acyltransferase 1 1.05892
APOD apolipoprotein D 1.0569
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.04733
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.0403
LIPG lipase, endothelial 1.03879
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.01436
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 1.00744
APOF apolipoprotein F 1.00103
SHBG sex hormone-binding globulin 0.997595
CES1 carboxylesterase 1 0.98488
SREBF2 sterol regulatory element binding transcription factor 2 0.954483
ANGPTL4 angiopoietin-like 4 0.950189
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.944956
HCAR2 hydroxycarboxylic acid receptor 2 0.929833
COG1 component of oligomeric golgi complex 1 0.926543
PEMT phosphatidylethanolamine N-methyltransferase 0.921386
PPARG peroxisome proliferator-activated receptor gamma 0.913443
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.908785
SOAT1 sterol O-acyltransferase 1 0.905067
TGFA transforming growth factor, alpha 0.899036
SOD2 superoxide dismutase 2, mitochondrial 0.890707
MANF mesencephalic astrocyte-derived neurotrophic factor 0.885166
CD36 CD36 molecule (thrombospondin receptor) 0.869505
CEL carboxyl ester lipase 0.859392
TTPA tocopherol (alpha) transfer protein 0.839187
PCSK9 proprotein convertase subtilisin/kexin type 9 0.82863
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.827712
LIPE lipase, hormone-sensitive 0.818075
APOBR apolipoprotein B receptor 0.807982
PNLIP pancreatic lipase 0.797436
ALPPL2 alkaline phosphatase, placental-like 2 0.794229
ALPL alkaline phosphatase, liver/bone/kidney 0.793771
ALPP alkaline phosphatase, placental 0.793313
SDC2 syndecan 2 0.788733
SOAT2 sterol O-acyltransferase 2 0.787359
GPX4 glutathione peroxidase 4 0.777298
GPX5 glutathione peroxidase 5 0.774101
PLG plasminogen 0.769083
SCARB2 scavenger receptor class B, member 2 0.76726
PNPLA3 patatin-like phospholipase domain containing 3 0.764527
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.758615
CIDEB cell death-inducing DFFA-like effector b 0.757253
GPX1 glutathione peroxidase 1 0.754983
APOA4 apolipoprotein A-IV 0.75181
FABP2 fatty acid binding protein 2, intestinal 0.749999
GGT1 gamma-glutamyltransferase 1 0.746833
CAT catalase 0.741867
NPC1L1 NPC1-like 1 0.728389
PCYOX1 prenylcysteine oxidase 1 0.726599
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.69164
AADAC arylacetamide deacetylase 0.690764
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.684207
HMGA2 high mobility group AT-hook 2 0.681155
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.680284
RETN resistin 0.677238
ACSS2 acyl-CoA synthetase short-chain family member 2 0.674196
F3 coagulation factor III (thromboplastin, tissue factor) 0.670725
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.669858
IRF6 interferon regulatory factor 6 0.668559
ACLY ATP citrate lyase 0.663368
PCSK7 proprotein convertase subtilisin/kexin type 7 0.642715
LPIN2 lipin 2 0.642286
SAA1 serum amyloid A1 0.639717
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.638005
IL6 interleukin 6 0.637578
SCARF1 scavenger receptor class F, member 1 0.632878
TNF tumor necrosis factor 0.626909
RBP4 retinol binding protein 4, plasma 0.618406
MLXIPL MLX interacting protein-like 0.612048
LRP2 low density lipoprotein receptor-related protein 2 0.606128
CES3 carboxylesterase 3 0.599802
PLIN2 perilipin 2 0.598538
PLA2G1B phospholipase A2, group IB (pancreas) 0.594332
PLAT plasminogen activator, tissue 0.591392
G6PD glucose-6-phosphate dehydrogenase 0.581758
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.578416
DLL1 delta-like 1 (Drosophila) 0.572578
LTF lactotransferrin 0.566754
PNPLA2 patatin-like phospholipase domain containing 2 0.561358
HBA2 hemoglobin, alpha 2 0.553905
VCAM1 vascular cell adhesion molecule 1 0.551838
INSR insulin receptor 0.540706
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.537827
HBA1 hemoglobin, alpha 1 0.530028
LPIN1 lipin 1 0.528798
ACE angiotensin I converting enzyme 0.525931
F2 coagulation factor II (thrombin) 0.523885
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.51327
FOXO1 forkhead box O1 0.497826
SAA2 serum amyloid A2 0.497015
CP ceruloplasmin (ferroxidase) 0.493775
PLA2G12B phospholipase A2, group XIIB 0.493775
LYPLA1 lysophospholipase I 0.480855
TTR transthyretin 0.48005
APOH apolipoprotein H (beta-2-glycoprotein I) 0.465998
GSR glutathione reductase 0.463598
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.462398
SUGP1 SURP and G patch domain containing 1 0.448451
FADS1 fatty acid desaturase 1 0.447259
GLT8D2 glycosyltransferase 8 domain containing 2 0.446862
SRR serine racemase 0.4425
PON2 paraoxonase 2 0.44052
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.438542
IGF1 insulin-like growth factor 1 (somatomedin C) 0.438542
TF transferrin 0.433407
CTSC cathepsin C 0.432618
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 0.426711
CPT1A carnitine palmitoyltransferase 1A (liver) 0.423567
SAA4 serum amyloid A4, constitutive 0.415337
FADS2 fatty acid desaturase 2 0.413773
APOM apolipoprotein M 0.413382
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.410259
IRS1 insulin receptor substrate 1 0.409479
CCDC92 coiled-coil domain containing 92 0.408699
LPIN3 lipin 3 0.404804
APOC4 apolipoprotein C-IV 0.395873
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.386979
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.386593
HP haptoglobin 0.381584
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.378891
CCL2 chemokine (C-C motif) ligand 2 0.377738
MGAM maltase-glucoamylase 0.377738
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.375818
HPR haptoglobin-related protein 0.364713
PTH parathyroid hormone 0.362422
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.360133
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.354042
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.353282
PROS1 protein S (alpha) 0.349484
ICAM1 intercellular adhesion molecule 1 0.349105
ALLC allantoicase 0.346071
ACACA acetyl-CoA carboxylase alpha 0.343421
LMF1 lipase maturation factor 1 0.341907
FGF21 fibroblast growth factor 21 0.341907
CBY1 chibby homolog 1 (Drosophila) 0.338884
GGT2 gamma-glutamyltransferase 2 0.333979
RELN reelin 0.329084
LRP1B low density lipoprotein receptor-related protein 1B 0.325702
APOO apolipoprotein O 0.325702
SDC1 syndecan 1 0.312224
GLP1R glucagon-like peptide 1 receptor 0.311851
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.308122
ZNF664 zinc finger protein 664 0.308122
TRIB1 tribbles pseudokinase 1 0.302168
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.293637
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.286983
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.286245
APOL1 apolipoprotein L, 1 0.27998
PON3 paraoxonase 3 0.278877
SULF2 sulfatase 2 0.273734
METTL7B methyltransferase like 7B 0.273734
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 0.272633
CD44 CD44 molecule (Indian blood group) 0.272633
STARD8 StAR-related lipid transfer (START) domain containing 8 0.271533
GPBAR1 G protein-coupled bile acid receptor 1 0.268603
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.267871
LRP10 low density lipoprotein receptor-related protein 10 0.267505
IRS2 insulin receptor substrate 2 0.266774
REN renin 0.26385
TM6SF2 transmembrane 6 superfamily member 2 0.262755
IL1B interleukin 1, beta 0.261296
STAP2 signal transducing adaptor family member 2 0.251839
CROT carnitine O-octanoyltransferase 0.250751
SAR1B secretion associated, Ras related GTPase 1B 0.24713
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.243519
G6PC glucose-6-phosphatase, catalytic subunit 0.241356
IFNL3 interferon, lambda 3 0.238837
C3 complement component 3 0.234533
SORT1 sortilin 1 0.233459
LTB4R leukotriene B4 receptor 0.229888
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.228108
F9 coagulation factor IX 0.226331
PPARD peroxisome proliferator-activated receptor delta 0.226331
P4HB prolyl 4-hydroxylase, beta polypeptide 0.224913
AMY2A amylase, alpha 2A (pancreatic) 0.223497
POMC proopiomelanocortin 0.219265
PCSK5 proprotein convertase subtilisin/kexin type 5 0.217511
ACACB acetyl-CoA carboxylase beta 0.21716
FABP4 fatty acid binding protein 4, adipocyte 0.215761
SELE selectin E 0.209513
TSC22D4 TSC22 domain family, member 4 0.208137
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.205399
TCHH trichohyalin 0.200999
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.198991
LSR lipolysis stimulated lipoprotein receptor 0.198325
VAT1 vesicle amine transport 1 0.194698
F12 coagulation factor XII (Hageman factor) 0.194371
GCK glucokinase (hexokinase 4) 0.192423
CER1 cerberus 1, DAN family BMP antagonist 0.190175
CSTB cystatin B (stefin B) 0.187646
ZNHIT1 zinc finger, HIT-type containing 1 0.187333
THADA thyroid adenoma associated 0.184853
HNF4A hepatocyte nuclear factor 4, alpha 0.184547
TXNL4B thioredoxin-like 4B 0.183328
STX8 syntaxin 8 0.182723
SPINK5 serine peptidase inhibitor, Kazal type 5 0.182422
GSTA3 glutathione S-transferase alpha 3 0.182122
NOS3 nitric oxide synthase 3 (endothelial cell) 0.181823
GSTA2 glutathione S-transferase alpha 2 0.18093
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 0.18093
GSTA4 glutathione S-transferase alpha 4 0.180634
CD5 CD5 molecule 0.179167
GSTA1 glutathione S-transferase alpha 1 0.178877
A1CF APOBEC1 complementation factor 0.177439
DAND5 DAN domain family member 5, BMP antagonist 0.177154
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.176024
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.175466
BHMT betaine--homocysteine S-methyltransferase 0.174361
LEPR leptin receptor 0.174087
GPX3 glutathione peroxidase 3 0.172201
ACSL1 acyl-CoA synthetase long-chain family member 1 0.17141
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.170371
DNAH10 dynein, axonemal, heavy chain 10 0.169604
ACSL3 acyl-CoA synthetase long-chain family member 3 0.169604
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.168598
TGM5 transglutaminase 5 0.167125
REPIN1 replication initiator 1 0.163865
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.16233
MLX MLX, MAX dimerization protein 0.161484
CD81 CD81 molecule 0.159658
GIP gastric inhibitory polypeptide 0.158315
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.157218
PSAT1 phosphoserine aminotransferase 1 0.139483
JMJD1C jumonji domain containing 1C 0.138636
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.1382
PRSS30P protease, serine, 30, pseudogene 0.138066
BTNL2 butyrophilin-like 2 0.136621
INSM2 insulinoma-associated 2 0.136307
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.136013
WFDC2 WAP four-disulfide core domain 2 0.13511
FBXO44 F-box protein 44 0.134694
DMBX1 diencephalon/mesencephalon homeobox 1 0.134473
GMPR guanosine monophosphate reductase 0.133976
PXDN peroxidasin 0.133818
SBF2 SET binding factor 2 0.133765
PCCB propionyl CoA carboxylase, beta polypeptide 0.133413
HES6 hes family bHLH transcription factor 6 0.130961
SPAG11A sperm associated antigen 11A 0.130891
MALL mal, T-cell differentiation protein-like 0.130247
MXD4 MAX dimerization protein 4 0.130191
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.129699
SPAG11B sperm associated antigen 11B 0.129679
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.129602
CXCL14 chemokine (C-X-C motif) ligand 14 0.128897
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.128855
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.128102