tricuspid valve insufficiency Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A tricuspid valve disease that is characterized by failure of the heart's tricuspid valve to close properly during systole. As a result, with each heart beat, blood is pumped out from the right side of the heart in the opposite direction to normal. (Human Disease Ontology, DOID_4080)
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Genes

92 genes co-occuring with the disease tricuspid valve insufficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PDZK1IP1 PDZK1 interacting protein 1 1.7496
CPB1 carboxypeptidase B1 (tissue) 1.67457
PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.54539
TRAT1 T cell receptor associated transmembrane adaptor 1 1.3276
SLC38A4 solute carrier family 38, member 4 1.22215
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 1.103
YME1L1 YME1-like 1 ATPase 1.08034
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 1.0109
BLVRA biliverdin reductase A 0.99233
NEBL nebulette 0.870415
FAT3 FAT atypical cadherin 3 0.861409
ALB albumin 0.820437
DHDH dihydrodiol dehydrogenase (dimeric) 0.819616
CA5B carbonic anhydrase VB, mitochondrial 0.783116
SMAD9 SMAD family member 9 0.766759
COX5A cytochrome c oxidase subunit Va 0.753306
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.733001
NPPA natriuretic peptide A 0.724098
GIN1 gypsy retrotransposon integrase 1 0.718039
IFI44 interferon-induced protein 44 0.700321
TNNI3 troponin I type 3 (cardiac) 0.6939
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.678302
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.673518
WRNIP1 Werner helicase interacting protein 1 0.666755
A1BG alpha-1-B glycoprotein 0.663181
BIN2 bridging integrator 2 0.6608
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.658026
FBN1 fibrillin 1 0.65763
TUBGCP4 tubulin, gamma complex associated protein 4 0.650113
NOTCH1 notch 1 0.6214
ACVRL1 activin A receptor type II-like 1 0.615529
HAND2 heart and neural crest derivatives expressed 2 0.596012
ALYREF Aly/REF export factor 0.595233
NPPB natriuretic peptide B 0.591727
CD59 CD59 molecule, complement regulatory protein 0.583163
CUTA cutA divalent cation tolerance homolog (E. coli) 0.581996
ADORA2B adenosine A2b receptor 0.57655
OPN3 opsin 3 0.567609
TBX2 T-box 2 0.558674
ENO3 enolase 3 (beta, muscle) 0.550911
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.532701
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.528835
SALL1 spalt-like transcription factor 1 0.524588
PLAT plasminogen activator, tissue 0.517649
OSCAR osteoclast associated, immunoglobulin-like receptor 0.513033
INVS inversin 0.483985
ETV3 ets variant 3 0.442795
PRB3 proline-rich protein BstNI subfamily 3 0.441666
CDK11A cyclin-dependent kinase 11A 0.44129
MAP9 microtubule-associated protein 9 0.440538
ERAS ES cell expressed Ras 0.433021
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.42139
PHB2 prohibitin 2 0.420641
ADRBK1 adrenergic, beta, receptor kinase 1 0.420266
SRSF2 serine/arginine-rich splicing factor 2 0.415024
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.405678
STAB2 stabilin 2 0.402318
RAB27A RAB27A, member RAS oncogene family 0.400453
GYPA glycophorin A (MNS blood group) 0.395235
CRP C-reactive protein, pentraxin-related 0.393001
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.389281
GP2 glycoprotein 2 (zymogen granule membrane) 0.362978
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.353763
OXTR oxytocin receptor 0.34384
PRRC2A proline-rich coiled-coil 2A 0.343473
IGLV2-8 immunoglobulin lambda variable 2-8 0.325187
ACE angiotensin I converting enzyme 0.322637
FTL ferritin, light polypeptide 0.31464
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.31464
FTH1 ferritin, heavy polypeptide 1 0.31464
EDN1 endothelin 1 0.311739
TNNT2 troponin T type 2 (cardiac) 0.311014
TIMP1 TIMP metallopeptidase inhibitor 1 0.30342
UTS2 urotensin 2 0.282225
CA8 carbonic anhydrase VIII 0.275445
TCN2 transcobalamin II 0.273664
FBN2 fibrillin 2 0.269753
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.253831
BCHE butyrylcholinesterase 0.248554
LAX1 lymphocyte transmembrane adaptor 1 0.23492
NAAA N-acylethanolamine acid amidase 0.220766
GPANK1 G patch domain and ankyrin repeats 1 0.208914
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.197099
DNAH8 dynein, axonemal, heavy chain 8 0.194548
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.190168
GLS glutaminase 0.190168
PLN phospholamban 0.179239
CHGA chromogranin A 0.173314
MCAM melanoma cell adhesion molecule 0.172799
ADAM17 ADAM metallopeptidase domain 17 0.171286
VCP valosin containing protein 0.163729
MMP1 matrix metallopeptidase 1 0.162306