trichostatin A-5987 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-5987 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP3 BAI1-associated protein 3
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CASC1 cancer susceptibility candidate 1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPF1 D4, zinc and double PHD fingers family 1
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EPAS1 endothelial PAS domain protein 1
EPOR erythropoietin receptor
FADS3 fatty acid desaturase 3
FKBP1B FK506 binding protein 1B, 12.6 kDa
FN1 fibronectin 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRAMD1C GRAM domain containing 1C
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
ITM2C integral membrane protein 2C
JAKMIP2 janus kinase and microtubule interacting protein 2
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MUC3B mucin 3B, cell surface associated
MXRA7 matrix-remodelling associated 7
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKNOX2 PBX/knotted 1 homeobox 2
PMEL premelanosome protein
PRPH peripherin
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPL3L ribosomal protein L3-like
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SORBS1 sorbin and SH3 domain containing 1
SOX9 SRY (sex determining region Y)-box 9
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYBU syntabulin (syntaxin-interacting)
SYT11 synaptotagmin XI
TBC1D2 TBC1 domain family, member 2
TPMT thiopurine S-methyltransferase
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM3 tripartite motif containing 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UNC119 unc-119 homolog (C. elegans)
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BANP BTG3 associated nuclear protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C19ORF54 chromosome 19 open reading frame 54
C9ORF91 chromosome 9 open reading frame 91
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CHMP6 charged multivesicular body protein 6
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EFNA1 ephrin-A1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EVPL envoplakin
FAIM Fas apoptotic inhibitory molecule
FAM155B family with sequence similarity 155, member B
FAM57A family with sequence similarity 57, member A
FAS Fas cell surface death receptor
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GRWD1 glutamate-rich WD repeat containing 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
KIAA0753 KIAA0753
LMNB1 lamin B1
LPAR2 lysophosphatidic acid receptor 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC8D leucine rich repeat containing 8 family, member D
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRIP1 nuclear receptor interacting protein 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
POGK pogo transposable element with KRAB domain
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPAN peter pan homolog (Drosophila)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SBNO2 strawberry notch homolog 2 (Drosophila)
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SHARPIN SHANK-associated RH domain interactor
SLC35F2 solute carrier family 35, member F2
SMG9 SMG9 nonsense mediated mRNA decay factor
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STC2 stanniocalcin 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR76 WD repeat domain 76
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF574 zinc finger protein 574
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787